{"id":9091,"date":"2020-06-15T08:03:16","date_gmt":"2020-06-15T00:03:16","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100013659&idx=1&sn=31d80adb44b673890038b6e748053199&chksm=6b7144ec5c06cdfa78a89ec6c65a2b66e54a2fe9c1d7841c8ed17479f2378d9ad318cc9a88d0#rd"},"modified":"2026-04-02T09:49:27","modified_gmt":"2026-04-02T01:49:27","slug":"5510250","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2020\/06\/15\/5510250\/","title":{"rendered":"\u57fa\u56e0\u5185\u53c2\u4e28\u57fa\u56e0\u4ea7\u4e1a\u8d44\u672c\u5316\u4e95\u55b7\uff1a1\u8d77\u4e0a\u5e02\uff0c2\u8d77\u5e76\u8d2d\uff0c7\u8d77\u878d\u8d44"},"content":{"rendered":"

<\/p>\n

\u57fa\u56e0\u5185\u53c2\u4e28GeneMail 100\u671f<\/div>\n
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Anyway\uff0c\u71c3\u77f3\u7684\u4e0a\u5e02\u5bf9\u80bf\u7624\u8d5b\u9053\u548c\u57fa\u56e0\u884c\u4e1a\u90fd\u662f\u4e00\u5242\u5f3a\u5fc3\u9488\u3002\u7279\u522b\u662f\u6070\u9022\u521b\u4e1a\u677f\u6ce8\u518c\u5236\u843d\u5730\uff08\u89c1\u4e0b\u6587\uff09\u3002\u540c\u65f6\uff0c\u80bf\u7624\u57fa\u56e0\u8d5b\u9053\u83b7\u76ca\u540c\u65f6\u5c06\u79ef\u7d2f\u4e00\u5b9a\u7a0b\u5ea6\u7684\u540c\u8d28\u5316\uff08\u4f8b\u5982\u80ba\u764c\u4ea7\u54c1\uff09\u503c\u5f97\u8b66\u60d5\u3002<\/div>\n
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\u79d1\u6280\u521b\u65b0<\/div>\n
\u25a0 \u53d1\u73b0\u65b0\u51a0\u7279\u5f02\u6027\u7684\u57fa\u56e0\u53d8\u5f02<\/div>\n
\u8fd1\u65e5\uff0c\u6765\u81ea\u5fb7\u56fd\u7b49\u591a\u56fd\u7684\u56e2\u961f\u901a\u8fc7GWAS\u7814\u7a76\uff0c\u5206\u6790\u4e861500\u591a\u4f8b\u4f4f\u9662COVID-19\u60a3\u8005\u548c2200\u591a\u4f8b\u5065\u5eb7\u5bf9\u7167\u8005\u7684\u6837\u672c\u3002\u7ed3\u679c\u663e\u793a\uff0c\u5728\u547c\u5438\u8870\u7aed\u7684COVID-19\u60a3\u8005\u4e2d\uff0cABO\u8840\u578b\u57fa\u56e0\u5ea7\u548c\u4eba\u7c7b3\u53f7\u67d3\u8272\u4f53\u57fa\u56e0\u7c07\u4e2d\u7684\u53d8\u5f02\u6bd4\u666e\u901a\u4eba\u7fa4\u66f4\u4e3a\u666e\u904d\uff0c\u8fd9\u4e00\u53d1\u73b0\u6216\u6709\u52a9\u4e8e\u6307\u5bfc\u9488\u5bf9\u91cd\u75c7COVID-19\u75c5\u7406\u5b66\u7684\u9776\u5411\u7814\u7a76\u3002<\/div>\n
\u25a0\u00a0\u57fa\u56e0\u7f16\u8f91\u6062\u590d\u8033\u804b\u5c0f\u9f20\u542c\u529b<\/div>\n
Science Translational Medicine\u00a0\u6742\u5fd7\u520a\u6587\uff0c\u5218\u5982\u8c26\uff08David Liu\uff09\u56e2\u961f\u901a\u8fc7\u53ccAAV\u8f7d\u4f53\u9012\u9001\u5355\u78b1\u57fa\u7f16\u8f91\u5668\uff0c\u6062\u590d\u4e86Tmc1\u57fa\u56e0\u9690\u6027\u7a81\u53d8\u5bfc\u81f4\u7684\u5b8c\u5168\u8033\u804b\u5c0f\u9f20\u7684\u542c\u529b\u3002\u7ecf\u8fc7\u7f16\u8f91\u7684\u5c0f\u9f20\u5177\u6709\u4fdd\u5b58\u5b8c\u597d\u7684\u6bdb\u7ec6\u80de\u5f62\u6001\u548c\u4fe1\u53f7\u8f6c\u5bfc\u3002\u8fd9\u662f\u4eba\u7c7b\u9996\u6b21\u901a\u8fc7\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u89e3\u51b3\u9690\u6027\u9057\u4f20\u7a81\u53d8\u5bfc\u81f4\u7684\u9057\u4f20\u75be\u75c5\u3002<\/div>\n
\u25a0\u00a0\u75c5\u6bd2\u611f\u67d3\u53f2\u6216\u53ef\u4f5c\u4e3a\u809d\u764c\u65e9\u8bca\u7684\u5de5\u5177<\/div>\n
6\u670810\u65e5\uff0c\u7f8e\u56fdNIH\u738b\u5fc3\u4f1f\u6559\u6388\u548c\u5408\u4f5c\u8005\u5728Cell\u4e0a\u520a\u6587\uff0c\u63ed\u793a\u4e86\u75c5\u6bd2\u611f\u67d3\u53f2\u5bf9\u65e9\u671f\u809d\u764c\u9884\u6d4b\u7684\u5f71\u54cd\u3002\u57fa\u4e8e\u5bf9\u5927\u89c4\u6a21\u5317\u7f8e\u809d\u764c\u75c5\u4eba\u7684\u75c5\u6bd2\u7ec4\u7814\u7a76\uff0c\u63ed\u793a\u4e86\u75c5\u6bd2\u7ec4\u611f\u67d3\u53f2\u6216\u53ef\u4ee5\u4f5c\u4e3a\u809d\u764c\u65e9\u671f\u8bca\u65ad\u7684\u6f5c\u5728\u5de5\u5177\uff0c\u4e5f\u4e3a\u63d0\u51fa\u5229\u7528\u4e2a\u4f53\u75c5\u6bd2\u611f\u67d3\u53f2\u4f5c\u4e3a\u9884\u6d4b\u65e9\u671f\u764c\u75c7\u7684\u65b0\u89c2\u70b9\u63d0\u4f9b\u4e86\u6709\u6548\u7684\u79d1\u5b66\u4f9d\u636e\u3002<\/div>\n
\u25a0\u00a0circRNA\u4e0e\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u75c5\u53d8\u673a\u5236\u6709\u5173<\/div>\n
\u8fd1\u65e5\uff0cThe Journal of Clinical Investigation\u520a\u6587\uff0c\u8bc1\u5b9e\u4e86 circRNA\u5728\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u75c5\u53d8\uff08DR\uff09\u4e2d\u4ecb\u5bfc\u7684\u5468\u7ec6\u80de\u751f\u7269\u5b66\u7684\u673a\u5236\u3002DR\u662f\u5904\u4e8e\u5de5\u4f5c\u5e74\u9f84\u7684\u6210\u5e74\u4eba\u5931\u660e\u7684\u4e3b\u8981\u539f\u56e0\uff0c\u7814\u7a76\u8868\u660e\uff0c\u8bf1\u5bfccZNF532\u6216\u62ee\u6297miR-29a-3p\u53ef\u80fd\u6210\u4e3a\u5c06\u6765\u6cbb\u7597DR\u7684\u65b0\u65b9\u6cd5\u3002<\/div>\n
\u25a0\u00a0\u901a\u8fc7\u5e72\u7ec6\u80de\u5efa\u7acb\u4eba\u7c7b\u80da\u80ce\u4e09\u7ef4\u7ec4\u7ec7\u6a21\u578b<\/div>\n
6 \u6708 11 \u65e5\uff0cNature\u6742\u5fd7\u8bba\u6587\u8868\u793a\uff1a\u82f1\u56fd\u5251\u6865\u5927\u5b66\u548c\u8377\u5170\u591a\u4f4d\u79d1\u5b66\u5bb6\u901a\u8fc7\u4eba\u7c7b\u80da\u80ce\u53d1\u80b2\u5e72\u7ec6\u80de\uff0c\u5efa\u7acb\u4e86\u4e00\u79cd\u6a21\u62df\u4eba\u7c7b\u65e9\u671f\u80da\u80ce\u53d1\u80b2\u7684\u65b0\u578b\u4e09\u7ef4\u7ec4\u7ec7\u57f9\u517b\u6a21\u578b\uff0c\u6216\u6709\u52a9\u589e\u8fdb\u5bf9\u4eba\u7c7b\u65e9\u671f\u80da\u80ce\u53d1\u80b2\u8fd9\u4e00\u91cd\u8981\u53d1\u80b2\u9636\u6bb5\u7684\u7406\u89e3\u3002\u8fd9\u4e00\u91cd\u5927\u7a81\u7834\u5c06\u6709\u52a9\u4e8e\u63ed\u793a\u51fa\u751f\u7f3a\u9677\u548c\u4e0d\u5b55\u7684\u539f\u56e0\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u591a\u80fd\u5e72\u7ec6\u80de\u53ef\u80fd\u89e3\u51b3\u8131\u53d1\u95ee\u9898<\/div>\n
6\u67083\u65e5\uff0cNature\u520a\u6587\uff0c\u6ce2\u58eb\u987f\u513f\u7ae5\u533b\u9662\u548c\u54c8\u4f5b\u533b\u5b66\u9662\u7b49\u7814\u7a76\u673a\u6784\u7684\u79d1\u7814\u4eba\u5458\u5229\u7528\u591a\u80fd\u5e72\u7ec6\u80de\uff0c\u57f9\u80b2\u51fa\u4e86\u5305\u542b\u6bdb\u56ca\u7b49\u9644\u5c5e\u7ed3\u6784\u7684\u76ae\u80a4\u7c7b\u5668\u5b98\u3002\u800c\u4e14\uff0c\u901a\u8fc7\u5c0f\u9f20\u5b9e\u9a8c\uff0c\u4e00\u534a\u4ee5\u4e0a\u7684\u79fb\u690d\u4e2d\u7c7b\u5668\u5b98\u90fd\u957f\u51fa\u4e86\u6bdb\u53d1\u3002\u79d1\u5b66\u5bb6\u8868\u793a\u8fd9\u9879\u7814\u7a76\u5bf9\u4e8e\u89e3\u51b3\u8131\u53d1\u95ee\u9898\u548c\u690d\u53d1\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002<\/div>\n
\u8f6c\u5316\u5e94\u7528<\/div>\n
\u25a0\u00a0EMA\u5c06\u6279\u51c6\u590d\u5b8f\u6c49\u9716\u7684\u66f2\u59a5\u73e0\u5355\u6297<\/div>\n
\u8fd1\u65e5\uff0c\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\uff08EMA\uff09\u4eba\u7528\u533b\u836f\u4ea7\u54c1\u59d4\u5458\u4f1a\u8fd1\u65e5\u53d1\u5e03\u5ba1\u8bc4\u610f\u89c1\uff0c\u5efa\u8bae\u6279\u51c6\u590d\u5b8f\u6c49\u9716\u7814\u53d1\u7684HLX02\uff08\u6ce8\u5c04\u7528\u66f2\u59a5\u73e0\u5355\u6297\uff09\u7684\u4e0a\u5e02\u9500\u552e\u8bb8\u53ef\u7533\u8bf7\u3002\u5982\u83b7\u6279\uff0cHLX02\u5c06\u6210\u4e3a\u8fdb\u5165\u6b27\u6d32\u5e02\u573a\u7684\u9996\u4e2a\u4e2d\u56fd\u4f01\u4e1a\u7814\u53d1\u7684\u5355\u6297\u751f\u7269\u7c7b\u4f3c\u836f\u3002\u8fd1\u671f\u590d\u5b8f\u6c49\u9716\u7684\u53cc\u6297\u521b\u65b0\u7814\u53d1\u4e5f\u8fce\u6765\u4e86\u65b0\u7684\u8fdb\u5c55\uff0c\u591a\u6b3e\u53cc\u6297\u8fdb\u5165\u4e34\u5e8a\u524d\u9636\u6bb5\u3002<\/div>\n
\u00a0<\/div>\n
\u4ea7\u878d\u53d1\u5c55<\/div>\n
\u25a0\u00a0Progenity\u7533\u8bf7IPO\u6b32\u7b79\u96c61\u4ebf\u7f8e\u5143<\/div>\n
\u4e13\u6ce8\u5973\u6027\u5065\u5eb7\u7684\u5206\u5b50\u8bca\u65ad\u5b9e\u9a8c\u5ba4Progenity\u4e8e5\u670829\u65e5\u5411\u7eb3\u65af\u8fbe\u514b\u63d0\u4ea4IPO\u7533\u8bf7\uff0c\u8ba1\u5212\u7b79\u96c61\u4ebf\u7f8e\u5143\u8d44\u91d1\u3002\u5176\u4ea7\u54c1\u7ebf\u5305\u62ec\u9057\u4f20\u75c5\u643a\u5e26\u8005\u68c0\u6d4b\u3001\u65e0\u521b\u4ea7\u524d\u68c0\u6d4b(NIPT)\u548c\u9057\u4f20\u6027\u764c\u75c7\u68c0\u6d4b\u7b49\u3002<\/div>\n
\u25a0\u00a0Twist\u518d\u878d\u8d44\u7ea61\u4ebf\u7f8e\u5143<\/div>\n
\u4e0eSerimmune\u5408\u4f5c\u7814\u53d1\u65b0\u51a0\u6cbb\u7597\u6297\u4f53<\/div>\n
Twist Bioscience\u5ba3\u5e03\u5b8c\u6210\u516c\u5f00\u53d1\u884c\u7ea650\u4e07\u80a1\uff0c\u6263\u9664\u627f\u9500\u6298\u6263\uff0c\u4f63\u91d1\u548c\u53d1\u884c\u8d39\u7528\uff0c\u6240\u5f97\u6b3e\u9879\u51c0\u989d\u7ea6\u4e3a1.074\u4ebf\u7f8e\u5143\u3002<\/div>\n
\u00a0<\/div>\n
\u6b64\u5916\uff0cTwist Bioscience\u548cSerimmune\u5408\u4f5c\u786e\u5b9a\u548c\u8bc4\u4f30\u65b0\u51a0\u80ba\u708e\u6cbb\u7597\u7684\u5019\u9009\u6297\u4f53\u3002\u5728\u7b2c\u4e00\u9636\u6bb5\u786e\u5b9a\u7684\u6297\u539f\u51b3\u5b9a\u7c07\u5c06\u7528\u4e8e\u91cd\u65b0\u7b5b\u9009Twist\u7684\u6587\u5e93\uff0c\u4ee5\u8bc4\u4f30\u65b0\u7684\u5019\u9009\u57fa\u56e0\u3002\u00a0<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u5b89\u6377\u4f26\u5c06\u53d1\u884c5\u4ebf\u7f8e\u5143\u7684\u9ad8\u7ea7\u4f18\u5148\u503a\u5238<\/div>\n
\u5b89\u6377\u4f26\u79d1\u6280\uff08A.US\uff096\u67081\u65e5\u53d1\u5e03\u516c\u544a\u79f0\uff0c\u516c\u53f8\u5c06\u53d1\u884c\u603b\u989d5\u4ebf\u7f8e\u5143\u7684\u9ad8\u7ea7\u4f18\u5148\u503a\u5238\uff0c2030\u5e746\u6708\u5230\u671f\u3002\u6b64\u6b21\u53d1\u884c\u503a\u5238\u7684\u5e74\u5229\u7387\u4e3a2.1%\uff0c\u53d1\u884c\u9884\u8ba1\u5c06\u4e8e2020\u5e746\u67084\u65e5\u7ed3\u675f\u3002\u5b89\u6377\u4f26\u79d1\u6280\u9884\u671f\u6b64\u6b21\u53d1\u884c\u7684\u51c0\u6536\u76ca\u7ea6\u4e3a4.943\u4ebf\u7f8e\u5143\u3002<\/div>\n
\u25a0\u00a0Guardant Health\u5b8c\u6210\u666e\u901a\u80a1\u8f6c\u8ba9<\/div>\n
\u603b\u6536\u76ca11.11\u4ebf\u7f8e\u5143<\/div>\n
Guardant Health\u672c\u5468\u5b8c\u6210\u4e86\u5148\u524d\u5ba3\u5e03\u7684\u666e\u901a\u80a1\u8f6c\u8ba9\u8ba1\u5212\uff0c\u4ee5\u6bcf\u80a184.00\u7f8e\u5143\u7684\u4ef7\u683c\u516c\u5f00\u51fa\u552e\u517613,225,000\u80a1\u666e\u901a\u80a1\uff0c\u5176\u4e2d\uff0c4,312,500\u80a1\uff08\u7ea633%\uff09\u7531Guardant\u8f6c\u8ba9\uff0c\u5269\u4f59\u90e8\u5206\u7531\u8f6f\u94f6\u8f6c\u8ba9\u3002\u6b64\u6b21\u4ea4\u6613JP \u6469\u6839\u662f\u552f\u4e00\u627f\u9500\u5546\u3002<\/div>\n
\u25a0\u00a0FMI \u5b8c\u6210\u6536\u8d2d\u80bf\u7624\u7cbe\u51c6\u533b\u5b66\u516c\u53f8Lexent Bio<\/div>\n
\u5f53\u5730\u65f6\u95f46\u670811\u65e5\uff0c\u7f57\u6c0f\u5b50\u516c\u53f8Foundation Medicine\u5ba3\u5e03\u5df2\u6536\u8d2d\u80bf\u7624\u7cbe\u51c6\u533b\u5b66\u516c\u53f8Lexent Bio\u3002Lexent Bio\u7684\u80bf\u7624\u76d1\u6d4b\u5e73\u53f0\u76ee\u524d\u6b63\u5728\u5f00\u53d1\u4e2d\uff0c\u4e3b\u8981\u662f\u57fa\u4e8e\u4f4e\u901a\u91cf\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u548cDNA\u7532\u57fa\u5316\u5206\u6790\u3002<\/div>\n
\u25a0 \u836f\u4f01OncBioMune\u6536\u8d2dAvant Diagnostics<\/div>\n
\u4e0a\u5468\uff0c\u5236\u836f\u516c\u53f8OncBioMune\u5ba3\u5e03\u5df2\u6536\u8d2d\u4e86\u5206\u5b50\u8bca\u65ad\u516c\u53f8Avant Diagnostics\uff0c\u5e76\u5df2\u5c06\u5176\u66f4\u540d\u4e3aTheralink Technologies\u3002Avant\u7684Theralink\u5206\u6790\u63d0\u4f9b\u4e2a\u6027\u5316\u7684\u533b\u5b66\u6570\u636e\uff0c\u4ee5\u5e2e\u52a9\u533b\u751f\u505a\u51fa\u6709\u5173\u6cbb\u7597\u652f\u6301\u7684\u51b3\u7b56\uff0c\u5e76\u5b9e\u73b0\u57fa\u4e8e\u751f\u7269\u6807\u8bb0\u7269\u7684\u60a3\u8005\u6cbb\u7597\u9009\u62e9\u3002Avant\u8fd8\u5f00\u53d1\u4e86\u78f7\u9178\u86cb\u767d\u8d28\u7ec4\u5b66\u6280\u672f\u6765\u6d4b\u91cf\u6cbb\u7597\u9776\u6807\u548c\u4fe1\u53f7\u901a\u8def\u7684\u6fc0\u6d3b\u72b6\u6001\uff0c\u5e76\u5e94\u7528\u4e8e\u591a\u79cd\u764c\u75c7\u7c7b\u578b\u3002<\/div>\n
\u25a0 \u8d1d\u745e\u57fa\u56e0\u5b8c\u6210\u79c1\u52df\u57fa\u91d1\u7ba1\u7406\u4eba\u5907\u6848<\/div>\n
6\u67088\u65e5\uff0c\u8d1d\u745e\u57fa\u56e0\uff08000710\uff09\u53d1\u5e03\u5173\u4e8e\u4ea7\u4e1a\u6295\u8d44\u7ba1\u7406\u516c\u53f8\u5b8c\u6210\u79c1\u52df\u57fa\u91d1\u7ba1\u7406\u4eba\u5907\u6848\u7684\u516c\u544a\uff0c\u5176\u4ea7\u4e1a\u57fa\u91d1\u7ba1\u7406\u4eba\u4e3a\u798f\u5dde\u745e\u751f\u6295\u8d44\u7ba1\u7406\u6709\u9650\u516c\u53f8\uff0c\u6ce8\u518c\u8d44\u672c1000\u4e07\u5143\uff0c\u5b9e\u7f34\u8d44\u672c305\u4e07\u5143\uff0c\u6ce8\u518c\u8d44\u672c\u5b9e\u7f34\u6bd4\u4f8b30.5%\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u4fe1\u8fbe\u4e0e\u7f57\u6c0f\u96c6\u56e2\u6210\u8fd120\u4ebf\u7f8e\u91d1\u6218\u7565\u5408\u4f5c<\/div>\n
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