\n![\"RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg.gif\")
<\/figure><\/div>\n\n<\/div>\n
<\/figure><\/div>\n\n<\/div>\n<\/div>\n
<\/div>\n
\u5173\u952e\u8bcd\/\u6db2\u4f53\u6d3b\u68c0 MSK<\/div>\n
<\/div>\n
\u5317\u4eac\u65f6\u95f42019\u5e746\u670822\u65e5\uff0c\u7eaa\u5ff5\u65af\u9686\u51ef\u7279\u7433\u764c\u75c7\u4e2d\u5fc3\uff08MSKCC\uff09\u5ba3\u5e03\u65d7\u4e0b\u764c\u75c7\u6db2\u4f53\u6d3b\u68c0\u65b9\u6cd5MSK-ACCESS\u83b7\u5f97\u7ebd\u7ea6\u5dde\u6279\u51c6\uff0c\u7528\u4e8e\u68c0\u6d4b\u4f53\u6db2\u6837\u672c\u7684cfDNA\u7684\u57fa\u56e0\u7a81\u53d8\uff0c\u6709\u6548\u8865\u5145\u4e86MSK-IMPACT<\/a>\u65b9\u6cd5\u3002\u672c\u6587\u5bf9\u5176\u53ca\u540c\u7c7b\u4ea7\u54c1\u3001\u56fd\u5185\u6db2\u4f53\u6d3b\u68c0\u4f01\u4e1a\u53ca\u53d1\u5c55\u7565\u505a\u68b3\u7406\u3002\u6b22\u8fce\u7559\u8a00\u63a2\u8ba8\u3002<\/div>\n
* \u57fa\u56e0\u6167\u6b22\u8fce\u884c\u4e1a\u5206\u6790\u6295\u7a3f\uff1b\u878d\u8d44\u4fe1\u606f\u514d\u8d39\u9996\u53d1\u3002<\/div>\n
<\/div>\n
\n\n
\n![\"RmFicvQBAkgAnq16S4qVWzEdfoadggunapbxeNGibNhL6ZKlwIS8TQWkTgKibvCYaBkgrDlia2ewjZ1GTiarichguSkw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAnq16S4qVWzEdfoadggunapbxeNGibNhL6ZKlwIS8TQWkTgKibvCYaBkgrDlia2ewjZ1GTiarichguSkw.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe1\uff1aMSKCC\uff08\u6765\u6e90\uff1aMSKCC\u5b98\u7f51\uff09<\/div>\n
\u5212\u91cd\u70b9\u5982\u4e0b\uff08\u6587\u7ae0\u8f83\u957f\uff0c\u9605\u8bfb\u65f6\u95f4~15\u5206\u949f\uff09<\/div>\n
1.\u00a0MSK-ACCESS\u662fMSK-IMPACT\u7684\u6709\u6548\u8865\u5145<\/div>\n
2. MSK-IMPACT, F1CDx\u548cGuardant360\u6982\u89c8<\/div>\n
3.\u00a0\u56fd\u518517\u5bb6\u764c\u75c7\u591a\u57fa\u56e0\u68c0\u6d4b\u53ca\u6db2\u4f53\u6d3b\u68c0\u76f8\u5173\u4f01\u4e1a<\/div>\n
4.\u00a0\u80bf\u7624\u6db2\u4f53\u6d3b\u68c0\u6210\u719f\u843d\u5730\u4e34\u5e8a\u8fd8\u6709\u591a\u8fdc\uff1f<\/div>\n
\u00a0<\/div>\n
\u00a0 \u4e00\u00a0MSK-ACCESS\uff1a\u5bf9MSK-IMPACT\u7684\u6709\u6548\u8865\u5145<\/div>\n
\u8be5\u68c0\u6d4b\u65b9\u6cd5\u5168\u79f0\u4e3a\u201ccfDNA\u7684\u4f53\u7ec6\u80de\u7a81\u53d8\u5206\u6790\u201d\uff08Analysis of Circulating cfDNA to Evaluate Somatic Status\u00a0\uff09\uff0c\u7b80\u79f0MSK-ACCESS\u3002<\/div>\n
GSK\u5c1a\u672a\u516c\u5e03\u8be6\u7ec6\u4ea7\u54c1\u8d44\u6599\u3002\u4ee5\u4e0b\u662f\u76f8\u5173\u8981\u70b9\uff1a<\/div>\n
MSK-ACCESS\uff1a\u6cdb\u764c\u79cd\u7efc\u5408\u6db2\u4f53\u6d3b\u68c0<\/div>\n
1. \u9002\u7528\u573a\u666f\uff1a\u5bf9\u4e8e\u80bf\u7624\u7ec4\u7ec7\u96be\u4ee5\u83b7\u5f97\u6216\u8005\u7ec4\u7ec7\u6d3b\u68c0\u96be\u4ee5\u5b9e\u65bd\u7684\u60a3\u8005\uff0c\u6216\u8005\u56e0\u4e3a\u80bf\u7624\u7ec6\u80de\u592a\u5c11\u800cMSK-IMPACT\u65e0\u6548\u65f6\uff08\u8fd9\u4e3b\u8981\u53d1\u751f\u5728\u5728\u665a\u671f\u8f6c\u79fb\u6027\u764c\u75c7\u7684\u4eba\u8eab\u4e0a\uff09\u3002<\/div>\n
2. \u6837\u672c\uff1a\u8840\u6db2\u548c\u5176\u4ed6\u4f53\u6db2\uff08\u4f8b\u5982\u553e\u6db2\u3001\u7cbe\u6db2\uff09\u6837\u672c\uff0c\u63d0\u53d6cfDNA\u3002<\/div>\n
3. \u5206\u6790\uff1a\u57fa\u4e8e\u4f53\u6db2cfDNA\uff0c\u5bf9\u4eceMSK-IMPACT\u4e2d\u6311\u9009\u51fa\u7684129\u79cd\u764c\u75c7\u76f8\u5173\u57fa\u56e0\u8fdb\u884c\u6d4b\u5e8f\u3002<\/div>\n
4. \u7279\u70b9\uff1a<\/div>\n
1\uff09\u76f8\u5bf9\u4e8ectDNA(circulatting tumor DNA\uff0c\u5faa\u73af\u80bf\u7624DNA)\u662f\u4ece\u80bf\u7624\u7ec6\u80de\u8131\u843d\u7684DNA\u7247\u6bb5\u8fdb\u5165\u5916\u5468\u8840\uff0ccfDNA\uff08cell free DNA\uff0c\u7ec6\u80de\u6e38\u79bbDNA\uff09\u662f\u8840\u6db2\u4e2d\u6e38\u79bb\u7684DNA\uff0c\u8303\u56f4\u66f4\u5e7f\uff0c\u4e5f\u5305\u62ec\u4ece\u6b7b\u4ea1\u7684\u80bf\u7624\u7ec6\u80de\u8131\u843d\u7684\u5faa\u73afDNA\u3002\u901a\u8fc7cfDNA\u68c0\u6d4b\u80bf\u7624\u8981\u6c42\u6df1\u5ea6\u66f4\u6df1\uff0c\u7075\u654f\u5ea6\u66f4\u9ad8[4]\u3002<\/div>\n
2\uff09\u76ee\u524dMSK-ACCESS\u5df2\u901a\u8fc7\u4e34\u5e8a\u9a8c\u8bc1\u5e76\u5e94\u7528\u4e8e\u5206\u5b50\u8bca\u65ad\u3002<\/div>\n
3\uff09MSK\u5206\u5b50\u8bca\u65ad\u670d\u52a1\u4e3b\u7ba1Marc Ladanyi\u8868\u793a\uff0cMSK-ACCESS\u6db2\u4f53\u6d3b\u68c0\u5c06\u8865\u5145MSK-IMPACT\u80bf\u7624\u57fa\u56e0\u7ec4\u5206\u6790\u65b9\u6cd5\uff0c\u5e2e\u52a9\u60a3\u8005\u63a5\u53d7\u6700\u5177\u9488\u5bf9\u6027\u7684\u9776\u5411\u7597\u6cd5\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0 \u4e8c\u00a0\u00a0\u00a0\u00a0\u56de\u987eMSK-IMPACT\u3001FoundationOne CDx\u3001Guardant360\u7b49\u80bf\u7624\u591a\u57fa\u56e0\u68c0\u6d4b\u53ca\u6db2\u4f53\u6d3b\u68c0\u65b9\u6cd5<\/div>\n
\u8c08\u5230\u6db2\u4f53\u6d3b\u68c0\uff0c\u6211\u4eec\u5148\u6765\u8c08\u8c08\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u7684\u4e24\u5927\u4ee3\u8868\u673a\u6784\uff0cMSK\u548cFoundation Medicine\u3002\u4ed6\u4eec\u5b9e\u81f3\u540d\u5f52\u5730\u5f00\u521b\u4e86\u6cdb\u764c\u79cd\u591a\u57fa\u56e0\u68c0\u6d4b\uff0c\u4f46\u5747\u57fa\u4e8e\u7ec4\u7ec7\u6837\u672c\u68c0\u6d4b\uff0c\u5e76\u4e14\u4ece\u4e0e\u836f\u5382\u7684\u4f34\u968f\u8bca\u65ad\u4e0e\u8f6c\u5316\u7814\u7a76\u5408\u4f5c\u51fa\u53d1\uff0c\u9010\u6b65\u62d3\u5c55\u5230\u4e34\u5e8a\u5e02\u573a\u3002\u800cGuardant Health\u5219\u8d77\u6b65\u4e8e\u6db2\u4f53\u6d3b\u68c0\uff0c\u4e3b\u8981\u81f4\u529b\u4e8e\u4e34\u5e8a\u5e02\u573a\u7684\u5f00\u53d1\u4e0e\u771f\u5b9e\u4e16\u754c\u7684\u6837\u672c\u79ef\u7d2f\uff0c\u5728\u62db\u80a1\u4e66\u4e2d\u63d0\u5230\u7684\u6db2\u4f53\u6d3b\u68c0\u5e94\u7528\u573a\u666f\uff0c\u4ece\u665a\u671f\u80bf\u7624\u4f34\u968f\u8bca\u65ad\uff08Guardant360\uff09\u3001\u5230\u672f\u540e\u60a3\u8005\u7684\u590d\u53d1\u9884\u6d4b\uff08LUNAR-1\uff09\u3001\u518d\u5230\u80bf\u7624\u9ad8\u53d1\u4eba\u7fa4\u7684\u65e9\u8bca\u65e9\u7b5b\uff08LUNAR-2\uff09\uff0c\u6280\u672f\u548c\u5e02\u573a\u6f5c\u5728\u5bb9\u91cf\u5c42\u5c42\u9012\u8fdb\uff08\u53c2\u8003\u57fa\u56e0\u6167\u76f8\u5173\u6587\u7ae0\u5206\u6790\u53ca\u91c7\u8bbf\uff1a\u6db2\u4f53\u6d3b\u68c0\u4f01\u4e1aGuardant\u4e0a\u5e02\u9996\u65e5\u66b4\u6da869%<\/a>\uff09<\/div>\n
\u00a0<\/div>\n
\u5148\u6765\u8c08\u4e00\u8c08MSK-IMPACT\u3002<\/div>\n
\u5317\u4eac\u65f6\u95f42017\u5e7411\u670816\u65e5\uff0cFDA\u5ba3\u5e03\u6279\u51c6MSK\u7684\u80bf\u7624\u591a\u764c\u79cd\u591a\u57fa\u56e0\u68c0\u6d4b\u5e73\u53f0MSK-IMPACT\u2122\u3002\u5f00\u521b\u4e86\u6cdb\u764c\u79cd\u591a\u57fa\u56e0\u68c0\u6d4b\u4ece\u6982\u5ff5\u9636\u6bb5\u5230\u4e34\u5e8a\u5b9e\u8df5\u9636\u6bb5\u3001\u4e5f\u9884\u793a\u5f00\u542fIVD\u548cLDT\u521b\u65b0\u5ba1\u6279\u4e4b\u8def\u3002<\/div>\n
MSK-IMPACT\uff1a\u6cdb\u764c\u79cd\u7ec4\u7ec7\u6837\u672c\u57fa\u56e0\u68c0\u6d4b<\/div>\n
\u00a0<\/div>\n
1. \u8d77\u6e90\uff1aMSK-IMPACT\u81ea2014\u5e741\u6708\u8d77\u88abMSK\u7528\u4e8e\u5236\u5b9a\u665a\u671f\u764c\u75c7\u60a3\u8005\u7684\u6cbb\u7597\u65b9\u6848\u3002\u68c0\u6d4b\u8303\u56f4\u4ece2014\u5e74\u7684341\u4e2a\u57fa\u56e0\u6269\u5c55\u52302017\u5e74\u7684468\u4e2a\u57fa\u56e0\u3002\u57282017\u5e74\u521d\u5728\u300aNature Medicine\u300b\u6742\u5fd7\u4e0a\u53d1\u886810336\u4f8bMSK-IMPACT\u80bf\u7624\u60a3\u8005\u6d4b\u5e8f\u7814\u7a76\u3002<\/div>\n
2.\u7528\u9014\uff1a\u76f8\u5bf9\u4e8e2016\u5e74FDA\u6279\u51c6 FoundationFocus\u2122 CDxBRCA\u76f8\u6bd4\u6709\u7740\u672c\u8d28\u7a81\u7834\uff0c\u540e\u8005\u68c0\u6d4bBRCA\u57fa\u56e0\u7b5b\u9009\u51fa\u5bf9\u65b0\u836fRubraca\u9002\u914d\u7684\u5375\u5de2\u764c\u60a3\u8005\u3002\u800cMSK-IMPACT\u8986\u76d6468\u4e2a\u57fa\u56e0\u76f8\u5173\u7684\u591a\u4e2a\u764c\u79cd\u3002<\/div>\n
3. \u5206\u6790\u65b9\u6cd5\uff1a\u9488\u5bf9\u80bf\u7624\u60a3\u8005\u7684FFPE\uff08\u798f\u5c14\u9a6c\u6797\u56fa\u5b9a\u7684\u77f3\u8721\u5305\u57cb\u80bf\u7624\u7ec4\u7ec7\uff09\u6837\u672c\u548c\u6b63\u5e38\u5bf9\u7167\u6837\u672c\uff0c\u57fa\u4e8eIllumina HiSeq\u2122 2500 \u4e8c\u4ee3\u6d4b\u5e8f\u4eea\u5e73\u53f0\uff0c\u4ece468\u4e2a\u57fa\u56e0\u76846284\u4e2a\u5916\u663e\u5b50\u4e2d\u68c0\u6d4b\u4f53\u7ec6\u80de\u7a81\u53d8\uff08SNV\uff09\u3001\u5c0f\u7247\u6bb5\u63d2\u5165\u7f3a\u5931\uff08Indel\uff09\u548c\u5fae\u536b\u661f\u7a81\u53d8\u7b49\u3002433\u4e2a\u6837\u672c\u4e2d\uff0c96.5%\u7684\u6837\u672c\u6d4b\u5e8f\u2265200X\uff0c432\u4e2a\u6837\u672c\u88ab\u6210\u529f\u68c0\u6d4b\u51fa\u3002<\/div>\n
4. \u7279\u8272\uff1a<\/div>\n
1\uff09\u751f\u7269\u4fe1\u606f\uff1a\u91cd\u70b9\u662f\u5bf9\u4e8e\u68c0\u6d4b\u5230\u7684\u57fa\u56e0\u7a81\u53d8\u7684\u8fc7\u6ee4\u548c\u6ce8\u91ca\uff1b<\/div>\n
2\uff09\u6570\u636e\u5171\u4eab\uff1a\u901a\u8fc7MSK-IMPACT\u68c0\u6d4b\u6536\u96c6\u7684\u6570\u636e\uff0c\u90fd\u5c06\u901a\u8fc7MSK\u5f00\u53d1\u7684\u6570\u636e\u5e93cBioPortal\uff08\u5171\u4eab\u7f51\u5740\uff1ahttp:\/\/cbioportal.org\/msk-impact\uff09\u63d0\u4f9b\u7ed9\u79d1\u5b66\u540c\u4ec1\uff08\u60a3\u8005\u7684\u8eab\u4efd\u7b49\u8bc6\u522b\u4fe1\u606f\u88ab\u5220\u9664\uff0c\u4f46\u5305\u62ec\u57fa\u672c\u7684\u4e34\u5e8a\u6570\u636e\uff09\uff0c\u4e5f\u5c06\u901a\u8fc7\u516b\u4e2a\u524d\u6cbf\u764c\u75c7\u4e2d\u5fc3\u53c2\u4e0e\u7684 AACR\u4e3b\u5bfc\u7684GENIE\u9879\u76ee\u5171\u4eab\u3002<\/div>\n
\u66f4\u591a\u8be6\u60c5\u53ca\u4e13\u5bb6\u70b9\u8bc4\uff0c\u8bf7\u53c2\u8003\u6587\u672b\u63a8\u8350\u7684\u57fa\u56e0\u6167\u76f8\u5173\u6587\u7ae0\u3002<\/div>\n
\u00a0<\/div>\n
\u518d\u6765\u770b\u4e00\u770bFoundationOne CDx\u3002<\/div>\n
\u7d27\u63a5\u774015\u5929\u540e\uff0c\u4e5f\u5c31\u662f\u5317\u4eac\u65f6\u95f42017\u5e7412\u67081\u65e5\uff0c\u7531Foundation Medicine\uff08FMI\uff09\u5f00\u53d1\u7684FoundationOne CDx\uff08F1CDx\uff09\u88abFDA\u548cCMS\uff08\u7f8e\u56fd\u533b\u7597\u4fdd\u9669\u548c\u533b\u7597\u8865\u52a9\u670d\u52a1\u4e2d\u5fc3\uff09\u540c\u65f6\u6279\u51c6\u3002\u636e\u79f0\uff0c\u8fd9\u662f\u6279\u51c6\u7684\u9996\u4e2a\u7a81\u7834\u6027\u7684\u591a\u764c\u79cd\u4f34\u968f\u8bca\u65ad\uff08CDx\uff09\u57fa\u56e0\u68c0\u6d4b\u5e73\u53f0\u3002<\/div>\n
\u00a0<\/div>\n
FoundationOne CDx\uff08F1CDx\uff09\uff1a\u6cdb\u764c\u79cd\u7ec4\u7ec7\u6837\u672c\u4f34\u968f\u8bca\u65ad\u57fa\u56e0\u68c0\u6d4b<\/div>\n
1\uff09324\u4e2a\u57fa\u56e0\u9057\u4f20\u7a81\u53d8\u548c\u4e24\u4e2a\u57fa\u56e0\u7ec4\u7279\u5f81\u76f8\u5173\u5b9e\u4f53\u7624\u3002<\/div>\n
2\uff09\u901a\u8fc7\u6bd4\u8f83F1CDx\u548c\u4e4b\u524dFDA\u6279\u51c6\u7684\u4f34\u968f\u8bca\u65ad\u6d4b\u8bd5\uff0c\u51c6\u786e\u7387\u8fbe\u523094.6\uff05\u3002<\/div>\n
3\uff09\u63d0\u53d6FFPE\u80bf\u7624\u7ec4\u7ec7\u7684DNA\uff0c\u6784\u5efa\u5168\u57fa\u56e0\u7ec4\u6587\u5e93\uff0c\u91c7\u7528Illumina HiSeq 4000\u5e73\u53f0\u8fdb\u884c\u6d4b\u5e8f\u3002\u5bf9324\u4e2a\u6d4b\u5e8f\u57fa\u56e0\u6570\u636e\u8fdb\u884c\u5206\u6790\uff0c\u65e8\u5728\u53d1\u73b0\u78b1\u57fa\u7f6e\u6362\u3001\u63d2\u5165\u6216\u7f3a\u5931\u3001\u62f7\u8d1d\u6570\u53d8\u5f02\u3001\u57fa\u56e0\u91cd\u6392\u3001\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\uff08MSI\uff09\u548c\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\uff08TMB\uff09\u3002<\/div>\n
4\uff09\u7406\u8bba\u4e0a\u8986\u76d6\u5230\u5168\u90e8\u5b9e\u4f53\u7624\uff08\u8089\u7624\u9664\u5916\uff09\uff0c\u5728\u4e94\u5927\u764c\u79cd\uff08\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3001\u9ed1\u8272\u7d20\u7624\u3001\u4e73\u817a\u764c\u3001\u7ed3\u76f4\u80a0\u764c\u3001\u5375\u5de2\u764c\uff09\u3001FDA\u6279\u51c6\u768417\u4e2a\u9776\u5411\u836f\u7684\u4f34\u968f\u8bca\u65ad\u30018\u4e2a\u4f34\u968f\u8bca\u65ad\u9002\u5e94\u75c7\u4e2d\u8fdb\u884c\u4e86\u4e34\u5e8a\u9a8c\u8bc1\u3002<\/div>\n\n
\n![\"RmFicvQBAkgAnq16S4qVWzEdfoadggunaSSya0YWFXPMx9qHgWicDEyRZoaiagWM1wCjwmAIPT8tywc3Pp3Q3NKrg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAnq16S4qVWzEdfoadggunaSSya0YWFXPMx9qHgWicDEyRZoaiagWM1wCjwmAIPT8tywc3Pp3Q3NKrg.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe2\uff1aF1CDX\u5bf9\u5e94\u7684\u4e94\u79cd\u764c\u79cd\u751f\u7269\u6807\u8bb0\u7269\u4ee5\u53ca\u4f34\u968f\u8bca\u65ad\u5bf9\u5e94\u7684\u836f\u7269\uff08\u6765\u6e90\uff1a\u516c\u4f17\u53f7\u201c\u88d5\u7b56\u751f\u7269\u201d\uff09<\/div>\n
5\uff09FMI\u7684\u5408\u4f5c\u7b56\u7565\uff0c\u5728\u672c\u571f\u4e3b\u8981\u548c\u836f\u5382\uff08\u4f8b\u5982\u8bfa\u534e\uff09\u5408\u4f5c\u5f00\u53d1\u80bf\u7624CDx\uff0c\u548c\u6570\u636e\u5206\u6790\u516c\u53f8\uff08\u4f8b\u5982Flatiron Health\uff09\u5408\u4f5c\u4e3a\u751f\u547d\u79d1\u5b66\u516c\u53f8\u764c\u75c7\u6cbb\u7597\u76f8\u5173\u7684\u5206\u6790\u5de5\u5177\u4ea7\u54c1\uff1b\u5728Roche\u6536\u8d2d\u540e\u52a0\u5927\u8fdb\u5165\u4e2d\u56fd\uff0c\u57282018\u5e74\u5e95\u901a\u8fc7\u8fea\u5b89\u8bca\u65ad\u5408\u4f5cF1CDx\u5728\u4e2d\u56fd\u4e0a\u5e02\u3002<\/div>\n
\u00a0<\/div>\n
\u6700\u540e\u804a\u4e00\u804aGuardant360\u3002<\/div>\n
\u4e0a\u9762\u63d0\u5230\uff0cGuardant Health\uff08NASDAQ:GH\uff09\u4e0d\u540c\u4e8eFMI\u548cGSK\uff0c\u4e13\u6ce8\u4e8e\u6db2\u4f53\u6d3b\u68c0\u30022017\u5e745\u6708\uff0cGuardant Health\u5ba3\u5e03\u65d7\u4e0b\u7684Guardant360\u4ea7\u54c1\u5df2\u83b7\u5f97\u7ebd\u7ea6\u5dde\u7684\u4e34\u5e8a\u5b9e\u9a8c\u5ba4\u8bc4\u4f30\u9879\u76ee\uff08CLEP\uff09\u6279\u51c6\uff0c\u6210\u4e3a CLEP\u6279\u51c6\u7684\u9996\u4e2a\u7efc\u5408\u6db2\u4f53\u6d3b\u68c0\u4ea7\u54c1\uff0c\u5728Guardant Health\u4e0a\u5e02\u4e4b\u9645\uff08\u8be6\u60c5<\/a>\uff09\uff0c\u81ea2014\u5e74\u52302018\u5e747\u6708\uff0cGuardant360\u6837\u672c\u91cf\u5df2\u8d85\u8fc770,000\u4efd\u3002<\/div>\n
\u00a0<\/div>\n
Guardant360\uff1a\u764c\u75c7\u6db2\u4f53\u6d3b\u68c0<\/div>\n
\u5728\u6211\u4eec\u67e5\u9605Guardant360\u4ea7\u54c1\u65f6\uff0c\u9c9c\u6709\u4e2d\u6587\u5a92\u4f53\u62a5\u9053\uff0cGuardant Health\u5b98\u7f51\u53ca\u5176\u7b80\u6d01\uff0c\u53ef\u4ee5\u770b\u51fa\u6781\u5177\u4ea7\u54c1\u8bbe\u8ba1\u7406\u5ff5\u3002<\/div>\n
1. \u5e94\u7528\u573a\u666f<\/div>\n
1\uff09\u5728\u4e00\u7ebf\u6cbb\u7597\u4e4b\u524d\uff0c\u901a\u8fc7Guardant360\u6db2\u4f53\u6d3b\u68c0\u6307\u5bfc\u6cbb\u7597\u65b9\u6cd5\u9009\u62e9\u3002<\/div>\n
2\uff09\u764c\u75c7\u6cbb\u7597\u8fc7\u7a0b\u4e2d\uff08At Progression\uff09\uff0c\u901a\u8fc7\u57fa\u56e0\u7ec4\u56fe\u8c31\u5e2e\u52a9\u627e\u5230\u6cdb\u764c\u75c7\u6cbb\u7597\u65b9\u6cd5\u548c\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/div>\n
2. \u5206\u6790<\/div>\n
1\uff09\u591a\u79cd\u5b9e\u4f53\u7624\u76f8\u5173\u768473\u4e2a\u76f8\u5173\u57fa\u56e0\uff08\u89c1\u4e0b\u8868\uff09\u6d4b\u5e8f\u53ca\u751f\u7269\u4fe1\u606f\u5206\u6790\u3002\u5176\u4e2d\u5305\u62ec7\u9879\u6307\u5357\u63a8\u8350\u7684\u9884\u6d4b\u751f\u7269\u6807\u8bb0\u7269\uff08EGFR\u3001ALK\u3001ROS1\u3001BRAF\u3001RET\u3001MET\u3001ERBB2\uff0c\u5373G7\u751f\u7269\u6807\u8bb0\u7269\u548c1\u79cd\u9884\u540e\u6807\u8bb0\u7269\uff08KRAS\uff09\u3002<\/div>\n
2\uff09\u914d\u5907\u76f8\u5e94App\u3002\u6574\u4f53\u5468\u671f\u662f7\u4e2a\u81ea\u7136\u65e5\u3002<\/div>\n\n
\n![\"RmFicvQBAkgAnq16S4qVWzEdfoadggunafhwVdm93pibfJxQDGiaGRZibtCKZ0sPk1DbWsicTVJ4bicaqvAYw4wPxFjg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgAnq16S4qVWzEdfoadggunafhwVdm93pibfJxQDGiaGRZibtCKZ0sPk1DbWsicTVJ4bicaqvAYw4wPxFjg.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe3\uff1aGuardant360\u6db2\u4f53\u6d3b\u68c0\u4ea7\u54c1\u7684\u57fa\u56e0\u5217\u8868\uff08\u6765\u6e90\uff1aGuardant Health\u5b98\u7f51\uff09<\/div>\n
3. \u7ed3\u679c<\/div>\n
\u6839\u636e\u5b98\u7f51\uff0c\u4e00\u9879323\u540d\u8d39\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u7814\u7a76\u4e2d[6]\uff0c\u53d1\u73b044%\u7684\u60a3\u8005\u65e0\u6cd5\u4ece\u7ec4\u7ec7\u6837\u672c\u4e2d\u83b7\u53d6\u57fa\u56e0\u7ec4\u4fe1\u606f\uff08\u9700\u8981\u6db2\u4f53\u6d3b\u68c0\uff09\uff0c\u63a5\u53d7\u6db2\u4f53\uff08\u8840\u6d46\uff09\u6d3b\u68c0\u548c\u6d4b\u5e8f\u5206\u6790\u768442\u540d\u60a3\u8005\u4e2d\uff0c\u670936\u540d\uff0885.7\uff05\uff09\u901a\u8fc7\u5efa\u8bae\u7684\u6cbb\u7597\u65b9\u5f0f\u5b9e\u73b0\u4e86\u5b8c\u5168\u6216\u90e8\u5206\u7684\u5eb7\u590d\u3002<\/div>\n
\u00a0<\/div>\n
\u6839\u636eAACR\u7684NILE\u7684\u8bc4\u4f30\u6570\u636e\uff08\u6458\u89814460\uff09\uff0c\u6765\u81ea\u5317\u7f8e28\u4e2a\u4e2d\u5fc3\u3002\u6240\u6709282\u540d\u672a\u7ecf\u6cbb\u7597\u7684NSCLC\u60a3\u8005\u6837\u672c\u5747\u4f7f\u7528Guardant 360\u8fdb\u884c\u6807\u51c6\u7ec4\u7ec7\u57fa\u56e0\u5206\u578b\u548ccfDNA\u5206\u6790\u3002\u7ed3\u679c\u663e\u793a\uff1a<\/div>\n
1\uff09\u6db2\u4f53\u6d3b\u68c0\u53ef\u5c06G7\u68c0\u6d4b\u9891\u7387\u63d0\u9ad848\uff05\uff1b<\/div>\n
2\uff09\u5bf9\u4e8e\u5177\u6709\u7ecf\u6279\u51c6\u7684\u6cbb\u7597\u836f\u7269\u7684\u56db\u79cd\u751f\u7269\u6807\u5fd7\u7269\uff08EGFR\u3001ALK\u3001ROS1\u548cBRAF\uff09\u7684\u6db2\u4f53\u6d3b\u68c0\u6d4b\u8bd5\u7ed3\u679c\u4e0e\u7ec4\u7ec7\u68c0\u6d4b\u7ed3\u679c\u4e00\u81f4\uff0c100\uff05\u9633\u6027\u9884\u6d4b\u503c\uff1b<\/div>\n
3\uff09\u5468\u671f\u76f8\u5bf9\u7ec4\u7ec7\u68c0\u6d4b\u663e\u8457\u7f29\u77ed\uff089\u5929 vs 15\u5929\uff09\uff08\u7f16\u8005\u6ce8\uff1a\u6b64\u5904\u5468\u671f\u6bd4\u5b98\u7f51\u591a2\u5929\uff09\uff1b<\/div>\n
4\uff09\u5047\u9634\u6027\u7387\u8f83\u9ad8\u300250\uff05\u7684ROS1\u91cd\u6392\u65e0\u6cd5\u68c0\u6d4b\u5230\u3002<\/div>\n
\u00a0<\/div>\n
4. \u4ecd\u5904\u4e8e\u7814\u53d1\u6295\u5165\uff08\u201c\u70e7\u94b1\u201d\uff09\u9636\u6bb5<\/div>\n
1\uff09Guardant Health\u76842018\u5e74\u8d22\u62a5[7]\u63d0\u5230\uff0c\u5df2\u548c\u963f\u65af\u5229\u5eb7\uff08AZ\uff09\u5408\u4f5c\u5f00\u53d1\u57fa\u4e8eGuardant360\u7684Tagrisso\u4f34\u968f\u8bca\u65ad\uff08\u8fd8\u5305\u62ec\u57fa\u4e8eGuardantOMNI\u7684Imfinzi\u4f34\u968f\u8bca\u65ad\uff09\u3002<\/div>\n
2\uff092018\u5e74\u6536\u51659.06\u4ebf\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957f82%\uff1b\u5176\u4e2d\u7cbe\u51c6\u80bf\u7624\u68c0\u6d4b\uff08\u4e3b\u8981\u662fGuardant360\u548cGuardantOMNI\uff09\u5360\u6bd487%\uff0c\u9500\u552e\u989d\u4e3a7.84\u4ebf\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957f86%\u3002\u4f46\u589e\u957f\u539f\u56e0\u4e3b\u8981\u662f\u533b\u4fdd\u653f\u7b56\u548cGuardantOMNI\u9500\u552e\u589e\u52a0\uff08\u8bf4\u660eGuardant360\u9500\u91cf\u5e76\u672a\u589e\u957f\u6216\u660e\u663e\u589e\u957f\uff09\u3002<\/div>\n
3\uff09\u540c\u65f6\u7531\u4e8e\u6574\u4f53\u4ea7\u4e1a\u5904\u4e8e\u7814\u53d1\u9636\u6bb5\uff082018\u5e74\u7814\u53d1\u6210\u672c\u7ea6\u4e3a5.0\u4ebf\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957f100%\uff09\uff0c2018\u5e74\u5ea6\u51c0\u5229\u4e3a-8.51\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u52a04.42%\u3002<\/div>\n
4\uff09\u836f\u5382\u4e1a\u52a1\u589e\u957f\u670d\u52a1\u660e\u663e\u9ad8\u4e8e\u4e34\u5e8a\uff0865% vs 15%\uff09\u3002<\/div>\n
\u00a0<\/div>\n
\u5728\u80bf\u7624\u6db2\u4f53\u6d3b\u68c0\u9886\u57df\uff0c\u9664\u4e86MSK\uff0cFoundation Medicine\u548cGuardant Health\uff0c\u8fd8\u5305\u62ec\u660e\u661f\u516c\u53f8Grail\uff0c\u65e9\u671f\u4f5c\u4e3aIllumina\u7684\u5b50\u516c\u53f8\uff0c\u53d7\u5230\u8c37\u6b4c\u3001\u817e\u8baf\u3001BMS\u7b49\u201c\u5de8\u5934\u201d\u516c\u53f8\u603b\u8ba116\u4ebf\u7f8e\u91d1\u7684\u6295\u8d44\u3002\u7814\u53d1\u901f\u5ea6\u76f8\u5bf9\u8f83\u6162\uff0c\u4e5f\u5f15\u5f972017\u5e74\u8d77\u4eceillumina\u9010\u6e10\u5265\u79bb\u51fa\u6765\u3002\u5386\u7ecf3\u5e74\uff0c2019\u5e745\u6708\uff0c\u5176\u591a\u764c\u79cd\u65e9\u671f\u68c0\u6d4b\u4ea7\u54c1\u624d\u88abFDA\u6279\u51c6\u4e3a\u7a81\u7834\u6027\u8bbe\u5907\u3002<\/div>\n
\u6b64\u5916\uff0c2018\u5e7411\u6708\uff0cMDxHealth\u5ba3\u5e03\u65d7\u4e0b\u9488\u5bf9\u524d\u5217\u817a\u764c\u7684SelectMDx\u68c0\u6d4b\u83b7\u5f97\u7ebd\u7ea6\u5dde\u536b\u751f\u90e8\u5df2\u6279\u51c6[8]\u3002\u5176\u4ed6\u516c\u53f8\u8fd8\u5305\u62ecFreenome\u7b49\uff0c\u5728\u57fa\u56e0\u6167\u540e\u7eed\u53d1\u5e03\u7684\u300a\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u884c\u4e1a\u62a5\u544a\u300b\u4e2d\u5c06\u505a\u8be6\u8ff0\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0 \u4e09 \u00a0 \u56fd\u5185\u6cdb\u764c\u79cd\u591a\u57fa\u56e0\u68c0\u6d4b\u53ca\u6db2\u4f53\u6d3b\u68c0\u4f01\u4e1a<\/div>\n
\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u4f5c\u4e3a\u56fd\u5185\u57fa\u56e0\u884c\u4e1a\u6700\u70ed\u95e8\u7684\u8d5b\u9053\uff08\u8be6\u89c1\u300a2019\u5e74\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b<\/a>\uff09\uff0c\u867d\u7136\u6709\u5c40\u90e8\u5dee\u5f02\u5316\uff0c\u4f46\u5927\u90e8\u5206\u5904\u4e8e\u540c\u8d28\u5316\u6fc0\u70c8\u7ade\u4e89\u9636\u6bb5\u3002<\/div>\n
\u4ece\u5ba1\u6279\u89d2\u5ea6\uff0cNMPA\uff08\u4ee5\u53ca\u524dCFDA\uff09\u4ec5\u6279\u51c6\u4e86\u5305\u62ec\u4e16\u548c\u57fa\u56e0\u3001\u71c3\u77f3\u533b\u5b66\u3001\u8bfa\u79be\u81f4\u6e90\u7b49\u5c11\u6570\u51e0\u5bb6\u5382\u5546\u7684\u80bf\u7624NGS\u591a\u57fa\u56e0\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08\u5bf9\u6bd4<\/a>\uff09\uff0c\u4ee5\u53ca\u827e\u5fb7\u751f\u7269\u7684\u80bf\u7624PCR\u57fa\u56e0\u68c0\u6d4b\u8bd5\u5242\u76d2\u3002\u83b7\u6279\u7684\u8bd5\u5242\u76d2\u68c0\u6d4b\u7684\u57fa\u56e0\u4e2a\u6570\u8f83\u5c11\uff0c\u9002\u5e94\u75c7\u57fa\u672c\u96c6\u4e2d\u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u3002\u76ee\u524d\u76f8\u5173\u90e8\u95e8\u6b63\u5728\u63a8\u52a8\u80bf\u7624\u57fa\u56e0\u5927Panel\u7684\u7814\u53d1\u548c\u5ba1\u6279\uff0c\u6709\u671b\u843d\u5730\u3002<\/div>\n
\u00a0<\/div>\n
\u4ece\u4ea7\u4e1a\u89d2\u5ea6\uff0c\u76ee\u524d\u805a\u7126\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\uff08\u542b\u6db2\u4f53\u6d3b\u68c0\uff09\u7684\u4f01\u4e1a\u5c42\u6b21\u4e0d\u9f50\uff0c\u5305\u542b\u7740\u4e0d\u5c11\u4ee5\u8425\u9500\u548c\u5305\u88c5\u4e3a\u5671\u5934\u7684\u8de8\u754c\u8fdb\u5165\u7684\u673a\u6784\uff0c\u5938\u5927\u670d\u52a1\u8d28\u91cf\u3002\u9700\u8981\u76f8\u5e94\u7684\u76d1\u7ba1\uff0c\u907f\u514d\u57fa\u56e0\u884c\u4e1a\u7684\u201c\u9b4f\u5219\u897f\u4e8b\u4ef6\u201d\u53d1\u751f\u3002<\/div>\n
\u4ee5\u4e0b\u5217\u4e3e\u56fd\u5185\u4e3b\u8981\u7684\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u4f01\u4e1a\uff08\u4e0d\u5b8c\u5168\u7edf\u8ba1\uff0c\u6392\u540d\u4e0d\u5206\u5148\u540e\uff0c\u66f4\u591a\u4f01\u4e1a\u6b22\u8fce\u7559\u8a00\u8865\u5145\uff09\u66f4\u591a\u8be6\u60c5\u8bf7\u53c2\u8003\u57fa\u56e0\u6167\u5373\u5c06\u53d1\u5e03\u7684\u300a\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u884c\u4e1a\u62a5\u544a\u300b<\/div>\n
\u00a0<\/div>\n
\u71c3\u77f3\u533b\u5b66<\/div>\n
\u56fd\u5185\u9996\u4e2a\u83b7\u5f97CFDA\u6279\u51c6\u7684\u80bf\u7624\uff08\u4e3b\u8981\u9488\u5bf9NSCLC\uff09NGS\u591a\u57fa\u56e0\u68c0\u6d4b\u8bd5\u5242\u76d2\u7684\u5382\u5546\uff0c\u603b\u878d\u8d44\u8d85\u8fc713\u4ebf\u5143\u4eba\u6c11\u5e01\uff08\u6b64\u8d5b\u9053\u878d\u8d44\u6570\u76ee\u6700\u5927\u7684\u4f01\u4e1a\uff09\u3002\u521b\u59cb\u4eba\u6c49\u96e8\u751f\u62e5\u6709\u534f\u548c\u7ec6\u80de\u751f\u7269\u5b66\u7855\u58eb\u3001\u54e5\u4f26\u6bd4\u4e9a\u5927\u5b66MBA\u548c\u5317\u6781\u5149\u6295\u8d44\u7ecf\u7406\u7684\u4e09\u91cd\u80cc\u666f\u3002\u6218\u7565\u662f\u4ece\u4e34\u5e8a\u4eba\u7fa4\u7684\u80bf\u7624\u8bca\u7597\u8f85\u52a9\u5230\u5065\u5eb7\u4eba\u7fa4\u65e9\u7b5b\uff0c\u8fd9\u70b9\u4ee5\u4e0b\u5927\u90e8\u5206\u4f01\u4e1a\u4e0e\u6b64\u7c7b\u4f3c\u3002<\/div>\n
\u00a0<\/div>\n
\u4e16\u548c\u57fa\u56e0<\/div>\n
\u83b7\u5f97CFDA\u6279\u51c6\u7684\u80bf\u7624\uff08\u4e3b\u8981\u9488\u5bf9NSCLC\uff09NGS\u591a\u57fa\u56e0\u68c0\u6d4b\u8bd5\u5242\u76d2\u7684\u5382\u5546\u30022008\u5e74\u5728\u52a0\u62ff\u5927\u521b\u7acb\u800c\u540e2013\u5e74\u843d\u5730\u6c5f\u82cf\u5357\u4eac\uff0c\u76f8\u6bd4\u624e\u5806\u7684\u5317\u4eac\u548c\u5e7f\u4e1c\u5730\u533a\uff0c\u5177\u6709\u5730\u7406\u8d44\u6e90\u4f18\u52bf\uff0c\u83b7\u5f97\u5357\u4eac\u6c5f\u5317\u65b0\u533a\u7684\u91cd\u70b9\u652f\u6301\u548c\u653f\u5e9c\u57fa\u91d1\u6295\u8d44\u3002<\/div>\n
\u00a0<\/div>\n
\u534e\u5927\u57fa\u56e0\uff08SZ.300670\uff09<\/div>\n
\u6b63\u5728\u52a0\u901f\u63a8\u8fdb\u7814\u53d1\u80bf\u7624NGS\u57fa\u56e0\u68c0\u6d4b\u8bd5\u5242\u76d2\u3002\u4f18\u52bf\u662f\u4e0a\u4e0b\u6e38\u7684\u7814\u53d1\u53ca\u751f\u4ea7\u6210\u672c\uff08\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u53ca\u534e\u5927\u667a\u9020\uff09\u7684\u8d44\u6e90\u4f18\u52bf\uff0c\u4eab\u53d7\u5f53\u524d\u653f\u7b56\u7ea2\u5229\u540c\u65f6\u4e5f\u7f3a\u5c11\u81ea\u7531\u5e02\u573a\u7ade\u4e89\u4e0b\u7684\u52a0\u901f\u5ea6\u3002\u4ece2018\u5e74\u8d22\u62a5\u4e0a\uff0c\u80bf\u7624\u4ea7\u54c1\u8425\u6536\u4ec5\u536014%\uff08\u76f8\u6bd4\u751f\u80b2\u5065\u5eb754%\uff09\uff0c\u540c\u6bd4\u4e0b\u964d56%\uff1b\u540c\u65f6\u4e0e\u963f\u65af\u5229\u5eb7\u5408\u4f5c\u63a8\u52a8\u6297\u764c\u8f6c\u79fb\u6027\u4e73\u817a\u764c\u9776\u5411\u836f\u7269\u5965\u62c9\u5e15\u5c3c\u4e0a\u5e02\u3002\u57fa\u4e8e\u5408\u4f5c\u7684BRCA1\/2\u57fa\u56e0\u7a81\u53d8\u68c0\u6d4b\u8bd5\u5242\u76d2\u4e8e2018 \u5e747\u6708\u901a\u8fc7NMPA\u7684\u521b\u65b0\u533b\u7597\u5668\u68b0\u7279\u522b\u5ba1\u6279\u7533\u8bf7\u3002\u76ee\u524d\u6b63\u52a0\u901f\u8fdb\u884cPanel\u8bd5\u5242\u76d2\u62a5\u8bc1\u3002<\/div>\n
\u00a0<\/div>\n
\u8bfa\u79be\u81f4\u6e90<\/div>\n
\u83b7\u5f97CFDA\u6279\u51c6\u7684\u80bf\u7624\uff08\u4e3b\u8981\u9488\u5bf9NSCLC\uff09NGS\u591a\u57fa\u56e0\u68c0\u6d4b\u8bd5\u5242\u76d2\u7684\u5382\u5546\u3002\u65e9\u671f\u4e13\u6ce8\u4e8e\u79d1\u6280\u670d\u52a1\uff0c\u878d\u8d44\u8f83\u665a\uff082016\u5e74\u9996\u8f6e\uff09\uff0c\u7ee7\u800c\u6295\u5165\u80bf\u7624\u8d5b\u9053\u201c\u540e\u6765\u5c45\u4e0a\u201d\u3002\u76ee\u524d\u6574\u4f53\u516c\u53f8\u5728\u4e0a\u5e02\u51c6\u5907\u9636\u6bb5\uff0c\u540c\u65f6\u5e03\u5c40\u7f8e\u56fd\uff08\u52a0\u5dde\uff09\u3001\u82f1\u56fd\uff08\u4f26\u6566\uff09\u7b49\u6d77\u5916\u5e02\u573a\u3002\u5e02\u573a\u73af\u5883\u4e0b\u5229\u6da6\u8981\u6c42\u5c06\u6784\u6210\u538b\u529b\uff08\u524d\u6587\u5df2\u63d0\u5230\u80bf\u7624\u4ea7\u4e1a\u5468\u671f\u662f\u7814\u53d1\u201c\u70e7\u94b1\u201d\u9636\u6bb5\uff09\u3002<\/div>\n
\u00a0<\/div>\n
\u5409\u56e0\u52a0<\/div>\n
2016\u5e74\u5b8c\u62102\u4ebf\u5143A\u8f6e\u878d\u8d44\uff0c\u534e\u5927\u57fa\u56e0\u9886\u6295\u3002\u8f83\u65e9\u5730\u63d0\u51facfDNA\u57fa\u7ebf\u8ba1\u5212\uff0c\u5728\u6570\u636e\u5e93\u65b9\u9762\u53d1\u529b\u8f83\u5927\u3002\u5206\u522b\u5728\u5317\u4eac\u3001\u6df1\u5733\u3001\u82cf\u5dde\u8bbe\u7acb\u8425\u9500\u3001\u6570\u636e\u548c\u7814\u53d1\u7b49\u4e0d\u540c\u56e2\u961f\uff0c\u548c\u534e\u5927\u5408\u4f5c\u8d34\u724c\u6d4b\u5e8f\u4eea\uff0c\u540c\u65f6\u57fa\u4e8eIT\u4f18\u52bf\u7814\u53d1\u80bf\u7624NGS\u5168\u81ea\u52a8\u5206\u6790\u89e3\u8bfb\u4e00\u4f53\u673a\u3002<\/div>\n
\u00a0<\/div>\n
\u6d77\u666e\u6d1b\u65af<\/div>\n
\u6df1\u5733\u5e02\u201c\u5b54\u96c0\u4eba\u624d\u201d\u56e2\u961f\u9879\u76ee\uff0c\u76f8\u5bf9\u4e8e\u5176\u4ed6\u6cdb\u764c\u79cd\u57fa\u56e0\u68c0\u6d4b\u4f01\u4e1a\uff0c\u6bd4\u8f83\u96c6\u4e2d\u4e8e\u80ba\u764c\u548c\u809d\u764c\u7b49\u764c\u79cd\u7684\u65e9\u7b5b\u3002\u8425\u9500\u80fd\u529b\u8f83\u5f3a\u3002\u540c\u65f6\u8fd1\u671f\u4e5f\u5e03\u5c40\u6295\u5165\u6d88\u8d39\u7ea7\u57fa\u56e0\u68c0\u6d4b\u3002<\/div>\n
\u00a0<\/div>\n
\u57fa\u51c6\u533b\u7597<\/div>\n
\u7740\u773c\u4e8e\u4e34\u5e8a\u764c\u75c7\u65e9\u8bca\u3002\u76ee\u524d\u5f00\u5c55\u5305\u62ec\u80ba\u7ed3\u8282\u7b49\u764c\u79cd\u5728\u5185\u7684\u5927\u578b\u4e34\u5e8a\u8bd5\u9a8c\u3002\u521b\u59cb\u4eba\u8303\u5efa\u5175\u6559\u6388\u79d1\u5b66\u51fa\u8eab\uff0c\u54e5\u4f26\u6bd4\u4e9a\u5927\u5b66\u4eba\u7c7b\u9057\u4f20\u5b66\u535a\u58eb\u3001\u201c\u56fd\u5bb6\u5343\u4eba\u201d\uff0c\u66fe\u4efbIllumina\u603b\u76d1\uff0c\u5bb6\u4e61\u4e3a\u6c5f\u53f3\u53e4\u90e1\u3001\u738b\u5b89\u77f3\u7684\u6545\u4e61\u6c5f\u897f\u629a\u5dde\u3002\u9664\u4e86\u5317\u6781\u5149\u3001\u8fdc\u6bc5\u8d44\u672c\u7b49\u8d44\u672c\uff0c\u4e5f\u63a5\u53d7\u4e86\u836f\u660e\u5eb7\u5fb7\u548c\u91d1\u57df\u533b\u5b66\u7684\u6295\u8d44\u3002<\/div>\n
\u00a0<\/div>\n
\u4f18\u8fc5\u533b\u5b66<\/div>\n
\u4ea7\u54c1\u8bbe\u8ba1\u548c\u8425\u9500\u80fd\u529b\u8f83\u5f3a\u3002\u5728\u65e9\u671f\u7684\u4e3b\u4e1a\u751f\u80b2\u5065\u5eb7\u9886\u57df\uff0c\u8f83\u65e9involve NIPT Plus\u4ea7\u54c1\uff1b\u800c\u5728\u80bf\u7624\u7cbe\u51c6\u533b\u7597\u9886\u57df\uff0c\u62e5\u6709ctDNA \u548c CTC \u53cc\u5e73\u53f0\u3002\u5728\u8d44\u6e90\u4e0a\u83b7\u5f97\u534e\u5927\u57fa\u56e0\u7684\u6218\u7565\u5165\u8d44\u3002<\/div>\n
\u00a0<\/div>\n
\u601d\u52e4\u533b\u7597<\/div>\n
\u4e13\u6ce8\u4e8e\u80bf\u7624\u65e9\u7b5b\u3002\u521b\u59cb\u4eba\u7684\u836f\u5382+\u534e\u5927\u57fa\u56e0CSO+\u836f\u660e\u5eb7\u5fb7EVP\u7684\u80cc\u666f\u6210\u4e3a\u878d\u8d44\u540d\u7247\u3002\u63a5\u53d7\u677e\u79be\u8d44\u672c\u5343\u4e07\u7ea7\u5929\u4f7f\u6295\u8d44\u3002\u521b\u7acb\u4e00\u5e74\u5df2\u63a8\u51fa\u764c\u75c7\u65e9\u7b5b\u4ea7\u54c1\u3002<\/div>\n
\u00a0<\/div>\n
\u9e4d\u8fdc\u57fa\u56e0<\/div>\n
\u521b\u59cb\u4eba\u9ad8\u8fdc\u6559\u6388\u548c\u5f20\u9e4d\u6559\u6388\u662f\u57fa\u56e0\u754c\u6cf0\u6597\u4e4b\u4e00George Church\u6559\u6388\u7684\u5b66\u751f\u3002\u5728\u764c\u75c7\u65b9\u9762\u5dee\u5f02\u5316\u7814\u53d1\u7532\u57fa\u5316\u76f8\u5173\u4ea7\u54c1\u3002<\/div>\n
\u00a0<\/div>\n
\u81fb\u548c\u79d1\u6280<\/div>\n
\u5f15\u8fdb\u4e86\u56fd\u5916\u591a\u79cd\u80bf\u7624\u68c0\u6d4b\u4ea7\u54c1\uff0c\u6210\u4e3aMammaPrint\u7b49\u4ea7\u54c1\u5728\u4e2d\u56fd\u7684\u72ec\u5bb6\u6837\u672c\u68c0\u6d4b\u65b9\u548c\u7ecf\u9500\u5546\u3002\u8f83\u4e3a\u4e0d\u540c\u7684\u662f\uff0c\u81fb\u548c\u79d1\u6280\u7684\u80bf\u7624\u4e13\u79d1\u95e8\u8bca\u5df2\u843d\u6237\u65e0\u9521\uff0c\u201c\u672a\u6765\u5c06\u901a\u8fc7MDT\uff08\u4e34\u5e8a\u591a\u5b66\u79d1\u4f1a\u8bca\uff09\u8d70\u5411\u8bca\u7597\u4e00\u4f53\u5316\u201d\u3002<\/div>\n
\u00a0<\/div>\n
\u4ec1\u4e1c\u533b\u5b66<\/div>\n
\u8425\u9500\u80fd\u529b\u8f83\u5f3a\u3002\u6765\u81ea\u539f\u8a89\u8861\u836f\u4e1a\u548c\u534e\u5927\u57fa\u56e0\u9ad8\u7ba1\u7ec4\u6210\u7684\u6838\u5fc3\u56e2\u961f\u3002\u4e13\u6ce8\u5934\u9888\u764c\/\u6ccc\u5c3f\u7cfb\u7edf\u80bf\u7624\/\u809d\u80c6\u80bf\u7624\u7b49\u764c\u79cd\u9886\u57df\u7684\u514d\u75ab\u8bca\u7597\uff0c2018\u5e74\u5b8c\u62107500\u4e07\u4eba\u6c11\u5e01A\u8f6e\u878d\u8d44\uff0c\u7531\u836f\u660e\u5eb7\u5fb7\u65d7\u4e0b\u8d44\u672c\u9886\u6295\u3002<\/div>\n
\u00a0<\/div>\n
\u6c42\u81fb\u533b\u5b66<\/div>\n
\u5e03\u5c40\u764c\u75c7\u5927Panel\uff0c\u8d44\u6e90\u62d3\u5c55\u80fd\u529b\u8f83\u5f3a\u3002\u56fd\u5bb6\u5065\u5eb7\u533b\u7597\u5927\u6570\u636e\u4e2d\u5fc3\u6210\u5458\u5355\u4f4d\u3002<\/div>\n
\u00a0<\/div>\n
\u88d5\u7b56\u751f\u7269<\/div>\n
\u5dee\u5f02\u5316\u80bf\u7624\u514d\u75ab\u3001\u5c24\u5176\u662f\u65b0\u6297\u539f\u9886\u57df\uff0c\u672a\u6765\u4e0e\u836f\u5382\u5408\u4f5c\u53ef\u80fd\u6027\u8f83\u5927\u3002\u83b7\u5f97IDG\u9886\u6295\u7684B\u8f6e\u878d\u8d44\u603b\u8ba12\u4ebf\u4eba\u6c11\u5e01\u3002<\/div>\n
\u00a0<\/div>\n
\u548c\u745e\u57fa\u56e0<\/div>\n
\u8d1d\u745e\u57fa\u56e0\uff08SZ.000710)\u65d7\u4e0b\u5b50\u516c\u53f8\uff0c\u6295\u8d44\u516c\u53f8\u541b\u8054\u8d44\u672c\u53c2\u4e0e\u8fd0\u8425\u3002\u76ee\u524d\u4e3b\u8981\u96c6\u4e2d\u809d\u764c\uff0c2018\u5e74\u6295\u51651\u4ebf\u5143\u5e76\u8054\u5408\u56fd\u5bb6\u809d\u764c\u79d1\u5b66\u4e2d\u5fc3\u53d1\u8d77\u524d\u77bb\u6027\u4e07\u4eba\u961f\u5217\u9879\u76ee\u3002<\/div>\n
\u00a0<\/div>\n
\u5b89\u53ef\u6d4e<\/div>\n
\u6210\u7acb\u4e8e\u7845\u8c37\uff0c\u5728\u4e0a\u6d77\u3001\u82cf\u5dde\u8bbe\u7acb\u4e86\u5206\u516c\u53f8\u548c\u7b2c\u4e09\u65b9\u4e34\u68c0\u4e2d\u5fc3\uff0c\u4e13\u6ce8\u4e8ectDNA-NGS\u6280\u672f\u3002<\/div>\n
\u00a0<\/div>\n
\u5e1d\u57fa\u751f\u7269<\/div>\n
\u603b\u90e8\u8bbe\u7acb\u5728\u7f8e\u56fd\u52a0\u5dde\uff0c\u5728\u5357\u4eac\u3001\u4e0a\u6d77\u3001\u676d\u5dde\u548c\u5929\u6d25\u8bbe\u7acb\u4e86\u5206\u516c\u53f8\u548c\u7b2c\u4e09\u65b9\u4e34\u68c0\u4e2d\u5fc3\u30022018\u5e74\u6536\u8d2d\u9996\u5ea6\u57fa\u56e0\u3002<\/div>\n
\u2026\u2026<\/div>\n
\uff08\u66f4\u591a\u4f01\u4e1a\u65e0\u6cd5\u5b8c\u5168\u5217\u4e3e\uff0c\u66f4\u591a\u4f01\u4e1a\u7ec6\u8282\uff0c\u5305\u62ec\u6838\u5fc3\u4ea7\u54c1\u3001\u5dee\u5f02\u5316\u53ca\u5e02\u573a\u7ade\u4e89\u529b\u7b49\u4fe1\u606f\u8bf7\u53c2\u8003\u300a2019\u5e74\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u884c\u4e1a\u62a5\u544a\u300b\uff0c\u4e5f\u6b22\u8fce\u4f01\u4e1a\u79ef\u6781\u4e0e\u6211\u4eec\u4e92\u4e92\u52a8\u4ea4\u6d41\u53ca\u5408\u4f5c\uff1a\u5fae\u4fe1 jiyinhui_1\uff09<\/div>\n
\u00a0<\/div>\n
\u8fd9\u91cc\u9700\u8981\u6ce8\u610f\u7684\uff0c\u867d\u7136\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u53ca\u6db2\u4f53\u6d3b\u68c0\u9886\u57df\u5728\u56fd\u5185\u4e00\u76f4\u53d7\u5230\u653f\u5e9c\u548c\u8d44\u672c\u7684\u9752\u7750\uff0c\u5728\u9876\u7ea7\u7684\u56fd\u9645\u80bf\u7624\u5b66\u5927\u4f1a\uff0c\u65e0\u8bba\u662f\u4eca\u5e74\u7684AACR \u8fd8\u662fASCO\uff0c\u6765\u81ea\u4e8e\u4e2d\u56fd\u7684\u58f0\u97f3\uff0c\u4e0d\u7ba1\u662f\u5de5\u4e1a\u754c\u8fd8\u662f\u5b66\u672f\u754c\uff0c\u4ecd\u7136\u4ec5\u4ee5\u6d77\u62a5\u65b9\u5f0f\u5c55\u793a\uff0c\u53e3\u5934\u62a5\u544a\u51e0\u4e4e\u6ca1\u6709\uff08\u90e8\u5206\u5728AACR\u5c55\u793a\u7684\u4e2d\u56fd\u764c\u75c7\u7814\u7a76\u6210\u679c\u8bf7\u53c2\u8003\u57fa\u56e0\u6167\u6587\u7ae0\uff1a\u5168\u7403\u6700\u5927\u7684\u764c\u75c7\u7814\u7a76\u5e74\u4f1aAACR\u8981\u70b9\u53ca\u4e2d\u56fd\u58f0\u97f3<\/a>\uff09\u5728\u5b66\u672f\u6210\u679c\u548c\u4ea7\u4e1a\u8f6c\u5316\u4e0a\uff0c\u6211\u4eec\u4ecd\u5b58\u5728\u8ddd\u79bb\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0 \u56db\u00a0\u00a0\u00a0\u00a0\u80bf\u7624\u6db2\u4f53\u6d3b\u68c0\u6210\u719f\u843d\u5730\u4e34\u5e8a\u8fd8\u6709\u591a\u8fdc\uff1f<\/div>\n
\u80bf\u7624\u6db2\u4f53\u6d3b\u68c0\u5728\u4ea7\u4e1a\u5982\u706b\u5982\u837c\uff0c\u5728\u4e34\u5e8a\u7684\u5e94\u7528\u5904\u4e8e\u4e00\u4e2a\u79d1\u7814\u63a2\u7d22\u65f6\u671f\uff0c\u4f46\u6b63\u52a0\u901f\u653f\u7b56\u5ba1\u6279\u548c\u6d41\u7a0b\u843d\u5730\u3002<\/div>\n
\u00a0<\/div>\n
\u4ece\u4e34\u5e8a\u89d2\u5ea6\uff0c\u5b9e\u9a8c\u5ba4\u5e38\u7528\u7684ctDNA\u68c0\u6d4b\u6280\u672f\u5305\u62ec\uff1a\u6269\u589e\u53d7\u963b\u7a81\u53d8\u4f53\u7cfb(amplification refractorymutation system\uff0cARMS)\u3001\u65b0\u4e00\u4ee3\u6d4b\u5e8f(next\uff0dgeneration sequencing\uff0cNGS)\u3001\u6570\u5b57PCR(digital PCR\uff0cdPCR)\u548c\u6838\u9178\u8d28\u8c31\u68c0\u6d4b\u7b49\u6280\u672f\u3002\u5176\u4e2dARMS\u548c\u6280\u672f\u5728\u653f\u7b56\u5ba1\u6279\u65b9\u9762\u8d77\u6b65\u8f83\u65e9\uff0cNGS\u56e0\u4e3a\u901a\u91cf\u4f18\u52bf\u6b63\u52a0\u901f\u5360\u636e\u5e02\u573a\u4efd\u989d\uff0cdPCR\u548c\u8d28\u8c31\u6280\u672f\u5728\u5df2\u77e5\u57fa\u56e0\u7a81\u53d8\u68c0\u6d4b\u65b9\u9762\u8f83\u6709\u4f18\u52bf\u3002<\/div>\n
\u00a0<\/div>\n
\u80bf\u7624\u6db2\u4f53\u6d3b\u68c0\u5728\u4e34\u5e8a\u5e94\u7528\u7684\u9886\u57df\uff0c\u5b98\u65b9\u8ba4\u53ef\u7684\u5305\u62ec\uff1a\u80bf\u7624\u65e9\u671f\u8f85\u52a9\u8bca\u65ad\u3001\u7528\u836f\u6307\u5bfc\u3001\u9776\u5411\u836f\u7269\u4f34\u968f\u8bca\u65ad\u3001\u5b9e\u65f6\u7597\u6548\u76d1\u6d4b\u548c\u8010\u836f\u673a\u5236\u7814\u7a76\u7b49\u3002\u76ee\u524d\u7528\u836f\u6307\u5bfc\u662f\u7b2c\u4e00\u5927\u5e94\u7528\u573a\u666f\uff0c\u9884\u8ba1\u5728\u4e0d\u4e45\u7684\u5c06\u6765\uff0c\u590d\u53d1\u76d1\u6d4b\u5c06\u662f\u7b2c\u4e8c\u5927\u7684\u5e94\u7528\u573a\u666f\uff0c\u653f\u7b56\u6279\u51c6\u5728\u8fd9\u65b9\u9762\u4f1a\u6709\u503e\u659c\uff0c\u800c\u4e14\u53ef\u80fd\u66f4\u503e\u5411\u4e8e\u5927Panel\u3002<\/div>\n
\u00a0<\/div>\n
\u6db2\u4f53\u6d3b\u68c0\u5728\u4e34\u5e8a\u5e94\u7528\u65b9\u9762\u4e5f\u5b58\u5728\u5f88\u5927\u5c40\u9650\u548c\u63a2\u7d22\u6027\u7684\u95ee\u9898\uff1a<\/div>\n
1\uff09\u53ef\u9009\u7684\u764c\u79cdpanel\u548c\u8ba4\u8bc1\u5382\u5546\u6709\u9650<\/div>\n
2\uff09\u6025\u9700\u5efa\u7acb\u516c\u8ba4\u7684\u8d28\u91cf\u6807\u51c6\u4f53\u7cfb<\/div>\n
3\uff09\u5305\u62ec\u652f\u4ed8\u3001\u9057\u4f20\u54a8\u8be2\u3001\u4ee5\u53ca\u4ef7\u503c\u94fe\u6761\u6574\u4f53\u7684\u7ba1\u7406\u6d41\u7a0b\u95ee\u9898<\/div>\n
4\uff09\u5305\u62ec\u5bf9\u4e8eLDT\u670d\u52a1\u7c7b\u548c\u68c0\u6d4b\u8bd5\u5242\u76d2\u4ea7\u54c1\u7c7b\u3001\u7b2c\u4e09\u65b9\u68c0\u9a8c\u516c\u53f8\u4e0e\u533b\u9662\u68c0\u9a8c\u5b9e\u9a8c\u5ba4\u3001\u9001\u68c0\u9a8c\u79d1\u8fd8\u662f\u5168\u6d41\u7a0b\u7b49\u4e0d\u540c\u6a21\u5f0f\u7684\u63a2\u7d22\u3002<\/div>\n
\u00a0<\/div>\n
2016\u5e74\uff0cCSCO\u4e0eCAGC\u8054\u5408\u5728\u300a\u5faa\u8bc1\u533b\u5b66\u6742\u5fd7\u300b\u4e0a\u53d1\u5e03\u4e86\u201c\u6db2\u4f53\u6d3b\u68c0:\u89c4\u8303\u4e0e\u7cbe\u51c6\u540c\u884c\u201d\u7684\u4e34\u5e8a\u6307\u5f15\u4e0e\u5171\u8bc6\uff08\u5171\u8bc6\u89e3\u8bfb\u89c1\u6587\u672b\u53c2\u8003\u6587\u7ae0\uff09\u3002\u201c\u5927\u90e8\u5206\u7684\u5171\u8bc6\u7ea7\u522b\u90fd\u662f2A\uff0c\u5373’\u57fa\u4e8e\u4f4e\u6c34\u5e73\u8bc1\u636e\uff0c\u4e13\u5bb6\u7ec4\u6709\u7edf\u4e00\u5171\u8bc6’\u3002\u8fd9\u65e2\u662f\u5f53\u524d\u6db2\u4f53\u6d3b\u68c0\u4e34\u5e8a\u5e94\u7528\u6210\u719f\u5ea6\u7684\u73b0\u5b9e\u53cd\u6620\uff0c\u4f46\u4ece\u53e6\u4e00\u4e2a\u65b9\u9762\u4e5f\u53ef\u4ee5\u770b\u5230\u4e1a\u754c\u5bf9\u8fd9\u4e2a\u65b9\u5411\u7684\u4e50\u89c2\u5c55\u671b\u3002”<\/div>\n
\u00a0<\/div>\n
2018\u5e74\uff0c\u4e2d\u534e\u533b\u5b66\u4f1a\u68c0\u9a8c\u533b\u5b66\u5206\u4f1a\u3001\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u5458\u4f1a\u4e34\u5e8a\u68c0\u9a8c\u4e2d\u5fc3\u5171\u540c\u5236\u5b9a\u4e86\u300a\u6db2\u4f53\u6d3b\u68c0\u5728\u4e34\u5e8a\u80bf\u7624\u8bca\u7597\u5e94\u7528\u548c\u533b\u5b66\u68c0\u9a8c\u5b9e\u8df5\u4e2d\u7684\u4e13\u5bb6\u5171\u8bc6\u300b\uff08\u5171\u8bc6\u5168\u6587<\/a>\uff09\u660e\u786e\u63d0\u51fa:<\/div>\n
1\uff09\u63a8\u8350\u6db2\u4f53\u6d3b\u68c0\u5e94\u7528\u4e8e\u65e0\u6cd5\u83b7\u53d6\u7ec4\u7ec7\u6807\u672c\u7684\u60a3\u8005<\/div>\n
2\uff09\u9664\u4e86\u6307\u5bfc\u80ba\u764cEGFR\u9776\u5411\u836f\u7269\u9009\u62e9\u4e0e\u4f34\u968f\u8bca\u65ad\u5916\uff0cctDNA\u5728\u7597\u6548\u76d1\u6d4b\u3001\u65e9\u671f\u8f85\u52a9\u8bca\u65ad\u53ca\u80bf\u7624\u8fdb\u5c55\u4e0e\u4e0d\u826f\u9884\u540e\u65e9\u671f\u9884\u8b66\u65b9\u9762\u73b0\u9636\u6bb5\u4ec5\u9650\u4e8e\u79d1\u7814\u63a2\u7d22<\/div>\n
3\uff09 \u7c7b\u4f3c\u7684\uff0c\u9664\u4e86\u8f6c\u79fb\u6027\u7ed3\u76f4\u80a0\u764c\u3001\u4e73\u817a\u764c\u4e0e\u524d\u5217\u817a\u764c\u7684\u8fdb\u5c55\/\u4e0d\u826f\u9884\u540e\u65e9\u671f\u9884\u8b66\u5916\uff0cCTC\u5728\u6307\u5bfc\u7528\u836f\u3001\u7597\u6548\u76d1\u6d4b\u3001\u9776\u5411\u836f\u7269\u4f34\u968f\u8bca\u65ad\u53ca\u65e9\u671f\u8f85\u52a9\u8bca\u65ad\u7b49\u65b9\u9762\u73b0\u9636\u6bb5\u4ec5\u9650\u4e8e\u79d1\u7814\u63a2\u7d22\u3002<\/div>\n
\u00a0<\/div>\n
2018\u5e7410\u6708\uff0c\u7f8e\u56fd\u5bbe\u5915\u6cd5\u5c3c\u4e9a\u5927\u5b66Abramson\u764c\u75c7\u4e2d\u5fc3\u56e2\u961f\u5728\u77e5\u540d\u80bf\u7624\u671f\u520a\u300aJAMA Oncology\u300b\u4e0a\u53d1\u5e03\u7684\u4e00\u9879\u524d\u77bb\u6027\u7814\u7a76\u6307\u51fa\uff0c\u5bf92016\u5e744\u6708\u81f32018\u5e741\u6708\u671f\u95f4323\u4f8b\u60a3\u8005\u4e2d\u63a5\u53d7\u6db2\u4f53\u6d3b\u68c0\u7684195\u4f8b\uff0c\u670990\u4f8b\uff0846%\uff09\u68c0\u6d4b\u51fa\u4e86\u4e34\u5e8a\u76f8\u5173\u7684\u7a81\u53d8\uff0c\u53ef\u9776\u5411\u6cbb\u7597\u7684\u7a81\u53d8\u670958\u4f8b\uff0830%\uff09\u60a3\u8005\u3002\u6587\u7ae0\u63d0\u51fa\u57fa\u4e8e\u8840\u6db2\u7684\u57fa\u56e0\u5206\u578b\u68c0\u6d4b\u5e94\u7eb3\u5165\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u7684\u4e34\u5e8a\u5e38\u89c4\u7ba1\u7406\u4e2d\u3002<\/div>\n
\u00a0<\/div>\n
\u6d77\u519b\u519b\u533b\u5927\u5b66\uff08\u7b2c\u4e8c\u519b\u533b\u5927\u5b66\uff09\u9644\u5c5e\u957f\u6d77\u533b\u9662\u7684\u4efb\u5584\u6210\u6559\u6388\uff08\u8be6\u60c5<\/a>\uff09\u63a5\u53d7\u57fa\u56e0\u6167\u91c7\u8bbf\u65f6\u66fe\u8bf4\u9053\uff1a\u201d\u6211\u66f4\u770b\u597d\u7684\u662f\u628a\u57fa\u56e0\u7684\u6539\u53d8(Alterations)\u4f5c\u4e3a\u4e00\u4e2abiomarker\u6765\u9884\u6d4b\u836f\u7269\u7684\u6cbb\u7597\u6548\u679c\uff0c\u5bf9\u4e8e\u533b\u751f\u548c\u75c5\u4eba\u800c\u8a00\uff0c\u7597\u6548\u662f\u5173\u952e\u3002\u201d<\/div>\n
\u00a0<\/div>\n
\u5409\u6797\u5927\u5b66\u7b2c\u4e00\u533b\u9662\u57fa\u56e0\u8bca\u65ad\u4e2d\u5fc3\u4e3b\u4efb\u59dc\u8273\u82b3\u6559\u6388\uff08\u8be6\u60c5<\/a>\uff09\u63a5\u53d7\u57fa\u56e0\u6167\u91c7\u8bbf\u65f6\u66fe\u63d0\u51fa\uff0c\u6db2\u4f53\u6d3b\u68c0\u662f\u672a\u6765\u4e34\u5e8a\u68c0\u6d4b\u7684\u53d1\u5c55\u8d8b\u52bf\uff0c\u867d\u7136\u76ee\u524d\u5728\u7075\u654f\u5ea6\u4e0a\u5b58\u5728\u4e00\u5b9a\u4e0d\u8db3\uff0c\u4f46\u76f8\u4fe1\u968f\u7740\u6280\u672f\u7684\u8fdb\u6b65\u8fd9\u4e9b\u95ee\u9898\u5c06\u5f97\u5230\u89e3\u51b3\u3002\u57fa\u56e0\u68c0\u6d4b\u6280\u672f\u5fc5\u987b\u5feb\u901f\u53d1\u5c55\u624d\u80fd\u8ddf\u4e0a\u65e5\u76ca\u589e\u957f\u7684\u4e34\u5e8a\u9700\u6c42\uff0c\u89c9\u5f97\u672a\u6765\u6db2\u4f53\u6d3b\u68c0\u4e00\u5b9a\u4f1a\u5927\u653e\u5f02\u5f69\u3002<\/div>\n
\uff08\u66f4\u591a\u4e34\u5e8a\u7684\u9700\u6c42\u53cd\u9988\uff0c\u6b22\u8fce\u4e34\u5e8a\u533b\u751f\u5728\u6587\u7ae0\u4e0b\u65b9\u7559\u8a00\u6216email\u6211\u4eec\u3002\u66f4\u591a\u7684\u4e34\u5e8a\u9700\u6c42\u8c03\u7814\uff0c\u5c06\u4f53\u73b0\u5728\u300a2019\u5e74\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u884c\u4e1a\u62a5\u544a\u300b\u4e2d\uff0c\u656c\u8bf7\u671f\u5f85\u548c\u5408\u4f5c\u3002info@genonet.cn\uff09<\/div>\n
\u00a0<\/div>\n
\u53c2\u8003\u8d44\u6599\uff1a<\/div>\n
1.\u00a0Liquid Biopsy Assay From MSKCC Approved by New York State<\/div>\n
2.\u00a0MSK-ACCESS Receives New York State Approval for New Molecular Assay<\/div>\n
3.\u00a0https:\/\/www.mskcc.org<\/div>\n
4.\u00a0https:\/\/www.mskcc.org\/trending-topics\/msk-access-receives-new-york-state-approval-new-molecular-assay<\/div>\n
5.\u00a0http:\/\/www.guardant360.com\/<\/div>\n
6.\u00a0Clinical Implications of Plasma-Based Genotyping With the Delivery of Personalized Therapy in Metastatic Non\u2013Small Cell Lung Cancer<\/div>\n
7.\u00a0http:\/\/investors.guardanthealth.com\/news-releases\/news-release-details\/guardant-health-reports-fourth-quarter-and-full-year-2018<\/div>\n
8.\u00a0MDxHealth Prostate Cancer Test Gains New York State Approval<\/div>\n
9.\u00a0Clinical Implications of Plasma-Based Genotyping With the Delivery of Personalized Therapy in Metastatic Non\u2013Small Cell Lung Cancer<\/div>\n
\u00a0<\/div>\n
\u3010\u58f0\u660e\u3011\u4ee5\u4e0a\u6587\u7ae0\u4e3a\u57fa\u56e0\u6167\u56e2\u961f\u7f16\u8bd1\u3001\u4e13\u8bbf\u53ca\u5206\u6790\u800c\u539f\u521b\u3002\u6211\u4eec\u529b\u6c42\u5ba2\u89c2\u548c\u4e25\u8c28\uff0c\u4f46\u56e0\u4e3a\u884c\u4e1a\u7279\u70b9\u5b58\u5728\u4e00\u5b9a\u5c40\u9650\uff0c\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u4e0d\u7528\u4e8e\u4e34\u5e8a\u533b\u60a3\u54a8\u8be2\u3002\u7248\u6743\u6240\u6709\uff0c\u673a\u6784\u6216\u76f8\u5173\u516c\u4f17\u53f7\u8f6c\u8f7d\u8bf7\u5728\u6587\u7ae0\u663e\u8457\u4f4d\u7f6e\u6ce8\u660e\u6765\u81ea\u57fa\u56e0\u6167\uff1b\u4e2a\u4eba\u6b22\u8fce\u8f6c\u53d1\u548c\u5206\u4eab\u3002\u66f4\u591a\u8d44\u8baf\u53ca\u9879\u76ee\u62a5\u9053\u53ca\u4ea7\u4e1a\u54a8\u8be2\u6b22\u8fce\u5408\u4f5c\u3002<\/div>\n
\u7f16\u8f91\uff1aCC<\/div>\n
\u6821\u5bf9\uff1aNicole<\/div>\n
\u5ba1\u6838\uff1aMark\u00a0<\/div>\n
\u00a0<\/div>\n
\u00a0\u76f8\u5173\u6587\u7ae0\u00a0<\/div>\n
10\u4f4d\u4e13\u5bb6\u89e3\u8bfb\uff1aFDA\u6279\u51c6MSK-IMPACT<\/a><\/div>\n
FDA\u548cCMS\u6279\u51c6FMI\u591a\u764c\u79cd\u4f34\u968f\u8bca\u65ad<\/a><\/div>\n
\u6570\u4f4d\u57fa\u56e0\u4f01\u4e1a\u521b\u59cb\u4eba\u89e3\u8bfb\u300a\u6db2\u4f53\u6d3b\u68c0\u5171\u8bc6\u300b<\/a><\/div>\n
\u00a0CSCO\u573a\u5916\uff1a\u6db2\u4f53\u6d3b\u68c0\u516c\u53f8\u521b\u59cb\u4eba\u89e3\u8bfb\u5171\u8bc6<\/a><\/div>\n
\u00a0<\/div>\n
\u00a0\u52a0\u5165\u57fa\u56e0\u6167\u56e2\u961f\u00a0<\/div>\n
\u00b7 \u884c\u4e1a\u5206\u6790\u5e08<\/div>\n
\u7ad9\u5728\u5c71\u5934\u5206\u6790\u4ea7\u4e1a\u56fe\u8c31\uff0c\u6df1\u5165\u4e00\u7ebf\u4f5c\u4e1a\u54a8\u8be2<\/div>\n
\u00a0<\/div>\n
\u00b7\u00a0\u65b0\u5a92\u4f53\u7f16\u8f91<\/div>\n
\u4e0e\u5927\u5496\u96f6\u8ddd\u79bb\uff0c\u7ad9\u5728\u884c\u4e1a\u8d44\u8baf\u7b2c\u4e00\u7ebf<\/div>\n
\u00b7\u00a0\u5546\u52a1\u62d3\u5c55<\/div>\n
\u4e0e\u4f01\u4e1a\/\u56ed\u533a\/\u8d44\u672c\/\u8de8\u754c\u673a\u6784\u7b49\u6d3d\u8c08\u5408\u4f5c<\/div>\n
\uff08\u7b80\u5386\u6295\u9012\u90ae\u7bb1\uff1a info@genonet.cn)<\/div>\n
\u00a0<\/div>\n
\u00a0\u53c2\u4e0e\u57fa\u56e0\u6167\u8bfb\u8005\u7fa4\u00a0<\/div>\n
\u6dfb\u52a0Mark\u5fae\u4fe1\u5e76\u8d50\u540d\u7247\uff0c\u7ecf\u5ba1\u6838\u540e\u9080\u8bf7\u8fdb\u7fa4<\/div>\n
\u6dfb\u52a0\u65f6\u8bf7\u52a1\u5fc5\u5907\u6ce8\u771f\u5b9e\u4fe1\u606f\uff1a\u5355\u4f4d-\u804c\u4f4d-\u59d3\u540d<\/div>\n\n
\n![\"640?wx_fmt=jpeg\"\/](\"https:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/RmFicvQBAkgCIniaBVXdZJGhprQkPPCBddQxw0icic5Z3nzQluvyNB7Rpib69K5AfqwTqF0pk2fLHVuroluTUG7Zwicg\/640?wx_fmt=jpeg\")
<\/figure><\/div>\n\n<\/div>\n
<\/div>\n
<\/div>\n
\u3010\u5173\u4e8e\u57fa\u56e0\u6167\u3011\u57fa\u56e0\u6167\u662f\u4e00\u5bb6\u72ec\u7acb\u7684\u57fa\u56e0\u548c\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u521b\u65b0\u670d\u52a1\u673a\u6784\uff0c\u6210\u7acb\u4e8e2016\u5e74\uff0c\u57fa\u4e8e10\u5e74\u884c\u4e1a\u5b9e\u8df5\uff0c\u6211\u4eec\u5efa\u7acb\u4e863000+\u4f01\u4e1a\u5e93\u3001\u667a\u5e93\u548c\u5a92\u4f53\u5e73\u53f0YourMap\uff0c\u63d0\u4f9b\u4ea7\u4e1a\u89c4\u5212\u3001\u54a8\u8be2\u57f9\u8bad\u548c\u79d1\u6280\u4f20\u5a92\u7b49\u670d\u52a1\uff0c\u81f4\u529b\u4e8e\u548c\u5408\u4f5c\u4f19\u4f34\u4e00\u8d77\u5efa\u7acb\u6570\u5b57\u751f\u547d\u5065\u5eb7\u521b\u65b0\u670d\u52a1\u5e73\u53f0\u3002<\/div>\n
<\/div>\n
\u57fa\u56e0\u6167\u662f\u56fd\u5bb6\u53d1\u6539\u59d4\u300a2019\u5e74\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b\u7f16\u59d4\u7684\u5355\u4f4d\u3001\u5168\u56fd\u536b\u751f\u4ea7\u4e1a\u4f01\u4e1a\u7ba1\u7406\u534f\u4f1a\u7cbe\u51c6\u533b\u7597\u5206\u4f1a\u7406\u4e8b\u7684\u5355\u4f4d\u3001\u300a\u4e34\u5e8a\u751f\u7269\u6837\u672c\u5e93\u63a2\u7d22\u4e0e\u5b9e\u8df5<\/a>\u300b\u7684\u7f16\u59d4\u5355\u4f4d\uff0c\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5b66\u4f1a\u653f\u7b56\u7814\u7a76\u5206\u4f1a\u5e38\u59d4\u7684\u5355\u4f4d\u3001\u6df1\u5733\u5e02\u5065\u5eb7\u4ea7\u4e1a\u53d1\u5c55\u4fc3\u8fdb\u4f1a\u526f\u4f1a\u957f\u5355\u4f4d\uff0c\u53d1\u5e03\u4e86\u300a2019 \u5e74\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b<\/a>\u7b49\u884c\u4e1a\u62a5\u544a\uff0c\u53c2\u4e0e\u7ec4\u7ec7\u9996\u4e2a\u300a\u4e34\u5e8a\u57fa\u56e0\u68c0\u6d4b\u62a5\u544a\u89c4\u8303\u4e0e\u57fa\u56e0\u68c0\u6d4b\u884c\u4e1a\u5171\u8bc6\u300b<\/a>\u53ca\u76f8\u5173\u56e2\u4f53\u6807\u51c6\u53d1\u5e03\uff0c\u53c2\u4e0e\u4e3b\u529e\u4e86\u9996\u5c4a\u6570\u5b57\u5065\u5eb7\u79c1\u8463\u4f1a<\/a>\u3001\u9996\u5c4a\u7ca4\u6e2f\u6fb3\u5927\u6e7e\u533a\u751f\u547d\u5065\u5eb7\u521b\u65b0\u8bba\u575b<\/a>\u3001\u7b2c\u4e00\u5c4a<\/a>\u548c\u7b2c\u4e8c\u5c4a\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\u5927\u4f1a<\/a>\uff0c\u670d\u52a1\u6570\u5b57\u751f\u547d\u5065\u5eb7\u521b\u65b0\u53d1\u5c55\u3002<\/div>\n
<\/div>\n
\u6b22\u8fce\u91d1\u878d\u673a\u6784\u3001\u56ed\u533a\u53ca\u8de8\u754c\u673a\u6784\u5408\u4f5c\uff0c\u878d\u5408\u53d1\u5c55\uff0c\u8d4b\u80fd\u6295\u878d\u8d44\u53ca\u4ea7\u4e1a\u7fa4\uff08info@genonet.cn)<\/div>\n
<\/div>\n
<\/div>\n
\n\n
\n![\"RmFicvQBAkgDwDDlibn6LGMERd60A1XgibkVTEVrPEb1EoTK1HnjticKMtrzWS4eyuZgibs4H2ErBL6cp0GRTKvEAkg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDwDDlibn6LGMERd60A1XgibkVTEVrPEb1EoTK1HnjticKMtrzWS4eyuZgibs4H2ErBL6cp0GRTKvEAkg.jpeg\")
<\/figure><\/div>","protected":false},"excerpt":{"rendered":"
<\/figure><\/div>","protected":false},"excerpt":{"rendered":"\u6db2\u4f53\u6d3b\u68c0\u4ea7\u54c1\u548c\u4f01\u4e1a\u521d\u6b65\u76d8\u70b9<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[1813,1576],"class_list":["post-9250","post","type-post","status-publish","format-standard","hentry","category-industryresearch","tag-msk","tag-1576"],"_links":{"self":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9250","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/comments?post=9250"}],"version-history":[{"count":3,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9250\/revisions"}],"predecessor-version":[{"id":13990,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9250\/revisions\/13990"}],"wp:attachment":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/media?parent=9250"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/categories?post=9250"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/tags?post=9250"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}