\n![\"RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg.gif\")
<\/figure><\/div>\n\n<\/div>\n
<\/figure><\/div>\n\n<\/div>\n<\/div>\n
\u5173\u952e\u8bcd\/2018CSCO \u4f1a\u8bae\u7b14\u8bb0 \u00a0 \u00a0\u6587\/\u57fa\u56e0\u6167<\/div>\n
<\/div>\n
2018\u5e749\u670822\u65e5\uff0c\u7b2c\u4e8c\u5341\u4e00\u5c4a\u5168\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u5927\u4f1a\u66a82018\u5e74\u4e2d\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a\uff08CSCO\uff09\u5b66\u672f\u5e74\u4f1a\u8fce\u6765\u7b2c\u4e09\u5929\u5373\u6700\u540e\u4e00\u5929\u65e5\u7a0b\uff0c\u81f3\u6b64\u57283\u4e07\u591a\u89c2\u4f17\u53c2\u4e0e\u4e0b\uff0c75\u4e2a\u5b66\u672f\u4e13\u573a\u300190\u573a\u536b\u661f\u4f1a\u5706\u6ee1\u7ed3\u675f\u3002\u57fa\u56e0\u6167\u4e8e\u5927\u4f1a\u73b0\u573a\u6574\u7406\u5e76\u7b2c\u4e00\u65f6\u95f4\u62a5\u9053\u9996\u65e5\uff08\u8be6\u60c5<\/a>\uff09\u53ca\u7b2c\u4e8c\u65e5\u7b14\u8bb0\uff08\u8be6\u60c5<\/a>\uff09\uff0c\u4ee5\u4e0b\u662f\u7b14\u8bb0\u56de\u987e\u53ca\u5927\u4f1a\u7b2c\u4e09\u65e5\u91cd\u8981\u5b66\u672f\u4e13\u573a\u7b14\u8bb0\uff0c\u6b22\u8fce\u7559\u8a00\u8ba8\u8bba\u3002<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
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19\u670820\u65e5-21\u65e5\u5e72\u8d27\u56de\u987e<\/div>\n
<\/div>\n
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\uff08\u70b9\u51fb\u5bf9\u5e94\u56fe\u7247\u56de\u987e\u9996\u65e5\/\u7b2c\u4e8c\u65e5\u7b14\u8bb0\uff09<\/div>\n
<\/div>\n
<\/div>\n
\u9996\u65e5\u4e13\u573a\u7b14\u8bb0\u70b9\u51fb \u2193<\/div>\n
<\/p>\n\n
\n![\"RmFicvQBAkgDtjXsEYibX7SY8zvu0kuWI9460WBuzgZzUgficJEbACW60q81vMTsXHnwNN8zd3icXMrbLTrnSBiaMiaw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDtjXsEYibX7SY8zvu0kuWI9460WBuzgZzUgficJEbACW60q81vMTsXHnwNN8zd3icXMrbLTrnSBiaMiaw.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n<\/a><\/div>\n
<\/p>\n\n
\n![\"RmFicvQBAkgDtjXsEYibX7SY8zvu0kuWI9etpIiblhxEsNjDUyfyEvUt7YEJf53qDg8Exuibu3EXeJM4Xyobw9RjbA\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDtjXsEYibX7SY8zvu0kuWI9etpIiblhxEsNjDUyfyEvUt7YEJf53qDg8Exuibu3EXeJM4Xyobw9RjbA.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n<\/a><\/div>\n
\u2191 \u7b2c\u4e8c\u65e5\u4e13\u573a\u7b14\u8bb0\u70b9\u51fb<\/div>\n
<\/div>\n
<\/div>\n
29\u670822\u65e5\u5b66\u672f\u4e13\u573a<\/div>\n
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\u521b\u65b0\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u4e13\u573a 2<\/div>\n
<\/div>\n
<\/div>\n
\uff08\u65f6\u95f4\uff1a9\u670822\u65e5 8:30-12:00\uff09<\/div>\n
<\/div>\n
\n\n
\n![\"?wx_fmt=png\"\/](\"https:\/\/mmbiz.qpic.cn\/mmbiz_png\/RmFicvQBAkgDtjXsEYibX7SY8zvu0kuWI9doVtib1ibNofvrTtqwuIxynWZ3O5lWiaic02uMP2lmoIof5wSaI6ibY2Y8Q\/?wx_fmt=png\")
<\/figure><\/div>\n\n
\u25c6\u00a0\u6731\u519b\uff08\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300aZanubrutinib, \u4e00\u4e2a\u9ad8\u9009\u62e9\u6027 BTK \u6291\u5236\u5242\u5728\u4e2d\u56fd\u590d\u53d1\/\u96be\u6cbbB\u7ec6\u80de\u6dcb\u5df4\u7624\u60a3\u8005\u4e2d\u76841\u671f\u4e34\u5e8a\u7814\u7a76\u521d\u6b65\u62a5\u544a\u300b<\/div>\n
1.\u00a0 \u5728\u5b89\u5168\u6027\u8bc4\u4f30\u9636\u6bb5\uff08\u7b2c1\u9636\u6bb5\uff09\u672a\u89c1\u5242\u91cf\u9650\u5236\u6027\u6bd2\u6027\u3002<\/div>\n
2.\u00a0 \u672a\u89c1\u975e\u9884\u671f\u7684\u5b89\u5168\u6027\u4fe1\u53f7\u3002Zanubrutinib\u5728\u4e2d\u56fdB\u7ec6\u80de\u6076\u6027\u80bf\u7624\u60a3\u8005\u4e2d\u8868\u73b0\u51fa\u826f\u597d\u7684\u5b89\u5168\u6027\u548c\u8010\u53d7\u6027\u3002<\/div>\n
3.\u00a0 \u836f\u4ee3\u52a8\u529b\u5b66\u7814\u7a76\u7684\u521d\u6b65\u7ed3\u679c\u8868\u660e\u3002\u4e2d\u56fd\u548c\u975e\u4e2d\u56fd\u53d7\u8bd5\u8005\u7684\u836f\u4ee3\u52a8\u529b\u5b66\u7279\u5f81\u6ca1\u6709\u663e\u8457\u5dee\u5f02\u3002<\/div>\n
4.\u00a0 \u6839\u636e\u5b89\u5168\u6027\u3001\u8010\u53d7\u6027\u3001\u836f\u4ee3\u52a8\u529b\u5b66\u548c\u7597\u6548\u6570\u636e\uff0c\u5728\u4e2d\u56fdII\u671f\u7814\u7a76\u4e2d\u4f7f\u7528\u63a8\u8350\u5242\u91cf160mg BID\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u6c5f\u6cfd\u98de\uff08\u89e3\u653e\u519b307\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u65b0\u578b\u8868\u89c2\u9057\u4f20\u5b66\u6291\u5236\u5242\u897f\u8fbe\u672c\u80fa\u6cbb\u7597\u6fc0\u7d20\u53d7\u4f53\u9633\u6027\u665a\u671f\u4e73\u817a\u764c\u7684\u63a2\u7d22\u6027\u7814\u7a76\u300b<\/div>\n
1.\u00a0 \u7814\u7a76\u521d\u6b65\u7ed3\u679c\uff1a<\/div>\n
1)\u00a0\u00a0\u4e0e\u4f9d\u897f\u7f8e\u5766\u5355\u836f\u76f8\u6bd4\uff0c\u897f\u8fbe\u672c\u80fa\u8054\u5408\u4f53\u897f\u7f8e\u5766\u53ef\u663e\u8457\u5ef6\u957f\u60a3\u8005\u65e0\u75be\u75c5\u8fdb\u5c55\u751f\u5b58\u671f\uff0c\u63d0\u9ad8\u80bf\u7624\u5ba2\u89c2\u7f13\u89e3\u7387\u548c\u4e34\u5e8a\u83b7\u76ca\u7387\uff1b<\/div>\n
2)\u00a0\u00a0\u8054\u5408\u65b9\u6848\u4e0b\u7684\u6bd2\u6027\u53cd\u5e94\uff0c\u4e0e\u897f\u8fbe\u672c\u80fa\u5355\u836f\u4e34\u5e8a\u8bd5\u9a8c\u53ca\u4e0a\u5e02\u540e\u7528\u836f\u89c2\u5bdf\u7ed3\u679c\u76f8\u4f3c\uff0c\u5927\u90e8\u5206\u60a3\u8005\u53ef\u4ee5\u8010\u53d7\uff0c\u5b89\u5168\u6027\u53ef\u63a7\u3002<\/div>\n
3)\u00a0\u00a0\u5168\u7403\u9996\u6b21\u901a\u8fc7\u786e\u8bc1\u6027\u4e34\u5e8a\u8bd5\u9a8c\u663e\u793aHDAC\u6291\u5236\u5242\u5728\u665a\u671f\u5b9e\u4f53\u7624\u60a3\u8005\u7684\u7efc\u5408\u83b7\u76ca\uff0c\u897f\u8fbe\u672c\u80fa\u8054\u5408\u4f53\u897f\u7f8e\u5766\u65b9\u6848\u6709\u671b\u4e3a\u6fc0\u7d20\u53d7\u4f53\u9633\u6027\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u63d0\u4f9b\u4e00\u79cd\u65b0\u7684\u6cbb\u7597\u65b9\u5f0f\uff0c<\/div>\n
2.\u00a0 \u7814\u7a76\u610f\u4e49\uff1a<\/div>\n
1)\u00a0\u00a0\u6fc0\u7d20\u53d7\u4f53\u9633\u6027\u665a\u671f\u4e73\u817a\u764c\u60a3\u8005\u589e\u52a0\u4e00\u79cd\u65b0\u7684\u6cbb\u7597\u65b9\u5f0f(\u897f\u8fbe\u672c\u80fa\u8054\u5408\u5185\u5206\u6ccc\u6cbb\u7597)\u3002<\/div>\n
2)\u00a0\u00a0\u6570\u636e\u6e05\u7406\uff0c\u63d0\u4ea4\u7533\u8bf7\uff0c\u7533\u8bf7\u65b0\u9002\u5e94\u75c7\u3002<\/div>\n
3)\u00a0\u00a0\u521b\u65b0\u836f\u7269\u6210\u529f\u7684\u4e34\u5e8a\u7814\u7a76\uff0c\u6ee1\u8db3\u5e02\u573a\u9700\u6c42\u3002<\/div>\n
4)\u00a0\u00a0\u81ea\u4e3b\u7814\u53d1\uff0c\u81ea\u4e3b\u4ea7\u6743\uff0c\u521b\u65b0\u8bbe\u8ba1\uff0c\u5f71\u54cd\u6307\u5357\uff0c\u6539\u53d8\u5b9e\u8df5\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u5f90\u5175\u6cb3\uff08\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300aExteNET\u7814\u7a76\u4e9a\u6d32\u53ca\u4e2d\u56fd\u60a3\u8005\u6570\u636e\u5206\u6790\u300b<\/div>\n
1.\u00a0 \u6765\u90a3\u66ff\u5c3c\u662f\u5168\u7403\u552f\u4e00\u7528\u4e8eHER2\u9633\u6027\u4e73\u817a\u764c\u5f3a\u5316\u8f85\u52a9\u6cbb\u7597\u7684\u521b\u65b0\u5c0f\u5206\u5b50TKI\uff0c\u663e\u8457\u964d\u4f4e\u4e2d\u56fd\u65e9\u671fHER2\u9633\u6027\u4e73\u817a\u764c\u60a3\u8005\u590d\u53d1\u98ce\u966940%\u3002\u4e2d\u56fd\u548c\u4e9a\u6d32\u961f\u5217\u4e2d5\u5e74iDFS\u5206\u6790\u7684\u7ed3\u679c\u4e0e\u5168\u7403\u7ed3\u679c\u4e00\u81f4\u3002<\/div>\n
2. \u4e2d\u56fd\u548c\u4e9a\u6d32\u961f\u5217AE\u7279\u5f81\u4e0e\u5168\u7403\u4e00\u81f4\uff0c\u6765\u90a3\u66ff\u5c3c\u76f8\u5173\u6027\u8179\u6cfb\u53ef\u7ba1\u7406\u3002<\/div>\n
3. \u9996\u6b21\u6c47\u603b\u5206\u6790\u7ed3\u679c\u62ab\u9732\uff1b\u4e2d\u56fd\u3001\u4e9a\u6d32\u548c\u5168\u7403\u7684\u5173\u952e\u836f\u4ee3\u52a8\u529b\u5b66\u53c2\u6570\u76f8\u4f3c\u3002\u6765\u90a3\u66ff\u5c3c\u5bf9\u4eba\u79cd\u4e0d\u654f\u611f\uff0c\u53ef\u4ee5\u5c063004\u7814\u7a76\u5916\u63a8\u5230\u5176\u4ed6\u79cd\u65cf\u548c\u5730\u533a\uff0c\u7279\u522b\u662f\u4e2d\u56fd\u60a3\u8005\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u9a6c\u519b\u6559\u6388\uff08\u54c8\u5c14\u6ee8\u8840\u6db2\u75c5\u80bf\u7624\u7814\u7a76\u6240\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300aNGS\u6280\u672f\u68c0\u6d4bANL\u5fae\u5c0f\u6b8b\u7559\u75c5\uff08MRD\uff09\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\u300b<\/div>\n
1. ADC\u836f\u7269\u80fd\u591f\u5c06\u5355\u514b\u9686\u6297\u4f53\u4e0e\u5c0f\u5206\u5b50\u5316\u5408\u7269\u7684\u4f18\u52bf\u7ed3\u5408\uff0c\u662f\u6781\u5177\u6f5c\u529b\u7684\u6297\u80bf\u7624\u836f\u7269\u3002<\/div>\n
2. HER2-ADC\u836f\u7269\u53ef\u80fd\u6210\u4e3a\u6cbb\u7597\u5c3f\u8def\u4e0a\u76ae\u764c\u7684\u9009\u62e9\u3002<\/div>\n
3. \u521d\u6b65\u6570\u636e\u7ed3\u679c\u663e\u793a\uff0cRC48-ADC\u5355\u836f\u6cbb\u7597\u65e2\u5f80\u5e38\u89c4\u6cbb\u7597\u540e\u8fdb\u5c55\u7684HER2\u9633\u6027\u8868\u8fbe\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u5c3f\u8def\u4e0a\u76ae\u764c\uff0c\u7597\u6548\u663e\u8457\uff0c\u4e0d\u826f\u53cd\u5e94\u53ef\u63a7\uff0c\u503c\u5f97\u8fdb\u4e00\u6b65\u63a2\u7d22\u3002<\/div>\n
4. \u901a\u8fc7\u6211\u4eec\u7684\u52aa\u529b\uff0c\u6709\u53ef\u80fd\u6210\u4e3a\u5168\u7403\u7b2c\u4e00\u4e2a\u4e0a\u5e02\u7528\u4e8e\u8180\u80f1\u5c3f\u8def\u4e0a\u76ae\u764c\u6cbb\u7597\u7684ADC\u836f\u7269\u3002<\/div>\n
\u00a0<\/div>\n
\u80ba\u764c\u6700\u65b0\u5b66\u672f\u8fdb\u5c55\u53ca\u80ba\u764c\u8bca\u7597\u63a8\u52a8\u4e13\u573a\u00a0<\/div>\n
\uff08\u65f6\u95f4\uff1a9\u670822\u65e5 08:30-12:00\uff09<\/div>\n\n
\n![\"?wx_fmt=jpeg\"\/](\"https:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/RmFicvQBAkgDtjXsEYibX7SY8zvu0kuWI97wicaXviaOqyMNNXZFu4Iia0eOPJx01c8DAPX9DW8EMDrlZuEPN9mZfcA\/?wx_fmt=jpeg\")
<\/figure><\/div>\n\n
\u25c6\u00a0\u7a0b\u9896\uff08\u5409\u6797\u7701\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u665a\u671f NSCLC\u8054\u5408\u6cbb\u7597\u7684\u73b0\u72b6\u4e0e\u53d1\u5c55\u65b9\u5411\u300b<\/div>\n
1. \u836f\u7269\u8054\u5408\u6cbb\u7597\u6a21\u5f0f\uff1a<\/div>\n
1\uff09TKI\u4e3a\u57fa\u7840\u7684\u8054\u5408\u6cbb\u7597\u6a21\u5f0f\uff1a\u8054\u5408\u5316\u7597\uff08FASTACT-2\u3001NEJ005\u7b49\uff09\u3001\u6297\u8840\u7ba1\u3001\u514d\u75ab\uff08Checkmate012\u3001Checkmate370\uff09\u3001\u9776\u5411\u3002<\/div>\n
2\uff09\u4ee5\u514d\u75ab\u4e3a\u57fa\u7840\u7684\u8054\u5408\u6cbb\u7597\u6a21\u5f0f\uff1a\u5316\u7597\uff08CM012\u3001CM227\u7b49\uff09\u3001\u6297\u8840\u7ba1\uff08Impower150\u7b49\uff09\u3001\u9776\u5411\uff08JAKi\u3001FAKi\u7b49\uff09\u3001\u514d\u75ab\uff08TIM3\u3001LAG\u7b49\uff09\u3002<\/div>\n
3. TKI+\u5316\u75972\u671f\u7814\u7a76\u7684PFS\u53ef\u4ee5\u4e0e\u4e09\u4ee3TKI\u4e00\u7ebf\u6cbb\u7597\u7684PFS\u5ab2\u7f8e\uff0cORR\u5177\u6709\u4f18\u52bf\uff0cOS\u6709\u5ef6\u957f\u8d8b\u52bf\u3002<\/div>\n
4. NEJ009\u7814\u7a76\uff1a3\u671f\u8bd5\u9a8c\u8bc1\u5b9eTKI+\u5316\u7597\u6539\u5584PFS\u3001ORR\u548cOS\uff0c\u8054\u5408\u7ec4\u80bf\u7624\u8d1f\u8377\u4f18\u4e8e\u5355\u836f\u7ec4\u3002<\/div>\n
5. TKI+\u6297\u8840\u7ba1\u6cbb\u7597\uff1aA+T\u4e00\u7ebf\u6cbb\u7597EGFR\u7a81\u53d8NSCLC\u83b7\u5f97PFS\u6539\u5584\uff0c2\u671f\u7814\u7a76\u7ed3\u679c\u6ca1\u6709OS\u83b7\u76ca\uff0c\u4f46\u83b7\u5f97\u957f\u8fbe4\u5e74\u751f\u5b58\u3002<\/div>\n
6. \u4e0e\u514d\u75ab\u5355\u836f\u76f8\u6bd4\uff0c\u514d\u75ab+\u5316\u7597\u6709\u66f4\u9ad8\u5ba2\u89c2\u7f13\u89e3\u7387\uff0c\u8054\u5408\u6cbb\u7597PFS\u6709\u66f4\u957f\u8d8b\u52bf\uff1bPemb\u8054\u5408Ramucirumab\u5728\u665a\u671fNSCLC 3\u7ebf\u4ee5\u4e0a\u6cbb\u7597\u83b7\u5f9725% ORR\u548c\u6301\u7eed\u4e34\u5e8a\u83b7\u76ca\uff1b\u5728NSCLC\u4e2dnivo+IPI\u662f\u7814\u7a76\u6700\u65e9\uff0cnivo\u8054\u5408ips\u8f83nivo\u5355\u836f\u66f4\u5177\u4f18\u52bf\u3002<\/div>\n
7. \u514d\u75ab\u8868\u578b\u5f71\u54cdTKI\u7597\u6548\uff1a\u5728EGFR\u7a81\u53d8\u60a3\u8005\u4e2dPD-L1\u9ad8\u8868\u8fbe\u662f\u6cbb\u7597\u53cd\u5e94\u4e0d\u4f73\u7684\u9884\u540e\u56e0\u5b50\uff0cPD-L1\u9ad8\u8868\u8fbe\u662fTKI\u539f\u53d1\u8010\u836f\u56e0\u7d20\u4e4b\u4e00\uff1b\u9ad8TMB\u7684EGFR\u7a81\u53d8NSCLC\u63a5\u53d7TKI\u6cbb\u7597\u5177\u6709\u66f4\u77ed\u7684TTD\u548cOS\uff0c\u9ad8TMB\u4e0eEGFR\u7a81\u53d8NSCLC\u8fdb\u884cTKI\u6cbb\u7597\u7684\u7597\u6548\u8d1f\u76f8\u5173\u3002<\/div>\n
8. TKI\u8054\u5408nivo\u5177\u6709\u826f\u597d\u8010\u53d7\u6027\uff0c\u5bf9\u4e8eTKI\u7ecf\u6cbb\u60a3\u8005\uff0c\u5c3c\u6d1b\u66ff\u5c3c\u8054\u5408nivo\u5177\u6709\u6301\u4e45\u7597\u6548\uff0c\u5c24\u5176\u662fPD-L1\u8868\u8fbe\u7684\u60a3\u8005\uff1bALK+\u514d\u75ab\u6cbb\u7597\u5e76\u672a\u5e26\u6765\u989d\u5916\u83b7\u76ca\uff0c\u4e14\u6bd2\u6027\u589e\u52a0\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u738b\u957f\u5229 \u97e9\u9896\uff08\u5929\u6d25\u5e02\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300aNSCLC\u65b0\u8f85\u52a9\u514d\u75ab\u6cbb\u7597\u8fdb\u5c55\u300b<\/div>\n
1. NSCLC\u65b0\u8f85\u52a9\u514d\u75ab\u6cbb\u7597\u6d41\u7a0b\uff1a\u65b0\u8bca\u65ad\u53ef\u5207\u9664\uff08\uff1e2cm\uff0c\u2160-\u2162\u671fNSCLC\uff09\u2192Nivo 3mg\/kg\uff0814\u5929&28\u5929\uff09\u2192\u624b\u672f\u5207\u9664\uff080\u5929\uff09\u2192\u672f\u540e\u6807\u51c6\u6cbb\u7597\u3002<\/div>\n
1\uff09\u4e3b\u8981\u7ec8\u70b9\u5305\u62ec\uff1a\u836f\u7269\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\u3001\u65e0\u5ef6\u671f\uff08\u81ea\u672f\u524d\u8ba1\u5212\u65e5\u671f\uff1e37\u5929\uff09\u3001\u624b\u672f\u5207\u9664\u7684\u53ef\u884c\u6027\u3002<\/div>\n
2\uff09\u63a2\u7d22\u6027\u7ec8\u70b9\uff1a\u75c5\u7406\u5b66\u7f13\u89e3\u3001\u660e\u786e\u514d\u75ab\u5e94\u7b54\u7684\u57fa\u56e0\u7ec4\u9884\u6d4b\u56e0\u5b50\u3001\u8bf1\u5bfc\u7cfb\u7edf\u6297\u80bf\u7624T\u7ec6\u80de\u53cd\u5e94\u7684\u514d\u75ab\u5b66\u8bc1\u636e\u3002<\/div>\n
3\uff09\u836f\u7269\u76f8\u5173\u4e0d\u826f\u4e8b\u4ef6\uff08N=22\uff09\uff0c\u53ef\u884c\u6027\uff1aNivo\u672a\u5ef6\u671f\u6216\u5f71\u54cd\u624b\u672f\uff1b\u5b89\u5168\u6027\uff1a\u624b\u672f\u540e\u5b89\u5168\u671f1\u4f8b\u6b7b\u4ea1\u4f46\u4e0e\u7814\u7a76\u836f\u7269\u65e0\u5173\u3002<\/div>\n
4\uff09\u7ed3\u8bba\uff1a\u5b89\u5168\u6027\u597d\uff1b\u53ef\u5207\u9664\u60a3\u8005\u75c5\u4f8b\u7f13\u89e3\u738745%\uff1b\u75c5\u7406\u5b66\u7f13\u89e3\u4e0e\u7a81\u53d8\u8d1f\u8377\u76f8\u5173\uff1bNivo\u8f85\u52a9NSCLC\u540e\u80bf\u7624\u7f13\u89e3\uff1bNivo\u65b0\u8f85\u52a9\u6cbb\u7597\u540e\uff0c\u5916\u5468\u8840\u4e2d\u53d1\u73b0\u4f18\u52bf\u7a81\u53d8\u76f8\u5173\u65b0\u6297\u539f\uff08MANAs\uff09\u7279\u5f02\u6027T\u7ec6\u80de\u6269\u589e\u3002<\/div>\n
3. \u4ec5\u6709\u5c11\u6570\u60a3\u8005\u4ece\u5355\u836f\u514d\u75ab\u6cbb\u7597\u4e2d\u53d7\u76ca\uff0c\u5728\u672a\u7ecf\u7b5b\u9009\u7684NSCLC\u4e2d\uff0c\u514d\u75ab\u6cbb\u7597\u7684\u6709\u6548\u7387\u7ea614%-20%\u3002<\/div>\n
4.Checkmate 227\uff1aPD-L1\uff1c1%\u4e14\u226510mut\/MB\uff0cNivo+chemo\u7ec4PFS\u663e\u8457\u5ef6\u957f\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u675f\u6c38\u524d\uff08\u6c5f\u82cf\u7701\u4eba\u6c11\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u65b0\u578b\u7ec6\u80de\u6bd2\u6027\u836f\u7269\u7814\u7a76\u8fdb\u5c55\u300b<\/div>\n
1. \u7d2b\u6749\u836f\u7269\u96be\u6eb6\u4e8e\u6c34\uff0c\u9700\u501f\u52a9\u6eb6\u5242\uff08\u6709\u6bd2\uff09\uff0c\u5bfc\u81f4\u5316\u7597\u7597\u6548\u964d\u4f4e\u3001\u6bd2\u6027\u53cd\u5e94\u589e\u52a0\u7b49\u3002\u7eb3\u7c73\u767d\u86cb\u767d\u7d2b\u6749\u9187\u4e00\u7ebf\u6cbb\u7597\u665a\u671fNSCLC\uff1a\u7eb3\u7c73\u767d\u86cb\u767d\u7d2b\u6749\u9187\u7ec4\u7597\u6548\u4e0d\u5dee\u4e8e\u6eb6\u5242\u578b\u7d2b\u6749\u9187\u7ec4\uff0c\u800c\u4e14\u8001\u5e74\u60a3\u8005\u83b7\u76ca\u663e\u8457\u3002<\/div>\n
2. \u6297\u4f53\u5076\u8054\u836f\u7269\uff08ADC\uff09\u5728NSCLC\u4e2d\u7684\u63a2\u7d22\uff1a<\/div>\n
1\uff09T-DM1\uff1a\u662f\u4e00\u79cd\u9776\u5411HER2\u7684\u6297\u4f53\u5076\u8054\u836f\u7269\uff0c\u76ee\u524d\u5df2\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597HER2\u9633\u6027\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u60a3\u8005\u3002HER-2 IHC3+\u60a3\u8005\u4f7f\u7528T-DM1\u53ef\u80fd\u751f\u5b58\u83b7\u76ca\u66f4\u663e\u8457\u3002<\/div>\n
2\uff09DS-8201a\uff1a\u662f\u4e00\u79cd\u9776\u5411HER2\uff0c\u5076\u8054\u62d3\u6251\u5f02\u6784\u9176I\u6291\u5236\u5242\u4f0a\u6c99\u66ff\u5eb7\u884d\u751f\u7269\u3002<\/div>\n
3\uff09IMMU-132\uff1a\u9776\u5411\u836f\u90e8\u5206Trop-2\u6297\u4f53\u548c\u5316\u7597\u836f\u90e8\u5206SN-38\u5728\u591a\u7ebf\u6cbb\u7597\u5931\u8d25\u7684TNBC\u60a3\u8005\uff0850%\u63a5\u53d7\u8fc75\u79cd\u836f\u7269\u6cbb\u7597\uff09\uff0cIMMU-132\u6709\u6548\u7387\u9ad8\u8fbe30%\uff0c\u4f7f69.5%\u60a3\u8005\u80bf\u5757\u6d88\u9000\u3002<\/div>\n
3. ADC\u5728SCLC\u4e2d\u7684\u63a2\u7d22\uff1a<\/div>\n
1\uff09\u665a\u671fSCLC\u56f0\u5883\uff1a\u8fd120\u5e74\u65e0\u65b0\u578b\u5316\u7597\u836f\u4e0a\u5e02\u3002<\/div>\n
2\uff09Rova-T\uff1a\u9776\u5411Notch\u914d\u4f53DLL3\u7684\u6297\u4f53\u5076\u8054\u7269\uff0c\u662f\u9996\u4e2a\u6cbb\u7597SCLC\u6709\u6548\u7684\u9776\u5411\u836f\uff0cDLL3\u53ef\u80fd\u6210\u4e3a\u9884\u6d4b\u7597\u6548\u7684\u6807\u5fd7\u7269\u3002<\/div>\n
3\uff09IMGN901\uff1a\u9776\u5411\u836f\u90e8\u5206CD56\u6297\u4f53\u548c\u5316\u7597\u836f\u90e8\u5206DM1\uff0c\u81f4\u547d\u6bd2\u6027\uff0c\u7597\u6548\u5dee\u5f3a\u4eba\u610f\uff0c\u653e\u5f03\u3002<\/div>\n
4\uff09IMMU-132\uff1a\u4e2d\u4f4d\u54cd\u5e94\u65f6\u95f42\u4e2a\u6708\uff1b\u4e2d\u4f4d\u5e94\u7b54\u6301\u7eed\u65f6\u95f45.7\u6708\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u738b\u7acb\u5cf0\uff08\u5357\u4eac\u9f13\u697c\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300aCheckpoint\u6291\u5236\u5242\u8010\u836f\u673a\u5236\u4e0e\u5e94\u5bf9\u300b<\/div>\n
1. \u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u9762\u4e34\u7684\u6311\u6218\uff1a\u6240\u6709\u60a3\u8005\u53ef\u80fd\u83b7\u76ca\u4e5f\u53ef\u80fd\u8010\u836f\uff1b2\u7ebfORR 20%\uff1b1\u7ebfPD-L1\u9ad8\u8868\u8fbe\u4eba\u7fa4ORR 45%\u3002<\/div>\n
2. IO\u8010\u836f\u4e34\u5e8a\u5206\u7c7b\uff1aprimary resistance\u3001adaptive immune resistance\u3001acquired resistance\u3002\u514d\u75ab\u8010\u836f\u53ef\u80fd\u53d1\u751f\u5728\u514d\u75ab\u53cd\u5e94\u6240\u6709\u73af\u8282\u3002<\/div>\n
3. \u514d\u75ab\u8010\u836f\u7684\u5185\u5728\u673a\u5236\uff1a\u5927\u591a\u6e90\u81ea\u764c\u57fa\u56e0\u7684\u6fc0\u6d3b\u7a81\u53d8\u6216\u6291\u764c\u57fa\u56e0\u7684\u529f\u80fd\u4e22\u5931\u7a81\u53d8\uff0c\u5305\u62ec\u7f3a\u4e4f\u4ea7\u751f\u6297\u539f\u6027\u7684\u7a81\u53d8\u3001\u6297\u539f\u8868\u8fbe\u7f3a\u5931\u3001\u6297\u539f\u9012\u5448\u7f3a\u9677\u3001\u4fe1\u53f7\u4f20\u5bfc\u901a\u8def\u6539\u53d8\u3001\u8868\u89c2\u9057\u4f20\u4fee\u9970\u3001HLA\u8868\u8fbe\u4e22\u5931\u3002<\/div>\n
4. \u514d\u75ab\u8010\u836f\u7684\u5916\u5728\u673a\u5236\uff1a\u80bf\u7624\u6240\u5904\u7684\u5fae\u73af\u5883\uff0c\u5305\u62ecCTLA-4\u3001PD-1\u548c\u5176\u4ed6\u514d\u75ab\u68c0\u67e5\u70b9\uff1bT\u7ec6\u80de\u8017\u7aed\u548c\u8868\u578b\u6539\u53d8\uff1b\u514d\u75ab\u6291\u5236\u7ec6\u80de\uff1b\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7684\u7ec6\u80de\u56e0\u5b50\u53ca\u4ee3\u8c22\u4ea7\u7269\u3002<\/div>\n
5. \u80a0\u9053\u5fae\u751f\u7269\u53ef\u4ee5\u5f71\u54cd\u5c40\u90e8\u514d\u75ab\u5fae\u73af\u5883\uff1a\u542b\u7279\u5b9a\u80a0\u9053\u5fae\u751f\u7269\u7fa4\u7684\u60a3\u8005\u63a5\u53d7\u514d\u75ab\u6cbb\u7597\u7597\u6548\u597d\u3002<\/div>\n
6. \u5b9e\u65f6\u52a8\u6001\u76d1\u6d4b\uff0c\u4e0d\u540c\u7b56\u7565\u5e94\u5bf9\u51b7\u70ed\u80bf\u7624\u3002\u8054\u5408\u8868\u89c2\u9057\u4f20\u9776\u5411\u6291\u5236\u5242\u514b\u670d\u514d\u75ab\u8010\u836f\u3001\u8054\u5408\u80a0\u9053\u5fae\u751f\u7269\u7ec4\u5b66\u514b\u670d\u514d\u75ab\u8010\u836f\u3001\u8054\u5408\u6cbb\u7597\u514b\u670dIO\u8010\u836f\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u67f3\u83c1\u83c1\uff08\u5409\u6797\u7701\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u5c0f\u7ec6\u80de\u80ba\u764c\u65b0\u836f\u7814\u7a76\u8fdb\u5c55\u300b<\/div>\n
1. SCLC\u65b0\u836f\u7814\u7a76\u70ed\u70b9\uff1a\u514d\u75ab\u9776\u5411\u6cbb\u7597\u3001\u9776\u5411DLL3\u3001\u6297\u8840\u7ba1\u751f\u6210\u836f\u7269\u3001\u9776\u5411DDR\u3001\u5316\u7597\u836f\u7269\u3002<\/div>\n
2. SCLC\u514d\u75ab\u9776\u5411\u836f\u7269\u7814\u7a76\u70ed\u70b9\uff1a\u4ece\u590d\u53d1\/\u8010\u836f\u2192\u521d\u6cbb\u60a3\u8005\uff1b\u4ece\u5355\u836f\u5230\u8054\u5408\uff08IO+IO\u3001IO+\u5316\u7597\u3001IO+\u9776\u5411\uff09\u5747\u6709\u5c1d\u8bd5\uff1b\u6807\u5fd7\u7269\u4ece\u975e\u9009\u62e9\u5230\u9009\u62e9\uff08PD-L1\u3001TMB\uff09\u3002<\/div>\n
3. 2017\u5e74V1\u7248\u672cNCCN\u6307\u5357\u5c06nivo+Ipilimumab\u5217\u5165\u6cbb\u7597\u5c0f\u7ec6\u80de\u80ba\u764c\u591a\u7ebf\u6cbb\u7597\u9009\u62e9\uff1b20\u5e74\u6765SCLC\u9996\u4e2a\u83b7\u6279\u65b0\u836f\uff1a2018\u5e748\u6708nivo\u76ee\u524d\u552f\u4e00\u4e00\u4e2a\u88abFDA\u6279\u51c6\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u542b\u94c2\u65b9\u6848\u5316\u7597\u4ee5\u53ca\u81f3\u5c11\u4e00\u79cd\u5176\u4ed6\u7597\u6cd5\u540e\u75be\u75c5\u8fdb\u5c55\u7684\u8f6c\u79fb\u6027SCLC\u60a3\u8005\u7684IO\u836f\u7269\u3002<\/div>\n
4. \u5bf9\u975e\u9009\u62e9\u4eba\u7fa4\u514d\u75ab\u8054\u5408\u6cbb\u7597\u7597\u6548\u4f18\u4e8e\u5355\u836f\uff1b\u5355\u836f\u6cbb\u7597\u4e2dPD-1\u6297\u4f53\u8868\u73b0\u66f4\u7a81\u51fa\u3002<\/div>\n
5. Pembro\u5355\u836f\u5728PD-L1\u9633\u6027\u590d\u53d1ED-SCLC\u60a3\u8005\u4e2d\u5177\u6709\u826f\u597d\u6297\u80bf\u7624\u6d3b\u6027\u3002Keynote158\u8bc1\u5b9ePD-L1\u53ef\u4ee5\u4f5c\u4e3aPembro\u5355\u836f\u6cbb\u7597\u7684\u6807\u5fd7\u7269\uff0cPD-L1\u9633\u6027\u60a3\u8005\u6709\u66f4\u597d\u7597\u6548\u548c\u751f\u5b58\u83b7\u76ca\u3002<\/div>\n
6. \u514d\u75ab\u6cbb\u7597\u5f00\u521b\u4e86SCLC\u6cbb\u7597\u65b0\u5c40\u9762\uff0c\u83b7\u76ca\u4eba\u7fa4\u3001\u751f\u7269\u6807\u5fd7\u7269\u3001\u7528\u836f\u7b56\u7565\u7b49\u4ecd\u9700\u8fdb\u4e00\u6b65\u63a2\u7d22\u3002<\/div>\n
7. Rova-T\u7b49\u9776\u5411\u6cbb\u7597\u836f\u7269\u4f7f\u4eba\u4eec\u5bf9SCLC\u7cbe\u51c6\u533b\u7597\u6709\u4e86\u65b0\u8ba4\u8bc6\uff0c\u6709\u671b\u6210\u4e3a\u63a8\u8fdbSCLC\u7cbe\u51c6\u6cbb\u7597\u7684\u843d\u811a\u70b9\u3002<\/div>\n
8. \u65b0\u578b\u5316\u7597\u836f\u7269\u5728SCLC\u521d\u6b65\u663e\u793a\u51fa\u8f83\u597d\u7684\u6d3b\u6027\uff0c\u6bd2\u6027\u503c\u5f97\u5173\u6ce8\u3002<\/div>\n
\u00a0<\/div>\n
\u5987\u79d1\u80bf\u7624<\/div>\n
\u5375\u5de2\u764c\u3001\u5bab\u9888\u53ca\u5bab\u4f53\u80bf\u7624\u4e13\u573a<\/div>\n
\uff08\u65f6\u95f4\uff1a9\u670822\u65e5 8:30-12:00\uff09<\/div>\n
\u25c6\u00a0\u738b\u9759 \u6559\u6388\uff08\u6e56\u5357\u7701\u80bf\u7624\u533b\u9662\uff09<\/div>\n
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1.\u00a0\u00a0\u5728\u5375\u5de2\u6076\u6027\u80bf\u7624\u4e2d\uff0c\u4e0a\u76ae\u7ec6\u80de\u80bf\u7624\u536090%\uff0c\u95f4\u8d28\u80bf\u7624\u53607%\uff0c\u751f\u6b96\u7ec6\u80de\u80bf\u7624\u53603%\u3002<\/div>\n
2.\u00a0\u00a0\u5375\u5de2\u764c\u75c5\u56e0\u81f3\u4eca\u4e0d\u660e\u786e\uff0c\u76ee\u524d\u8ba4\u4e3a\u5375\u5de2\u764c\u7684\u5371\u9669\u56e0\u7d20\u6709BRCA1\u6216BRCA2\u7a81\u53d8\u5bb6\u65cf\u53f2\u3001\u5e74\u9f84\u589e\u957f\u3001\u539f\u53d1\u6027\u4e0d\u5b55\u75c7\u3001\u5b50\u5bab\u5185\u819c\u5f02\u4f4d\u75c7\u7b49\u3002<\/div>\n
3.\u00a0\u00a0\u9884\u9632\u5375\u5de2\u764c\u7684\u65b9\u6cd5\u6709\u624b\u672f\u5e72\u9884\u3001\u6291\u5236\u6392\u5375\u548c\u5b55\u6fc0\u7d20\u8c03\u8282\u3002<\/div>\n
4.\u00a0\u00a0\u5bfb\u627e\u66f4\u4f18\u7684\u5375\u5de2\u65e9\u7b5b\u6807\u8bb0\u7269\uff0c\u9884\u9632\u6027\u5207\u9664\u8f93\u5375\u7ba1\uff0c\u7ee7\u7eed\u5b55\u6fc0\u7d20\u9884\u9632\u5375\u5de2\u764c\u7684\u7814\u7a76\u3002<\/div>\n
\u00a0<\/div>\n
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1.\u00a0\u00a0\u6cbb\u7597\u539f\u5219\uff0c\u624b\u672f\u548c\u653e\u7597\u9996\u9009\u6839\u6cbb\u6027\u6cbb\u7597\uff0c\u5f53\u653e\u7597\u65f6\u5e94\u540c\u6b65\u653e\u5316\u7597\uff0c\u5c3d\u53ef\u80fd\u907f\u514d\u5316\u7597-\u624b\u672f\u3001\u653e\u7597\u4e09\u91cd\u6cbb\u7597\u3002<\/div>\n
2.\u00a0\u00a0\u5b58\u5728\u4e89\u7684\u8bae\u5305\u62ec\u4e34\u5e8a\u5206\u671f\u4e0e\u624b\u672f\u75c5\u7406\u5206\u671f\u51c6\u786e\u6027\u3001\u672f\u524d\u65b0\u8f85\u52a9\u5316\u7597\u5e7f\u6cdb\u5e94\u7528\u4e0e\u60a3\u8005\u751f\u5b58\u83b7\u76ca\u6027\u3001\u624b\u672f\u5206\u578b\u6f14\u5316\u4e0e\u4e2a\u4f53\u5316\u624b\u672f\u6cbb\u7597\u9009\u62e9\u6027\u3001\u5fae\u521b\u624b\u672f\u4e0e\u4f20\u7edf\u5f00\u8179\u624b\u672f\u4f18\u52a3\u6027\u548c\u4fdd\u80b2\u624b\u672f\u7684\u6307\u8bc1\u6269\u5927\u4e0e\u598a\u5a20\u7387\u964d\u4f4e\u6298\u8877\u6027\u7b49\u3002<\/div>\n
3.\u00a0\u00a0\u624b\u672f\u75c5\u7406\u5206\u671f\u63d0\u4f9b\u51c6\u786e\u6027\u9884\u540e\u4fe1\u606f\u6307\u5bfc\u672f\u540e\u6cbb\u7597\uff0c\u624b\u672f\u6cbb\u7597\u4e2a\u4f53\u5316\u9009\u62e9\u6027\uff0c\u4fdd\u8bc1\u80bf\u7624\u5b89\u5168\u6027\uff0c\u63d0\u9ad8\u751f\u6d3b\u8d28\u91cf\u3002<\/div>\n
4.\u00a0\u00a0\u65b0\u8f85\u52a9\u5316\u7597\u867d\u5e7f\u6cdb\u5e94\u7528\uff0c\u4f46\u60a3\u8005\u751f\u5b58\u4e0d\u80fd\u83b7\u76ca\u6027\uff0c\u7528\u4e8e\u4fdd\u7559\u751f\u80b2\u624b\u672f\u6216\u8d44\u6e90\u532e\u4e4f\u5730\u533a\u3002<\/div>\n
5.\u00a0\u00a0\u4e0e\u4f20\u7edf\u5f00\u8179\u624b\u672f\u76f8\u6bd4\uff0c\u5fae\u521b\u624b\u672f\u6613\u590d\u53d1\u3001\u751f\u5b58\u7387\u964d\u4f4e\uff0c\u5e94\u627e\u5230\u5408\u9002\u60a3\u8005\u3002<\/div>\n
\u00a0<\/div>\n
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1.\u00a0\u00a0\u665a\u671f\u5185\u819c\u764c\u5e38\u89c4\u6cbb\u7597\u4e94\u5e74\u751f\u5b58\u7387\u4ec5\u4e3a5%\u5de6\u53f3\u3002<\/div>\n
2.\u00a0\u00a0\u5206\u5b50\u5206\u578b\u8fc7\u7a0b\u4e2d\u5b58\u5728\u7684\u95ee\u9898\uff1a\u80bf\u7624\u7684\u7ec4\u7ec7\u5b66\u7c7b\u578b\u80fd\u5426\u51c6\u786e\u91cd\u590d\u5730\u754c\u5b9a\u3001\u5982\u4f55\u6539\u5584\u60a3\u8005\u590d\u53d1\u6216\u6b7b\u4ea1\u7684\u98ce\u9669\u5206\u5c42\u3001\u80fd\u5426\u5e94\u7528\u4e8e\u6307\u5bfc\u6cbb\u7597\u4ec5\u53ef\u624b\u672f\u6216\u9002\u5408\u4fdd\u7559\u751f\u80b2\u529f\u80fd\u548c\u521d\u59cb\u6cbb\u7597\u540e\u9002\u5f53\u7684\u76d1\u6d4b\u624b\u6bb5\u7b49\u3002<\/div>\n
3.\u00a0\u00a0\u9776\u5411\u6cbb\u7597\u524d\u666f\u5e7f\u6cdb\u4f46\u9700\u5efa\u7acb\u5728\u5206\u5b50\u5206\u578b\u4ee5\u8fbe\u5230\u7cbe\u51c6\u9776\u70b9\u6cbb\u7597\u3002<\/div>\n
4.\u00a0\u00a0\u5206\u5b50\u5206\u578b\u8fd8\u5904\u4e8e\u521d\u7ea7\u9636\u6bb5\uff0c\u7531\u4e8e\u7ec4\u7ec7\u548c\u7ec6\u80de\u7684\u5f02\u578b\u6027\u662f\u5206\u578b\u548c\u9776\u70b9\u4e4b\u95f4\u543b\u5408\u66f4\u590d\u6742\u3002<\/div>\n
5.\u00a0\u00a0\u5efa\u7acb\u5728\u4e34\u5e8a\u5206\u5b50\u5206\u578b\u57fa\u7840\u4e0a\uff0c\u5206\u5b50\u57fa\u56e0\u68c0\u6d4b\u7528\u4e8e\u5224\u65ad\u548c\u9884\u6d4b\u9776\u5411\u548c\u4e2a\u4f53\u5316\u5316\u7597\u6cbb\u7597\u66f4\u6709\u6548\u3002<\/div>\n
\u00a0<\/div>\n
\u7ed3\u76f4\u80a0\u764c\u89c4\u8303\u5316\u548c\u591a\u5b66\u79d1\u8bca\u6cbb\u4e13\u573a<\/div>\n
\uff08\u65f6\u95f4\uff1a9\u670822\u65e5 8:30-12:00\uff09<\/div>\n\n
\n![\"?wx_fmt=jpeg\"\/](\"https:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/RmFicvQBAkgDtjXsEYibX7SY8zvu0kuWI9QqAQBJMeevSXcEscBhaYvpWJjljX1k9gHIlzfSV62uHqExjicun1rug\/?wx_fmt=jpeg\")
<\/figure><\/div>\n\n
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1.\u00a0\u00a0\u665a\u671f\u80a0\u764c\u7cfb\u7edf\u6cbb\u7597\u7684\u53d1\u5c55\u65b9\u5411\uff0c\u57fa\u4e8e\u751f\u7269\u6807\u8bb0\u7269\u7684\u7cbe\u51c6\u6cbb\u7597\uff0c\u65b0\u836f\u548c\u65b0\u6cbb\u7597\u6a21\u5f0f\u7684\u63a2\u7d22\uff0c\u51cf\u8f7b\u526f\u4f5c\u7528\u63d0\u4f9b\u751f\u5b58\u8d28\u91cf\u3002<\/div>\n
2.\u00a0\u00a0\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u9700\u8981\u68c0\u6d4bRAS\u3001BRAF\u3001HER2\u53caMSI\u7b49\u5206\u5b50\u6807\u8bb0\u7269\uff0c\u5e76\u6839\u636e\u8fd9\u4e9b\u57fa\u56e0\u72b6\u6001\u53ca\u539f\u53d1\u7076\u90e8\u4f4d\u5236\u5b9a\u6cbb\u7597\u65b9\u6848\u3002<\/div>\n
3.\u00a0\u00a0\u4e00\u7ebf\u6cbb\u7597\u540e\u53ef\u8003\u8651\u4f7f\u7528\u7ef4\u6301\u6cbb\u7597\u7b56\u7565\u5ef6\u957f\u65e0\u8fdb\u5c55\u751f\u5b58\uff0c\u4e8c\u7ebf\u6cbb\u7597\u53ef\u91c7\u7528mXELIRI\u7b49\u65b0\u65b9\u6848\u964d\u4f4e\u6bd2\u6027\u3001\u7b80\u4fbf\u4f7f\u7528\u3002<\/div>\n
4.\u00a0\u00a0\u91c7\u7528\u6db2\u4f53\u6d3b\u68c0\u7b49\u65b0\u6280\u672f\uff0c\u53ef\u5b9e\u73b0\u65e9\u8bca\u53ca\u9884\u540e\u76d1\u6d4b\u3002<\/div>\n
5.\u00a0\u00a0\u53d1\u73b0\u4e0e\u80a0\u764c\u8f6c\u79fb\u3001\u8010\u836f\u76f8\u5173\u5206\u5b50\u6807\u7b7e\uff0c\u6307\u5bfc\u4e34\u5e8a\u8bca\u6cbb\u3002<\/div>\n
6.\u00a0\u00a0\u73b0\u5f00\u5c55\u7684\u7cfb\u5217\u4e34\u5e8a\u7814\u7a76\uff0c\u4f18\u5316\u4e34\u5e8a\u7814\u7a76\u6a21\u5f0f\uff0c\u591a\u9879\u6210\u679c\u88ab\u56fd\u9645\u3001\u56fd\u5185\u6307\u5357\u91c7\u7eb3\uff0c\u4e8e\u5168\u7403\u63a8\u5e7f\u5e94\u7528\u3002<\/div>\n
\u00a0<\/div>\n
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1.\u00a0\u00a0\u809d\u8f6c\u79fb\u662f\u8bca\u7597\u7684\u91cd\u70b9\u4e0e\u96be\u70b9\uff0c50%CRC\u6709\u809d\u8f6c\u79fb\uff0c15%-25%CRC\u8bca\u65ad\u65f6\u5df2\u6709\u540c\u65f6\u6027\u809d\u8f6c\u79fb\uff0c\u53e615%-25%CRC\u672f\u540e\u51fa\u73b0\u5f02\u65f6\u6027\u809d\u8f6c\u79fb\u3002<\/div>\n
2.\u00a0\u00a0\u4ec510%-20%\u809d\u8f6c\u79fb\u521d\u59cb\u53ef\u624b\u672f\uff0c\u4e0d\u80fd\u624b\u672f\u7684\u809d\u8f6c\u79fb\u60a3\u80055\u5e74\u751f\u5b58\u7ea65%\uff0c\u672a\u6cbb\u7597\u809d\u8f6c\u79fb\u4e2d\u4f4d\u751f\u5b58\u4ec56.9\u4e2a\u6708\u3002<\/div>\n
3.\u00a0\u00a0\u624b\u672f\u662f\u7ed3\u76f4\u80a0\u764c\u809d\u8f6c\u79fb\u4e3b\u8981\u6cbb\u7597\u65b9\u6cd5\uff0c\u53ef\u5207\u9664\u7684\u809d\u8f6c\u79fb\u80a0\u764c\u53ef\u6269\u5927\u624b\u672f\u9002\u5e94\u75c7\u3001\u540c\u671f\u5207\u9664\u548c\u5fae\u521b\u624b\u672f\uff0c\u4e0d\u53ef\u5207\u9664\u7684\u809d\u8f6c\u79fb\u80a0\u764c\u53ef\u8f6c\u5316\u6cbb\u7597\u3001\u5e8f\u8d2f\u6cbb\u7597\u548c\u5207\u9664\u539f\u53d1\u7076\u3002<\/div>\n
4.\u00a0\u00a0\u4e2d\u5c71\u533b\u9662\u6269\u5c55\u6807\u51c6\u5b9e\u65bd\u6548\u679c\uff0c\u6269\u5927\u624b\u672f\u9002\u5e94\u8bc1\u4e0d\u589e\u52a0\u624b\u672f\u5e76\u53d1\u75c7\u548c\u5bf9\u751f\u5b58\u671f\u65e0\u663e\u8457\u5f71\u54cd\u3002<\/div>\n
\u00a0<\/div>\n
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\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u7ed3\u76f4\u80a0\u764c\u80ba\u8f6c\u79fb\u591a\u5b66\u79d1\u7efc\u5408\u6cbb\u7597\u4e13\u5bb6\u5171\u8bc6\u300b<\/div>\n
1.\u00a0\u00a0\u5355\u7eaf\u540c\u65f6\u6027\u548c\u5f02\u65f6\u6027\u80ba\u8f6c\u79fb\u5360\u665a\u671f\u80a0\u764c\u768411%\u548c5.8%\uff0c\u540c\u65f6\u7684\u809d\u80ba\u8f6c\u79fb\uff0c\u80ba\u8f6c\u79fb\u7076\u5bf9\u9884\u540e\u672c\u8eab\u5f71\u54cd\u76f8\u5bf9\u8f83\u5c11\uff0c\u5173\u6ce8\u7a0b\u5ea6\u4f4e\uff0c\u7efc\u5408\u6cbb\u7597\u7406\u5ff5\u532e\u4e4f\uff0c\u4e34\u5e8a\u57fa\u7840\u7814\u7a76\u8fdb\u5c55\u7f13\u6162\u3002<\/div>\n
2.\u00a0\u00a0\u80ba\u8f6c\u79fb\u60a3\u8005\u589e\u52a0\uff0c\u4f46\u7f3a\u4e4f\u524d\u77bb\u6027\u968f\u673a\u5bf9\u7167\u7814\u7a76\u53ca\u6307\u5357\u63a8\u8350\u3002<\/div>\n
3.\u00a0\u00a0\u9700\u5f15\u8d77\u4e34\u5e8a\u533b\u751f\u548c\u79d1\u5b66\u5bb6\u5bf9\u7ed3\u76f4\u80a0\u764c\u80ba\u8f6c\u79fb\u7684\u91cd\u89c6\uff0c\u9f13\u52b1\u5408\u4f5c\u5bf9\u672a\u89e3\u51b3\u95ee\u9898\u5f00\u5c55\u4e34\u5e8a\u7814\u7a76\u3002<\/div>\n
4.\u00a0\u00a0\u4e86\u89e3\u76ee\u524d\u5b58\u5728\u4e89\u8bae\uff0c\u5f62\u6210\u76f8\u5bf9\u7edf\u4e00\u7684\u5171\u8bc6\u7ed9\u4e88\u4e34\u5e8a\u63a8\u8350\uff0c\u66f4\u65b0\u4fee\u8ba2\u5171\u8bc6\u7814\u7a76\u8fdb\u5c55\u548c\u8fdb\u884c\u4e13\u5bb6\u6295\u7968\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u7ae0\u771f\uff08\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u5c40\u90e8\u8fdb\u5c55\u671f\u76f4\u80a0\u764c\u7684\u6cbb\u7597\u89c4\u8303\u4e0e\u8fdb\u5c55\u300b<\/div>\n
1.\u00a0\u00a0\u672f\u524d\u5316\u7597\u662f\u5c40\u90e8\u665a\u671f\u76f4\u80a0\u764c\u5f53\u524d\u7684\u6807\u51c6\u6cbb\u7597\uff0c\u63a8\u8350\u6c1f\u5c3f\u5627\u5576\u7c7b\u836f\u7269\u5355\u836f\u8054\u5408\u653e\u7597\u3002<\/div>\n
2.\u00a0\u00a0\u8be5\u7fa4\u4f53\u662f\u4e00\u4e2a\u5145\u6ee1\u5f02\u8d28\u6027\u7684\u7fa4\u4f53\uff0c\u5355\u4e00\u7684\u6cbb\u7597\u6a21\u5f0f\u5e76\u975e\u6700\u4f73\u9009\u62e9\u3002<\/div>\n
3.\u00a0\u00a0CCR\u540e\u89c2\u5bdf\u7b49\u5f85\u6216\u5c40\u90e8\u5207\u9664\uff0c\u914d\u5408\u5bc6\u5207\u76d1\u6d4b\uff0c\u53ef\u6539\u5584\u751f\u6d3b\u8d28\u91cf\u5e76\u53d6\u5f97\u7406\u60f3\u9884\u540e\u3002<\/div>\n
4.\u00a0\u00a0\u6cbb\u7597\u65b9\u6848\u9700\u8981\u7efc\u5408\u6cbb\u7597\u76ee\u6807\u3001\u60a3\u8005\u7684\u610f\u613f\u6765\u51b3\u7b56\u3002<\/div>\n
5.\u00a0\u00a0\u5f71\u50cf\u5b66\u53ca\u5206\u5b50\u751f\u7269\u5b66\u7684\u53d1\u5c55\u4fc3\u8fdb\u7cbe\u51c6\u5206\u5c42\uff0c\u751f\u547d\u7684\u5ef6\u957f\u548c\u751f\u6d3b\u6cbb\u7597\u6539\u5584\u5e76\u91cd\u3002<\/div>\n
6.\u00a0\u00a0\u5206\u5c42\u6cbb\u7597\u8981\u8003\u8651\u5177\u6709\u6210\u719fMDT\u7efc\u5408\u6cbb\u7597\u7684\u4e2d\u5fc3\uff0c\u662f\u5728\u6709\u9ad8\u8d28\u91cfMRI\u5f71\u50cf\u53ca\u653e\u5c04\u8bca\u65ad\u533b\u5e08\u8fdb\u884c\u5206\u671f\u3002<\/div>\n
\u00a0<\/div>\n
\u4e73\u817a\u764c\u8bca\u7597\u4e13\u573a<\/div>\n
\uff08\u65f6\u95f4\uff1a9\u670822\u65e5 8:30-12:30\uff09<\/div>\n\n
\n![\"RmFicvQBAkgDtjXsEYibX7SY8zvu0kuWI9NDnmwiaFibuXOicdia2VTf99zt7sLNVkoLCevhCK7Jjr3JPb5x4suichLnA\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDtjXsEYibX7SY8zvu0kuWI9NDnmwiaFibuXOicdia2VTf99zt7sLNVkoLCevhCK7Jjr3JPb5x4suichLnA.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u25c6 \u8881\u8283 \u6559\u6388\uff08\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u7d2b\u6749\u7c7b\u836f\u7269\u5316\u7597\u5730\u4f4d\u548c\u4f18\u5316\u7ba1\u7406\u300b<\/div>\n
1. \u8fd120\u5e74\u7d2b\u6749\u7c7b\u4e3a\u9996\u836f\u7269\u7684\u521b\u65b0\u4e0e\u4f18\u5316\uff0c\u4e0d\u65ad\u6539\u5584\u4e2d\u56fd\u60a3\u8005\u7684\u9884\u540e\u3002<\/div>\n
2. ABC & WSG-Plan B\uff0c\u672a\u6765\uff1a\u5728\u8f6c\u5316\u6027\u7814\u7a76\u5bfb\u627e\u4e0d\u540c\u65b9\u6848\u7684\u654f\u611f\u6027\u6307\u6807\u6765\u533a\u522b\u4e0d\u540c\u7684\u9002\u5e94\u4eba\u7fa4\u3002<\/div>\n
3. \u8f85\u52a9\u5316\u7597\u65b9\u6848\u4e0d\u65ad\u524d\u8fdb\u7684\u4f18\u5316\u548c\u63a2\u7d22\uff0c\u9ad8\u4f4d\u60a3\u8005\u4f18\u9009\u79d8\u7c4d\u65b9\u6848\uff1a\u4eba\u7fa4\u9009\u62e9\uff0c\u6307\u5357\u63a8\u8350\uff0c\u4e0d\u826f\u53cd\u5e94\u3002<\/div>\n
4. \u7ea2\u8c46\u6749\u8d44\u6e90\u6709\u9650\uff0c\u5e94\u8003\u8651\u672a\u6765\u4eba\u5de5\u5408\u6210\u7d2b\u6749\u9187\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u5218\u5065 \u6559\u6388\uff08\u798f\u5efa\u7701\u80bf\u7624\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u4e73\u817a\u764c\u5316\u7597\u4f18\u5316\u7ba1\u7406\u4e4b\u6bd2\u6027\u7ba1\u7406\u300b<\/div>\n
1. \u7ef4\u6301\u6cbb\u7597\u5ef6\u957f\u4e86\u60a3\u8005\u7684PFS\uff0c\u4f46\u4e0d\u662fOS\u3002<\/div>\n
2. \u5c3d\u7ba1\u7ef4\u6301\u7ec4\u4e0e\u89c2\u5bdf\u7ec4\u7684\u4e2d\u4f4dOS\u67096.2\u4e2a\u6708\u7684\u5dee\u5f02\uff0c\u4f46\u7ecf\u591a\u56e0\u7d20\u5206\u6790\u548c\u77eb\u6b63\u540e\u672a\u53d1\u73b0\u7ef4\u6301\u6cbb\u7597\u53ef\u6539\u5584\u603b\u751f\u5b58\u3002<\/div>\n
3. \u5355\u836f\u7ef4\u62a4\u548c\u53cc\u836f\u7ef4\u62a4\u5728PFS\u548cOS\u4e0a\u5747\u65e0\u5dee\u5f02\u3002<\/div>\n
4. \u4e00\u7ebf\u542b\u94c2\u53cc\u836f\u65b9\u6848\u6cbb\u7597\u590d\u53d1\u8f6c\u79fb\u4e09\u9634\u6027\u4e73\u817a\u764c\u8fbe\u4e34\u5e8a\u63a7\u5236\u540e\uff0c\u5efa\u8bae\u7ee7\u7eed\u7ef4\u6301\u5316\u7597\uff0c\u4e14\u8003\u8651\u5230\u5b89\u5168\u56e0\u7d20\u4ee5\u5355\u836f\u65b9\u6848\u7ef4\u6301\u5316\u7597\u4e3a\u4f18\u5148\u9009\u62e9\u3002<\/div>\n
\u00a0<\/div>\n
\u25c6\u00a0\u6c5f\u6cfd\u98de \u6559\u6388\uff08\u89e3\u653e\u519b307\u533b\u9662\uff09<\/div>\n
\u62a5\u544a\u4e3b\u9898\uff1a\u300a\u4e73\u817a\u764cCSCOBC\u4e13\u573a\uff1a\u8fdb\u5c55\u548c\u5c55\u671b\u300b<\/div>\n
1. \u9488\u5bf9Her2\u57fa\u56e0\u7684\u9776\u5411\u6cbb\u7597\u6210\u4e3a\u628a\u63e1\u9a71\u52a8\u6301\u7eed\u6291\u5236\u6210\u529f\u8303\u4f8b\u3002<\/div>\n
2. MBC\u7684\u6297Her2\u6cbb\u7597\u5df2\u8fdb\u5165\u4e8c\u7ebf\uff08TKIs\/TDM1\uff09\u3002<\/div>\n
3. EBC\u7684\u65b0\u8f85\u52a9\/\u8f85\u52a9\u6cbb\u7597\u7597\u6548\u8fdb\u4e00\u6b65\u63d0\u9ad8\uff08H+P\uff09\u3002<\/div>\n
4. \u590d\u5236\u6cbb\u7597\u9700\u8981\u6839\u636e\u5176\u4ed6\u5371\u9669\u56e0\u7d20\u8fdb\u884c\u52a0\u51cf\u6cd5\u3002<\/div>\n
5. Her2\u7a81\u53d8\u3001\u6850\u5e90\u706b\u82b1\u6210\u4e3a\u5ba2\u670d\u8010\u836f\u7684\u65b0\u9776\u70b9\u3002<\/div>\n
\u7f16\u8005\uff1aClare\/\u8292\u679c\/Eric\/Candice\u00a0 \u00a0\u6821\u5bf9\uff1a\u5c18\u7070\u00a0 \u00a0\u5ba1\u6838\uff1aMark<\/div>\n
\u3010\u62db\u8058\u4fe1\u606f\u53d1\u5e03\u670d\u52a1\u3011\u57fa\u56e0\u6167\u73b0\u514d\u8d39\u4e3a\u79d1\u7814\u9662\u6821\u53d1\u5e03\u62db\u8058\u4fe1\u606f\uff0c\u8be6\u60c5\u8bf7\u70b9\u51fb\u57fa\u56e0\u6167\u516c\u4f17\u53f7\uff08GeneClub-1\uff09\u83dc\u5355\u680f\u6700\u53f3\u4e0b\u201c\u5408\u4f5c\u201d\u680f\u76ee\u67e5\u770b\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0 \u57fa\u56e0\u6167\u62db\u8058\u00a0\u00a0<\/div>\n
\u65b0\u5a92\u4f53\u7f16\u8f91\u3001\u884c\u4e1a\u5206\u6790\u5e08<\/div>\n
\u5408\u4f19\u4eba\u3001\u4e92\u8054\u7f51\u4ea7\u54c1\u7ecf\u7406<\/div>\n
\u6b22\u8fce\u7b80\u5386\u7838\u5411\uff1ainfo@genonet.cn<\/div>\n
\u00a0<\/div>\n
\u63a8\u8350\u680f\u76ee\u9605\u8bfb<\/div>\n
CSCO\u77ad\u671b | \u5927\u4f1a\u7b2c\u4e8c\u65e5\u514d\u75ab\u6cbb\u7597\/CDE\/\u751f\u7269\u6807\u5fd7\u7269\u7b495\u5927\u4e13\u573a\u7b14\u8bb0<\/a><\/div>\n
![\"RmFicvQBAkgA18K9eAiaJNmJ1W5dbas9nG8JRhNwxWjpiasLr67rYKfaADnYDQL1XUZaxtGB1l5Q20a8kk1pk5wwQ\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgA18K9eAiaJNmJ1W5dbas9nG8JRhNwxWjpiasLr67rYKfaADnYDQL1XUZaxtGB1l5Q20a8kk1pk5wwQ.jpeg\")
<\/figure><\/div>","protected":false},"excerpt":{"rendered":"