{"id":9294,"date":"2019-04-10T12:48:52","date_gmt":"2019-04-10T04:48:52","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100009949&idx=1&sn=ef214c898b0b2b9e6539f65136432e65&chksm=6b71556a5c06dc7c8757c729996d7c1822617e2f1c58a19b7577f06da5e2a3bf6a6d32fc4f2d#rd"},"modified":"2026-04-08T10:25:56","modified_gmt":"2026-04-08T02:25:56","slug":"5410154-3","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2019\/04\/10\/5410154-3\/","title":{"rendered":"\u5168\u7403\u6700\u5927\u7684\u764c\u75c7\u7814\u7a76\u5e74\u4f1aAACR\u8981\u70b9\u53ca\u4e2d\u56fd\u58f0\u97f3"},"content":{"rendered":"

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\"RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg\"\/<\/figure><\/div>\n\n<\/div>\n
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\u5173\u952e\u8bcd\/\u80bf\u7624 AACR \u6587\/\u8305\u77db \u7f16\u8f91\/\u57fa\u56e0\u6167<\/div>\n
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\"RmFicvQBAkgAlIJU42QUicsNDFbNp5WkYGyb5VOicxInEpPqZDS9c2BiacOBianFWf6nFxUUzsz2JMW1LoEfkiaicWmrw\"\/<\/figure><\/div>\n\n
\u56fe\uff0cAACR 2019\u4f1a\u8bae\u6d77\u62a5\uff0c\u6765\u81eaAACR\u5b98\u7f51<\/div>\n
\u5212\u91cd\u70b9<\/div>\n
1\uff09\u764c\u75c7\u65e9\u7b5b\u4f5c\u4e3a\u7f8e\u56fd\u56fd\u5bb6\u653f\u7b56\u91cd\u70b9\u3002<\/div>\n
2\uff09\u764c\u75c7\u65e9\u7b5b\u8bc6\u522b\u566a\u97f3\u53d6\u5f97\u8fdb\u5c55\u3002<\/div>\n
3\uff09\u5728ctDNA\u3001CTC\u548c\u5916\u6ccc\u4f53\uff0c\u8840\u6d46\u3001\u5c3f\u6db2\u548c\u553e\u6db2\u4e0d\u540c\u7ef4\u5ea6\u63a2\u7d22\u764c\u75c7\u65e9\u7b5b\u3002<\/div>\n
4\uff09\u764c\u75c7\u65e9\u7b5b\u8981\u770b\u5230\u771f\u5b9e\u4e16\u754c\u91cc\u5927\u89c4\u6a21\u9a8c\u8bc1\u7ed3\u679c\uff0c\u6216\u518d\u7b49\u4e0a\u4e00\u5e74\u3002\u00a0<\/div>\n
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\u00a0<\/div>\n
AACR\u5e74\u4f1a\u5438\u5f15\u4eba\u7684\u5730\u65b9\uff0c\u662f\u7ed9\u6211\u4eec\u5e26\u6765\u8fc7\u53bb\u4e00\u5230\u4e24\u5e74\u80bf\u7624\u7814\u7a76\u548c\u8bca\u7597\u7684\u65b0\u8fdb\u5c55\uff0c\u540c\u65f6\u4e5f\u5c55\u793a\u4e86\u4e0d\u8fdc\u7684\u672a\u6765\u524d\u6cbf\u7684\u79d1\u7814\u548c\u4ea7\u4e1a\u65b9\u5411\u3002\u00a0<\/div>\n
AACR\u4f1a\u8bae\u7684\u89c4\u6a21\u5f88\u5927\uff0c\u53c2\u4f1a\u8005\u8fbe21000\u4eba\uff0c\u51e0\u767e\u573a\u8ba8\u8bba\uff0c\u51e0\u5343\u4e2a\u6d77\u62a5\uff0c\u6bcf\u4e2a\u4eba\u80fdcover\u7684\u8303\u56f4\u6709\u9650\u3002\u4f1a\u8bae\u5f00\u5e55\u5f0f\u662f\u6bd4\u8f83\u6d53\u7f29\u7684\u7248\u672c\uff0c\u8fd9\u91cc\u91cd\u70b9\u548c\u5927\u5bb6\u5206\u4eab\u4e0b\u5f00\u5e55\u5f0f<\/a>\uff0c\u5305\u62ec\u80bf\u7624\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u548c\u5927\u5bb6\u7684\u5173\u6ce8\u70b9\u3002<\/div>\n
\u00a0<\/div>\n
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1.\u764c\u75c7\u65e9\u7b5b\u4f5c\u4e3a\u7f8e\u56fd\u56fd\u5bb6\u653f\u7b56\u91cd\u70b9<\/div>\n\n
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\"0?wx_fmt=jpeg\"\/<\/figure><\/div>\n\n
\u56fe\uff0cSharpless\u535a\u58eb\u3002\u6765\u81ea\u7f51\u7edc<\/div>\n
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\u00a0<\/div>\n
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\n
\"RmFicvQBAkgCiaGgxGjCFehIEWiaOby7dO4VYNtp8YZPZ0YEwYCsvkzK5hOOLqqiboAiaHLicRF8q2A0BN6iat3Y4A9LQ\"\/<\/figure><\/div>\n\n
\u56fe\uff0cPeter Kuhn\u535a\u58eb\u3002\u6765\u81eaAACR\u5b98\u7f51<\/div>\n
Peter Kuhn\u535a\u58eb\u5728\u6f14\u8bb2\u4e2d\u8c08\u5230\uff0c\u57fa\u4e8e\u53ef\u7a7f\u6234\u7684\u8bbe\u5907\u6536\u96c6\u4e34\u5e8a\u8868\u73b0\u6570\u636e\uff0c\u66f4\u597d\u7684\u6765\u505a\u764c\u75c7\u75c5\u4eba\u6cbb\u7597\u7684\u7ba1\u7406\uff0c\u4f7f\u5f97\u6cbb\u7597\u80fd\u591f\u66f4\u4e3a\u6709\u6548\uff0c\u8fd9\u4e5f\u53ef\u4ee5\u8bf4\u662f\u7b2c\u4e00\u6b21\u628a\u53ef\u7a7f\u6234\u8bbe\u5907\u5728\u764c\u75c7\u6cbb\u7597\u4e2d\u7684\u5e94\u7528\u63d0\u5230\u8fd9\u6837\u7684\u4e00\u4e2a\u9ad8\u5ea6\u3002\uff08\u7f16\u8005\u6ce8\uff1a\u53ef\u7a7f\u6234\u8bbe\u5907\u9879\u76ee\u540dATOM-HP\uff0c\u5b75\u5316\u81eaUSC\uff0c\u6536\u96c6\u4e34\u5e8a\u8868\u73b0\u6570\u636e\u91cf\u5316ECOG\u8bc4\u5206\uff09<\/div>\n
\u00a0<\/div>\n
3.\u514d\u75ab\u6cbb\u7597\u7684\u91cd\u70b9\u662f\u6709\u6548\u6027\u548c\u8010\u836f\u7684\u673a\u5236<\/div>\n
\u8fd9\u6b21\u4f1a\u8bae\u6700\u5927\u7684\u70ed\u70b9\u4f9d\u7136\u662f\u764c\u75c7\u514d\u75ab\u6cbb\u7597\uff0c\u867d\u7136\u8fd9\u4e2a\u8bdd\u9898\u5e76\u4e0d\u65b0\uff0c\u4f46\u662f\u4ece\u6240\u5c55\u793a\u7684\u7ed3\u679c\u6765\u770b\uff0c\u6211\u4eec\u5bf9\u80bf\u7624\u7684\u514d\u75ab\u6cbb\u7597\u6709\u4e86\u66f4\u591a\u7684\u65b9\u6cd5\u4ee5\u53ca\u66f4\u5168\u9762\u7684\u8ba4\u8bc6\u3002\u5728\u7814\u7a76\u65b9\u9762\uff0c\u91cd\u70b9\u662f\u514d\u75ab\u6cbb\u7597\u7684\u6709\u6548\u6027\u548c\u8010\u836f\u7684\u673a\u5236\u3002<\/div>\n
\u6765\u81ea\u4e8e\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66\u7684John Wherry\u5728T\u7ec6\u80de\u548c\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u7684\u53cd\u5e94\u6027\u4e0a\u9762\u505a\u4e86\u4e00\u4e2a\u975e\u5e38\u7cbe\u5f69\u3001\u4f18\u96c5\u5730\u6f14\u8bb2\uff0c\u5145\u5206\u5c55\u793a\u4e86\u514d\u75ab\u6cbb\u7597\u6709\u6548\u6027\u548c\u590d\u6742\u6027\uff0c\u8fd9\u91cc\u9762\u4e5f\u5305\u62ec\u8010\u836f\u6027\uff0c\u4f7f\u5f97\u6211\u4eec\u5728\u672a\u6765\u7684\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u65b9\u9762\u9700\u8981\u53bb\u770b\u66f4\u591a\u7684\u7ef4\u5ea6\u3002<\/div>\n
\u00a0<\/div>\n
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\u6bcf\u4e00\u6b21\u548c\u4e1a\u754c\u670b\u53cb\u804a\uff0c\u5927\u5bb6\u6240\u5173\u6ce8\u7684\u4e00\u4e2a\u6700\u91cd\u8981\u7684\u8bdd\u9898\uff0c\u4e5f\u662f\u4f1a\u573a\u4e2d\u6700\u7206\u6ee1\u7684talks\u4e4b\u4e00\uff0c\u5c31\u662f\u764c\u75c7\u65e9\u7b5b\u3002\u76ee\u524d\u5927\u5bb6\u6240\u5173\u6ce8\u7684\u4e0d\u4ec5\u662f\u5982\u4f55\u53bb\u8bc6\u522b\u764c\u75c7\u7684\u65e9\u671f\u4fe1\u53f7\uff0c\u540c\u65f6\u5728\u5982\u4f55\u5224\u65ad\u80cc\u666f\u548c\u566a\u97f3\u65b9\u9762\u4e5f\u505a\u4e86\u5f88\u591a\u5de5\u4f5c\u3002\u540c\u65f6\u5728ctDNA\u3001CTC\u548c\u5916\u6ccc\u4f53\u4e0d\u540c\u7ef4\u5ea6\uff0c\u8840\u6d46\u3001\u5c3f\u6db2\u548c\u553e\u6db2\u4e0d\u540c\u6837\u672c\u5c42\u9762\u505a\u4e86\u5168\u9762\u7684\u63a2\u7d22\u3002<\/div>\n
\u00a0<\/div>\n
\u5b66\u672f\u754c\u548c\u5de5\u4e1a\u754c\u4eca\u5e74\u867d\u7136\u6ca1\u6709\u65b0\u7684\u91cd\u5927\u7684\u8fdb\u5c55\uff0c\u3002\u4f46\u662f\u53ef\u4ee5\u770b\u5230\u4e86\u5728\u66f4\u8be6\u7ec6\u7684\u6570\u636e\u3002Grail\uff0c Guardant Health\u548cFreenome\u662f\u5927\u5bb6\u6bd4\u8f83\u5173\u6ce8\u7684\u4e09\u4e2a\u764c\u75c7\u65e9\u7b5b\u516c\u53f8\uff0c\u5176\u4e2dGrail\u5728\u8fd9\u4e2a\u9886\u57df\u91cc\u9762\u6240\u505a\u7684\u5de5\u4f5c\u53ef\u4ee5\u8bf4\u6700\u4e3a\u5e7f\u6cdb\u548c\u6700\u6709\u6df1\u5ea6\u3002Grail\u5c55\u793a\u7684\u662fctDNA fragment size \u7684\u7814\u7a76\uff0cGuardant Health\u5c55\u793a\u4e86\u5927\u80a0\u764c\u65e9\u7b5b\u7684\u6570\u636e\uff0cFreenome\u5c55\u793a\u4e86\u4ed6\u4eec\u72ec\u7279\u7684cfDNA fragment position\u6280\u672f\u3002<\/div>\n
\u65e0\u8bba\u662f\u5b66\u672f\u754c\u548c\u5de5\u4e1a\u754c\u7684\u52aa\u529b\uff0c\u764c\u75c7\u65e9\u7b5b\u8981\u770b\u5230\u5728\u771f\u5b9e\u4e16\u754c\u91cc\u5927\u89c4\u6a21\u7684\u9a8c\u8bc1\u7ed3\u679c\uff0c\u53ef\u80fd\u8fd8\u8981\u518d\u7b49\u4e0a\u4e00\u5e74\u3002<\/div>\n\n
\n
\"640?wx_fmt=jpeg\"\/<\/figure><\/div>\n\n
\u56fe\uff0c\u90ed\u519b\u6559\u6388\u3002\u6765\u81eaAACR\u5b98\u7f51<\/div>\n
\u4ece\u8fd9\u6b21\u5e74\u4f1a\u4e0a\u6765\u770b\uff0c\u6765\u81ea\u4e8e\u4e2d\u56fd\u7684\u58f0\u97f3\u8fd8\u662f\u5f88\u4e0d\u591a\uff0c\u4e0d\u7ba1\u662f\u5de5\u4e1a\u754c\u8fd8\u662f\u5b66\u672f\u754c\uff0c\u7edd\u5927\u591a\u6570\u7684\u7ed3\u679c\u4ecd\u7136\u662f\u4ee5\u6d77\u62a5\u65b9\u5f0f\u5728\u5c55\u793a\uff0c\u53e3\u5934\u62a5\u544a\u5f88\u5c11\uff08\u7f16\u8005\u6ce8\uff1a\u6765\u81ea\u5317\u4eac\u5927\u5b66\u80bf\u7624\u533b\u9662\u7684\u90ed\u519b\u6559\u6388\uff0c\u4f5c\u4e3a\u552f\u4e00\u4e00\u4f4d\u4e9a\u6d32\u5b66\u8005\uff0c\u88ab\u9080\u8bf7\u505a\u5927\u4f1a\u4e3b\u9898\u53d1\u8a00\uff0c\u9898\u4e3a\u201cThe landscape of mucosal melanoma\uff1aa long way to go\u201d\uff09\uff0c\u8fd9\u662f\u6211\u4eec\u4e00\u8d77\u8981\u6765\u52aa\u529b\u7684\u5730\u65b9\u3002<\/div>\n
\u00a0<\/div>\n
\u9644\uff1a\u90e8\u5206\u5728AACR\u5c55\u793a\u7684\u4e2d\u56fd\u764c\u75c7\u7814\u7a76\u6210\u679c<\/div>\n\n
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