{"id":9240,"date":"2019-11-11T12:14:10","date_gmt":"2019-11-11T04:14:10","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100010714&idx=1&sn=420128064f2e76d915b4d57fbd76f120&chksm=6b71586d5c06d17bb990dec94ac5f0044cd3a5c7a3c32a655be6a15114d31323907d64192ec5#rd"},"modified":"2026-04-02T12:25:00","modified_gmt":"2026-04-02T04:25:00","slug":"549856","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2019\/11\/11\/549856\/","title":{"rendered":"GeneMail\u7b80\u62a5\uff1a11\u6708\u9996\u5468\u56de\u987e\uff0c\u653f\u7b56\u3001\u6280\u672f\u4e0e\u5e02\u573a\u5e76\u9a7e\u9f50\u9a71"},"content":{"rendered":"

<\/p>\n

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11\u67085\u65e5\uff0c\u82f1\u56fd\u536b\u751f\u548c\u793e\u4f1a\u4fdd\u969c\u5927\u81e3Matt Hancock\u5728Genomics England\u7ec4\u7ec7\u7684\u4f1a\u8bae\u4e0a\u8868\u793a\u82f1\u56fd\u8ba1\u5212\u5728\u5c06\u6765\u5bf9\u6240\u6709\u65b0\u751f\u513f\u8fdb\u884c\u57fa\u56e0\u7ec4\u6d4b\u5e8f\uff0c\u4ee5\u68c0\u6d4b\u51fa\u65b0\u751f\u513f\u7684\u9057\u4f20\u75c5\u98ce\u9669\u5e76\u63d0\u4f9b\u53ef\u9884\u6d4b\u7684\u4e2a\u4f53\u5316\u7684\u62a4\u7406\u3002\uff08\u5c39\u54e5\u804a\u57fa\u56e0\uff09<\/div>\n
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\u57289\u6708\u4e8ePLOS ONE\uff08doi\uff1a10.1371 \/ journal.pone.0206484\uff09\u53d1\u8868\u7684\u4e00\u7bc7\u8bba\u6587\u4e2d\uff0c\u4e00\u7ec4\u7814\u7a76\u4eba\u5458\u63cf\u8ff0\u4e86\u4e00\u4e2a\u521d\u59cb\u7684\u57fa\u7ebf\u5065\u5eb7\u80a0\u9053\u5fae\u751f\u7269\u7ec4\u53c2\u8003\u6570\u636e\u5e93\uff0c\u5e76\u63d0\u51fa\u4e86\u4e00\u4e2a\u539f\u578b\u62a5\u544a\u6a21\u677f\u3002\u76ee\u7684\u662f\u7ed8\u5236\u5065\u5eb7\u7684\u80a0\u9053\u5fae\u751f\u7269\u7ec4\u56fe\u8c31\uff0c\u4ee5\u4fbf\u7814\u7a76\u4eba\u5458\u53ef\u4f7f\u7528\u8fd9\u4e9b\u6570\u636e\u6765\u5f00\u53d1\u9488\u5bf9\u75be\u75c5\u7684\u9884\u6d4b\u6a21\u578b\u3002\uff08Bio.IT World\uff09<\/div>\n
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\u753150\u540d\u7814\u7a76\u4eba\u5458\u7ec4\u6210\u7684\u56fd\u9645\u5408\u4f5c\u7ec4\u7ec7\u901a\u8fc7\u7814\u7a76\u5c06\u950c\u8f6c\u8fd0\u86cb\u767d\u5b9a\u4f4d\u4e3a\u6297\u7cd6\u5c3f\u75c5\u6cbb\u7597\u7684\u6709\u5438\u5f15\u529b\u548c\u5b89\u5168\u7684\u76ee\u6807\u3002\u5982\u679c\u80fd\u591f\u5f00\u53d1\u51fa\u6a21\u4effSCL30A8\u57fa\u56e0\u7a81\u53d8\u7684\u4fdd\u62a4\u4f5c\u7528\u7684\u836f\u7269\uff0c\u5219\u53ef\u4ee5\u7ef4\u6301\u03b2\u7ec6\u80de\u529f\u80fd\u5e76\u7ef4\u6301\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u80f0\u5c9b\u7d20\u5206\u6ccc\u80fd\u529b\u3002<\/div>\n
\u00a0<\/div>\n
9.\u300a\u81ea\u7136\u300b\uff1a\u7a7a\u95f4\u6269\u5c55\u751f\u5883\u5b9a\u690d\u7684\u8fdb\u5316\u7a33\u5b9a\u6027\u7b56\u7565<\/div>\n
11 \u6708 7 \u65e5\uff0cNature \u6742\u5fd7\u53d1\u8868\u4e86\u4e2d\u56fd\u79d1\u5b66\u9662\u6df1\u5733\u5148\u8fdb\u6280\u672f\u7814\u7a76\u9662\u3001\u6df1\u5733\u5408\u6210\u751f\u7269\u5b66\u521b\u65b0\u7814\u7a76\u9662\u5218\u9648\u7acb\u7814\u7a76\u5458\u5b9e\u9a8c\u5ba4\u548c\u52a0\u5dde\u5927\u5b66\u5723\u5730\u4e9a\u54e5\u5206\u6821\u534e\u6cf0\u7acb\u6559\u6388\u5b9e\u9a8c\u5ba4\u7684\u5408\u4f5c\u6210\u679c”\u7a7a\u95f4\u6269\u5c55\u751f\u5883\u5b9a\u690d\u7684\u8fdb\u5316\u7a33\u5b9a\u6027\u7b56\u7565”(An evolutionarily stable strategy to colonize spatially extended habitats)\u3002\uff08DeepTech \u6df1\u79d1\u6280\uff09<\/div>\n
\u00a0<\/div>\n
10.\u7b2c\u4e00\u4e2a\u5b8c\u5168\u5408\u6210\u4e14\u5f7b\u5e95\u6539\u53d8DNA\u5bc6\u7801\u7684\u751f\u7269\u8bde\u751f<\/div>\n
5\u670816\u65e5\uff0c\u53d1\u8868\u5728\u300aNature\u300b\u4e0a\u7684\u4e00\u9879\u7814\u7a76\u663e\u793a\uff0c\u82f1\u56fd\u5251\u6865\u5927\u5b66\u7684\u79d1\u5b66\u5bb6\u5df2\u5728\u5b9e\u9a8c\u5ba4\u6210\u529f\u521b\u9020\u4e86\u4e16\u754c\u4e0a\u7b2c\u4e00\u4e2a\u5b8c\u5168\u5408\u6210\u5e76\u4e14\u5f7b\u5e95\u6539\u53d8DNA\u5bc6\u7801\u7684\u751f\u547d\u4f53\u2014\u2014\u5927\u80a0\u6746\u83cc\uff08Escherichia coli\uff09\u3002\u4e0e\u5176\u5929\u7136\u8fd1\u4eb2\u76f8\u4f3c\uff0c\u4f46\u4f9d\u9760\u4e00\u5957\u8f83\u5c0f\u7684\u9057\u4f20\u6307\u4ee4\u5b58\u6d3b\u3002\uff08\u4eca\u65e5\u5934\u6761\uff09<\/div>\n
\u00a0<\/div>\n
\u3010\u5e94\u7528\u62a5\u9053\u3011<\/div>\n
11.\u65b0\u751f\u513f\u7b5b\u67e550\u5e74\uff1a\u4ecePKU\u5230\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f<\/div>\n
Vockley\u535a\u58eb\u6307\u51fa\uff0c\u9700\u8981\u5168\u7403\u6027\u7684\u89e3\u51b3\u65b9\u6848\u6765\u9a8c\u8bc1\u548c\u4f18\u5316\u4e0d\u65ad\u6269\u5c55\u7684\u65b0\u751f\u513f\u7b5b\u67e5\u8ba1\u5212\u3002\u56e0\u4e3a\u5bf9\u533b\u7597\u4fdd\u5065\u7cfb\u7edf\u7684\u603b\u5f00\u652f\u6765\u8bf4\uff0c\u4f7f\u7528\u8fd9\u4e9b\u7597\u6cd5\u901a\u5e38\u6bd4\u652f\u4ed8\u75be\u75c5\u7684\u957f\u671f\u540e\u9057\u75c7\u66f4\u7b26\u5408\u6210\u672c\u6548\u76ca\u3002\uff08\u751f\u7269\u63a2\u7d22-\u89c2\u5bdf\uff09<\/div>\n

12.\u963b\u65ad\u4e73\u817a\u764c\u6216\u5375\u5de2\u764c\u6613\u611f\u57fa\u56e0\u7a81\u53d8\u7684\u201c\u65e0\u764c\u5b9d\u5b9d\u201d\u8bde\u751f10\u670818\u65e5\uff0c\u963b\u65ad\u4e73\u817a\u764c\u6216\u5375\u5de2\u764c\u6613\u611f\u57fa\u56e0\u7a81\u53d8\u7684\u201c\u65e0\u764c\u5b9d\u5b9d\u201d\u68ee\u68ee\uff0c\u5728\u4e2d\u4fe1\u6e58\u96c5\u751f\u6b96\u4e0e\u9057\u4f20\u4e13\u79d1\u533b\u9662\u8bde\u751f\u3002\u5373\u901a\u8fc7\u5148\u8fdb\u7684\u690d\u5165\u524d\u9057\u4f20\u5b66\u8bca\u65ad\u6280\u672f\uff08PGD\uff09\u6392\u9664\u4e86\u5bb6\u65cf\u9057\u4f20\u7684BRCA1\u57fa\u56e0\u7a81\u53d8\u3002\uff08\u4e2d\u4fe1\u533b\u7597\uff09<\/p>\n

13.NMPA IND\u6279\u51c6\u6297\u00a0PD-1\/CD47\u53cc\u7279\u5f02\u6297\u4f53\u65b0\u836fHX009<\/div>\n
10\u670830\u65e5\uff0c\u676d\u5dde\u7ff0\u601d\u751f\u7269\u3001\u6b66\u6c49\u7ff0\u96c4\u751f\u7269\u5ba3\u5e03\uff0cNMPA IND\u5df2\u6279\u51c6\u5176\u5229\u7528\u7ff0\u601d\u72ec\u7279\u53cc\u529f\u80fd\u6297\u4f53\u53ca\u878d\u5408\u86cb\u767d\u5e73\u53f0\u81ea\u4e3b\u7814\u53d1\u7684\u6297 PD-1\/CD47\u53cc\u7279\u5f02\u6297\u4f53\u65b0\u836f HX009\u3002\uff08\u6885\u65af\u533b\u5b66\uff09<\/div>\n
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11\u67086\u65e5\uff0c\u534e\u6da6\u751f\u547d\u79d1\u5b66\u6b63\u5f0f\u63ed\u724c\uff0c\u610f\u5473\u7740\u751f\u547d\u79d1\u5b66\u5df2\u6210\u4e3a\u534e\u6da6\u65b0\u7684\u91cd\u70b9\u53d1\u5c55\u65b9\u5411\u4e4b\u4e00\u3002\u540c\u65e5\uff0c\u4ee5\u201c\u5174\u534e\u6709\u9053 \u878d\u6da6\u4e07\u7269\u201d\u4e3a\u4e3b\u9898\u7684\u9996\u5c4a\u534e\u6da6\u751f\u547d\u79d1\u5b66\u521b\u65b0\u8bba\u575b\u4e5f\u5728\u5317\u4eac\u534e\u6da6\u751f\u547d\u79d1\u5b66\u56ed\u6210\u529f\u4e3e\u529e\u3002\uff08\u534e\u6da6\uff09<\/div>\n
\u00a0<\/div>\n
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11\u67084\u65e5\uff0c\u81f4\u529b\u4e8eAI\u5fae\u751f\u6001\u5236\u836f\u7814\u53d1\u7684\u672a\u77e5\u541b\u751f\u7269\uff0c\u5ba3\u5e03\u5b8c\u6210\u8fc7\u4ebfB\u8f6e\u878d\u8d44\u3002\u541b\u8054\u8d44\u672c\u9886\u6295\uff0c\u539f\u6709\u6295\u8d44\u65b9\u9ad8\u6995\u8d44\u672c\u3001\u6668\u5174\u8d44\u672c\u3001\u96c5\u60e0\u6295\u8d44\u7ee7\u7eed\u8ddf\u6295\u3002\uff08\u672a\u77e5\u541b\uff09<\/div>\n
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11\u67084\u65e5\uff0c\u81f4\u529b\u4e8e\u5f00\u53d1\u5e94\u7528\u5355\u7ec6\u80de\u5168\u57fa\u56e0\u7ec4\u7b49\u6280\u672f\uff0c\u4ea7\u4e1a\u5316\u5e94\u7528\u4e8e\u9057\u4f20\u75c5\u7684\u5b55\u524d\u7cbe\u51c6\u9632\u63a7\u7b49\u9886\u57df\u7684\u4ebf\u5eb7\u57fa\u56e0\uff0c\u5ba3\u5e03\u5b8c\u6210\u4ebf\u5143\u7ea7A+\u8f6e\u878d\u8d44\uff0c\u91d1\u9616\u8d44\u672c\uff08\u91d1\u57df\u533b\u5b66\u5173\u8054\u57fa\u91d1\uff09\u9886\u6295\uff0c\u8d8a\u79c0\u4ea7\u4e1a\u57fa\u91d1\u3001\u4e2d\u5143\u4e5d\u6d3e\u57fa\u91d1\u3001\u4ea4\u94f6\u79d1\u521b\u80a1\u6743\u6295\u8d44\u57fa\u91d1\u7b49\u8ddf\u6295\u3002\uff08\u6d4b\u5e8f\u4e2d\u56fd\uff09<\/div>\n
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10\u670831\u65e5\uff0c\u805a\u7126\u4e8e\u80bf\u7624\u5316\u7597\u540e\u83cc\u7fa4\u91cd\u5efa\u3001\u7cd6\u5c3f\u75c5\u7b49\u4ee3\u8c22\u7c7b\u75be\u75c5\u7684\u83cc\u7fa4\u5173\u8054\u7814\u7a76\uff0c\u4ee5\u53ca\u57fa\u56e0\u4fee\u9970\u7684\u80a0\u9053\u5fae\u751f\u7269\u7814\u7a76\u7684\u4e00\u516e\u751f\u7269\uff0c\u5ba3\u5e03\u5b8c\u6210\u5343\u4e07\u5143\u5929\u4f7f\u8f6e\u878d\u8d44\u3002\uff0836 \u6c2a APP\uff09<\/div>\n

18.\u5e7f\u5dde\u627f\u845b\u751f\u7269\uff0c\u5b8c\u6210\u6570\u5343\u4e07\u5143\u5929\u4f7f\u8f6e\u548cPre-A\u8f6e\u878d\u8d44<\/p>\n

\u8fd1\u65e5\uff0c\u4e2d\u56fd\u9996\u5bb6\u63d0\u4f9b\u7cbe\u51c6\u5316\u83cc\u7fa4\u79fb\u690d\u6cbb\u7597\u6574\u4f53\u89e3\u51b3\u65b9\u6848\u7684\u627f\u845b\u751f\u7269\uff0c\u5ba3\u5e03\u5b8c\u6210\u6570\u5343\u4e07\u5143\u5929\u4f7f\u8f6e\u548cPre-A\u8f6e\u878d\u8d44\u3002\u5929\u4f7f\u8f6e\u878d\u8d44\u5e7f\u5dde\u547c\u7814\u6240\u533b\u836f\u79d1\u6280\u6709\u9650\u516c\u53f8\u9886\u6295\uff0c\u9633\u666e\u6e7e\u521b\u65b0\u4f01\u4e1a\u5b75\u5316\u5668\u8ddf\u6295\uff1bPreA\u8f6e\u878d\u8d44\u7531\u4e09\u6cfd\u521b\u6295\u9886\u6295\uff0c\u5e7f\u534e\u521b\u6295\u8ddf\u6295\uff0c\u73b0\u5df2\u5b8c\u6210\u4ea4\u5272\u3002\uff08\u52a8\u8109\u7f51\uff09<\/p>\n

19.\u4e91\u950b\u57fa\u91d1\u4e5d\u5e74\u9996\u6b21\u62ab\u9732\u6218\u7ee9 \u9a6c\u4e91\u95ed\u95e8\u5bf9\u8bdd\u865e\u950b\u5b9e\u5f5511\u67086\u65e5\uff0c 2019\u4e91\u950b\u57fa\u91d1\u5168\u7403\u6295\u8d44\u8005\u5927\u4f1a\u5728\u6df1\u5733\u4e3e\u884c\u3002\u8fd9\u5bb6\u5e73\u65e5\u9887\u4e3a\u4f4e\u8c03\u7684\u6295\u8d44\u673a\u6784\uff0c\u9762\u5411\u6295\u8d44\u4eba\u4eae\u51fa\u4e86\u6210\u7ee9\u5355\uff1a\u57fa\u91d1\u6210\u7acb9\u5e74\u6765\uff0c\u8d44\u91d1\u7ba1\u7406\u89c4\u6a21\u6210\u957f60\u591a\u500d\uff0c\u57fa\u91d1\u5e73\u5747\u5e74\u56de\u62a5\u7387\uff08IRR\uff09\u9ad8\u8fbe30%\u3002\uff08\u6295\u8d44\u754c\uff09<\/p>\n

\u00a0\u62d3\u5c55\u9605\u8bfb\u00a0<\/p>\n

\u82f1\u56fd10\u4e07\u4eba\u57fa\u56e0\u7ec4\u8ba1\u5212<\/a><\/p>\n

\u5341\u5e74\u540e\u6700\u8d35\u7684\u5962\u4f88\u54c1<\/a><\/div>\n
\u00a0\u52a0\u5165\u8bfb\u8005\u7fa4\/\u5408\u4f5c\u00a0<\/div>\n
\u6dfb\u52a0\u5fae\u4fe1 jiyinhui_1\uff08\u53e3\u4ee4\uff1a\u5355\u4f4d-\u804c\u4f4d-\u59d3\u540d\uff09<\/div>\n
\uff08\u901a\u8fc7\u540e\u8bf7\u8d50\u540d\u7247\uff09<\/div>\n\n
\n
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\u57fa\u56e0\u548c\u6570\u5b57\u751f\u547d\u5065\u5eb7\u884c\u4e1a\u7b80\u62a5<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"close","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[996],"tags":[1778,1544,2156],"class_list":["post-9240","post","type-post","status-publish","format-standard","hentry","category-news","tag-1778","tag-1544","tag-2156"],"_links":{"self":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9240","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/comments?post=9240"}],"version-history":[{"count":4,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9240\/revisions"}],"predecessor-version":[{"id":13900,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9240\/revisions\/13900"}],"wp:attachment":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/media?parent=9240"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/categories?post=9240"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/tags?post=9240"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}