\n![\"RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg.gif\")
<\/figure><\/div>\n\n<\/div>\n
<\/figure><\/div>\n\n<\/div>\n\u5173\u952e\u8bcd\uff1a\u9057\u4f20\u68c0\u6d4b \u6280\u672f\u8fed\u4ee3<\/div>\n
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\u9ad8\u901a\u91cf\u57fa\u56e0\u6d4b\u5e8f\u6280\u672f\u52a0\u901f\u57fa\u56e0\u68c0\u6d4b\u4e34\u5e8a\u5e94\u7528\u3002\u9664\u4e86\u6d4b\u5e8f\uff0c\u8fd8\u6709\u54ea\u4e9b\u5206\u5b50\u9057\u4f20\u5b66\u5b9e\u9a8c\u6280\u672f\uff1f\u9664\u4e86NIPT\u8fd8\u6709\u54ea\u4e9b\u65b0\u6280\u672f\u5e94\u7528\u8fdb\u5c55\uff1f\u57fa\u56e0\u68c0\u6d4b\u5386\u7ecf\u4e24\u6b21\u201c\u6682\u505c\u4ee4\u201d\u540e\u5c06\u5982\u4f55\u53d1\u5c55\uff1f2018\u5e746\u670811\u65e5\uff0c\u5728\u5317\u4eac\u53ec\u5f00\u7684\u201cillumina\u4e2d\u56fd\u6d4b\u5e8f\u6280\u672f\u5341\u5468\u5e74\u4ea4\u6d41\u4f1a\u201d\u4e0a\uff0c\u56fd\u5bb6\u4ea7\u524d\u8bca\u65ad\u4e13\u5bb6\u9ec4\u5c1a\u5fd7\u6559\u6388\u4f5c\u4e86\u7cfb\u7edf\u5206\u4eab\u3002\u7ecf\u8fc7\u6388\u6743\uff0c\u57fa\u56e0\u6167\u6574\u7406\u8981\u70b9\u5982\u4e0b\u3002<\/div>\n
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\n\n
\n![\"RmFicvQBAkgBxwD6q0icYKEheGhGxLyiacusUXXEKhkXhqnvcoHiasAvCVaIE6Oe42Lm5mpD1IvG3Hxzico5xCaicwnQ\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgBxwD6q0icYKEheGhGxLyiacusUXXEKhkXhqnvcoHiasAvCVaIE6Oe42Lm5mpD1IvG3Hxzico5xCaicwnQ.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u9ec4\u5c1a\u5fd7\u00a0 \u6559\u6388<\/div>\n
WHO\u9057\u4f20\u75c5\u793e\u533a\u63a7\u5236\u5408\u4f5c\u4e2d\u5fc3\u4e3b\u4efb\u3001\u56fd\u5bb6\u4ea7\u524d\u8bca\u65ad\u4e13\u5bb6<\/div>\n
1\u3001\u5206\u5b50\u9057\u4f20\u5b66\u5b9e\u9a8c\u6280\u672f<\/div>\n\n
\n![\"?wx_fmt=jpeg\"\/](\"https:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/RmFicvQBAkgBxwD6q0icYKEheGhGxLyiacusPmWf6hByAaLZd4EPMCNQJumJzib3CIgIORtpW1XU5RFmvAexFmnia8A\/?wx_fmt=jpeg\")
<\/figure><\/div>\n\n
2\u3001\u6d4b\u5e8f\u6280\u672f\u8fed\u4ee3<\/div>\n
\u2022\u00a0\u7b2c\u4e8c\u4ee3\u6d4b\u5e8f\u6280\u672f\uff1a\u5e73\u884c\u6d4b\u5e8f<\/div>\n\n
\n![\"?wx_fmt=png\"\/](\"https:\/\/mmbiz.qpic.cn\/mmbiz_png\/RmFicvQBAkgAqxnlZqQZ3F4v0ARibdibrlpOa1PVyibzGkBJVyfxk8BOghuSJaBzO9dcD5pbbrUrQe9BxiadBChSO9A\/?wx_fmt=png\")
<\/figure><\/div>\n\n
\u56fe1\uff0c\u6d4b\u5e8f\u4eea<\/div>\n\n
\n![\"RmFicvQBAkgAqxnlZqQZ3F4v0ARibdibrlpCA4y2wq66WxArPeM0fnYuzdK3sTmPw91YosK4zR8uGf3oPmyewHuyQ\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAqxnlZqQZ3F4v0ARibdibrlpCA4y2wq66WxArPeM0fnYuzdK3sTmPw91YosK4zR8uGf3oPmyewHuyQ.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe2\uff0c\u4f0d\u5efa\uff1a\u4e8c\u4ee3\u6d4b\u5e8f\u6280\u672f\uff1a\u6570\u636e\u89e3\u8bfb\u53ca\u5e94\u7528\uff0c2012<\/div>\n
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\u2022\u00a0\u00a0\u7b2c\u4e09\u4ee3\u6d4b\u5e8f\u6280\u672f\uff1a<\/div>\n
2008\u5e74\u4e4b\u540e\uff0c\u4e09\u4ee3\u6d4b\u5e8f\u6280\u672f\u6982\u5ff5\u88ab\u63d0\u51fa\uff0c\u6838\u5fc3\u662f\u5355\u5206\u5b50\u5b9e\u65f6\u6d4b\u5e8f\u4e3a\u4e3b\u8981\u7279\u70b9\uff0c\u4ee5 Pacific Bio \u516c\u53f8 SMRT \u6280\u672f\u3001Helicos \u516c\u53f8 tSMS \u6280\u672f\u3001\u548c Nanopore \u516c\u53f8\u7684\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u6280\u672f\u4e3a\u4ee3\u8868\u3002<\/div>\n
\u2022\u00a0\u00a0\u7b2c\u56db\u4ee3\u6d4b\u5e8f\u6280\u672f\uff1a<\/div>\n
\u6709\u4eba\u5c06\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u6280\u672f\u79f0\u4e3a\u7b2c\u56db\u4ee3\u6d4b\u5e8f\u6280\u672f\uff0cDNA\u5355\u94fe\u7a7f\u8d8a\u7eb3\u7c73\u5b54\u65f6\u4e0d\u540c\u78b1\u57fa\u5f15\u8d77\u7684\u7535\u5b66\u53c2\u6570\u7684\u53d8\u5316\u91cf\u4e5f\u4e0d\u540c\uff0c\u53ef\u4ee5\u5bf9\u5e94\u76f8\u5e94\u78b1\u57fa\u7c7b\u578b\u3002\u65e0\u9700DNA\u5408\u6210\u53cd\u5e94\u800c\u76f4\u63a5\u5bf9DNA\u5e8f\u5217\u8fdb\u884c\u8bfb\u53d6\u3002<\/div>\n
\u00a0<\/div>\n
3\u3001\u65b0\u6280\u672f\u7684\u63a8\u52a8\u4f5c\u7528<\/div>\n\n
\n![\"RmFicvQBAkgCiayhaBXoLHs2yUoG1vkRZhnh5cTWwY8YjGfqmxCeesic708D1jviaR8bbdIySzdBS0MqjQRGb9n5Ug\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCiayhaBXoLHs2yUoG1vkRZhnh5cTWwY8YjGfqmxCeesic708D1jviaR8bbdIySzdBS0MqjQRGb9n5Ug.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u5c0f\u7247\u6bb5\u6d4b\u5e8f\u5305\u62ec\u5c0fRNA\u6d4b\u5e8f\u548c\u6e38\u79bbDNA\u6d4b\u5e8f\uff0c\u540e\u8005\u5982 cfDNA\uff08NIPT\uff09\u548c ctDNA\u3002\u4e8c\u4ee3\u6d4b\u5e8f\u7684\u51fa\u73b0\u89e3\u51b3\u4e86\u6b64\u524d\u5c0fRNA\u6d4b\u5e8f\u65e0\u6cd5\u5b9e\u65bd\u7684\u95ee\u9898\u3002\u5982\u679c\u6ca1\u6709\u4e8c\u4ee3\u6d4b\u5e8f\uff0ccfDNA\u548cctDNA\u65e0\u6cd5\u6d4b\u5e8f\u3002\u672a\u6765\u56db\u4e94\u5e74\u5185\uff0cNIPT\u6216\u8bb8\u4f1a\u9000\u51fa\u5386\u53f2\u821e\u53f0\uff0c\u800c\u4ee5\u5355\u7ec6\u80de\u4e3a\u68c0\u6d4b\u624b\u6bb5\u7684\u80ce\u513f\u7ec6\u80de\u7684\u5bcc\u96c6\u3001\u68c0\u6d4b\u5c06\u6210\u4e3a\u4ea7\u524d\u8bca\u65ad\u7684\u4e00\u4e2a\u65b9\u5f0f\u3002<\/div>\n
\u00a0<\/div>\n
4\u3001\u57fa\u56e0\u68c0\u6d4b\u5386\u7ecf\u4e24\u6b21\u201c\u6682\u505c\u4ee4\u201d<\/div>\n
\u2022\u00a0\u00a0\u6682\u505cPCR\u6280\u672f\uff1a<\/div>\n
1\uff09\u7f3a\u4e4f\u77e5\u8bc6\u548c\u6280\u672f\uff0c\u884c\u4e1a\u9700\u8981\u5b66\u4e60<\/div>\n
2\uff09\u5229\u76ca\u9a71\u52a8\uff0c\u7f3a\u4e4f\u89c4\u8303\u548c\u89c4\u77e9<\/div>\n
\u2022\u00a0\u00a0\u6682\u505c\u6d4b\u5e8f\u6280\u672f\uff1a<\/div>\n
1\uff09\u4ea7\u524d\u8bca\u65ad\u548cSanger\u6280\u672f\u5747\u88ab\u6682\u505c<\/div>\n
2\uff09\u6280\u672f\u6709\u5f85\u8fdb\u6b65\uff0cNIPT\u73b0\u5728\u5df2\u7ecf\u65e5\u6e10\u6210\u719f<\/div>\n
3\uff09\u5229\u76ca\u9a71\u52a8\u53ef\u80fd\u662f\u4e3b\u56e0\uff1a\u68c0\u6d4b\u516c\u53f8\u7f51\u7f57\u6837\u54c1\uff0c\u51fa\u73b0\u4e71\u5c40\uff1b\u975e\u533b\u5b66\u68c0\u6d4b\u6405\u5c40<\/div>\n
2002\u5e74\uff0c\u536b\u751f\u90e8\u53d1\u5e03\u300a\u4e34\u5e8a\u57fa\u56e0\u6269\u589e\u68c0\u9a8c\u5b9e\u9a8c\u5ba4\u7ba1\u7406\u6682\u884c\u529e\u6cd5\u300b\uff0c\u660e\u786e\u89c4\u5b9a\u672a\u7ecf\u4e13\u5bb6\u7ec4\u9a8c\u6536\u5408\u683c\u5e76\u62a5\u7701\u7ea7\u536b\u751f\u884c\u653f\u90e8\u95e8\u5907\u6848\u7684\u533b\u7597\u673a\u6784\u4e0d\u5f97\u64c5\u81ea\u5f00\u5c55\u4e34\u5e8a\u57fa\u56e0\u6269\u589e\u68c0\u9a8c\u9879\u76ee\u3002<\/div>\n
2014\u5e74\uff0c\u56fd\u5bb6\u98df\u836f\u76d1\u7ba1\u603b\u5c40\u3001\u56fd\u5bb6\u536b\u8ba1\u59d4\u8054\u5408\u53d1\u51fa\u901a\u77e5\uff0c\u53eb\u505c\u4e86\u5305\u62ec\u4ea7\u524d\u57fa\u56e0\u68c0\u6d4b\u5728\u5185\u7684\u57fa\u56e0\u6d4b\u5e8f\u3002\u6309\u7167\u901a\u77e5\u8981\u6c42\uff0c\u81ea\u53d1\u5e03\u4e4b\u65e5\u8d77\uff0c\u5305\u62ec\u4ea7\u524d\u57fa\u56e0\u68c0\u6d4b\u5728\u5185\u7684\u6240\u6709\u57fa\u56e0\u6d4b\u5e8f\u4ea7\u54c1\u53ca\u5176\u6280\u672f\uff0c\u5982\u7528\u4e8e\u75be\u75c5\u7684\u9884\u9632\u3001\u8bca\u65ad\u3001\u76d1\u62a4\u3001\u6cbb\u7597\u76d1\u6d4b\u3001\u5065\u5eb7\u72b6\u6001\u8bc4\u4ef7\u548c\u9057\u4f20\u6027\u75be\u75c5\u7684\u9884\u6d4b\uff0c\u9700\u7ecf\u98df\u54c1\u836f\u54c1\u76d1\u7ba1\u90e8\u95e8\u5ba1\u6279\u6ce8\u518c\uff0c\u5e76\u7ecf\u536b\u751f\u8ba1\u751f\u884c\u653f\u90e8\u95e8\u6279\u51c6\u6280\u672f\u51c6\u5165\u65b9\u53ef\u5e94\u7528\u3002\u5df2\u7ecf\u5e94\u7528\u7684\uff0c\u5fc5\u987b\u7acb\u5373\u505c\u6b62\u3002<\/div>\n
\u00a0<\/div>\n
5\u3001\u57fa\u56e0\u6d4b\u5e8f\u7684\u8d8b\u52bf<\/div>\n
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1\uff09\u5df2\u77e5\u57fa\u56e0\u672a\u77e5\u53d8\u5f02\u7684\u9274\u5b9a\uff1a<\/div>\n
\u539f\u5148\u5206\u5b50\u514b\u9686\u6d4b\u5e8f\u3001PCR\u4ea7\u7269\u6d4b\u5e8f\uff08\u514b\u9686\u6d4b\u5e8f\u3001\u53cc\u94fe\u76f4\u63a5\u6d4b\u5e8f\uff09<\/div>\n
2\uff09\u672a\u77e5\u57fa\u56e0\u7684\u786e\u5b9a\uff1a<\/div>\n
\u539f\u5148\u4f9d\u8d56\u5bb6\u7cfb\uff0c\u91c7\u7528\u8fde\u9501\u5206\u6790\uff0c\u518d\u7f29\u77ed\u533a\u57df\uff0c\u5019\u9009\u57fa\u56e0\u7a81\u53d8\uff1b\u73b0\u5728NGS\uff0ctrio-WES<\/div>\n
3\uff09\u81ea\u52a8\u5316\u5206\u6790\u3001\u5de5\u4e1a\u5316\u751f\u4ea7\u6210\u4e3a\u53ef\u80fd\uff0c\u4f7f\u9057\u4f20\u68c0\u6d4b\u8fdb\u5165\u9ad8\u901f\u53d1\u5c55\uff1a\u5305\u62ecCMA\u3001NGS<\/div>\n
\u2022\u00a0 \u6d4b\u5e8f\u7ed3\u679c\u8d8a\u6765\u8d8a\u96be\u89e3\u8bfb<\/div>\n
1\uff09\u5927\u6570\u636e\u7684\u4ea7\u751f\uff0c\u5bf9\u751f\u7269\u4fe1\u606f\u5b66\u7684\u4f9d\u8d56\u6027\u66f4\u5927\uff0c\u5bf9\u751f\u7269\u4fe1\u606f\u4eba\u624d\u9700\u6c42\u52a0\u5927\u3002<\/div>\n
2\uff09\u53d8\u5f02\u6027\u8d28\u7684\u786e\u8ba4\u4ecd\u7136\u662f\u74f6\u9888\uff0c\u4e2d\u56fd\u4eba\u7684\u5f88\u591a\u53d8\u5f02\uff0c\u7279\u522b\u662f\u9519\u4e49\u53d8\u5f02\u5c1a\u4e0d\u6e05\u695a\u3002<\/div>\n
3\uff09NGS\u5b58\u5728\u77ed\u677f\u3002<\/div>\n
4\uff09\u4e34\u5e8a\u8868\u578b\u548c\u68c0\u6d4b\u7ed3\u679c\u7684\u5bf9\u63a5\u5b58\u5728\u56f0\u96be\uff0c\u4e34\u5e8a\u533b\u751f\u7684\u4f5c\u7528\u4e0d\u53ef\u66ff\u4ee3\u3002<\/div>\n
\u00a0<\/div>\n
6\u3001\u5206\u5b50\u8bca\u65ad\u6280\u672f\u5728\u4e34\u5e8a\u7684\u5e94\u7528<\/div>\n
\u2022\u00a0\u00a0\u4e34\u5e8a\u62df\u8bca\u5e94\u5c3d\u91cf\u51c6\u786e<\/div>\n
1\uff09\u68c0\u6d4b\u65b9\u6848\u7684\u786e\u5b9a<\/div>\n
2\uff09NGS\u6570\u636e\u89e3\u8bfb\uff0c\u662f\u6570\u636e\u4e0e\u4e34\u5e8a\u8868\u578b\u7684\u5bf9\u63a5<\/div>\n
3\uff09\u533b\u751f\u5373\u4f7f\u4e0d\u80fd\u505a\u51fa\u8bca\u65ad\uff0c\u4e5f\u5e94\u63d0\u4f9b\u8be6\u7ec6\u7684\u4e34\u5e8a\u8868\u578b\u63cf\u8ff0\uff0c\u4ee5\u4fbf\u68c0\u6d4b\u673a\u6784\u6839\u636e\u63d0\u4f9b\u7684\u8868\u578b\u8fdb\u884c\u5206\u6790\u3002<\/div>\n
\u2022\u00a0\u00a0\u68c0\u6d4b\u9879\u76ee\u9009\u62e9<\/div>\n
1\uff09\u4f18\u5148\u9009\u62e9\u7b80\u5355\u7a33\u5b9a\u3001\u7ed3\u679c\u51c6\u786e\u7684\u9002\u5b9c\u6280\u672f\uff0c\u91c7\u7528\u9002\u5b9c\u7684\u68c0\u6d4b\u65b9\u6848<\/div>\n
2\uff09\u9009\u62e9NGS\u9700\u6ce8\u610fpanel\u8986\u76d6\u7387\u3002<\/div>\n
\u00a0<\/div>\n
7\u3001\u4ecd\u5f85\u89e3\u51b3\u7684\u95ee\u9898<\/div>\n
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1\uff09\u56fd\u4eba\u6570\u636e\u7f3a\u4e4f<\/div>\n
2\uff09\u5efa\u8bae\u5efa\u7acb\u6570\u636e\u5171\u4eab\u548c\u8fd0\u4f5c\u673a\u5236<\/div>\n
\u2022\u00a0\u00a0\u7f3a\u4e4f\u751f\u7269\u5b66\u5b9e\u9a8c\u8bc1\u636e<\/div>\n
\u5efa\u8bae\u5efa\u7acb\u53d8\u5f02\u529f\u80fd\u9a8c\u8bc1\u7684\u751f\u7269\u5b9e\u9a8c\u4e2d\u5fc3\uff0c\u5373\u65b0\u7684\u201c\u7b2c\u4e09\u65b9\u201d\u00a0\u00a0\u00a0\u00a0<\/div>\n
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1\uff09\u8868\u578b\u63cf\u8ff0\u4e0d\u5145\u5206\uff0c\u4e0d\u89c4\u8303<\/div>\n
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\u00a0<\/div>\n
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\u4e13\u680f\u4f5c\u8005<\/div>\n
\u5206\u6790\u5e08<\/div>\n
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GeneClub<\/div>\n
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