{"id":9138,"date":"2020-03-16T09:29:55","date_gmt":"2020-03-16T01:29:55","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100012855&idx=1&sn=ef984fc34d5d2744d7882f3ef6e2f53a&chksm=6b7141805c06c8961a98af6bbcd69f9b5cf5b286eb053b4353b4f31e12241ba1940458dad0c1#rd"},"modified":"2026-04-02T10:17:54","modified_gmt":"2026-04-02T02:17:54","slug":"485297","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2020\/03\/16\/485297\/","title":{"rendered":"\u57fa\u56e0\u7b80\u62a5 | \u8bfa\u79beIPO\u7ec8\u6b62\u7b80\u6790\uff0c\u590d\u661f\u8d85$1.3\u4ebf\u5165\u5c40\u65b0\u51a0\u75ab\u82d7\uff0c19\u6b3e\u65b0\u51a0\u68c0\u6d4b\u8bd5\u5242\u76d2"},"content":{"rendered":"
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1. \u5386\u7ecf\u56db\u5e74\u4ece2016\u5e74\u62db\u5546\u8bc1\u5238\u4fdd\u8350\uff0c\u52302018\u5e74\u4e2d\u4fe1\u8bc1\u5238\u4fdd\u8350\uff0c2020\u5e742\u670828\u65e5\uff0c\u8bfa\u79be\u81f4\u6e90\u521b\u4e1a\u677fIPO\u7533\u8bf7\u88ab\u7ec8\u6b62\u5ba1\u67e5\uff0c\u7b80\u6790\u5982\u4e0b\u3002<\/div>\n
2. \u590d\u661f\u533b\u836f\u8d85\u5ba3\u5e03\u8054\u624bmRNA\u7597\u6cd5\u4f01\u4e1aBioNTech\u542f\u52a8\u65b0\u51a0\u75ab\u82d7\u6218\u7565\u5408\u4f5c\uff0c1.3\u4ebf\u7f8e\u5143\u5165\u5c40\u65b0\u51a0\u75ab\u82d7\u6280\u672f\u8bb8\u53ef\u548c\u80a1\u6743\u6295\u8d44\u3002<\/div>\n
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4. 3\u670810\u65e5\uff0c\u82f1\u56fd\u5251\u6865\u5927\u5b66Ravindra Kumar Gupta\u7b49\u4eba\u5728\u67f3\u53f6\u5200\u5b50\u520a\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u79f0\u5168\u7403\u7b2c\u4e8c\u4f8b\u827e\u6ecb\u75c5\u60a3\u8005\u88ab\u6cbb\u6108\u3002<\/div>\n
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* \u5f80\u671f\u7b80\u62a5\u91cd\u70b9\u5206\u6790\u5df2\u6536\u5f55\u81f3\u300a2020\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b\uff0c\u8be6\u60c5\u6233\u6587\u672b\u8d2d\u4e70\u589e\u8ba2\u7535\u5b50\u7248\u3002<\/div>\n
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01 \u4e00\u6b65\u4e4b\u9065 | \u8bfa\u79be\u81f4\u6e90IPO\u7533\u8bf7\u88ab\u7ec8\u6b62<\/div>\n\n
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3\u670813\u65e5\uff0c\u8bc1\u76d1\u4f1a\u53d1\u884c\u76d1\u7ba1\u90e8\u53d1\u5e03\u7684\u9996\u6b21\u516c\u5f00\u53d1\u884c\u80a1\u7968\u4f01\u4e1a\u57fa\u672c\u4fe1\u606f\u60c5\u51b5\u8868\uff08\u622a\u81f32020\u5e743\u670812\u65e5\uff09\u663e\u793a\uff0c\u8bfa\u79be\u81f4\u6e90IPO\u7533\u8bf7\u57282020\u5e742\u670828\u65e5\u88ab\u7ec8\u6b62\u5ba1\u67e5\u3002\uff08\u8bc1\u76d1\u4f1a\uff09<\/div>\n
\u51fa\u5904\uff1a>>>http:\/\/www.csrc.gov.cn\/pub\/zjhpublic\/G00306202\/201803\/t20180324_335702.htm<\/div>\n
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3\u670815\u65e5\u665a\u95f4\uff0c\u590d\u661f\u533b\u836f\uff08600196.SH\uff1b02196.HK\uff09\u53d1\u5e03\u516c\u544a\u5ba3\u5e03\u8054\u624bmRNA\u7597\u6cd5\u4f01\u4e1aBioNTech\u542f\u52a8\u65b0\u51a0\u75ab\u82d7\u6218\u7565\u5408\u4f5c\u3002\u5373\uff0c\u65d7\u4e0b\u63a7\u80a1\u5b50\u516c\u53f8\u4e0a\u6d77\u590d\u661f\u533b\u836f\u4ea7\u4e1a\u53d1\u5c55\u6709\u9650\u516c\u53f8\u5411BioNTechSE\u652f\u4ed8\u81f3\u591a8,500\u4e07\u7f8e\u5143\u7684\u8bb8\u53ef\u8d39\uff0c\u5e76\u5728\u7ea6\u5b9a\u7684\u9500\u552e\u63d0\u6210\u671f\u95f4\u5185\u6309\u8be5\u4ea7\u54c1\u5e74\u5ea6\u6bdb\u5229\u768435%\u652f\u4ed8\u9500\u552e\u63d0\u6210\uff0c\u5728\u4e2d\u56fd\u72ec\u5bb6\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u57fa\u4e8e\u5176\u4e13\u6709\u7684mRNA\u6280\u672f\u5e73\u53f0\u7814\u53d1\u7684\u9488\u5bf9COVID-19\u7684\u75ab\u82d7\u4ea7\u54c1\uff0c\u540c\u65f6\u5bf9BioNTechSE\u8fdb\u884c\u7ea65,000\u4e07\u7f8e\u5143\u7684\u80a1\u6743\u6295\u8d44\u3002BioNTechSE(NASDAQ:BNTX)\u662f\u5177\u6709\u8f83\u5927\u89c4\u6a21\u7684\u751f\u4ea7\u5236\u9020\u8bbe\u65bd\u7684mRNA\u5e73\u53f0\u578b\u751f\u7269\u6280\u672f\u516c\u53f8\u4e4b\u4e00\uff0c\u4e8e2019\u5e74\u4e0a\u5e02\u3002<\/div>\n
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03 \u56fd\u52a1\u9662 | \u5173\u4e8e\u6df1\u5316\u533b\u7597\u4fdd\u969c\u5236\u5ea6\u6539\u9769\u7684\u610f\u89c1\u53d1\u5e03<\/div>\n\n
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3\u67085\u65e5\uff0c\u300a\u4e2d\u5171\u4e2d\u592e \u56fd\u52a1\u9662\u5173\u4e8e\u6df1\u5316\u533b\u7597\u4fdd\u969c\u5236\u5ea6\u6539\u9769\u7684\u610f\u89c1\u300b\u53d1\u5e03\uff0c\u610f\u89c1\u56f4\u7ed5\u575a\u6301\u548c\u5b8c\u5584\u4e2d\u56fd\u7279\u8272\u793e\u4f1a\u5236\u5ea6\uff0c\u52a0\u5feb\u5efa\u6210\u8986\u76d6\u5168\u6c11\u3001\u57ce\u4e61\u7edf\u7b79\u3001\u6743\u8d23\u6e05\u6670\u3001\u4fdd\u969c\u9002\u5ea6\u3001\u53ef\u6301\u7eed\u7684\u591a\u5c42\u6b21\u533b\u7597\u4fdd\u969c\u4f53\u7cfb\u3002\uff08\u65b0\u534e\u793e\uff09<\/div>\n
\u539f\u6587>>>\u00a0http:\/\/www.gov.cn\/zhengce\/2020-03\/05\/content_5487407.htm \uff08\u590d\u5236\u7f51\u5740\u5230\u6d4f\u89c8\u5668\u67e5\u770b\uff0c\u4e0b\u540c\uff09<\/div>\n
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04 The\u00a0Lancet HIV\u00a0| \u5168\u7403\u7b2c\u4e8c\u4f8b\u827e\u6ecb\u75c5\u60a3\u8005\u88ab\u6cbb\u7597<\/div>\n\n
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\"RmFicvQBAkgB9qFnw1cUBVPRxVr5HoXFCsKo0U0Cicw5Lz5neAcBlpooOM9kWphjia9lYX98R4vKpyN9kAmkj57gA\"\/<\/figure><\/div>\n\n
\u25b3 \u56fe\uff1a\u8bba\u6587\u622a\u56fe\uff08\u6765\u6e90\/The Lancet HIV\u00a0\uff09<\/div>\n
3\u670810\u65e5\uff0cRavindra Kumar Gupta\u56e2\u961f\u5728The Lancet HIV \u53d1\u8868\u7814\u7a76\u8bba\u6587\uff0c\u79f0\u4f26\u6566\u7537\u5b50Adam Castillejo\u6210\u201c\u827e\u6ecb\u75c5\u6cbb\u6108\u201d\u5168\u7403\u7b2c\u4e8c\u4eba\uff0c\u7b2c\u4e00\u4f8b\u6cbb\u6108\u8005\u4e3a2007\u5e74\u7684\u201c\u67cf\u6797\u75c5\u4eba\u201dTimothy Ray Brown\u3002\uff08The Lancet HIV \uff09<\/div>\n
\u539f\u6587>>>\u00a0https:\/\/www.thelancet.com\/journals\/lanhiv\/article\/PIIS2352-3018(20)30069-2\/fulltext<\/div>\n
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05 \u65b0\u51a0\u75c5\u6bd2\u00a0|\u00a0\u4e2d\u65e5\u53cb\u597d\u533b\u9662\u66f9\u5f6c\u6559\u6388\u53d1\u5e03\u65b0\u51a0\u75c5\u6bd2\u81f4\u6b7b\u98ce\u9669\u56e0\u7d20<\/div>\n\n
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\"RmFicvQBAkgB9qFnw1cUBVPRxVr5HoXFCBhDZBicpjge2chfsr99qV5hzbWyoPgGoCHUbVm8rrcWr2sKf1JXicelQ\"\/<\/figure><\/div>\n\n
\u25b3 \u56fe\uff1a\u8bba\u6587\u622a\u56fe\uff08\u6765\u6e90\/The Lancet HIV\u00a0\uff09<\/div>\n
3\u670811\u65e5\uff0c\u4e2d\u65e5\u53cb\u597d\u533b\u9662\u526f\u9662\u957f\u66f9\u5f6c\u6559\u6388\u9886\u8854\u56e2\u961f\u5728The Lancet\u53d1\u8868\u9898\u201cClinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study\u201d\u7684\u8bba\u6587\uff0c\u63ed\u793a\u4e86\u65b0\u51a0\u75c5\u6bd2\u7684\u81f4\u6b7b\u56e0\u7d20\uff1b\u4e14\u8bf4\u660e\u75c5\u6bd2\u53d1\u6325\u6bd2\u6027\u65f6\u957f\u6700\u77ed\u4e3a8\u5929\uff0c\u6700\u957f\u8fbe37\u5929\u3002<\/div>\n
\u539f\u6587>>>\u00a0https:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736(20)30566-3\/fulltext<\/div>\n
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\u5e94\u7528<\/div>\n
06 \u56fd\u5bb6\u836f\u76d1\u5c40\u00a0|\u00a0 \u622a\u6b623\u670814\u65e5\u5171\u8ba119\u4e2a\u65b0\u51a0\u68c0\u6d4b\u8bd5\u5242\u76d2\u83b7\u6279<\/div>\n
3\u670814\u65e5\uff0c\u5357\u4eac\u8bfa\u552f\u8d5e\u548c\u73e0\u6d77\u4e3d\u73e0\u7684IgM \/ IgG\u6297\u4f53\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08\u80f6\u4f53\u91d1\u6cd5\uff09\u83b7\u6279\uff0c\u622a\u6b62\u76ee\u524d\uff0c\u5171\u6709\u6838\u9178\u68c0\u6d4b\u8bd5\u5242\u76d211\u4e2a\uff0c\u6297\u4f53\u68c0\u6d4b\u8bd5\u5242\u76d28\u4e2a\u83b7\u5f97\u56fd\u5bb6\u836f\u54c1\u517c\u987e\u636e\u83b7\u6279\uff0c\u5728\u201c\u57fa\u56e0\u6167\u201d\u516c\u4f17\u53f7\u4e3b\u9875\u56de\u590d\u201c\u65b0\u51a0\u8bd5\u5242\u76d2\u201d\u53ef\u83b7\u5f97\u5217\u8868\u6c47\u603b\u3002\uff08\u56fd\u5bb6\u836f\u76d1\u5c40\uff09<\/div>\n
07 \u884c\u4e1a\u5171\u8bc6 | \u9996\u4e2a\u4e34\u5e8a\u9057\u4f20\u75c5NGS\u57fa\u56e0\u68c0\u6d4b\u5168\u6d41\u7a0b\u5171\u8bc6\u53d1\u5e03<\/a><\/div>\n
\u8fd1\u65e5\uff0c\u300a\u4e2d\u534e\u533b\u5b66\u9057\u4f20\u5b66\u300b\u6742\u5fd7\u540c\u671f\u56db\u7bc7\u520a\u53d1\u4e86\u300a\u9057\u4f20\u75c5\u4e8c\u4ee3\u6d4b\u5e8f\u4e34\u5e8a\u68c0\u6d4b\u5168\u6d41\u7a0b\u89c4\u8303\u5316\u5171\u8bc6\u63a2\u8ba8\u300b\uff0c\u8fd9\u662f\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\uff08\u7b79\u300b\u8054\u5408\u56fd\u5185\u4e34\u5e8a\u4e13\u5bb6\u3001\u9057\u4f20\u5b66\u5bb6\u4ee5\u53ca\u7b2c\u4e09\u65b9\u57fa\u56e0\u68c0\u6d4b\u673a\u6784\uff0c\u57fa\u4e8e\u57fa\u56e0\u79d1\u6280\u53d1\u5c55\u548c\u5b9e\u9645\u5e94\u7528\u573a\u8fbe\u6210\u7684\u7b2c\u4e8c\u9879\u884c\u4e1a\u5171\u8bc6\u3002\u5171\u8bc6\u4ece\u9057\u4f20\u68c0\u6d4b\u524d\u6d41\u7a0b\uff0c\u6837\u54c1\u91c7\u96c6\u5904\u7406\u53ca\u68c0\u6d4b\uff0c\u6570\u636e\u5206\u6790\u6d41\u7a0b\uff0c\u68c0\u6d4b\u62a5\u544a\u89e3\u8bfb\u548c\u9057\u4f20\u54a8\u8be2\u7b49\u65b9\u9762\uff0c\u89c4\u8303\u4e86\u9057\u4f20\u75c5\u57fa\u56e0\u68c0\u6d4b\u5168\u6d41\u7a0b\u3002\uff08\u57fa\u56e0\u6167\uff09<\/div>\n
\u6df1\u5ea6\u5206\u6790\u70b9\u51fb>>>\u00a0\u00a0\u9996\u4e2a\u4e34\u5e8a\u9057\u4f20\u75c5NGS\u57fa\u56e0\u68c0\u6d4b\u5168\u6d41\u7a0b\u5171\u8bc6\u53d1\u5e03<\/a><\/div>\n
\u00a0 \u3010\u7f16\u8005\u6309 \u3011\u00a0<\/div>\n
\u8fd9\u662f\u57fa\u56e0\u6167\u53c2\u4e0e\u7ec4\u7ec7\u7684\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\uff08\u7b79\uff09\u53d1\u5e03\u7684\u7b2c\u4e8c\u7bc7\u884c\u4e1a\u5171\u8bc6\u3002\u867d\u7136\u76ee\u524d\u57fa\u56e0\u884c\u4e1a\u53d1\u5c55\u76f8\u5bf9\u4e50\u89c2\uff0c\u4f46\u6570\u767e\u5bb6\u4f01\u4e1a\u540c\u8d28\u5316\uff08\u4f8b\u5982\u5373\u5c06\u4e0a\u5e02\u7684\u80bf\u7624\u57fa\u56e0\u4f01\u4e1a\uff09\u4e25\u91cd\u4e4b\u5916\u7f3a\u4e4f\u534f\u4f5c\u5e73\u53f0\uff0c\u56e0\u6b64\uff0c\u76ee\u524d\u5c11\u91cf\u7684\u884c\u4e1a\u6807\u51c6\u4ecd\u6709\u9f99\u5934\u4f01\u4e1a\u548c\u79d1\u7814\u673a\u6784\u628a\u6301\uff0c\u4e2d\u5c0f\u4f01\u4e1a\u7f3a\u4e4f\u5165\u573a\u5238\uff0c\u800c\u5927\u4f01\u4e1a\u7684\u6807\u51c6\u4e5f\u8f83\u96be\u63a8\u5e7f\uff0c\u90e8\u5206\u4f01\u4e1a\u53d1\u5e03\u6ca1\u6709\u68c0\u6d4b\u7684\u201c\u7a7a\u5934\u62a5\u544a\u201d\u6216\u5929\u8d4b\u57fa\u56e0\u68c0\u6d4b\u6c61\u67d3\u884c\u4e1a\uff0c\u7f3a\u4e4f\u76d1\u7ba1\u7684\u539f\u56e0\u4e5f\u5305\u62ec\u5171\u8bc6\u548c\u6807\u51c6\u7684\u666e\u53ca\u3002\u56e0\u6b64\u4e2d\u7acb\u3001\u534f\u4f5c\u7684\u7b2c\u4e09\u65b9\u5e73\u53f0\u5c24\u5176\u5173\u952e\uff0c\u8054\u5408\u653f\u4ea7\u5b66\u7814\u7528\u8fbe\u6210\u884c\u4e1a\u5171\u8bc6\u3001\u6807\u51c6\u53ca\u6307\u5357\u662f\u672a\u6765\u8d8b\u52bf\uff0c\u5c24\u5176\u662f\u57fa\u56e0\u884c\u4e1a\u7684\u6280\u672f\u548c\u4ea7\u4e1a\u5fc3\u6001\u4ee5\u6bcf\u4e2a\u6708\u66f4\u65b0\u7684\u901f\u7387\u53d1\u5c55\uff0c\u975e\u4e00\u5bb6\u673a\u6784\u6216\u51e0\u4e2a\u4e13\u5bb6\u53ef\u4ee5\u8986\u76d6\u6240\u6709\u9886\u57df\uff0c\u9700\u8981\u884c\u4e1a\u5404\u65b9\u5171\u540c\u63a8\u5e7f\u3002\u8fd9\u662f\u884c\u4e1a\u53d1\u5c55\u547d\u8109\u548c\u4f7f\u547d\uff0c\u4e5f\u662f\u4ea7\u4e1a\u673a\u4f1a\u4e4b\u4e00\u3002<\/div>\n
\u00a0<\/div>\n
08 \u65b0\u51a0\u75c5\u6bd2\u75ab\u82d7 | \u81f3\u5c11\u970018\u4e2a\u6708\u624d\u80fd\u6295\u5165\u4f7f\u7528<\/div>\n\n
\n
\"RmFicvQBAkgB9qFnw1cUBVPRxVr5HoXFCcA4tUNejy0zKsoR7MwI7GfS7xnSj3bVYNhQ57IJ6PJCkHicoC0LOnXA\"\/<\/figure><\/div>\n\n
\u25b3 \u56fe\uff1a3\u67082\u65e5\uff0c\u7279\u6717\u666e\u548c\u767d\u5bab\u51a0\u72b6\u75c5\u6bd2\u5de5\u4f5c\u7ec4\u6210\u5458\u4e0e\u751f\u7269\u6280\u672f\u516c\u53f8\u4e3e\u884c\u4f1a\u8bae\uff08\u6765\u6e90\/AP\u56fe\u50cf\uff09<\/div>\n
\u8fd1\u65e5\uff0cModerna\u751f\u4ea7\u7684 mRNA\u75ab\u82d7\u662f\u5c06\u9488\u5bf9\u75c5\u6bd2\u6210\u5206\u7684\u9057\u4f20\u5b66\u6307\u4ee4\u5d4c\u5165\u7eb3\u7c73\u9897\u7c92\u4e2d\uff0c\u518d\u6ce8\u5c04\u5230\u4eba\u4f53\u3002\u867d\u8d77\u6b65\u5feb\u4f46\u5176\u75ab\u82d7\u5f00\u53d1\u6280\u672f\u672a\u7ecf\u9a8c\u8bc1\uff0c\u8bc1\u660e\u5b89\u5168\u4e14\u53ef\u4f7f\u4eba\u514d\u53d7\u611f\u67d3\u81f3\u5c11\u970018\u4e2a\u6708\u3002(MIT Technology Review)<\/div>\n
\u539f\u6587>>>\u00a0https:\/\/www.technologyreview.com\/s\/615331\/a-coronavirus-vaccine-will-take-at-least-18-monthsif-it-works-at-all\/<\/div>\n
\u4ea7\u4e1a<\/div>\n
10 BillionToOne | \u5b8c\u62101500\u4e07\u7f8e\u5143A\u8f6e\u540e\u7eed\u878d\u8d44<\/div>\n
\u7f8e\u56fd\u65f6\u95f43\u670810\u65e5\uff0c\u81f4\u529b\u4e8e\u764c\u75c7\u7cbe\u51c6\u8bca\u65ad\u68c0\u6d4b\u7684BillionToOne\u5ba3\u5e03\uff0c\u5b8c\u62101500\u4e07\u7f8e\u5143A\u8f6e\u540e\u7eed\u878d\u8d44\uff0c\u672c\u8f6e\u878d\u8d44\u7531Hummingbird Ventures\u548cNeoTribe Ventures\u9886\u6295\uff0cY Combinator\uff0cLibertus Capital\uff0cPacific 8 Ventures\uff0cCivilization Ventures\uff0c500 Startups Istanbul\u548cHOF Capital\u8ddf\u6295\u3002\uff08Genomeweb\uff09<\/div>\n
\u539f\u6587>>>\u00a0https:\/\/www.genomeweb.com\/business-news\/billiontoone-closes-15m-series-follow-round#.XmpAbIj7RPY<\/div>\n
09 \u6d3e\u771f\u751f\u7269 | \u5b8c\u6210\u5343\u4e07\u7ea7A\u8f6e\u878d\u8d44<\/div>\n
3\u670811\u65e5\uff0c\u57fa\u56e0\u836f\u7269\u4ea7\u4e1a\u5316\u5e73\u53f0\u5e7f\u5dde\u6d3e\u771f\u751f\u7269\u6280\u672f\u6709\u9650\u516c\u53f8\uff0c\u5ba3\u5e03\u5df2\u57282\u6708\u5b8c\u6210\u5343\u4e07\u7ea7A\u8f6e\u878d\u8d44\uff0c\u672c\u8f6e\u6295\u8d44\u7531\u817e\u4e1a\u521b\u6295\u6295\u8d44\u3002\u503c\u5f97\u5173\u6ce8\u7684\u662f\uff0c\u6d3e\u771f\u751f\u7269\u53d7\u5e7f\u4e1c\u7701\u518d\u751f\u533b\u5b66\u91cd\u70b9\u5b9e\u9a8c\u5ba4\uff0c\u949f\u5357\u5c71\u9662\u58eb\u56e2\u961f\u7b49\u56db\u5bb6\u79d1\u7814\u673a\u6784\u7684\u59d4\u6258\uff0c\u627f\u62c5\u75ab\u82d7\u548c\u836f\u7269\u5f00\u53d1\u8fc7\u7a0b\u4e2d\u7684AAV\u8f7d\u4f53\u8bbe\u8ba1\u3001\u6784\u5efa\u548c\u75c5\u6bd2\u751f\u4ea7\u73af\u8282\u3002(\u6d3e\u771f\u751f\u7269\uff09<\/div>\n
\u6218\u75ab\u7279\u522b\u62a5\u9053<\/div>\n
\u00a0<\/div>\n
10 \u89c6\u9891 | \u949f\u5357\u5c71\u5e94\u9080\u5411\u6b27\u6d32\u540c\u4ec1\u5168\u65b9\u4f4d\u89e3\u6790\u65b0\u51a0\u80ba\u708e<\/div>\n