{"id":9113,"date":"2020-04-15T16:00:20","date_gmt":"2020-04-15T08:00:20","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&#038;mid=100013130&#038;idx=1&#038;sn=34e6ff8da99e24cbf310b986aeabff51&#038;chksm=6b7146fd5c06cfeb92c230e22b31c8fed25383b0bfa3a0c3a857e56409e6b426a0928dde9e30#rd"},"modified":"2026-04-02T10:06:47","modified_gmt":"2026-04-02T02:06:47","slug":"555052-2","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2020\/04\/15\/555052-2\/","title":{"rendered":"\u5fc5\u8bfb\u5e72\u8d27\uff01\u80ba\u764c\u540d\u5bb6\u738b\u6d01\u89e3\u6790\u201d\u80ba\u764c\u57fa\u56e0\u68c0\u6d4b\u4e0e\u7cbe\u51c6\u6cbb\u7597\u201c\u5b9e\u5f55"},"content":{"rendered":"<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCNyD7F9HPgIG1a3S7k00rEjudtOHsc9ibuqmInQ2y76b09WJMYRQlJLGlgcMXgAbF0t4pURhPvH8w.jpeg\" 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Mutational 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Tumor Cells\uff0cCTC)\uff0c\u662f\u901a\u8fc7\u7279\u5b9a\u7684\u65b9\u6cd5\u628a\u8840\u6db2\u4e2d\u7684\u80bf\u7624\u7ec6\u80de\u5206\u9009\u51fa\u6765\uff0c\u518d\u505a\u8fdb\u4e00\u6b65\u7684\u5206\u6790\u3002CTC\u76ee\u524d\u56e0\u4e3a\u5206\u9009\u6280\u672f\u7684\u5c40\u9650\uff0c\u5728\u4e34\u5e8a\u5e94\u7528\u4e0a\u8fd8\u6ca1\u6709\u7279\u522b\u597d\u7684\u8fdb\u5c55\u3002\u4ee5\u80ba\u817a\u764c\u4e3a\u4f8b\uff0c\u505a\u4e00\u6b21\u6700\u591a\u62ff\u5230\u4e09\u56db\u4e2a\u7624\u7ec6\u80de\uff0c\u56e0\u4e3a\u80bf\u7624\u5f02\u8d28\u6027\u7684\u95ee\u9898\uff0c\u4e5f\u5f88\u96be\u53cd\u6620\u6574\u4e2a\u80bf\u7624\u7ec4\u7ec7\u7684\u60c5\u51b5\u3002\u6240\u4ee5\u548cctDNA\u76f8\u6bd4\uff0cCTC\u9762\u4e34\u7684\u6311\u6218\u66f4\u52a0\u4e25\u5cfb\uff0c\u5e94\u7528\u53d7\u5230\u9650\u5236\u3002<\/div>\n<div>\u7b2c\u4e09\u79cd\u6db2\u4f53\u6d3b\u68c0\u662f\u68c0\u6d4b\u4e00\u79cd\u53eb\u5916\u6ccc\u4f53\u7684\u65b9\u6cd5\uff0c\u5b83\u53ef\u4ee5\u7528\u6765\u505a\u57fa\u56e0\u5206\u6790\u751a\u81f3PD-L1\u8868\u8fbe\u7b49\uff0c\u76ee\u524d\u8fd8\u5728\u7814\u7a76\u9636\u6bb5\uff0c\u4e34\u5e8a\u5e94\u7528\u8fd8\u9700\u8981\u66f4\u591a\u7814\u7a76\u3002<\/div>\n<div>\u00a0<\/div>\n<div>14<\/div>\n<div>\u5f88\u591a\u80ba\u764c\u60a3\u8005\u975e\u5e38\u62c5\u5fc3\u590d\u53d1\u3002\u73b0\u5728\u6709\u7814\u7a76\uff0c\u6bcf\u8fc7\u51e0\u4e2a\u6708\u7528\u6db2\u6001\u6d3b\u68c0\u68c0\u6d4b\u4e00\u6b21\uff0c\u662f\u4e0d\u662f\u6709\u53ef\u80fd\u6bd4\u5f71\u50cf\u68c0\u6d4b\u66f4\u65e9\u7684\u53d1\u73b0\u590d\u53d1\u7076\uff1f<\/div>\n<div>\u3010\u738b\u6559\u6388\u3011\u73b0\u5728\u7684\u60a3\u8005\uff0c\u603b\u4f53\u6bd4\u8d7710\u5e74\u524d\u5bf9\u75be\u75c5\u7684\u4e86\u89e3\u3001\u8ba4\u8bc6\u548c\u5173\u6ce8\u5ea6\u4e0a\u5df2\u7ecf\u5927\u5927\u7684\u8fdb\u6b65\u3002\u7ecf\u5e38\u4e34\u5e8a\u4e0a\u6709\u75c5\u4eba\u95ee\u6211\uff0c\u201c\u6211\u76ee\u524d\u8fd8\u6ca1\u6709\u8fdb\u5c55\uff0c\u4f46\u662f\u6211\u9700\u4e0d\u9700\u8981\u53bb\u505a\u6db2\u4f53\u6d3b\u68c0\u201d\u3002\u8fd9\u4e9b\u60f3\u6cd5\u53ef\u80fd\u5c31\u662f\u6e90\u81ea\u83e0\u841d\u8001\u5e08\u548c\u5f88\u591a\u4e13\u5bb6\u4eec\u7684\u79d1\u666e\u3002\u73b0\u5728\u56fd\u5185\u5916\u6709\u8fd9\u6837\u7684\u7814\u7a76\uff0c\u8bb2\u7684\u662f\u672a\u96e8\u7ef8\u7f2a\u800c\u4e0d\u662f\u4ea1\u7f8a\u8865\u7262\u3002<\/div>\n<div>\u73b0\u5728\u6211\u4eec\u6709\u8fd9\u4e48\u591a\u7684\u6cbb\u7597\u65b9\u6cd5\uff0cEGFR\u9776\u5411\u836f\u5c31\u6709\u4e09\u4ee3\uff0c\u5f88\u5feb\u4f1a\u6709\u56db\u4ee3\u3002\u90a3\u6db2\u4f53\u6d3b\u68c0\u7ed3\u5408\u4e8c\u4ee3\u6d4b\u5e8f\uff0c\u672a\u6765\u8fd8\u6709\u5355\u5206\u5b50\u6d4b\u5e8f\uff0c\u662f\u5426\u53ef\u80fd\u63d0\u524d\u9884\u77e5\u8010\u836f\u7684\u51fa\u73b0\uff0c\u4e0d\u7b49\u5b83\u4e34\u5e8a\u8fdb\u5c55\u3001\u75c7\u72b6\u52a0\u91cd\uff0c\u800c\u662f\u63d0\u524d\u505a\u5e72\u9884\uff1f\u8fd9\u6837\u662f\u4e0d\u662f\u80fd\u5f97\u5230\u66f4\u957f\u7684\u751f\u5b58\u65f6\u95f4\uff1f<\/div>\n<div>\u4ece\u7406\u8bba\u4e0a\u662f\u8fd9\u6837\uff0c\u56fd\u9645\u56fd\u5185\u7684\u4e13\u5bb6\u4e5f\u5728\u5f00\u5c55\u4e00\u4e9b\u4e0d\u540c\u7684\u5e72\u9884\u65f6\u95f4\u8282\u70b9\u7684\u4e34\u5e8a\u7814\u7a76\u3002\u4f46\u662f\u8fc4\u4eca\u4e3a\u6b62\u6ca1\u6709\u4e00\u4e2a\u5f88\u597d\u7684\u7ed3\u679c\u62a5\u544a\u3002\u6240\u4ee5\u6211\u4eec\u90fd\u5728\u671f\u5f85\u3002<\/div>\n<div>\u5982\u679c\u6709\u75c5\u4eba\u6709\u9700\u6c42\uff0c\u7ecf\u6d4e\u6761\u4ef6\u53ef\u4ee5\u627f\u62c5\u7684\u60c5\u51b5\u4e0b\uff0c\u53ef\u4e0d\u53ef\u4ee5\u63d0\u524d\u53bb\u8bd5\u8bd5\uff1f\u6211\u89c9\u5f97\u662f\u53ef\u4ee5\u7684\uff0c\u6700\u597d\u53ef\u4ee5\u7eb3\u5165\u5230\u7814\u7a76\u91cc\u53bb\u3002\u4f46\u662f\u73b0\u5728\u5c1a\u672a\u4f5c\u4e3a\u5e38\u89c4\u63a8\u8350\uff0c\u56e0\u4e3a\u6bd5\u7adf\u6ca1\u6709\u6570\u636e\u3002<\/div>\n<div><iframe src=\"https:\/\/v.qq.com\/txp\/iframe\/player.html?vid=wxv_1295954025682321410\" frameborder=\"0\" 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\u3002\u533b\u751f\u503e\u5411\u662f\u80bf\u7624\u4f46\u662f\u4e0d\u80fd\u6392\u9664\u662f\u522b\u7684\u708e\u75c7\u6216\u8005\u80ba\u7ed3\u6838\uff0c\u8bf7\u95ee\u73b0\u5728\u9760\u57fa\u56e0\u68c0\u6d4b\u6216\u8005\u6db2\u4f53\u6d3b\u68c0\u662f\u5426\u53ef\u4ee5\u533a\u5206\u4e0d\u540c\u7684\u9634\u5f71\uff1f<\/div>\n<div>\u3010\u738b\u6559\u6388\u3011\u521a\u521a\u8c08\u523080\u5c81\u60a3\u8005\uff0c\u75f0\u4e2d\u6709\u8840\uff0c\u9996\u5148\u91cd\u8981\u7684\u662f\u505a\u75f0\u6db2\u7684\u7ec6\u80de\u5b66\u68c0\u67e5\uff0c\u6700\u597d\u662f\u628a\u5e26\u8840\u7684\u75f0\u6db2\u6536\u96c6\u8d77\u6765\u53bb\u505a\u68c0\u6d4b\u3002\u5982\u679c80\u5c81\u8001\u4eba\uff0c\u5468\u56f4\u578b\u80ba\u764c\uff0c\u80ba\u57fa\u7840\u60c5\u51b5\u5dee\uff0c\u5982\u4f34\u6709\u4e25\u91cd\u7684\u80ba\u6c14\u80bf\u3001\u80ba\u5927\u6ce1\uff0c\u90a3\u80ba\u7a7f\u523a\u6d3b\u68c0\u6709\u98ce\u9669\uff0c\u5c31\u53ef\u505a\u5916\u5468\u8840\u57fa\u56e0\u68c0\u6d4b\u3002\u82e5\u57fa\u56e0\u7a81\u53d8\u9633\u6027\uff0c\u5bf9\u6cbb\u7597\u5c31\u4f1a\u6709\u5e2e\u52a9\u3002\u5f53\u7136\u8fd8\u8981\u505a\u4e00\u4e2a\u5168\u9762\u7684\u5206\u671f\u68c0\u67e5\uff0c\u770b\u770b\u5176\u4ed6\u90e8\u4f4d\uff0c\u5982\u809d\u3001\u8111\u3001\u9aa8\u7b49\u810f\u5668\u662f\u5426\u6709\u8f6c\u79fb\u3002<\/div>\n<div>\u00a0<\/div>\n<div>19<\/div>\n<div>\u6709\u4eba\u590d\u67e5\u65f6\u5019\u53d1\u73b0\u80bf\u7624\u8fdb\u5c55\u4e86\u3002\u57fa\u56e0\u68c0\u6d4b\u4ee5\u524d\u662fEGFR\u57fa\u56e019\u53f7\u5916\u663e\u5b50\u7f3a\u5931\uff0c\u518d\u6b21\u68c0\u6d4b\u6ca1\u6709\u53d1\u73b0\u6709\u65b0\u7684\u7a81\u53d8\u3002\u8fd9\u65f6\u5e94\u8be5\u76f4\u63a5\u6362\u4e09\u4ee3\uff0c\u8fd8\u662f\u5e94\u8be5\u52a0\u4e0a\u522b\u7684\u7597\u6cd5\u505a\u8054\u5408\u6cbb\u7597\uff1f<\/div>\n<div>\u3010\u738b\u6559\u6388\u3011\u6211\u4e0d\u77e5\u9053\u4ed6\u505a\u7684\u57fa\u56e0\u68c0\u6d4b\u5957\u9910\u6709\u591a\u5927\uff0c\u6709\u6ca1\u6709\u6ca1\u770b\u5230T790M\u6216\u8005cMET\u7b49\u8010\u836f\u57fa\u56e0\u7684\u6539\u53d8\u3002\u5982\u679c\u68c0\u6d4b\u5957\u9910\u8db3\u591f\u5927\uff0c\u4f46\u6ca1\u6709\u51fa\u73b0\u660e\u786e\u8010\u836f\u7a81\u53d8\u7684\u8bdd\uff0c\u53ef\u4ee5\u8003\u8651\u6362\u4e8c\u4ee3\u9776\u5411\u836f\uff0c\u56e0\u4e3a\u4e8c\u4ee3\u836f\u7269\u662f\u66f4\u5e7f\u8c31\u7684\u4e00\u4e2a\u6291\u5236\u5242\u3002\u5728\u65e2\u5f80\u7684\u7814\u7a76\u91cc\u9762\uff0c\u5982\u679c\u6ca1\u6709\u68c0\u6d4b\u5230T790M\u8010\u836f\u7a81\u53d8\u7684\u65f6\u5019\uff0c\u5bf9\u8fd9\u79cd\u75c5\u4eba\u7528\u4e8c\u4ee3\u7684\u836f\u7269\uff0c \u5176\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u7684\u65f6\u95f4\u5927\u6982\u662f\u4e09\u4e2a\u6708\u5de6\u53f3\u3002\u6240\u4ee5\u81f3\u5c11\u8fd8\u6709\u4e2d\u4f4d\u4e09\u4e2a\u6708\u7684\u65f6\u95f4\u53bb\u5598\u53e3\u6c14\uff0c\u518d\u53bb\u505a\u5176\u4ed6\u7684\u68c0\u67e5\u3002<\/div>\n<div>\u81f3\u4e8e\u8981\u4e0d\u8981\u6362\u4e09\u4ee3\u836f\u7269\uff0c\u53d6\u51b3\u4e8e\u662f\u54ea\u4e2a\u90e8\u4f4d\u7684\u8fdb\u5c55\u3002\u5982\u679c\u9885\u5185\u8fdb\u5c55\u4e86\uff0c\u56e0\u4e3a\u4e09\u4ee3\u836f\u7269\u5165\u8111\u76f8\u5bf9\u597d\u4e00\u70b9\uff0c\u5373\u4f7f\u6ca1\u6709\u68c0\u6d4b\u5230T790M\u8010\u836f\u7a81\u53d8\uff0c\u6362\u4e09\u4ee3\u836f\u7269\u662f\u53ef\u4ee5\u7684\u3002\u5982\u679c\u51fa\u73b0\u809d\u810f\u6216\u8005\u9aa8\u591a\u810f\u5668\u8f6c\u79fb\uff0c\u7624\u8d1f\u8377\u5927\uff0c\u540c\u65f6\u8eab\u4f53\u72b6\u6001\u597d\uff0c\u8fd8\u53ef\u4ee5\u8054\u5408\u5316\u7597\u3002\u56e0\u6b64\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u4e00\u5b9a\u8981\u4e2a\u6027\u5316\u5730\u8bca\u6cbb\u3002<\/div>\n<div>\u00a0<\/div>\n<div>20<\/div>\n<div>\u4f53\u5185\u53d1\u73b0\u591a\u53d1\u7ed3\u8282\uff0c\u53d6\u4e86\u5176\u4e2d\u4e00\u4e2a\uff0c\u53d1\u73b0\u662f1A\u671f\uff0c\u57fa\u56e0\u68c0\u6d4b\u53d1\u73b0 EGFR\u7a81\u53d8\u3002\u662f\u4e0d\u662f\u9ed8\u8ba4\u5176\u4ed6\u7684\u7ed3\u8282\u4e5f\u662f\u8fd9\u79cd\u7a81\u53d8\u7684\uff1f\u8fd8\u662f\u8bf4\u5b83\u4eec\u90fd\u662f\u72ec\u7acb\u7684\uff1f<\/div>\n<div>\u3010\u738b\u6559\u6388\u3011\u4e0d\u4e00\u5b9a\u3002\u73b0\u5728\u53d1\u73b0\u591a\u53d1\u7684\u5c0f\u7ed3\u8282\u8d8a\u6765\u8d8a\u591a\u3002\u6709\u62a5\u9053\u8fc7\u4e00\u4f4d\u60a3\u8005\u4e24\u80ba\u7684\u7ed3\u8282\uff0c\u5206\u671f\u624b\u672f\uff0c\u5206\u522b\u53d6\u51fa\u51e0\u4e2a\u7ed3\u8282\uff0c\u6bcf\u4e2a\u7ed3\u8282\u57fa\u56e0\u68c0\u6d4b\u4e0d\u5c3d\u76f8\u540c\u3002\u56e0\u4e3a\u591a\u53d1\u7ed3\u8282\u53ef\u80fd\u662f\u591a\u4e2d\u5fc3\u8d77\u6e90\u7684\u80bf\u7624\uff0c\u800c\u4e0d\u662f\u8f6c\u79fb\uff0c\u57fa\u56e0\u8868\u73b0\u5b8c\u5168\u53ef\u4ee5\u4e0d\u4e00\u6837\u3002\u8fd9\u53ef\u4ee5\u5e2e\u52a9\u6211\u4eec\u9274\u522b\u764c\u6027\u7ed3\u8282\u662f\u8f6c\u79fb\u8fd8\u662f\u591a\u4e2d\u5fc3\u8d77\u6e90\u3002<\/div>\n<div>\u3010\u83e0\u841d\u3011\u4ece\u67d0\u4e2a\u89d2\u5ea6\u4f60\u5176\u5b9e\u5e0c\u671b\u5b83\u4eec\u662f\u4e0d\u4e00\u6837\u7684\uff0c\u5982\u679c\u662f\u4e00\u6837\u7684\u8bdd\uff0c\u8bf4\u660e\u8f6c\u79fb\u7684\u6982\u7387\u4f1a\u5927\u3002<\/div>\n<div>\u3010\u738b\u6559\u6388\u3011\u5bf9\u7684\u3002\u8fd8\u8981\u7ed3\u5408\u5f71\u50cf\u3002<\/div>\n<div>\u00a0<\/div>\n<div>21<\/div>\n<div>EGFR 18\u548c20\u53f7\u5916\u663e\u5b50\u7a81\u53d8\u6709\u6ca1\u6709\u4ec0\u4e48\u597d\u7684\u836f\u7269\u6216\u8005\u503c\u5f97\u671f\u5f85\u7684\u836f\u7269\uff1f<\/div>\n<div>\u3010\u738b\u6559\u6388\u3011\u8fd9\u4e24\u4e2a\u7a81\u53d8\u4f4d\u70b9\u4e5f\u6709\u4e00\u4e9b\u836f\u7269\uff0c\u5c24\u5176\u67d0\u4e9b18\u53f7\u5916\u663e\u5b50\u7a81\u53d8\uff0c\u4f7f\u7528\u4e8c\u4ee3\u9776\u5411\u836f\uff0c\u4e5f\u5c31\u662f\u6cdbEGFR\u6291\u5236\u5242\uff0c\u4e2d\u4f4d\u65e0\u8fdb\u5c55\u751f\u5b58\u671f\u65f6\u95f47-8\u4e2a\u6708\u5de6\u53f3\u3002\u6bd4\u8f83\u96be\u6cbb\u7684\u5c31\u662fEGFR 20\u63d2\u5165\u7a81\u53d8\uff0c\u4e00\u4e8c\u4e09\u4ee3\u836f\u7269\u6548\u679c\u90fd\u4e0d\u592a\u597d\u3002\u503c\u5f97\u5e86\u5e78\u7684\u662f\uff0c\u6709\u50cf\u6ce2\u9f50\u66ff\u5c3c(Poziotinib)\u6216\u4e00\u4e9b\u7c7b\u4f3c\u836f\u7269\u7684\u4e34\u5e8a\u7814\u7a76\u6b63\u5728\u56fd\u5185\u5916\u5f00\u5c55\uff0c\u53ef\u4ee5\u53c2\u52a0\u3002<\/div>\n<div>\u8fd8\u6709\u4e00\u4e2a\u5728\u4e73\u817a\u764c\u91cc\u9488\u5bf9HER2\u7684\u836f\u7269\u53eb\u5421\u54af\u66ff\u5c3c\uff0c\u53ef\u80fd\u5bf9\u80ba\u764c20\u53f7\u5916\u663e\u5b50\u63d2\u5165\u7a81\u53d8\u4e5f\u662f\u6709\u6548\u7684\u3002\u8fd9\u4e24\u5e74\u548c\u672a\u6765\u7684\u9776\u5411\u6cbb\u7597\u7814\u7a76\u91cd\u70b9\u4e5f\u5c06\u805a\u7126\u4e8e\u8fd9\u4e9b\u96be\u6cbb\u7684\u3001\u6311\u6218\u6027\u5927\u7684\u9776\u70b9\u65b9\u9762\uff0c\u5305\u62ec\u6211\u4eec\u81ea\u5df1\u4e2d\u5fc3\u4e5f\u6709\u4e00\u4e2a\u9488\u5bf920\u53f7\u63d2\u5165\u7a81\u53d8\u6548\u679c\u6bd4\u8f83\u597d\u7684\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/div>\n<div>\u00a0<\/div>\n<div>22<\/div>\n<div>EGFR\u3001ALK\u3001ROS1\u8fd9\u4e09\u4e2a\u7a81\u53d8\uff0c\u5f88\u591a\u4eba\u90fd\u633a\u719f\u6089\u7684\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u8fd8\u6709\u54ea\u51e0\u4e2a\u57fa\u56e0\u7a81\u53d8\u662f\u660e\u786e\u6709\u9776\u5411\u836f\u80fd\u6cbb\u7684\uff1f<\/div>\n<div>\u3010\u738b\u6559\u6388\u301170%-80%\u80ba\u817a\u764c\u9a71\u52a8\u57fa\u56e0\u8c31\u5df2\u7ecf\u5f88\u660e\u767d\u3002\u5e76\u4e14\u76f8\u5e94\u7684\u836f\u7269\u4e5f\u662f\u8d8a\u6765\u8d8a\u591a\uff0c\u6240\u4ee5\u5927\u5bb6\u4e00\u5b9a\u8981\u6709\u4fe1\u5fc3\u3002\u9cde\u764c\u548c\u5c0f\u7ec6\u80de\u80ba\u764c\u6211\u89c9\u5f97\u8c03\u6574\u7814\u7a76\u601d\u8def\u8d70\u81f3\u6b63\u786e\u9053\u7406\u540e\uff0c\u4e5f\u662f\u6307\u65e5\u53ef\u5f85\uff1b\u5e94\u5728\u514d\u75ab\u6cbb\u7597\u4e0a\u505a\u66f4\u591a\u66f4\u6df1\u5165\u7684\u63a2\u7d22\uff0c\u5305\u62ec\u9884\u6d4b\u6807\u5fd7\u3001\u8010\u836f\u7b49\u3002\u8fd8\u6709\u6297\u4f53\u5076\u8054\u836f\u7269\u4ea6\u503c\u5f97\u671f\u5f85\u3002<\/div>\n<div>\u00a0<\/div>\n<div>cMET \u7a81\u53d8<\/div>\n<div>\u53ef\u4ee5\u9009\u62e9\u514b\u5511\u66ff\u5c3c\u6216\u4e00\u4e9b\u65b0\u7684cMET\u6291\u5236\u5242\u3002<\/div>\n<div>RET\u7a81\u53d8<\/div>\n<div>\u6709\u975e\u9009\u62e9\u6027\u7684RET\u6291\u5236\u5242\uff0c\u6bd4\u5982\u5361\u535a\u66ff\u5c3c\uff1b\u9009\u62e9\u6027\u7684RET\u6291\u5236\u5242\u5c31\u662f LOXO-292\u7b49\uff0c\u8fd9\u4e9b\u836f\u7269\u76ee\u524d\u56fd\u5185\u5916\u5747\u6709\u505a\u7814\u7a76\u3002<\/div>\n<div>\u80ba\u764c\u91cc\u7684HER2\u7a81\u53d8<\/div>\n<div>\u53ef\u4ee5\u9009\u62e9\u4e8c\u4ee3\u836f\u7269\u963f\u6cd5\u66ff\u5c3c\u6216\u8005\u662f\u5421\u54af\u66ff\u5c3c\u7b49\uff0c\u6709\u65f6\u5019\u897f\u59a5\u6614\u5355\u6297\u5355\u514b\u9686\u6297\u4f53\u8054\u5408\u5316\u7597\u4ea6\u53ef\u5c1d\u8bd5\u3002\u3002\u8fd8\u6709\u5c31\u662f\u9ed1\u8272\u7d20\u7624\u91cc\u6bd4\u8f83\u5e38\u89c1\u7684BRAF\u7a81\u53d8\uff0c\u5728\u80ba\u764c\u4ea6\u6709BRAF V600E\u7684\u53d8\u5f02\uff0c\u5bf9\u8fd9\u4e2a\u7a81\u53d8\u4f4d\u70b9\uff0c\u53ef\u7ed9\u4e88\u66f2\u7f8e\u66ff\u5c3c\u8054\u5408\u7ef4\u7f57\u975e\u5c3c\u6cbb\u7597\u3002\u836f\u7269\u3002<\/div>\n<div>KRAS \u7a81\u53d8<\/div>\n<div>\u8fd9\u662f\u5168\u4e16\u754c\u80bf\u7624\u4eba\u5fc3\u4e2d\u7684\u75db\u3002KRAS\u7a81\u53d8\u7684\u53d1\u73b0\u6bd4EGFR\u8fd8\u8981\u65e9\uff0c\u56db\u5341\u591a\u5e74\u4e00\u76f4\u6ca1\u6709\u6709\u6548\u836f\u7269\u3002\u4f46\u662f\u6700\u8fd1\u6709\u4e00\u4e9b\u6d88\u606f\u3002\u6bd4\u5982AMG510\u6216\u66f2\u7f8e\u66ff\u5c3c\u52a0\u4e0a\u591a\u897f\u4ed6\u8d5b\uff0c\u5bf9\u4e8eKRAS 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jiyinhui_1\uff0c\u90ae\u7bb1 info@genonet.cn )\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u62d3\u5c55\u9605\u8bfb<\/div>\n<div>\u25b2\u00a0<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247496775&amp;idx=1&amp;sn=edcbf9aeb22ccb179651d4a669734a03&amp;chksm=eb7146f0dc06cfe63a4469cefa7ed4c48af25fc6eddbe229e6910a71df4f5fc82c1683e94b2d&amp;scene=21#wechat_redirect\">\u57fa\u56e0\u884c\u4e1a\u6700\u65b0\u8d44\u8baf\u2014\u2014\u57fa\u56e0\u7b80\u62a5GeneMail No 91\u671f<\/a><\/div>\n<div>\u25b2\u00a0<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247496763&amp;idx=1&amp;sn=c2cf83fc3c832df6abe2035fdff6c7ea&amp;chksm=eb71468cdc06cf9a51b8d50a5e757a6b7f87e1b2d60ecd2a31dd20fdff182787e5be8ca0e0b6&amp;scene=21#wechat_redirect\">\u524dFDA\u8d44\u6df1\u4e13\u5bb6\u51fa\u4efb\u764c\u75c7\u7cbe\u51c6\u533b\u7597\u516c\u53f8\u6cdb\u751f\u5b50\u9996\u5e2d\u533b\u7597\u5b98<\/a><\/div>\n<div>\u25b2\u00a0<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247496560&amp;idx=1&amp;sn=492086c4f0896685d6a492e24f96f42a&amp;chksm=eb7141c7dc06c8d1bcd4bb734dec7864bba7caefe37e2c4a3982ef611aa0c426af6f2f5e8da9&amp;scene=21#wechat_redirect\">\u300a2020\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b\u589e\u8ba2\u7535\u5b50\u7248\u53d1\u5e03<\/a>\u00a0<\/div>\n<div>\u25b2\u00a0<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247496351&amp;idx=1&amp;sn=d50d36d5214ba002667525cb884d6590&amp;chksm=eb714028dc06c93e5de4292889b3127f14b385c3fff3e8ded5c9788b23c6a59d23b1d0d01671&amp;scene=21#wechat_redirect\">\u57fa\u56e0\u6167\u53c2\u4e0e\u56fd\u53d1\u6539\u6700\u65b0\u300a\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b<\/a>\u7f16\u5199<\/div>\n<div>\u00a0<\/div>\n<div>\u00a0\u5173\u4e8e\u57fa\u56e0\u6167\u00a0<\/div>\n<div>\u57fa\u56e0\u6167\u662f\u4e00\u5bb6\u72ec\u7acb\u7684\u57fa\u56e0\u884c\u4e1a\u54a8\u8be2\u673a\u6784\u3002\u57fa\u4e8e10+\u5e74\u4ea7\u4e1a\u5b9e\u8df5\uff0c1000+\u4f01\u4e1a\u5e93YourMap\u00ae\uff0c\u6211\u4eec\u63d0\u4f9b\u57fa\u56e0\u4ea7\u4e1a\u54a8\u8be2\u3001\u8d44\u8baf\u548c\u54c1\u724c\u670d\u52a1\uff0c\u5e2e\u52a9\u5408\u4f5c\u4f19\u4f34\u6d1e\u5bdf\u5e02\u573a\uff0c\u670d\u52a1\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u521b\u65b0\u521b\u4e1a\u3002<\/div>\n<div>\u2606\u00a0<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247496351&amp;idx=1&amp;sn=d50d36d5214ba002667525cb884d6590&amp;chksm=eb714028dc06c93e5de4292889b3127f14b385c3fff3e8ded5c9788b23c6a59d23b1d0d01671&amp;scene=21#wechat_redirect\">\u56fd\u5bb6\u53d1\u6539\u59d4\u300a\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b\u7f16\u59d4<\/a><\/div>\n<div>\u2606\u00a0\u7ec4\u7ec7\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\uff08\u7b79\uff09\u53ca<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247485809&amp;idx=1&amp;sn=ed212d2f2640470ee7269e9959868dcc&amp;chksm=eb72bbc6dc0532d0fea4edea3a9b2aaf23affe391982bdf651b0322120844c1546119d1d475a&amp;scene=21#wechat_redirect\">\u7b2c\u4e00\u5c4a<\/a>\u548c<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247493932&amp;idx=1&amp;sn=7e68c7e9c7d5b5479e6e4aa540ca569f&amp;chksm=eb715b9bdc06d28d4944c5584d99a68977413620e4dfbb4716376a4b8a5ce7b6b1b1129b5d4f&amp;scene=21#wechat_redirect\">\u7b2c\u4e8c\u5c4a<\/a><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247493932&amp;idx=1&amp;sn=7e68c7e9c7d5b5479e6e4aa540ca569f&amp;chksm=eb715b9bdc06d28d4944c5584d99a68977413620e4dfbb4716376a4b8a5ce7b6b1b1129b5d4f&amp;scene=21&amp;token=775963598&amp;lang=zh_CN#wechat_redirect\">\u4f1a\u8bae<\/a><\/div>\n<div>\u2606\u00a0\u4e2d\u56fd\u9057\u4f20\u5b66\u4f1a\u751f\u7269\u4ea7\u4e1a\u4fc3\u8fdb\u59d4\u5458\u4f1a\u59d4\u5458<\/div>\n<div>\u2606\u00a0\u8fde\u7eed\u4e09\u5e74\u53d1\u5e03\u6743\u5a01\u7684\u5e74\u5ea6<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247496560&amp;idx=1&amp;sn=492086c4f0896685d6a492e24f96f42a&amp;chksm=eb7141c7dc06c8d1bcd4bb734dec7864bba7caefe37e2c4a3982ef611aa0c426af6f2f5e8da9&amp;scene=21#wechat_redirect\">\u57fa\u56e0\u884c\u4e1a\u62a5\u544a<\/a><\/div>\n<div>\u2606\u00a0\u53d1\u5e03\u9996\u4e2a\u57fa\u56e0\u884c\u4e1a\u4fe1\u606f\u5e73\u53f0<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247487212&amp;idx=1&amp;sn=eb777cac45525cc85b37a9bb65b907a6&amp;chksm=eb72bc5bdc05354d20954103276e0dd35481b5f535719f8fad3e4eeb4fe49a7b200cd2239990&amp;scene=21#wechat_redirect\">\u4f18\u8109\u901aYourMap<\/a><\/div>\n<div>\u2606\u00a0\u53c2\u4e0e<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247487811&amp;idx=1&amp;sn=54fe9c1cef11de022168ef5c55dc0efb&amp;chksm=eb72a3f4dc052ae21d2577929f563ff06c451d7f6872fa954270530468187cc5844ba5ade4d3&amp;scene=21#wechat_redirect\">\u57fa\u56e0\u68c0\u6d4b\u62a5\u544a\u89c4\u8303<\/a>\u3001<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247496540&amp;idx=1&amp;sn=23f504b79153aa504a6210075240d3bd&amp;chksm=eb7141ebdc06c8fd594371705ea519c453fc6d9824620bb801d8699461d116c5c79388db51fc&amp;scene=21#wechat_redirect\">\u57fa\u56e0\u68c0\u6d4b\u5168\u6d41\u7a0b<\/a>\u7b49\u5171\u8bc6\u548c<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247492716&amp;idx=2&amp;sn=42172a31609509cab04d3db2bb0d33a0&amp;chksm=eb7156dbdc06dfcd33b2eb613ec6aaee77893218c4531c1eda9d0cba5f855d767e430d76e7f5&amp;scene=21#wechat_redirect\">\u56e2\u4f53\u6807\u51c6<\/a><\/div>\n<div>\u2606\u00a0\u4e3b\u529e<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247488145&amp;idx=1&amp;sn=d62b3d6ead2512e2c448d9a9ee9ab61f&amp;chksm=eb72a026dc052930fc4a58ec38fb718549780823661d0e67740c037a222066010d10f220fa6f&amp;scene=21#wechat_redirect\">\u6570\u5b57\u5065\u5eb7\u79c1\u8463\u4f1a<\/a>\u3001<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247490039&amp;idx=1&amp;sn=d2a511cbb597cc8a94a293109ecff182&amp;chksm=eb72ab40dc05225626e3ceed82565420f25db73823ee2a332a4692ef83101826acebe335ed9c&amp;scene=21#wechat_redirect\">\u7ca4\u6e2f\u6fb3\u5927\u6e7e\u533a\u751f\u547d\u5065\u5eb7\u521b\u65b0\u8bba\u575b<\/a><\/div>\n<div>\u2606\u00a0\u53d7\u9080\u4e3a<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247491096&amp;idx=1&amp;sn=a9f63089213ee85953ae946f921fb14e&amp;chksm=eb72acafdc0525b91aac8568febadcf191747b6e158f1c29e303a067c64310adf97ddba15f0d&amp;scene=21#wechat_redirect\">\u534e\u897f\u533b\u9662<\/a>\u3001<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247489194&amp;idx=1&amp;sn=c6e4ce2a492314bcbbce328f35a96aed&amp;chksm=eb72a41ddc052d0ba20314850828f6d4c10f9402c82404146b4255c5dc9631d47583eeadb8d2&amp;scene=21#wechat_redirect\">Illumina<\/a>\u3001<a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247491709&amp;idx=1&amp;sn=7b6edbf13b6a035ed8ac75e037ced54f&amp;chksm=eb7152cadc06dbdc089785b84268aa45eee071a5b400673d46c31e5f21867719745be0c003db&amp;scene=21#wechat_redirect\">\u534e\u5927<\/a>\u3001<a 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