{"id":9065,"date":"2020-07-26T23:36:58","date_gmt":"2020-07-26T15:36:58","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100015152&idx=1&sn=e4fb8591a4a57adca7749e4a8e4aeda9&chksm=6b714e875c06c79174a13a936823b333bfea84570b0668891aba2358a1fc9285f25c8599b972#rd"},"modified":"2026-04-02T09:39:51","modified_gmt":"2026-04-02T01:39:51","slug":"975150","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2020\/07\/26\/975150\/","title":{"rendered":"\u5468\u62a5\u4e28\u5bab\u9888\u764c\u7b5b\u67e5\u6269\u5927\u81f314\u79cd\u57fa\u56e0\u5206\u578b\uff0c\u4e9a\u6d32\u9996\u6b21\u57fa\u56e0\u7f16\u8f91\u6cbb\u7597\u5730\u8d2b"},"content":{"rendered":"

<\/p>\n

GeneMail \u5468\u62a5<\/div>\n
No.106<\/div>\n
\u7f16\u8f91| \u7f57\u6e58\u00a0\u6587\u7ae0\u00a0|\u00a0\u57fa\u56e0\u6167<\/div>\n
\u00a0<\/div>\n
\u5934\u6761<\/div>\n
\u25a0\u00a0\u5973\u6027\u798f\u97f3<\/div>\n
BD\u6269\u5c55\u81f314\u79cd\u57fa\u56e0\u5206\u578b\u7684HPV\u68c0\u6d4b\u4ea7\u54c1\u83b7\u6279<\/div>\n\n
\n
\"RmFicvQBAkgBeJzO8pcrncOauoTGZlJ48icSYIq2dT1djKM7CFEftZrlNpgmZvxUmuuUVfJ9Sbuxlk0wkvwD8Isg\"\/<\/figure><\/div>\n\n
BD Onclarity\u2122HPV\u6d4b\u5b9a3\u5b54PCR\u8bd5\u5242\u5b54<\/div>\n
\u56fe\/https:\/\/www.bd.com\/en-us<\/div>\n
\u65e5\u524d\uff0cFDA \u6279\u51c6\u4e86BD Onclarity HPV Assay\u7684\u6269\u5c55\u7248\u672cPMA\uff08\u4e0a\u5e02\u524d\u6279\u51c6\uff09\uff0c\u6b64\u4ea7\u54c1\u53ef\u5728\u4e00\u6b21\u5206\u6790\u4e2d\u68c0\u6d4b\u548c\u9274\u5b9a14\u79cd\u9ad8\u98ce\u9669HPV\u7c7b\u578b\uff0831\u300151\u300152\u300133 \/ 58\u300135 \/ 39\/68\u548c56\/59\/66\u4ee5\u53ca\u6807\u51c616,18\u548c45\uff09\uff0c\u5e76\u63d0\u4f9b\u57fa\u56e0\u5206\u578b\u4fe1\u606f\uff0c\u6709\u52a9\u60a3\u8005\u505a\u597d\u98ce\u9669\u5206\u5c42\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.accessdata.fda.gov\/scripts\/cdrh\/cfdocs\/cfpma\/pma.cfm?id=P160037S004<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u4e9a\u6d32\u9996\u6b21\u901a\u8fc7\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u6cbb\u7597\u5730\u8d2b<\/div>\n
\u8fd1\u65e5\uff0c\u4e24\u4f4d\u91cd\u75c7\u5730\u8d2b\u60a3\u513f\u5728\u4e2d\u5357\u5927\u5b66\u6e58\u96c5\u533b\u9662\u8fce\u6765\u4e86\u201c\u65b0\u751f\u201d\uff0c\u4ed6\u4eec\u4e0d\u662f\u901a\u8fc7\u4f20\u7edf\u7684\u9aa8\u9ad3\u79fb\u690d\u6cbb\u6108\uff0c\u800c\u662f\u53c2\u4e0e\u4e86\u201c\u7ecf\u03b3\u73e0\u86cb\u767d\u91cd\u6fc0\u6d3b\u7684\u81ea\u4f53\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u6cbb\u7597\u91cd\u578b\u03b2\u5730\u4e2d\u6d77\u8d2b\u8840\u5b89\u5168\u6027\u53ca\u6709\u6548\u6027\u7684\u4e34\u5e8a\u7814\u7a76\u201d\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/div>\n
\u8fd9\u662f\u4e0a\u6d77\u90a6\u8000\u751f\u7269\u4e0e\u4e2d\u5357\u5927\u5b66\u6e58\u96c5\u533b\u9662\u5408\u4f5c\u5f00\u5c55\u7684\u91cd\u5ea6\u5730\u8d2b\u4e34\u5e8a\u7814\u7a76\uff0c\u662f\u4e9a\u6d32\u9996\u6b21\u901a\u8fc7\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u6cbb\u7597\u5730\u8d2b\uff0c\u4e5f\u662f\u5168\u4e16\u754c\u9996\u6b21\u6210\u529f\u901a\u8fc7CRISPR\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u6cbb\u7597\u03b20\/\u03b20\u578b\u91cd\u5ea6\u5730\u8d2b\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5\u201c\u4eae\u5251\u201d\uff0c\u91cd\u75c7\u5730\u8d2b\u60a3\u8005\u53ef\u4ee5\u4e0d\u518d\u82e6\u7b49\u914d\u578b\uff1f<\/a><\/div>\n
\u00a0<\/div>\n
\u25bd<\/div>\n
\u00a0\u300a\u4e2d\u56fd\u4e34\u5e8aNGS\u5e94\u7528\u9700\u6c42\u8c03\u7814\u62a5\u544a\u300b<\/a><\/div>\n
\u8bda\u9080\u51a0\u540d\u5408\u4f5c<\/div>\n\n
\n
\"RmFicvQBAkgBeJzO8pcrncOauoTGZlJ48WuS0gjxiaZPQpuZB2MJJic85koSqrn6afEktHqvXticbz2PZmR4pfuQlw\"\/<\/figure><\/div>\n\n<\/div>\n
<\/div>\n
<\/div>\n
\u25a0 \u62dc\u8033\u53d1\u8d77\u57fa\u56e0\u6cbb\u7597\u4f01\u4e1a\u8fd12\u4ebf\u5143A\u8f6e\u6295\u8d44<\/div>\n
7\u670822\u65e5\uff0c\u62dc\u8033\uff08Leaps by Bayer\uff09\u548c\u6668\u5174\u8d44\u672c\uff08Morningside Ventures\uff09\u7275\u5934\u53d1\u8d77\u751f\u7269\u6280\u672f\u516c\u53f8Vesigen Therapeutics\u7684A\u8f6e\u6295\u8d44\uff0c\u91d1\u989d\u7ea62850\u4e07\u7f8e\u5143\u3002Vesigen Therapeutics\u6b63\u5728\u5f00\u53d1\u4e00\u79cd\u7279\u6b8a\u7c7b\u578b\u7684\u7ec6\u80de\u5916\u56ca\u6ce1ARMMS\uff08\u4f7f\u7528ARRDC1\u4ecb\u5bfc\u7684\u5fae\u56ca\u6ce1\uff09\u52a9\u529b\u751f\u7269\u836f\u7269\u8f93\u9001\u3002<\/div>\n
\u25a0\u00a0\u5355\u78b1\u57fa\u7f16\u8f91\u65b0\u5de5\u5177\u53ef\u5b9e\u73b0C-G\u53caC-A\u78b1\u57fa\u98a0\u6362<\/div>\n
\n\n
\n
\"RmFicvQBAkgBeJzO8pcrncOauoTGZlJ48PrxPAUfyPiaEst7rZEEIeUq0icgbp3fmBQOgia5NPbl4hQDcy0O6ibY0Mw\"\/<\/figure><\/div>\n\n
\u80de\u5627\u5576\uff08C\uff09\u8131\u6c28\u57fa\u7a81\u53d8\u540e\u7684\u4fee\u590d\u60c5\u51b5\u793a\u610f\u56fe<\/div>\n
\u56fe\u6e90\uff1adoi.org\/10.1038\/s41587-020-0592-2<\/div>\n
7\u670820\u65e5\uff0c\u00a0Nature Biotechnology\u00a0\u520a\u6587\u663e\u793a\u901a\u8fc7\u6539\u9020\u73b0\u6709\u7684\u5355\u78b1\u57fa\u7f16\u8f91\u5de5\u5177CBE\uff0c\u6784\u5efa\u51fa\u54fa\u4e73\u52a8\u7269\u7ec6\u80de\u9002\u7528\u7684\u4ecb\u5bfcC-G\u78b1\u57fa\u98a0\u6362\u7684\u65b0\u5de5\u5177GBE\/CGBE\uff0c\u8ba9\u5355\u78b1\u57fa\u7f16\u8f91\u8fdb\u5165\u65b0\u9636\u6bb5\u3002<\/div>\n
\u53c2\u8003\u6587\u732e>><\/div>\n
https:\/\/doi.org\/10.1038\/s41587-020-0592-2<\/div>\n
\u00a0<\/div>\n
\u91cd\u5927\u653f\u7b56<\/div>\n
\u25a0 \u6df1\u5316\u533b\u836f\u536b\u751f\u4f53\u5236\u6539\u9769<\/div>\n
2020\u5e74\u4e0b\u534a\u5e74\u91cd\u70b9\u5de5\u4f5c\u4efb\u52a1<\/div>\n
7\u670823\u65e5\uff0c\u56fd\u52a1\u9662\u529e\u516c\u5385\u5370\u53d1\u300a\u6df1\u5316\u533b\u836f\u536b\u751f\u4f53\u5236\u6539\u97692020\u5e74\u4e0b\u534a\u5e74\u91cd\u70b9\u5de5\u4f5c\u4efb\u52a1\u300b\uff0c\u5305\u62ec\uff1a\u52a0\u5f3a\u516c\u5171\u536b\u751f\u4f53\u7cfb\u5efa\u8bbe\uff0c\u6df1\u5165\u5b9e\u65bd\u5065\u5eb7\u4e2d\u56fd\u884c\u52a8\uff0c\u6df1\u5316\u516c\u7acb\u533b\u9662\u7efc\u5408\u6539\u9769\uff0c\u6df1\u5316\u533b\u7597\u4fdd\u969c\u5236\u5ea6\u6539\u9769\u548c\u5065\u5168\u836f\u54c1\u4f9b\u5e94\u4fdd\u969c\u4f53\u7cfb\u7b49\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.gov.cn\/zhengce\/content\/2020-07\/23\/content_5529417.htm<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u9996\u4e2a\u80ba\u5e72\u7ec6\u80de\u4ea7\u54c1IND\u83b7\u6279<\/div>\n
7\u670815\u65e5\uff0c\u56fd\u5bb6\u836f\u76d1\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\u5b98\u7f51\u663e\u793a\uff0c\u6c5f\u897f\u4ed9\u8377\u533b\u5b66\u65d7\u4e0b\u7684REGEND001\u7ec6\u80de\u81ea\u4f53\u56de\u8f93\u5236\u5242\u83b7\u4e34\u5e8a\u8bd5\u9a8c\u6279\u51c6\uff0c\u7528\u4e8e\u6cbb\u7597\u65e9\u3001\u4e2d\u671f\u7279\u53d1\u6027\u80ba\u7ea4\u7ef4\u5316\uff0c\u8fd9\u6b3e\u5e72\u7ec6\u80de\u65b0\u836f\u662f\u6211\u56fd\u9996\u4e2a\u83b7\u6279\u8fdb\u5165\u4e34\u5e8a\u5b9e\u9a8c\u7684\u80ba\u5e72\u7ec6\u80de\u4ea7\u54c1\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u534e\u5927\u5b50\u516c\u53f8\u88ab\u7f8e\u56fd\u5217\u5165\u5b9e\u4f53\u6e05\u5355<\/div>\n
7\u670820\u65e5\uff0c\u7f8e\u56fd\u5546\u52a1\u90e8\u4ea7\u4e1a\u5b89\u5168\u5c40\uff08BIS\uff09\u4ee5\u65b0\u7586\u4eba\u6743\u95ee\u9898\u4e3a\u7531\u5c0611\u4e2a\u4e2d\u56fd\u5b9e\u4f53\u52a0\u5165\u5b9e\u4f53\u6e05\u5355\uff0c\u5305\u62ec\u534e\u5927\u5b50\u516c\u53f8Beijing Liuhe BGI\uff08\u5317\u4eac\u516d\u5408\u534e\u5927\u57fa\u56e0\uff09\u3001Xinjiang Silk Road BGI\uff08\u65b0\u7586\u4e1d\u8def\u534e\u5927\u57fa\u56e0\uff09\u3002\u8fd9\u662fBIS\u7b2c\u4e09\u6b21\u4ee5\u76f8\u4f3c\u7406\u7531\u5c06\u4e2d\u56fd\u5b9e\u4f53\u52a0\u5165\u5b9e\u4f53\u6e05\u5355\u3002<\/div>\n
\u25bd<\/div>\n
\u00a0\u300a\u57fa\u56e0\u5927\u6570\u636e\u667a\u80fd\u751f\u4ea7\u53ca\u5206\u6790\u300b\u884c\u7814\u62a5\u544a\u00a0<\/a>\u00a0<\/div>\n
\u8bda\u9080\u51a0\u540d\u5408\u4f5c<\/div>\n\n
\n
\"RmFicvQBAkgA4O16BdkL0YibgTicdwho6GumQtSiaD7cPH6KiajGwUrvxK90QbvR7Ug9NaC3NpCpB8Jay7LEThia0FBQ\"\/<\/figure><\/div>\n\n
\n
\"RmFicvQBAkgA4O16BdkL0YibgTicdwho6Gud4dHUYSwyZKdt7U0GbVCVQIjfdAX4mqVO9dChwAYkJ6j0bibakU44SA\"\/<\/figure><\/div>\n\n
\n
\"RmFicvQBAkgA4O16BdkL0YibgTicdwho6GuAR0AribuNHjwxMtevvt2kqFl3icVjJz96fibk47Ev2mEvBQnKeCIhEgaw\"\/<\/figure><\/div>\n\n
\n
\"RmFicvQBAkgA4O16BdkL0YibgTicdwho6Gubjh8VyXlqM3YNicrtaeQGyMmq5LvxM0QTslwj46P4WAVHBYrc6rbWOw\"\/<\/figure><\/div>\n\n
\u25a0\u00a0CDE\u5f81\u6c42\u6297\u80bf\u7624\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u76f8\u5173\u610f\u89c1<\/div>\n
\u4e3a\u9f13\u52b1\u521b\u65b0\uff0c7\u670817\u65e5\uff0cCDE\u53d1\u5e03\u4e86\u300a\u6297\u80bf\u7624\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7edf\u8ba1\u5b66\u8bbe\u8ba1\u6307\u5bfc\u539f\u5219\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b\uff0c\u5185\u5bb9\u5305\u62ec\u7597\u6548\u7ec8\u70b9\u3001\u63a2\u7d22\u6027\u8bd5\u9a8c\u548c\u786e\u8bc1\u6027\u8bd5\u9a8c\u7b49\u3002\u4ee5\u671f\u4fc3\u8fdb\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u5404\u76f8\u5173\u65b9\u5bf9\u6297\u80bf\u7624\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7edf\u8ba1\u5b66\u8bbe\u8ba1\u7684\u7406\u89e3\u4e0e\u5408\u7406\u5e94\u7528\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.cde.org.cn\/attachmentout.do?mothed=list&id=092c069979c86ea9<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u52a8\u6001<\/div>\n
\u25a0\u00a0\u56fd\u5bb6\u4e2d\u5c0f\u4f01\u4e1a\u53d1\u5c55\u57fa\u91d1\u6210\u7acb<\/div>\n
6\u670822\u65e5\uff0c\u56fd\u5bb6\u4e2d\u5c0f\u4f01\u4e1a\u53d1\u5c55\u57fa\u91d1\uff08\u56fd\u5bb6\u4e2d\u5c0f\u4f01\u4e1a\u53d1\u5c55\u57fa\u91d1\u6709\u9650\u516c\u53f8\uff09\u6b63\u5f0f\u6ce8\u518c\u6210\u7acb\u3002\u6ce8\u518c\u8d44\u672c\u4e3a357.5\u4ebf\u5143\u4eba\u6c11\u5e01\uff0c\u7ecf\u8425\u8303\u56f4\u4e3a\u4e00\u822c\u9879\u76ee\uff1a\u80a1\u6743\u6295\u8d44\uff0c\u6295\u8d44\u7ba1\u7406\uff0c\u6295\u8d44\u54a8\u8be2\uff0c\u6cd5\u5b9a\u4ee3\u8868\u4eba\u3001\u8463\u4e8b\u957f\u4e3a\u524d\u5de5\u4e1a\u548c\u4fe1\u606f\u5316\u90e8\u4e2d\u5c0f\u4f01\u4e1a\u5c40\u5c40\u957f\u9a6c\u5411\u6656\u3002\u80a1\u4e1c\u5305\u62ec\u56fd\u5bb6\u8d22\u653f\u90e8\u3001\u4e2d\u56fd\u70df\u8349\u3001\u4e2d\u56fd\u4eba\u5bff\u3001\u4e0a\u6d77\u56fd\u76db\u96c6\u56e2\u3001\u6d66\u4e1c\u79d1\u521b\u96c6\u56e2\u7b49\uff0c\u5176\u4e2d\uff0c\u8d22\u653f\u90e8\u4e3a\u7b2c\u4e00\u5927\u80a1\u4e1c\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0 \u9646\u9053\u57f9B\u8f6e\u878d\u8d44\u8d855\u4ebf\u5143<\/div>\n
\u8fd1\u65e5\uff0c\u5168\u56fd\u8457\u540d\u8840\u6db2\u75c5\u4e13\u79d1\u533b\u7597\u96c6\u56e2\u9646\u9053\u57f9\u533b\u7597\u5b8c\u6210\u8d85\u8fc75\u4ebf\u5143B\u8f6e\u80a1\u6743\u878d\u8d44\uff0c\u672c\u8f6e\u878d\u8d44\u7531\u65b0\u52a0\u5761\u4e3b\u6743\u57fa\u91d1\u6de1\u9a6c\u9521\u9886\u6295\uff0cInvestcorp\u8ddf\u6295\u3002\u6d69\u60a6\u8d44\u672c\u5728\u672c\u6b21\u4ea4\u6613\u4e2d\u62c5\u4efb\u72ec\u5bb6\u8d22\u52a1\u987e\u95ee\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0 \u80bf\u7624\u68c0\u6d4b\u201c\u5927Panel654\u201d\u4e0a\u5e02<\/div>\n
7\u670823\u65e5\uff0c\u8d1d\u745e\u57fa\u56e0\u53c2\u80a1\u7684\u548c\u745e\u57fa\u56e0\u201c\u5927Panel654\u201d\u5b9e\u4f53\u7624\u5168\u9776\u70b9\u57fa\u56e0\u68c0\u6d4b\u8bd5\u5242\u76d2\u4e0a\u5e02\uff0c\u5c06\u8d1d\u745e\u7684\u4e1a\u52a1\u62d3\u5c55\u5230\u4e86\u6700\u524d\u6cbf\u7684\u80bf\u7624\u68c0\u6d4b\u9886\u57df\uff0c\u8d1d\u745e\u57fa\u56e0\u80a1\u4ef7\u903c\u8fd1\u5386\u53f2\u6700\u9ad8\u4f4d\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0Thermo Fisher\u63d0\u9ad8\u6536\u8d2dQIAGEN\u7684\u4ef7\u683c<\/div>\n
7\u670816\u65e5\uff0cThermo Fisher Scientific\u548cQIAGEN\u8868\u793a\uff0c\u5df2\u4fee\u6539\u6536\u8d2d\u534f\u8bae\u7684\u6761\u6b3e\uff0c\u5c06QIAGEN\u80a1\u7968\u7684\u62a5\u4ef7\u63d0\u9ad8\u5230\u6bcf\u80a143\u6b27\u5143\uff0c\u4ee5\u201c\u53cd\u6620\u4e1a\u52a1\u7684\u516c\u5141\u4ef7\u503c\u201d\u3002<\/div>\n
\u00a0<\/div>\n
\u79d1\u7814\u6210\u679c<\/div>\n
\u25a0\u00a0\u9f3b\u54bd\u764c\u5355\u7ec6\u80de\u56fe\u8c31\u9996\u6b21\u88ab\u6784\u5efa<\/div>\n
7\u670820\u65e5\uff0c\u4e2d\u5c71\u5927\u5b66\u3001\u534e\u5927\u3001\u4e2d\u56fd\u79d1\u5b66\u9662\u6df1\u5733\u5148\u8fdb\u6280\u672f\u7814\u7a76\u9662\u7b49\u591a\u5355\u4f4d\u5408\u4f5c\u5b8c\u6210\u7684\u6700\u65b0\u7814\u7a76\u6210\u679c\u53d1\u8868\u5728Cell Research\u3002\u8fd9\u9879\u7814\u7a76\u5bf9\u9f3b\u54bd\u764c\u80bf\u7624\u7ec6\u80de\u7684\u5f02\u8d28\u6027\u548c\u514d\u75ab\u7ec6\u80de\u7684\u591a\u6837\u6027\u8fdb\u884c\u4e86\u6df1\u5165\u5206\u6790\uff0c\u9274\u5b9a\u4e86\u4e00\u7cfb\u5217\u4e0e\u60a3\u8005\u9884\u540e\u5bc6\u5207\u76f8\u5173\u7684\u5206\u5b50\u7279\u5f81\u53ca\u6f5c\u5728\u7684\u6cbb\u7597\u9776\u70b9\u3002\u7814\u7a76\u9996\u6b21\u6784\u5efa\u4e86\u5168\u9762\u7684\u9f3b\u54bd\u764c\u5355\u7ec6\u80de\u56fe\u8c31\uff0c\u5e76\u642d\u5efa\u4e86\u4eba\u7c7b\u9f3b\u54bd\u764c\u84dd\u56fe\u5206\u6790\u7f51\u7ad9\u3002<\/div>\n
\u53c2\u8003\u6587\u732e>>https:\/\/www.nature.com\/articles\/s41422-020-0374-x<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u65b0\u57fa\u56e0\u7f16\u8f91\u5de5\u5177\u53d1\u73b0\uff0c\u9776\u5411\u66f4\u5e7f\u6cdb<\/div>\n
7\u670816\u65e5\uff0c\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u56e2\u961f\u53d1\u73b0\u4e00\u79cd\u8d85\u7d27\u51d1\u7684CRISPR\u9176\uff08\u4ec5\u89c1\u4e8e\u5de8\u5927\u7684\u566c\u83cc\u4f53\u4e2d\uff09\uff0c\u88ab\u547d\u540d\u4e3aCRISPR- Cas\u03a6\uff0c\u4e0eCas9\u548cCas12\u76f8\u6bd4\uff0c\u5b83\u80fd\u5bf9\u66f4\u5e7f\u6cdb\u7684\u57fa\u56e0\u5e8f\u5217\u8bbe\u9776\u3002\u7814\u7a76\u8bc1\u660e\uff0cCas\u03a6\u80fd\u6210\u529f\u5730\u7f16\u8f91\u4eba\u7c7b\u548c\u690d\u7269\u57fa\u56e0\u7ec4\u3002<\/div>\n
\u53c2\u8003\u6587\u732e>>https:\/\/science.sciencemag.org\/content\/369\/6501\/333<\/div>\n
\u00a0<\/div>\n
\u25a0 ctDNA\u7532\u57fa\u5316\u6cdb\u764c\u7b5b\u67e5\u6bd4\u5e38\u89c4\u8bca\u65ad<\/div>\n
\u63d0\u524d4\u5e74\u53d1\u73b0\u764c\u75c7<\/div>\n
7\u670821\u65e5\uff0c\u590d\u65e6\u5927\u5b66\u4e0e\u9e4d\u8fdc\u57fa\u56e0\u7814\u7a76\u56e2\u961f\u5728Nature Communication\u53d1\u8868\u6700\u65b0\u7814\u7a76\u6210\u679c\u663e\u793a\uff1a\u8840\u6db2\u65e0\u521b\u68c0\u6d4b\u53ef\u4ee5\u6bd4\u5e38\u89c4\u8bca\u65ad\u63d0\u524d\u56db\u5e74\u53d1\u73b0\u764c\u75c7\u3002\u7814\u7a76\u4eba\u5458\u5229\u7528ctDNA\u7532\u57fa\u5316\u6cdb\u764c\u7b5b\u67e5\u6280\u672fPanSeer\u65b9\u6cd5\uff0c\u5b9e\u73b0\u6bd4\u4e34\u5e8a\u8bca\u65ad\u63d0\u524d4\u5e74\u53d1\u73b0\u8840\u6db2\u4e2d\u7684\u5fae\u91cf\u80bf\u7624\u7532\u57fa\u5316\u4fe1\u53f7\u3002<\/div>\n
\u53c2\u8003\u6587\u732e>>https:\/\/www.nature.com\/articles\/s41467-020-17316-z<\/div>\n
\u00a0<\/div>\n
\u25a0 \u5927\u8111\u7a81\u89e6\u56fe\u8c31\u8bde\u751f<\/div>\n
\u8fd1\u65e5\uff0c\u56fd\u5916\u7684\u79d1\u5b66\u5bb6\u4eec\u4ee5\u5355\u7a81\u89e6\u7684\u5206\u8fa8\u7387\uff0c\u5206\u6790\u4e86\u5c0f\u9f20\u5927\u8111\u768450\u4ebf\u4e2a\u201c\u5174\u594b\u6027\u7a81\u89e6\u201d\u7684\u5206\u5b50\u4e0e\u5f62\u6001\u7279\u5f81\u3002\u7814\u7a76\u4eba\u5458\u4eec\u6307\u51fa\uff0c\u8fd9\u9879\u5bf9\u4e8e\u7a81\u89e6\u7684\u201c\u4eba\u53e3\u666e\u67e5\u201d\uff0c\u6709\u52a9\u4e8e\u8ba9\u6211\u4eec\u5728\u5927\u8111\u53d1\u80b2\u7684\u4e0d\u540c\u65f6\u95f4\u4e0e\u5730\u70b9\uff0c\u7814\u7a76\u7a81\u89e6\u7684\u53d8\u5316\uff0c\u4ee5\u53ca\u76f8\u5e94\u7684\u884c\u4e3a\u6539\u53d8\u3002<\/div>\n
\u53c2\u8003\u6587\u732e>>https:\/\/science.sciencemag.org\/content\/369\/6501\/270<\/div>\n
\u00a0<\/div>\n
\u25a0 piRNA\u662f\u6307\u5bfcDNA\u4ece\u5934\u7532\u57fa\u5316\u7684\u91cd\u8981\u6267\u884c\u8005<\/div>\n
\u8fd1\u65e5\uff0c\u82f1\u56fd\u7231\u4e01\u5821\u5927\u5b66\u7814\u7a76\u56e2\u961f\u53d1\u73b0\uff0cSPOCD1\u662fpiRNA\u6307\u5bfcDNA\u4ece\u5934\u7532\u57fa\u5316\u7684\u91cd\u8981\u6267\u884c\u8005\u3002\u7814\u7a76\u4eba\u5458\u63d0\u51fa\u4e00\u4e2a\u6a21\u578b\uff0c\u501f\u6b64\u5c06MIWI2\u675f\u7f1a\u5230\u65b0\u751f\u7684TE\u8f6c\u5f55\u672c\u4e0a\uff0c\u901a\u8fc7SPOCD1\u52df\u96c6\u4e86\u6291\u5236\u6027\u67d3\u8272\u8d28\u91cd\u5851\u6d3b\u52a8\u548c\u4ece\u5934\u7532\u57fa\u5316\u88c5\u7f6e\uff0c\u6700\u540e\u786e\u5b9a\u4e86\u54fa\u4e73\u52a8\u7269piRNA\u662f\u6307\u5bfcDNA\u7532\u57fa\u5316\u7684\u4e00\u79cd\u65b0\u9896\u4e14\u5fc5\u4e0d\u53ef\u5c11\u7684\u6267\u884c\u8005\u3002<\/div>\n
\u53c2\u8003\u6587\u732e>>https : \/\/www.nature.com\/articles\/s41586-020-2557-5<\/div>\n
\u00a0<\/div>\n
\u6218\u75ab\u4e4b\u58f0<\/div>\n
\u25a0\u00a0\u672a\u611f\u67d3\u4eba\u7fa4\u68c0\u51fa\u65b0\u51a0\u7279\u5f02\u6027\u514d\u75abT\u7ec6\u80de<\/div>\n
7\u670815\u65e5\uff0c\u56fd\u5916\u7814\u7a76\u56e2\u961f\u5728Nature\u4e0a\u53d1\u8868COVID-19\u6700\u65b0\u7814\u7a76\u6210\u679c\uff0c\u63ed\u793a\u4e86\u5728\u672a\u611f\u67d3\u4eba\u7fa4\u4e2d\u4e5f\u80fd\u68c0\u6d4b\u5230\u65b0\u51a0\u75c5\u6bd2\u7279\u5f02\u6027T\u7ec6\u80de\uff0c\u800c\u4e14SARS\u5eb7\u590d\u60a3\u8005\u4e2d\u7684\u7279\u5f02T\u7ec6\u80de\u4e0e\u65b0\u51a0\u75c5\u6bd2\u5177\u6709\u5f3a\u5927\u4ea4\u53c9\u53cd\u5e94\u6027\u3002\u8fd9\u8868\u660e\uff0c\u03b2\u51a0\u72b6\u75c5\u6bd2\u611f\u67d3\u53ef\u8bf1\u5bfc\u4eba\u4f53\u4ea7\u751f\u5bf9\u7ed3\u6784\u86cb\u767dNP\u7684\u591a\u7279\u5f02\u6027\u548c\u6301\u4e45\u7684T\u7ec6\u80de\u514d\u75ab\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u65b0\u51a0\u75ab\u82d7\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u5c55<\/div>\n
7\u670820\u65e5\uff0c\u300a\u67f3\u53f6\u5200\u300b\u4e0a\u520a\u8f7d\u4e86\u4e24\u6b3e\u65b0\u51a0\u75c5\u6bd2\u75ab\u82d7\uff08COVID-19\uff091\u671f\/2\u671f\u4e34\u5e8a\u8bd5\u9a8c\u7684\u6700\u65b0\u7ed3\u679c\uff0c\u5176\u4e2d\u4e00\u6b3e\u9648\u8587\u9662\u58eb\u56e2\u961f\u5408\u4f5c\u7814\u53d1\uff0c\u53e6\u4e00\u6b3e\u7531\u82f1\u56fd\u725b\u6d25\u5927\u5b66\u5408\u4f5c\u56e2\u961f\u5f00\u53d1\u3002\u4ece\u5b9e\u9a8c\u7ed3\u679c\u6765\u770b\uff0c\u4e24\u6b3e\u75ab\u82d7\u5747\u80fd\u5b9e\u73b0\u5bf9\u65b0\u51a0\u75c5\u6bd2\uff08SARS-CoV-2\uff09\u7684\u514d\u75ab\u53cd\u5e94\uff0c\u5e76\u4e14\u8bf1\u5bfc\u9ad8\u6548\u7684T\u7ec6\u80de\u514d\u75ab\u5e94\u7b54\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1016\/S0140-6736\uff0820\uff0931605-6<\/div>\n
https:\/\/doi.org\/10.1016\/S0140-6736(20)31604-4<\/div>\n
\u00a0<\/div>\n
\u25a0 \u63ed\u793a\u65b0\u51a0\u80ba\u708e\u4e0e\u6d41\u611f\u7684\u514d\u75ab\u7279\u5f81\u5dee\u5f02<\/div>\n
\u8fd1\u65e5\uff0c\u4e2d\u56fd\u75be\u63a7\u4e2d\u5fc3\u4e0e\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u3001\u89e3\u653e\u519b\u603b\u533b\u9662\u7b49\u7b49\u673a\u6784\u8054\u5408\u7814\u7a76\u6210\u679c\u7cfb\u7edf\u63cf\u7ed8\u4e86\u65b0\u51a0\u60a3\u8005\u5916\u5468\u8840\u514d\u75ab\u7ec6\u80de\u7684\u6574\u4f53\u514d\u75ab\u53cd\u5e94\u7279\u5f81\uff0c\u53d1\u73b0\u65b0\u51a0\u80ba\u708e\u60a3\u8005\u514d\u75ab\u54cd\u5e94\u6a21\u5f0f\u4e0e\u53d1\u75c5\u8f7b\u91cd\u7a0b\u5ea6\u6709\u5bc6\u5207\u5173\u8054\u3002\u540c\u65f6\uff0c\u7814\u7a76\u5229\u7528\u5355\u7ec6\u80de\u6d4b\u5e8f\u7cfb\u7edf\u9610\u8ff0\u4e86\u65b0\u51a0\u548c\u7532\u6d41\u611f\u67d3\u514d\u75ab\u7279\u5f81\u7684\u5f02\u540c\u70b9\u3002\u8bba\u6587\u53d1\u8868\u5728Cell\u5b50\u520aImmunity\u6742\u5fd7\u4e0a\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1016\/j.immuni.2020.07.009<\/div>\n
\u00a0<\/div>\n
\u25a0 \u5f00\u53d1\u51fa\u65b0\u578b\u7684mRNA\u65b0\u51a0\u75ab\u82d7<\/div>\n
\u8fd1\u65e5\uff0c\u56fd\u5185\u7814\u7a76\u56e2\u961f\u5f00\u53d1\u51fa\u4e86\u4e00\u6b3e\u65b0\u578b\u7684mRNA\u65b0\u51a0\u75ab\u82d7\uff0c\u5728\u5c0f\u9f20\u548c\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u6a21\u578b\u4e2d\uff0c\u80fd\u591f\u6fc0\u53d1\u514d\u75ab\u53cd\u5e94\uff0c\u8bf1\u5bfc\u4ea7\u751f\u4e2d\u548c\u6297\u4f53\u3002\u8fd9\u6b3e\u65b0\u578b\u75ab\u82d7\u91c7\u7528\u7684\u5236\u5242\u6280\u672f\uff0c\u5b9e\u73b0\u5728\u5ba4\u6e29\u4e0b\u7a33\u5b9a\u5b58\u653e\u81f3\u5c11\u4e00\u5468\uff0c\u53ef\u964d\u4f4e\u8fd0\u8f93\u65f6\u51b7\u94fe\u8981\u6c42\u3002\u76ee\u524d\u8fd9\u6b3emRNA\u65b0\u51a0\u75ab\u82d7\u5df2\u83b7\u6279\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/div>\n
\u00a0<\/div>\n
\u63a8\u8350\u9605\u8bfb<\/div>\n
\u4e2d\u56fd\u766b\u75eb\u57fa\u56e01.0\u9879\u76ee\u5408\u4f5c\u8fbe\u6210<\/a><\/div>\n
\u5728\u7ebf\u9605\u8bfb2020\u5355\u7ec6\u80de\u884c\u7814\u62a5\u544a<\/a><\/div>\n
\u56fd\u5bb6\u751f\u7269\u4fe1\u606f\u4e2d\u5fc3\u65b9\u5411\u4e1c\uff1a\u57fa\u56e0\u5927\u6570\u636e\u53ca\u667a\u80fd\u5316<\/a><\/div>\n
\u3010\u58f0\u660e\u3011\u4e3a\u4f20\u64ad\u79d1\u5b66\u4fe1\u606f\uff0c\u63a8\u52a8\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u5b66\u7814\u8fde\u63a5\uff0c\u6211\u4eec\u79c9\u6301\u4e2d\u7acb\u3001\u4e13\u4e1a\u3001\u8d4b\u80fd\u7684\u7406\u5ff5\u6536\u96c6\u3001\u5206\u6790\u6216\u53d1\u5e03\u4fe1\u606f\u3002\u4f46\u7531\u4e8e\u65f6\u6548\u6027\u53ca\u884c\u4e1a\u7279\u6b8a\u6027\uff0c\u6240\u520a\u767b\u5185\u5bb9\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u4e0d\u4f5c\u4e3a\u51b3\u7b56\u4f9d\u636e\uff1b\u672c\u6587\u76f8\u5173\u4fe1\u606f\u4e0d\u4ee3\u8868\u57fa\u56e0\u6167\u673a\u6784\u7684\u89c2\u70b9\uff1b\u201c\u57fa\u56e0\u6167\u201d\u520a\u767b\u7684\u539f\u521b\u5185\u5bb9\u7684\u77e5\u8bc6\u4ea7\u6743\u4e3a\u201c\u57fa\u56e0\u6167\u201d\u5546\u6807\u62e5\u6709\u8005\u53ca\u76f8\u5173\u6743\u5229\u4eba\u6240\u6709\uff1b\u6b22\u8fce\u8f6c\u8f7d\uff0c\u8f6c\u8f7d\u8bf7\u7533\u8bf7\u5e76\u6ce8\u660e\u6765\u6e90\u3002\u6b22\u8fce\u4e2a\u4eba\u53ca\u673a\u6784\u6295\u7a3f\u53ca\u5408\u4f5c\u3002<\/div>\n\n
\n
\"RmFicvQBAkgAeFMK0ia5Cab3334OUN1mUBG4bibxEzJJC01MPtSxIgRZcJvf6IGrU6cWAaTKdqM8GkEbzxEfFiaWCQ\"\/<\/figure><\/div>","protected":false},"excerpt":{"rendered":"

\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u8d44\u8bafGeneMail 106 \u671f<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"close","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[996],"tags":[2012,2011],"class_list":["post-9065","post","type-post","status-publish","format-standard","hentry","category-news","tag-2012","tag-2011"],"_links":{"self":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9065","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/comments?post=9065"}],"version-history":[{"count":3,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9065\/revisions"}],"predecessor-version":[{"id":13769,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9065\/revisions\/13769"}],"wp:attachment":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/media?parent=9065"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/categories?post=9065"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/tags?post=9065"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}