\u57fa\u56e0\u884c\u4e1a\u5468\u62a5 GeneMail No.95<\/div>\n
2020\u5e74\u7b2c19\u5468<\/div>\n
\u3010\u5b8f\u89c2\u73af\u5883\u3011\u56fd\u5bb6\u9ad8\u6027\u80fd\u533b\u7597\u5668\u68b0\u521b\u65b0\u4e2d\u5fc3\u843d\u6237\u6df1\u5733<\/div>\n
\u3010\u57fa\u7840\u7814\u7a76\u3011NEJM\u53d1\u5e03\u4e2d\u56fd\u8111\u5352\u4e2d\u91cd\u78c5\u7814\u7a76\u6210\u679c<\/div>\n
\u3010\u8f6c\u5316\u5e94\u7528\u3011\u5f20\u950b\u56e2\u961f\u63a8\u51fa\u65b0\u51a0\u75c5\u6bd2CRISPR\u68c0\u6d4b\u6280\u672f<\/div>\n
\u3010\u4ea7\u4e1a\u53d1\u5c55\u3011\u764c\u75c7\u65e9\u68c0\u516c\u53f8\u9ad8\u7f8e\u751f\u7269\u4e0e\u57fa\u56e0\u68c0\u6d4b\u516c\u53f8\u8bfa\u6069\u751f\u7269\u5408\u5e76<\/div>\n
\u3010\u6218\u75ab\u4e13\u9898\u3011\u65b0\u51a0\u75c5\u6bd2\u6838\u9178\u548c\u6297\u4f53\u68c0\u6d4b\u4e34\u5e8a\u5e94\u7528\u4e13\u5bb6\u5171\u8bc6\u53d1\u5e03<\/div>\n
\u66f4\u591a\u8d44\u8baf\u89c1\u57fa\u56e0\u6167GeneMail\u6b63\u6587\uff0c\u6295\u7a3f\u6216\u5408\u4f5c\u8bf7\u8054\u7cfb info@genonet.cn\u3002<\/div>\n
\u6587\u7ae0 |\u57fa\u56e0\u6167\u00a0\u00a0\u7f16\u8f91 | Whiteney\u00a0 \u5ba1\u6838 | Dylan<\/div>\n
\u00a0<\/div>\n
\u5934\u6761<\/div>\n
\u25a0\u00a0Broad\u5927\u725bAviv Regev\u51fa\u4efb\u00a0<\/div>\n
\u7f57\u6c0f\u5b50\u516c\u53f8Genentech\u7814\u53d1\u8d1f\u8d23\u4eba<\/div>\n
5\u670811\u65e5\uff0c\u7f57\u6c0f\uff08Roche\uff09\u5ba3\u5e03\uff0cAviv Regev\u5c06\u52a0\u5165\u7f57\u6c0f\u5b50\u516c\u53f8\u57fa\u56e0\u6cf0\u514b\u7814\u7a76\u4e0e\u65e9\u671f\u5f00\u53d1\u90e8\u95e8\uff08Genentech Research and Early Development, gRED\uff09\uff0c\u63a5\u66ffMichael Varney\u6210\u4e3a\u65b0\u4efb\u8d1f\u8d23\u4eba\uff0c\u5e76\u5c06\u4e8e2020\u5e748\u67081\u65e5\u6210\u4e3a\u7f57\u6c0f\u516c\u53f8\u6267\u884c\u59d4\u5458\u4f1a\u7684\u4e00\u5458\u3002<\/div>\n
Aviv Regev\u6559\u6388\u73b0\u662fMIT\u548c\u54c8\u4f5b\u5927\u5b66Broad\u7814\u7a76\u6240\u7684\u77e5\u540d\u4e13\u5bb6\uff0c\u4e5f\u662f\u56fd\u9645\u4eba\u7c7b\u7ec6\u80de\u56fe\u8c31\uff08Human Cell Atlas\uff09\u9879\u76ee\u7684\u8054\u5408\u4e3b\u5e2d\u3002Aviv Regev\u66fe\u548c\u5f20\u950b\u4e00\u8d77\u5f00\u53d1\u4e86\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\u65b9\u6cd5\uff0c\u5728\u751f\u7269\u4fe1\u606f\u3001\u673a\u5668\u5b66\u4e60\u7b97\u6cd5\u65b9\u9762\u8d21\u732e\u4e86\u8bb8\u591a\u5353\u8d8a\u7684\u6210\u679c\u3002<\/div>\n
\u57fa\u56e0\u6cf0\u514b\u662f\u5168\u7403\u77e5\u540d\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u57282009\u5e74\u4ee5468\u4ebf\u7f8e\u5143\u88ab\u7f57\u6c0f\u6536\u8d2d\u3002<\/div>\n
\u00a0<\/div>\n
\u5b8f\u89c2\u73af\u5883<\/div>\n
\u25a0\u00a0\u56fd\u5bb6\u9ad8\u6027\u80fd\u533b\u7597\u5668\u68b0\u521b\u65b0\u4e2d\u5fc3\u843d\u6237\u6df1\u5733<\/div>\n
5\u67088\u65e5\uff0c\u636e\u5e7f\u4e1c\u7701\u5de5\u4fe1\u5385\u6d88\u606f\uff0c\u56fd\u5bb6\u9ad8\u6027\u80fd\u533b\u7597\u5668\u68b0\u521b\u65b0\u4e2d\u5fc3\u83b7\u5de5\u4e1a\u548c\u4fe1\u606f\u5316\u90e8\u6279\u590d\u7ec4\u5efa\uff0c\u6b63\u5f0f\u843d\u6237\u5e7f\u4e1c\u7701\u6df1\u5733\u5e02\u3002\u8fd9\u662f\u76ee\u524d\u5168\u56fd\u7ec4\u5efa\u768416\u4e2a\u56fd\u5bb6\u5236\u9020\u4e1a\u521b\u65b0\u4e2d\u5fc3\u4e4b\u4e00\uff0c\u4e5f\u662f\u5e7f\u4e1c\u7b2c2\u5bb6\u3001\u6df1\u5733\u9996\u5bb6\u56fd\u5bb6\u5236\u9020\u4e1a\u521b\u65b0\u4e2d\u5fc3\u3002<\/div>\n
\u00a0<\/div>\n
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\u8fd1\u671f\uff0c\u601d\u8def\u8fea\u65b0\u51a0\u75c5\u6bd2\u6838\u9178\u81ea\u52a8\u5316\u63d0\u53d6\u7cfb\u7edf\uff08\u6838\u9178\u62bd\u63d0\u4eea\u548c\u914d\u5957\u7684\u8bd5\u5242\u76d2\uff09\u83b7FDA\u6279\u51c6\u3002\u636e\u6089\uff0c\u8fd9\u662f\u7b2c\u4e00\u4e2a\u540c\u65f6\u83b7\u5f97\u4e2d\u56fdNMPA\uff0c\u6b27\u76dfCE\u548c\u7f8e\u56fdFDA\u8ba4\u8bc1\u8d44\u8d28\u7684\u81ea\u52a8\u5316\u9ad8\u901a\u91cf\u75c5\u6bd2\u6838\u9178\u63d0\u53d6\u7cfb\u7edf\uff0c\u53ef\u7528\u4e8e\u670d\u52a1\u5168\u7403\u5927\u90e8\u5206\u56fd\u5bb6\u7684\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u9ad8\u901a\u91cf\u6838\u9178\u63d0\u53d6\u9700\u6c42\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0FDA\u6279\u51c6\u9488\u5bf9MET\u57fa\u56e0\u7a81\u53d8\u7684NSCLC\u9776\u5411\u836f<\/div>\n
\u7f8e\u56fd\u65f6\u95f45\u67086\u65e5\uff0cFDA\u6279\u51c6\u8bfa\u534e\uff08Novartis\uff09\u7684MET\u6291\u5236\u5242Tabrecta\uff08capmatinib\uff09\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u643a\u5e26MET\u57fa\u56e0\u5916\u663e\u5b5014\u8df3\u8dc3\u7a81\u53d8\u7684\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\uff08\u9700\u5148\u7ecfFDA\u6279\u51c6\u7684\u68c0\u6d4b\u786e\u8ba4\u57fa\u56e0\u7a81\u53d8\uff09\u3002\u8fd9\u662fFDA\u6279\u51c6\u7684\u9488\u5bf9\u8fd9\u4e00\u7279\u5b9a\u60a3\u8005\u7fa4\u7684\u9996\u6b3e\u9776\u5411\u7597\u6cd5\u3002<\/div>\n
\u00a0<\/div>\n
\u57fa\u7840\u7814\u7a76<\/div>\n
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\u6210\u679c\u520a\u767b\u5728\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b<\/div>\n
5\u67087\u65e5\uff0c\u300a\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u300b\uff08NEJM\uff09\u53d1\u8868\u4e86\u7531\u4e2d\u56fd41\u5bb6\u62e5\u6709\u9ad8\u7ea7\u5352\u4e2d\u4e2d\u5fc3\u7684\u533b\u9662\u5408\u529b\u5f00\u5c55\u7684\u201d\u4e2d\u56fd\u6025\u6027\u5927\u8840\u7ba1\u95ed\u585e\u6027\u7f3a\u8840\u6027\u5352\u4e2d\u76f4\u63a5\u52a8\u8109\u6cbb\u7597\u7684\u7597\u6548\u8bc4\u4f30\uff08DIRECT-MT\uff09\u201c \u8bd5\u9a8c\u6210\u679c\u3002\u5171\u5165\u7ec4\u4e86656\u540d\u540c\u65f6\u7b26\u5408\u9759\u8109\u6eb6\u6813\u4e0e\u673a\u68b0\u53d6\u6813\u8981\u6c42\u7684\u60a3\u8005\uff0c\u8bc1\u5b9e\u5bf9\u524d\u5faa\u73af\u5927\u8840\u7ba1\u95ed\u585e\u7684\u6025\u6027\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u60a3\u8005\uff0c\u91c7\u53d6\u76f4\u63a5\u8840\u7ba1\u5185\u673a\u68b0\u53d6\u6813\uff0c\u4e34\u5e8a\u83b7\u76ca\u4e0d\u52a3\u4e8e\u201c\u9759\u8109\u6eb6\u6813+\u673a\u68b0\u53d6\u6813\u201d\u7684\u7b56\u7565\u3002<\/div>\n
\u3010\u7f16\u8005\u6309\u3011\u8111\u5352\u4e2d\uff08cerebral+stroke\uff09\uff0c\u5373\u5e38\u8bf4\u7684\u201c\u4e2d\u98ce\u201d\uff0c\u662f\u6211\u56fd\u57ce\u5e02\u548c\u519c\u6751\u4eba\u53e3\u7b2c\u4e00\u4f4d\u81f4\u6b8b\u548c\u6b7b\u4ea1\u539f\u56e0\u3002\u8111\u5352\u4e2d\u662f\u4e00\u79cd\u6025\u6027\u8111\u8840\u7ba1\u75be\u75c5\uff0c\u5305\u62ec\u7f3a\u8840\u6027\u548c\u51fa\u8840\u6027\u5352\u4e2d\uff1b\u5176\u4e2d\uff0c\u7f3a\u8840\u6027\u5352\u4e2d\u5360\u6bd460%\uff5e70%\u3002\u6b64\u6b21\u8bd5\u9a8c\u7684\u6210\u529f\uff0c\u6709\u671b\u6539\u5199\u8111\u5352\u4e2d\u6551\u6cbb\u7684\u4e34\u5e8a\u6307\u5357\uff0c\u5e2e\u52a9\u4f18\u5316\u6cbb\u7597\u6d41\u7a0b\u3002\u6b64\u524d\uff0c\u4e2d\u534e\u533b\u5b66\u4f1a\u795e\u7ecf\u75c5\u5b66\u5206\u4f1a\u5148\u540e\u64b0\u5199\u53d1\u5e03\u4e862014\u7248\u30012018\u7248\u53ca2019\u7248\u4e2d\u56fd\u6025\u6027\u671f\u7f3a\u8840\u6027\u8111\u5352\u4e2d\u8bca\u6cbb\u6307\u3002<\/div>\n
\u00a0<\/div>\n
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\u65b0\u51a0\u75c5\u6bd2\u706d\u6d3b\u75ab\u82d7\u5728\u6052\u6cb3\u7334\u6a21\u578b\u4e2d\u5b89\u5168\u6709\u6548<\/div>\n
5\u67086\u65e5\uff0c\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u533b\u5b66\u5b9e\u9a8c\u52a8\u7269\u7814\u7a76\u6240\u79e6\u5ddd\u56e2\u961f\u3001CDC\u4f20\u67d3\u75c5\u9884\u9632\u63a7\u5236\u6240\u7b49\u591a\u5bb6\u5355\u4f4d\uff0c\u8054\u5408\u5728Science\u4e0a\u53d1\u5e03\u4e86\u9996\u4e2a\u516c\u5f00\u62a5\u9053\u7684\u65b0\u51a0\u75ab\u82d7\u52a8\u7269\u5b9e\u9a8c\u7814\u7a76\u7ed3\u679c\uff0c\u8868\u660e\u5019\u9009\u75ab\u82d7\u5728\u6052\u6cb3\u7334\u4e2d\u5177\u6709\u5b89\u5168\u6027\u3002<\/div>\n
\u636e\u6089\uff0c4\u670813\u65e5\uff0c\u8be5\u75ab\u82d7\u5df2\u83b7NMPA\u6279\u51c6\u8fdb\u5165\u4e34\u5e8a\u7814\u7a76\uff1b4\u670816\u65e5\uff0c\u2160\u671f\u4e34\u5e8a\u7814\u7a76\u5728\u6c5f\u82cf\u5f90\u5dde\u7762\u5b81\u6b63\u5f0f\u542f\u52a8\uff0c\u9996\u6279\u5fd7\u613f\u8005\u5df2\u987a\u5229\u5165\u7ec4\u5e76\u5b8c\u6210\u9996\u9488\u75ab\u82d7\u63a5\u79cd\u3002<\/div>\n
\u00a0<\/div>\n
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\u8054\u7cfb\u65b9\u5f0f\uff1a400-088-7466<\/div>\n\n
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<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u25a0\u00a0\u963b\u65ad\u65b0\u51a0\u75c5\u6bd2\u611f\u67d3\u7684\u5168\u4eba\u6e90\u5355\u6297\u7814\u7a76\u53d1\u8868<\/div>\n
5\u67084\u65e5\uff0c\u548c\u94c2\u533b\u836f\u3001\u8377\u5170\u4e4c\u5f97\u52d2\u652f\u5927\u5b66\u548c\u4f0a\u62c9\u65af\u59c6\u65af\u5927\u5b66\u533b\u5b66\u4e2d\u5fc3\u7b49\u7684\u79d1\u5b66\u5bb6\u8054\u5408\u5728Nature Communications\u00a0\u53d1\u8868\u8bba\u6587\uff0c\u4ecb\u7ecd\u4e86\u4e00\u79cd\u80fd\u591f\u963b\u65ad\u65b0\u51a0\u75c5\u6bd2\u611f\u67d3\u7684\u5168\u4eba\u6e90\u5355\u514b\u9686\u6297\u4f53\uff0c\u5b83\u80fd\u5728\u7ec6\u80de\u7cfb\u91cc\u6709\u6548\u4e2d\u548c\u65b0\u51a0\u75c5\u6bd2\u3002\u7531\u4e8e\u5b83\u9776\u5411\u4e00\u4e2a\u65b0\u51a0\u75c5\u6bd2\u548cSARS\u75c5\u6bd2\u5171\u7528\u7684\u4fdd\u5b88\u8868\u4f4d\uff0c\u8fd9\u6b3e\u6297\u4f53\u6709\u671b\u5bf9\u672a\u6765\u53ef\u80fd\u7684\u540c\u4e9a\u5c5e\u51a0\u72b6\u75c5\u6bd2\u8d77\u5230\u9884\u9632\u548c\u6cbb\u7597\u7684\u4f5c\u7528\u3002<\/div>\n
\u00a0<\/div>\n
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\u65b0\u4e00\u4ee3\u65b0\u51a0\u75c5\u6bd2CRISPR\u68c0\u6d4b\u6280\u672f<\/div>\n
5\u67086\u65e5\uff0c\u5f20\u950b\u6559\u6388\u3001Broad\u7814\u7a76\u6240\u548c\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u9ea6\u6208\u6587\u8111\u79d1\u5b66\u7814\u7a76\u6240\u8054\u5408\u516c\u5e03\u4e86\u5f00\u53d1\u7684\u65b0\u4e00\u4ee3\u65b0\u51a0\u75c5\u6bd2CRISPR\u68c0\u6d4b\u6280\u672f\u7684\u5b9e\u9a8c\u6d41\u7a0bSTOP\uff08SHERLOCK Testing in One Pot\uff09\u3002\u5b83\u4e0d\u9700\u4ece\u60a3\u8005\u6837\u672c\u4e2d\u7eaf\u5316RNA\uff0c\u4e14\u5c06\u68c0\u6d4b\u65b0\u51a0\u75c5\u6bd2\u6240\u9700\u7684\u5316\u5b66\u53cd\u5e94\u6b65\u9aa4\u5728\u4e00\u4e2a\u8bd5\u7ba1\u4e2d\u5b8c\u6210\u3002\u76ee\u524d\u8be5\u68c0\u6d4b\u65b9\u6cd5\u8fd8\u672a\u83b7\u5f97FDA\u6279\u51c6\uff0c\u5c1a\u4e0d\u80fd\u7528\u4e8e\u4e34\u5e8a\u4e0a\u5bf9\u65b0\u51a0\u75c5\u6bd2\u611f\u67d3\u7684\u8bca\u65ad\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0FDA\u5206\u522b\u6388\u4e88Sansure Biotech\u3001UTHSC<\/div>\n
\u5f00\u53d1\u7684\u65b0\u51a0\u75c5\u6bd2\u68c0\u6d4b\u4ea7\u54c1\u7d27\u6025\u4f7f\u7528\u8bb8\u53ef<\/div>\n
\u7f8e\u56fd\u65f6\u95f45\u67085\u65e5\uff0cFDA\u6388\u4e882\u5bb6\u673a\u6784\u5f00\u53d1\u7684\u57fa\u4e8ePCR\u7684SARS-CoV-2\u68c0\u6d4b\u4ea7\u54c1\u7d27\u6025\u4f7f\u7528\u6388\u6743\uff0c\u5206\u522b\u662f\u4e2d\u56fdSansure Biotech\u548c\u7f8e\u56fd\u7530\u7eb3\u897f\u5927\u5b66\u5065\u5eb7\u79d1\u5b66\u4e2d\u5fc3\uff08UTHSC\uff09\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u541b\u5b9e\u751f\u7269&\u793c\u6765\u516c\u53f8<\/div>\n
\u8fbe\u6210$2.55\u4ebf\u65b0\u51a0\u6297\u4f53\u6388\u6743<\/div>\n
5\u67084\u65e5\uff0c\u541b\u5b9e\u751f\u7269\u4e0e\u793c\u6765\u516c\u53f8\u7b7e\u7f72\u4e86\u300a\u7814\u53d1\u5408\u4f5c\u548c\u8bb8\u53ef\u534f\u8bae\u300b\uff0c\u5c06\u5408\u4f5c\u7814\u53d1\u53ca\u5546\u4e1a\u5316SARS-CoV-2\u4e2d\u548c\u6297\u4f53\uff08\u7b80\u79f0\uff1a\u541b\u5b9e\u65b0\u51a0\u6297\u4f53\uff0c\u4ea7\u54c1\u4ee3\u53f7\uff1aJS016\uff09\u3002<\/div>\n
\u636e\u534f\u8bae\uff0c\u793c\u6765\u516c\u53f8\u5c06\u88ab\u6388\u4e88\u5728\u5927\u4e2d\u534e\u5730\u533a\u5916\u5bf9JS016\u5f00\u5c55\u7814\u53d1\u6d3b\u52a8\u3001\u751f\u4ea7\u548c\u9500\u552e\u7684\u72ec\u5360\u8bb8\u53ef\u3002\u4e3a\u6b64\uff0c\u793c\u6765\u516c\u53f8\u5c06\u5411\u541b\u5b9e\u751f\u7269\u652f\u4ed81000\u4e07\u7f8e\u5143\u9996\u4ed8\u6b3e\uff0c\u5e76\u5728\u6bcf\u4e00\u4e2aJS016\uff08\u5355\u7528\u6216\u7ec4\u5408\uff09\u5b9e\u73b0\u89c4\u5b9a\u7684\u91cc\u7a0b\u7891\u4e8b\u4ef6\u540e\uff0c\u5411\u541b\u5b9e\u751f\u7269\u652f\u4ed8\u6700\u9ad82.45\u4ebf\u7f8e\u5143\u7684\u91cc\u7a0b\u7891\u6b3e\uff0c\u5916\u52a0\u8be5\u4ea7\u54c1\u9500\u552e\u51c0\u989d\u4e24\u4f4d\u6570\u767e\u5206\u6bd4\u7684\u9500\u552e\u5206\u6210\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u00a0\u71c3\u77f3\u533b\u5b66\u542f\u52a8\u4e2d\u56fd\u9996\u4e2a<\/div>\n
\u8d85\u4e07\u4eba\u524d\u77bb\u6027\u6cdb\u764c\u79cd\u65e9\u68c0\u7814\u7a76<\/div>\n
5\u67087\u65e5\uff0c\u71c3\u77f3\u533b\u5b66\u5ba3\u5e03\u6b63\u5f0f\u542f\u52a8\u764c\u75c7\u65e9\u68c0(Early Detection)\u9886\u57df\u91cc\u7a0b\u7891\u7814\u7a76\u201cPREDICT\u201d (Pan-CanceR Early DetectIon ProjeCT)\u3002PREDICT\u662f\u4e00\u9879\u91c7\u7528\u71c3\u77f3\u533b\u5b66\u81ea\u4e3b\u5f00\u53d1\u7684ELSA-seq\u6280\u672f\uff0c\u57fa\u4e8ecfDNA (cell-free DNA)\u7532\u57fa\u5316\u68c0\u6d4b\u7684\u65e9\u671f\u764c\u75c7\u68c0\u6d4b\u6a21\u578b\u5728\u591a\u764c\u79cd\u4e2d\u7684\u63a2\u7d22\u53ca\u9a8c\u8bc1\u7684\u524d\u77bb\u6027\u3001\u591a\u4e2d\u5fc3\u7814\u7a76\u3002<\/div>\n
\u8fd9\u662f\u56fd\u5185\u8fc4\u4eca\u4e3a\u6b62\u6700\u5927\u89c4\u6a21\u7684\u524d\u77bb\u6027\u3001\u6cdb\u764c\u79cd\u65e9\u68c0\u7814\u7a76\uff0c\u7814\u7a76\u9884\u671f\u7eb3\u5165\u8d85\u8fc714000\u4f8b\u53d7\u8bd5\u8005\u3002\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u4e2d\u5c71\u533b\u9662\u4f5c\u4e3aPREDICT\u7814\u7a76\u7684\u7275\u5934\u5355\u4f4d\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u6a0a\u5609\u9662\u58eb\u62c5\u4efb\u4e3b\u8981\u7814\u7a76\u8005\u3002<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u53d1\u5c55<\/div>\n
\u25a0\u00a0\u9ad8\u7f8e\u751f\u7269\u4e0e\u8bfa\u6069\u751f\u7269\u5408\u5e76<\/div>\n
\u52a0\u901f\u764c\u75c7\u65e9\u68c0\u7814\u53d1\u53ca\u63a8\u5e7f<\/div>\n
5\u67084\u65e5\uff0c\u9ad8\u7f8e\u751f\u7269\uff08\u764c\u75c7\u65e9\u68c0\u516c\u53f8\uff09\u4e0e\u8bfa\u6069\u751f\u7269\uff08\u57fa\u56e0\u68c0\u6d4b\u53caIVD\u670d\u52a1\u63d0\u4f9b\u5546\uff09\u5b8c\u6210\u5408\u5e76\u53ca\u7b7e\u7f72\u534f\u8bae\u3002\u5408\u5e76\u540e\u7684\u6bcd\u516c\u53f8\u5c06\u4f7f\u7528\u9ad8\u7f8e\u751f\u7269\u54c1\u724c\uff0c\u5e76\u5c06\u4fdd\u7559\u8bfa\u6069\u751f\u7269\u540d\u79f0\u4f5c\u4e3a\u65d7\u4e0b\u5b50\u54c1\u724c\u4f7f\u7528\u3002\u6b64\u6b21\u5408\u5e76\u7531\u51ef\u4e58\u8d44\u672c\u62c5\u4efb\u8d22\u52a1\u987e\u95ee\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u672c\u54683\u8d77\u878d\u8d44\u4e8b\u4ef6<\/div>\n
5\u67088\u65e5\uff0c\u5357\u4eac\u8bfa\u552f\u8d5e\u751f\u7269\u5ba3\u5e03\u5df2\u4e8e\u8fd1\u65e5\u5b8c\u62105.5\u4ebf\u5143\u4eba\u6c11\u5e01C\u8f6e\u878d\u8d44\u3002\u672c\u8f6e\u878d\u8d44\u7531\u4e2d\u56fd\u4eba\u5bff\u5927\u5065\u5eb7\u57fa\u91d1\u72ec\u5bb6\u9886\u6295\uff0c\u590f\u5c14\u5df4\u6295\u8d44\u7b49\u53c2\u4e0e\u8ddf\u6295\u3002<\/div>\n
\u7f8e\u56fd\u65f6\u95f45\u67086\u65e5\uff0c\u764c\u75c7\u65e9\u7b5b\u516c\u53f8GRAIL\u5ba3\u5e03\u5b8c\u62103.9\u4ebf\u7f8e\u5143D\u8f6e\u878d\u8d44\u3002\u672c\u8f6e\u878d\u8d44\u7531\u52a0\u62ff\u5927\u516c\u5171\u90e8\u95e8\u517b\u8001\u91d1\u6295\u8d44\u59d4\u5458\u4f1a\uff08PSP Investments\uff09\u3001\u52a0\u62ff\u5927\u517b\u8001\u91d1\u6295\u8d44\u59d4\u5458\u4f1a\uff08CPP Investments\uff09\u548cIllumina\u7b49\u6295\u8d44\u3002<\/div>\n
\u7f8e\u56fd\u65f6\u95f45\u67085\u65e5\uff0c\u6838\u9178\u5206\u6790\u8bbe\u5907\u63d0\u4f9b\u5546Tangen Biosciences\u00a0\u5ba3\u5e03\u4ece\u7f8e\u56fd\u536b\u751f\u4e0e\u516c\u5171\u670d\u52a1\u90e8\uff08BARDA\uff09\u83b7\u5f97330\u4e07\u7f8e\u5143\u7684\u989d\u5916\u6295\u8d44\uff0c\u7528\u4e8e\u7ee7\u7eed\u5f00\u53d1\u5176\u5206\u5b50\u8bca\u65ad\u5e73\u53f0\uff0c\u4ee5\u68c0\u6d4b\u8840\u6db2\u4e2d\u7684\u70ad\u75bd\u5e76\u5f00\u5c55\u4f20\u67d3\u75c5\u68c0\u6d4b\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0Illumina2020\u5e74\u7b2c\u4e00\u5b63\u5ea6\u6536\u5165\u589e\u957f2\uff05<\/div>\n
\u8fd1\u671f\uff0cIllumina\u53d1\u5e03\u76842020\u5e74\u7b2c\u4e00\u5b63\u5ea6\u8d22\u62a5\u663e\u793a\uff0c\u603b\u6536\u5165\u4e3a8.59\u4ebf\u7f8e\u5143\uff0c\u540c\u6bd42019\u5e74\u7b2c\u4e00\u5b63\u5ea6\u589e\u957f2\uff05\u3002\u6d4b\u5e8f\u6536\u5165\u603b\u8ba17.6\u4ebf\u7f8e\u5143\uff1a\u4eea\u5668\u6536\u5165\u4e3a7900\u4e07\u7f8e\u5143\uff0c\u540c\u6bd4\u4e0b\u964d\u4e8625\uff05\uff1b\u8017\u6750\u6536\u5165\u4e3a5.53\u4ebf\u7f8e\u5143\uff0c\u6bd42019\u5e74\u7b2c\u4e00\u5b63\u5ea6\u589e\u957f15\uff05\u3002<\/div>\n
\u4ece\u5730\u533a\u4e0a\u770b\uff0c\u4e2d\u56fd\u6536\u5165\u4e3a8400\u4e07\u7f8e\u5143\uff1b\u6b27\u6d32\u3001\u4e2d\u4e1c\u548c\u975e\u6d32\u7684\u6536\u5165\u4e3a2.21\u4ebf\u7f8e\u5143\uff1b\u7f8e\u6d32\u6536\u5165\u4e3a4.77\u4ebf\u7f8e\u5143\uff1b\u4e9a\u592a\u5730\u533a\u548c\u65e5\u672c\u7684\u6536\u5165\u8fbe\u5230\u4e86\u521b\u7eaa\u5f55\u76847700\u4e07\u7f8e\u5143\uff0c\u662f\u8be5\u5730\u533a\u6709\u53f2\u4ee5\u6765\u6700\u9ad8\u7684\u603b\u6536\u5165\u3002<\/div>\n
\u6218\u75ab\u4e13\u9898<\/div>\n
\u00a0<\/div>\n
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5\u67089\u65e5\uff0c\u4e0a\u6d77\u5e02\u533b\u5b66\u4f1a\u68c0\u9a8c\u533b\u5b66\u5206\u4f1a\u5728\u300a\u56fd\u9645\u68c0\u9a8c\u533b\u5b66\u6742\u5fd7\u300b\u53d1\u8868\u300a\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u6838\u9178\u548c\u6297\u4f53\u68c0\u6d4b\u4e34\u5e8a\u5e94\u7528\u4e13\u5bb6\u5171\u8bc6\u300b\u3002\u8be5\u5171\u8bc6\u4ee5\u5bf9\u65b0\u51a0\u75c5\u6bd2\u4e34\u5e8a\u5b9e\u9a8c\u5ba4\u68c0\u6d4b\u3001\u4e34\u5e8a\u5e94\u7528\u548c\u751f\u7269\u5b89\u5168\u63d0\u4f9b\u6709\u6307\u5bfc\u6027\u7684\u5efa\u8bae\uff1b\u9002\u7528\u4e8e\u4ece\u4e8b\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u6838\u9178\u548c\u8840\u6e05\u6297\u4f53\u68c0\u6d4b\u7684\u4e34\u5e8a\u5b9e\u9a8c\u5ba4\uff0c\u65e8\u5728\u89c4\u8303\u6211\u56fd\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u6838\u9178\u548c\u6297\u4f53\u68c0\u6d4b\u65b9\u6cd5\u4e0e\u6d41\u7a0b\uff0c\u4e3a\u4e34\u5e8a\u63d0\u4f9b\u89c4\u8303\u53ef\u9760\u7684\u68c0\u6d4b\u7ed3\u679c\u4e0e\u5408\u7406\u7684\u62a5\u544a\u89e3\u8bfb\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0 \u536b\u5065\u59d4\u5ba3\u5e03\u5168\u56fd\u6240\u6709\u53bf\u57df\u5747\u8c03\u6574\u4e3a\u4f4e\u98ce\u9669<\/div>\n
5\u67087\u65e5\uff0c\u56fd\u52a1\u9662\u8054\u9632\u8054\u63a7\u673a\u5236\u53d1\u5e03\u4f1a\u4e0a\uff0c\u56fd\u5bb6\u536b\u5065\u59d4\u65b0\u95fb\u53d1\u8a00\u4eba\u7c73\u950b\u8868\u793a\uff0c\u5373\u65e5\u8d77\u5168\u56fd\u6240\u6709\u53bf\u57df\u5747\u8c03\u6574\u4e3a\u4f4e\u98ce\u9669\u3002\u4f46\u65b0\u51a0\u80ba\u708e\u75ab\u60c5\u8fd8\u6709\u5f88\u5927\u4e0d\u786e\u5b9a\u6027\uff0c\u8981\u7ee7\u7eed\u505a\u597d\u60a3\u8005\u6551\u6cbb\u548c\u5eb7\u590d\u7ba1\u7406\uff0c\u843d\u5b9e\u5e38\u6001\u5316\u9632\u63a7\u4e3e\u63aa\uff0c\u4e25\u9632\u75ab\u60c5\u53cd\u5f39\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0Nature\u5168\u9762\u9610\u8ff0\uff1a<\/div>\n
\u5bfc\u81f4\u65b0\u51a0\u75c5\u6bd2\u5927\u6d41\u884c\u7684\u590d\u6742\u751f\u7269\u5b66<\/div>\n
5\u67084\u65e5\uff0cNature \u4ee5\u51a0\u72b6\u75c5\u6bd2\u5bb6\u65cf\u6210\u5458\u7684\u5404\u79cd\u8d44\u6599\u3001\u53ef\u80fd\u5bfc\u81f41889-1990\u5e74\u5168\u7403\u8d85\u8fc7100\u4e07\u4eba\u6b7b\u4ea1\u7684OC43\u51a0\u72b6\u75c5\u6bd2\u4f5c\u4e3a\u53c2\u8003\u6a21\u578b\u7684\u4fe1\u606f\uff0c\u5168\u9762\u9610\u8ff0\u4e86\u5bfc\u81f4\u65b0\u51a0\u75c5\u6bd2\u5927\u6d41\u884c\u7684\u590d\u6742\u751f\u7269\u5b66\u3002<\/div>\n
\u5305\u62ec\uff1a<\/div>\n
\u2460\u00a0\u00a0\u65b0\u51a0\u75c5\u6bd2\u662f\u5177\u6709\u57fa\u56e0\u7ec4\u6821\u5bf9\u673a\u5236\u7684RNA\u75c5\u6bd2\u4e4b\u4e00\uff0c\u8fd9\u79cd\u673a\u5236\u53ef\u9632\u6b62\u75c5\u6bd2\u79ef\u7d2f\u7684\u53ef\u80fd\u524a\u5f31\u81ea\u8eab\u7684\u7a81\u53d8\u3002<\/div>\n
\u2461 \u65b0\u51a0\u75c5\u6bd2\u4f3c\u4e4e\u5229\u7528\u5bbf\u4e3b\u4f53\u5185\u7684furin\u9176\u6765\u5207\u5272\u75c5\u6bd2\u7684S\u86cb\u767d\uff0cfurin\u5728\u547c\u5438\u9053\u4e2d\u542b\u91cf\u4e30\u5bcc\uff0c\u4e14\u904d\u5e03\u5168\u8eab\u3002<\/div>\n
\u2462\u00a0\u00a0\u65b0\u51a0\u75c5\u6bd2\u80fd\u6210\u529f\u611f\u67d3\u65b0\u7ec6\u80de\uff0c\u7e41\u6b96\u5e76\u4f20\u64ad\u7ed9\u65b0\u7ec6\u80de\uff0c\u5b83\u662f\u5426\u4f1a\u4f24\u5bb3\u5bbf\u4e3b\u5e76\u4e0d\u91cd\u8981\u3002<\/div>\n
\u6587\u732e\u94fe\u63a5\uff1a<\/div>\n
https:\/\/www.nature.com\/articles\/d41586-020-01315-7<\/div>\n
\u3010\u58f0\u660e\u3011\u6211\u4eec\u79c9\u6301\u4e13\u4e1a\u3001\u4e13\u6ce8\u3001\u8d4b\u80fd\u7684\u7406\u5ff5\u6536\u96c6\u3001\u5206\u6790\u6216\u53d1\u5e03\u4fe1\u606f\uff0c\u4f46\u7531\u4e8e\u65f6\u6548\u6027\u53ca\u884c\u4e1a\u7279\u6b8a\u6027\uff0c\u6240\u520a\u767b\u5185\u5bb9\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u4e0d\u4f5c\u4e3a\u51b3\u7b56\u4f9d\u636e\uff1b\u4ee5\u4e0a\u4fe1\u606f\u4e0d\u4ee3\u8868\u57fa\u56e0\u89c2\u70b9\uff1b\u201c\u57fa\u56e0\u6167\u201d\u520a\u767b\u7684\u539f\u521b\u5185\u5bb9\u7684\u77e5\u8bc6\u4ea7\u6743\u4e3a\u201c\u57fa\u56e0\u6167\u201d\u5546\u6807\u53ca\u76f8\u5173\u6743\u5229\u4eba\u6240\u6709\uff1b\u8f6c\u8f7d\u8bf7\u7533\u8bf7\u5e76\u6ce8\u660e\u6765\u6e90\u3002\u6b22\u8fce\u4e2a\u4eba\u53ca\u673a\u6784\u6295\u7a3f\u53ca\u5408\u4f5c\u3002<\/div>\n
\u5f80\u671f\u63a8\u8350<\/div>\n
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