\u6587\u7ae0 |\u57fa\u56e0\u6167\u00a0 \u7f16\u8f91 | Dylan<\/div>\n
\u5173\u952e\u8bcd | \u80bf\u7624\u65e9\u7b5b \u7cbe\u51c6\u533b\u7597 \u4e0a\u5e02<\/div>\n\n
\n![\"RmFicvQBAkgCD86sMSlCpeJBzqiao6icJ8tAdTDWzPUSakKH3jFf0xcibe360e1AHdZ5Z08EE2lIvQ7kvibQCE3RRDQ\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCD86sMSlCpeJBzqiao6icJ8tAdTDWzPUSakKH3jFf0xcibe360e1AHdZ5Z08EE2lIvQ7kvibQCE3RRDQ.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\n![\"RmFicvQBAkgCD86sMSlCpeJBzqiao6icJ8t8uC6zylAbl0sSDqDBLyZLT5PKQC7fCgDQiaicKEAvqQ7u6uHhFuWIWXw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCD86sMSlCpeJBzqiao6icJ8t8uC6zylAbl0sSDqDBLyZLT5PKQC7fCgDQiaicKEAvqQ7u6uHhFuWIWXw.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\n![\"RmFicvQBAkgCD86sMSlCpeJBzqiao6icJ8tThut2pWhogsS9CfRsC7PhIF8FArnPia76CSibk4olHGDAICjbiaAVhRibw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCD86sMSlCpeJBzqiao6icJ8tThut2pWhogsS9CfRsC7PhIF8FArnPia76CSibk4olHGDAICjbiaAVhRibw.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u25b3\u56fe\uff1a\u5168\u7403\u764c\u75c7\u7edf\u8ba1\u76f8\u5173\u5b98\u65b9\u6570\u636e<\/div>\n
1\uff092012\u5e74\u7537\u5168\u7403\u6027\u764c\u75c7\u6b7b\u4ea1\u7387\u00a0 2\uff092020\u5e74\u9884\u8ba1\u764c\u75c7\u65b0\u53d1\u548c\u6b7b\u4ea1\u75c5\u4f8b\u6570\u00a0\u00a03\uff091975-2017\u5168\u7403\u764c\u75c7\u53d1\u751f\u548c\u6b7b\u4ea1\u7387<\/div>\n
\uff08\u6765\u6e90\/WHO\uff0cCA\u7b49\uff09<\/div>\n
\u25a0\u00a0\u751f\u547d\u5065\u5eb7\u7684\u521a\u9700<\/div>\n
\u8c08\u5230\u764c\u75c7\u8bca\u7597\uff0c\u9996\u5148\u6211\u4eec\u6765\u770b\u770b\u51e0\u4e2a\u5173\u952e\u6570\u636e\u3002<\/div>\n
\u4eba\u4e00\u751f\u670922%\u7684\u6982\u7387\u7f79\u60a3\u764c\u75c7\uff0c\u8fd9\u662f2018\u5e74\u4e2d\u56fd\u56fd\u5bb6\u764c\u75c7\u767b\u8bb0\u4e2d\u5fc3\u7ed9\u51fa\u7684\u6570\u636e[1]\u3002\u4ece1975-2017\u5e74\u56db\u5341\u4f59\u5e74\u6765\u5168\u7403\u5973\u6027\u7684\u764c\u75c7\u53d1\u75c5\u7387\u6301\u7eed\u4e0a\u5347\uff08\u7537\u6027\u81ea2007\u5e74\u540e\u7565\u6709\u4e0b\u964d\uff09[2]\u3002\u521d\u6b65\u4f30\u7b97\uff0c\u6211\u56fd\u764c\u75c7\u5e73\u5747\u4e94\u5e74\u751f\u5b58\u7387\u53ea\u6709\u7f8e\u56fd\u768455%[3][4][5]\u3002<\/div>\n
\u4ee5\u4e0a\u6570\u636e\u76f8\u5bf9\u5ba2\u89c2\uff0c\u800c\u957f\u4e45\u4ee5\u6765\u88ab\u5ffd\u89c6\uff0c\u8fd1\u51e0\u5e74\u5927\u4f17\u88ab\u4e0d\u65ad\u79d1\u666e\u548c\u6821\u6b63\uff0c\u4e5f\u7ecf\u5e38\u51fa\u73b0\u5728\u80bf\u7624\u7cbe\u51c6\u533b\u7597\u521b\u4e1a\u8def\u6f14\u7684\u524d\u4e09\u9875PPT\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0 \u80bf\u7624\u7cbe\u51c6\u533b\u7597\u4f01\u4e1a\u4e0a\u5e02\u6f6e<\/div>\n
2020\u5e746\u6708\u4e2d\u65ec\uff0c\u5728\u4e2d\u6982\u80a1\u906d\u9047\u4f4e\u8c37\u671f\uff0c\u80bf\u7624\u7cbe\u51c6\u533b\u7597\u8d5b\u9053\u9006\u52bf\u53d1\u5c55\uff0c\u71c3\u77f3\u533b\u5b66(BNR.US)\u548c\u6cdb\u751f\u5b50\uff08GTH.US\uff09\u5728\u4e00\u5468\u5185\u5148\u540e\u767b\u9646\u7f8e\u56fd\u7eb3\u65af\u8fbe\u514b\u4e0a\u5e02\uff0c\u5e02\u503c\u5747\u8fbe\u5230\uff08\u63a5\u8fd1\uff09\u767e\u4ebf\u5143\u7ea7\u3002<\/div>\n
\u540c\u65f6\uff0c\u8fd110\u5bb6\u7c7b\u4f3c\u89c4\u6a21\u7684\u80bf\u7624\u7cbe\u51c6\u533b\u7597\u4f01\u4e1a\u9884\u8ba1\u6b63\u5728\u4e0a\u5e02\u8def\u4e0a\uff0c\u4f8b\u5982\u5317\u4eac\u7684\u5409\u56e0\u52a0\u3001\u81fb\u548c\u79d1\u6280\u3001\u6c42\u81fb\u533b\u5b66\u3001\u5357\u4eac\u7684\u4e16\u548c\u57fa\u56e0\u3001\u4e0a\u6d77\u7684\u9cb2\u8fdc\u57fa\u56e0\u3001\u601d\u8def\u8fea\u3001\u6df1\u5733\u7684\u6d77\u666e\u6d1b\u65af\u7b49\u3002<\/div>\n
\u5728\u6536\u5230\u90e8\u5206PE\u673a\u6784\u5bf9\u6b64\u8d5b\u9053\u7684\u54a8\u8be2\u65f6\uff0c\u7b14\u8005\u4e3e\u51fa\u6587\u7ae0\u5f00\u5934\u7684\u4f8b\u5b50\uff0c\u5373\u52a8\u6001\u7684\u751f\u6001\u5e73\u8861\uff0c\u5305\u62ec\u77ed\u671f\u5185\u8d44\u672c\u4e0e\u521b\u4e1a\u7684\u76f8\u4e92\u4f5c\u7528\u529b\uff0c\u957f\u671f\u57fa\u4e8e\u4ef7\u503c\u7684\u5e02\u573a\u79e9\u5e8f\u56de\u5f52\u3002<\/div>\n
\u672c\u6587\u4ece\u4ea7\u54c1\u672c\u8d28\u51fa\u53d1\uff0c\u5bf9\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u5f00\u653e\u8ba8\u8bba\uff0c\u629b\u7816\u5f15\u7389\uff0c\u6b22\u8fce\u7559\u8a00\u53c2\u4e0e\u3002\u90e8\u5206\u7559\u8a00\u5f97\u5230\u5141\u8bb8\u540e\u53ef\u80fd\u5165\u9009\u57fa\u56e0\u6167\u5373\u5c06\u53d1\u5e03\u7684\u57fa\u56e0\u5927\u6570\u636e<\/a>\u3001\u4e34\u5e8aNGS\u5e94\u7528\u8c03\u7814\u7b49\u884c\u7814\u62a5\u544a\u4e2d\uff08\u6218\u7565\u5408\u4f5c\u8fdb\u884c\u4e2d<\/a>\uff09\u3002<\/div>\n\n
\n![\"RmFicvQBAkgCD86sMSlCpeJBzqiao6icJ8tfI98F5OzSKU4SgjdudlugibicJj96ZRyrJoKu4Cz8QFwPxX9LTyhoomw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCD86sMSlCpeJBzqiao6icJ8tfI98F5OzSKU4SgjdudlugibicJj96ZRyrJoKu4Cz8QFwPxX9LTyhoomw.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u25b3\u56fe\uff1a\u76f8\u5173\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u4e0a\u5e02\u516c\u53f8\u57fa\u672c\u6307\u6807\u7edf\u8ba1<\/div>\n
\uff08\u6765\u6e90\/SEC\uff09<\/div>\n
\u4ece\u8fd0\u8425\u6570\u636e\u4e0a\uff0c\u7efc\u5408\u76ee\u524d\u56fd\u5185\u4e0a\u5e02\u7684\u4e24\u5bb6\u80bf\u7624\u7cbe\u51c6\u533b\u7597\u516c\u53f8\u6765\u770b\uff0c\u81ea2017\u5e74\u8d77\u8425\u6536\u589e\u957f\u5f3a\u52b2\uff08\u590d\u5408\u589e\u957f\u7387\u8d85\u8fc770%\uff09\uff1b\u5728\u5904\u4e8e\u8f83\u5927\u7684\u4e8f\u635f\u72b6\u6001\u4e0b\u83b7\u5f97\u4e8c\u7ea7\u5e02\u573a\u8ba4\u53ef\uff0c\u4f53\u73b0\u8d44\u672c\u5f53\u524d\u5bf9\u7cbe\u51c6\u533b\u7597\u8d5b\u9053\u770b\u591a\uff1b\u8fd9\u540c\u65f6\u5bf9\u7ecf\u8425\u8005\u5f62\u6210\u4e00\u5b9a\u7684\u73b0\u91d1\u6d41\u538b\u529b\u3002<\/div>\n
\u00a0<\/div>\n
\u5bf9\u7167\u5176\u4ed6\u6807\u7684\uff0c\u534e\u5927\u57fa\u56e0\uff08SZ.300676)\u7684\u80bf\u7624\u4e1a\u52a1\u5360\u6bd410%\uff0c2019\u5e74\u7684\u8425\u6536\u4e3a2.83\u4ebf\u5143\uff0c\u540c\u6bd4\u589e\u957f6%\uff1bGuardant Health(NASDAQ.GH)\u53bb\u5e74\u8425\u6536\u4e3a2.14\u4ebf\u7f8e\u5143\uff0c2017-2019\u590d\u5408\u589e\u957f\u7387\u4e3a107%\uff0c\u6bdb\u5229\u7387\u4e3a67%\uff08\u6cdb\u751f\u5b5044%\uff0c\u71c3\u77f3\u533b\u5b6672%\uff09\u3002\u76f8\u8f83\u4e2d\u56fd\u5e02\u573a\u5bb9\u91cf\u548c\u7ade\u4e89\u5ea6\uff0c\u5728\u9500\u552e\u8d39\u7528\u63a7\u5236\u65b9\u9762\u8981\u6c42\u66f4\u9ad8\uff0c\u8fd9\u548c\u4e0b\u6587\u4e1a\u52a1\u6a21\u5f0f\u76f8\u5173\u3002<\/div>\n
\u00a0<\/div>\n
\u76ee\u524d\uff0c\u56fd\u5185\u80bf\u7624\u57fa\u56e0\u68c0\u6d4b\u516c\u53f8\u6838\u5fc3\u4e1a\u52a1\u5305\u62ec\u4f34\u968f\u8bca\u65ad\uff08\u7528\u836f\u6307\u5bfc\uff09\u3001\u65e9\u8bca\u548c\u9884\u540e\u76d1\u6d4b\u3002\u4ece\u6280\u672f\u6210\u719f\u6027\uff08\u5177\u4f53\u53ef\u53c2\u80032020 AACR\u5404\u4f01\u4e1a\u53d1\u8868\u6210\u679c\uff09\u548c\u5e02\u573a\u6559\u80b2\u770b\uff0c\u4e3b\u8981\u96c6\u4e2d\u5728\u4f34\u968f\u8bca\u65ad\uff0c\u7279\u522b\u662f2018-2019\u5e74\uff0cNMPA\u6279\u51c6\u516d\u6b3ePanel\u5230\u672a\u6765\u5927Panel\u7684\u653f\u7b56\u5229\u597d\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0 \u80bf\u7624\u4ea7\u54c1\u62d3\u5c55\u7684\u6f5c\u529b\u548c\u538b\u529b<\/div>\n
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\u00a0<\/div>\n
\u5728\u4ef7\u503c\u53d8\u73b0\u4e0a\uff0c\u53d6\u51b3\u4e8e\u4e0a\u5e02\u901f\u5ea6\u548c\u4e1a\u52a1\u6a21\u5f0f\u3002<\/div>\n
\u9996\u5148\uff0c\u4f34\u968f\u8bca\u65ad\u7684\u68c0\u6d4b\u4ef7\u503c\u53d6\u51b3\u4e8e\u9776\u5411\u836f\u4e0a\u5e02\u901f\u5ea6\u30022019\u5e74\uff0cFDA39\u6b3e\u9776\u5411\u836f\uff08\u5360\u6bd481%\uff09\u3002NMPA\u6279\u51c6\u4e869\u6b3e\u9776\u5411\u836f\uff08\u5360\u6bd418%\uff09\uff0c\u523a\u6fc0\u4e86\u4f34\u968f\u8bca\u65ad\u5e02\u573a\u3002\u5176\u6b21\u53d6\u51b3\u4e8e\u9776\u70b9\u7c7b\u578b\u7684\u5e02\u573a\u8ba4\u53ef\uff0c\u4f8b\u59822019\u5e7411\u6708\uff0cFDA\u6279\u51c6\u7f8e\u56fd\u9996\u4e2a\u9488\u5bf9TMB\u7684\u764c\u75c7\u5168\u5916\u663e\u5b50\u6d4b\u5e8f\u4f53\u5916\u8bca\u65ad\u4ea7\u54c1\uff0c\u5305\u62ec\u76ee\u524d\u5728\u7814\u7684\u7532\u57fa\u5316\u6280\u672f\u6709\u671b\u6210\u4e3a\u4e34\u5e8a\u4f34\u968f\u8bca\u65ad\u6807\u5fd7\u7269\u3002<\/div>\n
\u00a0<\/div>\n
\u57282020\u4e0a\u534a\u5e74\u4e2d\u56fd\u521b\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7\u4e2d\uff0c\u9776\u5411\u836f\u7533\u8bf7\u867d\u6709\u6240\u964d\u4f4e\uff0cPD-1\/L1\u6297\u4f53\u7533\u8bf7\u589e\u591a\u3002\u8fd9\u5bf9\u4e8e\u4f01\u4e1a\u7814\u53d1\u63d0\u51fa\u66f4\u9ad8\u8981\u6c42\uff0c\u4ece\u57fa\u56e0\u7a81\u53d8\u3001TMB\u5230\u514d\u75ab\u7ec6\u80de\u67d3\u8272\u7b49\u3002<\/div>\n
\u5728\u4e1a\u52a1\u6a21\u5f0f\u4e0a\uff0c\u76ee\u524dLDT\u7684\u5f62\u5f0f\uff0c\u56e0\u5408\u89c4\u6027\u9650\u5236\u800c\u5efa\u7acb\u7684\u652f\u4ed8\u6d41\u7a0b\uff0c\u5e26\u6765\u8d28\u63a7\u7684\u4e0d\u53ef\u63a7\uff0c\u4ecd\u9700\u63a2\u7d22\u66f4\u597d\u7684\u65b9\u5f0f\u3002IVD\u8bd5\u5242\u521a\u521a\u8d77\u6b65\uff0c\u80ba\u764c\u7b49\u70ed\u70b9\u764c\u79cd\u7684\u5c0fPanel\u6210\u4e3a\u5404\u5bb6\u89d2\u9010\u62a5\u8bc1\u7684\u5bf9\u8c61\u3002<\/div>\n
\u00a0<\/div>\n
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\u5bf9\u4e8e\u4f34\u968f\u8bca\u65ad\u7684\u7ec8\u7aef\u5e94\u7528\u573a\u666f\u800c\u8a00\uff0c\u6838\u5fc3\u7528\u6237\u662f\u533b\u751f\uff08\u5ba2\u6237\u662f\u60a3\u8005\uff09\u3002\u5728\u5f53\u524d\u654f\u611f\u7684\u533b\u7597\u73af\u5883\u4e0b\u4ee5\u53ca\u5927\u90e8\u5206\u672a\u7eb3\u5165\u533b\u4fdd\u7684\u652f\u4ed8\u6761\u4ef6\u4e0b\uff0c\u9776\u5411\u836f\u7684\u6210\u672c\u63d0\u9ad8\u4e86\u4f34\u968f\u8bca\u65ad\u8fdb\u5165\u4e34\u5e8a\u7684\u95e8\u69db\uff1b\u5316\u7597\u7b49\u66ff\u4ee3\u4ea7\u54c1\u4ecd\u662f\u4e3b\u6d41\u5e02\u573a\uff0c\u8fd9\u9700\u8981\u4e00\u5b9a\u7684\u5e02\u573a\u57f9\u80b2\u65f6\u95f4\u3002<\/div>\n
\u00a0<\/div>\n
\u5728\u6211\u56fd\u52a0\u5927\u521b\u65b0\u836f\u7814\u53d1\u6295\u5165\u548c\u533b\u4fdd\u8986\u76d6\u529b\u5ea6\u4e0a\uff0c\u8f83\u4e3a\u4e50\u89c2\uff0c\u57fa\u672c\u76d8\u4ecd\u5728\u4e8e\u7ecf\u6d4e\u603b\u91cf\u7684\u652f\u51fa\u3002\u800c\u56fd\u4ea7\u6d4b\u5e8f\u4eea\u3001\u8bd5\u5242\u76d2\u7b49\u4e1a\u6001\u7684\u5f62\u6210\uff0c\u5bf9\u964d\u4f4e\u4f34\u968f\u8bca\u65ad\u4ea7\u54c1\u81ea\u8eab\u7684\u6210\u672c\u6709\u8f83\u5927\u7684\u63a8\u52a8\u4f5c\u7528\u3002<\/div>\n\n
\n![\"RmFicvQBAkgD9senKyZv1wVLTCY6YDUs4XKzaTOQ1vljSeYfRWiaRvdo4DYWPvtotwttkq2XJ1OAu336kjobuxFA\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgD9senKyZv1wVLTCY6YDUs4XKzaTOQ1vljSeYfRWiaRvdo4DYWPvtotwttkq2XJ1OAu336kjobuxFA.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u25a0 \u53ef\u671f\u5f85\u7684\u7206\u6b3e\uff0c\u5bf9\u5e94\u7684\u6301\u4e45\u6218<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
\u9ad8\u51c0\u503c\u4eba\u7fa4\u5bf9\u764c\u75c7\u9884\u8b66\u9884\u9632\u7684\u521a\u9700\uff0c\u4ee5\u53ca\u75ab\u60c5\u4e0b\u63d0\u5347\u666e\u901a\u5927\u4f17\u5bf9\u751f\u547d\u5065\u5eb7\u7684\u91cd\u89c6\uff0c\u5fc5\u5c06\u5e26\u676510-100\u500d\u7684\u80bf\u7624\u7cbe\u51c6\u533b\u7597\uff08\u65e9\u8bca\u3001\u7528\u836f\u3001\u9884\u540e\u7b49\uff09\u7684\u5e02\u573a\u89c4\u6a21\u3002\u5173\u952e\u662f\u65f6\u95f4\u5468\u671f\uff0c\u5bf9\u7814\u53d1\u8005\u548c\u521b\u4e1a\u8005\u7684\u8010\u5fc3\u548c\u6301\u4e45\u6218\u5907\u8d44\u6e90\u6709\u975e\u5e38\u5f3a\u7684\u8003\u9a8c\uff0c\u53ef\u80fd\u662f2\u5e74\u30015\u5e74\u751a\u81f3\u66f4\u957f\u65f6\u95f4\uff0c<\/div>\n
\u00a0<\/div>\n
\u53c2\u8003\u8d44\u6599\uff1a<\/div>\n
1. Jie He et al., Cancer incidence and mortality in China, 2014\uff0cChin J Cancer Res(2018)<\/div>\n
2.\u00a0Rebecca L. Siegel MPH et al., Cancer statistics, CA(2020)<\/div>\n
3.\u00a0https:\/\/ourworldindata.org\/cancer-death-rates-are-falling-five-year-survival-rates-are-rising<\/div>\n
4.\u00a0Jie He et al.,\u00a0Cancer statistics in China, 2015, CA(2016)<\/div>\n
5.\u00a0https:\/\/seer.cancer.gov\/explorer\/application.html<\/div>\n
6. BNR\uff1ahttps:\/\/www.sec.gov\/Archives\/edgar\/data\/1792267\/000119312520167229\/d806768d424b4.htm<\/div>\n
7. GTH\uff1ahttps:\/\/www.sec.gov\/Archives\/edgar\/data\/1782594\/000119312520174757\/d779078d424b4.htm<\/div>\n
8. \u6c49\u9753\u7684\u533b\u836f\u79d1\u6280\u524d\u6cbf\uff1a\u71c3\u77f3\u533b\u5b66\u7684\u62db\u80a1\u4e66\u89e3\u8bfb&\u4e2a\u4eba\u601d\u8003\uff08\u5185\u542b\u548cGuardant\u7684\u6bd4\u8f83\uff09<\/div>\n
9.\u00a02019\u5e74FDA\u548cNMPA\u6279\u51c6\u7684\u65b0\u578b\u9776\u5411\u836f\u7269<\/div>\n
10.\u00a02020\u4e0a\u534a\u5e74\u4e2d\u56fd\u521b\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7<\/div>\n
\u00a0<\/div>\n
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\u6218\u7565\u5408\u4f5c\u8fdb\u884c\u4e2d<\/div>\n
\u25bd<\/div>\n\n
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<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u6269\u5c55\u9605\u8bfb<\/div>\n
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\u00a0<\/div>\n
\u00a0\u5173\u4e8e\u57fa\u56e0\u6167\u00a0<\/div>\n
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