{"id":9235,"date":"2019-08-20T13:39:34","date_gmt":"2019-08-20T05:39:34","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100010774&idx=1&sn=07be92bc20038dc42fb63b28ba2f58b4&chksm=6b7159a15c06d0b7d5fbc45a1e2c8bdc5b36dfff8564c2aed1df2a853863b16567c6fad00c1b#rd"},"modified":"2026-04-08T10:19:18","modified_gmt":"2026-04-08T02:19:18","slug":"5510157","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2019\/08\/20\/5510157\/","title":{"rendered":"2019\u5e74\u534a\u7a0b\uff0c\u57fa\u56e0\u4ea7\u4e1a\u7684\u9ece\u660e\u524d\u9759\u6084\u6084\uff08\u4e0a\uff09"},"content":{"rendered":"

<\/p>\n

\u5173\u952e\u8bcd\/\u57fa\u56e0\u884c\u4e1a\u76d8\u70b9 \u6587\/\u57fa\u56e0\u6167<\/div>\n
2019\u5e74\u8fc7\u534a\uff0c\u57fa\u56e0\u4ea7\u4e1a\u9ece\u660e\u524d\u9759\u6084\u6084\u3002\u884c\u4e1a\u6280\u672f\u9012\u8fdb\u540c\u65f6\u8f6c\u5316\u653e\u7f13\uff0c\u6295\u8d44\u9891\u6b21\u540c\u6bd4\u9510\u51cf\uff0c\u52a0\u901f\u6d17\u724c\uff1b\u800c\u56fd\u5185\u8fc7\u4ebf\u5143\u878d\u8d44\u67097\u8d77\uff0c\u4e8c\u7ea7\u5e02\u573a\u4ecd\u6301\u8f83\u9ad8\u4fe1\u5fc3\uff0c\u591a\u5bb6Pre-IPO\u548c\u5e76\u8d2d\u8fdb\u884c\uff0c\u4e0b\u4e00\u62e8\u6d6a\u6f6e\u6b63\u5728\u915d\u917f\uff0c\u884c\u4e1a\u53d1\u5c55\u7684\u672c\u8d28\u662f\u4ec0\u4e48\uff1f\u8c01\u5728\u521b\u9020\u98ce\u53e3\uff1f\uff08\u6b22\u8fce\u7559\u8a00\u8ba8\u8bba\uff0c\u5b8c\u6574\u6587\u7ae0\u53ca\u7cbe\u5f69\u7559\u8a00\u5c06\u520a\u767b\u5728\u57fa\u56e0\u6167\u5c06\u53d1\u5e03\u7684\u300a\u78b1\u62a5\u300b01\u671fPDF\u3002\uff09<\/div>\n\n
\n
\"0?wx_fmt=jpeg\"\/<\/figure><\/div>\n\n
\u56fe:\u56fe\u4e66\u300a\u8fd9\u91cc\u7684\u9ece\u660e\u9759\u6084\u6084\u300b\u5c01\u9762\uff08\u6765\u81ea\u4e92\u8054\u7f51\uff09<\/div>\n
\u5212\u91cd\u70b9<\/div>\n
\u672c\u6587\u5185\u5bb9\u8f83\u957f\uff0c\u5217\u660e\u76ee\u5f55\u5982\u4e0b\uff1a<\/div>\n
1. \u57fa\u56e0\u4ea7\u4e1a\u7684\u5185\u5728\u57fa\u77f3\u548c\u5916\u5728\u6846\u67b6\u00a0<\/div>\n
2. \u57fa\u56e0\u4ea7\u4e1a\u94fe\u7684\u201c\u53d8\u201d\u548c\u201c\u4e0d\u53d8\u201d\u00a0<\/div>\n
3. 2019\uff08\u4e0a\uff09\u57fa\u56e0\u884c\u4e1a\u6295\u878d\u8d44\u56fe\u8c31\u00a0<\/div>\n
4. \u65e7\u8fb9\u754c\u7684\u6253\u7834\uff0c\u65b0\u8d5b\u9053\u7684\u5d1b\u8d77\u00a0<\/div>\n
5. \u5e76\u8d2d\u6d45\u6790\u00a0<\/div>\n
6. \u4e0a\u5e02\u4f01\u4e1a\u6570\u636e\u6d45\u6790\u00a0\u00a0<\/div>\n
7. \u51c6\u4e0a\u5e02\u4f01\u4e1a\u6d45\u6790\u00a0<\/div>\n
8.\u00a0\u672a\u6765\u53d1\u5c55\u8d8b\u52bf\u7684\u601d\u8003<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u7684\u5386\u53f2\u5f80\u5f80\u90fd\u662f\u60ca\u4eba\u7684\u76f8\u4f3c\uff0c\u6545\u4e8b\u5f80\u5f80\u4e0d\u662f\u4e00\u5f00\u59cb\u5c31\u5199\u597d\u7684\u3002<\/div>\n
1994\u5e74\uff0c\u968f\u7740\u7f51\u666f\u6d4f\u89c8\u5668\u53ca\u4e07\u7ef4\u7f51\u7684\u51fa\u73b0\uff0c\u4e92\u8054\u7f51\u6a21\u5f0f\u4f7f\u5f53\u65f6\u7684\u4eba\u4eec\u6b22\u6b23\u9f13\u821e\u770b\u5230\u5bf9\u5e7f\u544a\u4e1a\u3001\u9500\u552e\u3001\u901a\u8baf\u3001\u51fa\u7248\u7b49\u7684\u9769\u65b0\uff0c\u968f\u5373\u6380\u8d77\u4e92\u8054\u7f51\u7f51\u7edc\u57fa\u5efa\u3001\u8f6f\u4ef6\u53ca\u95e8\u6237\u7f51\u7ad9\u7684\u6d6a\u6f6e\u3002\u4ec5\u4ec56\u5e74\u540e\uff0c\u4e92\u8054\u7f51\u6ce1\u6cab\u7834\u88c2\uff0c\u4e0a\u4e07\u4ebf\u7f8e\u5143\u5e02\u503c\u6e6e\u706d\u3002<\/div>\n
\u4ece\u53e6\u5916\u4e00\u4e2a\u7ef4\u5ea6\uff0c\u7f51\u6613\u662f\u5f53\u65f6\u56fd\u5185\u4e09\u5927\u95e8\u6237\u7f51\u7ad9\u6700\u60e8\u7684\uff0c\u5982\u4eca\u8f6c\u578b\u6700\u5feb\uff1b\u66fe\u7ecf\u7684\u7535\u5b50\u5546\u52a1\u65d7\u82308848\u5982\u4eca\u6773\u65e0\u8e2a\u8ff9\uff1b\u817e\u8baf\u6700\u65e9\u60f3\u7ed9\u7535\u4fe1\u505a\u7f51\u7edc\u5bfb\u547c\u7cfb\u7edf\uff1b\u963f\u91cc\u5df4\u5df4\u6700\u5f00\u59cb\u505a\u4f01\u4e1a\u9ec4\u9875\uff1b\u5947\u864e360\u6700\u5f00\u59cb\u505a\u793e\u533a\u641c\u7d22\u3002<\/div>\n
\u00a0<\/div>\n
\u57fa\u56e0\u4ea7\u4e1a\u662f\u5426\u4e5f\u5c06\u7ecf\u5386\u7c7b\u4f3c\u7684\u6d6a\u6f6e\uff1f<\/div>\n
\u57fa\u56e0\u884c\u4e1a\u56e0\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u5f97\u5230\u5b98\u65b9\u5173\u6ce8\uff0c\u7531\u4e8eNGS\u6280\u672f\u5f97\u5230\u6548\u7387\u63d0\u5347\uff0c\u968f\u77402007\u5e74Illumina\u6536\u8d2dSolexa\u3001\u534e\u5927\u57fa\u56e0\uff08BGI\uff09\u4ece\u4e2d\u79d1\u9662\u4f53\u5236\u8131\u79bb\u5357\u4e0b\u6df1\u5733\u6210\u7acb\u6c11\u4f01\u4f01\u4e1a\uff082019\u5e74\u66f4\u540d\u4e3a\u201c\u534e\u5927\u201d\uff0c\u5373BGI Group\uff09\uff0c2008\u5e74ABI\u4e0eInvitroge\u5408\u5e76\u4e3aLife Technologies\uff08\u540e\u8005\u88abRoche\u6536\u8d2d\uff09\u7b49\u7cfb\u5217\u4e8b\u4ef6\uff0c\u5f00\u59cb\u6b63\u5f0f\u8fdb\u5165\u5927\u89c4\u6a21\u4ea7\u4e1a\u5316\u300212\u5e74\u5386\u53f2\u7684\u9ad8\u901a\u91cf\u57fa\u56e0\u4ea7\u4e1a\uff0c\u5728\u6d4b\u5e8f\u751f\u4ea7\u4e0a\u867d\u8d85\u6469\u5c14\u5b9a\u5f8b\u63d0\u5347\uff0c\u4f46\u4ecd\u662f\u4e2a\u5c11\u5e74\u5c1a\u672a\u6210\u719f\u30022019\u5e74\u534a\u7a0b\uff0c\u57282015-2018\u5e74\u7684\u201c\u70ed\u94b1\u201d\u8fc7\u540e\uff0c\u8fdb\u5165\u6d17\u724c\u671f\uff0c\u4e0b\u4e00\u4e2a\u6d6a\u6f6e\u6b63\u5728\u915d\u917f\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u4e00\u00a0\u00a0\u00a0\u57fa\u56e0\u4ea7\u4e1a\u7684\u5185\u5728\u57fa\u77f3\u548c\u5916\u5728\u6846\u67b6<\/div>\n
2019\u5e74\u6625\u8282\u8fc7\u540e\u7684\u7b2c\u4e8c\u5468\uff0c\u56fd\u52a1\u9662\u53d1\u5e03\u300a\u7ca4\u6e2f\u6fb3\u5927\u6e7e\u533a\u53d1\u5c55\u89c4\u5212\u7eb2\u8981\u300b\uff0c\u5176\u4e2d\u751f\u7269\u6280\u672f\u5217\u4e3a\u56db\u5927\u65b0\u652f\u67f1\u4ea7\u4e1a\u4e4b\u4e00\uff0c\u57fa\u56e0\u68c0\u6d4b\u4f5c\u4e3a\u5341\u5927\u91cd\u5927\u4ea7\u4e1a\u9879\u76ee\u4e4b\u4e00\uff0c\u4e0e5G\u5e76\u5217\u3002\u8fd9\u4e4b\u524d\u53d1\u5e03\u7684\u300a\u6cb3\u5317\u96c4\u5b89\u65b0\u533a\u89c4\u5212\u7eb2\u8981\u300b\u91cc\uff0c\u201c\u73b0\u4ee3\u751f\u547d\u79d1\u5b66\u548c\u751f\u7269\u6280\u672f\u201d\u4f5c\u4e3a\u4e94\u5927\u4ea7\u4e1a\u53d1\u5c55\u91cd\u70b9\u4e4b\u4e00\u3002\u57fa\u56e0\u4ea7\u4e1a\u7684\u6218\u7565\u9ad8\u5ea6\u88ab\u518d\u6b21\u5370\u8bc1\u3002<\/div>\n
\u00a0<\/div>\n
\u7d27\u63a5\u7740\uff0c\u5730\u65b9\u653f\u5e9c\u7684\u7ecf\u4fc3\u5c40\u5206\u62c6\u51fa\u5206\u7ba1\u65b0\u5174\u4ea7\u4e1a\u7684\u79d1\u6280\u5c40\u4e4b\u9645\uff0c\u201c\u751f\u547d\u5065\u5eb7\u529e\u201d\u8fd9\u4e2a\u65b0\u7684\u673a\u6784\u540d\u79f0\u5f00\u59cb\u8bde\u751f\u3002\u5f53\u5965\u5df4\u9a6c\u653f\u5e9c2015\u5e74\u63d0\u51fa\u7684\u201c\u7cbe\u51c6\u533b\u7597\u201d\u6f14\u53d8\u6210\u201c\u5168\u6c11\u5065\u5eb7\u201d\u540e\uff0c\u56fd\u5185\u201c\u7cbe\u51c6\u533b\u7597\u201d\u70ed\u4e864\u5e74\uff0c\u6539\u5934\u6362\u9762\u6210\u201c\u751f\u547d\u5065\u5eb7\u201d\uff0c\u8fd9\u5e76\u975e\u8ddf\u968f\uff0c\u201c\u9884\u9632\u4e3a\u4e3b\u201d\u4e00\u76f4\u662f\u6211\u56fd1997\u5e74\u591a\u4e2a\u536b\u751f\u6587\u4ef6\u7684\u7eb2\u9886\uff0c\u800c\u5728\u8fd1\u5e74\u53d6\u6d88\u4ee5\u836f\u517b\u533b\u3001\u533b\u4fdd\u6c60\u5316\u7684\u5951\u673a\u4e0b\uff0c2019\u5e747\u670815\u65e5\u53d1\u5e03\u7684\u300a\u56fd\u52a1\u9662\u5173\u4e8e\u5b9e\u65bd\u5065\u5eb7\u4e2d\u56fd\u884c\u52a8\u7684\u610f\u89c1\u300b\u6b63\u6587\u7b2c\u4e8c\u53e5\u4fbf\u662f\uff1a<\/div>\n
\u00a0<\/div>\n
\u201c\u9884\u9632\u662f\u6700\u7ecf\u6d4e\u6700\u6709\u6548\u7684\u5065\u5eb7\u7b56\u7565\u201d\u3002<\/div>\n
\u8fd9\u4efd\u91cd\u8981\u6587\u4ef6\u9610\u8ff0\u201c\u9884\u9632\u201d\uff0c\u9664\u4e86\u4f20\u7edf\u7684\u8425\u517b\u4fdd\u5065\u5916\uff0c\u7279\u522b\u63d0\u51fa\u7ef4\u62a4\u5168\u751f\u547d\u5468\u671f\uff08\u5c24\u5176\u662f\u5987\u5e7c\u8001\u5e74\u4eba\u7fa4\uff09\u548c\u9632\u63a7\u91cd\u5927\u75be\u75c5\u3002\u8fd9\u5b9e\u65bd\u8fc7\u7a0b\u4e2d\u7684\u65b0\u5143\u7d20\u662f\u201c\u751f\u547d\u4fe1\u606f\u201d\uff0c\u57fa\u4e8e\u6b64\u8fdb\u884c\u65b0\u751f\u513f\u7b5b\u67e5\u3001\u5efa\u6863\u3001\u51fa\u751f\u7f3a\u9677\u7b5b\u67e5\u3001\u8001\u5e74\u764c\u75c7\u53ca\u5176\u4ed6\u75be\u75c5\u65e9\u8bca\u65e9\u7b5b\u3002\u5728\u751f\u547d\u4fe1\u606f\u7684\u5206\u5b50\u5c42\u9762\uff0c\u4ece\u65e9\u671f\u201c\u7ec8\u7aef\u201d\u7684\u86cb\u767d\u6807\u5fd7\u7269\uff0c\u91cd\u70b9\u504f\u5411\u5230\u201c\u521d\u59cb\u7aef\u201d\u7684\u57fa\u56e0\u7ec4\uff0c\u5176\u6b21\u5305\u62ec\u5fae\u751f\u7269\u7ec4\u3001\u4ee3\u8c22\u7ec4\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u8fd9\u662f\u4e0b\u9762\u548c\u672a\u6765\u6240\u6709\u6545\u4e8b\u7684\u5185\u5728\u57fa\u77f3\uff0c\u90a3\u5916\u5728\u6846\u67b6\u5462\uff1f<\/div>\n
\u4eca\u5e74\uff0c\u7f8e\u56fd\u77ed\u671f\u56fd\u503a\u4e0e\u5341\u5e74\u671f\u56fd\u503a\u6536\u76ca\u7387\u66f2\u7ebf\u5012\u6302\uff0c\u7ecf\u6d4e\u4e0b\u884c\u4e4b\u52bf\u4e9f\u9700\u5bfb\u627e\u65b0\u7684\u589e\u957f\u70b9\u3002\u540c\u65f6\uff0c\u5728\u5168\u7403\u5730\u7f18\u653f\u6cbb\u4e0b\uff0c\u8d38\u6613\u6469\u64e6\u5e76\u975e\u4e00\u65f6\u5174\u8d77\u3002\u4eca\u5e745\u6708\u7f8e\u56fd\u516c\u5e03\u7684\u6d88\u606f\u91cc\uff0c\u8bca\u65ad\u8bd5\u5242\u5217\u5165\u52a0\u5f8125%\u5173\u7a0e\u7a0e\u7387\u7684\u5546\u54c1\u8303\u56f4<\/a>\uff0c\u800c\u5728\u57fa\u56e0\u4ea7\u4e1a\u91cc\uff0c\u4eea\u5668\u6298\u65e7\u548c\u8bd5\u5242\u8017\u6750\u5360\u636e\u6210\u672c\u76841\/3\u4ee5\u4e0a\uff0c\u8fd9\u57282016\u5e74\u4e4b\u524d\u51e0\u4e4e\u5b8c\u5168\u4f9d\u9760\u8fdb\u53e3\uff0c\u5c24\u5176\u662f\u6d4b\u5e8f\u4eea\u3002\u5728\u9ad8\u7cbe\u5bc6\u4eea\u5668\u4ea7\u4e1a\u94fe\u7684\u532e\u4e4f\u6761\u4ef6\u4e0b\uff0c\u56fd\u5185\u57fa\u56e0\u9f99\u5934\u534e\u5927\u5f88\u65e9\u63d0\u51fa\u72ec\u7acb\u7814\u53d1\u6d4b\u5e8f\u4eea\u672a\u679c\uff0c\u800c\u4e4b\u540e\u901a\u8fc7\u5e76\u8d2dComplete Genomics\u5b8c\u6210\u8fd9\u4e2a\u6838\u5fc3\u73af\u8282\u7684\u4ece\u8ddf\u8dd1\u5230\u5e76\u8dd1\uff0c\u5728\u56fd\u5185\u5f00\u542f\u4e00\u4e2a\u65b0\u5174\u4ea7\u4e1a\uff0c\u8fd9\u662f\u540e\u8bdd\u3002<\/div>\n
\u00a0<\/div>\n
\u56de\u52302016\u5e74\u4e4b\u524d\uff0c\u5c3d\u7ba1\u53d1\u5e03\u7684SCI\u5c01\u9762\u6587\u7ae0\u8d34\u4e86\u4e00\u5899\u53c8\u4e00\u5899\uff0c\u51ed\u6b64\uff0c\u5ba2\u6237\u4e0a\u5c97\uff0c\u4f01\u4e1a\u4e0a\u5e02\uff0c\u4f46\u4f9d\u8d56\u7684\u662f\u4e3e\u5730\u65b9\u653f\u5e9c\u4e4b\u529b\u4e3a\u4e00\u4e2a\u53c8\u4e00\u4e2a\u65b0\u7269\u79cd\u7684\u57fa\u56e0\u7ec4\u7d20\u63cf\uff0c\u6838\u5fc3\u6295\u5165\u662f\u6d4b\u5e8f\u751f\u4ea7\uff0c\u6838\u5fc3\u6807\u51c6\u662fSCI\u6587\u7ae0\u548c\u79d1\u7814\u8bc4\u4ef7\u4f53\u5236\uff0c\u5c1a\u672a\u505a\u5230\u5355\u70b9\u6df1\u8015\uff0c\u56e0\u6b64\u8f6c\u5316\u8f83\u6162\uff0c\u4ee5\u76ee\u524d\u4ec5\u4ec5\u6210\u719f\u7684\u4e24\u4e2a\u5e94\u7528\u4e4b\u4e00NIPT\uff08\u65e0\u521b\u4ea7\u524d\u57fa\u56e0\u68c0\u6d4b\uff09\u4e3a\u4f8b\uff0c\u6765\u81ea\u9999\u6e2f\u4e2d\u6587\u5927\u5b66\u7684\u5362\u715c\u660e\u81ea1989-1997\u5e74\u7684\u516b\u5e74\u79d1\u7814\uff0c2007-2010\u5e74\u7684\u4e09\u5e74\u9a8c\u8bc1\uff0c\u624d\u6210\u4e3a\u5982\u4eca\u4e3a\u8d85\u8fc7\u5343\u4e07\u540d\u5b55\u5987\u670d\u52a1\u7684\u201c\u7206\u6b3e\u201d\u4ea7\u54c1\u3002\u5176\u4ed6\u8bf8\u591a\u8d5b\u9053\u4ecd\u9700\u8981\u57fa\u7840\u79d1\u7814\u3001\u8f6c\u5316\u4f53\u7cfb\u4ee5\u53ca\u5b8c\u6574\u4ea7\u4e1a\u94fe\u7684\u5efa\u8bbe\u548c\u7ed3\u5408\u3002<\/div>\n
\u00a0<\/div>\n
\u57fa\u56e0\u4ea7\u4e1a\u662f\u79d1\u7814\u3001\u4e34\u5e8a\u3001\u5de5\u4e1a\u548c\u4ea7\u4e1a\u7ed3\u5408\u7684\u5fc5\u7136\uff0c\u540c\u65f6\u53cd\u54fa\u5efa\u7acb\u77e5\u8bc6\u4ea7\u6743\u3001\u4e34\u5e8a\u5e94\u7528\u3001\u5de5\u4e1a\u667a\u80fd\u548c\u65b0\u5174\u4ea7\u4e1a\u96c6\u7fa4\u3002\u5728\u5df2\u6709\u57fa\u7840\u4e0a\uff0c\u57fa\u56e0\u4ea7\u4e1a\u662f\u6211\u56fd\u9664\u4e86\u9ad8\u94c1\u30015G\u4e4b\u5916\u53ef\u4ee5\u5f15\u9886\u4e16\u754c\u7684\u4e0d\u53ef\u591a\u5f97\u7684\u4ea7\u4e1a\u673a\u9047\u4e4b\u4e00\u3002\u8fd9\u662f\u57fa\u56e0\u4ea7\u4e1a\u53d1\u5c55\u5916\u5728\u6846\u67b6\u5176\u4e00\u3002<\/div>\n
\u00a0<\/div>\n
\u4e0a\u8ff0\u201c\u5176\u4e00\u201d\u5982\u679c\u8fc7\u4e86\uff0c\u5bb9\u6613\u4e3e\u6c11\u65cf\u5927\u65d7\u800c\u9677\u5165\u81ea\u95ed\uff0c\u4e14\u4e0d\u8c08\u56fd\u5185\u7814\u53d1\u3001\u4ea7\u54c1\u8bbe\u8ba1\u7b49\u9ad8\u7aef\u4eba\u624d\u532e\u4e4f\uff0c\u8bba\u6838\u5fc3\u516c\u5171\u6570\u636e\u5e93\u3001\u6295\u878d\u8d44\u53ca\u6d4b\u5e8f\u4eea\u82af\u7247\uff0c\u5747\u4f9d\u8d56\u5168\u7403\u79d1\u7814\u5708\u53ca\u4ea7\u4e1a\u94fe\u5408\u4f5c\u3002\u597d\u5728\u6211\u4eec\u770b\u5230\u4e86\u5176\u4e8c\uff1a\u4ea7\u4e1a\u5408\u4f5c\u53ca\u91d1\u878d\u5f00\u653e\u3002<\/div>\n
\u00a0<\/div>\n
\u8fd1\u5e74\uff0cIllumina\u3001Thermo Fisher\uff08\u8d5b\u9ed8\u98de\uff09\u3001\u00a0Roche\u00a0Diagnostics\u00a0\uff08\u7f57\u6c0f\u8bca\u65ad\uff09\u4e0e\u591a\u5bb6\u672c\u571f\u4f01\u4e1a\u5c55\u5f00\u6218\u7565\u5408\u4f5c\uff0c\u5305\u62ec\u8bbe\u5907OEM\u3001\u4ea7\u54c1\u8bbe\u8ba1\u53ca\u6388\u6743\u7b49\u3002\u800cRoche\u6536\u8d2dFoundation Medicine\uff08FMI\uff09\u540e\uff0c\u5728\u4e4b\u524d\u4e0e\u660e\u7801\u751f\u7269\u79d1\u6280\u5408\u4f5c\u96be\u4ea7\u540e\uff0c\u7275\u624b\u8fea\u5b89\u8bca\u65ad\u5c06\u65d7\u4e0bFMI\u7684\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u5f15\u5165\u4e2d\u56fd\u3002\u5728PacBio\u5ba3\u5e03\u5c06\u88abIllumina\u6536\u8d2d\u540e\uff0c\u4e13\u6ce8\u7eb3\u7c73\u5b54\u4e09\u4ee3\u6d4b\u5e8f\u7684Oxford Nanopore\uff08ONT\uff09\u5feb\u901f\u62d3\u5c55\u4e2d\u56fd\u5e02\u573a\uff0c\u5e76\u4e0e\u5e0c\u671b\u7ec4\u7ed3\u6210\u6218\u7565\u8054\u76df\u3002<\/div>\n
\u00a0<\/div>\n
\u4e0a\u6d77\u7ee7\u5f15\u8fdb\u7279\u65af\u62c9\u540e\uff0c\u65e5\u524d\u5ba3\u5e03\u4e89\u53d6\u5141\u8bb8\u5916\u5546\u6295\u8d44\u4eba\u4f53\u5e72\u7ec6\u80de\u3001\u57fa\u56e0\u8bca\u65ad\u4e0e\u6cbb\u7597\u6280\u672f\u5f00\u53d1\u548c\u5e94\u7528\uff08\u201c\u4e89\u53d6\u201d\u7684\u8bed\u6c14\u6216\u9700\u548c\u201c\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u7ba1\u7406<\/a>\u201d\u653f\u7b56\u76f8\u7b26\uff09\u3002Illumina\u4e5f\u4e8e\u65e5\u524d\u4ee5\u201c\u56e0\u7f8e\u7eb3\u201d\u4e2d\u6587\u54c1\u724c\u5b8c\u6210\u4e86\u56e0\u7f8e\u7eb3\uff08\u4e2d\u56fd\uff09\u79d1\u5b66\u5668\u6750\u6709\u9650\u516c\u53f8\u7684\u6ce8\u518c\uff0c\u53ef\u4ee5\u5f00\u5c55\u4eba\u6c11\u5e01\u4e1a\u52a1\uff0c\u5e76\u5c06\u8bd5\u8fd0\u8425\u65d7\u4e0b\u7684\u4e2d\u56fd\u914d\u9001\u4e2d\u5fc3\u3002\u5728\u6295\u8d44\u4e0a\uff0c\u836f\u660e\u5eb7\u5fb7\u65d7\u4e0b\u7684\u6bd3\u627f\u8d44\u672c\uff08WuXi Healthcare Ventures\uff09\u4e0e\u901a\u548c\u8d44\u672c\u5408\u5e76\u4e3a\u901a\u548c\u6bd3\u627f\uff086 Dimensions Capital\uff09\u6295\u8d44\u4e86\u8d85\u8fc720\u5bb6\u6d77\u5916\u4f01\u4e1a\uff0c\u5305\u62ec\u77e5\u540d\u768423andme\u3001FMI\u3001DNAnexus\u7b49\u3002\u534e\u5927\u65d7\u4e0b\u7684\u57fa\u91d1\u4e5f\u6b63\u5e03\u5c40\u6295\u8d44\u6d77\u5916\u3002\u800c\u5438\u5f15\u6d77\u5916\u8d44\u672c\u4e0a\uff0c\u8001\u724c\u6295\u8d44\u516c\u53f8Temasek\uff08\u6de1\u9a6c\u9521\uff09\u548cArch Venture Partners\u662f\u5404\u8d5b\u9053\u4ee3\u8868\u4f01\u4e1a\u660e\u7801\u751f\u7269\u79d1\u6280\u3001\u57fa\u51c6\u533b\u7597\u3001\u542f\u51fd\u751f\u7269\u7684\u80a1\u4e1c\u3002\u65e0\u8bba\u662f\u6e2f\u80a1\u884c\u653f\u8fd8\u662f\u79d1\u521b\u677f\uff0c\u5747\u5bf9\u751f\u7269\u79d1\u6280\u7c7b\u4f01\u4e1a\u4f38\u51fa\u4e86\u6a44\u6984\u679d\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u4e8c\u00a0\u00a0\u00a0\u57fa\u56e0\u4ea7\u4e1a\u94fe\u7684\u201c\u53d8\u201d\u548c\u201c\u4e0d\u53d8\u201d<\/div>\n
\u5728\u4ee5\u4e0a\u7684\u5185\u5728\u533b\u836f\u536b\u751f\u6539\u9769\u7684\u5185\u5728\u57fa\u77f3\u4ee5\u53ca\u4ea7\u4e1a\u6539\u9769\u3001\u91d1\u878d\u5f00\u653e\u7684\u5916\u5728\u6846\u67b6\u4e0b\uff0c\u6211\u4eec\u56de\u5230\u4ea7\u4e1a\u5185\u90e8\u770b\u770b\u5176\u4e2d\u7684\u201c\u53d8\u201d\u548c\u201c\u4e0d\u53d8\u201d\u3002\u4ece\u4ea7\u4e1a\u94fe\u7531\u4e0a\u5f80\u4e0b\u7b80\u8981\u5206\u6790\u3002<\/div>\n
\u00a0<\/div>\n
\u4e0a\u6e38\u7684\u57fa\u56e0\u6570\u636e\u751f\u4ea7\u4e0a\uff0c\u81ea2016\u5e74\u91cf\u4ea7\u6d4b\u5e8f\u4eea\u540e\uff0c\u534e\u5927\u667a\u9020\uff08MGI\uff09\u52bf\u5982\u7834\u7af9\uff0c\u4f5c\u4e3a\u534e\u5927\u96c6\u56e2\u7684\u6838\u5fc3\u90e8\u5206\u5728\u9996\u8f6e\u878d\u8d442\u4ebf\u5143\u540e\uff0c\u5feb\u901f\u5e03\u5c40\u5305\u62ec\u65e5\u672c\u3001\u5357\u975e\u3001\u4e1c\u5357\u4e9a\u3001\u5317\u6b27\u7b49\u6d77\u5916\u5e02\u573a\uff0c2019\u5e741\u6708\uff0cMGI\u5ba3\u5e03\u7a81\u78341000\u53f0\uff0c\u76f4\u63a5\u5f71\u54cd\u5230Illumina Q1\u9500\u552e\u91cf\u3002\u540c\u65f6\uff0c\u4e5f\u8981\u770b\u5230\uff0c\u57fa\u4e8e\u7eb3\u7c73\u5b54\u6d4b\u5e8f\uff08\u4e09\u4ee3\u6d4b\u5e8f\uff09\u7684\u65b0\u516c\u53f8\u9646\u7eed\u8fdb\u573a\uff0c\u5305\u62ec\u5b89\u5e8f\u6e90\u3001\u9f50\u78b3\u79d1\u6280\u7b49\u3002\u701a\u6d77\u57fa\u56e0\u66f4\u540d\u4e3a\u771f\u8fc8\u751f\u7269\uff08GeneMind\uff09\u65d7\u4e0bGenoCare 1600\u5355\u5206\u5b50\u57fa\u56e0\u6d4b\u5e8f\u4eea\u57282\u6708\u901a\u8fc7\u533b\u7597\u5668\u68b0\u6ce8\u518c\u68c0\u9a8c\uff0c8\u6708\u6b63\u5f0f\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u9636\u6bb5\u3002\u800c\u88ab\u4f20\u53d7\u9080\u6536\u8d2d\u7684Oxford Nanopore\u4e0e\u5e0c\u671b\u7ec4\u5efa\u7acb\u6218\u7565\u8054\u76df\uff0c\u5e76\u53ef\u80fd\u5728\u56fd\u5185\u6df1\u5165\u6269\u5f20\uff0c\u4e0e\u4e8c\u4ee3\u6d4b\u5e8f\u6216\u5c06\u5c55\u5f00\u6b63\u9762\u7ade\u4e89\uff0c\u53ef\u4ee5\u63a8\u6d4b\u534e\u5927\u6ca1\u6709\u9009\u62e9\u5730\u5c06\u7814\u53d1\u6216\u6536\u8d2d\u4e09\u4ee3\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u3002\u4e0d\u53d8\u7684\u662f\uff0c\u672a\u6765\u7684\u57fa\u56e0\u4ea7\u4e1a\u5c06\u7531\u7c7b\u4f3c\u963f\u91cc\u5df4\u5df4\u8fd9\u6837\u4f53\u91cf\u7684\u51e0\u4e2a\u96c6\u56e2\u5206\u5ead\u6297\u793c\uff0c\u800c\u6d4b\u5e8f\u4eea\u7684\u5730\u4f4d\u5982\u540c\u652f\u4ed8\u5b9d\u3002\u8fd9\u5c06\u662f\u91cd\u8d44\u672c\u5e03\u5c40\u548c\u5934\u90e8\u4f01\u4e1a\u7ade\u4e89\u5c24\u4e3a\u5173\u952e\u7684\u90e8\u5206\uff1b\u53d8\u7684\u662f\uff0c\u5784\u65ad\u5c24\u4e3a\u5c1a\u65e9\uff0c\u5728\u5f53\u524d\u4e5f\u4e0d\u88ab\u5141\u8bb8\u3002\u9664\u4e86\u6d4b\u5e8f\u4eea\u5916\uff0c\u6570\u5b57PCR\u548c\u6838\u9178\u8d28\u8c31\u5c06\u4e0e\u4e4b\u4e92\u8865\uff08\u89c1\u4e0b\u6587\uff09\u3002\u800c\u5360\u636e\u8f83\u5927\u6210\u672c\u7684\u8bd5\u5242\u6d88\u8017\uff0c\u65e9\u5e74\u7684\u5934\u90e8\u4f01\u4e1a\u5784\u65ad\u6b63\u5728\u6253\u7834\uff0c\u4f8b\u5982\u5bf9\u6807Agilent\u7684\u827e\u5409\u6cf0\u5eb7\u548cBIOPTIC\uff08\u540e\u8005\u539a\u6cfd\u751f\u7269\u4ee3\u7406\uff09\u3002<\/div>\n
\u4e2d\u6e38\uff0c\u6838\u5fc3\u662f\u6570\u636e\u91c7\u96c6\u3001\u751f\u7269\u4fe1\u606f\u5206\u6790\u8f6f\u4ef6\u548c\u9057\u4f20\u54a8\u8be2\u89e3\u8bfb\u3002\u5404\u5927\u79d1\u6280\u6216\u4e34\u5e8a\u6d4b\u5e8f\u670d\u52a1\u516c\u53f8\u6240\u79f0\u7684\u6837\u672c\u4f18\u52bf\uff0c\u5b58\u5728\u7740\u70ed\u70b9\u75c5\u79cd\u540c\u8d28\u5316\u548c\u7f3a\u4e4f\u4e34\u5e8a\u8868\u578b\u4fe1\u606f\u4e24\u5927\u95ee\u9898\u3002\u8fd9\u70b9\u4e0a\uff0c\u4e00\u65b9\u9762\u6709IT\u80cc\u666f\u7684\u4f8b\u5982\u8363\u4e4b\u8054\u3001\u795e\u5dde\u533b\u7597\u7b49\u901a\u8fc7\u6295\u8d44\u7b49\u65b9\u5f0f\u8fdb\u573a\uff0c\u4f46\u65b9\u6848\u5c1a\u4e0d\u6210\u719f\uff1b\u53e6\u4e00\u65b9\u9762\u6709\u836f\u5382\u80cc\u666f\u7684\u4f8b\u5982\u4ec1\u4e1c\u533b\u5b66\u3001\u836f\u660e\u660e\u7801\u7b49\u53d1\u5c55\u8fc5\u901f\u3002\u672a\u6765\u8fd9\u7c7b\u6df7\u5408\u80cc\u666f\u7684\u516c\u53f8\u4f1a\u589e\u591a\uff0c\u4f8b\u5982\u5148\u58f0\u8bca\u65ad\u3001\u4f17\u5b89\u751f\u547d\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u751f\u7269\u4fe1\u606f\u5206\u6790\u8f6f\u4ef6\u65b9\u9762\uff0c\u8fd1\u5e74\u5c1a\u672a\u51fa\u73b0\u7c7b\u4f3cGATK\uff0cAnnovar\u7684\u4ee3\u8868\u8f6f\u4ef6\u3002\u76ee\u524d\u8fd9\u65b9\u9762\u53d1\u529b\u7684\u4e3b\u8981\u662fDNAnexus\uff0cSevenBridges\u7b49\u8001\u724c\u751f\u7269\u4fe1\u606f\u516c\u53f8\u4ee5\u53ca\u56fd\u5185\u7684\u963f\u91cc\u4e91\u3001\u534e\u4e3a\u4e91\u3001\u82f1\u7279\u5c14\u7b49\u4e91\u8ba1\u7b97\u53caIT\u516c\u53f8\uff0c\u5c1a\u672a\u53d7\u5230\u56fd\u5185\u4ea7\u4e1a\u91cd\u89c6\u3002\u4f46\u76d1\u7ba1\u9010\u6e10\u5bf9\u57fa\u56e0\u62a5\u544a\u73af\u8282\u52a0\u5f3a\u89c4\u8303\u540e\uff0c\u6d88\u8d39\u7ea7\u53ca\u4e34\u5e8a\u7ea7\u75be\u75c5\u9884\u6d4b\u5efa\u6a21\u4e0a\uff0c\u8f6f\u4ef6\u53ca\u57fa\u56e0\u4e91\u5e73\u53f0\u77e5\u8bc6\u4ea7\u6743\u8fd9\u5c06\u6210\u4e3a\u4f01\u4e1a\u6838\u5fc3\u7ade\u4e89\u529b\u4e4b\u4e00\uff0c\u7279\u522b\u662fGithub\u7b49\u5f00\u6e90\u793e\u533a\u88ab\u5b98\u65b9\u88f9\u631f\u540e\u3002\u7b14\u8005\u53c2\u4e0e\u8fc7\u56fd\u5185\u7b2c\u4e00\u4ee3\u57fa\u56e0\u4e91\u5e73\u53f0\u7684\u5f00\u53d1\uff0c\u6df1\u6709\u4f53\u4f1a\u3002<\/div>\n
\u5728\u9057\u4f20\u54a8\u8be2\u89e3\u8bfb\u4e0a\uff0c\u4eba\u624d\u532e\u4e4f\u662f\u8001\u751f\u5e38\u6001\uff0c\u56e0\u6b64\u662f\u76d1\u7ba1\u7684\u6700\u5927\u98ce\u9669\u70b9\uff0c\u51fa\u73b0\u90e8\u5206\u4e0d\u826f\u4f01\u4e1a\u6ca1\u6709\u68c0\u6d4b\u800c\u51fa\u62a5\u544a\u7684\u9690\u60a3\u3002\u76ee\u524d\u6c11\u95f4\u7684\u9057\u4f20\u54a8\u8be2\u57f9\u8bad\u73ed\u5bf9\u6b64\u8fdb\u884c\u4e86\u6709\u6548\u7684\u79d1\u666e\uff0c\u4f46\u62a5\u540d\u548c\u8003\u6838\u95e8\u69db\u8bbe\u7f6e\u4e0d\u9ad8\uff0c\u4ecd\u9700\u5b8c\u5584\u673a\u5236\uff0c\u4eca\u5e745\u6708\uff0c\u56fd\u5bb6\u536b\u5065\u59d4\u4e3b\u529e\u7684\u9057\u4f20\u54a8\u8be2\u80fd\u529b\u5efa\u8bbe\u4e13\u59d4\u4f1a\u6210\u7acb\uff0c<\/a>\u4e0d\u5c11\u4e13\u5bb6\u547c\u5401\u5efa\u7acb\u9057\u4f20\u54a8\u8be2\u76f8\u5173\u5b66\u79d1\u53ca\u4e13\u4e1a\u3002\u672a\u6765\uff0c\u7ed3\u5408\u66f4\u591a\u7684\u6570\u636e\u53ca\u77e5\u8bc6\u5e93\uff0c\u6570\u636e\u5206\u6790\u7ed3\u5408\u5927\u90e8\u5206\u7684\u9057\u4f20\u54a8\u8be2\u73af\u8282\u5c06\u5f62\u6210\u4e00\u4f53\u5316\u8f6f\u4ef6\u6216\u4e00\u4f53\u673a\uff0c\u867d\u7136\u8fd9\u662f\u5f88\u591a\u533b\u751f\u65e0\u6cd5\u63a5\u53d7\u7684\uff0c\u4f46\u53ea\u6709\u8fd9\u6837\u624d\u80fd\u6807\u51c6\u5316\u548c\u89c4\u6a21\u5316\uff0c\u800c\u4e13\u5bb6\u5728\u8f6f\u4ef6\u5efa\u8bbe\u4e0a\u4f5c\u4e3a\u6807\u51c6\u8f93\u5165\u8005\u548c\u53d7\u76ca\u8005\u3002<\/div>\n
\u00a0<\/div>\n
\u4e0b\u6e38\u7684\u5e94\u7528\u4e0a\uff0c\u76ee\u524d\u6210\u719f\u5e94\u7528\u4ec5\u5305\u62ecNIPT\u548cDNA\u53f8\u6cd5\u9274\u5b9a\uff0c\u4ea7\u54c1\u7814\u53d1\u548c\u8bbe\u8ba1\u4ecd\u9700\u52a0\u5927\u6295\u5165\u3002<\/div>\n
\u7edd\u5927\u90e8\u5206\u4f01\u4e1a\u4e13\u6ce8\u4e8e\u6253\u5f00\u5546\u4e1a\u6e20\u9053\u5916\uff0c\u66f4\u591a\u662f\u62a5\u8bc1\uff0c\u7279\u522b\u80bf\u7624Panel\uff0c\u8fd9\u4e2a\u9886\u57df\u8d70\u5728\u524d\u5217\u7684\u71c3\u77f3\u533b\u5b66\u5b8c\u6210C\u8f6e\u878d\u8d44\uff0c\u4e16\u548c\u57fa\u56e0\u5728\u7b79\u5907\u4e0a\u5e02\uff0c\u8bfa\u79be\u81f4\u6e90\u5df2\u4e8e\u53bb\u5e7412\u6708\u53d1\u5e03\u62db\u80a1\u8bf4\u660e\u4e66\uff08\u76ee\u524d\u5904\u4e8e\u9759\u9ed8\u671f\uff09\uff0c\u5409\u56e0\u52a0\u548c\u534e\u5927\u80bf\u7624\u7684\u62a5\u8bc1\u597d\u4e8b\u5c06\u8fd1\u3002\u5176\u706b\u70ed\u539f\u56e0\uff0c\u662f\u6b64\u7c7bPanel\u4ef7\u503c\u662f\u7528\u836f\u4f34\u968f\u8bca\u65ad\uff08\u7528\u836f\u6307\u5bfc\uff09\uff0c\u800c\u76f8\u5e94\u7684\u514d\u75ab\u6cbb\u7597\u836f\u7269\u65b0\u836f\u7814\u53d1\u52a0\u901f\uff08\u89c1\u4e0b\u6587\uff09\u3002\u540c\u65f6\uff0c\u6211\u4eec\u4e5f\u5e94\u6ce8\u610f\u5230\uff0c\u764c\u75c7\u65e9\u8bca\u53ca\u65e9\u7b5b\u4ecd\u5904\u4e8e\u98ce\u53e3\u7684\u4f30\u503c\uff0c\u7279\u5f02\u6027\u548c\u654f\u611f\u6027\u4ecd\u9700\u4f18\u5316\u3002<\/div>\n
\u5373\u4fbf\u5728\u6210\u719f\u7684NIPT\u8d5b\u9053\uff0c\u7eb5\u5411\u6280\u672f\u548c\u5e94\u7528\u4e0a\u4ecd\u6709\u62d3\u5c55\u7684\u7a7a\u95f4\u3002Illumina\u57282019\u5e748\u6708\u63a8\u51fa\u5168\u57fa\u56e0\u7ec4\u975e\u6574\u500d\u4f53\u7684\u7b2c\u4e8c\u4ee3NIPT\u4ea7\u54c1VeriSeq v2\uff0c\u4f18\u8fc5\u533b\u5b66\u548c\u8d1d\u745e\u57fa\u56e0\u7b49\u62d3\u5c55NIPT plus\uff0c\u534e\u5927\u5728\u5b55\u671f193\u4e07\u5b55\u5987\u65e0\u521b\u4ea7\u524d\u57fa\u56e0\u7b5b\u67e5\u53d1\u73b0\u5b55\u671f\u80bf\u7624<\/a>\uff0c\u7efc\u5408PPV\u4e3a75.0\uff05\uff0c\u6a2a\u5411\u7684\u5e02\u573a\u62d3\u5c55\u4e0a\uff0c\u4e00\u65b9\u9762\u534e\u5927\u5728\u6df1\u5733\u3001\u957f\u6c99\u4ee5\u53ca\u65e5\u524d\u7684\u6cb3\u5317\u7701\u4ee5\u5730\u65b9\u653f\u5e9c\u5408\u4f5c\u6a21\u5f0f\u5f62\u6210\u5c40\u90e8\u5784\u65ad\uff1b\u53e6\u4e00\u65b9\u9762\uff0c\u5e02\u573a\u7ade\u4e89\u9010\u6e10\u4e0b\u6c89\u5230\u4e8c\u4e09\u7ebf\u57ce\u5e02\u3002\u4f46\u957f\u671f\u800c\u8a00\uff0cB2G\u6a21\u5f0f\u6216\u7ec8\u5c06\u8d70\u5411B2C\u3002<\/div>\n
\u00a0<\/div>\n
\u6d88\u8d39\u7ea7\uff08DTC\uff09\u57fa\u56e0\u68c0\u6d4b\u65b9\u9762\uff0cIllumina\u57285\u6708\u5ba3\u5e03\u4e0d\u6301\u6709Helix\u4efb\u4f55\u6743\u5229\u540c\u65f6\u9000\u51fa\u8463\u4e8b\u4f1a\uff0c\u540e\u8005\u57282019\u5e74\u7b2c\u4e00\u5b63\u5ea6\u6536\u5165\u4ec5100\u4e07\u7f8e\u5143\uff0c\u4eceB2C\u8f6c\u53d8\u4e3a\u793e\u4f1a\/\u653f\u5e9c\u5408\u4f5c\u7684\u7fa4\u4f53\u57fa\u56e0\u7ec4\u9879\u76ee\uff0c\u7c7b\u4f3cGoogle Verily\u3002WeGene\u9664\u4e86\u7838\u94b1\u6295\u5165\u7efc\u827a\u8282\u76ee\u690d\u5165\u7b49\u6d41\u91cf\u5e7f\u544a\u5916\uff0c\u5efa\u8bbe\u4e34\u5e8a\u57fa\u56e0\u68c0\u6d4b\u5b9e\u9a8c\u5ba4\uff0c\u5e76\u548c\u591a\u5bb6\u79d1\u7814\u673a\u6784\u5c55\u5f00\u7fa4\u4f53\u57fa\u56e0\u7ec4\u9879\u76ee\uff0c\u4ea7\u54c1\u91cd\u70b9\u4e5f\u4ece\u82af\u7247\u8f6c\u5411WGS\uff0c\u4e0e\u6295\u8d44\u65b9\u534e\u5927\u5f62\u6210\u4e0a\u4e0b\u6e38\u7d27\u5bc6\u5408\u4f5c\u3002\u800c\u623f\u5730\u4ea7\u6570\u636e\u51fa\u8eab\u768423\u9b54\u65b9\u5ba3\u5e03\u201c\u96f6\u5143\u68c0\u6d4b\u201d\u670d\u52a1\uff0c\u70e7\u94b1\u6512\u6570\u636e\u548c\u54c1\u724c\uff0c\u5f62\u6210DTC\u9886\u57df\u7eb5\u5411\u548c\u6a2a\u5411\u4e24\u5927\u6218\u7565\uff0c\u5c1a\u4e0d\u5206\u80dc\u8d1f\u3002<\/div>\n
\u5176\u4ed6\u65b0\u8d5b\u9053\u89c1\u7b2c\u56db\u90e8\u5206\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u4e09\u00a0\u00a0 2019\u4e0a\u534a\u5e74\u7684\u57fa\u56e0\u884c\u4e1a\u6295\u878d\u8d44\u56fe\u8c31<\/div>\n
\u6295\u878d\u8d44\u6570\u636e\u662f\u6700\u6709\u529b\u7684\u4ea7\u4e1a\u53d1\u5c55\u7ebf\u7d22\u4e4b\u4e00\u3002\u8fd9\u91cc\uff0c\u57fa\u56e0\u6167\u4e00\u5982\u65e2\u5f80\u548c\u60a8\u5206\u4eab\u5e74\u4e2d\u6295\u878d\u8d44\u56fe\u8c31\uff08\u5f80\u5e74\u6295\u878d\u8d44\u5206\u6790\u89c1\u4e0b\u6587\u201c\u62d3\u5c55\u9605\u8bfb\u201d\u7684\u63a8\u8350\uff09\u3002<\/div>\n\n
\n
\"RmFicvQBAkgBficjBLfGo8EZV8DadhdzwPAw3pAFKs8qfvbLUuZs1DiaMwhkjFqRZJvnibN7nqkns4RjEk1VSGe3yQ\"\/<\/figure><\/div>\n\n<\/div>\n
\u56fe\uff1a2019\u5e741-6\u6708\u56fd\u5185\u5916\u57fa\u56e0\u884c\u4e1a\u6295\u878d\u8d44\u76d8\u70b9\uff08\u6765\u6e90\uff1a\u57fa\u56e0\u6167\uff09<\/div>\n
<\/div>\n
<\/div>\n\n
\n
\"RmFicvQBAkgADLaPh42HG7CRiaHZ7ZHntXfmcBgCPO788x0VVjlLkFkNt9F0iaLzvE27ezx6xEUdVgicNxWDaPCJCg\"\/<\/figure><\/div>\n\n
\u56fe\uff1a2019\u5e741-6\u6708\u56fd\u5185\u4e0e\u56fd\u5916\u57fa\u56e0\u884c\u4e1a\u6295\u878d\u8d44\u5bf9\u6bd4\uff08\u6765\u6e90\uff1a\u57fa\u56e0\u6167\uff09<\/div>\n
<\/div>\n
<\/div>\n
\u636e\u4e0d\u5b8c\u5168\u7edf\u8ba1\uff0c2019\u5e74\u4e0a\u534a\u5e74\u56fd\u5185\u5916\u57fa\u56e0\u884c\u4e1a\u5171\u8ba143\u8d77\u878d\u8d44\uff0c\u603b\u52df\u8d44\u7ea638\u4ebf\u7f8e\u5143\u3002\u5176\u4e2d\uff0c\u56fd\u518520\u8d77\u878d\u8d44\u4e8b\u4ef6\uff0c\u52df\u8d44\u91d1\u989d\u7ea66.56\u4ebf\u7f8e\u5143\uff1b\u56fd\u591623\u8d77\u878d\u8d44\u4e8b\u4ef6\uff0c\u52df\u8d44\u91d1\u989d\u7ea631.46\u4ebf\u7f8e\u5143\uff0c\u5360\u878d\u8d44\u603b\u989d83%\u3002\u56fd\u5916\u5355\u7b14\u878d\u8d44\u4e8b\u4ef6\u7684\u5e73\u5747\u91d1\u989d\u662f\u56fd\u5185\u56db\u500d\uff0c\u4e00\u65b9\u9762\u56fd\u5916\u878d\u8d44\u7565\u504f\u5411\u4e8e\u4e2d\u540e\u671f\uff08B\u8f6e\u53ca\u4ee5\u540e\u878d\u8d44\u4e8b\u4ef6\uff0c\u56fd\u5185\u4f01\u4e1a35%\uff0c\u56fd\u5916\u4f01\u4e1a50%\uff09\uff0c\u53e6\u4e00\u65b9\u9762\u57fa\u56e0\u7597\u6cd5\u9886\u57df\u63a5\u53d7\u5927\u91cf\u6ce8\u8d44\uff08\u89c1\u4e0b\u6587\u5206\u6790\uff09\u3002<\/div>\n
\n\n
\n
\"RmFicvQBAkgBficjBLfGo8EZV8DadhdzwPztNibdDhPbY4UbHL47FxB3cHKRGxNSaVyYz49XgAn9woAQ6UibMMSpPQ\"\/<\/figure><\/div>\n\n<\/div>\n
\u56fe\uff1a2018\u30012019\u5e74\u57fa\u56e0\u884c\u4e1a\u6295\u878d\u8d44\u70ed\u5ea6\u5bf9\u6bd4\uff08\u6765\u6e90\uff1a\u57fa\u56e0\u6167\uff09<\/div>\n
\u76f8\u8f832018\u5e74\u540c\u671f\uff0c\u878d\u8d44\u9891\u6b21\u51cf\u5c1151%\uff0c\u8d44\u672c\u56de\u5f52\u7406\u6027\u3002\u7d2b\u725b\u57fa\u91d1\u6295\u8d44\u603b\u76d1\u4fde\u6ce2\u63a5\u53d7\u57fa\u56e0\u6167\u91c7\u8bbf\u8868\u793a\uff0c\u76ee\u524d\u5bf9\u9879\u76ee\u7684\u5224\u65ad\u660e\u663e\u6bd4\u4e4b\u524d\u66f4\u8c28\u614e\uff0c\u4f1a\u66f4\u770b\u91cd\u56e2\u961f\u7684\u81ea\u6211\u9020\u8840\u80fd\u529b\u3001\u5177\u4f53\u573a\u666f\u7684\u843d\u5730\u80fd\u529b\u4ee5\u53ca\u521b\u59cb\u56e2\u961f\u7684\u683c\u5c40\u3002\u540c\u65f6GDP\u56de\u843d\u53ca\u53bb\u6760\u6746\u5e26\u6765\u52df\u8d44\u7684\u56f0\u96be\u4e5f\u662f\u5f71\u54cd\u56e0\u7d20\uff0c\u5728\u7ecf\u6d4e\u653f\u7b56\u65b9\u9762\u7684\u5f71\u54cd\u53ef\u4ee5\u9884\u89c1\u5373\u5c06\u626d\u8f6c\u3002<\/div>\n
\n\n
\n
\"RmFicvQBAkgADLaPh42HG7CRiaHZ7ZHntXNAuWWAwPl0Ev7oojCxn0WBnJrzocPn2GMaCIg0JfTd1mRicicMXLNicFw\"\/<\/figure><\/div>\n\n<\/div>\n
\u56fe\uff1a2019\u5e741-6\u6708\u57fa\u56e0\u884c\u4e1a\u6295\u878d\u8d44\u8d5b\u9053\u5206\u6790\uff08\u6765\u6e90\uff1a\u57fa\u56e0\u6167\uff09<\/div>\n
<\/div>\n
<\/div>\n
\u878d\u8d44\u7684\u70ed\u95e8\u8d5b\u9053\u5305\u62ec\u57fa\u56e0\u7f16\u8f91\/\u57fa\u56e0\u6cbb\u7597\u3001\u80bf\u7624\u57fa\u56e0\u7ec4\u548c\u79d1\u6280\u670d\u52a1\uff0c\u76f8\u6bd4\u56fd\u5185\u6295\u8d44\u673a\u6784\u66f4\u624e\u5806\u4e8e\u80bf\u7624\u57fa\u56e0\u7ec4\u548c\u79d1\u6280\u670d\u52a1\uff0c\u56fd\u5916\u6295\u8d44\u673a\u6784\u5df2\u63d0\u65e9\u5728\u57fa\u56e0\u7597\u6cd5\u9886\u57df\u5e03\u5c40\uff0c\u540c\u65f6\u8fd9\u4e5f\u8ddf\u56fd\u5185\u7f3a\u4e4f\u57fa\u56e0\u7597\u6cd5\u9886\u57df\u4f18\u8d28\u6807\u7684\u6302\u94a9\u3002<\/div>\n
\n\n
\n
\"RmFicvQBAkgADLaPh42HG7CRiaHZ7ZHntXPUFYQtqftG7hkyGwrkpzZLHRibgJNnHOcz0jAGN4GbVJABnQtBICHxA\"\/<\/figure><\/div>\n\n<\/div>\n
\u56fe\uff1a2019\u5e741-6\u6708\u57fa\u56e0\u884c\u4e1a\u6295\u878d\u8d44\u9636\u6bb5\u548c\u70ed\u5ea6\u5206\u6790\uff08\u6765\u6e90\uff1a\u57fa\u56e0\u6167\uff09<\/div>\n
<\/div>\n
<\/div>\n
\u878d\u8d44\u8f6e\u6b21\u96c6\u4e2d\u5728A\u8f6e\uff0833%\uff09\uff0c\u5176\u6b21\u662fB\u8f6e\uff0816%\uff09\uff0c\u4e0e2018\u5e74\u878d\u8d44\u8f6e\u6b21\u96c6\u4e2d\u7a0b\u5ea6\u5927\u4f53\u76f8\u5f53\u3002\u540c\u65f6\uff0cC\u8f6e\u53ca\u4ee5\u540e\u7684\u878d\u8d44\u8f6e\u6b21\u589e\u591a\uff0c\u8fd9\u4e9b\u4f01\u4e1a\u5927\u591a\u6210\u7acb\u65f6\u95f4\u8d85\u8fc75\u5e74\uff0c\u5982\u71c3\u77f3\u533b\u5b66\u3001\u82cf\u535a\u533b\u5b66\u300110X Genomics\uff0c\u65e9\u5148\u4e00\u6b65\u5b8c\u6210\u4e86\u539f\u59cb\u6280\u672f\u79ef\u7d2f\u548c\u6e20\u9053\u5efa\u8bbe\u3002\u6b64\u5916\uff0c\u5934\u90e8\u4f01\u4e1a\u5403\u4e0b\u5927\u624b\u7b14\u878d\u8d44\uff0c\u524d\u4e94\u5bb6\u878d\u8d44\u5360\u4e0a\u534a\u5e74\u603b\u878d\u8d44\u91d1\u989d\u8d8570%\uff0c\u5934\u90e8\u6548\u5e94\u8d8a\u6765\u8d8a\u660e\u663e\uff0c\u8d44\u672c\u51fa\u624b\u8c28\u614e\u7684\u540c\u65f6\u66f4\u4e50\u4e8e\u5927\u624b\u7b14\u62bc\u6ce8\u4f18\u8d28\u6807\u7684\uff0c\u52a0\u5267\u4f18\u80dc\u52a3\u6c70\u3002<\/div>\n
\n\n
\n
\"RmFicvQBAkgADLaPh42HG7CRiaHZ7ZHntXKMuRwwLraFtKdbg3KMFqZES51RU2qyj5ZPMJzlIkQJHBav2oSDdrjA\"\/<\/figure><\/div>\n\n
\u56fe\uff1a2019\u5e741-6\u6708\u5934\u90e8\u878d\u8d44\u4e8b\u4ef6\uff08\u6765\u6e90\uff1a\u57fa\u56e0\u6167\uff09<\/div>\n
\u4ece\u6295\u8d44\u9891\u6b21\u6765\u770b\uff0c\u5168\u7403\u8303\u56f4\u5185\u4e0a\u534a\u5e74IDG\u8d44\u672c\u3001Arch Venture Partners\u548c\u793c\u6765\u4e9a\u6d32\u57fa\u91d1\u51fa\u624b\u6700\u591a\uff0c\u5176\u6b21\u677e\u79be\u8d44\u672c\u3001\u541b\u8054\u8d44\u672c\u4e5f\u8f83\u4e3a\u6d3b\u8dc3\uff0c\u4e3b\u8981\u5173\u6ce8\u57fa\u56e0\u7597\u6cd5\u3001\u75be\u75c5\u65e9\u7b5b\u4e0e\u8bca\u65ad\u3001\u6d4b\u5e8f\u4eea\u5668\u7b49\uff0c\u62e5\u6709\u8f83\u9ad8\u6280\u672f\u58c1\u5792\u3002\u8fd9\u4e9b\u4f18\u79c0\u6807\u7684\u7684\u878d\u8d44\u9636\u6bb5\u5927\u591a\u8fdb\u5165A\u8f6e\u6216B\u8f6e\uff0c\u521b\u59cb\u56e2\u961f\u4ee5\u79d1\u5b66\u5bb6\u80cc\u666f\u5c45\u591a\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u56db\u00a0\u3001 \u65e7\u8fb9\u754c\u7684\u6253\u7834\uff0c\u65b0\u8d5b\u9053\u7684\u5d1b\u8d77<\/div>\n
\u57fa\u56e0\u4ea7\u4e1a\u6700\u6709\u610f\u601d\u7684\u5730\u65b9\uff0c\u662f\u4e00\u5207\u5c1a\u65e0\u5b9a\u5c40\u3002\u65e7\u8fb9\u754c\u5728\u6253\u7834\uff0c\u65b0\u8d5b\u9053\u5728\u5d1b\u8d77\u3002<\/div>\n
\u80bf\u7624\u57fa\u56e0\u7ec4\u9886\u57df\uff0c\u6839\u636e\u56fd\u5bb6\u836f\u76d1\u5c40\u7edf\u8ba1\uff0c2018\u5e74\u6211\u56fd\u5171\u6279\u51c648\u4e2a\u65b0\u836f\u4e0a\u5e02\uff0c\u4e0a\u5e02\u7684\u6297\u764c\u65b0\u836f\u6570\u91cf\u8fbe18\u4e2a\uff0c\u6bd42017\u5e74\u589e\u957f157%\uff0c\u5ba1\u6279\u65f6\u95f4\u7f29\u77ed\u4e86\u4e00\u534a\u3002\u56fd\u5185\u521b\u65b0\u836f\u7684\u53d1\u5c55\uff0c\u4e0a\u6587\u63d0\u5230\u7684\u56fd\u5185\u5934\u90e8\u80bf\u7624\u57fa\u56e0\u4f01\u4e1a\u624e\u5806\u80bf\u7624\u5c0fPanel\uff08\u4e00\u822c\u4e3a\u5341\u4e2a\u5de6\u53f3\u57fa\u56e0\u7ec4\u5408\uff09\u62a5\u8bc1\uff0c\u9664\u4e86\u6db2\u4f53\u6d3b\u68c0\u4e4b\u5916\uff0c\u5373\u4e0e\u65b0\u836f\u53d1\u5c55\u4ea6\u6b65\u4ea6\u8d8b\uff1a\u80bf\u7624\u9776\u5411\u836f\u63d0\u4f9b\u7528\u836f\u6307\u5bfc\uff08\u4f34\u968f\u8bca\u65ad\uff09\u3002\u540c\u65f6\uff0cFMI\u7684\u5927Panel\u5df2\u843d\u5730\u4e2d\u56fd\uff0c\u90e8\u5206\u4f01\u4e1a\u5df2\u5c06\u91cd\u70b9\u4ece\u4e34\u5e8a\u80bf\u7624\u8bca\u65ad\u5230\u5065\u5eb7\u4eba\u7fa4\u7684\u80bf\u7624\u5927Panel\uff08\u4e00\u822c\u4e3a\u6570\u5341\u4e2a\u5230\u767e\u4f59\u4e2a\u57fa\u56e0\u7ec4\u5408\uff09\u751a\u81f3\u5168\u57fa\u56e0\u7ec4\u7b5b\u67e5\uff0c\u5206\u522b\u662f\u4ece\u77ed\u671f\u7684\u5546\u4e1a\u6267\u884c\u7b56\u7565\u548c\u957f\u671f\u7684\u6280\u672f\u8f6c\u5316\u7b56\u7565\u3002<\/div>\n
\u00a0<\/div>\n
\u53e6\u4e00\u65b9\u9762\uff0c\u7ee7\u53bb\u5e7410\u6708\u88d5\u7b56\u751f\u7269\u5b8c\u6210IDG\u9886\u6295\u7684\u6570\u4ebf\u5143B\u8f6e\u878d\u8d44\u540e\uff0c\u534e\u5927\u96c6\u56e2\u65d7\u4e0b\u7684\u6b66\u6c49\u534e\u5927\u5409\u8bfa\u56e03\u6708\u83b7\u5f971.2\u4ebf\u5143A\u8f6e\u6295\u8d44\uff0c6\u6708Adaptive Biotechnologies\u542f\u52a8IPO\u5e76\u52df\u8d442.3\u4ebf\u7f8e\u5143\u3002\u4ed6\u4eec\u7684\u8d5b\u9053\u662f\u514d\u75ab\u6d4b\u5e8f\u3002\u5373\u57fa\u4e8e\u80bf\u7624\u57fa\u56e0\u7ec4\u548c\u5fae\u751f\u7269\u7ec4\u7b49\uff0c\u5e2e\u52a9\u80bf\u7624\u60a3\u8005\u9009\u62e9\u6700\u9002\u5408\u7684\u6cbb\u7597\u65b9\u6848\u3002\u8fd9\u53ea\u662f\u80bf\u7624\u7528\u836f\u4f34\u968f\u8bca\u65ad\u7684\u5206\u652f\uff0c\u4f46\u53ef\u4e0e\u5236\u836f\u66f4\u5bc6\u5207\u7ed3\u5408\u3002\u4e0e\u4e4b\u5bf9\u5e94\u7684\u5e02\u573a\u73af\u5883\u662f\uff0c\u5305\u62ec\u541b\u5b9e\u751f\u7269\u3001\u4fe1\u8fbe\u751f\u7269\u3001\u6052\u745e\u5728\u5185\u7684\u4e09\u5bb6\u836f\u4f01\u7684\u56fd\u4ea7PD-L1\u5355\u6297\u5728\u6700\u8fd1\u4e24\u5e74\u4e0a\u5e02\uff0cBMS\u65d7\u4e0bPD-1\u6297\u4f53\u836fOpdivo\u57282018\u5e74\u5b9e\u73b067.35\u4ebf\u7f8e\u5143\u8425\u6536\uff0c\u540c\u6bd4\u589e\u957f36%\u30021\u6708BMS\u66f4\u662f\u9ad8\u8fbe740\u4ebf\u7f8e\u5143\u6536\u8d2dCAR-T\u514d\u75ab\u6cbb\u7597\u4f01\u4e1aCelgene\u3002\u56fd\u5185\u7684\u514d\u75ab\u6cbb\u7597\u660e\u661f\u4f01\u4e1a\u827a\u5999\u795e\u5dde\u4e5f\u5b8c\u62101.4\u4ebf\u5143\u4eba\u6c11\u5e01C\u8f6e\u878d\u8d44\uff0c\u836f\u660e\u5eb7\u5fb7\u548cJuno Therapeutics\u5728\u4e0a\u6d77\u5408\u8d44\u6210\u7acb\u836f\u660e\u5de8\u8bfa\u5728\u53bb\u5e746\u6708\u83b7\u5f97\u56fd\u5185\u9996\u5f20CD19 CAR-T\u4e34\u5e8a\u6279\u4ef6\u3002<\/div>\n
\u9664\u4e86\u5c0fPanel\u548c\u5927Panel\u7684\u4e34\u5e8a\u4f34\u968f\u8bca\u65ad\uff0c\u5065\u5eb7\u4eba\u7fa4\u7b5b\u67e5\u4e4b\u5916\uff0c\u7ee7\u65b0\u836fKeytruda\u548cVitrakvi\u4e4b\u540e\uff0c\u4eca\u5e748\u6708FDA\u6279\u51c6\u4e86\u7b2c\u4e09\u6b3e\u201c\u4e0d\u9650\u764c\u79cd\u201d\u7684\u6297\u764c\u7597\u6cd5Rozlytrek\uff0c\u4ee5\u9776\u5411\u9a71\u52a8\u764c\u75c7\u7684\u7279\u5b9a\u57fa\u56e0\u7279\u5f81\uff0c\u800c\u4e0d\u662f\u80bf\u7624\u8d77\u6e90\u7684\u7ec4\u7ec7\u7c7b\u578b\u3002\u8fd9\u4e0d\u4ec5\u5c06\u91cd\u65b0\u5b9a\u4e49\u75be\u75c5\u8bca\u65ad\u5206\u7ec4\uff0c\u4e5f\u4f1a\u5bf9\u65b0\u836f\u7814\u53d1\u53ca\u76f8\u5e94\u57fa\u56e0\u6807\u8bb0\u7269\u6316\u6398\u5e26\u6765\u65b0\u7684\u601d\u8def\uff0c\u5f53\u8fd9\u62e8\u6f6e\u6d41\u4f20\u9012\u5230\u56fd\u5185\u836f\u4f01\uff0c\u65b0\u7684\u6280\u672f\u548c\u8d5b\u9053\u53c8\u5c06\u8d77\u6d6a\u3002<\/div>\n
\u00a0<\/div>\n
\u5728DTC\u57fa\u56e0\u68c0\u6d4b\u9886\u57df\uff0cIllumina\u9000\u51faHelix\u8463\u4e8b\u4f1a\u5e2d\u4f4d\u540c\u65f6\uff0c\u4ee5\u7956\u6e90\u4e3a\u4e3b\u8981\u670d\u52a1\u7684\u7f8e\u56fd\u7b2c\u4e09\u5927\u4e2a\u4eba\u57fa\u56e0\u7ec4\u516c\u53f8MyHeritage\u63a8\u51fa\u4e86199\u7f8e\u5143\u7684\u5065\u5eb7\u57fa\u56e0\u68c0\u6d4b\u9879\u76ee\u3002\u56fd\u5185\uff0c4\u6708\u8d1d\u745e\u57fa\u56e0(SZ.000710)\u4e0e\u963f\u91cc\u5df4\u5df4\u9886\u62952.8\u4ebf\u5143\u7684\u9999\u6e2f\u516c\u53f8Prenetics\u6210\u7acb\u5706\u57fa\u56e0\uff0c\u5c06\u524d\u8c37\u6b4c\u4e2d\u56fd\u3001\u77e5\u540d\u5962\u4f88\u54c1\u4f01\u4e1aLVMH\u96c6\u56e2\u4ee5\u53ca\u524d23\u9b54\u65b9\u7684\u9ad8\u7ba1\u62db\u5165\u9ebe\u4e0b\u3002\u901a\u8fc7\u6d41\u91cf\u660e\u661f\u7ad9\u53f0\uff0c\u5c55\u5f00\u4f20\u7edf\u5feb\u6d88\u54c1\u7684\u63a8\u5e7f\u6253\u6cd5\uff0c\u572823\u9b54\u65b9\u4e4b\u540e\u5c55\u5f00\u540c\u6837\u7684\u201c0\u5143\u68c0\u6d4b\u201d\u670d\u52a1\u3002\u5355\u4eceDTC\u57fa\u56e0\u68c0\u6d4b\u4e00\u4e2a\u9886\u57df\uff0c\u4e0b\u6e38\u589e\u503c\u670d\u52a1\u4ecd\u5728\u5f97\u5230\u6ee1\u8db3\uff0c\u4ecd\u7f3a\u4e4f\u7206\u6b3e\u53ca\u5145\u5206\u9020\u8840\u529f\u80fd\uff0c\u4f7f\u5f97\u90e8\u5206\u8d44\u672c\u9000\u573a\uff0c\u540c\u65f6\u65b0\u8d44\u672c\u5165\u573a\u8bd5\u56fe\u5efa\u7acb\u54c1\u724c\u548c\u8679\u5438\u6570\u636e\u7684\u58c1\u5792\u3002<\/div>\n
\u00a0<\/div>\n
\u57fa\u56e0\u7f16\u8f91\u65b9\u9762\uff0c2018\u5e74\u5e95\u7684\u80da\u80ce\u57fa\u56e0\u7f16\u8f91\u4e8b\u4ef6\u52a0\u901f\u6b27\u7f8e\u4ee5\u53ca\u6211\u56fd\u52a0\u5f3a\u76d1\u7ba1\u89c4\u8303\u3002\u4e0e\u6b64\u540c\u65f6\u975e\u80da\u80ce\u57fa\u56e0\u7f16\u8f91\u5f97\u5230\u5feb\u901f\u8fed\u4ee3\u3002Editas\u7ee71\u6708CRISPR\/Cas9\u57fa\u56e0\u7597\u6cd5EDIT-101\u6210\u529f\u6062\u590d\u4e86Leber\u5148\u5929\u6027\u9ed1\u8499\u75c710\u578b\u7684\u89c6\u529b\u540e\uff0c\u516d\u4e2a\u6708\u540e\u542f\u52a8\u4e16\u754c\u9996\u4f8b\u4f53\u5185CRISPR\u57fa\u56e0\u7f16\u8f91\u4e34\u5e8a\u8bd5\u9a8c\u3002\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u548c\u51ef\u514b\u7814\u7a76\u6240\uff08KGI\uff09\u6210\u529f\u7814\u53d1\u51fa\u9996\u6b3e\u624b\u6301\u5f0fCRISPR\u82af\u7247\u751f\u7269\u4f20\u5bfc\u5668\u8bbe\u5907\uff0c\u6709\u671b\u6210\u4e3a\u5728\u5bb6\u81ea\u884c\u68c0\u6d4b\u81f4\u75c5\u7a81\u53d8\u7684\u624b\u6301\u5f0f\u8bbe\u5907\u3002\u4e39\u9ea6\u54e5\u672c\u54c8\u6839\u7684SNIPR Biome\u57fa\u4e8e\u57fa\u56e0\u7f16\u8f91\u5e72\u6270\u5fae\u751f\u7269\u7684\u6280\u672f\u7814\u53d1\u521b\u65b0\u836f\u3002\u56fd\u5185\u57fa\u56e0\u7f16\u8f91\u535a\u96c5\u8f91\u56e0\u548c\u542f\u51fd\u751f\u7269\u5747\u83b7\u5f97\u6d77\u5185\u5916\u6295\u8d44\u4eba\u9752\u7750\u3002<\/div>\n
\u00a0<\/div>\n
\u5bf9\u4e8e\u6295\u8d44\u4eba\u8fd1\u5e74\u70ed\u8877\u7684\u57fa\u56e0\u6cbb\u7597\uff0c\u4e25\u683c\u4e0a\u662f\u4e00\u4e2a\u96c6\u5408\u6982\u5ff5\uff0c\u5305\u62ec\u4e86\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u3001\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u7b49\uff0c\u4e5f\u6db5\u76d6\u90e8\u5206\u5b64\u513f\u836f\u3002\u518d\u751f\u533b\u5b66\u8054\u76df\uff08ARM\uff09\u53d1\u5e03\u76842019\u5e74\u7b2c\u4e00\u5b63\u5ea6\u518d\u751f\u533b\u5b66\u5168\u7403\u6570\u636e\u62a5\u544a\u663e\u793a\uff0c\u622a\u6b62\u7b2c\u4e00\u5b63\u5ea6\u672b\uff0c\u5168\u7403\u6709372\u9879\u57fa\u56e0\u6cbb\u7597\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5728\u8fdb\u884c\u4e2d\uff0c\u540c\u6bd4\u589e\u957f\u4e8617\uff05\u3002\u5176\u4e2d\uff0c58\uff05\u4e34\u5e8a\u8bd5\u9a8c\u5728\u2161\u671f\u9636\u6bb5\uff0c\u8fd1\u5e74\u5404\u5927\u836f\u4f01\u901a\u8fc7\u5408\u4f5c\u3001\u6536\u8d2d\u6216\u6295\u8d44\u7b49\u5f62\u5f0f\u5e03\u5c40\u57fa\u56e0\u6cbb\u7597\uff08\u89c1\u4e0b\u8868\uff09\u3002<\/div>\n\n
\n
\"RmFicvQBAkgADLaPh42HG7CRiaHZ7ZHntXQ0UD3rG1G6RFlUDb8TRicglSjDlEG678rIJWl7u1DhJ0cu7gqOwy9NA\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u836f\u4f01\u5e03\u5c40\u57fa\u56e0\u6cbb\u7597\u4e8b\u4ef6\u7684\u90e8\u5206\u7edf\u8ba1\uff08\u6765\u6e90\uff1a\u57fa\u56e0\u6167\uff09<\/div>\n
\u00a0<\/div>\n
\u7ee7Bluebird\u57fa\u56e0\u7597\u6cd5ZYNTEGLO\uff08\u6cbb\u7597\u03b2\u5730\u4e2d\u6d77\u8d2b\u8840\uff09\u3001\u8bfa\u534e\u65d7\u4e0b\u7684\u57fa\u56e0\u7597\u6cd5Zolgensma\uff08\u6cbb\u7597SMA\uff09\u83b7\u6279\u4e0a\u5e02\u540e\uff0c7\u6708\uff0cDicerna Pharmaceuticals\u7684\u5728\u7814RNAi\u7597\u6cd5DCR-PHXC\u83b7FDA\u6279\u51c6\u4e3a\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\uff0c\u7528\u4e8e\u6cbb\u75971\u578b\u539f\u53d1\u6027\u9ad8\u8349\u9178\u5c3f\u75c7\uff08PH1\uff09\u3002\u6211\u56fd\u56fd\u5bb6\u836f\u5178\u59d4\u5458\u4f1a\u516c\u5e03\u4e86\u300a\u5173\u4e8e\u4eba\u7528\u57fa\u56e0\u6cbb\u7597\u5236\u54c1\u603b\u8bba\u8349\u6848\u7684\u516c\u793a\u300b\uff0c\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u91d1\u5c71\u533b\u9662\u3001\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u4e2d\u5c71\u533b\u9662\u8054\u5408\u534e\u5927\u96c6\u56e2\u6210\u7acb\u80bf\u7624\u57fa\u56e0\u8bca\u65ad\u4e0e\u751f\u7269\u6cbb\u7597\u4e2d\u5fc3\uff0c\u56fd\u5185\u76f8\u5173\u4f01\u4e1a\u5305\u62ec\u82cf\u5dde\u5de5\u4e1a\u56ed\u533a\u7684\u5723\u8bfa\u751f\u7269\uff08\u5f00\u53d1RNAi\u5bfc\u5165\u6280\u672f\u7684\u6838\u9178\u65b0\u836f\uff09\u548c\u4e0a\u6d77\u5f20\u6c5f\u9ad8\u79d1\u56ed\u533a\u7684\u65af\u5fae\u751f\u7269\uff08\u5f00\u53d1mRNA\u75ab\u82d7\uff09\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u9664\u4e86\u4ee5\u4e0a\u88ab\u8bfb\u8005\u719f\u77e5\u7684\u8d5b\u9053\u5916\uff0c\u53d1\u5c55\u65f6\u95f4\u4ec5\u6b21\u4e8e\u79d1\u6280\u670d\u52a1\u7684DNA\u53f8\u6cd5\u9274\u5b9a\u5e38\u88ab\u5ffd\u7565\u3002\u534e\u5927\u65d7\u4e0b\u7684\u534e\u5927\u53f8\u6cd5\u5e74\u6536\u5165\u6709\u671b\u8fbe\u52301\u4ebf\u5143\u4eba\u6c11\u5e01\uff0c\u66f4\u662f\u8f6f\u690d\u5165\u7535\u89c6\u5267\u300a\u8001\u7537\u5b69\u300b\u4e2d\u3002\u82cf\u535a\u80a1\u4efd\u5b8c\u62105000\u4e07\u5143\u4eba\u6c11\u5e01C1\u8f6e\u878d\u8d44\u3002\u5728\u6280\u672f\u4e0a\uff0cDNA\u5206\u8fa8\u4eba\u8138\u7814\u7a76<\/a>\u591a\u5e74\u6765\uff0c\u52a0\u5165\u6027\u522b\u3001BMI\u3001\u5e74\u9f84\u7b49\u5efa\u6a21\u540e\uff0c\u5bf9\u4eba\u9762\u90e8\u8bc6\u522b\u7684\u521d\u6b65\u51c6\u786e\u7387\u5206\u522b\u53ef\u8fbe\u523083\uff05\u3002\u672a\u6765\u53ef\u4ee5\u9884\u89c1DNA\u8eab\u4efd\u6570\u636e\u5e93\u53ca\u8eab\u4efd\u8bc1\u6709\u671b\u666e\u53ca\u3002<\/div>\n
\u00a0<\/div>\n
\u5728\u79d1\u6280\u670d\u52a1\u9886\u57df\uff0c\u5355\u7ec6\u80de\u6d4b\u5e8f\u6b63\u5d2d\u9732\u5934\u89d2\uff0c\u65b0\u683c\u5143\u83b7\u8fd1\u4ebf\u5143Pre-A\u8f6e\u878d\u8d44\uff0c\u5317\u4eac\u5927\u5b66\u7684\u5f20\u6cfd\u6c11\u6559\u6388\u521b\u7acb\u767e\u5965\u667a\u6c47\u5b8c\u6210IDG\u8d44\u672c\u7684A\u8f6e\u878d\u8d44\u3002<\/div>\n
\u800c\u4f5c\u4e3a\u534e\u5927\u4e09\u5927\u6218\u7565\u65b9\u5411\u4e4b\u4e00\u7684\u4f20\u67d3\u75c5\u57fa\u56e0\u68c0\u6d4b\uff0c\u4e5f\u5438\u5f15\u4e86\u524d\u8bfa\u79be\u81f4\u6e90\u8054\u5408\u521b\u59cb\u4eba\u848b\u667a\u548c\u8d1d\u745e\u57fa\u56e0\u521b\u59cb\u56e2\u961f\u4e4b\u4e00\u738b\u73fa\uff0c\u4ed6\u4eec\u5206\u522b\u521b\u7acb\u4e86\u91d1\u5319\u57fa\u56e0\u548c\u6770\u6bc5\u751f\u7269\uff0c\u4e13\u6ce8\u4f20\u67d3\u75c5\u57fa\u56e0\u68c0\u6d4b\u3002\u76f8\u6bd4\u4f20\u7edf\u7684\u57f9\u517b\u6cd5\u3001PCR\u3001\u8d28\u8c31\u7b49\u65b9\u6cd5\uff0c\u57fa\u56e0\u68c0\u6d4b\u5927\u5927\u63d0\u9ad8\u4e86\u654f\u611f\u6027\u548c\u901a\u91cf\uff0c\u7279\u522b\u662f\u672a\u77e5\u75c5\u539f\u8bca\u65ad\uff0c\u800c\u4e14\u7f29\u77ed\u68c0\u6d4b\u65f6\u95f4\u3002\u6838\u5fc3\u95ee\u9898\u51c6\u786e\u5ea6\u5f88\u5927\u7a0b\u5ea6\u53d6\u51b3\u4e8e\u5206\u6790\u7684\u53c2\u8003\u6570\u636e\u5e93\u7684\u8303\u56f4\u548c\u5b8c\u6574\u6027\u3002\u8fd9\u4e2a\u65b9\u5411\u6781\u6709\u53ef\u80fd\u6211\u56fd\u5411\u201c\u4e00\u5e26\u4e00\u8def\u201d\u56fd\u5bb6\u8f93\u51fa\u7684\u516c\u5171\u536b\u751f\u5e94\u7528\u4e4b\u4e00\uff0c\u57fa\u56e0\u6167\u53d7\u9080\u53c2\u4e0e\u9632\u57ce\u6e2f\u5e02\u56fd\u9645\u533b\u5b66\u8bd5\u9a8c\u5408\u4f5c\u533a\u89c4\u5212\u8ba8\u8bba\u65f6\u91cd\u70b9\u63d0\u51fa\u4e86\u6b64\u6784\u60f3\u3002<\/div>\n
\u9664\u4e86\u4ee5\u4e0a\u76f8\u5bf9\u6210\u719f\u5e94\u7528\u8d5b\u9053\u5916\uff0c\u8fd8\u6709\u4e24\u4e2a\u524d\u6cbf\u65b9\u5411\u503c\u5f97\u65e9\u671f\u6295\u5165\uff0c\u5373\u57fa\u56e0\u5408\u6210\u548cDNA\u5b58\u50a8\u3002\u201c\u5408\u6210\u751f\u7269\u5b66\u201d\u8fde\u7eed\u4e24\u5e74\u4f5c\u4e3a\u6211\u56fd\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\uff0c\u6bcf\u5e74\u6295\u5165\u8fd110\u4ebf\u5143\u8fdb\u884c\u57fa\u7840\u7814\u7a76\uff0c\u57fa\u56e0\u5408\u6210\u662f\u5176\u4e2d\u524d\u6cbf\u65b9\u5411\u3002\u4ea7\u4e1a\u4e0aGreenlight Biosciences\u83b7\u5f97E\u8f6e\u6295\u8d445000\u4e07\u7f8e\u5143\uff0c\u5229\u7528\u6b7b\u7ec6\u80de\u7684\u9176\u751f\u4ea7\u53cc\u94feRNA\uff08dsRNA\uff09\u6765\u6e05\u9664\u519c\u4f5c\u7269\u75c5\u866b\u5bb3\uff1b\u6234\u4fca\u5f6a\u535a\u58eb\u521b\u7acb\u7684\u9752\u5170\u751f\u7269\u6210\u4e3a\u534e\u5927\u96c6\u56e2\u6536\u8d2d\u7684\u9996\u6279\u4f01\u4e1a\u4e4b\u4e00\u3002\u5728DNA\u5b58\u50a8\u65b9\u9762\uff0c3\u6708\uff0c\u5fae\u8f6f\u4e0e\u534e\u76db\u987f\u5927\u5b66\u65d7\u4e0b\u516c\u53f8\u5408\u4f5c\uff0c\u6210\u529f\u901a\u8fc7\u81ea\u52a8\u5316\u8bbe\u5907\u5c06\u6570\u5b57\u4fe1\u606f\u5b58\u50a8\u4e3aDNA\u5e76\u53ef\u8bfb\u53d6\u3002\u4e00\u4e2a\u6708\u540e\u534e\u4e3a\u5ba3\u5e03\u5c06DNA\u5b58\u50a8\u4f5c\u4e3a\u65b0\u6210\u7acb\u7684\u6218\u7565\u7814\u7a76\u9662\u7684\u91cd\u8981\u65b9\u5411\u4e4b\u4e00\u3002\u76ee\u524d\u8fd9\u4e24\u65b9\u9762\uff0c\u56fd\u5185\u4ea7\u4e1a\u5316\u51e0\u4e4e\u4e3a\u7a7a\u767d\uff0c\u4f46\u5df2\u53d7\u5230\u5173\u6ce8\u3002<\/div>\n
\u00a0<\/div>\n
\u9664\u4e86\u884c\u4e1a\u5185\u4e0d\u540c\u5e94\u7528\u53d1\u5c55\u5916\uff0c\u201c\u57fa\u56e0+\u201d\u7684\u8de8\u754c\u878d\u5408\u4e00\u76f4\u662f\u57fa\u56e0\u6167\u7814\u7a76\u7684\u91cd\u70b9\u3002\u6bd4\u5982\u5728\u201c\u57fa\u56e0+\u4fdd\u9669\u201d\u9886\u57df\uff0c\u7ee7\u534e\u5927\u3001\u8fbe\u5b89\u57fa\u56e0\u7b49\u5408\u4f5c\u9488\u5bf9\u5047\u9634\u6027\u68c0\u6d4b\u7ed3\u679c\u7684\u201c\u57fa\u56e0\u68c0\u6d4b+\u4fdd\u9669\u201d\u6a21\u5f0f\u540e\uff0c\u81f3\u672c\u533b\u7597\u3001\u81fb\u548c\u79d1\u6280\u63a8\u51fa\u57fa\u4e8e\u201c\u57fa\u56e0\u4f34\u968f\u8bca\u65ad+\u7528\u836f\u9669\u201d\u7ed3\u5408\u3002\u5728\u201c\u57fa\u56e0+\u65b0\u836f\u201d\u9886\u57df\uff0c\u9664\u4e86\u4ee5\u4e0a\u7684\u514d\u75ab\u6cbb\u7597\u3001\u57fa\u56e0\u7f16\u8f91\u4e4b\u5916\uff0c\u7f55\u89c1\u75c5\u4f5c\u4e3a\u590d\u6742\u751f\u547d\u7684\u9057\u4f20\u7ebf\u7d22\u7814\u7a76\u5bf9\u8c61\uff0c\u6210\u4e3a\u5b64\u513f\u836f\u4ee5\u53ca\u5e38\u89c1\u75be\u75c5\u65b0\u836f\u7684\u7814\u53d1\u8def\u5f84\u4e4b\u4e00\u3002\u800c\u201c\u57fa\u56e0\u6570\u636e+\u4e34\u5e8a\u8868\u578b\u6570\u636e\u201d\u7684\u751f\u547d\u6570\u5b57\u5316\u4e0d\u7528\u8d58\u8ff0\uff0c\u65e0\u8bba\u4ece\u817e\u8baf\u91cd\u91d1\u6295\u8d44\u7684\u78b3\u4e91\u667a\u80fd\uff0c\u9a6c\u4e91\u5148\u540e\u4e0e\u674e\u9769\u3001\u738b\u4e9a\u4e1c\u6559\u6388\u7684\u4f1a\u9762\uff0c\u8fd8\u662f\u767e\u5ea6\u98ce\u6295\u9891\u9891\u5165\u5c40\u57fa\u56e0\u4f01\u4e1a\u53ca\u5a92\u4f53\uff0c\u4ee5\u53ca\u963f\u91cc\u3001\u534e\u4e3a\u3001\u82f1\u70ed\u5c14\u3001IBM\u3001Google\u7b49\u4f01\u4e1a\u4e91\u8ba1\u7b97\u90e8\u95e8\u4e0e\u57fa\u56e0\u516c\u53f8\u7684\u7d27\u5bc6\u5408\u4f5c\uff0c\u53ef\u4ee5\u9884\u89c1\u5728\u6570\u636e\u79ef\u7d2f\u7684\u8282\u70b9\uff0c\u5c06\u548c\u533b\u7597\u53ca\u5065\u5eb7\u4eba\u5de5\u667a\u80fd\u4ea7\u751f\u6307\u6570\u7ea7\u7684\u5316\u5b66\u53cd\u5e94\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u4e94\u00a0\u3001\u5e76\u8d2d\u6d45\u6790<\/div>\n
\u6211\u4eec\u77e5\u9053\uff0cIllumina\u901a\u8fc72017\u5e74\u5e76\u8d2dSolexa\u5b8c\u6210\u534e\u4e3d\u8f6c\u8eab\uff0c\u534e\u5927\u901a\u8fc72013\u5e74\u5b8c\u6210\u6536\u8d2dComplete Genomics\u6253\u7834\u751f\u4ea7\u74f6\u9888\u5e76\u915d\u917f\u4e0b\u4e00\u4e2a\u4e0a\u5e02\u516c\u53f8\uff0c\u800cThermo Fisher\u7b49\u516c\u53f8\u7684\u53d1\u5c55\u66f4\u662f\u4f34\u968f\u7740\u5e76\u8d2d\uff08\u89c1\u4e0b\u56fe\uff09\u3002<\/div>\n\n
\n
\"RmFicvQBAkgADLaPh42HG7CRiaHZ7ZHntXQOTwOv8xKXBqVMabF5UnliaWsCmq3HoFWNjwU8iamfravaX11ia8H2ezQ\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u77e5\u540d\u57fa\u56e0\u4f01\u4e1a\u7684\u5e76\u8d2d\u53ca\u53d1\u5c55\u8282\u70b9\uff08\u6765\u6e90\uff1a\u57fa\u56e0\u6167\uff09<\/div>\n
\u8fd1\u671f\u7684\u5e76\u8d2d\u96c6\u4e2d\u5728\u57fa\u56e0\u7597\u6cd5\u548c\u80bf\u7624\u57fa\u56e0\u4e24\u5927\u9886\u57df\uff0c\u4e2d\u56fd\u751f\u7269\u79d1\u6280\u670d\u52a1\u63a7\u80a1\u6709\u9650\u516c\u53f8(08037)\u6536\u8d2d\u4e2d\u79d1\u666e\u745e\uff0cBiogen $8.77\u4ebf\u6536\u8d2d\u57fa\u56e0\u7597\u6cd5\u516c\u53f8Nightstar\uff0c\u5f53\u7f57\u6c0f\u8868\u793a\u8ba1\u5212\u4ee548\u4ebf\u7f8e\u5143\u6536\u8d2dSpark Therapeutics\u65f6\u3002\u8d5b\u9ed8\u98de\u4e16\u5c14\u8868\u793a\u5c06\u4ee517\u4ebf\u7f8e\u5143\u6536\u8d2d\u57fa\u56e0\u6cbb\u7597\u516c\u53f8Brammer Bio\uff0cExact Sciences\u548cGenomic Health\u4ee528\u4ebf\u7f8e\u5143\u91d1\u989d\u5408\u4e3a\u65b0\u7684\u764c\u75c7\u8bca\u65ad\u516c\u53f8\u3002<\/div>\n
\u57fa\u56e0\u6167\u83b7\u6089\uff0c\u9664\u4e86\u4e0a\u6587\u63d0\u5230\uff0c\u534e\u5927\u96c6\u56e2\u53ef\u80fd\u8c0b\u6c42\u5411\u5916\u6536\u8d2d\uff0c\u540c\u65f6\u56fd\u5916\u5305\u62ec\u8bbe\u5907\u751f\u4ea7\u4f01\u4e1a\u3001\u6210\u719f\u8d5b\u9053\u670d\u52a1\u4f01\u4e1a\u4e5f\u6709\u610f\u6536\u8d2d\u56fd\u5185\u57fa\u56e0\u6570\u636e\u4f01\u4e1a\uff0c\u4ece\u800c\u5b8c\u6210\u5e02\u573a\u7684\u4e92\u8865\u3002<\/div>\n
\u00a0<\/div>\n
\u5728\u5e76\u8d2d\u65b9\u5411\u4e0a\uff0c\u7d2b\u725b\u57fa\u91d1\u6295\u8d44\u603b\u76d1\u4fde\u6ce2\u8868\u793a\uff0c\u66f4\u770b\u597d\u6e20\u9053\u6027\u516c\u53f8\u4e0e\u4ea7\u54c1\u516c\u53f8\u7684\u5e76\u8d2d\uff0c\u4e24\u8005\u58c1\u5792\u90fd\u4e0d\u6613\u88ab\u8f7b\u6613\u653b\u7834\u66ff\u6362\uff0c\u4e24\u8005\u6210\u529f\u6574\u5408\u5e76\u8d2d\u4e0b\u6e20\u9053\u7684\u5171\u6709\u6027\u4ee5\u53ca\u4ea7\u54c1\u7684\u6a2a\u5411\u62d3\u5c55\u4f1a\u7a81\u7834\u539f\u6709\u7684\u5929\u82b1\u677f\u9650\u5236\u3002<\/div>\n
\u66f4\u591a\u5e76\u8d2d\u903b\u8f91\u5206\u6790\u8bf7\u89c1\u57fa\u56e0\u6167\u540e\u7eed\u62a5\u9053\u7684\u5e74\u4e2d\u76d8\u70b9\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u516d\u3001\u4e0a\u5e02\u4f01\u4e1a\u6570\u636e\u6d45\u6790<\/div>\n\n
\n
\"RmFicvQBAkgADLaPh42HG7CRiaHZ7ZHntXmlQ7rDcMKiaHv82Vm21SBIlMzplBWm1j91vPxm2tabNla08LenJKAow\"\/<\/figure><\/div>\n\n
Illumina\u8fd1\u4e94\u5e74\u8425\u6536\u589e\u957f\u8fd180%\uff0c\u6bdb\u5229\u7387\u9ad8\u8fbe70%\uff0c\u4f46\u662f\u4ece\u8fd1\u4e94\u5b63\u5ea6\u6765\u770b\uff0c\u4e1a\u7ee9\u589e\u901f\u653e\u7f13\uff0c\u4ece2018\u5e74\u6bcf\u5b63\u5ea620%\u7684\u8425\u6536\u589e\u5e45\uff0c\u52302019\u5e74\u524d\u4e24\u4e2a\u5b63\u5ea6\u589e\u5e45\u53ea\u6709\u4e2a\u4f4d\u6570\u3002\u53d7\u9650\u4e8e\u5168\u7403\u8303\u56f4\u5185\u961f\u5217\u7814\u7a76\u9879\u76ee\u91c7\u8d2d\u4eea\u5668\u7684\u9971\u548c\uff0c\u4ee5\u53caDTC\u57fa\u56e0\u68c0\u6d4b\u5e02\u573a\u7684\u75b2\u8f6f\uff0c\u65e9\u5148\u4e2d\u56fd\u5e02\u573a\u8fc7\u591a\u91c7\u8d2d\u56e4\u79ef\u7684\u6d4b\u5e8f\u4eea\u4ecd\u5f85\u5408\u7406\u5229\u7528\u3002<\/div>\n
\u00a0<\/div>\n
Thermo Fisher\u548cIllumina\u4e00\u6837\u4e5f\u5bf9\u4e2d\u56fd\u5e02\u573a\u548c\u4e34\u5e8a\u5e02\u573a\u62b1\u4ee5\u539a\u671b\u3002\u4e0d\u540c\u7684\u662fThermo Fisher\u4e1a\u52a1\u591a\u5143\u5316\uff0c\u4f53\u91cf\u5927\uff0c\u62e5\u6709\u66f4\u591a\u589e\u957f\u70b9\uff0c\u5e76\u901a\u8fc7\u6536\u8d2d\u8fdb\u884c\u5168\u76d8\u5e03\u5c40\u589e\u5f3a\u7efc\u5408\u5b9e\u529b\uff0cNGS\u5c5e\u5176\u751f\u547d\u79d1\u5b66\u89e3\u51b3\u65b9\u6848\u90e8\u95e8\uff0c2018\u5e74\u8be5\u90e8\u95e8\u6536\u5165\u5360\u603b\u6536\u5165\u56db\u5206\u4e4b\u4e00\uff0c\u4e34\u5e8aNGS\u6d4b\u5e8f\u4e5f\u662f\u5176\u4e1a\u52a1\u589e\u957f\u5173\u952e\u9a71\u52a8\u56e0\u7d20\u4e4b\u4e00\u3002<\/div>\n
\u00a0<\/div>\n
\u534e\u5927\u57fa\u56e0\uff08BGI\uff09\u8fd1\u4e94\u5e74\u8425\u6536\u7ffb\u756a\uff0c2018\u5e74\u4e3b\u8981\u4e1a\u52a1\u751f\u80b2\u5065\u5eb7\u7c7b\u670d\u52a1\u4ecd\u5360\u6bd4\u8fc7\u534a\uff0854.4%\uff09\uff0c\u6bdb\u5229\u7387\u6700\u9ad8\uff0869%\uff09\u3002\u79d1\u6280\u670d\u52a1\u6bdb\u5229\u7387\u548c\u589e\u901f\u653e\u7f13\uff0c\u800c\u80bf\u7624\u548c\u611f\u67d3\u4e1a\u52a1\u53d1\u5c55\u8f83\u6162\u4ecd\u6709\u589e\u957f\u7a7a\u95f4\u3002\u8fd1\u4e24\u5b63\u5ea6\u51fa\u73b0\u5229\u6da6\u4e0b\u6ed1\uff0c\u4e0e\u7ba1\u7406\u6210\u672c\u548c\u9500\u552e\u6295\u5165\u589e\u591a\u76f8\u5173\u3002\u8d1d\u745e\u57fa\u56e0\uff08BerryGenomics\uff09\u8fd1\u4e94\u5e74\u4e1a\u52a1\u7ffb\u4e86\u56db\u500d\uff0c\u5728NIPT\u9886\u57df\u74dc\u5206\u4e86\u8fd1\u534a\u6570\u5e02\u573a\uff0cNIPT Plus\u7814\u7a76\u83b7\u5f97\u9636\u6bb5\u6027\u6210\u679c\uff0c\u9664\u4e86\u8bbe\u7f6e\u80bf\u7624\u8d5b\u9053\u5b50\u516c\u53f8\u548c\u745e\u57fa\u56e0\uff0c\u66f4\u5f00\u62d3\u4e86\u6d88\u8d39\u7ea7\u57fa\u56e0\u68c0\u6d4b\u5b50\u516c\u53f8\u5706\u57fa\u56e0\uff0c\u4f46\u540e\u8005\u7814\u53d1\u6295\u5165\uff086%\uff09\u8fd8\u672a\u663e\u793a\u51fa\u8f83\u5f3a\u51b3\u5fc3\u3002<\/div>\n
\u00a0<\/div>\n
\u4e03\u3001\u51c6\u4e0a\u5e02\u4f01\u4e1a\u6d45\u6790<\/div>\n
\u8bfa\u79be\u81f4\u6e90\uff1a\u8bfa\u79be\u81f4\u6e90\u4ece2018\u5e7412\u6708\u6b63\u5f0f\u516c\u5f00\u62ab\u9732IPO\u62db\u80a1\u8bf4\u660e\u4e66\uff0c\u62df\u767b\u9646\u521b\u4e1a\u677f\uff0c\u636e\u5a92\u4f53\u62a5\u9053\uff0c\u8bfa\u79be\u81f4\u6e902016\u5e74\u79d1\u6280\u670d\u52a1\u6536\u5165\u5df2\u8fbe\u52306\u4ebf\uff0c\u548c\u534e\u5927\u57fa\u56e0\u76f8\u5f53\uff0c\u5c5e\u4e8e\u56fd\u5185\u79d1\u6280\u670d\u52a1\u9f99\u5934\uff0c\u521b\u59cb\u56e2\u961f\u4ee5\u6280\u672f\u89c1\u957f\uff0c\u76ee\u524d\u4e1a\u52a1\u5df2\u8986\u76d6\u79d1\u6280\u670d\u52a1\u3001\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u548c\u9057\u4f20\u75c5\u68c0\u6d4b\u4e09\u5927\u9886\u57df\uff0c\u80bf\u7624NGS\u6279\u4ef6\u5728\u624b\uff0c\u540c\u65f6\u62e5\u6709\u653f\u5e9c\u80cc\u666f\u6295\u8d44\u65b9\u7684\u652f\u6301\u3002\u4e5f\u66fe\u8bd5\u6c34\u6d88\u8d39\u7ea7\u57fa\u56e0\u68c0\u6d4b\u9886\u57df\uff0c\u4f46\u672a\u5927\u9762\u79ef\u63a8\u5e7f\uff0c\u603b\u4f53\u800c\u8a00\u6a2a\u5411\u6269\u5f20\u76f8\u5bf9\u4fdd\u5b88\uff0c\u4f46\u90e8\u5206\u9886\u57df\u7684\u6280\u672f\u4f18\u52bf\u660e\u663e\u3002<\/div>\n
\u00a0<\/div>\n
\u534e\u5927\u667a\u9020\uff08MGI\uff09\uff1a\u636e\u62a5\u9053\uff0c\u534e\u5927\u96c6\u56e2\u65d7\u4e0b\u7684\u534e\u5927\u667a\u9020\u5df2\u7d2f\u8ba1\u6295\u5165\u7ea650\u4ebf\u5143\u7814\u53d1\u7ecf\u8d39\uff0c\u5b9e\u73b0\u6d4b\u5e8f\u6280\u672f\u6e90\u5934\u5f0f\u4e13\u5229\u5e03\u5c40\uff0c\u80cc\u9760\u534e\u5927\u96c6\u56e2\u7684\u8d44\u6e90\u4f18\u52bf\u548c\u8d44\u672c\u652f\u6301\uff0c\u6b64\u524d\u6d88\u606f\u4f20\u51fa\u534e\u5927\u667a\u9020\u62df\u8d74\u6e2f\u4e0a\u5e02\uff0c\u9884\u8ba1\u6700\u65e9\u6709\u671b\u57282020\u5e74\u4e0a\u5e02\uff0c\u4e0a\u5e02\u5730\u70b9\u4e0d\u6392\u9664\u79d1\u521b\u677f\u3002\u534e\u5927\u667a\u9020\u62e5\u6709\u4e0a\u6e38\u9886\u57df\u6781\u5177\u4f18\u52bf\u7684\u6280\u672f\u53ca\u5e02\u573a\u5148\u53d1\u4f18\u52bf\uff0c\u4e0d\u5bb9\u5ffd\u89c6\u7684\u6709\u4e24\u65b9\u9762\uff0c\u6280\u672f\u4e0a\u7684\u4f9b\u5e94\u94fe\u4f53\u7cfb\u4ee5\u53ca\u4e09\u4ee3\u6d4b\u5e8f\u7684\u7cbe\u51c6\uff0c\u5e02\u573a\u4e0a\u6709\u90e8\u5206\u662f\u6765\u81ea\u5176\u96c6\u56e2\u4e0b\u5c5e\u5176\u4ed6\u5b50\u516c\u53f8\u7684\u91c7\u8d2d\uff0c\u6709\u5b58\u5728\u95f2\u7f6e\u72b6\u6001\u3002\u968f\u7740\u5728\u751f\u4ea7\u7a33\u5b9a\u3001\u8d28\u63a7\u4e0a\u7684\u6280\u672f\u4f18\u5316\u540e\uff0c\u8fd9\u65b9\u9762\u6709\u671b\u63d0\u5347\u3002\u4e0a\u5e02\u8282\u70b9\u4e5f\u4f1a\u6ce2\u53ca\u5e76\u5217\u7684\u5144\u5f1f\u516c\u53f8\u534e\u5927\u57fa\u56e0\uff08BGI\uff09\u7684\u4f30\u503c\u3002<\/div>\n
\u00a0<\/div>\n
\u71c3\u77f3\u533b\u5b66\uff1a2014\u5e74\u521b\u7acb\uff0c\u76ee\u524d\u878d\u8d44\u9636\u6bb5\u8fdb\u5165C\u8f6e\uff0c\u5df2\u5b8c\u6210\u56db\u8f6e\u878d\u8d44\u603b\u989d\u8d8513\u4ebf\u5143\uff0c\u662f\u6700\u65e9\u4e00\u6279\u8fdb\u5165\u80bf\u7624\u7cbe\u51c6\u533b\u7597\u8d5b\u9053\u7684\u660e\u661f\u4f01\u4e1a\u3002\u4e1a\u52a1\u8986\u76d6\u80bf\u7624\u7528\u836f\u6307\u5bfc\u3001\u4f34\u968f\u8bca\u65ad\u3001\u80bf\u7624\u65e9\u7b5b\u7b49\u5168\u6d41\u7a0b\u573a\u666f\uff0c\u62e5\u6709\u4e2d\u56fd\u7b2c\u4e00\u95f4CLIA\u8ba4\u8bc1\u7684ctDNA\u548c\u80bf\u7624\u7ec4\u7ec7NGS\u5b9e\u9a8c\u5ba4\u3001\u9996\u4e2a\u83b7NMPA\u6279\u51c6\u7684\u80bf\u7624NGS\u68c0\u6d4b\u8bd5\u5242\u76d2\uff0c\u517c\u5177\u6295\u8d44\u548c\u6280\u672f\u5927\u5496\u80cc\u666f\u7684\u521b\u4e1a\u56e2\u961f\u4f7f\u5176\u5bf9\u884c\u4e1a\u8ba4\u77e5\u66f4\u5145\u5206\u66f4\u654f\u9510\uff0c\u5728\u7814\u53d1\u548c\u6e20\u9053\u4e0a\u5747\u62e5\u6709\u624e\u5b9e\u529f\u5e95\u3002<\/div>\n
\u00a0<\/div>\n
\u4e16\u548c\u57fa\u56e0\uff1a2013\u5e74\u6210\u7acb\uff0c\u968f\u540e\u4e0e\u5357\u4eac\u653f\u5e9c\u5171\u5efa\u5357\u4eac\u9ad8\u65b0\u7cbe\u51c6\u533b\u5b66\u4e2d\u5fc3\uff0c\u83b7\u5f97\u4e0a\u5e02\u516c\u53f8\u5317\u9646\u836f\u4e1a\u7684\u8d44\u91d1\u652f\u6301\u548c\u8d44\u6e90\u5e73\u53f0\u3002\u636e\u62a5\u9053\uff0c\u4e16\u548c\u57fa\u56e02017\u5e74\u5b9e\u73b0\u6536\u51651.8\u4ebf\u5143\uff0c2018\u5e74\u9884\u8ba1\u8fd13\u4ebf\u6536\u5165\uff0c\u5df2\u57fa\u672c\u5b9e\u73b0\u76c8\u5229\uff0c\u5e76\u4e14\u4e0e\u5168\u56fd450\u591a\u5bb6\u4e09\u7532\u533b\u9662\u548c\u80bf\u7624\u4e13\u79d1\u533b\u9662\u5efa\u7acb\u6709\u5408\u4f5c\uff0c\u968f\u77402018\u5e74\u4e0b\u534a\u5e74\u62ff\u4e0b\u80bf\u7624NGS\u6279\u4ef6\u3001\u8425\u9500\u63a8\u5e7f\u5feb\u901f\u94fa\u5f00\u4ee5\u53ca\u5357\u4eac\u6c5f\u5317\u65b0\u533a\u7684\u91cd\u70b9\u6276\u6301\uff0c\u4e16\u548c\u57fa\u56e0\u7684\u5730\u7406\u5dee\u5f02\u5316\u4f18\u52bf\u660e\u663e\u3002<\/div>\n
\u00a0<\/div>\n
\u516b\u3001\u672a\u6765\u53d1\u5c55\u8d8b\u52bf\u7684\u601d\u8003<\/div>\n
1. \u80bf\u7624\u57fa\u56e0\u7b49\u9886\u57df\u7684\u6d17\u724c<\/div>\n
\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u884c\u4e1a\u63a5\u8fde\u4e24\u5e74\u4f5c\u4e3a\u8d44\u672c\u5173\u6ce8\u6700\u70ed\u8d5b\u9053\uff0c\u73b0\u9636\u6bb5\u9996\u6279\u62ff\u8bc1\u7684\u7b2c\u4e00\u68af\u961f\u4f01\u4e1a\u5df2\u62a2\u5148\u5165\u9a7b\u5e02\u573a\uff0c\u9664\u4e86\u90e8\u5206\u5c0f\u800c\u7f8e\u624e\u6839\u7ec6\u5206\u9886\u57df\u7684\u80bf\u7624\u4f01\u4e1a\uff0c\u672a\u6765\u4e00\u4e24\u5e74\u5185\u5927\u591a\u6570\u540c\u8d28\u5316\u80bf\u7624\u4f01\u4e1a\u6216\u5c06\u9762\u4e34\u6d17\u724c\u6216\u6574\u5408\uff0c\u91d1\u51c6\u57fa\u56e0CEO\u5f20\u6d69\u4ecb\u7ecd\u9053\uff0c\u5f53\u7ec6\u5206\u9886\u57df\u5e02\u573a\u4e3b\u8981\u88ab5\u4e2a\u4ee5\u5185\u516c\u53f8\u5360\u9886\u7684\u65f6\u5019\uff0c\u610f\u5473\u7740\u4e0b\u884c\u6ce2\u6d6a\u5dee\u4e0d\u591a\u8fce\u6765\u7ec8\u7ed3\u3002\u9664\u4e86\u540c\u8d28\u5316\u73b0\u8c61\uff0c\u9605\u5c14\u57fa\u56e0CEO\u67f4\u6620\u723d\u63d0\u5230\uff0c\u5f88\u591a\u80bf\u7624\u516c\u53f8\u7684\u9500\u552e\u65b9\u5f0f\u4e0d\u7b26\u5408\u4e34\u5e8a\u4e3b\u6d41\uff0c\u5982\u9662\u5916\u60a3\u8005\u626b\u7801\u4ed8\u8d39\uff0c\u7c7b\u4f3c\u8fd9\u79cd\u6a21\u5f0f\u5b58\u5728\u5f88\u591a\u5408\u89c4\u6027\u98ce\u9669\uff0c\u7070\u8272\u5730\u5e26\u4e0d\u662f\u4e00\u4e2a\u53ef\u4ee5\u4f9d\u8d56\u7684\u8d22\u52a1\u6a21\u5f0f\u3002\u57fa\u51c6\u533b\u7597\u521b\u59cb\u4eba\u8303\u5efa\u5175\u8ba4\u4e3a\uff0c\u8981\u7a81\u7834\u5f53\u524d\u7684\u8ff7\u5c40\uff0c\u4ea7\u54c1\u5fc5\u987b\u5177\u5907\u4e09\u70b9\uff1a\u4e34\u5e8a\u4ef7\u503c\u3001\u793e\u4f1a\u7ecf\u6d4e\u6548\u76ca\u53ca\u4e34\u5e8a\u53ef\u843d\u5730\u3002<\/div>\n
\u4f01\u4e1a\u5728\u4ea7\u54c1\u7814\u53d1\u4ecd\u9700\u4e0e\u4e34\u5e8a\u771f\u5b9e\u9700\u6c42\u7d27\u5bc6\u7ed3\u5408\uff0c\u6280\u672f\u4e3b\u5bfc\u63a8\u52a8\u4ea7\u54c1\u8fed\u4ee3\uff0c\u4ea7\u54c1\u5408\u89c4\u5c06\u8d8a\u6765\u8d8a\u91cd\u8981\uff0c\u662fNGS\u4f01\u4e1a\u5b58\u6d3b\u7684\u5fc5\u8981\u6761\u4ef6\u3002\u4f01\u4e1a\u9700\u8981\u6709\u6301\u7eed\u589e\u957f\u80fd\u529b\uff0c\u6253\u901a\u6e20\u9053\u81ea\u6211\u9020\u8840\uff0c\u76c8\u5229\u80fd\u529b\u662f\u91cd\u8981\u6307\u6807\u3002<\/div>\n

2. \u65b0\u7684\u5e94\u7528\u65b9\u54111\uff09\u65b0\u751f\u513f\u91cd\u75c7\u76d1\u62a4\u7684\u5feb\u901f\u5168\u57fa\u56e0\u7ec4\u68c0\u6d4b\u7684\u5e94\u7528\uff0c\u5c06\u63a8\u52a8\u65b0\u751f\u513f\u5168\u57fa\u56e0\u7ec4\u7684\u666e\u53ca\u5316\u3002\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u513f\u79d1\u533b\u9662\u526f\u9662\u957f\u5468\u6587\u6d69\u6559\u6388\u63a5\u53d7\u57fa\u56e0\u6167\u91c7\u8bbf\u8ba4\u4e3a\uff0c\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u3001\u5355\u5206\u5b50\u6d4b\u5e8f\u5c06\u9010\u6e10\u5360\u636e\u672a\u6765\u4e34\u5e8a\u68c0\u6d4b\u5e02\u573a\u30022\uff09\u6d88\u8d39\u7ea7\u57fa\u56e0\u68c0\u6d4b\u5c06\u9010\u6e10\u548c\u4e34\u5e8a\u7ea7\u57fa\u56e0\u68c0\u6d4b\u7ed3\u5408\u3002\u7ee7\u53bb\u5e74\u83b7\u5f97BRCA1\/BRCA2\u57fa\u56e0\u7a81\u53d8\u7684\u4e73\u817a\u764c\u98ce\u9669\u68c0\u6d4b\u540e\uff0c23andme\u4eca\u5e741\u6708\u83b7\u5f97FDA\u6279\u51c6\u7684\u7b2c\u4e8c\u6b3e\u764c\u75c7\u98ce\u9669\u76f8\u5173\u68c0\u6d4b\uff0c\u53ef\u4e3a\u6d88\u8d39\u8005\u63d0\u4f9b\u9057\u4f20\u6027\u7ed3\u76f4\u80a0\u764c\u7efc\u5408\u5f81\u98ce\u9669\u68c0\u6d4b\u3002WeGene\u5efa\u7acb\u4e34\u5e8a\u57fa\u56e0\u6269\u589e\u68c0\u9a8c\u5b9e\u9a8c\u5ba4\u3002<\/p>\n

3\uff09\u65e9\u4ea7\u57fa\u56e0\u68c0\u6d4b\u3002\u6bcf\u5e74\u65e9\u4ea7\u513f\u53d1\u751f\u7387\u9ad8\u8fbe\u5341\u5206\u4e4b\u4e00\uff0c\u7ea6\u67091500\u591a\u4e07\uff0c\u65af\u5766\u798f\u5927\u5b66\u7684Stephen Quake\u6559\u6388\u901a\u8fc7\u76ee\u524d\u5916\u5468\u8840\u6e38\u79bb\u7684DNA\u548cRNA\u6d4b\u5e8f\uff0c\u7b5b\u9009\u4e0e\u65e9\u4ea7\u76f8\u5173\u7684\u57fa\u56e0\uff0c\u5e76\u6210\u7acbAkna Dx\u516c\u53f8\uff0c\u9884\u8ba1\u4e94\u5e74\u5185\u8fdb\u5165\u4e34\u5e8a\uff0c\u8fd9\u9879\u7814\u7a76\u88abMIT\u79d1\u6280\u8bc4\u8bba\u5217\u51652019\u5341\u5927\u7a81\u7834\u6027\u6280\u672f\u4e4b\u4e00\u3002<\/div>\n
4\uff09\u80bf\u7624\u53ca\u66f4\u591a\u75be\u75c5\u7684\u4e34\u5e8a\u5fae\u751f\u7269\u7ec4\u68c0\u6d4b\u3002\u968f\u7740iHMP\u53ca\u66f4\u591a\u79d1\u7814\u6210\u679c\uff0c\u663e\u793a\u5fae\u751f\u7269\u7ec4\u53ef\u4f5c\u4e3a\u91cd\u8981\u751f\u7269\u6807\u8bb0\uff0c\u6838\u5fc3\u662f\u4ece\u5b9a\u6027\u5230\u5b9a\u91cf\u3002<\/div>\n
5\uff09\u4e34\u5e8a\u8868\u89c2\u9057\u4f20\u68c0\u6d4b\u00a0\u52a0\u62ff\u5927Greenwood\u9057\u4f20\u4e2d\u5fc3\u63a8\u51fa\u57fa\u4e8eIllumina\u5e73\u53f0\u8868\u89c2\u9057\u4f20\u5b66\u8bca\u65ad\u4ea7\u54c1 EpiSign\uff0c\u5df2\u4e8e4\u6708\u5f00\u59cb\u6b63\u5f0f\u63a5\u53d7\u60a3\u8005\u9884\u5b9a\u548c\u6837\u672c\u9001\u68c0\uff0c\u5176\u4e2d19\u79cd\u5bb6\u65cf\u9057\u4f20\u6027\u75be\u75c5\u7efc\u5408\u5206\u6790\u7684\u8d39\u7528\u4e3a$1500\uff0c4\u5468\u62ff\u5230\u62a5\u544a\u3002<\/div>\n
\u00a0<\/div>\n
3. \u65b0\u6a21\u5f0f<\/div>\n
1\uff09\u533a\u57df\u5316<\/div>\n
1\u6708\uff0c\u8fea\u5b89\u8bca\u65ad\u8054\u54088\u5bb6\u6d59\u6c5f\u7701\u5185\u4e09\u7ea7\u7532\u7b49\u533b\u9662\u5171\u540c\u53d1\u8d77\u56fd\u5185\u9996\u5bb6\u9ad8\u7aef\u68c0\u9a8c\u533b\u5171\u4f53\u8054\u76df\uff1b5\u6708\uff0c\u6df1\u5733\u5e02\u9996\u5bb6\u533a\u57df\u68c0\u9a8c\u4e2d\u5fc3\u2014\u2014\u7f57\u6e56\u533b\u9662\u96c6\u56e2\u533b\u5b66\u68c0\u9a8c\u5b9e\u9a8c\u5ba4\u6b63\u5f0f\u5f00\u4e1a\u3002\u533a\u57df\u5316\u53d1\u5c55\u4e2d\u5fc3\u4e5f\u662f\u534e\u5927\u7b49\u4f01\u4e1a\u7684\u9500\u552e\u7b56\u7565\u4e4b\u4e00\u3002<\/div>\n
2\uff09LDT\u548c\u9662\u5185\u68c0\u6d4b\u7684\u5e76\u5b58<\/div>\n
\u5e7f\u897f\u533b\u79d1\u5927\u5b66\u515a\u59d4\u526f\u4e66\u8bb0\u83ab\u66fe\u5357\u4ecb\u7ecd\u9053\uff0c\u7531\u4e8e\u53d7\u5230\u6536\u8d39\u4ef7\u683c\u3001\u51c6\u5165\u3001\u533b\u751f\u548c\u60a3\u8005\u63a5\u53d7\u7a0b\u5ea6\u7b49\u56e0\u7d20\u7684\u5f71\u54cd\uff0c\u533b\u9662\u81ea\u5efa\u5b9e\u9a8c\u5ba4\u96be\u4ee5\u5927\u89c4\u6a21\u666e\u53ca\u3002\u672a\u6765\u533b\u9662LDT\u548c\u9662\u5185\u68c0\u6d4b\u5c06\u6210\u4e3a\u672a\u6765\u57fa\u56e0\u68c0\u6d4b\u4e24\u79cd\u5e76\u5b58\u65b9\u5f0f\uff0c\u4e13\u4e1a\u4eba\u624d\u7684\u77ed\u7f3a\u4ecd\u662f\u75db\u70b9\uff0c\u9700\u8981\u56fd\u5bb6\u91cd\u89c6\u548c\u9ad8\u6821\u7684\u4e13\u4e1a\u6559\u80b2\/\u804c\u4e1a\u6559\u80b2\u7684\u91cd\u89c6\u3002<\/div>\n
3\uff09\u56fd\u9645\u4f01\u4e1a\u7684\u751f\u4ea7\u57fa\u5730\u5f15\u8fdb\u548c\u7ade\u4e89\u5e73\u8861<\/div>\n
\u968f\u77402016\u5e74\uff0c\u897f\u95e8\u5b50\u533b\u7597\u5ba3\u5e03\u4e9a\u592a\u533a\u9996\u4e2a\u8bca\u65ad\u8bd5\u5242\u5de5\u5382\u843d\u6237\u4e0a\u6d77\uff0c2018\u5e74\uff0c\u7f57\u6c0f\u8bca\u65ad\u4e9a\u592a\u751f\u4ea7\u57fa\u5730\u5728\u82cf\u5dde\u5de5\u4e1a\u56ed\u533a\u6b63\u5f0f\u843d\u6210\u30022019\u5e744\u6708\uff0c\u6cd5\u56fd\u751f\u7269\u6885\u91cc\u57c3\u5ba3\u5e03\u5c06\u5728\u82cf\u5dde\u9ad8\u65b0\u533a\u6295\u8d44\u5efa\u8bbe\u4f53\u5916\u8bca\u65ad\u4ea7\u54c1\u751f\u4ea7\u57fa\u5730\u3002\u4ee5\u4e0a\u56fd\u9645\u4f01\u4e1a\u751f\u4ea7\u57fa\u5730\u96c6\u4e2d\u5728\u82cf\u5dde\u548c\u4e0a\u6d77\uff0c\u672a\u6765\u5728\u6df1\u5733\u7b49\u5730\u53ef\u4ee5\u9884\u89c1\u6d77\u5916\u6d4b\u5e8f\u5de5\u5382\u6216\u8bd5\u5242\u751f\u4ea7\u57fa\u5730\u5c06\u843d\u6237\uff0c\u4e0e\u56fd\u5185\u5934\u90e8\u4f01\u4e1a\u5f62\u6210\u7ade\u4e89\u5e73\u8861\u3002<\/div>\n
4\uff09\u6570\u5b57PCR\u7684\u79ef\u7d2f<\/div>\n
\u76f8\u5bf9\u4e8e\u76f8\u5bf9\u4e8eNGS\uff0c dPCR\u5bf9\u5df2\u77e5\u57fa\u56e0\u68c0\u6d4b\u6709\u76f8\u5bf9\u4f18\u52bf\uff0c\u5305\u62ec\u5bcc\u96c6\u5f85\u6d4b\u5e8f\u6837\u54c1\u4e2d\u7684\u9776\u57fa\u56e0\uff0c\u9a8c\u8bc1\u6d4b\u5e8f\u7ed3\u679c\u548c\u57fa\u56e0\u7f16\u8f91\u7ed3\u679c\u3002\u6839\u636e\u4eea\u5668\u4fe1\u606f\u7f51\u63a8\u51fa\u7684\u300a2019\u5e74PCR\u4eea\u4e0a\u534a\u5e74\u4e2d\u6807\u76d8\u70b9\u300b\uff0c\u5728405\u6761PCR\u6709\u6548\u4e2d\u6807\u4fe1\u606f\u4e2d\uff0c\u9ad8\u6821\u548c\u533b\u9662\u5360\u91c7\u8d2d\u768465%\uff0c\u8d5b\u9ed8\u98de\u3001\u4f2f\u4e50\u3001\u7f57\u6c0f\u3001\u8d5b\u6c9b4\u5927\u8fdb\u53e3\u54c1\u724c\u5305\u63fd80%\u8ba2\u5355\u3002<\/div>\n
\u00a0<\/div>\n
2011\u5e74\u8d77\uff0c\u5404\u5bb6\u516c\u53f8\u901a\u8fc7\u6536\u8d2d\u548c\u6295\u8d44\u6765\u8fdb\u519b\u6570\u5b57PCR\u5e02\u573a\uff0c\u5305\u62ec\u4f2f\u4e50\u516c\u53f8\u6536\u8d2dQuantaLife\u548cRainDance\uff0c\u8d5b\u9ed8\u98de\u4e16\u5c14\u6536\u8d2dLife Technologies\uff0cIllumina \u9886\u6295Stilla Technologies\uff0c\u51ef\u6770\u6536\u8d2dFormulatrix\u7b49\u3002Roche\u4e5f\u5728\u4eca\u5e74\u5ba3\u5e03\u6570\u5b57PCR\u4eea\u6b63\u5904\u4e8e\u539f\u578b\u7814\u53d1\u9636\u6bb5\uff0c<\/div>\n
\u56fd\u5185\u6570\u5b57PCR\u5382\u5546\u5305\u62ec\u9886\u822a\u751f\u7269(\u8fd1\u5e74\u83b7\u6d59\u6c5f\u7701\u836f\u76d1\u5c40\u6279\u51c6\u4e0a\u5e02)\u3001\u65b0\u7fbf\u751f\u7269\uff08\u548c\u5317\u4eac\u5927\u5b66\u90ed\u6c38\u6559\u6388\u5408\u4f5c\u7814\u53d1\uff09\u3001\u5361\u5c24\u8fea\uff08\u4e13\u6ce8\u6bcd\u5a74\uff09\u3001\u8bfa\u79be\u81f4\u6e90\uff08\u8d5b\u9ed8\u98deOEM\uff09\u7b49\u3002<\/div>\n
5\uff09\u8d28\u8c31\u53caNGS\u7684\u7ed3\u5408<\/div>\n
\u534e\u5927\u8054\u5408\u521b\u59cb\u4eba\u5218\u65af\u5947\u56de\u5f52\u540e\u62c5\u5f53\u534e\u5927\u8d28\u8c31\u8d1f\u8d23\u4eba\uff0c\u57285\u6708\uff0c\u534e\u5927\u7f8e\u56fd\u8d28\u8c31\u4e2d\u5fc3\u6b63\u5f0f\u6210\u7acb\u5e76\u4e8eThermo Fisher\u5408\u4f5c\u53d1\u5e03\u65b0\u4ea7\u54c1\uff0c\u63d0\u4f9b\u86cb\u767d\u8d28\u7ec4\u5b66\u548c\u836f\u7269\u8868\u5f81\u7b49\u4e00\u7cfb\u5217\u8d28\u8c31\u670d\u52a1\u4ee5\u53ca\u4e0e\u6d4b\u5e8f\u6570\u636e\u7684\u8054\u5408\u5206\u6790\u670d\u52a1\u3002\u540c\u6708\uff0c\u201c\u4e34\u5e8a\u8d28\u8c31\u7814\u7a76\u4e0e\u4ea7\u4e1a\u8054\u76df\u201d\u5728\u6df1\u5733\u6b63\u5f0f\u6210\u7acb\uff0c\u7531\u5f20\u7389\u594e\u9662\u58eb\u62c5\u4efb\u987e\u95ee\u56e2\u4e3b\u5e2d\uff0c\u5e9c\u4f1f\u7075\u6559\u6388\u4efb\u7406\u4e8b\u957f\u3002\u65e5\u524d\uff0c\u8fea\u5b89\u8bca\u65ad\u65d7\u4e0b\u7684\u8fea\u8c31\u8bca\u65ad\u4e0e\u5168\u7403\u552f\u4e00\u83b7\u5f97FDA\u8ba4\u53ef\u7684\u6838\u9178\u8d28\u8c31\u6280\u672f\u5f00\u53d1\u751f\u4ea7\u5382\u5546Agena\u5408\u4f5c\u5efa\u7acb\u6838\u9178\u8d28\u8c31\u5e94\u7528\u793a\u8303\u4e2d\u5fc3\uff0c\u53ef\u4ee5\u9884\u89c1\u672a\u6765NGS\u4e0e\u8d28\u8c31\u7684\u7efc\u5408\u670d\u52a1\u5c06\u9646\u7eed\u5f97\u5230\u6548\u4eff\u3002<\/div>\n
\u66f4\u591a\u89c2\u70b9\u8bf7\u5173\u6ce8\u5fae\u4fe1\u516c\u4f17\u53f7\u201c\u57fa\u56e0\u6167\u201d\u5373\u5c06\u53d1\u5e03\u7684\u4e0b\u96c6\u3002<\/div>\n
\u00a0<\/div>\n
\u3010\u7ed3\u8bed\u3011<\/div>\n
\u57fa\u56e0\u68c0\u6d4b\u4ecd\u6709\u6a2a\u5411\u548c\u7eb5\u5411\u62d3\u5c55\u7684\u84dd\u6d77\u673a\u9047\u548c\u884c\u4e1a\u4f7f\u547d\uff0c\u9664\u6b64\u4e4b\u5916\uff0c\u57fa\u56e0\u7f16\u8f91\u548c\u57fa\u56e0\u6cbb\u7597\uff0c\u57fa\u56e0\u5408\u6210\u53caDNA\u5b58\u50a8\u7b49\u65b0\u6280\u672f\u5c06\u6253\u7834\u8fb9\u754c\uff0c\u5c06\u57fa\u56e0\u4e0e\u65b0\u836f\u3001IT\u3001AI\u53ca\u533a\u5757\u94fe\u7b49\u878d\u5408\uff0c\u5c06\u6210\u4e3a\u65b0\u7684\u4ea7\u4e1a\u6d6a\u6f6e\u3002\u8fd9\u91cc\u9700\u8981\u66f4\u591a\u7684\u653f\u7b56\u5f15\u5bfc\u3001\u8d44\u91d1\u652f\u6301\u3001\u5934\u90e8\u4f01\u4e1a\u7684\u5f00\u653e\u7684\u683c\u5c40\u548c\u7ec6\u5206\u9886\u57df\u521b\u4e1a\u8005\u7684\u957f\u8fdc\u6218\u7565\u773c\u5149\u3002<\/div>\n
\u57fa\u56e0\u4ea7\u4e1a\u7684\u9ece\u660e\u9759\u6084\u6084\uff0c\u805a\u96c6\u4e8e\u5cb8\u8fb9\u7684\uff0c\u5982\u540c15\u5e74\u524d\u5bf9\u4e92\u8054\u7f51\u7684\u89c2\u671b\uff0c\u805a\u96c6\u4e8e\u6ce1\u6cab\u7684\u5728\u53f9\u606f\uff0c\u805a\u96c6\u4e8e\u521b\u65b0\u7684\u5728\u5450\u558a\uff0c\u800c\u8df3\u51fa\u6765\u5efa\u8bbe\u6865\u6881\u53ca\u751f\u6001\u5708\u7684\u5728\u9759\u6084\u6084\u6492\u7f51\uff0c\u4f46\u6240\u6709\u4eba\u90fd\u5728\u6478\u7740\u6c99\u6ee9\u9020\u8239\u8fc7\u6d77\uff0c\u6e85\u8d77\u7684\u6bcf\u4e00\u7247\u6d6a\u82b1\u90fd\u6709\u7740\u6f6e\u6d41\u7684\u529b\u91cf\uff0c\u5341\u5e74\u540e\u65b0\u4e00\u5ea7\u4ea7\u4e1a\u9ad8\u5cf0\u4e0a\uff0c\u53ef\u4ee5\u56de\u89c1\u66fe\u7ecf\u7684\u4f60\u4e8e\u6b64\u65f6\u6478\u7d22\u7684\u52c7\u6c14\u548c\u575a\u6301\u7684\u76ee\u5149\u3002<\/div>\n
\u00a0<\/div>\n
\u52a0\u5165\u57fa\u56e0\u6167\u8bfb\u8005\u7fa4\u6216\u5546\u52a1\u5408\u4f5c<\/div>\n
\u8bf7\u6dfb\u52a0\u5fae\u4fe1\uff1ajiyinhui_1<\/div>\n
\u901a\u5173\u53e3\u4ee4\uff1a\u5907\u6ce8\u5355\u4f4d-\u804c\u4f4d-\u59d3\u540d<\/div>\n\n
\n
\"RmFicvQBAkgBoibxibQnRGrszjh1WnbBb98VaAJf2h5PCf1bm5YyUqqjc5jkb0KicS11ECIjUPDM1rbFx8Lt0tP1kQ\"\/<\/figure><\/div>\n\n
\u62d3\u5c55\u9605\u8bfb\u00a0<\/div>\n
1998-2018\uff0c\u7ec6\u6570\u57fa\u56e0\u4ea7\u4e1a20\u5e74<\/a><\/div>\n
2018\u5e74\uff08\u4e0a\uff09\uff1a\u751f\u547d\u5065\u5eb7\u4f01\u4e1a\u7684\u6536\u8d2d\u903b\u8f91<\/a>\u00a0<\/div>\n
\u57fa\u56e0\u884c\u4e1a2018\u5e74\u5ea6\u76d8\u70b9\uff08\u4e00\uff09<\/a><\/div>\n
\u300a2019\u5e74\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b<\/a><\/div>\n
\u00a0<\/div>\n
\u00a0\u57fa\u56e0\u6167\u62db\u8058\u00a0<\/div>\n
\u57fa\u56e0\u884c\u4e1a\u6b63\u5728\u7ecf\u538615\u5e74\u524d\u7684\u4e92\u8054\u7f51\u5468\u671f<\/div>\n
\u8d44\u6e90\u914d\u7f6e\u4ece\u6492\u8c46\u6210\u5175\u5230\u767e\u5ddd\u5165\u6d77<\/div>\n
\u4fe1\u606f\u6218\u7565\u662f\u6b64\u65f6\u7684\u9996\u8981\u5143\u7d20<\/div>\n
\u57fa\u56e0\u6167\u9080\u8bf7\u60a8\u6210\u4e3a\u884c\u4e1a\u4fe1\u606f\u4e13\u5bb6\uff0c\u5148\u4e00\u6b65\u770b\u89c1\u672a\u6765<\/div>\n
\u5982\u679c\u60a8\u5728\u65b0\u5a92\u4f53\u3001\u57fa\u56e0\u5e02\u573a\u7b49\u67091+\u5e74\u7ecf\u9a8c\uff0c\u70ed\u7231\u57fa\u56e0\u884c\u4e1a\uff0c\u6b22\u8fce\u52a0\u5165\u6211\u4eec\u3002\u7b80\u5386\u6295\u9012\u90ae\u7bb1\uff1ainfo@genonet.cn<\/div>\n
\u00a0<\/div>\n
\u3010\u5173\u4e8e\u57fa\u56e0\u6167\u3011<\/div>\n
\u57fa\u56e0\u6167\u662f\u4e00\u5bb6\u7b2c\u4e09\u65b9\u57fa\u56e0\u548c\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u521b\u65b0\u670d\u52a1\u673a\u6784\uff0c\u6210\u7acb\u4e8e2016\u5e74\uff0c\u57fa\u4e8e10\u5e74\u4ea7\u4e1a\u5b9e\u8df5\u7684\u56e2\u961f\uff0c\u6211\u4eec\u5efa\u7acb\u4e86\u4e13\u5bb6\u667a\u5e93\u3001\u6570\u636e\u5e93YourMap\u548c\u4e13\u4e1a\u5a92\u4f53\u54c1\u724c\uff0c\u63d0\u4f9b\u4ea7\u4e1a\u54a8\u8be2\u57f9\u8bad\u3001\u79d1\u6280\u5a92\u4f53\u548c\u4fe1\u606f\u670d\u52a1\uff0c\u81f4\u529b\u4e8e\u5efa\u7acb\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u4fe1\u606f\u5927\u6570\u636e\u5e73\u53f0\uff0c\u5e2e\u52a9\u5408\u4f5c\u4f19\u4f34\u65e9\u4e00\u6b65\u770b\u89c1\u672a\u6765\u3002<\/div>\n
\u00a0<\/div>\n
\u3010\u90e8\u5206\u8363\u8a89\u3011<\/div>\n
\u56fd\u5bb6\u53d1\u6539\u59d4\u300a2019\u5e74\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b\u7f16\u59d4\u7684\u5355\u4f4d<\/div>\n
\u5168\u56fd\u536b\u751f\u4ea7\u4e1a\u4f01\u4e1a\u7ba1\u7406\u534f\u4f1a\u7cbe\u51c6\u533b\u7597\u5206\u4f1a\u7406\u4e8b\u7684\u5355\u4f4d<\/div>\n
\u54c8\u5c14\u6ee8\u5de5\u4e1a\u5927\u5b66\uff08\u6df1\u5733\uff09\u300a\u751f\u7269\u4ea7\u4e1a\u5206\u6790\u300b\u8bfe\u7a0b\u5408\u4f5c\u5355\u4f4d<\/div>\n
\u300a\u4e34\u5e8a\u751f\u7269\u6837\u672c\u5e93\u63a2\u7d22\u4e0e\u5b9e\u8df5<\/a>\u300b\u7684\u7f16\u59d4\u5355\u4f4d<\/div>\n
\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5b66\u4f1a\u653f\u7b56\u7814\u7a76\u5206\u4f1a\u5e38\u59d4\u7684\u5355\u4f4d<\/div>\n
\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5b66\u4f1a\u9057\u4f20\u75c5\u5206\u4f1a\u5e38\u59d4\u7684\u5355\u4f4d<\/div>\n
\u6df1\u5733\u5e02\u5065\u5eb7\u4ea7\u4e1a\u53d1\u5c55\u4fc3\u8fdb\u4f1a\u526f\u4f1a\u957f\u5355\u4f4d<\/div>\n
\u53d1\u5e03\u4e86\u300a2019 \u5e74\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b<\/a>\u7b49\u884c\u4e1a\u6743\u5a01\u62a5\u544a<\/div>\n
\u53c2\u4e0e\u7ec4\u7ec7\u53d1\u5e03\u300a\u4e34\u5e8a\u57fa\u56e0\u68c0\u6d4b\u62a5\u544a\u89c4\u8303\u4e0e\u57fa\u56e0\u68c0\u6d4b\u884c\u4e1a\u5171\u8bc6\u300b<\/a>\u53ca\u76f8\u5173\u56e2\u4f53\u6807\u51c6<\/div>\n
\u4e3b\u529e\u9996\u5c4a\u6570\u5b57\u5065\u5eb7\u79c1\u8463\u4f1a<\/a><\/div>\n
\u4e3b\u529e\u9996\u5c4a\u7ca4\u6e2f\u6fb3\u5927\u6e7e\u533a\u751f\u547d\u5065\u5eb7\u521b\u65b0\u8bba\u575b<\/a><\/div>\n
\u534f\u529e\u7b2c\u4e00\u5c4a<\/a>\u548c\u7b2c\u4e8c\u5c4a\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\u5927\u4f1a<\/a><\/div>\n
\u00a0<\/div>\n
\u6b22\u8fce\u4ea7\u4e1a\u56ed\u533a\u3001\u91d1\u878d\u673a\u6784\u3001\u5b66\u4f1a\u53ca\u8054\u76df\u3001\u653f\u5e9c\u53ca\u4f01\u4e1a\u7b49\u5408\u4f5c\uff0c\u5728\u57fa\u56e0\u4ea7\u4e1a\u7684\u7b2c\u4e00\u9636\u6bb5\u7206\u53d1\u540e\u7684\u878d\u5408\u671f\uff0c\u57fa\u4e8e\u4ea7\u4e1a\u56fe\u8c31\uff0c\u65e9\u4e00\u6b65\u770b\u89c1\u672a\u6765\u3002\uff08\u8054\u7cfb\u65b9\u5f0f\uff1a400-088-7466\uff0cinfo@genonet.cn\uff09<\/div>\n
\u3010\u58f0\u660e\u3011\u4ee5\u4e0a\u6587\u7ae0\u4e3a\u884c\u4e1a\u76f8\u5173\u8d44\u8baf\u548c\u5206\u6790\u6587\u7ae0\uff0c\u4ec5\u4ee3\u8868\u4f5c\u8005\u4e2a\u4eba\u89c2\u70b9\uff0c\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u4e0d\u4f5c\u4e3a\u6295\u878d\u8d44\u53ca\u533b\u7597\u7b49\u51b3\u7b56\u4f9d\u636e\uff1b\u6587\u7ae0\u7684\u77e5\u8bc6\u7248\u6743\u5c5e\u4e8e\u57fa\u56e0\u6167\uff0c\u673a\u6784\u8f6c\u8f7d\u8bf7\u5728\u6587\u7ae0\u4f5c\u8005\u4ee5\u53ca\u6b63\u6587\u9996\u884c\u6ce8\u660e\u201c\u8f6c\u8f7d\u81ea\u57fa\u56e0\u6167\u201d\uff0c\u8fdd\u8005\u5c06\u4fdd\u7559\u6cd5\u5f8b\u8ffd\u7a76\u6743\u5229\uff1b\u6b22\u8fce\u4e2a\u4eba\u8f6c\u53d1\u5206\u4eab\u3002<\/div>\n\n
\n
\"RmFicvQBAkgDwDDlibn6LGMERd60A1XgibkVTEVrPEb1EoTK1HnjticKMtrzWS4eyuZgibs4H2ErBL6cp0GRTKvEAkg\"\/<\/figure><\/div>","protected":false},"excerpt":{"rendered":"

\u57fa\u56e0\u4ea7\u4e1a2019\u5e74\u534a\u7a0b\u76d8\u70b9\uff08\u4e0a\uff09<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[1612],"class_list":["post-9235","post","type-post","status-publish","format-standard","hentry","category-industryresearch","tag-1612"],"_links":{"self":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9235","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/comments?post=9235"}],"version-history":[{"count":4,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9235\/revisions"}],"predecessor-version":[{"id":13945,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9235\/revisions\/13945"}],"wp:attachment":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/media?parent=9235"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/categories?post=9235"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/tags?post=9235"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}