{"id":9638,"date":"2018-09-21T22:00:49","date_gmt":"2018-09-21T14:00:49","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100007535&idx=1&sn=052be27fa551de9368184ddc6f6f78ac&chksm=6b72acd85c0525ce70071c57af13488330a4d462c8837466a568ac9872c793080efb9c86c47a#rd"},"modified":"2026-04-08T10:38:55","modified_gmt":"2026-04-08T02:38:55","slug":"495253","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2018\/09\/21\/495253\/","title":{"rendered":"CSCO\u77ad\u671b | \u5927\u4f1a\u7b2c\u4e8c\u65e5\u514d\u75ab\u6cbb\u7597\/CDE\/\u751f\u7269\u6807\u5fd7\u7269\u7b495\u5927\u4e13\u573a\u7b14\u8bb0"},"content":{"rendered":"

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\"RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg\"\/<\/figure><\/div>\n\n<\/div>\n
<\/div>\n
\u5173\u952e\u8bcd\/2018CSCO\u7b2c\u4e8c\u65e5 \u4f1a\u8bae\u7b14\u8bb0 \u00a0 \u00a0\u6587\/\u57fa\u56e0\u6167<\/div>\n
<\/div>\n
2018\u5e749\u670821\u65e5\uff0c\u7b2c\u4e8c\u5341\u4e00\u5c4a\u5168\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u5927\u4f1a\u66a82018\u5e74\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u5b66\u672f\u5e74\u4f1a\u8fce\u6765\u7b2c\u4e8c\u5929\u7cbe\u5f69\u65e5\u7a0b\uff0c\u8fd9\u573a\u80bf\u7624\u9886\u57df\u5e74\u5ea6\u5b66\u672f\u76db\u4f1a\u6301\u7eed3\u5929\uff0c\u517175\u4e2a\u5b66\u672f\u4e13\u573a\u300190\u573a\u536b\u661f\u4f1a\u3002\u7ee7\u6628\u65e5\u5206\u4eab\u5927\u4f1a\u9996\u65e5\u76d1\u7ba1\/\u80ba\u764c\/\u4e73\u817a\u764c\/\u667a\u6167\u533b\u7597\u7b495\u4e2a\u5b66\u672f\u4e13\u573a\u5e72\u8d27\u7b14\u8bb0\uff08\u8be6\u60c5<\/a>\uff09\uff0c\u4ee5\u4e0b\u662f\u4eca\u65e5\u62a5\u9053\u7684\u5927\u4f1a\u7b2c\u4e8c\u65e5\u4e13\u573a\u7b14\u8bb0\uff0c\u57fa\u56e0\u6167\u5c06\u6301\u7eed\u66f4\u65b0\u62a5\u9053\u91cd\u8981\u5b66\u672f\u4e13\u573a\u5185\u5bb9\uff0c\u6b22\u8fce\u5173\u6ce8\u3002<\/div>\n
<\/div>\n
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\"?wx_fmt=jpeg\"\/<\/figure><\/div>\n\n
\u56fe\uff0cCSCO 2018\u4f1a\u573a<\/div>\n
19\u670821\u65e5\u5b66\u672f\u4e13\u573a<\/div>\n
\u514d\u75ab\u6cbb\u7597\u4e13\u573a<\/div>\n
\uff08\u65f6\u95f4\uff1a9\u670821\u65e5 8:30-12:00\uff09<\/div>\n\n
\n
\"RmFicvQBAkgBzh6zDj6DUh7M7uLEqmu4Ctp5UPR4TKYqmNbibiceNicqY7xdQuRsfXbMPhnBATTzgywibApzr4JwHhA\"\/<\/figure><\/div>\n\n
\u25c6\u00a0\u90ed\u519b \u6559\u6388\uff08\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u4ece\u9ed1\u8272\u7d20\u7624\u770b\u672a\u6765\u514d\u75ab\u6cbb\u7597\u53d1\u5c55\u300b<\/div>\n
1. Keynote006\u66f4\u65b04\u5e74\u751f\u5b58\u6570\u636e\uff0c\u603b\u4f5341.7%\uff0c\u521d\u6cbb\u60a3\u800544.3%\uff0c\u9996\u4e2a\u83b7\u5f973\u5e74\u751f\u5b58\u7387\u6570\u636e\u7684\u5b9e\u4f53\u7624\u3002<\/div>\n
2. Checkmate067:68%(81\/120)\uff0c85%(23\/27)\u53ca30%(14\/47)\u7684\u60a3\u8005\u56e0\u6bd2\u6027\u53cd\u5e94\u5206\u522b\u4e2d\u65adNIVO+IPI\uff0cNIVO\u53caIPI\u7684\u6cbb\u7597\uff0c\u4ecd\u83b7\u5f97CR\u6216PR\u3002<\/div>\n
3. \u8bc6\u522b\u80bf\u7624\uff08\u6297\u539f\u91ca\u653e\uff0c\u6297\u539f\u63d0\u5448\uff09\uff0c\u514d\u75ab\u7ec6\u80de\u6fc0\u6d3b\uff08T\u7ec6\u80de\uff0cNK\u7ec6\u80de\uff0cT\u8c03\u8282\u7ec6\u80de\uff0c\u9ad3\u7cfb\uff09\uff0c\u79fb\u81f3\u76ee\u6807\uff08\u95f4\u8d28\uff0c\u5316\u5b66\u8d8b\u5316\uff09\uff0c\u6d88\u706d\u80bf\u7624\uff08\u7ec6\u80de\u4ecb\u5bfc\uff0c\u5316\u5b66\u4ecb\u5bfc\uff09\u3002<\/div>\n
4. Pembrolizumab+Epacadostat\uff1a\u6ca1\u6709\u5145\u8db3\u7684II\u671f\u7814\u7a76\u7ed3\u679c\u4e0d\u8981\u7740\u6025\u8fdb\u884cIII\u671f\u8bd5\u9a8c\u3002<\/div>\n
5. \u65b0\u8f85\u52a9Nivo+Ipi\u5e8f\u8d2fNivo\u8f85\u52a9\u6cbb\u7597\uff0c\u65b0\u8f85\u52a9\u6cbb\u7597\u63a2\u7d22\u5448\u5149\u660e\u4e4b\u8def\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u53f6\u5b9a\u4f1f \u6559\u6388\uff08\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u5c3f\u8def\u4e0a\u76ae\u764c\u514d\u75ab\u6cbb\u7597\u8fdb\u5c55\u300b<\/div>\n
1. ICI\u63d0\u9ad8\u4e86\u665a\u671f\u4e8c\u7ebf\u5c3f\u8def\u4e0a\u76ae\u764c\u7684\u7597\u6548\uff0c\u6cbb\u7597\u7684\u5ba2\u89c2\u5e94\u7b54\u7387\u4ece12%\u6700\u9ad8\u63d0\u5347\u81f327%\u3002<\/div>\n
2. PD-L1\u8868\u8fbe\u5bf9\u8180\u80f1\u764c\u5177\u6709\u9884\u540e\u610f\u4e49\u3002<\/div>\n
3. \u514d\u75ab\u6cbb\u7597\u7684\u4f18\u5316\u7b56\u7565\uff1a\u7cbe\u51c6\u7684\u60a3\u8005\u4eba\u7fa4&\u8054\u5408\u7597\u6cd5\uff08\u514d\u75ab\u7597\u6cd5+\u5316\u7597\u3001\u514d\u75ab+\u514d\u75ab\u3001\u514d\u75ab+\u653e\u7597\u3001\u514d\u75ab+\u9776\u5411\u7b49\uff09\u3002<\/div>\n
4. \u514d\u75ab\u6cbb\u7597\u7684\u65b9\u5411\uff1a\u5411\u65e9\u671f\u9636\u6bb5\u79ef\u6781\u63a2\u7d22\uff0c\u5168\u7a0b\u6539\u5584\u8180\u80f1\u764c\u60a3\u8005\u7684\u6cbb\u7597\u83b7\u76ca\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u5f20\u529b \u6559\u6388 \uff08\u4e2d\u5c71\u5927\u5b66\u80bf\u7624\u9632\u6cbb\u4e2d\u5fc3\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300airAE\u5206\u7ea7\u53ca\u4e34\u5e8a\u7ba1\u7406\u300b<\/div>\n
1. irAE\u65e9\u671f\u8bca\u65ad\u53ca\u5206\u7ea7\u7ba1\u7406\u5bf9I-O\u6cbb\u7597\u81f3\u5173\u91cd\u8981\u3002<\/div>\n
2. \u514d\u75ab\u6cbb\u7597\u5b89\u5168\u6027\u7ba1\u7406\u7684\u4e94\u5927\u652f\u67f1\uff1aPREVENT\u3001ANTICIPATE\u3001DETECT\u3001TREAT\u3001MONITOR\u3002<\/div>\n
3. \u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u4e0e\u5316\u7597\u3001\u9776\u5411\u6cbb\u7597\u7684\u673a\u5236\u4e0d\u540c\uff0c\u5bfc\u81f4\u7684\u4e0d\u826f\u53cd\u5e94\u8c31\u4e0d\u540c\uff0c\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u8010\u53d7\u6027\u597d\u3002<\/div>\n
4. \u65e9\u671f\u8bca\u65ad\u548c\u5206\u7ea7\u7ba1\u7406\u5f88\u91cd\u8981\uff0c\u5728\u5408\u7406\u5e94\u7528\u63a7\u5236\u63aa\u65bd\u7684\u524d\u63d0\u4e0birAE\u5927\u90e8\u5206\u662f\u53ef\u9006\u7684\u3002<\/div>\n
5. \u7279\u6b8a\u4eba\u7fa4\u7684\u7ba1\u7406\u9700\u8981\u8c28\u614e\uff0c\u6839\u636e\u4e2a\u4f53\u5316\u7684\u98ce\u9669\u83b7\u76ca\u6765\u51b3\u5b9a\u6cbb\u7597\u9009\u62e9\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6 \u5b59\u5efa\u56fd \u6559\u6388 \uff08\u9646\u519b\u519b\u533b\u5927\u5b66\u65b0\u6865\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u8010\u836f\u673a\u5236\u4e0e\u5904\u7406\u5bf9\u7b56\u300b<\/div>\n
1. \u514d\u75ab\u6cbb\u7597\u53ef\u80fd\u5e26\u6765\u957f\u671f\u751f\u5b58\uff0c\u665a\u671fNSCLC\u4e2d5\u5e74OS\u8fbe\u523016%\uff0c\u7136\u800c\u4ecd\u6709\u90e8\u5206\u60a3\u8005\u5b58\u5728\u514d\u75ab\u8010\u836f\u3002<\/div>\n
2. \u514d\u75ab\u8010\u836f\u5927\u90fd\u8868\u73b0\u4e3a\u539f\u53d1\u6027\u8010\u836f\uff0c\u800c\u4e00\u65e6\u6cbb\u7597\u6709\u6548\uff0c\u5927\u90e8\u5206\u60a3\u8005\u80fd\u591f\u6301\u4e45\u83b7\u76ca\uff0c\u5373\u83b7\u5f97\u6027\u8010\u836f\u76f8\u5bf9\u8f83\u5c11\u53d1\u751f\u3002\u8010\u836f\u673a\u5236\u53ef\u80fd\u662f\u80bf\u7624\u5185\u5728\u539f\u56e0\u6216\u80bf\u7624\u4ee5\u5916\u7684\u673a\u5236\u5bfc\u81f4\u3002<\/div>\n
3. \u8054\u5408\u6cbb\u7597\u6216\u7ec6\u80de\u6cbb\u7597\u662f\u514b\u670d\u514d\u75ab\u5355\u836f\u8010\u836f\u7684\u6709\u6548\u7b56\u7565\u3002\u8054\u5408\u6cbb\u7597\u8fdb\u5c55\u98de\u901f\uff0c\u5927\u91cfIII\u671f\u4e34\u5e8a\u83b7\u8bc1\u3002\u7ec6\u80de\u6cbb\u7597\u3001CAR-T\u5728\u5b9e\u4f53\u7624\u7597\u6548\u5f85\u8bc1\u5b9e\uff0c\u6709\u6f5c\u5728\u6bd2\u6027\uff1bTIL\u521d\u6b65\u7597\u6548\u786e\u5207\uff0c\u53ef\u80fd\u6210\u4e3a\u6cbb\u7597\u5b9e\u4f53\u7624\u7684\u6709\u529b\u6b66\u5668\u3002<\/div>\n
4. \u672a\u6765\uff0c\u4e9f\u9700\u66f4\u591a\u7814\u7a76\u660e\u786e\u8010\u836f\u673a\u5236\u53ca\u76f8\u5173\u5904\u7406\u5bf9\u7b56\u3002<\/div>\n
\u00a0<\/div>\n
\u80ba\u764c\u514d\u75ab\u6cbb\u7597\u4e13\u573a<\/div>\n
\uff08\u65f6\u95f4\uff1a9\u670821\u65e5 8:30-12:00\uff09<\/div>\n\n
\n
\"?wx_fmt=jpeg\"\/<\/figure><\/div>\n\n
\u25c6 \u5468\u5f69\u5b58\uff08\u4e0a\u6d77\u5e02\u80ba\u79d1\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u4e00\u7ebf\u6cbb\u7597\uff0c\u5355\u836f\u8fd8\u662f\u8054\u5408\u300b<\/div>\n
1. \u4e00\u7ebf\u5e94\u7528\u5e15\u535a\u5229\u73e0\u5355\u6297\u6cbb\u7597\u6bd4\u4e00\u7ebf\u5316\u7597\u51fa\u73b0PD\uff0c\u518d\u4ea4\u53c9\u63a5\u53d7\u5e15\u535a\u5229\u73e0\u5355\u6297\u6cbb\u7597\uff0c\u663e\u8457\u5ef6\u957f\u60a3\u8005OS\u3002<\/div>\n
2. PD-1\/PD-L1\u901a\u8def\u4f5c\u4e3a\u6297\u80bf\u7624\u514d\u75ab\u53cd\u5e94\u7ec8\u672b\u6b65\u9aa4\u7684\u9650\u901f\u6b65\u9aa4\uff0c\u662f\u8054\u5408\u6cbb\u7597\u7684\u57fa\u77f3\u3002<\/div>\n
3. \u5316\u7597\u836f\u7269\u7684\u514d\u75ab\u8c03\u8282\u4f5c\u7528\uff1a\u5316\u7597\u8bf1\u5bfc\u80bf\u7624\u7ec6\u80de\u53d1\u751f\u514d\u75ab\u539f\u6027\u6b7b\u4ea1\uff0c\u91ca\u653e\u80bf\u7624\u6297\u539f\uff1b\u5316\u7597\u5e72\u6270\u80bf\u7624\u7ec6\u80de\u7684\u514d\u75ab\u9003\u9038\u673a\u5236\u3002<\/div>\n
4. IO\u5355\u836f\u9700\u8981\u9009\u62e9\uff1aPD-L1\uff1e50%\u4ee5\u4e0a\u60a3\u8005\uff0cKeytruda\u5355\u836f\u6cbb\u7597\u3002<\/div>\n
6. IO+IO\uff1a\u5728\u9ad8TMB\u7684\u75c5\u4eba\u4e2d\uff0c\u6539\u5584PFS\u3002<\/div>\n
7. IO\u8054\u5408\u5176\u4ed6\u836f\u7269\u6b63\u5728\u8fdb\u884c\u4e2d\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u738b\u6d01\uff08\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u5982\u4f55\u63d0\u9ad8\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u4e8c\u7ebf\u6cbb\u7597\u7684\u7597\u6548\u300b<\/div>\n
1. \u76ee\u524d\u4ecd\u6709\u7ea660%\u7684NSCLC\u60a3\u8005\u6cbb\u7597\u624b\u6bb5\u975e\u5e38\u6709\u9650\uff0c\u751f\u5b58\u9884\u540e\u4e0d\u7406\u60f3\u3002<\/div>\n
2. \u591a\u79cdPD-1\/PD-L1\u6291\u5236\u5242\u5df2\u6210\u4e3a\u65b0\u4e8c\u7ebfNSCLC\u6cbb\u7597\u6807\u51c6\u3002<\/div>\n
3. \u672a\u6765\u4e24\u4e2a\u65b9\u5411\uff1a\u901a\u8fc7biomarker\u7684\u7814\u7a76\u7cbe\u51c6\u8bc6\u522b\u83b7\u76ca\u4eba\u7fa4\uff0c\u4ee5\u4fc3\u8fdb\u4e8c\u7ebf\u514d\u75ab\u6cbb\u7597\u7684\u7597\u6548\uff1b\u7cbe\u7ec6\u5316\u7684\u5206\u5c42\u57fa\u7840\u4e0a\u7684\u5408\u7406\u7684\u8054\u5408\u7b56\u7565\u662f\u672a\u6765\u63a2\u7d22\u65b9\u5411\u3002<\/div>\n
4. CA209-003\u548cKeynote-010\u7814\u7a76\u8868\u660e\uff1aPD-1\u6291\u5236\u5242\u6cbb\u75972\u5e74\u540e\u505c\u836f\uff0c\u5927\u90e8\u5206\u60a3\u8005\u4ecd\u5728\u6301\u7eed\u5e94\u7b54\uff1b\u6cbb\u7597\u65f6\u95f4\u4ecd\u662f\u76ee\u524d\u4e9f\u5f85\u89e3\u51b3\u7684\u95ee\u9898\u3002<\/div>\n
5. HPD\u4e0e\u80bf\u7624\u8d1f\u8377\u3001\u6cbb\u7597\u7ebf\u6570\u65e0\u76f8\u5173\u6027\uff1bPD-1\u6291\u5236\u5242\u548cPD-L1\u6291\u5236\u5242\u5728HPD\u4e0a\u65e0\u660e\u663e\u5dee\u5f02\u3002<\/div>\n
6. I-O\u6cbb\u7597\u72ec\u7279\u7684\u53cd\u5e94\u6a21\u5f0f\uff1a\u5047\u6027\u8fdb\u5c55\u3002\u5f53\u6dcb\u5df4\u7ec6\u80de\u6d78\u6da6\u80bf\u7624\u65f6\uff0c\u80bf\u5757\u53ef\u80fd\u8868\u73b0\u4e3a\u589e\u5927\u6216\u65b0\u75c5\u7076\u51fa\u73b0\uff1b\u56e0\u4e3a\u8fbe\u5230\u9002\u5e94\u6027\u514d\u75ab\u53cd\u5e94\u9700\u8981\u4e00\u5b9a\u65f6\u95f4\uff0c\u5047\u6027\u8fdb\u5c55\u53ef\u80fd\u8868\u73b0\u4e3a\u80bf\u7624\u6301\u7eed\u589e\u957f\u76f4\u81f3\u8fbe\u5230\u4e00\u5b9a\u7a0b\u5ea6\u7f13\u89e3\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u5362\u94c0\uff08\u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u5728\u65e9\u671f\u60a3\u8005\u7684\u5e94\u7528\u300b<\/div>\n
1. \u65e9\u671fNSCLC\u60a3\u8005\u80bf\u7624\u5fae\u73af\u5883\u4e2d\uff1aPD-1\/PD-L1\u8f74\u660e\u663e\u6fc0\u6d3b\uff1b\u80bf\u7624\u7ec4\u7ec7\u4e2dPD-L1\u8f83\u764c\u65c1\u660e\u663e\u5347\u9ad8\uff1bTIL\u8868\u8fbePD-1\u660e\u663e\u5347\u9ad8\u3002<\/div>\n
2. \u65e9\u671f\u80ba\u817a\u764c\u80bf\u7624\u5fae\u73af\u5883\u4e2d\uff0c\u5177\u6709\u72ec\u7279\u7684\u80bf\u7624\u514d\u75ab\u7b7e\u540d\u3002<\/div>\n
3. \u65e9\u671f\u7684\u80bf\u7624\u5fae\u73af\u5883\u4e2d\uff0c\u7279\u522b\u662fT\u7ec6\u80de\u3001NK\u548c\u80bf\u7624\u6d78\u6da6\u9ad3\u7cfb\u7ec6\u80de\u7684\u514d\u75ab\u7ec6\u80de\u7ec4\u6210\u548c\u8868\u578b\uff0c\u5df2\u53d1\u751f\u6539\u53d8\u3002\u80bf\u7624\u514d\u75ab\u6cbb\u7597\uff0c\u4e0d\u5e94\u4ec5\u9650\u4e8e\u764c\u75c7\u665a\u671f\u9636\u6bb5\u3002<\/div>\n
4. Durvalumab\u5de9\u56fa\u6cbb\u7597\u7597\u6548\uff1aPFS\u8f83\u5bf9\u7167\u7ec4\u5ef6\u957f\u8fd11\u5e74\uff0c\u57283\u671fNSCLC\u6cbb\u7597\u4e2d\u662f\u53f2\u65e0\u524d\u4f8b\u7684\uff1bPFS\u663e\u8457\u5ef6\u957f\u610f\u5473\u7740\u4e0eOS\u7684\u83b7\u76ca\u5bc6\u5207\u76f8\u5173\uff1b\u8111\u8f6c\u79fb\u53d1\u751f\u7387\u660e\u663e\u964d\u4f4e\uff0c\u5bf9\u7167\u7ec4\u662fDurvalumab\u7814\u7a76\u7ec4\u7684\u4e24\u500d\u3002Durvalumab\u5de9\u56fa\u6cbb\u7597\u6bd2\u526f\u53cd\u5e94\uff08\u7814\u7a76\u7ec4vs\u5bf9\u7167\u7ec4\uff09\uff1a\u56e0\u80ba\u708e\u5bfc\u81f4\u6cbb\u7597\u4e2d\u65ad6.3% vs 4.3%\u3002<\/div>\n
5. \u653e\u7597\u80fd\u4e0a\u8c03\u6216\u6539\u5584\u80bf\u7624\u5fae\u73af\u5883\u4e2d\uff1aMHC-I\uff08\u589e\u5f3a\u514d\u75ab\u53cd\u5e94\uff09\uff1b\u9ad8\u8fc1\u79fb\u7387\u65cf\u86cb\u767d\uff08HMGB1\uff0c\u4fc3\u8fdb\u514d\u75ab\u53cd\u5e94\u7684\u708e\u75c7\u56e0\u5b50\uff09\uff1b\u5fae\u8840\u7ba1\u7ed3\u6784\uff08\u63d0\u9ad8\u5c40\u90e8\u5fae\u73af\u5883\u6cbb\u7597\u6548\u80fd\uff09\uff1bPD-L1\u8868\u8fbe\uff0c\u653e\u75972-3\u5468\uff0c\u7ea630% NSCLC\u60a3\u8005\u5faa\u73af\u80bf\u7624\u7ec6\u80dePD-L1\u8868\u8fbe\u589e\u52a0\uff0c\u8fd9\u4e9bCTC\u6e90\u81ea\u653e\u7597\u9776\u533a\u7684\u80bf\u7624\u7ec6\u80de\u3002<\/div>\n
6. \u653e\u7597\u80fd\u589e\u654f\u514d\u75ab\u6cbb\u7597\u7684\u6548\u5e94\uff1a\u5c40\u90e8\u6cbb\u7597\u6548\u679c\u3001\u8fdc\u4f4d\u6548\u5e94\uff08abscopal effect\uff09\u3002<\/div>\n
7. \u653e\u7597\uff1a\u5c06\u51b7\u80bf\u7624\u8f6c\u53d8\u4e3a\u70ed\u80bf\u7624\uff0c\u8bf1\u5bfc\u80bf\u7624\u7ec6\u80de\u6b7b\u4ea1\uff0c\u91ca\u653e\u5371\u9669\u4fe1\u53f7\uff0c\u4fc3\u8fdbDC\u6210\u719f\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u738b\u54f2\u6d77\uff08\u5c71\u4e1c\u7701\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u514d\u75ab\u6291\u5236\u5242\u4e0d\u826f\u53cd\u5e94\u7684\u5904\u7406\u300b<\/div>\n
1. \u514d\u75ab\u76f8\u5173\u4e0d\u826f\u53cd\u5e94\u7684\u7279\u70b9\uff1a\u5668\u5b98\u7279\u5f02\u6027\uff08\u7ed3\u80a0\u708e\u3001\u809d\u708e\u3001\u80ba\u708e\u3001\u7532\u4f4e\uff09\u3001\u4e00\u822c\u6027\uff08\u75b2\u4e4f\u3001\u8179\u6cfb\u3001\u76ae\u75b9\uff09\u3001\u5176\u4ed6\u4e0e\u7cfb\u7edf\u6027\u708e\u75c7\u76f8\u5173\u7684\u4e0d\u826f\u53cd\u5e94\u7b49\u3002<\/div>\n
2. \u5bf9\u4e34\u5e8a\u533b\u751f\u5904\u7406\u6bd2\u6027\u7684\u603b\u4f53\u5efa\u8bae\uff08\u4ee5\u4e0b\u4e3a\u90e8\u5206\uff09\uff1a<\/div>\n
1\uff09\u60a3\u8005\u53ca\u5bb6\u5c5e\u5728\u6cbb\u7597\u524d\u3001\u6cbb\u7597\u968f\u8bbf\u8fc7\u7a0b\u4e2d\uff0c\u5e94\u53ca\u65f6\u5f97\u5230\u6700\u65b0\u7684\u6709\u5173\u514d\u75ab\u6cbb\u7597\u673a\u5236\u3001\u53ef\u80fd\u53d1\u751f\u7684irAEs\u7684\u6559\u80b2\u3002<\/div>\n
2\uff09\u5bf9\u6cbb\u7597\u76f8\u5173\u65b0\u7684\u6b63\u88c5\u4fdd\u6301\u9ad8\u5ea6\u6000\u7591\u6001\u5ea6\u3002<\/div>\n
3\uff09\u4e00\u822c\u800c\u8a00\uff0c\u9664\u67d0\u4e9b\u795e\u7ecf\u3001\u8840\u6db2\u548c\u5fc3\u810f\u6bd2\u6027\u4e4b\u5916\uff0c\u5176\u4ed61\u5ea6\u6bd2\u6027\u65f6ICPi\u5e94\u5bc6\u5207\u76d1\u89c6\u4e0b\u7ee7\u7eed\u3002<\/div>\n
3. \u514d\u75ab\u76f8\u5173\u6bd2\u6027\u7684\u5904\u7406\u57fa\u672c\u539f\u5219\u6c47\u603b\uff08\u6839\u636e\u6bd2\u6027\u53d1\u751f\u90e8\u4f4d\u3001\u6bd2\u6027\u7ea7\u522b\u8fdb\u884c\u7ec6\u8282\u8c03\u6574\uff0c\u4ee5\u4e0b\u4e3a\u90e8\u5206\uff09\uff1a<\/div>\n
1\uff09\u4e0e\u76f8\u5173\u4e13\u5bb6\u5408\u4f5c\u3002<\/div>\n
2\uff09ICPis\uff1a\u7ee7\u7eed\u3001\u6682\u505c\u3001\u56de\u590d\u3001\u505c\u7528\u3002<\/div>\n
3\uff09\u6da6\u80a4\u5242\uff1a\u5916\u7528\u3002<\/div>\n
4\uff09\u7c7b\u56fa\u9187\u6fc0\u7d20\uff1a\u7528\u6cd5\u3001\u5242\u91cf\u3001\u836f\u6548\u5f3a\u5ea6\u3001\u7f13\u6162\u505c\u836f\u3002<\/div>\n
5\uff09\u6297\u7ec4\u80fa\u836f\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u7a0b\u9896\uff08\u5409\u6797\u7701\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u5c0f\u7ec6\u80de\u80ba\u764c\u514d\u75ab\u6cbb\u7597\u8fdb\u5c55\u300b<\/div>\n
1. Nivo\u83b7\u6279\u6cbb\u7597SCLC\u6807\u5fd7\u7740\u514d\u75ab\u6cbb\u7597\u5df2\u6210\u4e3aSCLC\u6cbb\u7597\u7684\u7a81\u7834\u53e3\uff0c\u514d\u75ab\u6cbb\u7597\u6b63\u5728\u6539\u53d8SCLC\u6cbb\u7597\u7684\u6574\u4f53\u5e03\u5c40\u3002<\/div>\n
2. CheckMate 032\u7814\u7a76\uff1a\u5728\u975e\u9009\u62e9\u7684\u60a3\u8005\u4e2d\uff0cNivo\u8054\u5408\u6cbb\u7597\u8f83\u5355\u836f\u6cbb\u7597\u6709\u66f4\u9ad8\u7684\u7f13\u89e3\u7387\uff1b\u65e0\u8bba\u6cbb\u7597\u7ebf\u6570\uff0c\u94c2\u7c7b\u654f\u611f\u8fd8\u662f\u8010\u836f\u60a3\u8005Nivo\u8054\u5408ipi\u5747\u6709\u826f\u597d\u5e94\u7b54\uff1b\u9ad8TMB\u60a3\u8005\u6709\u66f4\u9ad8\u7684ORR\u3002<\/div>\n
3. Keynote 158\u7814\u7a76\uff1a\u5728\u975e\u9009\u62e9\u4eba\u7fa4\u4e2d\uff0cPemb\u5355\u836f\u6cbb\u7597\u590d\u53d1SCLC\u83b7\u5f97\u6301\u4e45\u7597\u6548\uff0812\u4e2a\u6708PFS\u548cOS\u5206\u522b\u4e3a16.8%\u300140.2%\uff09\uff1bPD-L1\u9633\u6027SCLC\uff0cPemb\u5355\u836f\u6cbb\u7597\u5177\u6709\u66f4\u9ad8\u7684ORR\u548c\u6301\u4e45\u5e94\u7b54\u3002<\/div>\n
4. \u4e0d\u540c\u836f\u7269\u7814\u7a76\u7b56\u7565\u4e0d\u540c\uff0c\u9009\u62e9\u7684\u6807\u5fd7\u7269\u4e0d\u540c\uff0c\u76ee\u524dSCLC\u4e2d\u514d\u75ab\u6cbb\u7597\u7684\u6807\u5fd7\u7269\u4ecd\u7136\u60ac\u800c\u672a\u51b3\uff0cPD-L1\u8868\u8fbe\uff0cTMB\u8fd8\u9700\u5176\u4ed6\u6807\u5fd7\u7269\u4ecd\u9700\u63a2\u7d22\u3002<\/div>\n
5. SCLC\u4e2d\u514d\u75ab\u6cbb\u7597\u6b63\u5728\u7531\u540e\u7ebf\u6cbb\u7597\u5411\u7ef4\u6301\u3001\u4e00\u7ebf\u6cbb\u7597\uff0c\u7531\u5355\u836f\u5411\u8054\u5408\u6cbb\u7597\u53d1\u5c55\u5408\u7406\u7684\u6cbb\u7597\u65f6\u673a\uff0c\u6700\u4f73\u7684\u8054\u5408\u7b56\u7565\u662fSCLC\u514d\u75ab\u6cbb\u7597\u5173\u6ce8\u7684\u7126\u70b9\u3002<\/div>\n
6. SCLC\u514d\u75ab\u6cbb\u7597\u63a2\u7d22\u7684\u65b0\u7b56\u7565\uff1aCAR-T\u3001\u9776\u5411NK\u3001\u5de8\u566c\u7ec6\u80de\u3001MDSC\u7684\u836f\u7269\u4ee5\u53ca\u514d\u75ab\u8c03\u8282\u5242\uff0c\u5c06\u4f7fSCLC\u7684\u514d\u75ab\u6cbb\u7597\u66f4\u52a0\u5b8c\u5584\u548c\u9ad8\u6548\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u6731\u6ce2\uff08\u9646\u519b\u533b\u79d1\u5927\u5b66\u65b0\u6865\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u514d\u75ab\u6cbb\u7597\u7684\u5206\u5b50\u6807\u5fd7\u7269\u7814\u7a76\u8fdb\u5c55\u4e0e\u4e34\u5e8a\u5e94\u7528\u300b<\/div>\n
1. \u672a\u6765\u7814\u7a76\u65b9\u54111\uff1a\u591a\u53c2\u6570\u751f\u7269\u6807\u5fd7\u7269\u3002\u5355\u4e00\u751f\u7269\u6807\u5fd7\u7269\u9884\u6d4b\u7597\u6548\u6709\u9650\uff0c\u57fa\u4e8e\u80bf\u7624\u514d\u75ab\u5e94\u7b54\u7684\u590d\u6742\u6027\uff0c\u7efc\u5408\u8003\u8651\u591a\u6b65\u9aa4\u3001\u591a\u53d8\u91cf\u53ef\u80fd\u662f\u672a\u6765\u7814\u7a76\u65b9\u5411\u3002<\/div>\n
2. \u672a\u6765\u7814\u7a76\u65b9\u54112\uff1a\u6db2\u4f53\u6d3b\u68c0\u3002\u80bf\u7624\u7ec6\u80de\u7a81\u53d8\u3001\u57fa\u56e0\u8868\u8fbe\u7624\u5185\u5f02\u8d28\u6027\u548c\u7624\u95f4\u5f02\u8d28\u6027\u662f\u80bf\u7624\u7684\u5171\u540c\u7279\u70b9\uff1b\u80bf\u7624\u7ec6\u80de\u514d\u75ab\u539f\u6027\u53ca\u80bf\u7624\u5fae\u73af\u5883\u666e\u904d\u5b58\u5728\u5f02\u8d28\u6027\u3002<\/div>\n
3. \u57fa\u4e8e\u751f\u7269\u6807\u5fd7\u7269\u7684IO\u6cbb\u7597\u4e34\u5e8a\u8bd5\u9a8c\u5c40\u9650\u6027\uff1a<\/div>\n
1\uff09KN-024\u7814\u7a76\u4e2d\uff0cPD-L1\u9ad8\u8868\u8fbe\u4eba\u7fa4\u4e2dPD-1\u6297\u4f53\u7684ORR\u4e3a45%\uff1bPD-1\u9634\u6027\u60a3\u8005\u4e2d\u670910%\u5de6\u53f3\u7684\u60a3\u8005\u6709\u6548\u3002<\/div>\n
2\uff09CM-026\u7814\u7a76\u4e2d\uff0c\u9ad8TMB\u4eba\u7fa4\u4e2dORR\u4e3a47%\uff1b\u4f4eTMB\u60a3\u8005\u4e2d\u670923%\u60a3\u8005\u6709\u6548\u3002<\/div>\n
4. \u9664\u524d\u77bb\u6027\u5bcc\u96c6\u4eba\u7fa4\u7684\u4e34\u5e8a\u8bd5\u9a8c\u5916\uff0c\u63a2\u7d22\u6027\u6307\u6807\u53ca\u6765\u81ea\u771f\u5b9e\u4e16\u754c\u7684\u5927\u6570\u636e\u5206\u6790\u53ef\u80fd\u662f\u5b9e\u73b0\u80ba\u764c\u7cbe\u51c6\u514d\u75ab\u6cbb\u7597\u7684\u91cd\u8981\u9014\u5f84\u4e4b\u4e00\u3002<\/div>\n
\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0<\/div>\n
\u25c6\u00a0\u6768\u5fd7\u654f\uff08\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u4e2d\u56fd\u80ba\u764c\u514d\u75ab\u6cbb\u7597\u7684\u73b0\u72b6\u3001\u673a\u9047\u4e0e\u6311\u6218\u300b<\/div>\n
1. \u836f\u54c1\u76d1\u7ba1\u5236\u5ea6\u7684\u6539\u9769\u63a8\u8fdb\u56fd\u9645\u65b0\u836f\u5168\u7403\u5316\uff1a2017\u5e746\u6708\u52a0\u5165ICH\uff1bE5\uff081998\uff09\u3001E5 Q&A\uff082006\uff09\u3001E17\uff082017\uff09\u3002<\/div>\n
2. \u5f00\u5c55\u5355\u81c2\u7814\u7a76\u7684\u5f71\u54cd\u56e0\u7d20\uff08\u90e8\u5206\uff09\uff1a\u5145\u5206\u7684\u5386\u53f2\u6570\u636e\uff08\u5bf9\u7167\u6570\u636e\u53ef\u9760\uff09\uff1b\u8bb0\u5f55\u6bcf\u4e00\u4f8b\u60a3\u8005\u7684\u73b0\u6709\u6cbb\u7597\u65b9\u6848\uff08\u786e\u4fdd\u5145\u5206\u6cbb\u7597\uff09\uff1b\u7f13\u89e3\u7387\u8bc4\u4ef7\u7684\u53ef\u9760\u6027\uff08\u65b9\u6cd5\u5b66\uff09\uff1b\u5b89\u5168\u6027\u6570\u636e\u662f\u5426\u8db3\u591f\u7b49\u3002<\/div>\n
3. PD-L1 and\/or TMB\u5747\u4e0d\u662f\u7597\u6548\u9884\u6d4b\u7684\u5b8c\u7f8e\u6307\u6807\u3002<\/div>\n
4. \u514d\u75ab\u5355\u836f\u5728PD-L1 and\/or TMB \u9ad8\u8868\u8fbe\u4eba\u7fa4\u83b7\u76ca\u4ecd\u6709\u9650\uff0c\u514d\u75ab\u8054\u5408\u5316\u7597\u6709\u66f4\u597d\u7684ORR\u548c\u751f\u5b58\u83b7\u76ca\u3002<\/div>\n
5. \u66f4\u591a\u514d\u75ab\u8054\u5408\u6cbb\u7597\u7b56\u7565\uff08IO\u8054\u5408IO\u3001IO\u8054\u5408\u5316\u7597\u3001IO\u8054\u5408\u6297\u8840\u7ba1\u751f\u6210\u6cbb\u7597+\u5316\u7597\u3001IO\u8054\u5408\u6297\u8840\u7ba1\u751f\u6210\u6cbb\u7597\u7b49\uff09\u5728\u4e0d\u65ad\u7684\u4e30\u5bcc\u548c\u63a2\u7d22\u4e4b\u4e2d\u3002<\/div>\n
6. \u4e34\u5e8a\u51b3\u7b56\u4ea6\u5e94\u5c06\u60a3\u8005\u671f\u671b\u8003\u8651\u5728\u5185\u3002<\/div>\n
\u00a0<\/div>\n
CDE \u4e2d\u56fd\u539f\u521b\u6297\u80bf\u7624\u836f\u4e13\u9898\u8bba\u575b<\/div>\n
\uff08\u65f6\u95f4\uff1a9\u670821\u65e5 8:30-12:00\uff09<\/div>\n\n
\n
\"RmFicvQBAkgBzh6zDj6DUh7M7uLEqmu4CqzmUOOC3go2agZUNEyHm5WtibreVQ0cW1skLibdAicvc6TrFIbPt5e0Ew\"\/<\/figure><\/div>\n\n<\/div>\n
<\/div>\n
\u25c6 \u6768\u5fd7\u654f\uff08\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u6297\u80bf\u7624\u65b0\u836f\u5ba1\u8bc4\u5ba1\u6279\u6a21\u5f0f\u6539\u9769\u53ca\u672a\u6765\u65b9\u5411\u300b<\/div>\n
1\uff0e\u5386\u53f2\u7684\u8fdb\u7a0b\uff0c\u4ee5\u7f8e\u56fd\u7684\u836f\u54c1\u76d1\u7ba1\u548c\u8bc4\u4ef7\u4f53\u7cfb\u4f5c\u4e3a\u6848\u4f8b\u8fdb\u884c\u5206\u6790\uff0c\u63d0\u51fa\u76d1\u7ba1\u79d1\u5b66\u7684\u7406\u5ff5\uff0c\u5c06\u79d1\u5b66\u7684\u6700\u65b0\u53d1\u5c55\u6210\u679c\u8f6c\u5165\u836f\u7269\u7814\u53d1\u3002<\/div>\n
2\uff0e\u6211\u56fd\u6297\u764c\u836f\u7814\u53d1\u7684\u60c5\u51b5\uff0c\u81ea\u4e3b\u7814\u53d1\u80fd\u529b\u663e\u8457\u589e\u5f3a\uff0c\u624e\u5806\u73b0\u8c61\u7a81\u51fa\uff0c\u57fa\u7840\u6570\u636e\u4e25\u91cd\u4e0d\u8db3\uff0c\u57fa\u7840\u7814\u7a76\u6709\u5f85\u63d0\u5347\uff0c\u79d1\u5b66\u65b9\u6cd5\u548c\u5de5\u5177\u7684\u7814\u7a76\u4e0e\u5e94\u7528\u6709\u5f85\u589e\u5f3a\u3002<\/div>\n
3\uff0e\u53d1\u5c55\u65b9\u5411\u548c\u8003\u8651\uff0c\u5efa\u7acb\u4ee5\u60a3\u8005\u4e3a\u6838\u5fc3\u7684\u7814\u53d1\u601d\u8def\u4e0e\u6574\u4f53\u8ba1\u5212\uff0c\u7814\u7a76\u548c\u5229\u7528\u79d1\u5b66\u7684\u7814\u53d1\u5de5\u5177\uff0c\u52a0\u5f3a\u5168\u751f\u547d\u5468\u671f\u7684\u7ba1\u7406\u3002<\/div>\n
4\uff0e\u6539\u9769\u52a9\u529b\u521b\u65b0\uff0c\u52a0\u5f3a\u79d1\u5b66\u7814\u7a76\uff0c\u52a0\u5f3a\u591a\u5b66\u79d1\u5408\u4f5c\uff0c\u52a0\u5f3a\u6c9f\u901a\u4ea4\u6d41\u3002<\/div>\n
\u00a0<\/div>\n
<\/div>\n
\u25c6\u00a0\u5468\u660e\uff08CDE\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u5b89\u7f57\u66ff\u5c3c\u4e34\u5e8a\u5ba1\u8bc4\u4e2d\u7684\u8003\u91cf\u300b<\/div>\n
1.\u00a0\u6709\u6548\u6027\u8bc4\u4ef7\u6838\u5fc3\u5173\u6ce8\uff0c\u786e\u8bc1\u6027\u8bd5\u9a8c\u8bbe\u8ba1\u7684\u79d1\u5b66\u6027\uff0c\u8bd5\u9a8c\u6570\u636e\u8d28\u91cf\u7684\u53ef\u9760\u6027\u3002<\/div>\n
2. \u8bc4\u5ba1\u5173\u6ce8\u7684\u5173\u952e\u4e34\u5e8a\u95ee\u9898\uff0c\u6709\u6548\u6027\u7684\u8bc4\u4ef7\u6838\u5fc3\u5173\u6ce8\uff0c\u65b9\u6848\u79d1\u5b66\u6027\u8bc4\u4ef7\uff0c\u5b89\u5168\u6027\u7ba1\u7406\uff0c\u83b7\u76ca\u98ce\u9669\u8bc4\u4ef7\uff0c\u4e0a\u5e02\u540e\u7814\u7a76\u7b49\u3002<\/div>\n
3. NSCLC\u4e2d\u5c0f\u5206\u5b50\u8840\u7ba1\u9776\u5411\u836f\u7269\u7684\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u5e94\u7ed3\u5408\u5f53\u4e0b\u4e34\u5e8a\u5b9e\u8df5\uff0c\u5e76\u5177\u6709\u4e00\u5b9a\u524d\u77bb\u6027\u3002<\/div>\n
4. \u6cbb\u7597\u5b9a\u4f4d\u5e94\u7ed3\u5408\u836f\u7269\u7684\u8d77\u6548\u7279\u70b9\uff0c\u9009\u62e9\u9002\u5408\u7684\u4eba\u7fa4\uff0c\u9009\u62e9\u5408\u9002\u7684\u7814\u53d1\u7b56\u7565\u3002<\/div>\n
5. \u521b\u65b0\u836f\u91cd\u70b9\u5173\u6ce8\u4e0a\u5e02\u540e\u7684\u5b89\u5168\u6027\u7684\u7ba1\u7406\u3002<\/div>\n
6. \u4f01\u4e1a\u540c\u7814\u7a76\u8005\u4e0e\u76d1\u7ba1\u673a\u6784\u5728\u7814\u53d1\u8fc7\u7a0b\u4e2d\u8fdb\u884c\u6709\u6548\u7684\u6c9f\u901a\uff0c\u6c9f\u901a\u4e0e\u4ea4\u6d41\u5728\u524d\uff0c\u7814\u53d1\u4e0e\u8bc4\u5ba1\u5728\u540e\uff0c\u5ba1\u8bc4\u4e0e\u7814\u53d1\u878d\u5408\uff0c\u8fdb\u4e00\u6b65\u4f18\u5316\u8bc4\u5ba1\u6d41\u7a0b\uff0c\u63d0\u9ad8\u7814\u53d1\u4e0e\u8bc4\u5ba1\u6548\u7387\u3002<\/div>\n
<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u5f20\u8679\uff08CDE\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u544b\u55b9\u66ff\u5c3c\u4e34\u5e8a\u5ba1\u8bc4\u4e2d\u7684\u8003\u91cf\u300b<\/div>\n
1. \u5ba1\u8bc4\u8003\u8651\u5305\u62ec\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u501f\u9274\u4e86\u540c\u9002\u5e94\u75c7\u836f\u7269\u7814\u53d1\u7ecf\u9a8c\uff0c\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u5206\u6790\uff0c\u65e2\u5f80\u9776\u5411\u6cbb\u7597\u4e0e\u5426\u5bf9\u7ed3\u679c\u7684\u5f71\u54cd\uff0c\u8bf4\u660e\u4e66\u5b89\u5168\u4fe1\u606f\u7684\u63cf\u8ff0\u7b49\u3002<\/div>\n
2. \u4f9d\u636e\u4ea7\u54c1\u81ea\u8eab\u7279\u70b9\u548c\u73b0\u5b9e\u6761\u4ef6\u5236\u5b9a\u4e34\u5e8a\u7814\u7a76\u8ba1\u5212\u7b56\u7565\u3002<\/div>\n
3. \u65e2\u5f80\u540c\u9002\u5e94\u75c7\u836f\u7269\u7684\u7814\u53d1\u7b56\u7565\u53ca\u6210\u529f\u7ecf\u9a8c\u503c\u5f97\u501f\u9274\u3002<\/div>\n
4. \u9f13\u52b1\u4f01\u4e1a\u5728\u836f\u7269\u4e34\u5e8a\u7814\u53d1\u7684\u5173\u952e\u8282\u70b9\u4e0eCDE\u6c9f\u901a\u4ea4\u6d41\u3002<\/div>\n
<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u590f\u7433\uff08CDE\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u5421\u54af\u66ff\u5c3c\u4e34\u5e8a\u5ba1\u8bc4\u4e2d\u7684\u8003\u91cf\u300b<\/div>\n
1. \u57fa\u4e8e\u2160\/\u2161\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u6709\u6761\u4ef6\u6279\u51c6\u4e0a\u5e02\uff1a\u4e34\u5e8a\u6025\u9700\uff0c\u5177\u6709\u6cbb\u7597\u4f18\u52bf\uff0c\u53ef\u63a7\u7684\u5b89\u5168\u6027\u98ce\u9669\uff0c\u5f00\u5c55\u786e\u8bc1\u6027\u2162\u671f\u7814\u7a76\u3002<\/div>\n
2. \u8ba4\u53ef\u9002\u5e94\u75c7\u5305\u62ec\u65e2\u5f80\u4f7f\u7528\u8fc7\u8d6b\u8d5b\u6c40\u548c\u672a\u4f7f\u7528\u8fc7\u8d6b\u8d5b\u6c40\u7684\u4eba\u7fa4\uff0c\u7533\u529e\u65b9\u9700\u8981\u5f00\u5c55\u4e0a\u5e02\u540e\u7814\u7a76\uff0c\u63d0\u4f9b\u4e0e\u73b0\u6709\u6807\u51c6\u6cbb\u7597\u76f8\u6bd4\uff0c\u542b\u5421\u54af\u66ff\u5c3c\u6cbb\u7597\u65b9\u6848\u5728\u672a\u4f7f\u7528\u8fc7\u8d6b\u8d5b\u6c40\u7684\u4eba\u7fa4\u4e2d\u5177\u6709\u4e34\u5e8a\u4f18\u52bf\u8bc1\u636e\uff0c\u4f5c\u4e3a\u6279\u51c6\u8be5\u9002\u5e94\u75c7\u7684\u6761\u4ef6\u3002<\/div>\n
3. \u5173\u4e8e\u5421\u54af\u66ff\u5c3c\u6574\u4f53\u7814\u53d1\u7b56\u7565\u7684\u601d\u8003\uff0c\u533a\u5206\u65e2\u5f80\u4f7f\u7528\u8fc7\/\u672a\u4f7f\u7528\u8fc7\u8d6b\u8d5b\u6c40\u7684\u4eba\u7fa4\uff0c\u6253\u7834\u5e38\u89c4\u7684\u2160\u2192\u2161\u2192\u2162\u7684\u7814\u53d1\u6a21\u5f0f\uff0c\u66f4\u65e9\u5e03\u5c40\u4e00\u7ebf\u3002<\/div>\n
\u00a0<\/div>\n
<\/div>\n
\u25c6\u00a0\u5f20\u5b81\uff08CDE\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u6297\u80bf\u7624\u521b\u65b0\u836f\u7814\u53d1\u671f\u95f4\u836f\u5b66\u53d8\u66f4\u7684\u5ba1\u8bc4\u8003\u91cf\u300b<\/div>\n
1. \u521b\u65b0\u836f\u836f\u5b66\u7814\u53d1\u7279\u70b9\uff1a\u4e0d\u786e\u5b9a\u6027-\u53d8\u66f4\uff0c\u5bf9\u836f\u7269\u7406\u5316\u6027\u8d28\u7684\u8fdb\u4e00\u6b65\u4e86\u89e3\uff0c\u6ee1\u8db3\u4e34\u5e8a\u7814\u7a76\/\u6cbb\u7597\u9700\u8981\uff0c\u6ee1\u8db3\u653e\u5927\u751f\u4ea7\u7684\u9700\u8981\u3002<\/div>\n
2. \u521b\u65b0\u836f\u836f\u5b66\u8bc4\u4ef7\u601d\u8def\uff1a\u4ee5\u4e34\u5e8a\u8bd5\u9a8c\u65b9\u6848\u4e3a\u6838\u5fc3\uff0c\u4ee5\u4e34\u5e8a\u8bd5\u9a8c\u6837\u54c1\u7684\u5b89\u5168\u6027\u8bc4\u4ef7\u4e3a\u4e3b\u7ebf\uff0c\u4ee5\u4e0d\u540c\u7814\u7a76\u9636\u6bb5\u6837\u54c1\u7684\u53ef\u8854\u63a5\u6027\u4e3a\u6293\u624b\u3002<\/div>\n
3. \u9762\u4e34\u7684\u6311\u6218\uff0c\u57fa\u4e8e\u6709\u9650\u6570\u636e\u7684\u8d28\u91cf\u63a7\u5236\u4f53\u7cfb\u7684\u53ef\u63a5\u53d7\u6027\u3002<\/div>\n
<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u9648\u6653\u5a9b\uff08\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e34\u5e8a\u7814\u7a76\u7ec8\u70b9\u7684\u5ba1\u8bc4\u8003\u8651\u300b<\/div>\n
1. \u6297\u80bf\u7624\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7684\u7ec8\u70b9\u8003\u8651\uff0c\u57fa\u4e8e\u6b7b\u4ea1\u4e8b\u4ef6\u7684\u7ec8\u70b9\u3001\u80bf\u7624\u6d4b\u91cf\u7684\u7ec8\u70b9\u548c\u75c7\u72b6\u8bc4\u4f30\u7684\u7ec8\u70b9\u3002<\/div>\n
2. \u665a\u671f\/\u8f6c\u79fb\u6027NSCLC\u65b0\u836f\u6ce8\u518c\u4e34\u5e8a\u8bd5\u9a8c\u7684\u7ec8\u70b9\u8003\u8651\uff0c\u4ee5\u80bf\u7624\u751f\u7269\u6807\u5fd7\u7269\u5bcc\u96c6\u4eba\u7fa4\u7684\u8bbe\u8ba1\uff0c\u6216\u4e0d\u4ee5\u80bf\u7624\u751f\u7269\u6807\u5fd7\u7269\u5bcc\u96c6\u4eba\u7fa4\u7684\u8bbe\u8ba1\u3002<\/div>\n
3. \u665a\u671f\/\u8f6c\u79fb\u6027NSCLC\u65b0\u836f\u6ce8\u518c\u4e34\u5e8a\u8bd5\u9a8c\u7ec8\u70b9\u8bc4\u4ef7\uff0c\u5305\u62ecOS\u83b7\u76ca\u8003\u8651\u3001PFS\u83b7\u76ca\u8003\u8651\u548cORR\u83b7\u76ca\u8003\u8651\u3002<\/div>\n
4. \u4e0d\u540c\u7684\u75be\u75c5\u548c\u60c5\u51b5\u4e0b\u9002\u7528\u4e0d\u540c\u7684\u7ec8\u70b9\uff0c\u8003\u8651\u75be\u75c5\u7684\u7c7b\u578b\u3001\u83b7\u76ca\u7684\u7a0b\u5ea6\u3001\u5f53\u524d\u6cbb\u7597\u3001\u4e34\u5e8a\u7684\u9700\u6c42\u548c\u53ef\u64cd\u4f5c\u6027\u3002<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
\u591a\u5b66\u79d1\u534f\u4f5c\u80cc\u666f\u4e0b\u80c3\u764c\u8bca\u6cbb\u5b9e\u8df5\u4e0e\u63a2\u7d22\u00a0<\/div>\n
\uff08\u65f6\u95f4\uff1a9\u670821\u65e5 8:30-12:00\uff09<\/div>\n
<\/div>\n
<\/div>\n
\u25c6\u00a0\u5f90\u745e\u534e \u6559\u6388\uff08\u4e2d\u5c71\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u80c3\u764c\u514d\u75ab\u6cbb\u7597\uff1a\u73b0\u72b6\u00b7\u53cd\u601d\u00b7\u521b\u65b0\u300b<\/div>\n
1. \u6211\u56fd\u662f\u80c3\u764c\u9ad8\u53d1\u56fd\u5bb6\uff0c\u5360\u5168\u7403\u65b0\u53d1\u75c5\u4f8b\u768447%\uff0c\u80c3\u764c\u53d1\u75c5\u7387\u5360\u6211\u56fd\u6076\u6027\u80bf\u7624\u7b2c\u4e8c\u4f4d\u3002<\/div>\n
2. \u665a\u671f\u80c3\u764c\u6cbb\u7597\u73b0\u72b6\uff0c\u4f20\u7edf\u5316\u7597\u5df2\u9762\u4e34\u74f6\u9888\uff0c\u666e\u901a\u9776\u5411\u6cbb\u7597\u8fdb\u5c55\u7f13\u6162\uff0c\u8054\u5408\u5316\u7597\/\u5176\u4ed6\u6cbb\u7597\u53ef\u80fd\u662f\u7a81\u7834\u3002<\/div>\n
3. \u6211\u56fd\u539f\u7814\u514d\u75ab\u6cbb\u7597\u836f\u7269\u5728\u80c3\u764c\u65b9\u9762\uff0c\u4e8e\u56fd\u9645\u4e0a\u6682\u65f6\u5904\u4e8e\u8ddf\u8dd1\u5730\u4f4d\uff0c\u80c3\u764c\u514d\u75ab\u6cbb\u7597\u65b9\u6848\u7684\u4f18\u5316\u7814\u7a76\u6210\u4e3a2018\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\u9879\u76ee\u3002<\/div>\n
4. \u672a\u7ecf\u7b5b\u9009\u7684\u4eba\u7fa4\uff0c\u540e\u7ebf\u6cbb\u7597\u5355\u836f\u6709\u6548\uff0c\u4f46\u6709\u6548\u7387\u4e0d\u9ad8\uff0c\u5229\u7528\u751f\u7269\u6807\u5fd7\u7269\uff0c\u7b5b\u9009\u6f5c\u5728\u6709\u6548\u4eba\u7fa4\uff0c\u5408\u7406\u8054\u5408\u7528\u5176\u4ed6\u6cbb\u7597\uff0c\u63d0\u9ad8\u7597\u6548\u3002<\/div>\n
\u00a0<\/div>\n
<\/div>\n
\u25c6\u00a0\u6c88\u7433 \u6559\u6388\uff08\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u80c3\u764c\u836f\u7269\u6cbb\u7597\u7597\u6548\u7cbe\u51c6\u9884\u6d4b\u548c\u8bc4\u4ef7\u8fdb\u5c55\u300b<\/div>\n
1. \u80c3\u764c\u5177\u6709\u7a7a\u95f4\u5f02\u8d28\u6027\uff0c\u591a\u79cd\u80bf\u7624\u9a71\u52a8\u673a\u5236\uff0c\u4e2a\u4f53\u5dee\u5f02\u5927\uff0c\u4e0d\u540c\u60a3\u8005\u5bf9\u6cbb\u7597\u7597\u6548\u53cd\u5e94\u5177\u6709\u660e\u663e\u5dee\u5f02\u3002<\/div>\n
2. \u80c3\u764c\u5177\u6709\u65f6\u95f4\u5f02\u8d28\u6027\uff0c\u5feb\u901f\u53d1\u751f\u8010\u836f\uff0c\u8010\u836f\u673a\u5236\u53d1\u751f\u52a8\u6001\u6f14\u53d8\uff0c\u9700\u8981\u5b9e\u65f6\u52a8\u6001\u76d1\u6d4b\u836f\u7269\u7597\u6548\u3002<\/div>\n
3. \u80c3\u764c\u5177\u6709\u53ca\u5176\u590d\u6742\u7684\u8f6c\u79fb\u9014\u5f84\uff0c\u4e34\u5e8a\u4e2d\u975e\u5e38\u6709\u9650\u7684\u9776\u5411\u6cbb\u7597\u53ca\u514d\u75ab\u6cbb\u7597\u7b56\u7565\u3002<\/div>\n
4. \u5e94\u591a\u6c34\u5e73\u3001\u591a\u7ec4\u5b66\u6cbb\u7597\u7597\u6548\u8bc4\u4f30\u624b\u6bb5\u7684\u7efc\u5408\u6574\u5408\u53ca\u5e94\u7528\u3002<\/div>\n
5. \u4e9f\u5f85\u66f4\u6709\u6548\u7684\u514d\u75ab\u6cbb\u7597\u7597\u6548\u8bc4\u4f30\u7b56\u7565\u7684\u4e34\u5e8a\u5b9e\u8df5\u5e94\u7528\u3002<\/div>\n
<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u5f20\u8273\u6865 \u6559\u6388\uff08\u54c8\u5c14\u6ee8\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u665a\u671f\u80c3\u764c\u4e00\u7ebf\u6cbb\u7597\u5931\u8d25\u540e\u7684\u6cbb\u7597\u73b0\u72b6\u4e0e\u524d\u666f\u300b<\/div>\n
1. \u4e00\u7ebf\u6cbb\u7597\u5931\u8d25\u540e\u7684\u5316\u7597\u7b56\u7565\uff0c\u4e8c\u7ebf\u9009\u62e9\u5355\u836f\uff08\u7d2b\u6749\u9187\/\u591a\u897f\u4ed6\u8d5b\/\u4f0a\u7acb\u66ff\u5eb7\uff09\u4e3a\u4e3b\uff0c\u4e09\u7ebf\u5316\u7597\u83b7\u76ca\u4e0d\u660e\u786e\u3002<\/div>\n
2. \u9776\u5411\u6cbb\u7597\u7b56\u7565\uff0cHER2\u9633\u6027\u75c5\u4eba\u4e00\u7ebf\u672a\u7528\u8fc7\u8d6b\u8d5b\u6c40\uff0c\u4e8c\u7ebf\u53ef\u4ee5\u8054\u5408\u5316\u7597\u4f7f\u7528\uff1b\u4e8c\u7ebf\u4f7f\u7528NCCN\u96f7\u83ab\u82a6\u5355\u6297\uff0c\u4e2d\u56fd\u6b63\u5728\u8fdb\u884c\u4e09\u671f\u7814\u7a76\uff1b\u4e09\u7ebf\u6cbb\u7597\u53ef\u4f7f\u7528\u56fd\u5185\u7684\u963f\u5e15\u66ff\u5c3c\u3002<\/div>\n
3. \u76ee\u524d\u514d\u75ab\u6cbb\u7597\u5728\u80c3\u764c\u7684\u6cbb\u7597\u6548\u679c\u8f83\u4f4e\uff0c\u5355\u836f\u6709\u6548\u7387\u4ec5\u4e3a10-15%\uff0c\u7597\u6548\u6807\u5fd7\u7269\u5c1a\u4e0d\u660e\u786e\u3002<\/div>\n
4. \u80c3\u764c\u514d\u75ab\u6cbb\u7597\u88ab\u9ad8\u5ea6\u671f\u5f85\uff0c\u8054\u5408\u6cbb\u7597\u662f\u589e\u5f3a\u514d\u75ab\u7597\u6548\u7684\u65b9\u5411\uff0c\u57fa\u4e8e\u751f\u7269\u6807\u8bb0\u7269\u7684\u4e2a\u4f53\u5316\u6cbb\u7597\u662f\u7b56\u7565\u3002<\/div>\n
<\/div>\n
\u00a0<\/div>\n
<\/div>\n
\u80bf\u7624\u751f\u7269\u6807\u5fd7\u7269\u4e13\u573a<\/div>\n
<\/div>\n
\uff08\u65f6\u95f4\uff1a9\u670820\u65e5 14:30-17:00\uff09<\/div>\n
<\/div>\n
\n\n
\n
\"RmFicvQBAkgBzh6zDj6DUh7M7uLEqmu4ClkPxy9GRrMI3qFnsTpzVkjNQNKPnfslZxW2ZzkuU3xDibgs6Zbicamlg\"\/<\/figure><\/div>\n\n
\u25c6\u00a0\u9a6c\u519b\uff08\u54c8\u5c14\u6ee8\u8840\u6db2\u75c5\u80bf\u7624\u7814\u7a76\u6240\uff09<\/div>\n
\u62a5\u544a\u9898\u76ee\uff1a\u300a\u6076\u6027\u6dcb\u5df4\u7624\u8bca\u65ad\u53ca\u514d\u75ab\u6cbb\u7597\u7684\u8fdb\u5c55\u300b<\/div>\n
1. \u73b0\u72b6\uff1a\u5168\u56fd\u80bf\u7624\u7b49\u7ea7\u5730\u533a\u6dcb\u5df4\u7624\u7684\u53d1\u75c5\u7387\u4e3a6.68\/10\u4e07\uff0c\u4e2d\u56fd\u4eba\u53e3\u6807\u51c6\u5316\u7387\u4e3a3.75\/10\u4e07\uff1b\u540c\u671f\u6dcb\u5df4\u7624\u6b7b\u4ea1\u7387\u4e3a3.75\/10\u4e07\uff0c\u4e2d\u56fd\u4eba\u53e3\u6807\u51c6\u5316\u73871.86\/10\u4e07\u3002<\/div>\n
2. CAR-T\u7ec6\u80de\u514d\u75ab\u6cbb\u7597B\u7ec6\u80de\u6076\u6027\u80bf\u7624\uff0c\u5728ALL\u3001CLL\u3001NHL\u4e2d\u83b7\u5f97\u4e86\u9ad8\u7f13\u89e3\u7387\u3002<\/div>\n
3. \u56fd\u5185\u7684\u4f01\u4e1a\u5bb9\u6613\u8702\u62e5\u800c\u4e0a\uff0c\u4e0d\u8003\u8651\u72ec\u7279\u6027\u548c\u5dee\u5f02\u5316\uff0c\u5bfc\u81f4\u5e02\u573a\u88ab\u5206\u5272\uff0c\u90fd\u8d5a\u4e0d\u5230\u94b1\uff0c\u751a\u81f3\u51fa\u73b0\u52a3\u5e01\u9a71\u9010\u826f\u5e01\u3002\u591a\u5bb6\u516c\u53f8\u6b63\u5728\u5bfb\u6c42FDA\u6279\u51c6CD19\u9776\u5411\u7ec6\u80de\u6cbb\u7597\u3002<\/div>\n
4. \u6cbb\u7597\u590d\u53d1\u96be\u6cbbDLBCL\u7684\u7f13\u89e3\u7387\u4f18\u4e8e\u4f20\u7edf\u6807\u51c6\u6cbb\u7597\u7684\u7ed3\u679cSCHOLAR1 trial\uff088% CR rate\uff09\u3002<\/div>\n
5. \u5c06\u4e2a\u4f53\u5316\u7ec6\u80de\u6cbb\u7597\u5f15\u5165\u4e3b\u6d41\u7684\u6297\u80bf\u7624\u6cbb\u7597\uff0c\u76ee\u524d\u6709\u56f0\u96be\uff1a\u751f\u4ea7-\u9700\u8981\u53ef\u9760\u7684\u5feb\u901f\u5468\u671f\uff1b\u5206\u5e03-\u4e16\u754c\u8303\u56f4\uff1b\u6cbb\u7597-\u521d\u59cb\u6cbb\u7597\u9700\u8981\u5728\u79fb\u690d\u75c5\u623f\u4e2d\u8fdb\u884c\uff1b\u5904\u7406\u6709\u53ef\u80fd\u7684\u4e25\u91cd\u6bd2\u6027\u53cd\u5e94\u3002<\/div>\n
6. \u5bf9\u4e8e\u96be\u6cbb\u6027\u7684\u60a3\u8005\u6765\u8bf4\u8fd9\u53ef\u80fd\u662f\u4e00\u79cd\u65b0\u7684\u7597\u6cd5\uff0c\u5e76\u4e14\u533b\u751f\u4f1a\u8d8a\u6765\u8d8a\u719f\u6089\u5b83\u3002<\/div>\n
7. \u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u8054\u5408\u9776\u5411\u6cbb\u7597\u53ef\u80fd\u6210\u4e3a\u672a\u6765\u7684\u65b0\u8d8b\u52bf\uff0c\u6709\u671b\u4e3a\u6dcb\u5df4\u7624\u60a3\u8005\u63d0\u4f9b\u4e00\u7c7b\u9ad8\u6548\u3001\u4f4e\u6bd2\u6027\u7684\u65b9\u6848\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u5f20\u7eea\u8d85\uff08\u5e7f\u4e1c\u7701\u4eba\u6c11\u533b\u9662\uff09<\/div>\n
\u6f14\u8bb2\u9898\u76ee\uff1a\u300a\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u8010\u836f\u4e0e\u8fdb\u5316\u76f8\u5173\u5206\u5b50\u6807\u5fd7\u7269\u300b<\/div>\n
1. \u6076\u6027\u80bf\u7624\u4e2d\u201c\u7ec6\u80de\u6216\u5206\u5b50\u5f02\u8d28\u6027\u201d\u5e7f\u6cdb\u5b58\u5728\uff0c\u4e14\u5b58\u5728\u52a8\u6001\u65f6\u7a7a\u5206\u5e03\u3002<\/div>\n
2. \u5728ICI\u4e2d\uff0c\u201c\u514d\u75ab\u7f16\u8f91\u201d\u59cb\u7ec8\u5b58\u5728\uff0cTMB\u3001\u65b0\u6297\u539f\u3001TCR\u3001PD-L1\u7b49\u53ef\u80fd\u53d1\u751f\u52a8\u6001\u5f02\u8d28\u6027\u53d8\u5316\uff0c\u4ece\u800c\u5f71\u54cd\u7597\u6548\u3002<\/div>\n
3. \u514d\u75ab\u6cbb\u7597\u8010\u836f\u5b58\u5728\u590d\u6742\u673a\u5236\uff08NeoAg\u3001HLA\u3001TIL\/TCR\u7b49\uff09\u3002<\/div>\n
4. \u9700\u8981\u66f4\u591a\u7ec6\u8282\u7814\u7a76\u4ece\u8fdb\u5316\u89d2\u5ea6\u9610\u8ff0\u8010\u836f\u673a\u5236\uff0c\u5982\u6297\u539f\u8eab\u4efd\uff08KRAS K12D\u3001CD19truncation\u3001NeoAg LOH\u7b49\uff09\u3002\u8f6c\u5316\u7814\u7a76\u6709\u52a9\u4e8e\u9610\u660e\u673a\u5236\u5e76\u5bfb\u627e\u5bf9\u7b56\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u5218\u6bc5\uff08\u4e2d\u56fd\u4eba\u6c11\u89e3\u653e\u519b\u7b2c307\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u9898\u76ee\uff1a\u300a\u80bf\u7624\u5faa\u73af\u6807\u5fd7\u7269\u4e0e\u75be\u75c5\u8fdb\u5316\u7684\u5173\u7cfb\u53ca\u5e94\u7528\u300b<\/div>\n
1. ctDNA\u4e34\u5e8a\u5e94\u7528\u7684\u6ce8\u610f\u4e8b\u9879\uff1a<\/div>\n
1\uff09ctDNA\u68c0\u6d4b\u6700\u9002\u5408\u7528\u8840\u6d46\uff08\u91c7\u7528\u53ef\u8fdb\u884c\u7ec6\u80de\u56fa\u5b9a\u7684\u7ba1\u5b50\u6216EDTA\u7ba1\u91c7\u8840\uff09\u6765\u5b8c\u6210\uff1b<\/div>\n
2\uff09\u6709\u4e9bctDNA\u68c0\u6d4b\u5728\u67d0\u4e9b\u665a\u671f\u764c\u75c7\u7684\u4e34\u5e8a\u7528\u9014\u5df2\u7ecf\u5f97\u5230\u4e86\u5145\u5206\u8bc1\u5b9e\uff0c\u4f46\u5728\u591a\u6570\u665a\u671f\u764c\u75c7\u4e2d\u5374\u8bc1\u636e\u4e0d\u8db3\uff1b<\/div>\n
3\uff09ctDNA\u4e0e\u7ec4\u7ec7\u6807\u672c\u7684\u68c0\u6d4b\u7ed3\u679c\u4f1a\u51fa\u73b0\u4e0d\u4e00\u81f4\uff0c\u9700\u8981\u901a\u8fc7\u7ec4\u7ec7\u5b66\u68c0\u6d4b\u6765\u786e\u8ba4ctDNA\u6ca1\u6709\u68c0\u6d4b\u5230\u7684\u539f\u56e0\uff1b<\/div>\n
4\uff09ctDNA\u5728\u65e9\u671f\u764c\u75c7\uff0c\u6cbb\u7597\u68c0\u6d4b\u6216\u6b8b\u7559\u75be\u75c5\u68c0\u6d4b\u7b49\u65b9\u9762\u6ca1\u6709\u4e34\u5e8a\u5e94\u7528\u7684\u8bc1\u636e\u6216\u8005\u8f83\u5c11\u6709\u4e34\u5e8a\u9a8c\u8bc1\u7684\u8bc1\u636e\uff1b<\/div>\n
5\uff09\u6ca1\u6709\u8bc1\u636e\u63d0\u793actDNA\u68c0\u6d4b\u53ef\u4ee5\u7528\u4e8e\u764c\u75c7\u7b5b\u67e5\uff0c\u4e34\u5e8a\u8bd5\u9a8c\u9664\u5916\u3002<\/div>\n
2. CTC\u68c0\u6d4b\u6280\u672f\u8be5\u5982\u4f55\u66f4\u597d\u7684\u6ee1\u8db3\u4e34\u5e8a\u6cbb\u7597\u7684\u9700\u6c42\uff1a<\/div>\n
1\uff09\u66f4\u9ad8\u7684\u5bcc\u96c6\u6548\u7387\uff1a\u53ef\u80fd\u9700\u8981\u65b0\u9896\u72ec\u7279\u7684\u7b56\u7565\u6216\u8005\u51e0\u79cd\u7b56\u7565\u7684\u8054\u5408\uff1b<\/div>\n
2\uff09\u7279\u5f02\u7684\u9a8c\u8bc1\u7b56\u7565\uff1a\u4ece\u529f\u80fd\u548c\u8868\u578b\u4e0a\u6b63\u5f0f\u76ee\u7684\u7ec6\u80de\u5c31\u662f\u771f\u6b63\u7684CTC\uff1b<\/div>\n
3\uff09\u51c6\u786e\u6027\u548c\u91cd\u590d\u6027\uff1a\u5c3d\u91cf\u91c7\u7528\u81ea\u52a8\u5316\u4eea\u5668\uff0c\u907f\u514d\u4eba\u4e3a\u5f71\u54cd\u56e0\u7d20\u5e72\u6270\uff1b<\/div>\n
4\uff09\u53ef\u64cd\u4f5c\u548c\u63a8\u5e7f\u6027\uff1a\u7b80\u5355\u5b9e\u7528\u3001\u786c\u4ef6\u548c\u6280\u672f\u4eba\u5458\u8981\u6c42\u3001\u4ef7\u683c\u95ee\u9898\u7b49\uff1b<\/div>\n
5\uff09\u5145\u5206\u8003\u8651\u5f02\u8d28\u6027\uff1a\u4e0d\u540c\u4e9a\u578bCTC\u7684\u4e34\u5e8a\u610f\u4e49\u4e0d\u540c\uff0c\u9700\u8981\u533a\u522b\u5bf9\u5f85\uff1b<\/div>\n
6\uff09\u5faa\u8bc1\u533b\u5b66\u7684\u8bc1\u636e\uff1a\u4efb\u4f55\u6280\u672f\u90fd\u5e94\u4e8b\u5148\u7ecf\u8fc7\u4e25\u8c28\u7684\u4e34\u5e8a\u8bd5\u9a8c\u6765\u8bc1\u5b9e\u4e00\u5207\u4ee5\u89e3\u51b3\u95ee\u9898\u4e3a\u6839\u672c\u51fa\u53d1\u70b9\u3002<\/div>\n
\u00a0<\/div>\n
2\u536b\u661f\u4f1a<\/div>\n
\u25c6 \u5143\u7801\u57fa\u56e0\uff1a\u7cbe\u51c6\u533b\u7597\u7684\u9053\u3001\u672f\u3001\u6cd5<\/div>\n\n
\n
\"?wx_fmt=jpeg\"\/<\/figure><\/div>\n\n<\/div>\n
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\u7f16\u8005\uff1aClare\/\u8292\u679c\/Eric\/Candice\u00a0 \u00a0\u6821\u5bf9\uff1a\u5c18\u7070\u00a0 \u00a0\u5ba1\u6838\uff1aMark<\/div>\n
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\u00a0 \u57fa\u56e0\u6167\u62db\u8058\u00a0\u00a0<\/div>\n
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\u65b0\u5a92\u4f53\u7f16\u8f91\u3001\u884c\u4e1a\u5206\u6790\u5e08<\/div>\n
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\u00a0<\/div>\n
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\u300a2018-2019\u5e74\u4e2d\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b<\/a><\/div>\n
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