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href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247491455&amp;idx=1&amp;sn=2be15deada9d2f09a379094a0bd2e1a8&amp;chksm=eb72adc8dc0524de1db57c906ccf8d409525b4750e6e33cdc8eed80582ae6c6cb3b275b34059&amp;scene=21#wechat_redirect\">\u8be6\u60c5<\/a>\uff09\uff0c\u5e76\u8868\u793a\u4ece2019\u5e74\u8d77\uff0c\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u5c06\u88ab\u4f5c\u4e3a\u6807\u51c6\u4e4b\u4e00\u8f85\u52a9\u91cd\u75c5\u60a3\u513f\u3001\u60a3\u6709\u96be\u6cbb\u6108\u6216\u7f55\u89c1\u75be\u75c5\u6210\u5e74\u60a3\u8005\u7684\u6cbb\u7597\u3002\u8fd9\u6807\u5fd7\u7740\u7cbe\u51c6\u533b\u5b66\u7814\u7a76\u8fdb\u5165\u4e86\u5927\u6570\u636e\u65f6\u4ee3\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u5927\u578b\u7814\u7a76\u9879\u76ee\u5b8c\u6210\u9700\u8981\u8f83\u957f\u5468\u671f\uff0c\u9879\u76ee\u8bbe\u8ba1\u3001\u6837\u672c\u91c7\u96c6\u53ca\u57fa\u56e0\u6d4b\u5e8f\u9700\u8981\u82b1\u8d39\u5927\u91cf\u7684\u65f6\u95f4\u4e0e\u8d44\u91d1\uff0c\u5408\u7406\u5229\u7528\u5df2\u6709\u7684\u6570\u636e\u5c06\u5927\u5927\u52a0\u901f\u8fd9\u4e00\u8fdb\u7a0b\u3002\u9274\u4e8e\u6b64\uff0c\u5728\u4e25\u683c\u9075\u4ece\u300a\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u7ba1\u7406\u6682\u884c\u529e\u6cd5\u300b\u548c\u751f\u547d\u4f26\u7406\u539f\u5219\u7684\u89c4\u8303\u4e0b\uff0c\u4ee5\u53ca\u5145\u5206\u91cd\u89c6\u77e5\u60c5\u540c\u610f\u548c\u9690\u79c1\u4fdd\u62a4\u7684\u524d\u63d0\u4e0b\uff0c\u534e\u5927\u7814\u7a76\u56e2\u961f\u9009\u53d6\u4e8614\u4f59\u4e07\u65e0\u521b\u4ea7\u524d\u57fa\u56e0\u68c0\u6d4b\u6570\u636e\u5c55\u5f00\u4e86\u7fa4\u4f53\u6c34\u5e73\u7684\u7814\u7a76\uff0c\u5f00\u53d1\u4e86\u4e00\u7cfb\u5217\u9002\u7528\u4e8e\u6b64\u7c7b\u6570\u636e\u7684\u5206\u6790\u65b9\u6cd5\uff0c\u63ed\u793a\u4e86\u5305\u62ec31\u4e2a\u7701\u3001\u6c49\u65cf\u4e0e36\u4e2a\u5c11\u6570\u6c11\u65cf\u5728\u5185\u7684\u4e2d\u56fd\u4eba\u7fa4\u7cbe\u7ec6\u7684\u9057\u4f20\u7ed3\u6784\uff0c\u5b9e\u73b0\u4e86\u591a\u79cd\u8868\u578b\u7684\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u7814\u7a76\uff0c\u63ed\u793a\u4e86\u4e2d\u56fd\u4eba\u7fa4\u4e2d\u75c5\u6bd2\u5e8f\u5217\u5206\u5e03\u7279\u5f81\uff0c\u6784\u5efa\u4e86\u5305\u542b\u7ea6900\u4e07\u4e2a\u591a\u6001\u6027\u4f4d\u70b9\u7684\u708e\u9ec4\u4e2d\u56fd\u4eba\u7fa4\u57fa\u56e0\u9891\u7387\u6570\u636e\u5e93 (CMDB)\uff0c\u6700\u7ec8\u5c06\u6210\u679c\u53d1\u8868\u4e8e\u6700\u65b0\u4e00\u671f\u7684\u56fd\u9645\u9876\u7ea7\u5b66\u672f\u671f\u520a\u300a\u7ec6\u80de\u300b\u4e2d\u3002<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDXnnubgE2IsLROoCDsB6pGkeqyh5Uh9JKHW02gUm7ZicyunNIeqlWaNjr5K9upQlKcSqibEjvaf3mA.jpeg\" alt=\"RmFicvQBAkgDXnnubgE2IsLROoCDsB6pGkeqyh5Uh9JKHW02gUm7ZicyunNIeqlWaNjr5K9upQlKcSqibEjvaf3mA\"\/><\/figure><\/div>\n\n<div style=\"text-align: center;\">\u00a0\u56fe\uff0c\u300aCell\u300b\u6587\u7ae0\u622a\u56fe<\/div>\n<div>\u5f90\u8baf\u535a\u58eb\u8868\u793a\uff0c\u6b64\u6b21\u7814\u7a76\u6210\u679c\u4e0d\u4ec5\u586b\u8865\u4e86\u5927\u89c4\u6a21\u4e2d\u56fd\u4eba\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\u9886\u57df\u7684\u4f17\u591a\u7a7a\u767d\uff0c\u5e76\u8868\u660e\u65e0\u521b\u4ea7\u524d\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6570\u636e\u6216\u8005\u7c7b\u4f3c\u7684\u5168\u57fa\u56e0\u7ec4\u8d85\u4f4e\u6df1\u5ea6\u6d4b\u5e8f\u6570\u636e\u53ef\u4ee5\u6709\u6548\u5730\u7528\u4e8e\u7fa4\u4f53\u9057\u4f20\u5b66\u3001\u75be\u75c5\u4e0e\u8868\u578b\u7b49\u9886\u57df\u7684\u9ad8\u6c34\u5e73\u7814\u7a76\uff0c\u5e76\u5c06\u5728\u9057\u4f20\u75c5\u8bca\u65ad\u3001\u80bf\u7624\u7814\u7a76\u3001\u836f\u7269\u7814\u53d1\u7b49\u9886\u57df\u5f97\u5230\u5e7f\u6cdb\u7684\u5e94\u7528\u3002<\/div>\n<div>\u636e\u4e86\u89e3\uff0c\u534e\u5927\u57282016\u5e74\u6b63\u5f0f\u53d1\u8d77\u201c\u767e\u4e07\u4eba\u7fa4\u57fa\u56e0\u5927\u6570\u636e\u7814\u7a76\u201d\u9879\u76ee\uff0c\u6b64\u6b21\u7814\u7a76\u9879\u76ee\u6b63\u662f\u5176\u7b2c\u4e00\u671f\u7684\u6210\u679c\u3002\u534e\u5927\u5e0c\u671b\u901a\u8fc7\u5bf9\u767e\u4e07\u4e2d\u56fd\u4eba\u7fa4\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6570\u636e\u7684\u7efc\u5408\u7814\u7a76\uff0c\u4fc3\u8fdb\u9057\u4f20\u5b66\u7814\u7a76\u4e0e\u7cbe\u51c6\u533b\u5b66\u7684\u53d1\u5c55\uff0c\u66f4\u597d\u5730\u5b9e\u73b0\u57fa\u56e0\u79d1\u6280\u9020\u798f\u4eba\u7c7b\u7684\u613f\u666f\u4e0e\u4f7f\u547d\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u8fd9\u662f\u9ad8\u6c34\u5e73\u56fd\u9645\u5b66\u672f\u671f\u520a\u7b2c\u4e00\u6b21\u8ba4\u540c\u5728\u5176\u4e0a\u53d1\u8868\u57fa\u56e0\u7ec4\u5b66\u6587\u7ae0\u6240\u4f7f\u7528\u7684\u6570\u636e\u4ec5\u9700\u4fdd\u5b58\u4e8e\u6df1\u5733\u56fd\u5bb6\u57fa\u56e0\u5e93\uff0c\u800c\u65e0\u9700\u5411\u5883\u5916\u6570\u636e\u5e93\u8fdb\u884c\u5907\u4efd\uff0c\u8fd9\u610f\u5473\u7740\u56fd\u9645\u5b66\u672f\u671f\u520a\u5bf9\u6211\u56fd\u9057\u4f20\u8d44\u6e90\u7684\u5145\u5206\u5c0a\u91cd\u4e0e\u8ba4\u540c\uff0c\u4e5f\u4ee3\u8868\u7740\u4e2d\u56fd\u5df2\u7ecf\u5b8c\u5168\u6709\u80fd\u529b\u4e0e\u5b9e\u529b\u7ba1\u7406\u4e0e\u4fdd\u62a4\u6211\u56fd\u91cd\u8981\u7684\u9057\u4f20\u8d44\u6e90\u3002<\/div>\n<div>\u81ea2016\u5e74\u6b63\u5f0f\u8fd0\u8425\u4ee5\u6765\uff0c\u6df1\u5733\u56fd\u5bb6\u57fa\u56e0\u5e93\u5df2\u6210\u4e3a\u6211\u56fd\u751f\u7269\u9057\u4f20\u8d44\u6e90\u5b58\u50a8\u7684\u91cd\u8981\u57fa\u7840\u652f\u6491\uff0c\u4e3a\u6211\u56fd\u7684\u9057\u4f20\u8d44\u6e90\u63d0\u4f9b\u4e86\u81f3\u5173\u91cd\u8981\u7684\u4fdd\u62a4\uff0c\u8ba9\u4e2d\u56fd\u53ef\u4ee5\u5c06\u91cd\u8981\u7684\u6570\u636e\u5b58\u50a8\u4e8e\u56fd\u5185\uff0c\u800c\u65e0\u9700\u4e0a\u4f20\u81f3\u56fd\u5916\u7684\u6570\u636e\u5e93\u8fdb\u884c\u4fdd\u5b58\uff1b\u540c\u65f6\uff0c\u5728\u786e\u4fdd\u5b89\u5168\u6027\u548c\u89c4\u8303\u5316\u7684\u524d\u63d0\u4e0b\uff0c\u652f\u6301\u5bf9\u6570\u636e\u5f00\u5c55\u4e25\u8c28\u7684\u79d1\u5b66\u7814\u7a76\uff0c\u8fd9\u5bf9\u4e8e\u6211\u56fd\u7684\u57fa\u56e0\u6570\u636e\u81ea\u4e3b\u6743\u4ee5\u53ca\u884c\u4e1a\u53d1\u5c55\u90fd\u5177\u6709\u975e\u5e38\u91cd\u8981\u7684\u6218\u7565\u610f\u4e49\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u9996\u6b21\u63ed\u79d8\u4e2d\u56fd\u4eba\u7fa4\u57fa\u56e0\u9057\u4f20\u7279\u5f81<\/div>\n<div>\u534e\u5927\u7684\u7814\u7a76\u5c0f\u7ec4\u4e3b\u8981\u4ece\u4e2d\u56fd\u4eba\u7fa4\u4f53\u9057\u4f20\u5b66\u3001\u590d\u6742\u6027\u72b6\u7684\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u5206\u6790\u3001\u4e2d\u56fd\u4eba\u75c5\u6bd2\u611f\u67d3\u56fe\u8c31\u7b49\u4e09\u4e2a\u65b9\u9762\u63ed\u79d8\u4e2d\u56fd\u4eba\u7fa4\u4f53\u4e2d\u7684\u751f\u7269\u5927\u53d1\u73b0\u3002<\/div>\n<div>1\uff09\u63ed\u793a\u4e2d\u56fd\u5357\u5317\u65b9\u9057\u4f20\u5dee\u5f02<\/div>\n<div>\u867d\u7136\u6211\u56fd\u4eba\u53e3\u4f17\u591a\uff0c\u5386\u53f2\u60a0\u4e45\uff0c\u4f46\u957f\u4e45\u4ee5\u6765\uff0c\u7531\u4e8e\u5b9e\u9a8c\u7814\u7a76\u62bd\u6837\u4e0d\u5145\u5206\uff0c\u5bfc\u81f4\u6211\u4eec\u5bf9\u81ea\u8eab\u7684\u9057\u4f20\u7279\u5f81\u8ba4\u8bc6\u4e0d\u591a\u3002\u901a\u8fc7\u5927\u6570\u636e\u5206\u6790\uff0c\u7814\u7a76\u5c0f\u7ec4\u786e\u5b9a\u4e866\u4e2a\u5728\u5730\u533a\u7eac\u5ea6\u65b9\u5411\u4e0a\u53d7\u5230\u5f3a\u70c8\u81ea\u7136\u9009\u62e9\u7684\u57fa\u56e0\uff0c\u5b83\u4eec\u5728\u57fa\u56e0\u9891\u7387\u4e0a\u5448\u73b0\u660e\u663e\u7684\u5357\u5317\u5dee\u5f02\uff0c\u5145\u5206\u5c55\u73b0\u4e86\u996e\u98df\u3001\u6c14\u5019\u3001\u75c5\u539f\u4f53\u7b49\u73af\u5883\u56e0\u7d20\u5bf9\u4e2d\u56fd\u4eba\u7fa4\u7684\u6f14\u5316\u6240\u8d77\u5230\u7684\u9009\u62e9\u4f5c\u7528\uff0c\u8fd9\u662f\u79d1\u5b66\u5bb6\u7b2c\u4e00\u6b21\u80fd\u591f\u5728\u4e2d\u56fd\u4eba\u7fa4\u4f53\u4e2d\u8fdb\u884c\u5982\u6b64\u7cbe\u7ec6\u5316\u7684\u7814\u7a76\u548c\u5bf9\u6bd4\u3002<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDXnnubgE2IsLROoCDsB6pGvz7WHUajUdkIubcorhpBewAaUlayrgiaibXD3lcyL4gvLA0icC3ChFUcQ.jpeg\" alt=\"RmFicvQBAkgDXnnubgE2IsLROoCDsB6pGvz7WHUajUdkIubcorhpBewAaUlayrgiaibXD3lcyL4gvLA0icC3ChFUcQ\"\/><\/figure><\/div>\n\n<div style=\"text-align: center;\">\u56fe\uff0c6\u4e2a\u5728\u4e2d\u56fd\u53d7\u5230\u663e\u8457\u81ea\u7136\u9009\u62e9\u7684\u57fa\u56e0\u4f4d\u70b9<\/div>\n<div>\u540c\u65f6\uff0c\u7814\u7a76\u5c0f\u7ec4\u901a\u8fc7\u5206\u6790\u4eba\u7fa4\u9057\u4f20\u8ddd\u79bb\u7684\u53d8\u5316\u548c\u57fa\u56e0\u6d41\u65b9\u5411\uff0c\u63ed\u793a\u4e86\u6c49\u65cf\u4e0e\u5c11\u6570\u6c11\u65cf\u7fa4\u4f53\u7684\u9057\u4f20\u7ed3\u6784\u7279\u70b9\u53ca\u4e2d\u56fd\u5404\u7701\u4e0e\u6b27\u6d32\u3001\u5357\u4e9a\u3001\u4e1c\u4e9a\u4eba\u7fa4\u7684\u57fa\u56e0\u4ea4\u6d41\u7a0b\u5ea6\uff08\u6216\u8005\u8bf4\u662f\u901a\u5a5a\u7a0b\u5ea6\uff09\uff0c\u53d1\u73b0\u5f53\u4eca\u4e2d\u56fd\u4eba\u7684\u9057\u4f20\u7279\u70b9\u540c\u65f6\u53d7\u5230\u4e1d\u7ef8\u4e4b\u8def\u53ca\u8fd1\u4ee3\u4eba\u53e3\u5927\u89c4\u6a21\u8fc1\u5f99\u7b49\u56e0\u7d20\u7684\u591a\u91cd\u5f71\u54cd\u3002<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDXnnubgE2IsLROoCDsB6pGQl7NibfAwpPlsTReCibcZkIicEwJXaDictf0ZTI9bW5Qibj4TLa351kCuSg.jpeg\" alt=\"RmFicvQBAkgDXnnubgE2IsLROoCDsB6pGQl7NibfAwpPlsTReCibcZkIicEwJXaDictf0ZTI9bW5Qibj4TLa351kCuSg\"\/><\/figure><\/div>\n\n<div style=\"text-align: center;\">\u56fe\uff0c\u5404\u7701\u5168\u4f53\u4e2d\u56fd\u4eba\uff08\u5de6\uff09\u548c\u5404\u7701\u6c49\u65cf\u4eba\uff08\u53f3\uff09\u6240\u542b\u6709\u7684\u6b27\u6d32\u4eba\u6210\u5206\u5206\u5e03<\/div>\n<div>2\uff09\u91cd\u8981\u8868\u578b\u7684\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u5206\u6790<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDXnnubgE2IsLROoCDsB6pGk2cE424YgCvUWY0lCdKOwzwNCDOXOaUHWTibDcAZsB1RZQO7Wia7IiaaA.jpeg\" alt=\"RmFicvQBAkgDXnnubgE2IsLROoCDsB6pGk2cE424YgCvUWY0lCdKOwzwNCDOXOaUHWTibDcAZsB1RZQO7Wia7IiaaA\"\/><\/figure><\/div>\n\n<div style=\"text-align: center;\">\u56fe\uff0c\u56db\u4e2a\u91cd\u8981\u8868\u578b\uff08\u8eab\u9ad8\u3001BMI\u3001\u6000\u5b55\u5e74\u9f84\u3001\u53cc\u80ce\u6000\u5b55\uff09\u7684GWAS\u7814\u7a76<\/div>\n<div>\u6b64\u5916\uff0c\u7814\u7a76\u5c0f\u7ec4\u9996\u6b21\u57fa\u4e8e\u8fd9\u7c7b\u8d85\u4f4e\u6df1\u5ea6\u6d4b\u5e8f\u6570\u636e\u5bf9\u4e2d\u56fd\u4eba\u7fa4\u4e2d\u76844\u79cd\u91cd\u8981\u8868\u578b\u8fdb\u884c\u4e86\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u7814\u7a76\uff08GWAS\uff09\u3002<\/div>\n<div>\u901a\u8fc7\u6570\u636e\u5206\u6790\uff0c\u7814\u7a76\u5c0f\u7ec4\u4e00\u6b21\u6027\u53d1\u73b0\u5e76\u4e14\u9a8c\u8bc1\u4e8648\u4e2a\u4e0e\u8eab\u9ad8\u4ee5\u53ca13\u4e2a\u4e0e\u8eab\u4f53\u8d28\u91cf\u6307\u6570(\u4ee5\u4e0b\u7edf\u79f0BMI)\u663e\u8457\u76f8\u5173\u7684\u57fa\u56e0\u4f4d\u70b9\uff0c\u5305\u62ec\u8fd9\u4e9b\u4f4d\u70b9\u5728\u5185\u7684\u5e38\u89c1\u7a81\u53d8\u4f4d\u70b9\u5206\u522b\u89e3\u91ca\u4e8648%\u7684\u8eab\u9ad8\u9057\u4f20\u7387\u4ee5\u53ca10%\u7684BMI\u9057\u4f20\u7387\u3002\u968f\u7740\u7814\u7a76\u7684\u8fdb\u4e00\u6b65\u6df1\u5165\uff0c\u79d1\u5b66\u5bb6\u548c\u7b97\u6cd5\u5de5\u7a0b\u5e08\u6709\u53ef\u80fd\u53ef\u4ee5\u5229\u7528\u8fd9\u4e9b\u4fe1\u606f\u6784\u5efa\u4e00\u5957\u9002\u5408\u4e8e\u4e2d\u56fd\u4eba\u7684\u8eab\u9ad8\u9884\u6d4b\u6a21\u578b\uff0c\u901a\u8fc7\u57fa\u56e0\u6570\u636e\u63a8\u65ad\u51fa\u4e2a\u4eba\u7684\u8eab\u9ad8\u60c5\u51b5\u3002<\/div>\n<div>\u53e6\u5916\uff0c\u7814\u7a76\u5c0f\u7ec4\u5bf9\u6000\u5b55\u5e74\u9f84\u548c\u53cc\u80ce\u6000\u5b55\u4e24\u4e2a\u8868\u578b\u8fdb\u884c\u4e86\u6df1\u5165\u7814\u7a76\uff0c\u53d1\u73b0\u4e86\u4e24\u4e2a\u4e0e\u6000\u5b55\u5e74\u9f84\u663e\u8457\u76f8\u5173\u7684\u57fa\u56e0\u4f4d\u70b9\uff0c\u6697\u793a\u7740\u8fd9\u4e24\u4e2a\u4f4d\u70b9\u7684\u7a81\u53d8\u4e0e\u751f\u80b2\u529b\u5bc6\u5207\u5173\u8054\uff1b\u4e0e\u6b64\u540c\u65f6\uff0c\u8fd8\u5728NRG1\u57fa\u56e0\u4e2d\u53d1\u73b0\u4e86\u4e00\u4e2a\u548c\u53cc\u80de\u80ce\u598a\u5a20\u663e\u8457\u76f8\u5173\u7684\u7a81\u53d8\u4f4d\u70b9\uff0c\u4e5f\u5c31\u8bf4\u643a\u5e26\u6709NRG1\u57fa\u56e0\u7279\u5b9a\u7a81\u53d8\u7684\u5b55\u5987\uff0c\u6709\u66f4\u9ad8\u7684\u51e0\u7387\u6000\u4e0a\u53cc\u80de\u80ce\u3002<\/div>\n<div>\u00a0<\/div>\n<div>3\uff09\u9996\u6b21\u63ed\u793a\u4e2d\u56fd\u4eba\u75c5\u6bd2\u56fe\u8c31\u00a0 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aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDXnnubgE2IsLROoCDsB6pG6wj58EHwsWvK9hh1cAhvng0omgC7zIO2iaYWNAiarzIXb5n4mQcUD63Q.jpeg\" alt=\"RmFicvQBAkgDXnnubgE2IsLROoCDsB6pG6wj58EHwsWvK9hh1cAhvng0omgC7zIO2iaYWNAiarzIXb5n4mQcUD63Q\"\/><\/figure><\/div>\n\n<div style=\"text-align: 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