\n![\"RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg.gif\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u767e\u5bb6\u8c08<\/div>\n
\u751f\u547d\u5065\u5eb7\u7684\u5148\u950b\u58f0\u97f3<\/div>\n
\u5173\u952e\u8bcd\/NIPT \u53cc\u80ce<\/div>\n
\u00a0<\/div>\n
\u53cc\u80ce\u598a\u5a20\u7387\u9010\u5e74\u5347\u9ad8\uff0c\u540c\u65f6\u76f8\u5bf9\u5355\u80ce\u66f4\u5e38\u89c1\u80ce\u513f\u5f02\u5e38\u3002\u9002\u7528\u4e8e\u5355\u80ce\u7684NIPT\u662f\u5426\u9002\u5408\u53cc\u80ce\u598a\u5a20\u7b5b\u67e5\uff1f2019\u5e746\u67084\u65e5\uff0c\u82f1\u56fd\u80ce\u513f\u533b\u5b66\u57fa\u91d1\u4f1a\uff08FMF\uff09\u8d44\u52a9\u7684\u4e00\u9879\u7814\u7a76\u5728\u5987\u4ea7\u79d1\u6743\u5a01\u533b\u5b66\u671f\u520aUltrasound Obstet Gynecol\u4e0a\u53d1\u8868\uff0c\u4e3aNIPT\u5e94\u7528\u53cc\u80ce\u7b5b\u67e5\u63d0\u4f9b\u4e86\u8bc1\u636e\u3002\u57fa\u56e0\u6167\u9080\u8bf78\u4f4d\u4e34\u5e8a\u548c\u4ea7\u4e1a\u76f8\u5173\u7684\u4ea7\u524d\u4e13\u5bb6\u89e3\u8bfb\u5982\u4e0b\uff08\u5728\u516c\u4f17\u53f7\u4e3b\u9875\u56de\u590d\u201c\u53cc\u80ce\u201d\u53ef\u83b7\u5f97\u6587\u732ePDF\uff09\u3002<\/div>\n
\u82e5\u60a8\u613f\u610f\u89e3\u8bfb\u6587\u732e\uff0c\u6b22\u8fce\u6295\u7a3f\u81f3 info@genonet.cn<\/div>\n
\u00a0<\/div>\n
\u5212\u91cd\u70b9<\/div>\n
1. \u9488\u5bf910+0\u81f314+1\u5468\u5b55\u9f84\u53cc\u80de\u80ce\u5b55\u5987\uff0c997\u4f4d\u5b55\u5987\u7684cfDNA\u6837\u672c \u3002<\/div>\n
2. NIPT\u68c0\u6d4b\u80ce\u513f21-\u4e09\u4f53\u7684\u8868\u73b0\u4e0e\u5df2\u62a5\u9053\u7684\u5355\u80ce\u5b55\u5987\u68c0\u6d4b\u7ed3\u679c\u63a5\u8fd1\uff0c\u4f18\u4e8e\u65e9\u5b55\u671f\u8054\u5408\u7b5b\u67e5\u4e0e\u4e2d\u5b55\u671f\u8054\u5408\u7b5b\u67e5\u3002\u7531\u4e8e18 -\u4e09\u4f53\u300113-\u4e09\u4f53\u75c5\u4f8b\u6570\u8f83\u5c11\uff0c\u5c1a\u4e0d\u80fd\u7cbe\u786e\u8bc4\u4f30\u3002<\/div>\n
3. \u201cNIPT\u53ef\u4f5c\u4e3a\u53cc\u80ce\u65e9\u671f\u67d3\u8272\u4f53\u975e\u6574\u500d\u4f53\u5f02\u5e38\u7684\u4e00\u7ebf\u7b5b\u67e5\u6280\u672f\u201d\u3002<\/div>\n
\u00a0<\/div>\n
1<\/div>\n
\u6587\u732e\u7b80\u4ecb<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXm47phnoNzlJJkdFic1wqQzzGOSkUSNB6vM6TBoRycy2EyORdoleMQG1w\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXm47phnoNzlJJkdFic1wqQzzGOSkUSNB6vM6TBoRycy2EyORdoleMQG1w.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe1\uff1a\u6587\u732e\u53d1\u8868\u9875\u9762\uff0c\u6765\u6e90\uff1aUltrasound Obstet Gynecol<\/div>\n
\u00a0<\/div>\n
\uff08\u6b64\u90e8\u5206\u7ecf\u6388\u6743\u6458\u5f55\u81ea\u738b\u5a01\u535a\u58eb\u7684\u535a\u5ba2 http:\/\/blog.sina.com.cn\/s\/blog_bcb043950102zh1m.html\uff0c\u5728\u6b64\u611f\u8c22\uff09<\/div>\n
\u00a0 \u76ee\u00a0 \u6807\u00a0\u00a0\u00a0\u00a0<\/div>\n
\u901a\u8fc7\u5355\u4e2d\u5fc3\u524d\u77bb\u6027\u7814\u7a76\u6570\u636e\uff0c\u7ed3\u5408\u591a\u4e2d\u5fc3\u7684\u6587\u732e\u68c0\u7d22\u6570\u636e\u7684\u835f\u8403\u5206\u6790\uff0c\u4ece\u800c\u786e\u8ba4NIPT\u5728\u53cc\u80ce\u598a\u5a20cfDNA\u7b5b\u67e5\u4e2d\u4e0e\u5355\u80ce\u7b5b\u67e5\u7ed3\u679c\u7684\u4e00\u81f4\u6027\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0 \u65b9\u00a0 \u6cd5\u00a0\u00a0\u00a0\u00a0\u00a0<\/div>\n
\u524d\u77bb\u6027\u7814\u7a76\u572810+0\u81f314+1\u5468\u5b55\u9f84\u53cc\u80de\u80ce\u5b55\u5987\u4e2d\u5c55\u5f00\uff0c\u53d7\u68c0\u5b55\u5987\u6765\u81ea\u4e24\u4e2a\u5b55\u5987\u7fa4\u4f53\uff0c\u4e00\u90e8\u5206\u662f\u4e24\u5bb6\u8bca\u6240\/\u533b\u9662\u7684\u81ea\u8350\u5b55\u5987\uff1b\u53e6\u4e00\u90e8\u5206\u6765\u81ea\u82f1\u56fd\u56fd\u5bb6\u533b\u7597\u670d\u52a1\u4f53\u7cfb\uff08NHS\uff09\u5185\u7684\u4e00\u5bb6\u533b\u9662\uff0c\u5b55\u5987\u5728\u5e38\u89c4\u65e9\u5b55\u671f\u8054\u5408\u7b5b\u67e5\u540e\u9009\u62e9\u8fdb\u884cNIPT\u68c0\u6d4b\u3002<\/div>\n
\u6587\u732e\u68c0\u7d22\u6570\u636e\uff0c\u662f\u901a\u8fc7MEDLINE\u3001EMBASE\u3001CENTRAL\u3001ClinicalTrials.gov\u53ca\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u56fd\u9645\u4e34\u5e8a\u8bd5\u9a8c\u6ce8\u518c\u5e73\u53f0\uff08ICTRP)\u7b49\u5e73\u53f0\uff0c\u521d\u9009\u51fa329\u7bc7\u6587\u732e\uff0c\u5e76\u7b5b\u9009\u51fa\u6709\u4e34\u5e8a\u9a8c\u8bc1\u4e14\u7ecf\u8fc7\u540c\u884c\u8bc4\u8bae\u7684\u53cc\u80ce\u598a\u5a20\u76f8\u5173\u7814\u7a76\u76847\u7bc7\u8bba\u6587\uff0c\u8fde\u540c\u524d\u77bb\u6027\u7814\u7a76\u6570\u636e\u51718\u9879\u7814\u7a76\u7ed3\u679c\u4e00\u8d77\u8fdb\u884c\u835f\u8403\u5206\u6790\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0 \u7ed3\u00a0 \u679c\u00a0 \u00a0\u00a0\u00a0 \u00a0<\/div>\n
1. \u7814\u7a76\u7b2c\u4e00\u90e8\u5206\uff1a\u524d\u77bb\u6027\u7814\u7a76\u7ed3\u679c<\/div>\n
\u5728997\u540d\u53cc\u80ce\u598a\u5a20\u5b55\u5987\u4e2d\uff0c NIPT\u7b5b\u67e5\u80ce\u513f21-\u4e09\u4f53\u300118-\u4e09\u4f53\u53ca13-\u4e09\u4f53\u7684\u4e34\u5e8a\u8868\u73b0\u3002<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmDKnnxs2cc2scwPQgbADjN9cb05kFGpcZv4rZO7coqYgsjdAVvkEgIA\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmDKnnxs2cc2scwPQgbADjN9cb05kFGpcZv4rZO7coqYgsjdAVvkEgIA.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe2\uff1a\u524d\u77bb\u6027\u7814\u7a76\u7ed3\u679c\uff0c\u6765\u6e90\uff1aUltrasound Obstet Gynecol\uff0c\u7ffb\u8bd1\uff1a\u738b\u5a01\u535a\u58eb<\/div>\n
2.\u00a0\u7814\u7a76\u7b2c\u4e8c\u90e8\u5206\uff1a \u835f\u8403\u5206\u6790\uff087\u7bc7\u8bba\u6587+\u7b2c\u4e00\u90e8\u5206\u7814\u7a76\u6570\u636e\uff09<\/div>\n
\u5171\u67097\u7bc7\u8bba\u6587\u7eb3\u5165\u835f\u8403\u5206\u6790\uff0c\u5176\u4e2d6\u7bc7\u6765\u81ea\u6211\u56fd\u5b66\u8005\uff0c\u5206\u522b\u662f\u534e\u5927\u533b\u5b66\u4e0e\u524d\u9999\u6e2f\u4e2d\u6587\u5927\u5b66\u7684\u5218\u5b50\u5065\u6559\u6388\u56e2\u961f(2013)\u3001\u4e2d\u5c71\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662\u7684\u65b9\u7fa4\u6559\u6388\u56e2\u961f(2014)\u3001\u4e2d\u4fe1\u6e58\u96c5\u751f\u6b96\u4e0e\u9057\u4f20\u4e13\u79d1\u533b\u9662\u7684\u5362\u5149\u7407\u6559\u6388\u56e2\u961f(2016)\u5408\u4f5c\u7684\u4e09\u9879\u7814\u7a76\uff1b\u6b64\u5916\u8fd8\u6709\u6b66\u6c49\u4e2d\u5357\u533b\u9662\u7684\u5f20\u5143\u73cd\u6559\u6388\u56e2\u961f(2017)\u3001\u5e7f\u4e1c\u7701\u5987\u5e7c\u4fdd\u5065\u9662\u7684\u5c39\u7231\u534e\u6559\u6388\u56e2\u961f(2018)\uff0c\u76db\u4eac\u533b\u9662\u7684\u5218\u5f69\u971e\u6559\u6388\u56e2\u961f(2019)\u7684\u7814\u7a76\u8bba\u6587\u3002\u53e6\u5916\u4e00\u9879\u7814\u7a76\u6765\u81ea\u6cd5\u56fd\u4e0e\u6bd4\u5229\u65f6\u5b66\u8005(2018)\uff08\u89c1\u4e0b\u56fe\uff09\u3002<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmdb1DYh0g0GZrnKojzlLPJM6RPPHCWO5hzX1X3OAWqmfEG2FzoPoib5A\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmdb1DYh0g0GZrnKojzlLPJM6RPPHCWO5hzX1X3OAWqmfEG2FzoPoib5A.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe3\uff1a\u6587\u7ae0\u5f15\u7528\u76847\u7bc7\u6587\u732e\u6570\u636e\u7684\u603b\u7ed3\uff0c\u6765\u6e90\uff1aUltrasound Obstet Gynecol<\/div>\n
\u5728\u53cc\u80ce\u598a\u5a20\u5b55\u5987\u4e2d\uff0cNIPT\u7b5b\u67e5\u80ce\u513f21-\u4e09\u4f53\u300118-\u4e09\u4f53\u53ca13-\u4e09\u4f53\u7684\u4e34\u5e8a\u8868\u73b0\uff1a<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmsUDLymTiasYwUPmghUicQdNj6V2bDkI4H9GXOmMBfQFRjGOIK0m9x77A\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmsUDLymTiasYwUPmghUicQdNj6V2bDkI4H9GXOmMBfQFRjGOIK0m9x77A.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe4\uff1a\u835f\u8403\u5206\u6790\u7ed3\u679c\uff0c\u6765\u6e90\uff1aUltrasound Obstet Gynecol<\/div>\n
\u6587\u7ae0\u8fd8\u5bf9\u6bd4\u4e86\u5728\u5355\u80ce\u598a\u5a20\u5b55\u5987\u4e2d\uff0cNIPT\u7b5b\u67e5\u80ce\u513f21-\u4e09\u4f53\u300118-\u4e09\u4f53\u53ca13-\u4e09\u4f53\u7684\u4e34\u5e8a\u8868\u73b0\uff0c\u6570\u636e\u6765\u81ea\u8be5\u56e2\u961f2017\u5e74\u8bba\u6587[3]\uff1a<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmEadTBAuMcGm8cb6oYLaRzlKL3Q7b9P8SHVJ02NwN0u2Kaw8iaxapRxg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmEadTBAuMcGm8cb6oYLaRzlKL3Q7b9P8SHVJ02NwN0u2Kaw8iaxapRxg.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe5\uff1a\u5355\u80ce\u5206\u6790\u6570\u636e\u5bf9\u6bd4\uff0c\u6765\u6e90\uff1aUltrasound Obstet Gynecol<\/div>\n
\u00a0\u7ed3\u00a0 \u8bba\u00a0 \u00a0\u00a0 \u00a0<\/div>\n
\u901a\u8fc7\u835f\u8403\u5206\u6790\u53ef\u4ee5\u770b\u5230\uff0c\u5728\u53cc\u80ce\u598a\u5a20\u4e2d\uff0cNIPT\u68c0\u6d4b\u80ce\u513f21-\u4e09\u4f53\u7684\u8868\u73b0\u4e0e\u5df2\u62a5\u9053\u7684\u5355\u80ce\u5b55\u5987\u7ed3\u679c\u63a5\u8fd1\uff0c\u4f18\u4e8e\u65e9\u5b55\u671f\u8054\u5408\u7b5b\u67e5\u4e0e\u4e2d\u5b55\u671f\u8054\u5408\u7b5b\u67e5\u3002\u7531\u4e8e18 -\u4e09\u4f53\u300113-\u4e09\u4f53\u75c5\u4f8b\u6570\u8f83\u5c11\uff0c\u5c1a\u4e0d\u80fd\u7cbe\u786e\u7ed9\u51fa\u8bc4\u4f30\u7ed3\u679c\u3002<\/div>\n
\u00a0<\/div>\n
2<\/div>\n
\u4e13\u5bb6\u89e3\u8bfb<\/div>\n
\u57fa\u56e0\u6167\u7279\u90808\u4f4d\u77e5\u540d\u4e34\u5e8a\u548c\u4ea7\u4e1a\u4e13\u5bb6\u5bf9\u6587\u7ae0\u8fdb\u884c\u89e3\u8bfb\uff1a(\u4ee5\u4e0b\u6392\u5e8f\u4e0d\u5206\u5148\u540e)<\/div>\n
\u5c39\u7231\u534e\uff08\u5e7f\u4e1c\u7701\u5987\u5e7c\u4fdd\u5065\u9662\u533b\u5b66\u9057\u4f20\u4e2d\u5fc3\u4e3b\u4efb\uff09<\/div>\n
\u59da\u5b8f\uff08\u9646\u519b\u519b\u533b\u5927\u5b66\u897f\u5357\u533b\u9662\u4ea7\u524d\u8bca\u65ad\u4e2d\u5fc3\u4e3b\u4efb\uff09<\/div>\n
\u848b\u5b87\u6797\uff08\u5317\u4eac\u534f\u548c\u533b\u9662\u4ea7\u79d1\u4e3b\u4efb\u52a9\u7406\uff09<\/div>\n
\u5ed6\u4e16\u79c0\uff08\u6cb3\u5357\u7701\u4eba\u6c11\u533b\u9662\u533b\u5b66\u9057\u4f20\u4e2d\u5fc3\u4e3b\u4efb\uff09<\/div>\n
\u738b\u5a01\uff08\u534e\u5927\u667a\u9020\u526f\u603b\u88c1\uff09<\/div>\n
\u4f0d\u542f\u71b9\uff08\u4f18\u8fc5\u533b\u5b66CTO\uff09<\/div>\n
David Cram\u00a0\uff08\u8d1d\u745e\u57fa\u56e0\u9996\u5e2d\u9057\u4f20\u79d1\u5b66\u5bb6\uff09<\/div>\n
\u7530\u57c2\uff08\u5143\u7801\u57fa\u56e0\u521b\u59cb\u4eba\uff09<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmjalyEib4KbceV7wv0l4wtUHaInbpl8sWHXnMRqwAyWCiaU5iaicoOLz0PQ\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmjalyEib4KbceV7wv0l4wtUHaInbpl8sWHXnMRqwAyWCiaU5iaicoOLz0PQ.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u5c39\u7231\u534e<\/div>\n
\u5e7f\u4e1c\u7701\u5987\u5e7c\u4fdd\u5065\u9662\u533b\u5b66\u9057\u4f20\u4e2d\u5fc3\u4e3b\u4efb<\/div>\n
1. NIPT\u5728\u53cc\u80ce\u598a\u5a20\u5b55\u5987\u4e2d\u7684\u6027\u80fd\u660e\u663e\u4f18\u4e8e\u76ee\u524d\u7ed3\u5408\u8d85\u58f0\u7684\u751f\u5316\u8840\u6e05\u5b66\u7b5b\u67e5\u65b9\u6cd5\uff0c\u53ef\u4f5c\u4e3a\u53cc\u80ce\u65e9\u671f\u67d3\u8272\u4f53\u975e\u6574\u500d\u4f53\u5f02\u5e38\u7684\u4e00\u7ebf\u7b5b\u67e5\u6280\u672f\u3002<\/div>\n
2. \u6700\u597d\u8fd8\u662f\u6309\u7167\u5355\u7ed2\u6bdb\u819c\u53cc\u80ce\u4e0e\u53cc\u7ed2\u6bdb\u819c\u53cc\u80ce\u5206\u522b\u8bc4\u4f30\u68c0\u6d4b\u6027\u80fd\u3002<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmn7Uqoek92gjicLucFgFhYSATQhaweBfNAyB6ZiccdIn2Slia7aonzsEtQ\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmn7Uqoek92gjicLucFgFhYSATQhaweBfNAyB6ZiccdIn2Slia7aonzsEtQ.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u59da\u5b8f<\/div>\n
\u9646\u519b\u519b\u533b\u5927\u5b66\u897f\u5357\u533b\u9662\u4ea7\u524d\u8bca\u65ad\u4e2d\u5fc3\u4e3b\u4efb<\/div>\n
1. \u6587\u7ae0\u9488\u5bf9NIPT\u5bf9\u53cc\u80ce\u548c\u5355\u80ce\u7684\u4e34\u5e8a\u8fd0\u7528\u6027\u80fd\u8fdb\u884c\u6bd4\u8f83\uff0c\u53cc\u80ce\u6570\u636e\u7531\u524d\u77bb\u6027\u7814\u7a76\u6570\u636e\u548c\u6587\u732e\u68c0\u7d22\u6570\u636e\u7ec4\u6210\uff0c\u524d\u8005\u6570\u636e\u76f8\u5bf9\u8f83\u5c11\u3002\u524d\u77bb\u6027\u7814\u7a76\u6570\u636e\u4e2d\u67091\u4f8b\u771f\u9633\u6027\u6f0f\u68c0\uff0c\u8fd9\u91cc\u518d\u6b21\u5f3a\u8c03\u4e86NIPT\u662f\u4e00\u9879\u7b5b\u67e5\u6280\u672f\uff0c\u6280\u672f\u7684\u5c40\u9650\u6027\u4f1a\u5bfc\u81f4\u5047\u9633\u6027\u548c\u5047\u9634\u6027\u3002<\/div>\n
2. \u6587\u7ae0\u5f97\u51fa\u7684\u7ed3\u8bba\u662fNIPT\u5bf9\u4e8e 21\u4e09\u4f53\u7684\u68c0\u6d4b\u6027\u80fd\u53cc\u80ce\u4e0e\u5355\u80ce\u76f8\u4f3c\u3002\u4f18\u4e8e\u65e9\u5b55\u671f\u8054\u5408\u7b5b\u67e5\u6548\u7387\u53ca\u4e2d\u5b55\u671f\u8840\u6e05\u5b66\u7b5b\u67e5\uff0c18\u4e09\u4f53\u548c13\u4e09\u4f53\u75c5\u4f8b\u6570\u91cf\u592a\u5c11\uff0c\u65e0\u6cd5\u51c6\u786e\u8bc4\u4f30NIPT\u68c0\u6d4b\u7684\u9884\u6d4b\u6027\u80fd\u3002\u00a0<\/div>\n
3. \u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u6587\u7ae0\u4e2d\u68c0\u6d4b\u5931\u8d25\u7387\u8f83\u9ad8\uff0811.1%\uff09\uff0c\u4ece\u5165\u7ec4\u6837\u672c\u57fa\u672c\u7279\u5f81\u6765\u770b\uff0c\u4e00\u65b9\u9762\u53ef\u80fd\u4e0e\u5e73\u5747\u5b55\u5468\u5c0f\u6709\u5173\uff0812.1\u5468\uff0c10.7-12.9\uff09\uff0c\u53e6\u4e00\u65b9\u9762\uff0c\u4e0e\u5b55\u5987\u4f53\u91cd\u504f\u91cd\u76f8\u5173\uff0869.0kg\uff0c60.4-82.6\uff09\u3002\u00a0<\/div>\n
4. \u5efa\u8bae\uff1a\u5728\u65e9\u5b55\u671f\u786e\u5b9a\u53cc\u80ce\u7684\u5b55\u5468\u3001\u7ed2\u6bdb\u819c\u6027\u5e76\u8fdb\u884cNT\u6d4b\u91cf\uff0c\u8981\u4e25\u683c\u9075\u5faa\u56fd\u536b\u529e\u5987\u5e7c\u53f8\u30102016\u301145\u53f7\u6587\u4ef6\u5bf9\u4e8eNIPT\u7684\u89c4\u5b9a\uff0c\u628a\u63e1\u5b55\u5468\u5927\u5c0f\uff0c\u5b55\u5987\u4f53\u91cd\uff0c\u5e74\u9f84\uff0cIVF\u53d7\u5b55\u7b49\u9002\u5e94\u75c7\u7684\u638c\u63e1\u3002\u53cc\u80ce\u76ee\u524d\u5c1a\u65e0\u6700\u4f73\u7684\u975e\u6574\u500d\u4f53\u7b5b\u67e5\u65b9\u6848\uff0cNIPT\u65e0\u7591\u662f\u73b0\u9636\u6bb5\u5e38\u89c4\u598a\u5a20\u4eba\u7fa4\u53cc\u80ce\u67d3\u8272\u4f53\u975e\u6574\u500d\u4f53\u7b5b\u67e5\u7684\u6700\u4f73\u65b9\u6cd5\uff0c\u4f46NIPT\u7528\u4e8e\u53cc\u80ce\u7b5b\u67e5\u4ecd\u9700\u66f4\u591a\u7814\u7a76\u6570\u636e\uff0c\u4ee5\u63d0\u9ad8\u7b5b\u67e5\u7684\u51c6\u786e\u6027\u3002<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmiazCicQTtwp3Yk8zDlaIG3pTCFZGXVq5MNXWUHtTrWNgeJic472HJ2mwg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmiazCicQTtwp3Yk8zDlaIG3pTCFZGXVq5MNXWUHtTrWNgeJic472HJ2mwg.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u848b\u5b87\u6797<\/div>\n
\u5317\u4eac\u534f\u548c\u533b\u9662\u4ea7\u79d1\u4e3b\u4efb\u52a9\u7406<\/div>\n
1. \u53cc\u80ce\u598a\u5a20\u7ea6\u5360\u603b\u4f53\u598a\u5a20\u76842-3%\uff0c\u7531\u4e8e\u5b58\u5728\u5305\u62ec\u7ed3\u6784\u5f02\u5e38\u5728\u5185\u7684\u8bb8\u591a\u5408\u5e76\u75c7\u548c\u5e76\u53d1\u75c7\uff0c\u6240\u4ee5\u5c5e\u4e8e\u9ad8\u5371\u598a\u5a20\u7684\u8303\u7574\u3002\u9488\u5bf9\u5355\u80ce\u598a\u5a20\u7684\u4ea7\u524d\u7b5b\u67e5\u7b56\u7565\u5e94\u7528\u4e8e\u53cc\u80ce\u598a\u5a20\u5747\u6709\u68c0\u51fa\u6548\u7387\u4e0b\u964d\u7684\u95ee\u9898\uff0c\u8fd9\u5f80\u5f80\u4e0e\u53cc\u5375\u53cc\u80ce\u7684\u9057\u4f20\u5f02\u8d28\u6027\uff0cIVF-ET\u598a\u5a20\u6bd4\u4f8b\u8f83\u9ad8\uff0c\u6bcd\u4f53\u8840\u6db2\u7a00\u91ca\u6027\u7a0b\u5ea6\u8f83\u9ad8\u7b49\u7b49\u6709\u5173\u3002\u540c\u65f6\u4ecb\u5165\u6027\u4ea7\u524d\u8bca\u65ad\u7684\u64cd\u4f5c\u590d\u6742\u6027\uff0c\u7a7f\u523a\u548c\u8bca\u65ad\u8d39\u7528\u4ee5\u53ca\u6d41\u4ea7\u51e0\u7387\u4e5f\u8f83\u5355\u80ce\u4e3a\u9ad8\u3002<\/div>\n
2. \u56fd\u9645\u4e0a\u53cc\u80ce\u7279\u522b\u662f\u53cc\u7ed2\u53cc\u7f8a\u598a\u5a20\u7684\u4ea7\u524d\u7b5b\u67e5\u4e3b\u8981\u9009\u62e9\u65e9\u5b55\u671fNT\u7b5b\u67e5\u6216\u65e9\u5b55\u671fNT\u53ca\u8840\u6e05\u5b66\u8054\u5408\u7684\u7b5b\u67e5\uff0c\u800c\u4e2d\u5b55\u671f\u8840\u6e05\u5b66\u7b5b\u67e5\u7531\u4e8e\u68c0\u51fa\u7387\u8fc7\u4f4e\u548c\u5047\u9633\u6027\u7387\u8fc7\u9ad8\u5df2\u7ecf\u4e0d\u4f5c\u4e3a\u53cc\u80ce\u7b5b\u67e5\u7684\u63a8\u8350\u7b56\u7565\u3002\u00a0<\/div>\n
3. \u6211\u56fd\u65e9\u5b55\u671f\u8054\u5408\u7b5b\u67e5\u4e00\u76f4\u6ca1\u6709\u5f97\u5230\u5f88\u597d\u7684\u5f00\u5c55\uff0c\u969c\u788d\u56e0\u7d20\u5305\u62ec\u5b55\u5987\u6765\u9662\u5b55\u5468\u8fc7\u5927\u800c\u9519\u5931\u7b5b\u67e5\u65f6\u673a\uff0c\u8d85\u58f0NT\u68c0\u6d4b\u7684\u89c4\u8303\u5f00\u5c55\u4ecd\u6709\u969c\u788d\uff0c\u9ad8\u5371\u4eba\u7fa4\u540e\u7eed\u7684\u7ed2\u6bdb\u7a7f\u523a\u8bca\u65ad\u65e0\u6cd5\u5f00\u5c55\u7b49\u7b49\u3002\u6240\u4ee5\u6211\u56fd\u5927\u591a\u6570\u7684\u53cc\u80ce\u598a\u5a20\u4ecd\u7136\u505c\u7559\u5728\u4e2d\u5b55\u671f\u8840\u6e05\u5b66\u7b5b\u67e5\u7684\u4f4e\u7ea7\u9636\u6bb5\u3002\u00a0<\/div>\n
4. \u76ee\u524d\u8f83\u4e3a\u5e7f\u6cdb\u7684\u4e13\u5bb6\u5171\u8bc6\u5305\u62ec\u53cc\u80ce\u598a\u5a20\u7684NIPT\u5931\u8d25\u7387\u8f83\u5355\u80ce\u598a\u5a20\u504f\u9ad8\uff0c\u68c0\u51fa\u7387\u6709\u4e00\u5b9a\u7a0b\u5ea6\u7684\u4e0b\u964d\uff0c\u6240\u4ee5\u57282016\u5e74\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u9881\u5e03\u5b9e\u65bd\u7684\u5168\u56fdNIPT\u6280\u672f\u89c4\u8303\u4e2d\u5c06NIPT\u7684\u53cc\u80ce\u598a\u5a20\u5e94\u7528\u5217\u4e3a\u201c\u614e\u7528\u201d\u7ea7\u522b\uff0c\u4f46NIPT\u7684\u7b5b\u67e5\u68c0\u51fa\u6548\u679c\u662f\u5426\u4ecd\u7136\u4f18\u4e8e\u65e9\u5b55\u671f\u8054\u5408\u7b5b\u67e5\uff0c\u53ef\u4ee5\u6210\u4e3a\u4e00\u7ebf\u63a8\u8350\u7684\u65b9\u6848\uff0c\u76ee\u524d\u4ecd\u7136\u9700\u8981\u66f4\u52a0\u786e\u51ff\u7684\u8bc1\u636e\u3002\u00a0<\/div>\n
5. \u82f1\u56fd\u80ce\u513f\u533b\u5b66\u57fa\u91d1\u4f1aK. H. NICOLAIDES\u6559\u6388\u4e3b\u6301\u7684\u8fd9\u4e00\u5355\u4e2d\u5fc3\u7814\u7a76\u7ed3\u5408\u591a\u4e2d\u5fc3\u835f\u8403\u5206\u6790\u7814\u7a76\u7ed9\u8fd9\u4e00\u95ee\u9898\u63d0\u4f9b\u4e86\u8f83\u4e3a\u6e05\u6670\u7684\u8bc1\u636e\u3002\u6587\u4e2d\u63d0\u5230\u53cc\u80ce\u598a\u5a20\u7684\u5931\u8d25\u7387\u662f\u5355\u80ce\u598a\u5a20\u7684\u4e09\u500d\u3002\u8be5\u7814\u7a76\u5f97\u51fa\u7684\u7ed3\u8bba\uff0cNIPT\u7528\u4e8e\u53cc\u80ce\u598a\u5a20\u768421\u4e09\u4f53\u300118\u4e09\u4f53\u7684\u7b5b\u67e5\uff0c\u603b\u4f53\u7b5b\u67e5\u6548\u7387\u8f83\u5355\u80ceNIPT\u7b5b\u67e5\u4e3a\u4f4e\uff0c\u4f46\u4f18\u4e8e\u65e9\u5b55\u671f\u8054\u5408\u7b5b\u67e5\uff08\u7279\u522b\u662f\u5047\u9633\u6027\u7387\u4e0e\u4e4b\u76f8\u6bd4\u975e\u5e38\u4f4e\uff09\u3002<\/div>\n
6. \u603b\u4f53\u800c\u8a00\uff0cNIPT\u68c0\u6d4b\u5e94\u8be5\u53ef\u4ee5\u63d0\u4f9b\u7ed9\u53cc\u80ce\u598a\u5a20\u5305\u62ec\u53cc\u7ed2\u53cc\u7f8a\u598a\u5a20\u4f5c\u4e3a\u4e00\u7ebf\u7b5b\u67e5\u7684\u65b9\u6cd5\uff0c\u4f46\u8f83\u5355\u80ce\u800c\u8a00\u7b5b\u67e5\u6548\u7387\u4ecd\u4f1a\u6709\u4e00\u5b9a\u7684\u4e0b\u964d\uff0c\u5931\u8d25\u7387\u4f1a\u6709\u4e00\u5b9a\u7684\u63d0\u5347\uff0c\u8fd9\u662f\u9700\u8981\u5728\u68c0\u6d4b\u524d\u548c\u5b55\u5987\u505a\u597d\u54a8\u8be2\u7684\u5730\u65b9\u3002\u6211\u56fd\u5bf9\u4e8e\u65e9\u5b55\u671f\u7b5b\u67e5\u5f00\u5c55\u8fd8\u4e0d\u5c3d\u5982\u4eba\u610f\u7684\u5730\u65b9\uff0cNIPT\u7b5b\u67e5\u65b9\u6cd5\u7684\u63d0\u4f9b\u548c\u63a8\u5e7f\uff0c\u6709\u52a9\u4e8e\u63d0\u5347\u53cc\u80ce\u598a\u5a20\u4ea7\u524d\u7b5b\u67e5\u4e34\u5e8a\u670d\u52a1\u7684\u8d28\u91cf\u3002<\/div>\n\n
\n![\"RmFicvQBAkgDR12qkM6KxTpbm3DjZlsacibD67RFz9xWDp8OUXJMz48KHxt0WriaQEJHsfsr9qdhEkCYgR9s0aGNA\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDR12qkM6KxTpbm3DjZlsacibD67RFz9xWDp8OUXJMz48KHxt0WriaQEJHsfsr9qdhEkCYgR9s0aGNA.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u5ed6\u4e16\u79c0<\/div>\n
\u6cb3\u5357\u7701\u4eba\u6c11\u533b\u9662\u533b\u5b66\u9057\u4f20\u4e2d\u5fc3\u4e3b\u4efb<\/div>\n
1. \u80ce\u513f\u67d3\u8272\u4f53\u975e\u6574\u500d\u4f53\u65e0\u521b\u4ea7\u524d\u68c0\u6d4b\u662f\u5229\u7528\u9ad8\u901a\u91cf\u6d4b\u5e8f\u5e73\u53f0\uff0c\u901a\u8fc7\u91c7\u96c6\u5b55\u5987\u5916\u5468\u8840\uff0c\u5bf9\u8840\u6d46\u4e2d\u7684\u6e38\u79bbDNA\u7247\u6bb5\uff08\u5305\u542b\u80ce\u513f\u6e38\u79bbDNA\uff09\u8fdb\u884c\u6d4b\u5e8f\uff0c\u7ed3\u5408\u751f\u7269\u4fe1\u606f\u5206\u6790\uff0c\u8ba1\u7b97\u51fa\u80ce\u513f\u60a3\u67d3\u8272\u4f53\u975e\u500d\u4f53\u7684\u75be\u75c5\u98ce\u9669\u3002\u6b64\u6280\u672f\u80fd\u540c\u65f6\u68c0\u6d4b\u5e38\u89c1\u7684\u67d3\u8272\u4f53\u4e09\u4f53\u7efc\u5408\u5f81\uff1a\u5510\u6c0f\u7efc\u5408\u5f81\uff08T21\uff09\u3001\u7231\u5fb7\u534e\u6c0f\u7efc\u5408\u5f81(T18\uff09\u3001\u5e15\u9676\u6c0f\u7efc\u5408\u5f81\uff08T13\uff09\uff0c\u6709\u6548\u8865\u5145\u4e86\u73b0\u6709\u7684\u4ea7\u524d\u7b5b\u67e5\u3001\u4ea7\u524d\u8bca\u65ad\u4f53\u7cfb\u3002\u4f46\u662f\u8be5\u6280\u672f\u4e5f\u6709\u5176\u9002\u7528\u8303\u56f4\uff0c\u56fd\u536b\u529e\u5987\u5e7c\u53d1[2016]45\u53f7\u300a\u56fd\u5bb6\u536b\u751f\u8ba1\u751f\u59d4\u529e\u516c\u5385\u5173\u4e8e\u89c4\u8303\u6709\u5e8f\u5f00\u5c55\u5b55\u5987\u5916\u5468\u8840\u80ce\u513f\u6e38\u79bbDNA\u4ea7\u524d\u7b5b\u67e5\u4e0e\u8bca\u65ad\u5de5\u4f5c\u7684\u901a\u77e5\u300b\u4e2d\u5c06\u53cc\u80ce\u598a\u5a20\uff0c\u5f52\u7c7b\u4e3a\u614e\u7528\u4eba\u7fa4\uff0c\u8ba4\u4e3a\u68c0\u6d4b\u51c6\u786e\u6027\u6709\u4e00\u5b9a\u7a0b\u5ea6\u4e0b\u964d\uff0c\u68c0\u51fa\u6548\u679c\u4e0d\u660e\u786e\u3002\u00a0<\/div>\n
2. \u8fd9\u7bc7\u7531\u82f1\u56fd\u548c\u897f\u73ed\u7259\u79d1\u5b66\u5bb6\u9886\u8854\u7684\u79d1\u7814\u56e2\u961f\u53d1\u8868\u7684\u6587\u7ae0\u4e3aNIPT\u5728\u53cc\u80ce\u598a\u5a20\u4e2d\u7684\u5e94\u7528\u63d0\u4f9b\u4e86\u652f\u6301\u8bc1\u636e\uff0c\u8ba4\u4e3a\u5229\u7528cfDNA\u68c0\u6d4b21\u4e09\u4f53\u5728\u53cc\u80ce\u548c\u5355\u80ce\u4e2d\u7ed3\u679c\u76f8\u4f3c\uff0c\u8fd9\u4f7fNIPT\u68c0\u6d4b\u8303\u56f4\u8fdb\u4e00\u6b65\u6269\u5927\u3002\u00a0<\/div>\n
3. \u76ee\u524d\u56fd\u536b\u529e\u5987\u5e7c\u53d1[2016]45\u53f7\u6587\u4ee5\u53ca\u6700\u8fd1\u7684\u5b55\u5987\u5916\u5468\u8840\u80ce\u513f\u6e38\u79bbDNA\u4ea7\u524d\u7b5b\u67e5\u5b9e\u9a8c\u5ba4\u6280\u672f\u4e13\u5bb6\u5171\u8bc6\u4e2d\u7684\u89c4\u5b9a\uff1aNIPT\u9633\u6027\u68c0\u51fa\u7387\u7684T21\u4e0d\u4f4e\u4e8e95%\uff0cT18\u4e0d\u4f4e\u4e8e85%\uff0cT13\u4e0d\u4f4e\u4e8e70%\u3002T21\u3001T18\u3001T13\u7684\u590d\u5408\u5047\u9633\u6027\u7387\u4e0d\u9ad8\u4e8e 0.5%\u3002\u53ef\u4ee5\u770b\u51fa\uff0c\u6587\u7ae0\u4e2d\u53cc\u80ce\u6837\u672c\u768421\u4e09\u4f53\u548c18\u4e09\u4f53\u8fd8\u662f\u90fd\u7b26\u5408\u6807\u51c6\u7684\uff0c\u800c13\u4e09\u4f53\u7684\u68c0\u51fa\u738766.7%\u5219\u4f4e\u4e8e\u6807\u51c6\u4e2d\u768470%\u3002\u00a0<\/div>\n
4. \u56e0\u6b64\u53ef\u4ee5\u770b\u51fa\uff0c\u5bf9\u4e8e21\u4e09\u4f53\u800c\u8a00\uff0c\u5b55\u5987\u5916\u5468\u8840\u80ce\u513f\u6e38\u79bbDNA\u4ea7\u524d\u68c0\u6d4b\u5728\u53cc\u80ce\u598a\u5a20\u5b55\u5987\u4e2d\u7684\u6027\u80fd\u4e0e\u5728\u5355\u80ce\u598a\u5a20\u5b55\u5987\u4e2d\u7684\u6027\u80fd\u76f8\u4f3c\uff0c\u53ef\u5728\u4e34\u5e8a\u54a8\u8be2\u4e2d\u9002\u5f53\u7ed9\u4e88\u5efa\u8bae\u3002\u800c18\u4e09\u4f53\u548c13\u4e09\u4f53\u7684\u6837\u672c\u6570\u8f83\u5c11\uff0c\u4e0d\u8db3\u4ee5\u51c6\u786e\u8bc4\u4f30NIPT\u68c0\u6d4b\u7684\u9884\u6d4b\u6027\u80fd\uff0c\u6709\u5f85\u8fdb\u4e00\u6b65\u7814\u7a76\u3002<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXm7wnzFGKF0Pv2ibCKT1khuiagNnVW87RCYfwSPuiatnvWCiaYAPfOu9ibrfQ\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXm7wnzFGKF0Pv2ibCKT1khuiagNnVW87RCYfwSPuiatnvWCiaYAPfOu9ibrfQ.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u738b\u5a01<\/div>\n
\u534e\u5927\u667a\u9020\u526f\u603b\u88c1<\/div>\n
1. \u8d44\u6599\u663e\u793a\u8fd1\u5e74\u6765\u6211\u56fd\u53cc\u80ce\u7684\u53d1\u751f\u7387\u663e\u8457\u4e0a\u5347\uff0c\u4e0e\u76f2\u76ee\u670d\u7528\u4fc3\u6392\u5375\u836f\u7269\u548c\u201c\u5168\u9762\u4e8c\u5b69\u201d\u7684\u653e\u5f00\u6709\u5173\u3002\u4e00\u4e9b\u9ad8\u9f84\u5973\u6027\u4f1a\u9009\u62e9\u901a\u8fc7\u8f85\u52a9\u751f\u6b96\u6280\u672f\u6765\u5b9e\u73b0\u751f\u80b2\u76ee\u7684\uff08\u76ee\u524d\u901a\u8fc7\u8f85\u52a9\u751f\u6b96\u6280\u672f\u53d7\u5b55\u7684\u4eba\u7fa4\u4e2d\uff0c20-30%\u4e3a\u53cc\u80ce\u6216\u591a\u80ce\u598a\u5a20\uff09\uff0c\u8fd9\u4e9b\u56e0\u7d20\u65e0\u7591\u589e\u52a0\u4e86\u5b55\u5987\u4e0e\u80ce\u513f\u7684\u533b\u7597\u98ce\u9669\u3002<\/div>\n
2. \u56fd\u9645\u4e0a\u5df2\u666e\u904d\u5c06NIPT\uff08\u65e0\u521b\u4ea7\u524d\u57fa\u56e0\u68c0\u6d4b\uff09\u5b9a\u4f4d\u4e3a\u4e00\u9879\u9488\u5bf9\u5355\u80ce\u5e38\u89c1\u67d3\u8272\u4f53\u975e\u6574\u500d\u4f53\u7684\u7b5b\u67e5\u6027\u68c0\u6d4b\uff0c\u5bf9\u68c0\u6d4b\u7ed3\u679c\u4e3a\u9ad8\u98ce\u9669\u7684\u5b55\u5987\uff0c\u5b55\u5987\u5e94\u8fdb\u884c\u540e\u7eed\u54a8\u8be2\u53ca\u76f8\u5e94\u7684\u4ea7\u524d\u8bca\u65ad\u3002\u5bf9\u4e8e\u53cc\u80ce\u4e5f\u5e94\u5982\u6b64\u3002\u5982NIPT\u68c0\u6d4b\u7ed3\u679c\u4e3a\u9ad8\u98ce\u9669\uff0c\u90a3\u4e48\u5b55\u5987\u4ecd\u5e94\u8fdb\u884c\u4ecb\u5165\u6027\u624b\u672f\u91c7\u96c6\u80ce\u513f\u7269\u8d28\u8fdb\u884c\u8bca\u65ad\u6027\u68c0\u6d4b\u3002\u6b64\u5916\uff0c\u5176\u4ed6\u7684\u4e34\u5e8a\u4fe1\u606f\uff0c\u7279\u522b\u662f\u8d85\u58f0\u5f71\u50cf\u5b66\u68c0\u67e5\u6709\u52a9\u4e8e\u5bf9\u53cc\u80ce\u60c5\u51b5\u8fdb\u884c\u5224\u65ad\u3002\u8fd9\u5bf9\u4e8e\u5f02\u5375\u53cc\u80ce\u598a\u5a20\uff0c\u5373\u4e24\u4e2a\u80ce\u513f\u9057\u4f20\u76f8\u4f3c\u6027\u5ea6\u5e76\u4e0d\u5b8c\u5168\u76f8\u540c\u7684\u53cc\u80ce\u7c7b\u578b\uff0c\u610f\u4e49\u53ef\u80fd\u66f4\u5927\u3002<\/div>\n
3. \u6839\u636e2016\u5e74\u536b\u8ba1\u59d4\u53d1\u5e03\u7684\u300a\u5b55\u5987\u5916\u5468\u8840\u80ce\u513f\u6e38\u79bbDNA\u4ea7\u524d\u7b5b\u67e5\u4e0e\u8bca\u65ad\u6280\u672f\u89c4\u8303\u300b\uff0c\u53cc\u80ce\u53ca\u591a\u80ce\u598a\u5a20\u4ee5\u53ca\u7ecf\u4f53\u5916\u53d7\u7cbe\u2014\u80da\u80ce\u79fb\u690d\u65b9\u5f0f\u53d7\u5b55\u7684\u5b55\u5987\uff0c\u90fd\u5c5e\u4e8eNIPT\u6280\u672f\u7684\u614e\u7528\u4eba\u7fa4\uff0c\u800c\u975e\u201c\u4e0d\u9002\u7528\u4eba\u7fa4\u201d\u3002\u56e0\u6b64\uff0c\u4e0d\u5c11\u6709\u6761\u4ef6\u7684\u4ea7\u524d\u8bca\u65ad\u673a\u6784\u4f1a\u914c\u60c5\u4e3a\u8fd9\u90e8\u5206\u5b55\u5987\u63d0\u4f9bNIPT\u68c0\u6d4b\u3002\u8fd9\u9879\u7814\u7a76\u5bf9\u6211\u56fd\u4ea7\u524d\u7b5b\u67e5\u4e0e\u8bca\u65ad\u9886\u57df\u4e5f\u5177\u6709\u4e00\u5b9a\u7684\u53c2\u8003\u4ef7\u503c\u3002\u603b\u4e4b\uff0c\u5bf9\u4e8eNIPT\u9002\u7528\u5b55\u5987\u4eba\u7fa4\u4ece\u5355\u80ce\u598a\u5a20\u6269\u5c55\u5230\u53cc\u80ce\u598a\u5a20\uff0c\u76f8\u4fe1\u901a\u8fc7\u56fd\u9645\u540c\u884c\u7684\u5171\u540c\u52aa\u529b\uff0c\u4e34\u5e8a\u7814\u7a76\u6570\u636e\u7684\u4e0d\u65ad\u79ef\u7d2f\uff0c\u5176\u6210\u679c\u6709\u671b\u66f4\u597d\u7684\u6307\u5bfc\u4e34\u5e8a\u5b9e\u8df5\u7684\u5f00\u5c55\uff0c\u6ee1\u8db3\u5e7f\u5927\u5b55\u5987\u5bf9\u4ea7\u524d\u7b5b\u67e5\u4e0e\u8bca\u65ad\u5206\u5b50\u9057\u4f20\u65b0\u6280\u672f\u670d\u52a1\u7684\u9700\u6c42\u3002<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmNnkicXQiaHvjmpf58HDWyjiaVwicicvpvFHxTJwqQMwXsYUmz2N4okEMVYg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmNnkicXQiaHvjmpf58HDWyjiaVwicicvpvFHxTJwqQMwXsYUmz2N4okEMVYg.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u4f0d\u542f\u71b9<\/div>\n
\u4f18\u8fc5\u533b\u5b66CTO<\/div>\n
1. \u8fd1\u5e74\u6765\u968f\u7740\u8f85\u52a9\u751f\u6b96\u6280\u672f\u7684\u666e\u53ca\uff0c\u53cc\u80ce\u598a\u5a20\u7387\u9010\u5e74\u5347\u9ad8\u3002\u53cc\u80ce\u598a\u5a20\u66f4\u5e38\u89c1\u80ce\u513f\u5f02\u5e38\uff0c\u5bf9\u4e8e\u5e38\u89c1\u5e38\u67d3\u8272\u4f53\u4e09\u4f53\u7684\u4ea7\u524d\u7b5b\u67e5\uff0c\u7531\u4e8e\u6807\u5fd7\u7269\u7684\u542b\u91cf\u4e00\u822c\u9ad8\u4e8e\u5355\u80ce\u598a\u5a20\uff0c\u6240\u4ee5\u5047\u9633\u6027\u8f83\u9ad8\uff0c\u76ee\u524d\u5e76\u4e0d\u63a8\u8350\u8840\u6e05\u5b66\u7b5b\u67e5\u624b\u6bb5\u3002\u00a0<\/div>\n
2. \u672c\u6587\u901a\u8fc7\u6536\u96c6\u7684\u6b27\u6d32\u4eba\u7fa4NIPT\u6570\u636e\u548c\u5176\u5b83\u5df2\u53d1\u8868\u7684\u6570\u636e\u8fdb\u884c\u4e86\u835f\u8403\u5206\u6790\uff0c\u5168\u9762\u8bc4\u4f30\u4e86NIPT\u5728\u53cc\u80ce\u598a\u5a20\u4e2d\u7684\u8868\u73b0\u3002\u5bf9\u4e8e21\u4e09\u4f53\uff0c\u603b\u7684DR\u548cFPR\u5206\u522b\u662f98.2%\u548c0.05% \uff0c18\u4e09\u4f53\u7684\u603b\u4f53DR\u548cFPR\u5206\u522b\u662f88.9%\u548c0.03%\uff0c13\u4e09\u4f53\u7684\u75c5\u4f8b\u6570\u8fc7\u5c11\u4e0d\u5177\u5907\u7edf\u8ba1\u610f\u4e49\u3002\u672c\u6587\u4f5c\u8005\u6536\u96c6\u6570\u636e\u768417\u4e2a21\u4e09\u4f53\u300110\u4e2a18\u4e09\u4f53\u548c2\u4e2a13\u4e09\u4f53\u4e2d\uff0c\u53ea\u67091\u4f8b18\u4e09\u4f53\u662f\u5355\u7ed2\u6bdb\u819c\u53cc\u80ce\u598a\u5a20\uff0c\u5176\u4ed6\u6240\u6709\u75c5\u4f8b\u90fd\u662f\u53cc\u7ed2\u6bdb\u819c\u598a\u5a20\uff0c\u7d2f\u53ca1\u4e2a\u80ce\u513f\u3002\u00a0<\/div>\n
3. \u4ee5\u4e0a\u7ed3\u679c\u53ef\u89c1\uff0cNIPT\u5728\u53cc\u80ce\u598a\u5a20\u4e2d\u7684\u8868\u73b0\u867d\u7136\u8fd8\u662f\u7565\u5dee\u4e8e\u5355\u80ce\u598a\u5a20\uff0c\u4f46\u4f18\u4e8e\u5b55\u65e9\u671f\u6216\u4e2d\u671f\u7684\u5f71\u50cf\u548c\u751f\u5316\u7b5b\u67e5\uff0c\u8bf4\u660eNIPT\u5728\u53cc\u80ce\u598a\u5a20\u4e2d\u7684\u5e94\u7528\u8fd8\u662f\u53ef\u884c\u7684\u3002\u8fd9\u4e0e\u6211\u4eec\u4f18\u8fc5\u7684\u7ecf\u9a8c\u76f8\u4f3c\uff0c\u4f46\u6211\u4eec\u4e5f\u8981\u7279\u522b\u63d0\u51fa\u53cc\u80ce\u598a\u5a20\u7684\u6280\u672f\u6311\u6218\uff0c\u6bd4\u5982\u540c\u5375\u53cc\u80ce\u4e0e\u5f02\u5375\u53cc\u80ce\u7684\u80ce\u513f\u6d53\u5ea6\u5dee\u5f02\u5bf9\u4e8e\u7ed3\u679c\u5224\u8bfb\u7684\u5f71\u54cd\uff0c\u53cc\u80ce\u4e2d\u5355\u80ce\u5f02\u5e38\u6216\u53cc\u80ce\u5f02\u5e38\u5bf9\u4e8e\u7ed3\u679c\u5224\u8bfb\u7684\u5f71\u54cd\u7b49\u3002<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXm6T6IaEe5DVGxUKD4wia4tDiaBibNQSAoZ62JFzq8Sickl7iaAHZVp7LqJTQ\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXm6T6IaEe5DVGxUKD4wia4tDiaBibNQSAoZ62JFzq8Sickl7iaAHZVp7LqJTQ.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\nDavid Cram<\/div>\n
\u8d1d\u745e\u57fa\u56e0\u9996\u5e2d\u9057\u4f20\u79d1\u5b66\u5bb6<\/div>\n
1.\u00a0\u6700\u8fd1\u5728UOG\u6742\u5fd7\u53d1\u8868\u7684\u5bf9\u53cc\u80ce\u598a\u5a20\u65e0\u521b\u4ea7\u524d\u68c0\u6d4b\uff08NIPT\uff09\u7684\u62a5\u9053\uff0c\u5bf9\u4e8e\u5e0c\u671b\u77e5\u9053\u5176\u80ce\u513f\u662f\u5426\u643a\u5e26\u5e38\u89c1\u67d3\u8272\u4f53\u75be\u75c5\uff08\u5982\u5510\u6c0f\u7efc\u5408\u75c7\uff09\u7684\u53cc\u80ce\u598a\u5a20\u7684\u5b55\u5987\u6765\u8bf4\u65e0\u7591\u662f\u4e2a\u5229\u597d\u6d88\u606f\u3002<\/div>\n
2. \u57fa\u4e8e\u51713774\u4f8b\u53cc\u80ce\u598a\u5a20\u76848\u9879\u7efc\u5408\u7814\u7a76\u7684meta\u5206\u6790\uff0c\u7ed3\u679c\u663e\u793aNIPT\u5bf9\u5510\u6c0f\u7efc\u5408\u75c7\u7684\u68c0\u6d4b\u5177\u6709\u975e\u5e38\u9ad8\u7684\u7075\u654f\u5ea6\u548c\u7279\u5f02\u6027\uff0c\u5176\u68c0\u6d4b\u6548\u679c\u4e0e\u5355\u80ce\u598a\u5a20\u5b55\u5987\u76f8\u5f53\u3002\u8be5\u7814\u7a76\u8fd8\u8868\u660e\uff0c\u5bf9\u4e8e\u53cc\u80ce\u598a\u5a20\uff0cNIPT\u7684\u4e34\u5e8a\u6548\u7528\u4ea6\u8fdc\u9ad8\u4e8e\u8840\u6e05\u5b66\u7b5b\u67e5\u3002<\/div>\n
3. \u8fd9\u4e9b\u6570\u636e\u4e0e\u76ee\u524d\u5728\u8d1d\u745e\u57fa\u56e0\u8fdb\u884c\u7684\u53cc\u80de\u80ce\u7814\u7a76\u4e00\u81f4\u3002\u57fa\u4e8e\u8fd9\u4e9b\u53d1\u73b0\uff0c\u6211\u4eec\u8ba4\u4e3aNIPT\u9002\u5408\u4f5c\u4e3a\u4ea7\u524d\u7b5b\u67e5\u7684\u4e00\u7ebf\u65b9\u6cd5\uff0c\u51cf\u5c11\u9ad8\u98ce\u9669\u53cc\u80ce\u598a\u5a20\u4e0d\u5fc5\u8981\u7684\u7f8a\u819c\u7a7f\u523a\uff0c\u5e2e\u52a9\u4e34\u5e8a\u533b\u751f\u66f4\u597d\u5730\u7ba1\u7406\u53cc\u80ce\u598a\u5a20\u3002<\/div>\n\n
\n![\"RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmrViaeP1w2aoPvY4S5vZKI6c75HLLMuyiagYJqnJb2wtibE4OnMZuds6Zw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAdOXwOOHVNNDYnvZGIKBXmrViaeP1w2aoPvY4S5vZKI6c75HLLMuyiagYJqnJb2wtibE4OnMZuds6Zw.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u7530\u57c2<\/div>\n
\u5143\u7801\u57fa\u56e0\u521b\u59cb\u4eba<\/div>\n
1. NIPT\u81ea2008\u5e74\u8fdb\u5165\u5e02\u573a\u4ee5\u6765\uff0c\u7ecf\u8fc7\u4e86\u51e0\u4e2a\u9636\u6bb5\u7684\u9636\u6bb5\u7684\u53d1\u5c55\uff0c\u9996\u5148\u662f21\u53f7\u67d3\u8272\u4f53\u4e09\u4f53\u68c0\u6d4b\u7075\u654f\u5ea6\u5f97\u5230\u4e34\u5e8a\u786e\u8ba4\uff0c\u4e4b\u540e\u62d3\u5c55\u523018\u548c13\u4e09\u4f53\u3002\u7136\u540e\u9762\u5bf9\u7684\u6311\u6218\u53d8\u6210\u4e86\u5728\u4e00\u4e9b\u7279\u6b8a\u60c5\u51b5\u4e0b\u662f\u5426\u80fd\u68c0\u6d4b\uff1a\u53cc\u80de\u80ce\u5c31\u662f\u5176\u4e2d\u4e4b\u4e00\uff0c\u8fd8\u6709\u6bd4\u5982\u5fae\u7f3a\u5931\u5fae\u6269\u589e\u7b49\u80ce\u513f\u53ef\u80fd\u51fa\u73b0\u7684\u67d3\u8272\u4f53\u7684\u95ee\u9898\uff0c\u5982\u4f55\u89e3\u51b3\u7684\u95ee\u9898\u3002<\/div>\n
2. \u6b64\u7bc7\u6587\u7ae0\u6240\u62a5\u9053\u7684\u53cc\u80de\u80ce\u8fdb\u884cnipt\u68c0\u6d4b\u7684\u6570\u636e\uff0c\u89e3\u51b3\u4e86\u4e34\u5e8a\u4e0a\u5bf9\u53cc\u80de\u80ce\u8fdb\u884c\u4e3b\u8981\u7684\u4e09\u4f53\u68c0\u6d4b\u7684\u7075\u654f\u5ea6\u7684\u987e\u8651\uff0c\u53ef\u4ee5\u8bf4\u5df2\u7ecf\u57fa\u672c\u4e0a\u8fbe\u5230\u8ddf\u5355\u80ce\u76f8\u540c\u7684\u6548\u679c\uff0cNIPT\u4f7f\u7528\u8303\u56f4\u8fdb\u4e00\u6b65\u6269\u5927\uff0c\u76f8\u4fe1\u5728\u672a\u6765\u5fae\u7f3a\u5931\u548c\u5fae\u6269\u589e\uff0c\u4ee5\u53ca\u5355\u57fa\u56e0\u75c5NIPT\u68c0\u6d4b\u7b49\u5c06\u6709\u66f4\u591a\u5e94\u7528\u5f97\u5230\u4e34\u5e8a\u8ba4\u53ef\u3002<\/div>\n
\u00a0<\/div>\n
\u53c2\u8003\u8d44\u6599\uff1a<\/div>\n
1. Gil MM, Galeva S, Jani J, et al. Screening for trisomies by cfDNA testing of maternal blood in twin pregnancy: update of The Fetal Medicine Foundation results and meta-analysis. Ultrasound Obstet Gynecol. 2019 Jun;53(6):734-742. doi: 10.1002\/uog.20284. Epub 2019 Jun 4.\u00a0<\/div>\n
2. http:\/\/www.sohu.com\/a\/192837736_377327\u300a\u9ec4\u8377\u51e4\uff1a\u4eba\u5de5\u52a9\u5b55\uff0c\u4e00\u6b21\u8fd8\u662f\u53ea\u751f\u4e00\u4e2a\u597d\uff01\u300b.<\/div>\n
3.\u00a0Analysis of cell-free DNA inmaternal blood in screening for aneuploidies: updated meta-analysis. UltrasoundObstet Gynecol 2017;\u00a050: 302 \u2013 314.<\/div>\n
\u00a0<\/div>\n
\u6ce8\uff1a\u5609\u5bbe\u8bc4\u8bba\u90e8\u5206\u4ec5\u4ee3\u8868\u5609\u5bbe\u4e2a\u4eba\u89c2\u70b9\uff0c\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff1b\u673a\u6784\u8f6c\u8f7d\u8bf7\u6ce8\u660e\u6765\u81ea\u201c\u57fa\u56e0\u6167\u201d\u3002<\/div>\n
\u7f16\u8f91\uff1aNicole<\/div>\n
\u6821\u5bf9\uff1aDamine<\/div>\n
\u5ba1\u6838\uff1aMark\u00a0<\/div>\n
\u00a0<\/div>\n
\u76f8\u5173\u63a8\u8350<\/div>\n
\u8fd12\u4e07\u5b57\u7b14\u8bb0\u5e72\u8d27 | \u7b2c\u4e5d\u5c4a\u4e2d\u56fd\u80ce\u513f\u533b\u5b66\u5927\u4f1a<\/a><\/div>\n
\u534e\u5927\/\u8d1d\u745e\/\u8fbe\u5b89\u7b4910\u5bb6\u57fa\u56e0\u4f01\u4e1a\u8c08\u5168\u7403\u534f\u4f5c<\/a><\/div>\n
\u8fd1200\u5bb6\u4ea7\u4e1a\u673a\u6784\u53c2\u4e0e\u7b2c\u4e8c\u5c4a\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\u4f1a\u8bae<\/a><\/div>\n
\u56fd\u5bb6\u536b\u5065\u59d4\uff1a\u9057\u4f20\u54a8\u8be2\u80fd\u529b\u5efa\u8bbe\u4e13\u59d443\u4f4d\u4e13\u5bb6\u540d\u5355<\/a><\/div>\n
\u3010\u8bbf\u8c08\u3011\u00a0\u00a0\u9ec4\u5c1a\u5fd7<\/a>\u00a0\u00a0\u4e01\u6d01<\/a>\u00a0 \u00a0\u59da\u5b8f<\/a>\u00a0\u00a0\u6c88\u4ea6\u5e73<\/a>\u00a0\u00a0\u738b\u5a01<\/a>\u00a0<\/div>\n
\u59dc\u8273\u82b3<\/a>\u00a0\u00a0\u6881\u5fd7\u6e05<\/a>\u00a0\u00a0\u4e8e\u4e16\u8f89<\/a>\u00a0\u00a0\u738b\u827a<\/a>\u00a0\u00a0\u7941\u9e23<\/a>\u00a0<\/div>\n
\u00a0<\/div>\n
\u52a0\u5165\u57fa\u56e0\u6167<\/div>\n
\u884c\u4e1a\u5206\u6790\u5e08<\/div>\n
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\u65b0\u5a92\u4f53\u7f16\u8f91<\/div>\n
\u4e0e\u5927\u5496\u96f6\u8ddd\u79bb\uff0c\u7ad9\u5728\u884c\u4e1a\u8d44\u8baf\u7b2c\u4e00\u7ebf<\/div>\n
\u9500\u552e\/\u4ee3\u7406\u9500\u552e<\/div>\n
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\uff08\u7b80\u5386\u6295\u9012\u90ae\u7bb1\uff1a info@genonet.cn)<\/div>\n
\u00a0<\/div>\n
\u3010\u5173\u4e8e\u57fa\u56e0\u6167\u3011\u57fa\u56e0\u6167\u662f\u4e00\u5bb6\u72ec\u7acb\u7684\u57fa\u56e0\u548c\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u521b\u65b0\u670d\u52a1\u5e73\u53f0\uff0c\u6210\u7acb\u4e8e2016\u5e74\uff0c\u57fa\u4e8e\u884c\u4e1a10\u5e74\u5b9e\u8df5\uff0c\u6211\u4eec\u5efa\u7acb\u4e863000+\u4f01\u4e1a\u5e93\u3001\u667a\u5e93\u548c\u5a92\u4f53\u5e73\u53f0YourMap\uff0c\u4e3a\u5408\u4f5c\u4f19\u4f34\u63d0\u4f9b\u4ea7\u4e1a\u7814\u7a76\u3001\u57f9\u8bad\u54a8\u8be2\u548c\u79d1\u6280\u5a92\u4f53\u7b49\u670d\u52a1\uff0c\u81f4\u529b\u4e8e\u5efa\u7acb\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u4fe1\u606f\u670d\u52a1\u5e73\u53f0\u3002<\/div>\n
\u57fa\u56e0\u6167\u662f\u56fd\u5bb6\u53d1\u6539\u59d4\u300a2019\u5e74\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b\u7f16\u59d4\u7684\u5355\u4f4d\u3001\u5168\u56fd\u536b\u751f\u4ea7\u4e1a\u4f01\u4e1a\u7ba1\u7406\u534f\u4f1a\u7cbe\u51c6\u533b\u7597\u5206\u4f1a\u7406\u4e8b\u7684\u5355\u4f4d\u3001\u300a\u4e34\u5e8a\u751f\u7269\u6837\u672c\u5e93\u63a2\u7d22\u4e0e\u5b9e\u8df5<\/a>\u300b\u7684\u7f16\u59d4\u5355\u4f4d\uff0c\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5b66\u4f1a\u653f\u7b56\u7814\u7a76\u5206\u4f1a\u5e38\u59d4\u7684\u5355\u4f4d\u3001\u6df1\u5733\u5e02\u5065\u5eb7\u4ea7\u4e1a\u53d1\u5c55\u4fc3\u8fdb\u4f1a\u526f\u4f1a\u957f\u5355\u4f4d\uff0c\u53d1\u5e03\u4e86\u300a2019 \u5e74\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b<\/a>\u7b49\u884c\u4e1a\u62a5\u544a\uff0c\u53c2\u4e0e\u7ec4\u7ec7\u9996\u4e2a\u300a\u4e34\u5e8a\u57fa\u56e0\u68c0\u6d4b\u62a5\u544a\u89c4\u8303\u4e0e\u57fa\u56e0\u68c0\u6d4b\u884c\u4e1a\u5171\u8bc6\u300b<\/a>\u53ca\u76f8\u5173\u56e2\u4f53\u6807\u51c6\u53d1\u5e03\uff0c\u53c2\u4e0e\u4e3b\u529e\u4e86\u9996\u5c4a\u6570\u5b57\u5065\u5eb7\u79c1\u8463\u4f1a<\/a>\u3001\u9996\u5c4a\u7ca4\u6e2f\u6fb3\u5927\u6e7e\u533a\u751f\u547d\u5065\u5eb7\u521b\u65b0\u8bba\u575b<\/a>\u3001\u7b2c\u4e00\u5c4a<\/a>\u548c\u7b2c\u4e8c\u5c4a\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\u5927\u4f1a<\/a>\u3002<\/div>\n\n
\n![\"RmFicvQBAkgDwDDlibn6LGMERd60A1XgibkVTEVrPEb1EoTK1HnjticKMtrzWS4eyuZgibs4H2ErBL6cp0GRTKvEAkg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDwDDlibn6LGMERd60A1XgibkVTEVrPEb1EoTK1HnjticKMtrzWS4eyuZgibs4H2ErBL6cp0GRTKvEAkg.jpeg\")
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