{"id":9356,"date":"2018-11-09T13:31:49","date_gmt":"2018-11-09T05:31:49","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100008172&idx=1&sn=3761266a6d5d300dc52642a1c61cb095&chksm=6b71525b5c06db4d46c2c671999ac8f72035f3c6287833a4a2404101e715ea721e33590791f7#rd"},"modified":"2026-04-02T16:10:23","modified_gmt":"2026-04-02T08:10:23","slug":"1005597","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2018\/11\/09\/1005597\/","title":{"rendered":"GeneMail\u5468\u62a5 | \u8d1d\u745e\u57fa\u56e0\u8fdb\u519b\u6d88\u8d39\u7ea7\u57fa\u56e0\u68c0\u6d4b\uff1bctDNA\u7247\u6bb5\u5927\u5c0f\u7279\u5f81\u68c0\u6d4b\u65e9\u671f\u764c\u75c7"},"content":{"rendered":"

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\u6587\/\u57fa\u56e0\u6167<\/div>\n
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\n
\"?wx_fmt=jpeg\"\/<\/figure><\/div>\n\n
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\u00a0<\/div>\n
\u672c\u5468\u5934\u6761<\/div>\n
\u25bc \u8d1d\u745e\u57fa\u56e0\u8fdb\u519b\u6d88\u8d39\u7ea7\u57fa\u56e0\u68c0\u6d4b<\/div>\n\n
\n
\"RmFicvQBAkgAicT2s4p07iaBhibO0hzUKgNa9EulrCUdwh6JialZUoicVUQicvcib6uInicQE3icszGVtcFo0C04pADzKYiag\"\/<\/figure><\/div>\n\n
11\u67089\u65e5\u6d88\u606f\uff0c\u8d1d\u745e\u57fa\u56e0\u4e0e\u603b\u90e8\u4f4d\u4e8e\u9999\u6e2f\u7684Prenetics\u5408\u4f5c\uff0c\u4e24\u5bb6\u4f01\u4e1a\u5c06\u6210\u7acb\u4e00\u5bb6\u5408\u8d44\u4f01\u4e1a\uff0c\u9762\u5411\u4e2d\u56fd\u5e02\u573a\u63a8\u51fa\u76f4\u63a5\u9762\u5411\u6d88\u8d39\u8005\uff08DTC\uff09\u7684\u57fa\u56e0\u68c0\u6d4b\u670d\u52a1\u3002\u8fd9\u4e9bDTC\u4ea7\u54c1\u5c06\u4e8e2019\u5e74\u7b2c\u4e00\u5b63\u5ea6\u5f00\u59cb\u5728\u7ebf\u8ba2\u8d2d\u3002\u8be5\u5408\u8d44\u4f01\u4e1a\u5c06\u5bfb\u6c42\u4e0e\u4fdd\u9669\u516c\u53f8\u3001\u653f\u5e9c\u7b49\u4e3b\u8981\u5229\u76ca\u76f8\u5173\u65b9\u8fdb\u884c\u5408\u4f5c\uff0c\u52a0\u5feb\u5f00\u62d3\u5e02\u573a\u3002Prenetics \u5728\u4eca\u5e74\u4ee51000\u4e07\u7f8e\u5143\u7684\u4ef7\u683c\u6536\u8d2d\u4e86\u82f1\u56fd\u6d88\u8d39\u7ea7\u57fa\u56e0\u68c0\u6d4b\u516c\u53f8DNAFit\uff08\u4e86\u89e3DNAFit<\/a>\uff09\uff0c\u6807\u5fd7\u7740\u5176\u8fdb\u5165\u6d88\u8d39\u7ea7\u57fa\u56e0\u7ec4\u5b66\u9886\u57df\u7684\u7b2c\u4e00\u6b65\u3002<\/div>\n
\u00a0<\/div>\n
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\u00a0<\/div>\n
\u653f\u7b56<\/div>\n
\u25bc \u533b\u836f\u5668\u68b0<\/div>\n
\u4e0a\u6d77\u63a8\u51fa\u201c\u9f13\u52b1\u836f\u68b0\u521b\u65b032\u6761\u201d\uff0c\u5efa\u8bbe\u751f\u7269\u533b\u836f\u521b\u65b0\u7814\u53d1\u9ad8\u5730<\/div>\n
11\u67087\u65e5\uff0c\u4e0a\u6d77\u5e02\u59d4\u529e\u516c\u5385\u3001\u5e02\u653f\u5e9c\u529e\u516c\u5385\u53d1\u5e03\u300a\u5173\u4e8e\u6df1\u5316\u5ba1\u8bc4\u5ba1\u6279\u5236\u5ea6\u6539\u9769\u9f13\u52b1\u836f\u54c1\u533b\u7597\u5668\u68b0\u521b\u65b0\u7684\u5b9e\u65bd\u610f\u89c1\u300b\uff0c\u63d0\u51fa32\u6761\u5177\u4f53\u4e3e\u63aa\uff0c\u529b\u4e89\u4f7f\u672c\u5e02\u4e34\u5e8a\u8bd5\u9a8c\u673a\u6784\u6570\u91cf\u8fbe\u523080\u5bb6\u4ee5\u4e0a\u3001\u529b\u4e89\u96c6\u805a20\u5bb6\u4ee5\u4e0a\u5177\u6709\u56fd\u9645\u5f71\u54cd\u529b\u7684\u751f\u7269\u533b\u836f\u521b\u65b0\u7814\u53d1\u4e2d\u5fc3\u3001\u4e89\u53d6\u6bcf\u5e74\u670930\u4e2a\u4ee5\u4e0a\u5177\u6709\u6838\u5fc3\u6280\u672f\u4f18\u52bf\u7684\u81ea\u4e3b\u521b\u65b0\u836f\u54c1\u533b\u7597\u5668\u68b0\u4ea7\u54c1\u6ce8\u518c\u7533\u62a5\u3002<\/div>\n
\u00a0<\/div>\n
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\u5168\u56fd\u51fa\u751f\u7f3a\u9677\u9632\u6cbb\u4eba\u624d\u57f9\u8bad\u9879\u76ee\u57f9\u8bad\u5927\u7eb2\u53d1\u5e03<\/div>\n
10\u670831\u65e5\uff0c\u56fd\u5bb6\u536b\u5065\u59d4\u5987\u5e7c\u53f8\u53d1\u5e03\u300a\u5168\u56fd\u51fa\u751f\u7f3a\u9677\u9632\u6cbb\u4eba\u624d\u57f9\u8bad\u9879\u76ee\u57f9\u8bad\u5927\u7eb2\uff08\u8bd5\u884c\uff09\u300b\uff0c\u65e8\u5728\u843d\u5b9e\u5168\u56fd\u51fa\u751f\u7f3a\u9677\u9632\u6cbb\u4eba\u624d\u57f9\u8bad\u9879\u76ee\u65b9\u6848\uff0c\u63d0\u9ad8\u4e13\u4e1a\u4eba\u5458\u57f9\u8bad\u7684\u7cfb\u7edf\u6027\u548c\u89c4\u8303\u6027\uff0c\u4fc3\u8fdb\u9879\u76ee\u987a\u5229\u5b9e\u65bd\uff0c\u6307\u5bfc\u9879\u76ee\u5730\u533a\u89c4\u8303\u6709\u5e8f\u5f00\u5c55\u540c\u8d28\u5316\u57f9\u8bad\u3002<\/div>\n
\u00a0<\/div>\n
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\u56fd\u5bb6\u536b\u5065\u59d4\u53d1\u5e03\u6539\u5584\u533b\u7597\u670d\u52a1\u884c\u52a8\u8ba1\u5212\u8003\u6838\u6307\u6807<\/div>\n
10\u670831\u65e5\uff0c\u56fd\u5bb6\u536b\u5065\u59d4\u53d1\u5e03\u300a\u8fdb\u4e00\u6b65\u6539\u5584\u533b\u7597\u670d\u52a1\u884c\u52a8\u8ba1\u5212\uff082018-2020\u5e74\uff09\u8003\u6838\u6307\u6807\u300b\uff0c\u5bf9\u4e2a\u8003\u6838\u9879\u505a\u51fa\u5177\u4f53\u6307\u6807\u8981\u6c42\u3002\u9996\u6b21\u52a0\u5165\u8fdc\u7a0b\u533b\u7597\u548c\u591a\u5b66\u79d1\u8bca\u7597\u6a21\u5f0f \uff0c\u5206\u522b\u5360\u8003\u6838\u6bd4\u52068\u5206\uff0c\u5747\u4e3a\u5b9a\u6027\u8003\u6838\u6307\u6807\uff0c\u9700\u4e13\u5bb6\u8bc4\u5ba1\u3002\u201c\u667a\u6167\u533b\u9662\u201d\u8003\u6838\u5360\u6bd4\u9ad8\u8fbe14%\u3002<\/div>\n
\u00a0<\/div>\n
\u25bc \u5173\u952e\u8bcd\uff1a\u4e34\u5e8a\u8bd5\u9a8c\u6539\u9769<\/div>\n
CDE\u516c\u793a8\u4e2a\u4e34\u5e8a\u5907\u6848\uff0c\u5f00\u542f\u9ed8\u793a\u8bb8\u53ef\u65f6\u4ee3<\/div>\n
11\u67085\u65e5\uff0c\u56fd\u5bb6\u836f\u76d1\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u5b98\u7f51\u4e3b\u9875\u70ed\u70b9\u680f\u76ee\u4e2d\uff0c\u51fa\u73b0\u201c\u4e34\u5e8a\u8bd5\u9a8c\u9ed8\u793a\u8bb8\u53ef\u516c\u793a\u201d\uff0c\u6807\u5fd7\u7740\u4e2d\u56fd\u6b63\u5f0f\u5bf9\u65b0\u836f\u4e34\u5e8a\u8bd5\u9a8c\u7531\u8fc7\u53bb\u7684\u5ba1\u6279\u5236\u6539\u9769\u4e3a\u9ed8\u793a\u8bb8\u53ef\uff0c\u76ee\u524d\u5df2\u67098\u4e2a\u53d7\u7406\u53f7\u83b7\u5f97\u9ed8\u8bb8\uff0c\u88ab\u9996\u6279\u516c\u793a\uff0c\u6765\u81ea\u9ed8\u6c99\u4e1c\u3001\u827e\u4f2f\u7ef4\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u79d1\u7814<\/div>\n
\u25bc \u5173\u952e\u8bcd\uff1a\u6db2\u4f53\u6d3b\u68c0<\/div>\n
\u5faa\u73af\u80bf\u7624DNA\u7247\u6bb5\u5927\u5c0f\u7279\u5f81\u53ef\u4ee5\u68c0\u6d4b\u65e9\u671f\u764c\u75c7<\/div>\n
11\u67088\u65e5\u300aScience Translational Medicine\u300b\u520a\u6587\uff0c\u82f1\u56fd\u5251\u6865\u5927\u5b66\u79d1\u5b66\u5bb6\u9886\u5bfc\u7684\u7814\u7a76\u56e2\u961f\u53d1\u73b0ctDNA\u5927\u5c0f\u7279\u5f81\u53ef\u4ee5\u52a9\u529b\u68c0\u6d4b\u65e9\u671f\u764c\u75c7\u3002\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u80bf\u7624DNA\u7247\u6bb5\u5f80\u5f80\u6bd4\u8840\u6db2\u4e2d\u5176\u4ed6DNA\u7247\u6bb5\u5c0f\uff0c\u4f9d\u636e\u8fd9\u4e00\u70b9\u5efa\u7acb\u4e86\u5ea6\u91cf\u6307\u6807\u53ef\u4ee5\u5bf9DNA\u7247\u6bb5\u8fdb\u884c\u533a\u5206\uff0c\u5bf9\u764c\u75c7\u60a3\u8005\u8840\u6db2\u68c0\u6d4b\u540e\u53d1\u73b0\u4e73\u817a\u764c\u3001\u80a0\u764c\u3001\u5375\u5de2\u764c\u3001\u76ae\u80a4\u764c\u7b49\u8bef\u62a5\u7387\u4ec5\u4e3a2.5\uff05\u3002<\/div>\n
\u00a0<\/div>\n
\u25bc \u5173\u952e\u8bcd\uff1a\u57fa\u56e0\u7f16\u8f91<\/div>\n
David Liu\u56e2\u961f\u65b0\u53d1\u73b0\uff1a\u65e0\u6a21\u677fCRISPR-Cas9\u57fa\u56e0\u7f16\u8f91<\/div>\n
11\u67088\u65e5\uff0cMIT\u3001\u54c8\u4f5b\u533b\u5b66\u9662\u4ee5\u53caBroad\u7814\u7a76\u6240\u7814\u7a76\u56e2\u961f\uff08Richard Shermood\u3001David K. Gifford\u548cDavid r.Liu\u5408\u4f5c\u7ec4\uff09\u5728\u300aNature\u300b\u53d1\u8868CRISPR-Cas9\u6700\u65b0\u7814\u7a76\uff0c\u4ed6\u4eec\u5f00\u53d1\u4e86\u4e00\u79cd\u673a\u5668\u5b66\u4e60\u6a21\u578b\uff0c\u5b9e\u73b0\u4e86\u5bf9\u81f4\u75c5\u57fa\u56e0\u53d8\u5f02\u53ef\u9884\u6d4b\u3001\u7cbe\u51c6\u3001\u65e0\u6a21\u677fCRISPR-Cas9\u7f16\u8f91\uff0c\u4e3a\u9057\u4f20\u75be\u75c5\u7684\u6cbb\u7597\u63d0\u4f9b\u4e86\u65b0\u7684\u53ef\u80fd\u6027\u3002<\/div>\n
\u00a0<\/div>\n
\u25bc \u5173\u952e\u8bcd\uff1a\u957f\u5bff\u4e0e\u9057\u4f20\u56e0\u7d20<\/div>\n
\u8d854\u4ebf\u4eba\u5bb6\u7cfb\u7814\u7a76\u8bc1\u5b9e\u9057\u4f20\u56e0\u7d20\u5bf9\u4eba\u7c7b\u5bff\u547d\u5f71\u54cd\u6709\u9650<\/div>\n
11\u67082\u65e5\uff0c\u79d1\u5b66\u5bb6\u901a\u8fc7\u5bf9\u8d85\u8fc74\u4ebf\u4eba\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\u53d1\u73b0\u9057\u4f20\u56e0\u7d20\u5bf9\u5bff\u547d\u7684\u5f71\u54cd\u8fdc\u5c0f\u4e8e\u9884\u671f\uff0c\u7814\u7a76\u53d1\u8868\u5728\u300aGENETICS\u300b\u3002\u7814\u7a76\u53d1\u73b0\u914d\u5076\u7684\u5bff\u547d\u5f80\u5f80\u662f\u76f8\u5173\u7684\uff0c\u5144\u59b9\u7684\u5bff\u547d\u662f\u76f8\u5173\u7684\uff0c\u79d1\u5b66\u5bb6\u5206\u6790\u53d1\u73b0\u9057\u4f20\u56e0\u7d20\u5bf9\u5bff\u547d\u5f71\u54cd\u4e0d\u8d85\u8fc77%\uff0c\u751a\u81f3\u66f4\u4f4e\u3002<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a<\/div>\n
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11\u67081\u65e5\uff0c\u5730\u7403\u751f\u7269\u57fa\u56e0\u7ec4\u8ba1\u5212\uff08\u7b80\u79f0EBP\uff09\u5728\u82f1\u56fd\u4f26\u6566\u542f\u52a8\uff0c\u8ba1\u5212\u572810\u5e74\u5185\u5bf9\u5730\u7403\u4e0a\u6240\u6709150\u4e07\u79cd\u5df2\u77e5\u771f\u6838\u751f\u7269\u7684\u57fa\u56e0\u7ec4\u8fdb\u884c\u6d4b\u5e8f\u3001\u7f16\u76ee\u548c\u5206\u7c7b\uff0c\u9884\u8ba1\u8017\u8d4447\u4ebf\u7f8e\u5143\u3002\u9884\u8ba1\u8be5\u9879\u76ee\u5c06\u4e3a\u63a8\u8fdb\u4fdd\u62a4\u751f\u7269\u591a\u6837\u6027\u548c\u7ef4\u6301\u4eba\u7c7b\u793e\u4f1a\u53ef\u6301\u7eed\u53d1\u5c55\u521b\u9020\u4e00\u4e2a\u65b0\u57fa\u7840\u3002<\/div>\n
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\u25bc \u5173\u952e\u8bcd\uff1a\u5408\u4f5c<\/div>\n
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11\u67085\u65e5\uff0c\u5236\u836f\u5de8\u5934\u793c\u6765\u548cNextCure\u516c\u53f8\u5ba3\u5e03\u5408\u4f5c\u7814\u53d1\u65b0\u578b\u514d\u75ab\u80bf\u7624\u836f\u7269\uff0c\u65e8\u5728\u5229\u7528NextCure\u4e13\u6709\u7684FIND-IO\u2122\u5e73\u53f0\u53d1\u73b0\u65b0\u7684\u80bf\u7624\u9776\u70b9\uff0c\u793c\u6765\u5c06\u5411NextCure\u652f\u4ed84000\u4e07\u7f8e\u5143\uff0c\u5305\u62ec2500\u4e07\u7f8e\u5143\u9884\u4ed8\u6b3e\u548c1500\u4e07\u7f8e\u5143\u80a1\u6743\u6295\u8d44\u3002<\/div>\n
\u00a0<\/div>\n
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11\u67086\u65e5\uff0c\u817e\u8baf\u516c\u53f8\u4e0e\u7f57\u6c0f\u5236\u836f\u4e2d\u56fd\u5ba3\u5e03\u8fbe\u6210\u6218\u7565\u5408\u4f5c\uff0c\u5171\u540c\u6253\u9020\u4ee5\u60a3\u8005\u4ef7\u503c\u4e3a\u5bfc\u5411\u7684\u6570\u5b57\u5316\u533b\u7597\u5065\u5eb7\u670d\u52a1\u6a21\u5f0f\uff0c\u63a2\u7d22\u5927\u6570\u636e\u548c\u4eba\u5de5\u667a\u80fd\u6280\u672f\u5728\u533b\u7597\u884c\u4e1a\u7684\u5e94\u7528\uff0c\u63a8\u52a8\u533b\u7597\u5065\u5eb7\u4ea7\u4e1a\u6570\u5b57\u5316\u5347\u7ea7\u3002<\/div>\n
\u00a0<\/div>\n
Fred Hutchinson\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\u643a\u624b\u534e\u5927<\/div>\n
11\u6708\u521d\u6d88\u606f\uff0c\u534e\u5927\u96c6\u56e2\u4e0eFred Hutchinson\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\u7b7e\u7f72\u4e86\u8c05\u89e3\u5907\u5fd8\u5f55\uff0c\u53cc\u65b9\u5728\u57fa\u56e0\u7ec4\u5b66\u9886\u57df\u8fbe\u6210\u5408\u4f5c\uff0c\u5c06\u63a2\u7d22\u5efa\u7acb\u4e0e\u4e2d\u56fd\u548c\u975e\u6d32\u7684\u533b\u9662\u53ca\u7814\u7a76\u673a\u6784\u5408\u4f5c\u4f19\u4f34\u7684\u5173\u7cfb\u3002<\/div>\n
\u00a0<\/div>\n
\u25bc \u5173\u952e\u8bcd\uff1aCAR-T\u7597\u6cd5<\/div>\n
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\u00a0<\/div>\n
\u878d\u8d44<\/div>\n\n
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\u4f1a\u8bae\u9884\u544a<\/div>\n
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\u4e3b\u529e\u5355\u4f4d\uff1aIllumina<\/div>\n
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2018\u5e74\u4eac\u6d25\u5180\u533b\u5b66\u9057\u4f20\u5b66\u8bb2\u4e60\u73ed\uff08\u8be6\u60c5<\/a>\uff09<\/div>\n
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\u7f16\u8005\uff1aCandice\u00a0 \u6821\u5bf9\uff1aEric\u00a0 \u00a0\u5ba1\u6838\uff1aMark<\/div>\n
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