{"id":9116,"date":"2020-04-13T03:00:59","date_gmt":"2020-04-12T19:00:59","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100013116&idx=1&sn=fa52c784faca766b59303141168b757f&chksm=6b71468b5c06cf9dcb614bee8f82012d98dd47757c53b2f8282a01a916f292bdcc3c4ee4e231#rd"},"modified":"2026-04-02T10:06:08","modified_gmt":"2026-04-02T02:06:08","slug":"545351","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2020\/04\/13\/545351\/","title":{"rendered":"\u57fa\u56e0\u7b80\u62a5 | \u4e2d\u7f8e58\u4e2a\u65b0\u51a0\u68c0\u6d4b\u4ea7\u54c1\u83b7\u6279\uff0c\u4e24\u54688\u8d77\u878d\u8d44\uff0cQ1\u8d22\u62a5\u9884\u544a"},"content":{"rendered":"
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4\uff094\u67084\u65e5\uff0c\u81f4\u529b\u4e8e\u9776\u5411RNA\u836f\u7269\u5f00\u53d1\u7684Rgenta\u00a0Therapeutics\uff0c\u5ba3\u5e03\u5b8c\u62102000\u4e07\u7f8e\u5143\u79cd\u5b50\u8f6e\u878d\u8d44\u3002\u672c\u8f6e\u878d\u8d44\u7531\u7ecf\u7eac\u4e2d\u56fd\u3001Boehringer Ingelheim Venture Fund\u9886\u6295\uff0c\u51ef\u6cf0\u8d44\u672c\u3001\u8054\u60f3\u4e4b\u661f\u8ddf\u6295\u3002\uff08\u7ecf\u7eac\u521b\u6295\uff09<\/div>\n
5\uff094\u67083\u65e5\uff0c\u805a\u7126\u80bf\u7624\u7cbe\u51c6\u8bca\u7597\u7684\u6d77\u666e\u6d1b\u65af\uff0c\u5ba3\u5e03\u5b8c\u6210\u6570\u5343\u4e07\u5143B+\u8f6e\u878d\u8d44\uff0c\u672c\u8f6e\u878d\u8d44\u7531\u8fdc\u81f4\u521b\u6295\u6295\u8d44\u3002\uff08\u6d77\u666e\u6d1b\u65afHaploX\uff09<\/div>\n
6\uff094\u67083\u65e5\uff0c\u81f4\u529b\u4e8e\u5c0f\u6838\u9178\u836f\u7269\u7814\u7a76\u548c\u5f00\u53d1\u7684\u82cf\u5dde\u745e\u535a\u751f\u7269\u6280\u672f\u6709\u9650\u516c\u53f8\uff0c\u5ba3\u5e03\u5b8c\u62104.7\u4ebf\u5143C2\u8f6e\u878d\u8d44\u3002\u672c\u8f6e\u878d\u8d44\u7531\u4e2d\u56fd\u56fd\u6709\u8d44\u672c\u98ce\u9669\u6295\u8d44\u57fa\u91d1\u9886\u6295\uff0c\u4e2d\u91d1\u542f\u5fb7\u57fa\u91d1\u3001\u9ad8\u74f4\u521b\u6295\u8054\u5408\u9886\u6295\uff0c\u6052\u65ed\u8d44\u672c\u3001\u6717\u739b\u5cf0\u521b\u6295\u7b49\u8ddf\u6295\u3002\uff08\u52a8\u8109\u65b0\u533b\u836f\uff09<\/div>\n
7\uff094\u67081\u65e5\uff0c\u57fa\u56e0\u7597\u6cd5\u516c\u53f8Affinia Therapeutics\u5ba3\u5e03\u5b8c\u62106000\u4e07\u7f8e\u5143A\u8f6e\u878d\u8d44\uff0c\u672c\u8f6e\u878d\u8d44\u7531Atlas Venture\u9886\u6295\u3002\uff08\u521b\u9274\u6c47\uff09<\/div>\n
8\uff093\u670825\u65e5\uff0c\u5409\u51ef\u57fa\u56e0\u533b\u5b66\u79d1\u6280\u80a1\u4efd\u6709\u9650\u516c\u53f8\u5ba3\u5e03\u5b8c\u6210C\u8f6e\u8fd14\u4ebf\u5143\u878d\u8d44\u3002\u672c\u8f6e\u878d\u8d44\u65b0\u5f15\u8fdb\u6295\u8d44\u65b9\u6709\u6b66\u6c49\u4eba\u798f\u751f\u7269\u533b\u836f\u4ea7\u4e1a\u6295\u8d44\u57fa\u91d1\u4e2d\u5fc3\uff08\u6709\u9650\u5408\u4f19\uff09\u3001\u4e0a\u6d77\u5f20\u6c5f\u79d1\u6280\u521b\u4e1a\u6295\u8d44\u6709\u9650\u516c\u53f8\u7b49\u3002\uff08\u5409\u51ef\u57fa\u56e0\u8f6c\u5316\u533b\u5b66\u5e73\u53f0\uff09<\/div>\n
\uff08\u66f4\u591a\u878d\u8d44\u6570\u636e\u89c1\u57fa\u56e0\u6167\u65d7\u4e0bYourMap\u5e73\u53f0\uff1awww.yourmap.net.cn\uff09<\/div>\n
\u00a0<\/div>\n
\u8d22\u62a5 | \u57fa\u56e0\u4f01\u4e1aQ1\u8d22\u62a5\u9884\u544a\u4e24\u6781\u5316<\/div>\n
\u6839\u636e\u4f01\u4e1a\u5b98\u65b9\u516c\u544a\uff0c\u534e\u5927\u57fa\u56e0\u7b2c\u4e00\u5b63\u5ea6\u56e0\u611f\u67d3\u9632\u63a7\u4e1a\u52a1\u7684\u9ad8\u901f\u589e\u957f\uff0c\u6574\u4f53\u8425\u4e1a\u6536\u5165\u9884\u8ba1\u8f83\u4e0a\u5e74\u540c\u671f\u589e\u957f\u7ea6 30%-40%\uff0c\u5f52\u5c5e\u4e8e\u4e0a\u5e02\u516c\u53f8\u80a1\u4e1c\u7684\u51c0\u5229\u6da6\uff08\u7b80\u79f0\u201c\u51c0\u5229\u6da6\u201d\uff09\u540c\u6bd4\u589e\u957f35%-45%\u3002<\/div>\n
\u8d1d\u745e\u57fa\u56e0\u51fa\u8ba9\u5b59\u516c\u53f8\u96c5\u58eb\u80fd\u57fa\u56e0\u79d1\u6280\u6709\u9650\u516c\u53f8\u7684\u63a7\u80a1\u5b50\u516c\u53f8\u5584\u89c5\u63a7\u80a1\u6709\u9650\u516c\u53f8\u53ca\u5176\u63a7\u80a1\u5b50\u516c\u53f8\u7684\u63a7\u5236\u6743\uff08\u9884\u671f\u4ea7\u751f\u5229\u6da6\u7ea69,200\u4e07\u5143\u20149,700 \u4e07\u5143\uff09\uff0c\u7b2c\u4e00\u5b63\u5ea6\u9884\u8ba1\u76c8\u5229\u540c\u6bd4\u589e\u957f147%-170%\uff0c\u537316,200 \u4e07\u5143-17,700 \u4e07\u5143\uff0cEPS\u9884\u8ba1\u4e3a0.4568 \u5143-0.4991 \u5143\u3002<\/div>\n
\u867d\u7136\u4e0d\u662f\u5b8c\u5168\u5bf9\u6807\uff0c\u4f46\u5bf9\u6bd4\u5176\u4ed6\u5206\u5b50\u8bca\u65ad\u516c\u53f8\u7684\u6570\u636e\u53ef\u4ee5\u770b\u51fa\u57fa\u56e0\u4f01\u4e1a\u7684\u6280\u672f\u548c\u653f\u7b56\u4f18\u52bf\u3002\u6839\u636e2020\u5e74\u516c\u544a\u663e\u793a\uff0c\u8fea\u5b89\u8bca\u65ad\u5728Q1\u7684\u51c0\u5229\u6da6\u9884\u8ba1\u4e0b\u964d88%-95%\uff1b\u827e\u5fb7\u751f\u7269\u7684Q1\u8425\u4e1a\u989d\u9884\u8ba1\u540c\u6bd4\u4e0b\u964d26%-20%\uff0c\u51c0\u5229\u6da6\u9884\u8ba1\u540c\u6bd4\u4e0b\u964d23%-17%\u3002<\/div>\n
\u53d7\u75ab\u60c5\u5f71\u54cd\uff0c\u6d77\u5916\u4f01\u4e1a\u8d22\u62a5\u62ab\u9732\u5ef6\u8fdf\u3002Illumina\uff08NASDAQ:ILMN)\u5c06\u57284\u670823\u65e5\u516c\u5e03Q1\u8d22\u62a5\uff0c\u636e\u5206\u6790\u5e08\u9884\u6d4bQ1\u7684EPS\u7ea6\u4e3a1.33\u7f8e\u5143\uff0c\u540c\u6bd4\u4e0b\u964d22%\uff1bQIAGEN\u53d1\u5e03\u516c\u544a\u79f0\u4e0e2020\u5e742\u67084\u65e5\u53d1\u5e03\u7684\u7b2c\u4e00\u5b63\u5ea6\u5c55\u671b\u76f8\u6bd4\u51c0\u9500\u552e\u989d\u589e\u957f\u7ea69\uff05\uff0cEPS\u4e3a0.34-0.35\u7f8e\u5143\uff1bThermo Fisher\u9884\u4f30Q1\u8425\u6536\u540c\u6bd4\u589e\u957f\u57281-2\uff05\u7684\u8303\u56f4\u5185\uff0c\u5e76\u8868\u793a\u5728\u4e09\u6708\u4e0b\u65ec\u5ba2\u6237\u7684\u6d3b\u8dc3\u6027\u663e\u8457\u51cf\u5c0f\u3002<\/div>\n
\u00a0<\/div>\n
\u3010\u7f16\u8005\u6309\u3011\u57fa\u56e0\u884c\u4e1a\u7684\u653f\u7b56\u7ea2\u5229\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u6e90\u4e8e\u6280\u672f\u7684\u4f18\u52bf\uff0c\u4e0b\u4e00\u4ee3\u6d4b\u5e8f\/RT-PCR\u533a\u522b\u4e8e\u5176\u4ed6\u5206\u5b50\u8bca\u65ad\u7684\u672c\u8d28\u662f\uff1a\u9ad8\u901a\u91cf\u6570\u5b57\u5316\uff0c\u8fd9\u4e0d\u4ec5\u5e26\u6765\u6210\u672c\u4f18\u52bf\uff0c\u4e5f\u5fc5\u5c06\u968f\u7740\u6837\u672c\u79ef\u7d2f\u5e26\u7740\u6570\u636e\u89c4\u6a21\u6548\u5e94\u2014\u2014\u4e3a\u516c\u5171\u536b\u751f\u53ca\u66f4\u591a\u5e94\u7528\u7684\u9884\u6d4b\u9884\u9632\u76d1\u6d4b\u7b5b\u67e5\u63d0\u4f9b\u5927\u6570\u636e\u8981\u7d20\uff1b\u540c\u65f6\u5e26\u6765\u5784\u65ad\u6548\u5e94\u3002<\/div>\n
\u800c\u53d7\u6d77\u5916\u75ab\u60c5\u5f71\u54cd\u53ca\u6211\u56fd\u5f00\u653e\u653f\u7b56\uff0c\u53ef\u4ee5\u9884\u8ba1\u5305\u62ecILMN\u3001ONT\u3001TMO\u7b49\u6d77\u5916\u57fa\u56e0\u4f01\u4e1a\u5c06\u52a0\u5927\u5728\u6211\u56fd\u672c\u571f\u5316\uff0c\u540c\u65f6\u6211\u56fd\u5373\u5c06\u51fa\u53f0\u300a\u751f\u7269\u5b89\u5168\u6cd5\u300b\uff0c\u8fd9\u4f7f\u5f97\u62db\u5546\u3001\u5e76\u8d2d\u53ca\u5408\u4f5c\u8fdb\u5165\u5fae\u5999\u65f6\u671f\uff0c\u5c24\u5176\u662f\u5404\u5927\u56ed\u533a\u9700\u5236\u5b9a\u975e\u5e38\u89c4\u7b56\u7565\u6765\u5e73\u8861\u4e8c\u8005\uff08\u6b22\u8fce\u8054\u7edc\u57fa\u56e0\u6167\u5408\u4f5c\u4ea7\u4e1a\u89c4\u5212\u3001\u5e76\u8d2d\u884c\u7814\u3001\u62db\u5546\u62a5\u544a\u670d\u52a1\uff09\u3002<\/div>\n
\u00a0<\/div>\n
\u653f\u7b56<\/div>\n
\u56fd\u52a1\u9662 | \u63a8\u52a8\u8981\u7d20\u5e02\u573a\u5316\u914d\u7f6e\u4f53\u5236\u673a\u5236<\/div>\n
4\u67089\u65e5\uff0c\u4e3a\u6df1\u5316\u8981\u7d20\u5e02\u573a\u5316\u914d\u7f6e\u6539\u9769\uff0c\u8fdb\u4e00\u6b65\u6fc0\u53d1\u5168\u793e\u4f1a\u521b\u9020\u529b\u548c\u5e02\u573a\u6d3b\u529b\uff0c\u63a8\u52a8\u7ecf\u6d4e\u53d8\u9769\uff0c\u4e2d\u5171\u4e2d\u592e\u56fd\u52a1\u9662\u53d1\u5e03\u300a\u5173\u4e8e\u6784\u5efa\u66f4\u52a0\u5b8c\u5584\u7684\u8981\u7d20\u5e02\u573a\u5316\u914d\u7f6e\u4f53\u5236\u673a\u5236\u7684\u610f\u89c1\u300b\u3002\u5176\u4e2d\u7684\u8981\u7d20\u5e02\u573a\u5305\u62ec\u571f\u5730\u3001\u52b3\u52a8\u529b\u3001\u8d44\u672c\u3001\u6280\u672f\u3001\u6570\u636e\u7b49\u7b49\u3002<\/div>\n
\u539f\u6587\u89c1 >>><\/div>\n
http:\/\/www.gov.cn\/zhengce\/2020-04\/09\/content_5500622.htm<\/div>\n
\u3010\u7f16\u8005\u6309\u3011\u8fd9\u4efd\u6587\u4ef6\u6709\u8bf8\u591a\u4eae\u70b9\uff0c\u4f8b\u5982\uff1a1\uff09\u6570\u636e\u88ab\u4f5c\u4e3a\u548c\u571f\u5730\u3001\u52b3\u52a8\u529b\u3001\u8d44\u672c\u3001\u6280\u672f\u5e76\u5217\u7684\u5e02\u573a\u8981\u7d20\uff1b2\uff09\u9f13\u52b1\u6570\u636e\u4ea4\u6613\uff08\u4ee5\u53ca\u53ef\u80fd\u7684\u77e5\u8bc6\u4ea7\u6743\u4ea4\u6613\uff09\uff1b3\uff09\u9f13\u52b1\u79bb\u5cb8\u53cc\u521b\u3001\u8fdb\u4e00\u6b65\u63a5\u7eb3\u5916\u8d44\u548c\u5916\u7c4d\u521b\u4e1a\u8005\u548c\u79d1\u5b66\u5bb6\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u79d1\u6280\u90e8 |\u00a0\u5f15\u5bfc\u7ec4\u7ec7\u79d1\u7814\u9662\u6821\u4e0e\u4f01\u4e1a\u5171\u5efa\u8054\u5408\u5b9e\u9a8c\u5ba4\u7b49<\/div>\n
4\u67087\u65e5\uff0c\u79d1\u6280\u90e8\u529e\u516c\u5385\u53d1\u5e03\u300a\u5173\u4e8e\u5f00\u5c55\u79d1\u6280\u4eba\u5458\u670d\u52a1\u4f01\u4e1a\u4e13\u9879\u884c\u52a8\u901a\u77e5\u300b\uff0c\u901a\u8fc7\u5f15\u5bfc\u7ec4\u7ec7\u79d1\u7814\u9662\u6240\u3001\u9ad8\u6821\u4e0e\u4f01\u4e1a\u5171\u5efa\u65b0\u578b\u7814\u53d1\u673a\u6784\u3001\u8bbe\u7acb\u8054\u5408\u5b9e\u9a8c\u5ba4\u7b49\uff0c\u4e3a\u4f01\u4e1a\u6297\u51fb\u75ab\u60c5\u3001\u590d\u5de5\u590d\u4ea7\u3001\u6301\u7eed\u53d1\u5c55\u63d0\u4f9b\u79d1\u6280\u548c\u667a\u529b\u652f\u6491\u3002<\/div>\n
\u539f\u6587\u89c1>>>http:\/\/www.nmpa.gov.cn\/WS04\/CL2470\/376391.html<\/div>\n
\u3010\u7f16\u8005\u6309\u3011\u7ecf\u6d4e\u53d1\u5c55\u7684\u672c\u8d28\u662f\u52a0\u5f3a\u8d27\u5e01\u7684\u5b9e\u8d28\u6027\u6d41\u52a8\uff0c\u79d1\u6280\u53d1\u5c55\u7684\u672c\u8d28\u52a0\u5f3a\u4fe1\u606f\u7684\u5b9e\u8d28\u6027\u6d41\u52a8\u3002\u8fd9\u4efd\u6587\u4ef6\u5bf9\u4e8e\u5934\u90e8\u4f01\u4e1a\u662f\u653f\u7b56\u7ea2\u5229\uff0c\u540c\u65f6\u4e5f\u8fdb\u4e00\u6b65\u5e26\u52a8\u79d1\u5b66\u5bb6\u521b\u4e1a\uff0c\u7531\u6b64\u5e26\u6765\u7684\u5229\u5f0a\u660e\u663e\uff1a\u63d0\u9ad8\u57fa\u7840\u8f6c\u5316\u6548\u7387\u548c\u6548\u7387\u6269\u5927\u79d1\u6280\u670d\u52a1\u5e02\u573a\u3001\u589e\u52a0\u56e0\u7f3a\u4e4f\u804c\u4e1a\u7ba1\u7406\u5e26\u6765\u7684\u65e9\u671f\u79d1\u7814\u5408\u4f5c\/\u5408\u8d44\u4f01\u4e1a\u7684\u201c\u70e7\u94b1\u201d\u6210\u672c\u3002<\/div>\n
\u519c\u4e1a\u519c\u6751\u90e8 | \u53d1\u5e03\u300a\u56fd\u5bb6\u755c\u79bd\u9057\u4f20\u8d44\u6e90\u76ee\u5f55\u300b\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09<\/div>\n
4\u67088\u65e5\uff0c\u519c\u4e1a\u519c\u6751\u90e8\u516c\u5e03\u300a\u56fd\u5bb6\u755c\u79bd\u9057\u4f20\u8d44\u6e90\u76ee\u5f55\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b\uff0c\u6db5\u76d6\u4e86\u5bb6\u517b\u7684\u4f20\u7edf\u755c\u79bd\u548c\u7279\u79cd\u755c\u79bd\u517131\u4e2a\u79cd\uff0c\u88ab\u5217\u5165\u7684\u52a8\u7269\u5c06\u6309\u7167\u5bb6\u755c\u5bb6\u79bd\u8fdb\u884c\u7ba1\u7406\uff0c\u53ef\u7528\u4e8e\u98df\u7528\u7b49\u5546\u4e1a\u5229\u7528\u3002\u5f81\u6c42\u610f\u89c1\u4e3a\u671f\u4e00\u4e2a\u6708\uff0c\u610f\u89c1\u53cd\u9988\u622a\u6b62\u52302020\u5e745\u67088\u65e5\u3002<\/div>\n
\u539f\u6587\u89c1\uff08\u590d\u5236\u7f51\u5740\u5230\u6d4f\u89c8\u5668\u67e5\u770b\uff0c\u4e0b\u540c\uff09>>><\/div>\n
http:\/\/www.moa.gov.cn\/hd\/zqyj\/202004\/t20200408_6341067.htm<\/div>\n
\u3010\u7f16\u8005\u6309\u3011\u81ea\u7136\u754c\u7684\u65b0\u51a0\u75c5\u6bd2\u7684\u5168\u7403\u6027\u5927\u6d41\u884c\uff0c\u4e0d\u4ec5\u91cd\u65b0\u63d0\u9ad8\u4e86\u533b\u7597\u5065\u5eb7\u548c\u516c\u5171\u536b\u751f\u7684\u91cd\u8981\u6027\uff0c\u91cd\u5851\u4e86\u751f\u4ea7\u5173\u7cfb\uff0c\u5b9e\u73b0\u5728\u7ebf\u5316\u3001\u65e0\u63a5\u89e6\u5f0f\u7b49\u751f\u4ea7\u6a21\u5f0f\uff0c\u4e5f\u5bf9\u91ce\u751f\u52a8\u7269\u7684\u517b\u6b96\u3001\u9910\u996e\u7b49\u5e02\u573a\u884c\u4e3a\u8fdb\u884c\u4e86\u7ea2\u7ebf\u754c\u5b9a\u3002\u8fd9\u4efd\u6587\u4ef6\u5bf9\u4e8e\u8bf8\u591a\u517b\u6b96\u573a\u4e3b\u610f\u4e49\u91cd\u5927\u3002<\/div>\n
\u7279\u522b\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u519c\u4e1a\u519c\u6751\u90e8\u5728\u8bf4\u660e\u4e2d\u56de\u5e94\uff0c\u968f\u7740\u4eba\u7c7b\u6587\u660e\u8fdb\u6b65\u548c\u516c\u4f17\u5bf9\u52a8\u7269\u4fdd\u62a4\u7684\u5173\u6ce8\u53ca\u504f\u7231\uff0c\u72d7\u5df2\u4ece\u4f20\u7edf\u5bb6\u755c\u201c\u7279\u5316\u201d\u4e3a\u4f34\u4fa3\u52a8\u7269\uff0c\u56fd\u9645\u4e0a\u666e\u904d\u4e0d\u4f5c\u4e3a\u755c\u79bd\uff0c\u6211\u56fd\u4e0d\u5b9c\u5217\u5165\u755c\u79bd\u7ba1\u7406\u3002<\/div>\n
\u00a0<\/div>\n
\u4e2d\u68c0\u9662\u00a0| \u5f81\u96c6\u533a\u5757\u94fe\u6280\u672fBRCA\u57fa\u56e0\u7a81\u53d8\u6570\u636e\u548c\u4e13\u5bb6<\/div>\n
\u57fa\u56e0\u61674\u67082\u65e5\u8baf\uff0c\u4e2d\u56fd\u836f\u54c1\u98df\u54c1\u68c0\u5b9a\u7814\u7a76\u9662\u516c\u5f00\u5f81\u96c6\u57fa\u4e8e\u533a\u5757\u94fe\u6280\u672fBRCA\u57fa\u56e0\u7a81\u53d8\u6570\u636e\u548c\u6570\u636e\u5e93\u53d8\u5f02\u89e3\u8bfb\u4e13\u5bb6\u3002<\/div>\n
\u5177\u4f53\u89c1>>><\/div>\n
https:\/\/www.nifdc.org.cn\/nifdc\/ggtzh\/tongzh\/tzh2020\/20200402155400489.html?from=timeline&isappinstalled=0<\/div>\n
\u3010\u7f16\u8005\u6309\u30112017\u5e74\uff0c\u4e73\u817a\u764c\u5375\u5de2\u764cBRCA1\u30012\u57fa\u56e0\u68c0\u6d4b\u7eb3\u5165NCCN\u6307\u5357\uff1b\u540c\u5e74\uff0c\u4e2d\u534e\u533b\u5b66\u4f1a\u75c5\u7406\u5b66\u5206\u4f1a\u7279\u7ec4\u7ec7\u56fd\u5185\u5206\u5b50\u75c5\u7406\u5b66\u9886\u57df\u7684\u76f8\u5173\u4e13\u5bb6\u8ba8\u8bba\u5f62\u6210BRCA\u57fa\u56e0\u68c0\u6d4b\u6d41\u7a0b\u5171\u8bc6\uff1b<\/div>\n
2018\u5e748\u6708\uff0c\u7531\u4e2d\u56fd\u533b\u7597\u5668\u68b0\u884c\u4e1a\u534f\u4f1a\u4e3b\u529e\u7684\u201cNGS BRCA\u6821\u51c6\u8ba1\u5212\u201d\u9879\u76ee\u542f\u52a8\uff0c\u4f1a\u8bae\u8fd8\u5f97\u5230\u4e86\u963f\u65af\u5229\u5eb7\u3001\u9ed8\u6c99\u4e1c\u3001\u8d5b\u9ed8\u98de\u4e16\u5c14\u3001Illumina\u7b49\u516c\u53f8\u7684\u4e2d\u56fd\u5206\u516c\u53f8\u7684\u5171\u540c\u652f\u6301\u3002<\/div>\n
\u7ed3\u5408\u8fd9\u4efd\u65b0\u95fb\uff0c\u53ef\u4ee5\u9884\u6d4b\u957f\u4e45\u4ee5\u6765\u7684\u6570\u636e\u5e93\u6807\u51c6\u5316\u53ca\u5171\u4eab\u548c\u4e2d\u56fd\u4eba\u7fa4\u9776\u5411\u836f\u7269\u53ef\u80fd\u4eceBRCA\u5f00\u59cb\u3002<\/div>\n
\u00a0<\/div>\n
\u79d1\u7814<\/div>\n
TLCR\u00a0| \u4e2d\u56fd\u9996\u4e2aNSCLC ctDNA\u5927\u578b\u771f\u5b9e\u4e16\u754c\u7814\u7a76<\/div>\n
\u4e0a\u6d77\u5e02\u80f8\u79d1\u533b\u9662\u9646\u821c\u3001\u4e1c\u90e8\u6218\u533a\u603b\u9662\u5b8b\u52c7\u3001\u4e2d\u5357\u5927\u5b66\u6e58\u96c5\u533b\u9662\u80e1\u6210\u5e73\u53ca\u5e7f\u5dde\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662\u8c22\u5c55\u9e3f\u8054\u5408\u7ec4\u7ec7\u4e86\u4e2d\u56fd\u9996\u4e2a\u5173\u4e8e\u201c\u63a2\u7d22ctDNA\u52a8\u6001\u76d1\u63a7\u5728NSCLC\u4e34\u5e8a\u6cbb\u7597\u4e2d\u7684\u5e94\u7528\u4ef7\u503c\u201d\u7684\u591a\u4e2d\u5fc3\u3001\u524d\u77bb\u6027\u771f\u5b9e\u4e16\u754c\u7814\u7a76\uff0c\u8bc1\u5b9ectDNA\u53ef\u9884\u6d4b\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u9884\u540e\u3002\u6210\u679c\u4e8e\u8fd1\u65e5\u53d1\u8868\u5728Translational Lung Cancer Research\u4e0a\uff08IF\uff1a4.806\uff09\u3002<\/div>\n
\u6587\u732ePDF\uff08\u5982\u60a8\u5df2\u6ce8\u518cYourMap\uff0c\u53ef\u76f4\u63a5\u4e0b\u8f7d\uff09>>><\/div>\n
http:\/\/www.yourmap.net.cn\/mobile\/download_pdf?doc=1586623572.pdf<\/div>\n
\u00a0<\/div>\n
Cell | \u57fa\u56e0\u7f16\u8f91\u8ba9\u6c38\u4e45\u6027\u89c6\u529b\u635f\u4f24\u7684\u6a21\u578b\u5c0f\u9f20\u91cd\u5efa<\/div>\n
4\u67088\u65e5\uff0c\u4e2d\u79d1\u9662\u8111\u667a\u5353\u8d8a\u4e2d\u5fc3\u6768\u8f89\u56e2\u961f\u3001\u8f89\u5927\u57fa\u56e0CTO\u65bd\u9716\u5b87\u7b49\u5728Cell\u4e0a\u53d1\u8868\u4e86\u9898\u4e3aGlia-to-Neuron Conversion by CRISPR-CasRx Alleviates Symptoms of Neurological Disease in Mice\u7684\u6587\u7ae0\u3002\u7814\u7a76\u901a\u8fc7RNA\u9776\u5411CRISPR\u7cfb\u7edfCasRx\u9996\u6b21\u5728\u6210\u4f53\u4e2d\u5b9e\u73b0\u4e86\u89c6\u795e\u7ecf\u8282\u7ec6\u80de\u518d\u751f\u5e76\u6062\u590d\u4e86\u6c38\u4e45\u6027\u89c6\u529b\u635f\u4f24\u6a21\u578b\u5c0f\u9f20\u7684\u89c6\u529b\u3002\uff08\u8f89\u5927\u751f\u7269\uff09<\/div>\n
\u6df1\u5ea6\u5206\u6790\u70b9\u51fb>>><\/div>\n
\u4e13\u5bb6\u70b9\u8bc4Cell\u4e28\u6768\u8f89\/\u5468\u6d77\u6ce2\u7b49\u5229\u7528CasRx\u5728\u795e\u7ecf\u6027\u75be\u75c5\u6cbb\u7597\u9886\u57df\u53d6\u5f97\u91cd\u5927\u8fdb\u5c55<\/a><\/div>\n
\u3010\u7f16\u8005\u6309\u3011\u57fa\u56e0\u7f16\u8f91\u7684\u80ce\u513f\u4e8b\u4ef6\u4f7f\u5f97\u8fd9\u4e2a\u9886\u57df\u906d\u9047\u201c\u4e00\u5200\u5207\u201d\uff0c\u540c\u65f6\uff0c\u5bf9\u4e8e\u6210\u4f53\u7ec6\u80de\u7684\u57fa\u56e0\u7f16\u8f91\uff0c\u5728\u89c6\u529b\u635f\u4f24\u3001\u5730\u8d2b\u7b49\u9057\u4f20\u5b66\u75be\u75c5\u65b9\u9762\u6709\u91cd\u5927\u5e94\u7528\u3002\u4e16\u754c\u9996\u9879\u6210\u4eba\u4f53\u5185CRISPR\u57fa\u56e0\u7f16\u8f91\u4e34\u5e8a\u8bd5\u9a8c\u5b8c\u6210\u7b2c\u4e00\u4f8b\u60a3\u8005\u7ed9\u836f\uff0c\u5373\u77e5\u540d\u534e\u4eba\u79d1\u5b66\u5bb6\u5f20\u5cf0\u521b\u7acb\u7684Editas Medicine\u516c\u53f8\u5728\u540d\u4e3aBrilliance\u76841\/2\u671f\u4e34\u5e8a\u8bd5\u9a8c\u5df2\u5b8c\u6210\u9996\u4f8bLeber\u5148\u5929\u6027\u9ed1\u672610\uff08LCA10\uff09\u60a3\u8005\u7ed9\u836f\u3002<\/div>\n
\u00a0<\/div>\n
Scientific Data | \u8fc4\u4eca\u6700\u5168\u6700\u7cbe\u7ec6\u7684\u4e9a\u6d32\u7a3b\u57fa\u56e0\u56fe\u8c31<\/div>\n
4\u67087\u65e5\uff0cScientific Data\u00a0\u5728\u7ebf\u520a\u767b\u4e86\u534e\u4e2d\u519c\u4e1a\u5927\u5b66\u5f20\u5efa\u4f1f\u6559\u6388\u53ca\u5176\u5408\u4f5c\u56e2\u961f\u7814\u7a76\u6210\u679c\uff0c\u8be5\u7814\u7a76\u5229\u7528PacBio\u6d4b\u5e8f\u6280\u672f\uff0c\u7ed3\u5408Bionano\u56fe\u8c31\uff0c\u6784\u5efa\u4e86\u8fc4\u4eca\u6700\u5168\u6700\u7cbe\u7ec6\u7684\u4e9a\u6d32\u7a3b\u57fa\u56e0\u56fe\u8c31\u3002\uff08Scientific Data\uff09<\/div>\n
\u539f\u6587\u89c1>>><\/div>\n
https:\/\/www.scilit.net\/article\/9b34d7d77c99db368cf406b99998ed3f<\/div>\n
\u00a0<\/div>\n
Neuron | \u4e3a\u4ec0\u4e48\u81ea\u95ed\u75c7\u7537\u5b69\u591a\u4e8e\u5973\u5b69\uff1f\u5355\u57fa\u56e0NLGN4\u7a81\u53d8\u63d0\u4f9b\u7ebf\u7d22<\/div>\n
4\u67082\u65e5\uff0c\u7f8e\u56fd\u56fd\u5bb6\u795e\u7ecf\u75be\u75c5\u4e0e\u4e2d\u98ce\u7814\u7a76\u6240\u56e2\u961f\u53d1\u73b0NLGN4\u7a81\u53d8\u5bfc\u81f4\u5355\u4e2a\u6c28\u57fa\u9178\u6539\u53d8\uff0c\u53ef\u80fd\u63ed\u793a\u4e3a\u4ec0\u4e48\u81ea\u95ed\u75c7\u60a3\u8005\u4e2d\u7537\u5b69\u591a\u4e8e\u5973\u5b69\uff1f\u7814\u7a76\u6210\u679c\u53d1\u8868\u4e8eNeuron\u3002<\/div>\n
\u8bba\u6587\u51fa\u5904>>>DOI: 10.1016\/j.neuron.2020.03.008<\/div>\n
\u5176\u4ed6\u7cbe\u9009\u79d1\u6280\u524d\u6cbf\u6587\u732e\u25bc<\/div>\n
\u2460 Grail\u7684\u7532\u57fa\u5316\u6d4b\u5e8f\u68c0\u6d4b\u8d85\u8fc750\u79cd\u764c\u75c7<\/div>\n
\u8bba\u6587\u51fa\u5904>>>DOI: 10.1016\/j.annonc.2020.02.011<\/div>\n
\u2461 \u8840\u6db2\u4e2dRNA\u53d1\u73b0\u53ef\u4f5c\u4e3a\u963f\u5179\u6d77\u9ed8\u75c7\u7684\u751f\u7269\u6807\u8bb0<\/div>\n
\u8bba\u6587\u51fa\u5904>>>DOI: 10.1016\/j.cub.2020.02.084<\/div>\n
\u2462 \u5229\u7528\u8bf1\u5bfc\u7684\u591a\u80fd\u5e72\u7ec6\u80de\u91cd\u6784\u4e86\u4eba\u7c7b\u53d1\u80b2\u7684\u751f\u7269\u949f<\/div>\n
\u8bba\u6587\u51fa\u5904>>>DOI: 10.1038\/s41586-020-2144-9<\/div>\n
\u2463 \u6d77\u6d0b\u5fae\u751f\u7269\u7814\u7a76\u7684200\u79cd\u6280\u672f\u5de5\u5177\u5305\u53d1\u5e03<\/div>\n
\u8bba\u6587\u51fa\u5904>>>DOI: 10.1038\/s41592-020-0796-x<\/div>\n
\u2464 \u53d1\u73b0\u6700\u65b0\u8010\u836f\u57fa\u56e0\uff0c\u62b5\u6297\u6700\u65b0\u6c28\u57fa\u7cd6\u82f7\u7c7b\u6297\u751f\u7d20<\/div>\n
\u8bba\u6587\u51fa\u5904>>>DOI: 10.1186\/s40168-020-00814-z<\/div>\n
\u2465\u00a0\u5728\u5bab\u5185\u57fa\u56e0\u6821\u6b63\u8033\u804b\u9057\u4f20\u75c5\uff08Usher\u7efc\u5408\u75c7\uff09<\/div>\n
\u8bba\u6587\u51fa\u5904>>>DOI:\u00a010.1093\/nar\/gkaa194<\/div>\n
\u00a0<\/div>\n
\u5e94\u7528<\/div>\n
\u91d1\u573b\u777f\u751f\u7269\u00a0| \u4e0eIllumina\u5408\u4f5c\u7684\u6d4b\u5e8f\u4eea\u83b7\u6279\u4e0a\u5e02<\/div>\n
4\u670810\u65e5\uff0c\u56fd\u5bb6\u836f\u76d1\u5c40\u6b63\u5f0f\u5ba1\u6279\u91d1\u573b\u777f\u751f\u7269\u548cIllumina\u5408\u4f5c\u5f00\u53d1\u7684\u684c\u9762\u5f0f\u9ad8\u901a\u91cf\u6d4b\u5e8f\u4eea\u201cKM MiniSeqDx-CN\u57fa\u56e0\u6d4b\u5e8f\u4eea\u201d\u4e0a\u5e02\u3002\uff08\u56fd\u5bb6\u836f\u76d1\u5c40\uff09<\/div>\n
\u539f\u6587\u89c1>>><\/div>\n
http:\/\/www.nmpa.gov.cn\/WS04\/CL2470\/376391.html<\/div>\n
\u3010\u7f16\u8005\u6309\u3011\u91d1\u573b\u777f\u751f\u7269\uff0c\u5bf9\u4e8e\u90e8\u5206\u8bfb\u8005\u53ef\u80fd\u6bd4\u8f83\u964c\u751f\u3002\u51e0\u4e4e\u662f3\u5e74\u524d\u540c\u4e00\u5468\uff084\u670815\u65e5\uff09\uff0c\u5e7f\u5dde\u91d1\u573b\u777f\u751f\u7269\u79d1\u6280\u6709\u9650\u8d23\u4efb\u516c\u53f8\u5ba3\u5e03\u6b63\u5f0f\u5f00\u4e1a\uff0c\u8fd9\u662f\u91d1\u57df\u68c0\u9a8c\u201c\u68c0\u9a8c+\u201d\u53d1\u5c55\u6218\u7565\u843d\u5730\u7684\u5173\u952e\u4e00\u6b65\uff0c\u610f\u5473\u7740\u6b63\u5f0f\u8fdb\u519bIVD\u9886\u57df\u3002<\/div>\n
1\u5e74\u534a\u540e\uff082018\u5e748\u670831\u65e5\uff09\uff0c\u91d1\u57df\u533b\u5b66\uff08SH.603882\uff09\u53d1\u5e03\u516c\u544a\u79f0\u62df\u5411\u5e7f\u5dde\u4f73\u9274\u751f\u7269\u6280\u672f\u6709\u9650\u516c\u53f8\u6574\u4f53\u51fa\u552e\u91d1\u573b\u777f\u751f\u7269\u7684100%\u80a1\u6743\uff0c\u4ea4\u6613\u91d1\u989d\u4e3a2900\u4e07\u5143\u4eba\u6c11\u5e01\u3002\u636e\u5206\u6790\uff0c\u5e7f\u5dde\u4f73\u9274\u751f\u7269\u6280\u672f\u6709\u9650\u516c\u53f8\u7684\u5b9e\u9645\u53d7\u76ca\u4eba\u4e3a\u91d1\u57df\u533b\u5b66\u8463\u4e8b\u957f\u517c\u9996\u5e2d\u6267\u884c\u5b98\u6881\u8000\u94ed\u548c\u6295\u8d44\u603b\u76d1\u738b\u667a\u98de\u5148\u751f\u3002<\/div>\n
\u00a0<\/div>\n
Keytruda | \u57fa\u4e8eTMB\u7684\u201c\u6cdb\u764c\u79cd\u201d\u6cbb\u7597\u7533\u8bf7\u83b7FDA\u4f18\u5148\u5ba1\u8bc4<\/div>\n
4\u67088\u65e5\uff0c\u9ed8\u6c99\u4e1c\uff08MSD\uff09\u5ba3\u5e03\uff0cFDA\u4f18\u5148\u5ba1\u8bc4\u5176\u4e3a\u91cd\u78c5PD-1\u6291\u5236\u5242Keytruda\u9012\u4ea4\u7684\u7b2c\u4e8c\u9879\u201c\u4e0d\u9650\u764c\u79cd\u201d\u8865\u5145\u751f\u7269\u5236\u54c1\u8bb8\u53ef\u7533\u8bf7\uff08sBLA\uff09\u3002Keytruda\u53ef\u7528\u4e8e\u6cbb\u7597\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\u9ad8\uff08TMB-H\uff09\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u7ecf\u6cbb\u5b9e\u4f53\u7624\u60a3\u8005\u3002\uff08\u836f\u660e\u5eb7\u5fb7\uff09<\/div>\n
\u6df1\u5ea6\u5206\u6790\u70b9\u51fb\u00a0>>><\/div>\n
\u6df1\u5ea6\u89e3\u8bfbKeytruda\u201c\u4e0d\u9650\u764c\u79cd\u201d\u7533\u8bf7\u83b7FDA\u4f18\u5148\u5ba1\u8bc4<\/a>\uff08\u836f\u660e\u5eb7\u5fb7\uff09<\/div>\n\n
\n
\"RmFicvQBAkgDNlkv85Nh4cc3dwJPiblBKjINpJ26v00R7snn45giaEQG8cssPpoyU1PYuWX46qIMWliaVXXV3oQEvw\"\/<\/figure><\/div>\n\n
\u4ea7\u4e1a<\/div>\n
\u793c\u6765&Sitryx | \u7b7e\u7f725\u5e74$8.8\u4ebf\u65b0\u51a0\u5f00\u53d1\u534f\u8bae<\/div>\n
\u7f8e\u56fd\u65f6\u95f43\u670831\u65e5\uff0c\u793c\u6765\u516c\u53f8\u4e0eSitryx\u7b7e\u7f72\u4e3a\u671f5\u5e74\u76848.8\u4ebf\u7f8e\u5143\u5f00\u53d1\u534f\u8bae\uff0c\u5171\u540c\u5f00\u53d14\u79cd\u7531Sitryx\u53d1\u73b0\u7684\u7528\u4e8e\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u4e34\u5e8a\u524d\u5316\u5408\u7269\u3002\u636e\u4ea4\u6613\u6761\u6b3e\uff0c\u793c\u6765\u5c06\u5411Sitryx\u9884\u4ed85000\u4e07\u7f8e\u5143\u548c1000\u4e07\u7f8e\u5143\u7684\u80a1\u6743\u6295\u8d44\u3002\uff08BioSpace\uff09<\/div>\n
\u539f\u6587\u89c1 >>><\/div>\n
https:\/\/www.biospace.com\/article\/lilly-and-sitryx-ink-partnership-to-develop-4-autoimmune-drugs\/<\/div>\n
\u00a0<\/div>\n
Myriad Genetics | \u6388\u6743\u6570\u95ee\u751f\u7269\u4ee3\u7406\u4e73\u817a\u764c\u68c0\u6d4b\u4ea7\u54c1<\/div>\n
\u8fd1\u65e5\uff0c\u6570\u95ee\u751f\u7269\u4e0e\u56fd\u9645\u77e5\u540d\u57fa\u56e0\u8bca\u65ad\u516c\u53f8Myriad Genetics\uff08\u9ea6\u5229\u4e9a\u5fb7\u9057\u4f20\u5b66\u516c\u53f8\uff09\u8fbe\u6210\u5173\u4e8e\u7b2c\u4e8c\u4ee3\u4e73\u817a\u764c\u591a\u57fa\u56e0\u9884\u540e\u4ea7\u54c1EndoPredict\u7684\u72ec\u5bb6\u5408\u4f5c\uff0c\u6570\u95ee\u751f\u7269\u88ab\u6388\u4e88\u5728\u4e2d\u56fd\u5927\u9646\u72ec\u5bb6\u68c0\u6d4b\u548c\u63a8\u5e7fEndoPredict\u7684\u6743\u5229\u3002\uff08\u836f\u667a\u65b0\u95fb\uff09<\/div>\n
\u00a0<\/div>\n
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4\u67089\u65e5\uff0c\u542f\u660e\u521b\u6295\u5ba3\u5e03\u5b8c\u6210\u7b2c\u4e03\u671f\u7f8e\u5143\u57fa\u91d1\u7684\u52df\u8d44\uff0c\u65b0\u57fa\u91d1\u7684\u89c4\u6a21\u4e3a11\u4ebf\u7f8e\u5143\uff0c\u4e13\u6ce8\u4e8e\u533b\u7597\u5065\u5eb7\u548cTMT\u4e24\u4e2a\u9886\u57df\u7684\u65e9\u671f\u6295\u8d44\u3002\uff08\u542f\u660e\u521b\u6295\uff09<\/div>\n
4\u67088\u65e5\uff0c\u534e\u76d6\u8d44\u672c\u533b\u7597\u4e09\u671f\u57fa\u91d1\u5ba3\u5e03\u6574\u4f53\u5173\u95ed\uff0c\u5168\u90e8LP\u5df2\u5b8c\u6210\u9996\u6b21\u51fa\u8d44\uff0c\u52df\u8d44\u91d1\u989d\u8fbe30.66\u4ebf\u5143\u4eba\u6c11\u5e01\u3002\uff08\u6295\u8d44\u754c\uff09<\/div>\n
\u00a0<\/div>\n
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4\u67084\u65e5\uff0c\u56fd\u5bb6\u536b\u5065\u59d4\u4e34\u5e8a\u68c0\u9a8c\u4e2d\u5fc3\u53d1\u5e03\u300a\u5173\u4e8e\u514d\u8d39\u63d0\u4f9b\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u6838\u9178\u68c0\u6d4b\u8d28\u63a7\u54c1\uff08\u539f\u6599\uff09\u7684\u901a\u77e5\u300b\uff0c\u7528\u4e8e\u5b9e\u9a8c\u5ba4\u5ba4\u5185\u8d28\u91cf\u63a7\u5236\u3001\u6027\u80fd\u9a8c\u8bc1\u6216\u8bd5\u5242\u65b9\u6cd5\u5efa\u7acb\u7684\u6027\u80fd\u786e\u8ba4\u7b49\u3002\uff08NCCLmys\uff09<\/div>\n
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\u00a0<\/div>\n
Wellcome\u00a0| \u8ba1\u5212\u52df\u8d4480\u4ebf\u7f8e\u5143\u7528\u4e8e\u65b0\u51a0\u6218\u75ab<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
\u00a0\u5173\u4e8e\u57fa\u56e0\u6167\u00a0<\/div>\n
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\u2606\u00a0\u53d7\u9080\u4e3a\u534e\u897f\u533b\u9662<\/a>\u3001Illumina<\/a>\u3001\u534e\u5927<\/a>\u3001\u4e0a\u6d77\u4ea4\u5927<\/a>\u7b49\u5927\u4f1a\u4f5c\u62a5\u544a<\/div>\n
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\u00a0<\/div>\n
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