{"id":9239,"date":"2019-07-21T21:55:55","date_gmt":"2019-07-21T13:55:55","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&#038;mid=100010723&#038;idx=1&#038;sn=4df3705180161d5fb7843241fd1c2307&#038;chksm=6b7158545c06d142cdd841ec4cad2bf3366cfd7c5baa4ef6bcd229147d9757d2b3948243c0c5#rd"},"modified":"2026-03-19T19:12:04","modified_gmt":"2026-03-19T11:12:04","slug":"9710197","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2019\/07\/21\/9710197\/","title":{"rendered":"GeneMail\u7b80\u62a5\uff1a\u200b\u6ce2\u58eb\u987f\u513f\u7ae5\u533b\u9662\u7814\u53d1\u731d\u6b7b\u57fa\u56e0\u6cbb\u7597\uff0c\u5317\u5927\u53d1\u8868RNA\u5355\u78b1\u57fa\u7f16\u8f91\u6280\u672f"},"content":{"rendered":"<p><!-- wechat_content_hash: aeaa315ddfa8a2b1 --><\/p>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg.gif\" alt=\"RmFicvQBAkgCuC54K47siaoibvbClYbpoQdmoEA7Yo9T0l4l5c9wsK8DWv13zXvBYojNDUX4HpbxOEe8enSicCuVVg\"\/><\/figure><\/div>\n\n<div>\u301079\u671f\u770b\u70b9\u3011\u521b\u65b0RNAi\u7597\u6cd5\u83b7FDA\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0cAveXis\u548cParagon\u5408\u4f5cSMA\u57fa\u56e0\u6cbb\u7597\uff0c\u6fc0\u5149\u62a4\u80a4\u7684\u5173\u952e\u4f5c\u7528\u56e0\u5b50\u53ef\u80fd\u662fdsRNA\uff0c\u201c\u9057\u4f20\u4e0e\u4eba\u7c7b\u5065\u5eb7\u201d\u9662\u58eb\u8bba\u575b\u5c06\u57288\u6708\u8d35\u9633\u53ec\u5f00\u3002<\/div>\n<div>* 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class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/mmbiz.qpic.cn\/mmbiz_png\/RmFicvQBAkgBfrZrZ5wZnkCibaVkITHfaLaP4gibM5g2WHRFmnQSpQGZnqbOU9o4vESoibRBZxa44AdPibtETfPVCIg\/640?wx_fmt=png\" 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Biotechnology\u6742\u5fd7\u5728\u7ebf\u53d1\u8868\u4e86\u7814\u7a76\u8bba\u6587\uff0c\u9996\u6b21\u62a5\u9053\u4e86\u540d\u4e3aLEAPER\u7684\u65b0\u578bRNA\u5355\u78b1\u57fa\u7f16\u8f91\u6280\u672f\u3002\u5229\u7528\u8be5\u6280\u672f\uff0c\u7814\u7a76\u4eba\u5458\u5728\u4e00\u7cfb\u5217\u75be\u75c5\u76f8\u5173\u57fa\u56e0\u8f6c\u5f55\u672c\u4e2d\u5b9e\u73b0\u4e86\u9ad8\u6548\u3001\u7cbe\u51c6\u7684\u7f16\u8f91\uff0c\u5e76\u6210\u529f\u4fee\u590d\u4e86\u6765\u6e90\u4e8eHurler\u7efc\u5408\u5f81\u75c5\u4eba\u7684\u03b1-L-\u827e\u675c\u7cd6\u919b\u9178\u9176\u7f3a\u9677\u7ec6\u80de\u3002\u8be5\u6280\u672f\u7684\u5efa\u7acb\u4e3a\u751f\u547d\u79d1\u5b66\u57fa\u7840\u7814\u7a76\u548c\u75be\u75c5\u6cbb\u7597\u63d0\u4f9b\u4e86\u4e00\u79cd\u5168\u65b0\u7684\u5de5\u5177\u3002\uff08\u535a\u96c5\u8f91\u56e0\uff09<\/div>\n<div>\u00a0<\/div>\n<div>\u6fc0\u5149\u62a4\u80a4\u7684\u5173\u952e\u4f5c\u7528\u56e0\u5b50\u53ef\u80fd\u662fdsRNA<\/div>\n<div>\u8fd1\u65e5\uff0c\u79d1\u5b66\u5bb6\u4eec\u53d1\u73b0RNA\u7684\u4ea7\u751f\u662f\u6fc0\u5149\u62a4\u80a4\u6cbb\u7597\u518d\u751f\u5f71\u54cd\u7684\u539f\u56e0\u3002\u6fc0\u5149\u4f1a\u8f7b\u5fae\u635f\u4f24\u76ae\u80a4\u7ec6\u80de\uff0c\u8feb\u4f7f\u5b83\u4eec\u81ea\u884c\u4fee\u590d\u3002\u5728\u4fee\u590d\u8fc7\u7a0b\u4e4b\u540e\uff0c\u76ae\u80a4\u770b\u8d77\u6765\u66f4\u5e74\u8f7b\uff0c\u4e3a\u4e86\u7406\u89e3\u8fd9\u4e00\u8fc7\u7a0b\uff0c\u7814\u7a76\u4eba\u5458\u7814\u7a76\u4e86\u5c0f\u9f20\u7684\u6bdb\u56ca\u518d\u751f\u3002\u8001\u9f20\u53ef\u4ee5\u5728\u6df1\u5ea6\u4f24\u53e3\u540e\u518d\u751f\u6bdb\u56ca\u3002\u53d7\u635f\u7ec6\u80de\u91ca\u653e\u81ea\u6211\u7f16\u7801\u7684\u53cc\u94feRNA\u5206\u5b50\uff08dsRNA\uff09\uff0c\u5f00\u59cb\u518d\u751f\u8fc7\u7a0b\u3002<\/div>\n<div>\u00a0<\/div>\n<div>1000\u4e07\u6d3b\u4ea7\u5a74\u513f\u6570\u636e\u8bc4\u4f30\u51fa\u751f\u7f3a\u9677\u4e0e\u513f\u7ae5\u671f\u764c\u75c7\u76f8\u5173\u6027\u98ce\u9669<\/div>\n<div>7\u6708\uff0cJAMA oncology\u6742\u5fd7\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u57fa\u4e8e1000\u4e07\u6d3b\u4ea7\u5a74\u513f\u6570\u636e\u5168\u9762\u8bc4\u4f30\u51fa\u751f\u7f3a\u9677\u4e0e\u513f\u7ae5\u671f\u764c\u75c7\u76f8\u5173\u6027\u98ce\u9669\u7684\u6587\u7ae0\uff0c\u7528\u5927\u6570\u636e\u63ed\u793a\u51fa\u751f\u7f3a\u9677\u4e0e\u513f\u7ae5\u671f\u80bf\u7624\u7684\u7279\u6709\u5173\u8054\u3002\uff08\u534e\u5927\u533b\u5b66\uff09<\/div>\n<div>\u00a0<\/div>\n<div>\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u56e2\u961f\u6253\u9020\u201c\u4eba\u9020\u808c\u8089\u201d<\/div>\n<div>7\u670815\u65e5\u6d88\u606f\uff0c\u9ebb\u7701\u7406\u5de5\u5b66\u9662\uff08MIT\uff09\u7684\u7814\u7a76\u56e2\u961f\u5229\u7528\u201c\u70ed\u80c0\u51b7\u7f29\u201d\u7684\u539f\u7406\uff0c\u5236\u9020\u51fa\u4e86\u4e00\u79cd\u4eba\u9020\u808c\u8089\u7ea4\u7ef4\uff0c\u5176\u5355\u6839\u7ea4\u7ef4\u53ef\u627f\u53d7\u81ea\u8eab\u91cd\u91cf 650 \u500d\u7684\u8f7d\u8377\uff0c\u800c\u4e14\u5927\u6982\u6210\u672c\u662f\u6bcf\u7c73 6 \u7f8e\u5206\uff0c\u5df2\u7ecf\u5177\u5907\u5de5\u4e1a\u5316\u89c4\u6a21\u91cf\u4ea7\u7684\u6761\u4ef6\u3002\uff08DeepTech\u6df1\u79d1\u6280\uff09<\/div>\n<div>\u00a0<\/div>\n<div>\u8bc6\u522b\u9488\u5bf9\u764c\u75c7\u7684\u514d\u75ab\u7ec6\u80de\u6761\u5f62\u7801\u8ffd\u8e2a\u7cfb\u7edf<\/div>\n<div>\u6839\u636eNature Communications\uff0c\u6fb3\u5927\u5229\u4e9a\u79d1\u5b66\u5bb6\u5f00\u53d1\u4e86\u4e00\u79cd\u7528\u4e8e\u7ec6\u80de\u7684\u6761\u5f62\u7801\u8ffd\u8e2a\u7cfb\u7edf\uff0cRAGE-Seq\u6280\u672f\u53ef\u4ee5\u751f\u6210\u9ad8\u7cbe\u5ea6\u548c\u9ad8\u7075\u654f\u5ea6\u7684\u5168\u957f\u6297\u539f\u53d7\u4f53\u5e8f\u5217\uff0c\u8bc6\u522b\u9488\u5bf9\u764c\u75c7\u4ea7\u751f\u7684\u7f55\u89c1\u514d\u75ab\u7cfb\u7edf\u7ec6\u80de\u3002<\/div>\n<div>\u00a0<\/div>\n<div>Nature Biotechnology\uff1a\u5b8f\u57fa\u56e0\u7ec4\u5b66\u68c0\u6d4b\u7684\u7814\u7a76<\/div>\n<div>\u8fd1\u65e5\uff0c\u82f1\u56fd\u4e1c\u5b89\u683c\u5229\u4e9a\u5927\u5b66\u7684\u79d1\u5b66\u5bb6\u6210\u529f\u5f00\u53d1\u4e86\u4e00\u79cd\u5b8f\u57fa\u56e0\u7ec4\u5b66\u68c0\u6d4b\u7684\u7814\u7a76\u65b9\u6cd5\u3002\u8be5\u4f18\u5316\u540e\u7684\u7814\u7a76\u65b9\u6848\u9488\u5bf9\u7ec6\u83cc\u6027\u4e0b\u547c\u5438\u9053\u611f\u67d3\uff0c\u53ef\u4ece\u4e34\u5e8a\u547c\u5438\u9053\u6837\u672c\u4e2d\u53bb\u9664\u9ad8\u8fbe99.99\uff05\u7684\u5bbf\u4e3b\u6838\u9178\uff0c\u5e76\u5229\u7528\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u7684\u5b9e\u65f6\u68c0\u6d4b\u57286\u5c0f\u65f6\u5185\u51c6\u786e\u8bc6\u522b\u75c5\u539f\u4f53\u548c\u6297\u751f\u7d20\u6297\u6027\u57fa\u56e0\u3002\uff08OxfordNanopore\uff09<\/div>\n<div>\u00a0<\/div>\n<div>\u300a\u7ec6\u80de\u300b\uff1a\u5efa\u7acb\u764c\u75c7\u60a3\u8005\u957f\u671f\u9884\u540e\u7684\u9884\u6d4b\u6a21\u578b<\/div>\n<div>\u6700\u8fd1\uff0c\u65af\u5766\u798f\u5927\u5b66\u79d1\u5b66\u5bb6\u5f00\u53d1\u4e86\u8fd9\u6837\u4e00\u4e2a\u6c34\u6676\u7403\uff0c\u53eb\u201c\u8fde\u7eed\u4e2a\u4f53\u5316\u98ce\u9669\u6307\u6807\u201d\u6a21\u578b\uff0c\u8fd9\u4e2a\u6a21\u578b\u80fd\u6839\u636e\u4e00\u4e9b\u5b9e\u65f6\u7684\u68c0\u6d4b\u6307\u6807\uff0c\u51c6\u786e\u9884\u6d4b\u764c\u75c7\u75c5\u4eba12-60\u4e2a\u6708\u5185\u7684\u8fdb\u5c55\u98ce\u9669\u3002\u5e76\u4e14\u8fd8\u80fd\u6307\u5bfc\u75c5\u4eba\u91c7\u53d6\u6700\u5408\u9002\u7684\u6cbb\u7597\u65b9\u6cd5\u3002\u76ee\u524d\uff0c\u8be5\u6a21\u578b\u5df2\u5728\u5f25\u6f2b\u6027\u5927B\u7ec6\u80de\u6dcb\u5df4\u7624\u3001\u6162\u6027\u6dcb\u5df4\u7ec6\u80de\u767d\u8840\u75c5\u4ee5\u53ca\u4e73\u817a\u764c\u4e2d\u53d6\u5f97\u4e86\u826f\u597d\u7684\u6548\u679c\uff0c\u76f8\u5173\u7814\u7a76\u53d1\u8868\u5728\u300a\u7ec6\u80de\u300b\u4e0a\u3002\uff08\u5947\u70b9\u7f51\uff09<\/div>\n<div>\u00a0<\/div>\n<div>\u300a\u81ea\u7136\u300b\u5b50\u520a\uff1aEB\u75c5\u6bd2\u611f\u67d3\u53ef\u80fd\u4e0e\u80ba\u6dcb\u5df4\u4e0a\u76ae\u7624\u6837\u764c\u6709\u5173<\/div>\n<div>\u6700\u8fd1\uff0c\u4e2d\u5c71\u5927\u5b66\u7684\u5f20\u529b\u6559\u6388\u56e2\u961f\u548c\u534e\u5927\u57fa\u56e0\u79d1\u7814\u4eba\u5458\u901a\u8fc7\u5168\u5916\u663e\u5b50\u6d4b\u5e8f\u6280\u672f\u53d1\u73b0\uff0c\u4e00\u79cd\u7f55\u89c1\u7684\u80ba\u764c\u7c7b\u578b\u2014\u2014\u80ba\u6dcb\u5df4\u4e0a\u76ae\u7624\u6837\u764c\uff08LELC\uff09\u548c\u9f3b\u54bd\u764c\u4e00\u6837\u4e0eEB\u75c5\u6bd2\u6709\u5f88\u5bc6\u5207\u7684\u5173\u7cfb\u3002\u5e76\u4e14\uff0c\u8fd8\u53d1\u73b0\u76ee\u524d\u7528\u6765\u6cbb\u7597\u9f3b\u54bd\u764c\u7684\u5409\u897f\u4ed6\u6ee8+\u987a\u94c2\u65b9\u6848\uff0c\u5bf9\u80baLELC\u7684\u6cbb\u7597\u6548\u679c\uff0c\u8fd8\u8981\u8fdc\u597d\u4e8e\u73b0\u6709\u7684\u4e00\u7ebf\u65b9\u6848\uff0c\u5927\u5e45\u63d0\u5347\u4e86\u5ba2\u89c2\u7f13\u89e3\u7387\u548c\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u3002\uff08\u5947\u70b9\u7f51\uff09<\/div>\n<div>\u00a0<\/div>\n<div>\u4e2d\u56fd\u524d\u5217\u817a\u764c\u60a3\u8005\u57fa\u56e0\u68c0\u6d4b\u4e13\u5bb6\u5171\u8bc6\uff082019\u5e74\u7248\uff09<\/div>\n<div>\u8fd1\u65e5\uff0c\u300a\u4e2d\u56fd\u524d\u5217\u817a\u764c\u60a3\u8005\u57fa\u56e0\u68c0\u6d4b\u4e13\u5bb6\u5171\u8bc6\uff082019\u5e74\u7248\uff09\u300b\u53d1\u8868\u5728\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u80bf\u7624\u533b\u9662\u4e3b\u529e\u7684\u5168\u56fd\u6027\u80bf\u7624\u5b66\u672f\u671f\u520a\u300a\u4e2d\u56fd\u764c\u75c7\u6742\u5fd7\u300b\u3002\u6700\u65b0\u5171\u8bc6\u63a8\u8350\u4e86\u9002\u5b9c\u8fdb\u884c\u57fa\u56e0\u68c0\u6d4b\u7684\u5bf9\u8c61\u548c\u57fa\u56e0\u68c0\u6d4b\u5185\u5bb9\uff0c\u8fdb\u4e00\u6b65\u6307\u5bfc\u4e86NGS\u57fa\u56e0\u68c0\u6d4b\u5728\u524d\u5217\u817a\u764c\u8bca\u7597\u4e2d\u7684\u89c4\u8303\u5e94\u7528\u3002\uff08\u83b2\u548c\u533b\u7597\uff09<\/div>\n<div>\u00a0<\/div>\n<div>Genmab\u4e0eBliNK Biomedical\u5408\u4f5c\u5f00\u5c55\u764c\u75c7\u6cbb\u7597<\/div>\n<div>7\u670815\u65e5\u6d88\u606f\uff0c\u4e39\u9ea6Genmab\u516c\u53f8\u4e0eBliNK Biomedical\u5408\u4f5c\u63a8\u51fa\u4e86\u9ad8\u8fbe2\u4ebf\u7f8e\u5143\u7684\u764c\u75c7\u6cbb\u7597\u5408\u4f5c\uff0cGenmab\u5df2\u7ecf\u7b7e\u7f72\u4e86\u9488\u5bf9CD47\u7684BliNK Biomedical\u6297\u4f53\u7684\u72ec\u5bb6\u5546\u4e1a\u8bb8\u53ef\uff0cGenmab\u8ba1\u5212\u5c06\u5176\u4e0eDuoBody\u00ae\u5e73\u53f0\u6280\u672f\u76f8\u7ed3\u5408\uff0c\u4ee5\u521b\u9020\u65b0\u7684\u6297\u764c\u53cc\u7279\u5f02\u6027\u6297\u4f53\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u5e15\u91d1\u68ee\u57fa\u91d1\u4f1a\u548cFulgent Genetics\u5408\u4f5c\u5e15\u91d1\u68ee\u75c5\u57fa\u56e0\u68c0\u6d4b\u8ba1\u5212<\/div>\n<div>7\u670816\u65e5\uff0c\u5e15\u91d1\u68ee\u57fa\u91d1\u4f1a\u548cFulgent Genetics\u516c\u53f8\u5ba3\u5e03\uff0c\u4ed6\u4eec\u5df2\u5f00\u59cb\u5c31\u5e15\u91d1\u68ee\u75c5\u60a3\u8005\u7684\u65b0\u57fa\u56e0\u68c0\u6d4b\u8ba1\u5212\u5c55\u5f00\u5408\u4f5c\u3002\u5c06\u4e3a\u5177\u6709\u6f5c\u5728\u4e34\u5e8a\u76f8\u5173\u5e15\u91d1\u68ee\u75c5\u76f8\u5173\u57fa\u56e0\u7684\u4e2a\u4f53\u63d0\u4f9b\u57fa\u56e0\u68c0\u6d4b\u548c\u9057\u4f20\u54a8\u8be2\u3002<\/div>\n<div>\u00a0<\/div>\n<div>Arbor Biosciences\u4e3aIWGSC\u63d0\u4f9b\u5c0f\u9ea6\u57fa\u56e0\u7ec4\u751f\u7269\u4fe1\u606f\u5206\u6790<\/div>\n<div>7\u670816\u65e5\uff0cArbor Biosciences\u8868\u793a\u5df2\u7b7e\u7f72\u534f\u8bae\uff0c\u4e3a\u56fd\u9645\u5c0f\u9ea6\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u534f\u4f1a\uff08IWGSC\uff09\u5f00\u53d1\u7684\u5916\u663e\u5b50\u7ec4\u63d0\u4f9bCurio Genomics\u7684\u751f\u7269\u4fe1\u606f\u5b66\u5e73\u53f0\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u00a0<\/div>\n<div>\u521b\u65b0RNAi\u7597\u6cd5\u83b7FDA\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a<\/div>\n<div>\u8fd1\u65e5\uff0cDicerna Pharmaceuticals\u516c\u53f8\u5ba3\u5e03\uff0c\u7f8e\u56fdFDA\u6388\u4e88\u5176\u5728\u7814RNAi\u7597\u6cd5DCR-PHXC\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u7528\u4e8e\u6cbb\u75971\u578b\u539f\u53d1\u6027\u9ad8\u8349\u9178\u5c3f\u75c7\uff08PH1\uff09\u3002FDA\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u65e8\u5728\u52a0\u5feb\u6cbb\u7597\u4e25\u91cd\u75be\u75c5\u7684\u521b\u65b0\u7597\u6cd5\u7684\u7814\u53d1\u548c\u8bc4\u4f30\u901f\u5ea6\u3002\uff08\u836f\u660e\u5eb7\u5fb7\uff09<\/div>\n<div>\u00a0<\/div>\n<div>Boehringer Ingelheim\u4ee5\u9ad8\u8fbe3.25\u4ebf\u6b27\u5143\u7684\u4ef7\u683c\u6536\u8d2dAMAL Therapeutics<\/div>\n<div>7\u670817\u65e5\u6d88\u606f\uff0cBoehringer Ingelheim\u4ee53.25\u4ebf\u6b27\u5143\uff083.649\u4ebf\u7f8e\u5143\uff09\u7684\u4ef7\u683c\u6536\u8d2d\u745e\u58eb\u65d7\u4e0b\u7684AMAL Therapeutics\u516c\u53f8\uff0c\u8be5\u516c\u53f8\u662f\u57fa\u4e8e\u5176KISIMA\u00ae\u6280\u672f\u5e73\u53f0\u7684\u4e00\u6d41\u764c\u75c7\u75ab\u82d7\u5f00\u53d1\u5546\u3002AMAL\u7684\u4e3b\u8981\u75ab\u82d7\u5019\u9009\u7269ATP128\u662f\u4e00\u79cd\u5d4c\u5408\u91cd\u7ec4\u86cb\u767d\u75ab\u82d7\uff0c\u6b63\u5728\u5f00\u53d1\u7528\u4e8eIV\u9636\u6bb5\u7ed3\u76f4\u80a0\u764c\uff0c\u5e76\u5c06\u5728\u672c\u6708\u665a\u4e9b\u65f6\u5019\u5f00\u59cb\u8fdb\u884c\u9996\u6b21\u4eba\u4f53\u8bd5\u9a8c\u3002<\/div>\n<div>\u00a0<\/div>\n<div>AveXis\u548cParagon\u5408\u4f5cSMA\u57fa\u56e0\u6cbb\u7597<\/div>\n<div>7\u670816\u65e5\uff0c\u8bfa\u534e\u516c\u53f8AVEXIS\u8868\u793a\u5c06\u5229\u7528Paragon\u57fa\u56e0\u6cbb\u7597\u4e2d\u5fc3\u4f5c\u4e3a\u989d\u5916\u7684\u751f\u4ea7\u57fa\u5730\u9488\u5bf9\u5176\u810a\u9ad3\u6027\u808c\u840e\u7f29\u75c7\uff08SMA\uff09\u7684\u57fa\u56e0\u6cbb\u7597Zolgensma\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u57fa\u56e0\u6cf0\u514b\u4e0eSkyhawk\u5728RNA\u6cbb\u7597\u4e0a\u5408\u4f5c\u8d8520\u4ebf\u7f8e\u5143<\/div>\n<div>7\u670816\u65e5\uff0cGenentech\u4e0eGPCR\u4e13\u5bb6Sosei Heptares\u8fbe\u621010\u4ebf\u7f8e\u5143\u7684biobucks\u534f\u8bae\uff0c\u4e4b\u540e\u5408\u4f5c\u4e86\u53e6\u5916\u4e24\u9879\u534f\u8bae\uff1a\u4e00\u4e2a\u4e13\u6ce8\u4e8eSkyhawk Therapeutics\u6cbb\u7597\u764c\u75c7\u548c\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\uff0c\u53e6\u4e00\u4e2a\u4e13\u6ce8\u4e8eConvelo Therapeutics\u6cbb\u7597\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u3002\u8be5\u534f\u8bae\u6388\u4e88Genentech\u72ec\u5bb6\u5168\u7403\u8bb8\u53ef\uff0c\u7528\u4e8e\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u9488\u5bf9\u591a\u4e2a\u76ee\u6807\u7684\u6f5c\u5728\u7597\u6cd5\u3002<\/div>\n<div>\u00a0<\/div>\n<div>Trefoil Therapeutics\u6295\u5165$28M\u5230\u9996\u4e2a\u6cbb\u7597\u9057\u4f20\u6027\u773c\u75be\u7684\u7ec6\u80de\u836f\u7269<\/div>\n<div>7\u670816\u65e5\u6d88\u606f\uff0c\u76ee\u524d\u9884\u9632\u89d2\u819c\u8425\u517b\u4e0d\u826f\u7684\u9057\u4f20\u6027\u773c\u75c5\u60a3\u8005\u5931\u660e\u7684\u552f\u4e00\u65b9\u6cd5\u662f\u4f7f\u7528\u89d2\u819c\u79fb\u690d\u624b\u672f\u3002\u4f46Trefoil Therapeutics\u6b63\u5728\u5bfb\u6c42\u6539\u53d8\u8fd9\u4e00\u72b6\u51b5\u3002\u5b83\u5df2\u7ecf\u7b79\u96c6\u4e862800\u4e07\u7f8e\u5143\u7528\u4e8e\u5c06\u5176\u518d\u751f\u533b\u5b66\u63a8\u5411\u4e34\u5e8a\u3002Trefoil\u7684\u7b2c\u4e00\u4e2a\u76ee\u6807\u662f\u5c06\u5176\u836f\u7269TTHX1114\u7528\u4e8e\u60a3\u6709\u89d2\u819c\u5185\u76ae\u7ec6\u80de\u8425\u517b\u4e0d\u826f\u7684\u60a3\u8005\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u6d77\u533b\u4f1a\u9057\u4f20\u54a8\u8be2\u4ece\u4e1a\u4eba\u5458\u57f9\u8bad\uff0c8\u67082\u65e5-4\u65e5\uff0c\u957f\u6cbb<\/div>\n<div>\u6d77\u5ce1\u4e24\u5cb8\u533b\u836f\u536b\u751f\u4ea4\u6d41\u534f\u4f1a\u9057\u4f20\u4e0e\u751f\u6b96\u4e13\u4e1a\u59d4\u5458\u4f1a\u5b9a\u4e8e2019\u5e748\u67082\u65e5\u81f34\u65e5\u5728\u5c71\u897f\u7701\u957f\u6cbb\u5e02\u53ec\u5f00\u56fd\u5bb6\u7ee7\u7eed\u6559\u80b2\u533b\u5b66\u6559\u80b2\u9879\u76ee\u9057\u4f20\u54a8\u8be2\u4ece\u4e1a\u4eba\u5458\u57f9\u8bad\u73ed\uff08\u7b2c\u5341\u4e94\u671f\uff09\u66a8\u7cbe\u51c6\u533b\u5b66\u6846\u67b6\u4e0b\u51fa\u751f\u7f3a\u9677\u9632\u63a7\u53ca\u4ea7\u524d\u8bca\u65ad\u6280\u672f\u9ad8\u5cf0\u8bba\u575b\uff08\u7b2c\u4e09\u5c4a\uff09\u3002\u6b64\u6b21\u57f9\u8bad\u73ed\u5c06\u4ecb\u7ecd\u6709\u5173\u9057\u4f20\u75c5\u3001\u9057\u4f20\u75c5\u8bca\u65ad\u3001\u9057\u4f20\u54a8\u8be2\u53ca\u4ea7\u524d\u8bca\u65ad\u548c PGD \u64cd\u4f5c\u89c4\u8303\u7b49\u77e5\u8bc6\u3002\u6b64\u6b21\u4f1a\u8bae\u7531\u6d77\u5ce1\u4e24\u5cb8\u533b\u836f\u536b\u751f\u4ea4\u6d41\u534f\u4f1a\u9057\u4f20\u4e0e\u751f\u6b96\u4e13\u4e1a\u59d4\u5458\u4f1a\u4e3b\u529e\uff0cWHO\u9057\u4f20\u75c5\u793e\u533a\u63a7\u5236\u5408\u4f5c\u4e2d\u5fc3\u8054\u5408\u957f\u6cbb\u5e02\u5987\u5e7c\u4fdd\u5065\u9662\u3001\u5c71\u897f\u7701\u533b\u5e08\u534f\u4f1a\u68c0\u9a8c\u533b\u5e08\u5206\u4f1a\u533b\u5b66\u9057\u4f20\u5b66\u4e0e\u8bca\u65ad\u6280\u672f\u4e13\u4e1a\u59d4\u5458\u4f1a\u627f\u529e\u3002\uff08<a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzA4MDQ0NzM1MQ==&amp;mid=2650192124&amp;idx=1&amp;sn=41ef9712fafa87f46b6971a590efa9eb&amp;scene=21#wechat_redirect\">\u8be6\u60c5<\/a>\uff09<\/div>\n<div>\u201c\u9057\u4f20\u4e0e\u4eba\u7c7b\u5065\u5eb7\u201d\u9662\u58eb\u8bba\u575b\uff0c8\u670822\u65e5-8\u670824\u65e5\uff0c\u8d35\u9633<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgBoibxibQnRGrszjh1WnbBb98VaAJf2h5PCf1bm5YyUqqjc5jkb0KicS11ECIjUPDM1rbFx8Lt0tP1kQ.jpeg\" alt=\"RmFicvQBAkgBoibxibQnRGrszjh1WnbBb98VaAJf2h5PCf1bm5YyUqqjc5jkb0KicS11ECIjUPDM1rbFx8Lt0tP1kQ\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>8\u670822\u65e5-24\u65e5\uff0c\u7531\u4e2d\u56fd\u5de5\u7a0b\u9662\u533b\u836f\u536b\u751f\u5b66\u90e8\u548c\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u533b\u5b66\u9057\u4f20\u7814\u7a76\u6240\u4e3b\u529e\u7684\u4e2d\u56fd\u5de5\u7a0b\u96622019\u533b\u5b66\u524d\u6cbf\u8bba\u575b\u5c06\u5728\u8d35\u5dde\u7701\u8d35\u9633\u5e02\u4e3e\u884c\uff0c\u4e03\u4f4d\u9662\u58eb\u9886\u8854\uff0c\u4f01\u4e1a\u8d5e\u52a9\u4ec5\u5269\u9650\u91cf\u540d\u989d\u3002\uff08<a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247494264&amp;idx=1&amp;sn=b0c30b91609466477b1383b92c66d6fe&amp;scene=21#wechat_redirect\" \/>\u8be6\u60c5<\/a>\uff09<\/div>\n<div><\/div>\n<div>\u3010\u58f0\u660e\u3011\u4ee5\u4e0a\u6587\u7ae0\u4e3a\u884c\u4e1a\u76f8\u5173\u8d44\u8baf\u6216\u5206\u6790\uff0c\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u4e0d\u4f5c\u4e3a\u4e34\u5e8a\u7b49\u51b3\u7b56\u4f9d\u636e\uff1b\u7f16\u8f91\u540e\u7684\u6587\u7ae0\u7684\u77e5\u8bc6\u7248\u6743\u5c5e\u4e8e\u57fa\u56e0\u6167\uff0c\u673a\u6784\u8f6c\u8f7d\u8bf7\u5728\u6587\u7ae0\u4f5c\u8005\u4ee5\u53ca\u6b63\u6587\u9996\u884c\u663e\u8457\u6ce8\u660e\u51fa\u5904\uff0c\u6b22\u8fce\u4e2a\u4eba\u8f6c\u53d1\u81f3\u670b\u53cb\u5708\u53ca\u7fa4\u5206\u4eab\u3002<\/div>\n<div><\/div>\n<div><\/div>\n<div><\/div>\n<div>\u57fa\u56e0\u6167\u62db\u8058<\/div>\n<div><\/div>\n<div>1. \u884c\u4e1a\u5206\u6790\u5e08\u00a0\u00a0<\/div>\n<div>\u64b0\u5199\u57fa\u56e0\u53ca\u76f8\u5173\u884c\u4e1a\u5206\u6790\u6587\u7ae0\/\u62a5\u544a\uff0c\u5173\u8054\u884c\u4e1a\u4ea7\u54c1\/\u5e02\u573a\u5de5\u4f5c\u7ecf\u9a8c2y+<\/div>\n<div><\/div>\n<div>2. \u65b0\u5a92\u4f53\u7f16\u8f91<\/div>\n<div>\u65b0\u5a92\u4f53\u6587\u7ae0\u64b0\u5199\u53ca\u516c\u4f17\u53f7\u7b49\u8fd0\u8425\uff0c\u5173\u8054\u884c\u4e1a\u65b0\u5a92\u4f53\/\u5e02\u573a\u5de5\u4f5c\u7ecf\u9a8c1y+<\/div>\n<div><\/div>\n<div>3. \u5546\u52a1\u7ecf\u7406<\/div>\n<div>\u5546\u52a1\u9879\u76ee\u7ba1\u7406\u53ca\u5408\u4f5c\u673a\u4f1a\u5f00\u62d3\uff0c\u5173\u8054\u884c\u4e1a\u5e02\u573a\/\u9500\u552e\u7ecf\u9a8c1y+<\/div>\n<div>\uff08\u7b80\u5386\u6295\u9012\u90ae\u7bb1\uff1ainfo@genonet.cn)<\/div>\n<div><\/div>\n<div><\/div>\n<div><\/div>\n<div>\u00a0\u52a0\u5165\u57fa\u56e0\u6167\u8bfb\u8005\u7fa4\u00a0<\/div>\n<div><\/div>\n<div>\u6dfb\u52a0Mark\u5fae\u4fe1\uff0c\u52a1\u5fc5\u5907\u6ce8\uff1a\u5355\u4f4d-\u804c\u4f4d-\u59d3\u540d<\/div>\n<div>\u901a\u8fc7\u540e\u8d50\u540d\u7247\uff0c\u6838\u5b9e\u540e\u9080\u8bf7\u8fdb\u7fa4<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/mmbiz.qpic.cn\/mmbiz_jpg\/RmFicvQBAkgCIniaBVXdZJGhprQkPPCBddQxw0icic5Z3nzQluvyNB7Rpib69K5AfqwTqF0pk2fLHVuroluTUG7Zwicg\/640?wx_fmt=jpeg\" alt=\"640?wx_fmt=jpeg\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div><\/div>\n<div>\u3010\u5173\u4e8e\u57fa\u56e0\u6167\u3011\u6df1\u5733\u57fa\u56e0\u754c\u79d1\u6280\u54a8\u8be2\u6709\u9650\u516c\u53f8\u662f\u4e00\u5bb6\u7b2c\u4e09\u65b9\u57fa\u56e0\u548c\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u521b\u65b0\u670d\u52a1\u673a\u6784\uff0c\u6210\u7acb\u4e8e2016\u5e74\uff0c\u57fa\u4e8e10\u5e74\u4ea7\u4e1a\u5b9e\u8df5\u7684\u56e2\u961f\uff0c\u6211\u4eec\u5efa\u7acb\u4e86\u884c\u4e1a\u6570\u636e\u5e93YourMap\u548c\u4e13\u4e1a\u5a92\u4f53\u54c1\u724c\u57fa\u56e0\u6167\uff08GeneClub\uff09\uff0c\u63d0\u4f9b\u4ea7\u4e1a\u89c4\u5212\u3001\u54a8\u8be2\u57f9\u8bad\u548c\u79d1\u6280\u5a92\u4f53\u7b49\u670d\u52a1\uff0c\u81f4\u529b\u4e8e\u5efa\u7acb\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u4fe1\u606f\u5927\u6570\u636e\u5e73\u53f0\u3002<\/div>\n<div><\/div>\n<div>\u56fd\u5bb6\u53d1\u6539\u59d4\u300a2019\u5e74\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b\u7f16\u59d4\u7684\u5355\u4f4d<\/div>\n<div>\u5168\u56fd\u536b\u751f\u4ea7\u4e1a\u4f01\u4e1a\u7ba1\u7406\u534f\u4f1a\u7cbe\u51c6\u533b\u7597\u5206\u4f1a\u7406\u4e8b\u7684\u5355\u4f4d<\/div>\n<div>\u54c8\u5c14\u6ee8\u5de5\u4e1a\u5927\u5b66\uff08\u6df1\u5733\uff09\u300a\u751f\u7269\u4ea7\u4e1a\u5206\u6790\u300b\u8bfe\u7a0b\u5408\u4f5c\u5355\u4f4d<\/div>\n<div><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247492916&amp;idx=1&amp;sn=a95b284c253aeeeea58a406317f2e88a&amp;chksm=eb715783dc06de95fe5994aacbd3632ba0402915a8fb4a5f44423437eca4bd8461639998cc40&amp;scene=21#wechat_redirect\" \/>\u300a\u4e34\u5e8a\u751f\u7269\u6837\u672c\u5e93\u63a2\u7d22\u4e0e\u5b9e\u8df5<\/a>\u300b\u7684\u7f16\u59d4\u5355\u4f4d<\/div>\n<div>\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5b66\u4f1a\u653f\u7b56\u7814\u7a76\u5206\u4f1a\u5e38\u59d4\u7684\u5355\u4f4d<\/div>\n<div>\u6df1\u5733\u5e02\u5065\u5eb7\u4ea7\u4e1a\u53d1\u5c55\u4fc3\u8fdb\u4f1a\u526f\u4f1a\u957f\u5355\u4f4d<\/div>\n<div>\u53d1\u5e03\u4e86<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247493095&amp;idx=1&amp;sn=86d94a4dd4f7a9629a7f30f8c9bd761c&amp;chksm=eb715750dc06de4680bc88f2be4e00c3320074a0edd4c91393590a7518b890383fb1a5c88343&amp;scene=21#wechat_redirect\" \/>\u300a2019 \u5e74\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b<\/a>\u7b49\u884c\u4e1a\u62a5\u544a<\/div>\n<div>\u53c2\u4e0e\u7ec4\u7ec7\u9996\u4e2a<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247487811&amp;idx=1&amp;sn=54fe9c1cef11de022168ef5c55dc0efb&amp;chksm=eb72a3f4dc052ae21d2577929f563ff06c451d7f6872fa954270530468187cc5844ba5ade4d3&amp;scene=21#wechat_redirect\" \/>\u300a\u4e34\u5e8a\u57fa\u56e0\u68c0\u6d4b\u62a5\u544a\u89c4\u8303\u4e0e\u57fa\u56e0\u68c0\u6d4b\u884c\u4e1a\u5171\u8bc6\u300b<\/a>\u53ca\u76f8\u5173\u56e2\u6807<\/div>\n<div>\u4e3b\u529e<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247488145&amp;idx=1&amp;sn=d62b3d6ead2512e2c448d9a9ee9ab61f&amp;chksm=eb72a026dc052930fc4a58ec38fb718549780823661d0e67740c037a222066010d10f220fa6f&amp;scene=21#wechat_redirect\" \/>\u9996\u5c4a\u6570\u5b57\u5065\u5eb7\u79c1\u8463\u4f1a<\/a><\/div>\n<div><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247490769&amp;idx=1&amp;sn=36fa39011eb7dd4b148b072d1aadb14c&amp;chksm=eb72ae66dc052770f2c4fc77a777dff121302dbf954b941b54da1d7eaf7eca1fdce86097ee84&amp;scene=21#wechat_redirect\" \/>\u4e3b\u529e\u9996\u5c4a\u7ca4\u6e2f\u6fb3\u5927\u6e7e\u533a\u751f\u547d\u5065\u5eb7\u521b\u65b0\u8bba\u575b<\/a><\/div>\n<div><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247485809&amp;idx=1&amp;sn=ed212d2f2640470ee7269e9959868dcc&amp;chksm=eb72bbc6dc0532d0fea4edea3a9b2aaf23affe391982bdf651b0322120844c1546119d1d475a&amp;scene=21#wechat_redirect\" \/>\u534f\u529e\u7b2c\u4e00\u5c4a<\/a>\u548c<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247493932&amp;idx=1&amp;sn=7e68c7e9c7d5b5479e6e4aa540ca569f&amp;chksm=eb715b9bdc06d28d4944c5584d99a68977413620e4dfbb4716376a4b8a5ce7b6b1b1129b5d4f&amp;scene=21#wechat_redirect\" \/>\u7b2c\u4e8c\u5c4a\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\u5927\u4f1a<\/a><\/div>\n<div><\/div>\n<div>\u6b22\u8fce\u4ea7\u4e1a\u56ed\u533a\u3001\u91d1\u878d\u673a\u6784\u3001\u5b66\u4f1a\u53ca\u8054\u76df\u3001\u653f\u5e9c\u53ca\u4f01\u4e1a\u7b49\u673a\u6784\u5408\u4f5c\uff0c\u878d\u5408\u53d1\u5c55\uff0c\u8d4b\u80fd\u521b\u65b0\uff08400-088-7466\uff0cinfo@genonet.cn\uff09\u3002<\/div>\n<div><\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDwDDlibn6LGMERd60A1XgibkVTEVrPEb1EoTK1HnjticKMtrzWS4eyuZgibs4H2ErBL6cp0GRTKvEAkg.jpeg\" 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