{"id":9056,"date":"2020-08-07T21:18:57","date_gmt":"2020-08-07T13:18:57","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100015480&idx=1&sn=e52d82f5ff4a9ce2722df372a47fdea1&chksm=6b714fcf5c06c6d9cb7cd411761e05d4efe158788921f9e6a0279b0678d98941f34c2ef5034f#rd"},"modified":"2026-04-08T09:47:58","modified_gmt":"2026-04-08T01:47:58","slug":"5054100","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2020\/08\/07\/5054100\/","title":{"rendered":"2020\u5e74\u534a\u7a0b\uff0c\u57fa\u56e0\u884c\u4e1a\u8e0f\u6d6a\u800c\u6765"},"content":{"rendered":"

<\/p>\n

2020\u5e74\u4e0a\u534a\u5e74\uff0c\u75ab\u60c5\u201c\u5927\u8003\u201d\uff0c\u201c\u4eba\u7c7b\u7b2c\u4e00\u6b21\u5927\u89c4\u6a21\u4f7f\u7528\u5206\u5b50\u751f\u7269\u5b66\u68c0\u6d4b\u6280\u672f\u7b5b\u67e5\u6570\u5343\u4e07\u4eba\u201d\uff0c\u6781\u5927\u63a8\u52a8\u57fa\u56e0\u884c\u4e1a\u53d1\u5c55\u3002\u534a\u5e74\u6765\uff0c\u5168\u7403\u57fa\u56e0\u4f01\u4e1a\u878d\u8d44\u8fbe464.29\u4ebf\u5143\uff0c\u540c\u6bd4\u589e\u957f74%\uff0c\u4f46\u4ea7\u4e1a\u5c1a\u5728\u65e9\u671f\u9636\u6bb5\uff0c\u4e34\u5e8a\u4ecd\u6709\u5927\u91cf\u672a\u6ee1\u8db3\u9700\u6c42\uff0cmNGS\u3001\u57fa\u56e0\u6cbb\u7597\u7b49\u5e94\u7528\u6f5c\u529b\u5de8\u5927\u3002\u57fa\u56e0\u6167\u4e00\u5982\u65e2\u5f80\u76d8\u70b9\u57fa\u56e0\u884c\u4e1a\uff082019\u5e74\u540c\u671f\u5206\u6790<\/a>\uff09\uff0c\u4ee5\u4e0b\u662f\u4ea7\u4e1a\u6570\u636e\u53ca34\u4f4d\u653f\u4ea7\u5b66\u7814\u7528KOL\u8bbf\u8c08\u5206\u67902020\u534a\u7a0b\u3002<\/div>\n
\u9996\u53d1| \u57fa\u56e0\u6167<\/div>\n
\u7f16\u8f91 | \u6c6a\u4eae \u7f57\u6e58<\/div>\n
\u5173\u952e\u8bcd | \u57fa\u56e0\u884c\u4e1a\u76d8\u70b9<\/div>\n\n
\n
\"RmFicvQBAkgBibicdZwgXMZJTWibeGtiatM8eXaibMmib5GicSXKME8lgqPtSWXZYF4r3KUa3POXibuEydKVt6yicW61QsnA\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u8e0f\u6d6a\uff08\u6765\u6e90\/\u6444\u56fe\u7f51\uff0c\u7ecf\u6388\u6743\u4f7f\u7528\uff09<\/div>\n
\u4e3a\u4fbf\u4e8e\u9605\u8bfb\uff0c\u5217\u51fa\u6587\u7ae0\u63d0\u7eb2\u5982\u4e0b\uff1a<\/div>\n
\u4e00\u3001\u5b8f\u89c2\u73af\u5883\u53d8\u5316\uff1a\u00a0\u6539\u9769\u7684\u9635\u75db\u3001\u8fb9\u754c\u548c\u5206\u5de5<\/div>\n
\u4e8c\u3001\u4ea7\u4e1a\u5468\u671f\u7684\u5206\u5316\uff1a\u8d5b\u9053\u5206\u5316\u3001\u770b\u5929\u5403\u996d<\/div>\n
\u4e09\u3001\u4ea7\u54c1\u5316\u53ca\u5e94\u7528\u73b0\u72b6\uff1a\u5927Panel\/\u7532\u57fa\u5316\/\u57fa\u56e0\u6cbb\u7597<\/div>\n
\u56db\u3001\u65b0\u5174\u6280\u672f\u7684\u673a\u4f1a\uff1a\u57fa\u56e0\u5408\u6210\/mNGS\u5355\u7ec6\u80de<\/div>\n
\u4e94\u3001\u8d44\u672c\u5e76\u8d2d\uff1a\u57fa\u56e0\u884c\u4e1a\u751f\u6001\u6574\u5408<\/div>\n
\u516d\u3001\u672a\u6ee1\u8db3\u7684\u9700\u6c42\uff1a34\u4f4d\u653f\u4ea7\u5b66\u7814\u7528KOL\u8bbf\u8c08<\/div>\n
\u4e03\u3001\u8d8b\u52bf\u53ca\u98ce\u9669\u5206\u6790\uff1a\u4f1a\u6c34\u7684\u4eba\u72ec\u81ea\u6e38\u5f80\u6df1\u5904<\/div>\n
\n\n
\n
\"RmFicvQBAkgC6W96mrfXPjJ2LlBjWj9Nm7ZwRoDn212haXDHFhE4lRDs3Kyo9FYEQDuTviasdIEfsAdBUupV4cGw\"\/<\/figure><\/div>\n\n<\/div>\n
\u56fe\uff1a34\u4f4d\u4e13\u5bb6\u8c03\u7814\u540d\u5355\uff08\u6765\u6e90\/\u57fa\u56e0\u6167\uff09<\/div>\n
\u6ce8\uff1a\u4ee5\u4e0b\u4e3a\u5185\u5bb9\u7ec6\u8282\u3002\u66f4\u591a\u4ea7\u4e1a\u5206\u6790\u53ca\u8fdb\u5c55\u8ffd\u8e2a\u8bf7\u89c1\u57fa\u56e0\u6167\u5c06\u53d1\u5e03\u7684\u300a\u57fa\u56e0\u5927\u6570\u636e\u667a\u80fd\u751f\u4ea7\u53ca\u5206\u6790\u300b<\/a>\u884c\u7814\u62a5\u544a<\/a>\u3001\u300a\u4e2d\u56fd\u4e34\u5e8aNGS\u5e94\u7528\u9700\u6c42\u8c03\u7814\u300b\u84dd\u76ae\u4e66\u3001\u300a2021\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b\uff0c\u6b22\u8fce\u5173\u6ce8\u53ca\u51a0\u540d\u652f\u6301\u5408\u4f5c\u3002<\/div>\n
\u4e00\u3001\u5b8f\u89c2\u73af\u5883\u53d8\u5316<\/div>\n
1. \u56fd\u9645\u73af\u5883<\/div>\n
\u56fd\u9645\u73af\u5883\u7684\u4e0d\u7a33\u5b9a\u6027\u548c\u4e0d\u786e\u5b9a\u6027\u660e\u663e\u589e\u5f3a\u3002\u5bf9\u57fa\u56e0\u884c\u4e1a\u6709\u76f4\u63a5\u7684\u5f71\u54cd\uff0c\u5305\u62ec\uff1a\u5b9e\u4f53\u6e05\u5355\uff08\u4f8b\u59827\u670820\u65e5\uff0c\u534e\u5927\u7684\u4e24\u4e2a\u5b50\u516c\u53f8\u5217\u5165BIS\u5b9e\u4f53\u6e05\u5355\uff09\u3001\u6d77\u5916\u5e02\u573a\u7684\u8425\u5546\u73af\u5883\u3001\u751f\u4ea7\u8bbe\u5907\u7684\u82af\u7247\u4f9b\u5e94\u94fe\u53ca\u4e13\u5229\u7ea0\u7eb7\u7b49\u3002<\/div>\n
\u4ece\u53e6\u4e00\u65b9\u9762\uff0c\u56fd\u9645\u73af\u5883\u4e0b\u56fd\u5bb6\u660e\u786e\u7684\u201c\u4f9d\u9760\u79d1\u6280\u521b\u65b0\uff0c\u5b8c\u5584\u5b8f\u89c2\u8c03\u63a7\u8de8\u5468\u671f\u8bbe\u8ba1\u548c\u8c03\u8282\u201d\u7684\u6218\u7565\uff0c\u5bf9\u4e8e\u6b63\u8fdb\u5165\u6280\u672f\u8f6c\u5316\u671f\u7684\u57fa\u56e0\u884c\u4e1a\u5c06\u91ca\u653e\u4e00\u5b9a\u5468\u671f\u7684\u5bbd\u677e\u73af\u5883\uff08\u6b64\u5904\uff0c\u57fa\u56e0\u884c\u4e1a\u6db5\u76d6\u57fa\u56e0\u68c0\u6d4b\u3001\u57fa\u56e0\u6cbb\u7597\u3001\u57fa\u56e0\u5408\u6210\u3001DNA\u5b58\u50a8\u7b49\uff09\uff0c\u7279\u522b\u662f\u653f\u7b56\u5f00\u653e\u548c\u8d44\u672c\u6295\u5165\u3002<\/div>\n
2. \u7ecf\u6d4e\u73af\u5883<\/div>\n
\u622a\u6b628\u67086\u65e5\uff0c\u5168\u7403\u65b0\u51a0\u7d2f\u8ba1\u786e\u8bca1882.90\u4e07\u4eba\uff0c\u7d2f\u8ba1\u6b7b\u4ea170.84\u4e07\u4eba\uff08\u56fd\u5185\u7d2f\u8ba1\u786e\u8bca\u548c\u6b7b\u4ea1\u4eba\u6570\u5206\u522b\u4e3a8.89\u4e07\u4eba\u30014685\u4eba\uff09\u3002\u53d7\u65b0\u51a0\u75ab\u60c5\u548c\u590d\u6742\u56fd\u9645\u73af\u5883\u5f71\u54cd\uff0c\u4e16\u754c\u94f6\u884c\u57286\u6708\u4efd\u7684\u300a\u5168\u7403\u7ecf\u6d4e\u5c55\u671b\u300b\u62a5\u544a\u4e2d\u9884\u6d4b\uff0c2020\u5e74\u5168\u7403\u7ecf\u6d4e\u5c06\u4e0b\u6ed15.2%\u3002\u6839\u636e\u56fd\u5bb6\u7edf\u8ba1\u5c40\u6570\u636e\uff0c\u6211\u56fd\u4e0a\u534a\u5e74GDP\u6309\u53ef\u6bd4\u4ef7\u683c\u8ba1\u7b97\uff0c\u540c\u6bd4\u4e0b\u964d1.6%\uff0c\u7b2c\u4e8c\u5b63\u5ea6\u540c\u6bd4\u589e\u957f3.2%\u3002<\/div>\n
\u7ecf\u6d4e\u73af\u5883\u538b\u529b\u4e0b\uff0c\u4e00\u65b9\u9762\uff0c2020\u5e74\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u9884\u7b97\u51cf\u5c1122\u4ebf\uff08\u540c\u6bd4\u51cf\u5c117.1%\uff09\uff0c\u54cd\u5e94”\u8fc7\u7d27\u65e5\u5b50\u201d\u7684\u5f62\u52bf\u8981\u6c42\u3002\u53e6\u4e00\u65b9\u9762\uff0c\u56fd\u5bb6\u53d1\u6539\u59d4\u9996\u6b21\u660e\u786e\u5305\u62ec\u4eba\u5de5\u667a\u80fd\u30015G\u3001\u6570\u636e\u4e2d\u5fc3\u7b49\u201c\u79d1\u6280\u7aef\u201d\u6307\u5411\u7684\u65b0\u578b\u57fa\u7840\u8bbe\u65bd\u5efa\u8bbe\uff08\u65b0\u57fa\u5efa\uff09\uff0c\u521b\u4e1a\u677f\u201c\u63a5\u529b\u201d\u79d1\u521b\u677f\u8fdb\u5165\u6ce8\u518c\u5236\u8bd5\u70b9\uff0c\u65b0\u589e\u5929\u4f7f\u4eba\u5907\u6848\u5236\uff0c\u4ece\u9700\u6c42\u7aef\u548c\u8d44\u672c\u7aef\u52a0\u901f\u79d1\u6280\u521b\u65b0\u53ca\u4ea7\u4e1a\u5316\u3002\u5723\u6e58\u751f\u7269\u79d1\u521b\u677fIPO\u53d7\u7406\u4e09\u4e2a\u6708\u540e\u5373\u6210\u529f\u8fc7\u4f1a\uff0c\u52df\u8d445.57\u4ebf\u5143\u3002<\/div>\n
3. \u793e\u4f1a\u73af\u5883<\/div>\n\n
\n
\"RmFicvQBAkgCjyNQqZKzYk3iafoJvsaiaIFwoibufG27d7yPiafTnNEBHwpBT4fXSb9pbzKahN47xaM8ia4dliawA6Fiaw\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u7cbe\u51c6\u7597\u6cd5\u5360FDA\u6bcf\u5e74\u6279\u51c6\u65b0\u836f\u7684\u6bd4\u4f8b<\/div>\n
\uff08\u6765\u6e90\/\u836f\u660e\u5eb7\u5fb7\uff09<\/div>\n
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\u5728\u56fd\u52a1\u9662\u529e\u5370\u53d1\u300a\u6df1\u5316\u533b\u836f\u536b\u751f\u4f53\u5236\u6539\u97692020\u5e74\u4e0b\u534a\u5e74\u91cd\u70b9\u5de5\u4f5c\u4efb\u52a1\u300b\u4e2d\uff0c\u201c\u52a0\u5f3a\u516c\u5171\u536b\u751f\u4f53\u7cfb\u5efa\u8bbe\u201d\u5217\u4e3a\u7b2c\u4e00\u6761\uff0c\u4e3a\u6b64\uff0c2020\u5e74\u536b\u751f\u9886\u57df\u4e2d\u592e\u9884\u7b97\u5185\u6295\u8d44\u5b89\u6392456.6\u4ebf\u5143\u652f\uff0c\u7279\u522b\u5730\uff0c\u8981\u6c42\u786e\u4fdd\u79cb\u51ac\u5b63\u524d\u5b9e\u73b0\u5168\u56fd\u4e09\u7ea7\u7efc\u5408\u533b\u9662\u3001\u4f20\u67d3\u75c5\u533b\u9662\u3001\u5404\u7ea7\u75be\u63a7\u673a\u6784\u53ca\u53bf\u57df\u51851\u5bb6\u53bf\u7ea7\u533b\u9662\u5177\u5907\u6838\u9178\u68c0\u6d4b\u80fd\u529b\u3002<\/div>\n
\u9664\u4e86\u79d1\u521b\u677f\u3001\u521b\u4e1a\u6ce8\u518c\u5236\u5916\uff0c\u79d1\u6280\u90e8\u516c\u5e03\u300a\u5173\u4e8e\u63a8\u8fdb\u56fd\u5bb6\u6280\u672f\u521b\u65b0\u4e2d\u5fc3\u5efa\u8bbe\u7684\u603b\u4f53\u65b9\u6848\uff08\u6682\u884c\uff09\u300b\uff0c\u52302025\u5e74\u5e03\u5c40\u5efa\u8bbe\u82e5\u5e72\u56fd\u5bb6\u6280\u672f\u521b\u65b0\u4e2d\u5fc3\uff1b\u6b64\u5916\u6df1\u5733\u3001\u676d\u5dde\u7b49\u5730\u63a8\u51fa\u6570\u767e\u4ebf\u5143\u4ea7\u4e1a\u6bcd\u57fa\u91d1\uff0c\u57f9\u80b2\u6280\u672f\u521b\u4e1a\u4ea7\u4e1a\u5316\uff0c\u540c\u65f6\u52a0\u5feb\u534a\u5bfc\u4f53\u30015G\u3001\u4eba\u5de5\u667a\u80fd\u3001\u4ea7\u4e1a\u4e92\u8054\u7f51\u7b49\u53d1\u5c55\u53ca\u534f\u540c\uff0c\u5efa\u8bbe\u6570\u5b57\u7ecf\u6d4e\u65b0\u5f15\u64ce\u3002<\/div>\n
\u00a0<\/div>\n
4. \u884c\u4e1a\u73af\u5883<\/div>\n
\u5c3d\u7ba1\u4ee5\u4e0a\u63d0\u5230\u516c\u5171\u536b\u751f\u548c\u79d1\u6280\u521b\u65b0\u7684\u5f3a\u52b2\u9700\u6c42\u3001\u4e00\u7ea7\u548c\u4e8c\u7ea7\u8d44\u672c\u5e02\u573a\u652f\u6301\uff0c\u4f46\u884c\u4e1a\u73af\u5883\u4ecd\u6709\u4e24\u70b9\u91cd\u5927\u53d8\u5316\u9700\u9ad8\u5ea6\u91cd\u89c6\uff1a\u4e00\u662f\u56fd\u5bb6\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u7ba1\u7406\u3001\u57fa\u56e0\u7f16\u8f91\u80da\u80ce\u7eb3\u5165\u5211\u6cd5\u89c4\u5236\u8303\u56f4\uff0c\u300a\u751f\u7269\u5b89\u5168\u6cd5\u300b\u6709\u671b\u51fa\u53f0\uff0c\u4e3a\u884c\u4e1a\u754c\u5b9a\u4e0d\u53ef\u903e\u8d8a\u7684\u7ea2\u7ebf\uff1b\u4e8c\u662f\u5305\u62ecNGS\u53ca\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u7b49\u4f9b\u5e94\u94fe\u7684\u5784\u65ad\u4f53\u7cfb\u9010\u6b65\u5f62\u6210\uff0cLDT\u548cIVD\u4f53\u7cfb\u5c1a\u672a\u6210\u719f\uff0c\u5bf9\u4e8e\u4ea7\u4e1a\u53ca\u7ec8\u7aef\u8bae\u4ef7\u80fd\u529b\u53ca\u8d28\u91cf\u63a7\u5236\u53ef\u80fd\u57cb\u4e0b\u98ce\u9669\u3002<\/div>\n
\u7efc\u4e0a\uff1a\u57fa\u56e0\u884c\u4e1a\uff0c\u901a\u8fc7\u52a0\u901f\u91cd\u5927\u75be\u75c5\u53ca\u7f55\u89c1\u75c5\u7684\u57fa\u7840\u7814\u7a76\u548c\u6280\u672f\u521b\u65b0\uff0c\u4e3a\u80bf\u7624\u8bca\u7597\u3001\u51fa\u751f\u7f3a\u9677\u9632\u63a7\u53ca\u516c\u5171\u536b\u751f\u63d0\u4f9b\u89e3\u51b3\u65b9\u6848\uff1b\u4f5c\u4e3a\u65b0\u5174\u6218\u7565\u4ea7\u4e1a\u52a0\u901f\u4e8c\u7ea7\u5e02\u573a\u8d44\u672c\u5316\uff0c\u6709\u671b\u6210\u4e3a\u65b0\u7ecf\u6d4e\u5f15\u64ce\u4e4b\u4e00\uff0c\u4e3a\u533b\u7597\u6539\u9769\u53ca\u7ecf\u6d4e\u5185\u5faa\u73af\u5206\u89e3\u9635\u75db\uff1b\u6b63\u5feb\u901f\u79ef\u7d2f\u7684\u4e0a\u6e38\u521b\u65b0\u6280\u672f\u548c\u65b9\u6848\u8f93\u51fa\u201c\u4e00\u5e26\u4e00\u8def\u201c\u7b49\u4e3a\u6280\u672f\u8f93\u51fa\u63d0\u4f9b\u53ef\u80fd\u7684\u8def\u5f84\uff1b\u540c\u65f6\u7531\u4e8e\u57fa\u56e0\u884c\u4e1a\u7684\u7279\u6b8a\u6027\uff0c\u7ea2\u7ebf\u5df2\u7ecf\u8bbe\u7acb\uff0c\u5934\u90e8\u4f01\u4e1a\u548c\u4e2d\u5c0f\u4f01\u4e1a\u7684\u5206\u5de5\u4ecd\u9700\u5ba1\u614e\uff0c\u5feb\u901f\u6269\u5f20\u540c\u65f6\u9700\u5efa\u7acb\u4ef7\u503c\u94fe\u548c\u5e02\u573a\u7684\u8fb9\u754c\u3002<\/div>\n
\u00a0<\/div>\n
\u4e8c\u3001\u4ea7\u4e1a\u5468\u671f\u7684\u5206\u5316<\/div>\n\n
\n
\"RmFicvQBAkgCjyNQqZKzYk3iafoJvsaiaIFo1iaCefwib72LDyYTAicanOupOqQXiaZuZHhR71xVgHJD43s7vnwjHvGHQ\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u57fa\u56e0\u4ea7\u4e1a\u53ca\u4ea7\u54c1\u751f\u547d\u5468\u671f<\/div>\n
\uff08\u6765\u6e90\/\u57fa\u56e0\u6167\uff09<\/div>\n
1. \u4ea7\u4e1a\u9636\u6bb5<\/div>\n
\u8fd1\u5e74\u5168\u7403\u57fa\u56e0\u884c\u4e1a\u7684\u4ea7\u4e1a\u5316\uff0c\u672c\u8d28\u4e0a\u5f97\u76ca\u4e8e\u4e0b\u4e00\u4ee3\u9ad8\u901a\u91cf\u6d4b\u5e8f\u6280\u672f\u7684\u53d1\u5c55\u3002\u5386\u7ecf\u4e86\u4e94\u4e2a\u91cd\u8981\u9636\u6bb5\uff1a<\/div>\n
1999\u5e74\uff0c\u4eba\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u50ac\u5316\u57fa\u7840\u7814\u7a76<\/div>\n
2010\u5e74\uff0cHiseq\u6d4b\u5e8f\u4eea\u7cfb\u5217\u5b9e\u73b0\u79d1\u6280\u670d\u52a1\u89c4\u6a21\u5316<\/div>\n
2014\u5e74\uff0c\u57fa\u56e0\u68c0\u6d4b\u88ab\u53eb\u505c\u540e\u5239\u8f66<\/div>\n
2016\u5e74\uff0c\u56fd\u4ea7\u5316\u6d4b\u5e8f\u4eea\u91cf\u4ea7\u53ca\u540e\u7eed\u534e\u5927\u57fa\u56e0\u4e0a\u5e02<\/div>\n
2018\u5e74\uff0cONT\u63a8\u51fa\u9ad8\u901a\u91cf\u6d4b\u5e8f\u8bbe\u5907\u5e76\u52a0\u901f\u5e02\u573a\u670d\u52a1<\/div>\n
2020\u5e74\uff0c\u65b0\u51a0\u75ab\u60c5\u4f7f\u7528\u5927\u89c4\u6a21\u6838\u9178\u68c0\u6d4b<\/div>\n\n
\n
\"RmFicvQBAkgDfsiadpUNZonu0bCyYaFxqVxTYEL9rdYHUSH6dq0o0RpMziaTZRaL8NOtEsTiavCub4UT4Xkf2MZugA\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u56fd\u51852020\u4e0a\u534a\u5e74\u57fa\u56e0\u884c\u4e1a\u878d\u8d44\u8f6e\u6b21\u70ed\u5ea6\u53ca\u91d1\u989d\u5206\u6790<\/div>\n
\uff08\u6765\u6e90\/\u57fa\u56e0\u6167\uff09<\/div>\n
\u7ecf\u8fc7\u5341\u4f59\u5e74\u7684\u6280\u672f\u53ca\u4ea7\u4e1a\u53d1\u5c55\uff0c\u57fa\u56e0\u884c\u4e1a\u7684\u4ef7\u503c\u94fe\u521d\u6b65\u5f62\u6210\uff0c\u5c24\u5176\u5728\u516c\u5171\u536b\u751f\u6392\u67e5\u53ca\u76d1\u6d4b\u65b9\u9762\u53d1\u6325\u4e0d\u53ef\u66ff\u4ee3\u7684\u4f5c\u7528\u3002\u4e0a\u534a\u5e74\uff0c\u5168\u7403\u516c\u5f00\u7684\u57fa\u56e0\u4f01\u4e1a\u878d\u8d44\u91d1\u989d\u8fbe66.16\u4ebf\u7f8e\u5143(\u7ea6464.29\u4ebf\u5143\u4eba\u6c11\u5e01\uff09\uff0c\u540c\u6bd4\u589e\u957f74%\u3002\u5176\u4e2d\uff0c\u6211\u56fd\u57fa\u56e0\u4f01\u4e1a\u878d\u8d4425.37\u4ebf\u7f8e\u5143\uff08\u7ea6178.04\u4ebf\u5143\u4eba\u6c11\u5e01\uff09\uff0c\u540c\u6bd4\u589e\u957f287%\u3002<\/div>\n
\u5c3d\u7ba1\u5982\u6b64\uff0c\u4ee5\u4ece\u6280\u672f\u89d2\u5ea6\uff0cdPCR\u3001NGS\u3001\u5355\u5206\u5b50\u6d4b\u5e8f\u3001\u5149\u5b66\u56fe\u8c31\u7b49\u6280\u672f\u4ecd\u5728\u4e0d\u65ad\u4f18\u5316\u6216\u4ea7\u54c1\u5316\u4e2d\uff1b\u4ece\u4ea7\u54c1\u89d2\u5ea6\uff0c\u76ee\u524d\u53ea\u6709NIPT\uff08\u65e0\u521b\u4ea7\u524d\u57fa\u56e0\u68c0\u6d4b\uff09\u548cDNA\u53f8\u6cd5\u9274\u5b9a\u4e24\u4e2a\u4ea7\u54c1\u6210\u719f\uff1b\u4ece\u4f01\u4e1a\u89d2\u5ea6\uff0c\u76ee\u524d\u5c1a\u6ca1\u6709\u4e00\u5bb6\u516c\u53f8\u5b8c\u5168\u72ec\u7acb\u63d0\u4f9b\u6574\u5957\u89e3\u51b3\u65b9\u6848\u4ee5\u53ca\u5efa\u7acb\u6301\u7eed\u7684\u76c8\u5229\u6a21\u5f0f\u3002<\/div>\n
\u00a0<\/div>\n
\u800c\u5728\u7b2c\u4e8c\u66f2\u7ebf\u4e0a\uff0c\u4ee5\u5355\u7ec6\u80de\u3001\u5355\u5206\u5b50\u6d4b\u5e8f\u523a\u6fc0\u4e86\u840e\u9761\u7684\u79d1\u6280\u670d\u52a1\u5e02\u573a\uff1b\u57fa\u56e0\u6cbb\u7597\u548c\u57fa\u56e0\u5408\u6210\uff0c\u5c06\u57fa\u56e0\u6d4b\u5e8f\u7684\u4ef7\u503c\u653e\u5927\uff0c\u7ed3\u5408\u5230\u533b\u836f\u548c\u5de5\u4e1a\u4e2d\u3002\u4ecd\u5904\u4e8e\u5f15\u5165\u6216\u53d1\u5c55\u671f\u3002<\/div>\n
\u56e0\u6b64\uff0c\u4e00\u7ea7\u548c\u4e8c\u7ea7\u5e02\u573a\u7684\u706b\u70ed\uff0c\u53ef\u4ee5\u7406\u89e3\u4e3a\u57fa\u56e0\u884c\u4e1a\u5728\u7a81\u53d1\u60c5\u51b5\u4e0b\u7684\u89e3\u51b3\u65b9\u6848\uff0c\u4e5f\u53ef\u4ee5\u8bf4\u662f\u201c\u770b\u5929\u5403\u996d\u201d\uff0c\u884c\u4e1a\u5468\u671f\u672c\u8d28\u53d1\u5c55\u901f\u7387\u4f4e\u4e8e\u5f53\u4e0b\u9884\u671f\uff0c\u672a\u6765\u5c06\u56de\u5f52\u51b7\u9759\uff0c\u7ee7\u7eed\u57f9\u80b2\u3002<\/div>\n\n
\n
\"RmFicvQBAkgDfsiadpUNZonu0bCyYaFxqVB1PgzPngGUvibDn10JX25icabkDubmia1icdnFC9JGTanzJIO6lvmrbErQ\"\/<\/figure><\/div>\n\n
\u56fe\uff1a2020\u4e0a\u534a\u5e74\u57fa\u56e0\u884c\u4e1a\u878d\u8d44\u8f6e\u6b21\u70ed\u5ea6<\/div>\n
\uff08\u6765\u6e90\/\u57fa\u56e0\u6167\uff09<\/div>\n
\u8fd9\u4ece\u4e0a\u534a\u5e74\u878d\u8d44\u6570\u636e\u4e2d\u53ef\u4ee5\u5f97\u5230\u8fdb\u4e00\u6b65\u8bc1\u5b9e\uff0c\u56fd\u518547\u8d77\u57fa\u56e0\u4f01\u4e1a\u878d\u8d44\u4e8b\u4ef6\u4e2d\uff0cA\u8f6e\u548cB\u8f6e\u878d\u8d44\u4e8b\u4ef6\u6b21\u6570\u8fbe\u523062%\uff0c\u800c\u4ec5B\u8f6e\u878d\u8d44\u603b\u8ba182.2\u4ebf\u5143\u4eba\u6c11\u5e01\uff0c\u8d85\u8fc7\u878d\u8d44\u603b\u989d\u768450%\u3002<\/div>\n
\u56e0\u6b64\uff0c\u57fa\u56e0\u884c\u4e1a\u6574\u4f53\u5904\u4e8e\u53d1\u5c55\u65e9\u671f\uff0c\u5728\u57fa\u56e0\u68c0\u6d4b\u65b9\u5411\uff0c\u9664\u4e86\u751f\u80b2\u3001\u80bf\u7624\u4f34\u968f\u8bca\u65ad\u7b49\u5c11\u6570\u6210\u719f\u8d5b\u9053\uff0c\u5927\u90e8\u5206\u4ecd\u5728\u4ea7\u54c1\u5316\u9636\u6bb5\uff1b\u5bf9\u4e8e\u57fa\u56e0\u6cbb\u7597\u548c\u57fa\u56e0\u5408\u6210\u4ecd\u5728\u7814\u53d1\u671f\uff0cDNA\u5b58\u50a8\u7b49\u65b0\u5174\u6280\u672f\u5728\u840c\u82bd\u4e2d\u3002<\/div>\n
\u00a0<\/div>\n
2. \u4e0a\u6e38\u7684\u5784\u65ad<\/div>\n
\u5728\u6574\u4f53\u884c\u4e1a\u53d1\u5c55\u65e9\u671f\u9636\u6bb5\uff0c\u4f5c\u4e3a\u6838\u5fc3\u7684\u4e0a\u6e38\u4f9b\u5e94\u94fe\u4e2d\uff08\u4ee5\u6d4b\u5e8f\u4e3a\u4f8b\uff09\uff0c\u6d4b\u5e8f\u4eea\u82af\u7247\u4f9b\u5e94\u5546\u5904\u4e8e\u6781\u5927\u4e0d\u786e\u5b9a\u4e2d\uff0c\u800c\u6d4b\u5e8f\u4eea\u751f\u4ea7\u5546\u4ece\u5934\u90e8\u6548\u5e94\u53ca\u4ea7\u54c1\u5f62\u6001\u4e0a\u6b63\u5728\u6784\u5efa\u5784\u65ad\u3002\u4e2d\u4e0b\u6e38\u7f3a\u4e4f\u8bae\u4ef7\u6743\uff0c\u4ee5\u5404\u7ea7\u653f\u5e9c\u3001\u8d44\u672c\u7b49\u5934\u90e8\u4f01\u4e1a\u4e4b\u95f4\u5f00\u59cb\u51fa\u73b0\u4e0d\u540c\u7a0b\u5ea6\u7684\u53cd\u5784\u65ad\u3002<\/div>\n
2018\u5e7411\u6708Illumina\u62df\u4ee512\u4ebf\u7f8e\u5143\u6536\u8d2d PacBio\uff0c\u968f\u540e\u906d\u5230\u82f1\u56fd\u7ade\u4e89\u548c\u5e02\u573a\u7ba1\u7406\u5c40\uff08CMA\uff09\u548c\u7f8e\u56fd\u8054\u90a6\u8d38\u6613\u59d4\u5458\u4f1a\uff08FTC\uff09\u7684\u7ec4\u7ec7\uff0c\u4e8e2020\u5e741\u6708\u5ba3\u5e03\u4e2d\u6b62\u3002\u540c\u65f6\uff0c\u57fa\u56e0\u6167\u6ce8\u610f\u5230\uff0c6\u6708\uff0cIllumina\u4ee5\u52a0\u901f\u5668\u540d\u4e49\u6295\u8d44\u5305\u62ec\u795e\u7ecf\u6027\u75be\u75c5\u3001\u764c\u75c7\u3001\u6297\u4f53\u836f\u3001\u7ed3\u6838\u75c5\u8010\u836f\u3001\u5916\u6ccc\u4f53\u3001\u519c\u4e1a\u5fae\u751f\u7269\u3001\u57fa\u56e0\u7f16\u8f91\u76f8\u51737\u5bb6\u521d\u521b\u4f01\u4e1a\u516c\u53f8\u3002<\/div>\n
2020\u5e743\u6708\uff0c\u534e\u5927\u57fa\u56e0\u5728\u7f8e\u56fd\u4f5b\u7f57\u91cc\u8fbe\u5dde\u7684DNA\u6280\u672f\u4f1a\u8bae\u4e0a\u5ba3\u5e03\u5c06\u63d0\u4f9b\u201c\u6781\u7aef\u201dDNA\u6d4b\u5e8f\u7cfb\u7edf\uff0c\u6bcf\u5e74\u53ef\u89e3\u780110\u4e07\u4eba\u7684\u57fa\u56e0\u7ec4\uff0c\u5c06\u9996\u6b21\u7a81\u7834100\u7f8e\u5143\u7684\u58c1\u5792\u30026\u6708\uff0c\u7f8e\u56fd\u8054\u90a6\u6cd5\u9662\u4e0b\u8fbe\u521d\u6b65\u7981\u4ee4\uff0c\u4ee5\u4e13\u5229\u4fb5\u6743\u7981\u6b62\u534e\u5927\u57fa\u56e0\u53ca\u5176\u5b50\u516c\u53f8\uff08\u5305\u62ec\u534e\u5927\u667a\u9020MGI\uff09\u5728\u7f8e\u56fd\u5206\u9500\u548c\u63a8\u5e7f\u5176\u57fa\u56e0\u6d4b\u5e8f\u5e73\u53f0\u3002<\/div>\n
\u00a0<\/div>\n
\u800c\u5bf9\u4e8e\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u6280\u672f\uff0c\u9f50\u78b3\u79d1\u6280\u521b\u59cb\u4eba\u8c22\u4e39\u6559\u6388\u8868\u793a\u884c\u4e1a\u4e0a\u6e38\u7684\u6d4b\u5e8f\u4eea\u5668\u548c\u914d\u5957\u8bd5\u5242\u8fd8\u5904\u4e8e\u88ab\u5355\u4e00\u56fd\u5916\u4f01\u4e1a\u5784\u65ad\u7684\u5c40\u9762\uff0c\u800c\u884c\u4e1a\u4e0b\u6e38\u7684\u5e94\u7528\u4e8e\u670d\u52a1\u5e02\u573a\u5df2\u7ecf\u51fa\u73b0\u7206\u53d1\u5f0f\u589e\u957f\u3002<\/div>\n
\u9664\u4e86\u4ea7\u4e1a\u8d44\u6e90\u8679\u5438\u6548\u5e94\uff0c\u5934\u90e8\u4f01\u4e1a\u7279\u522b\u662f\u4e0a\u5e02\u4f01\u4e1a\u5728\u8d44\u672c\u6760\u6746\u4e0b\uff0c\u8bbe\u7acb\u4ea7\u4e1a\u57fa\u91d1\u5feb\u901f\u5efa\u7acb\u5c40\u90e8\u751f\u6001\u94fe\uff0cIllumina\u9664\u4e86\u65e9\u671f\u6536\u8d2dSolexa\u5b8c\u6210\u6218\u7565\u8f6c\u578b\u5916\uff0c\u5bf9\u5916\u6295\u8d44\u8d85\u8fc724\u5bb6\u4ea7\u4e1a\u94fe\u4e0a\u4e2d\u6e38\u4f01\u4e1a\uff1b\u5728\u4ea7\u4e1a\u521b\u6295\u57fa\u91d1\u65b9\u9762\uff0c\u534e\u5927\u57fa\u56e0\u53c2\u6295\u4e86\u8584\u8377\u5929\u4f7f\u57fa\u91d1\u3001\u96c5\u60e0\u7cbe\u51c6\u533b\u7597\u57fa\u91d1\u3001\u9ad8\u6797\u539a\u5065\u521b\u6295\u57fa\u91d1\u3001\u677e\u79be\u533b\u5065\u57fa\u91d1\u3001\u534e\u5927\u5171\u8d62\u57fa\u91d1\u7b49\uff1b\u8d1d\u745e\u57fa\u56e0\u4e5f\u5df2\u5b8c\u6210\u79c1\u52df\u57fa\u91d1\u7ba1\u7406\u4eba\u5907\u6848\u3002\u5728\u884c\u4e1a\u53d1\u5c55\u4ecd\u5728\u65e9\u671f\u9636\u6bb5\uff0c\u6b64\u73b0\u8c61\u53ef\u80fd\u5e26\u6765\u4e00\u5b9a\u7684\u53cd\u5f39\uff0c\u5305\u62ec\u76d1\u7ba1\u3001\u5e02\u573a\u53ca\u521b\u65b0\u901f\u7387\u3002<\/div>\n
\u57fa\u56e0\u6167\u9884\u8ba1\uff0c\u5728NGS\u3001\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u53cadPCR\u7b49\u8bbe\u5907\u7814\u53d1\u9886\u57df\uff0c\u56fd\u6709\u8d44\u672c\u53ca\u5730\u65b9\u653f\u5e9c\u5c06\u63a8\u52a8\u533a\u57df\u9f99\u5934\u4f01\u4e1a\uff0c\u5747\u8861\u5e02\u573a\u53d1\u5c55\uff1b\u5934\u90e8\u4f01\u4e1a\u5728\u5feb\u901f\u6269\u5f20\u540c\u65f6\u4e5f\u5e94\u9ad8\u5ea6\u91cd\u89c6\u5e02\u573a\u5f62\u6001\u3002<\/div>\n
\u00a0<\/div>\n
3. \u8d44\u672c\u5e26\u6765\u7684\u8d5b\u9053\u5206\u5316<\/div>\n\n
\n
\"RmFicvQBAkgDfsiadpUNZonu0bCyYaFxqVibhKYndXjicWZMUhlLiavP9hgdebGtYc58vJ3W7MsvKicYKCcLaiaptqO9Q\"\/<\/figure><\/div>\n\n
\u56fe\uff1a2020\u4e0a\u534a\u5e74\u5168\u7403\u57fa\u56e0\u884c\u4e1a\u878d\u8d44\u8d5b\u9053\u70ed\u5ea6\u5206\u6790<\/div>\n
\uff08\u6765\u6e90\/\u57fa\u56e0\u6167\uff09<\/div>\n
\u4ece\u57fa\u56e0\u6167\u7edf\u8ba1\u7684\u5168\u74032020\u4e0a\u534a\u5e74\u57fa\u56e0\u884c\u4e1a\u878d\u8d44\u8d5b\u9053\u70ed\u5ea6\u56fe\u6765\u770b\uff0c\u8d5b\u9053\u5206\u5316\u73b0\u8c61\u5f00\u59cb\u660e\u663e\uff0c\u80bf\u7624\u57fa\u56e0\u7ec4\u3001\u57fa\u56e0\u6cbb\u7597\u548c\u751f\u4ea7\u8bbe\u5907\u8f83\u53d7\u9752\u7750\uff1b\u540c\u65f6\uff0c\u56fd\u5185\u5916\u8d44\u672c\u5173\u6ce8\u5ea6\u5448\u73b0\u8f83\u5927\u5dee\u522b\uff0c\u7279\u522b\u662f\u5728\u57fa\u56e0\u5927\u6570\u636e\u3001\u57fa\u56e0\u6cbb\u7597\u3001\u86cb\u767d\u8d28\u7ec4\u5b66\u7b49\u65b9\u9762\uff0c\u6d77\u5916\u8d44\u672c\u5e03\u5c40\u8f83\u4e3a\u5747\u8861\uff0c\u800c\u56fd\u5185\u8d44\u672c\u624e\u5806\u5728\u80bf\u7624\u57fa\u56e0\u7ec4\u53ca\u751f\u4ea7\u8bbe\u5907\u8d5b\u9053\u3002<\/div>\n
\u5c24\u5176\u662f\u80bf\u7624\u8d5b\u9053\u6210\u4e3a2020\u5e74\u70ed\u70b9\uff0c6\u6708\u71c3\u77f3\u533b\u5b66(BNR.US)\u548c\u6cdb\u751f\u5b50(GTH.US)\u5148\u540e\u5728\u7f8e\u56fd\u7eb3\u65af\u8fbe\u514b\u4e0a\u5e02\uff0c\u52df\u8d44\u5747\u8d852\u4ebf\u7f8e\u5143\uff0c\u622a\u6b62\u53d1\u7a3f\u65e5\u5e02\u503c\u76f8\u5dee1\u500d\u3002\u8bfa\u79be\u81f4\u6e90\u5f00\u542f\u79d1\u521b\u677fIPO\u7533\u8bf7\uff0c\u62df\u52df\u8d445.04\u4ebf\u5143\uff0c\u91cd\u70b9\u53d1\u5c55\u9057\u4f20\u75c5\u548c\u80bf\u7624\u9886\u57dfIVD\u4ea7\u54c1\u548c\u6570\u636e\u4e2d\u5fc3\u5efa\u8bbe\u7b49\u3002\u76ee\u524d\uff0c\u6211\u4eec\u80bf\u7624\u9886\u57df\u7684\u4f34\u968f\u8bca\u65ad\u4ea7\u54c1\u4ec5\u83b7\u62796\u6b3e\uff0c\u4e14\u5747\u96c6\u4e2d\u5728\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u5c0fPanel\u4e2d\uff1b\u76f8\u5bf9\u800c\u8a00\uff0cFDA\u6279\u51c6\u4e8642\u6b3e\u4f34\u968f\u8bca\u65ad\u4ea7\u54c1\uff08\u4e0d\u9650\u4e8eNGS\u65b9\u6cd5\uff09\u3002<\/div>\n
\u8fd9\u91cc\u53ef\u80fd\u51fa\u73b0\u4e00\u5b9a\u7a0b\u5ea6\u7684\u8fc7\u70ed\uff0c\u540c\u6837\u7684\u73b0\u8c61\u4e5f\u53ef\u80fd\u53d1\u751f\u5728\u4f20\u611f\u67d3\u9886\u57df\u3002<\/div>\n
\u00a0<\/div>\n
4. \u4ef7\u503c\u94fe\u7684\u652f\u6301\u6d3b\u52a8<\/div>\n
\u4ee5\u4e0a\u8c08\u5230\u907f\u514d\u8fc7\u70ed\u65f6\uff0c\u662f\u7406\u8bba\u4e0a\u5bf9\u4e2a\u4f53\u4f01\u4e1a\u3001\u5c40\u90e8\u8d5b\u9053\u7684\u671f\u671b\u503c\u7ba1\u7406\u4e0e\u884c\u4e1a\u6574\u4f53\u521b\u65b0\u521b\u4e1a\u6295\u5165\u53ca\u653f\u7b56\u606f\u606f\u76f8\u5173\uff1b\u867d\u7136\uff0c\u4e3b\u89c2\u4e0a\u201c\u770b\u591a\u201d\u548c\u201c\u770b\u7a7a\u201d\u662f\u8f6e\u56de\u7684\u5468\u671f\u3002<\/div>\n
\u5ba2\u89c2\u5982\u4f55\u5224\u65ad\uff1f\u4ece\u4f01\u4e1a\u63a8\u5e7f\u53ca\u8d5b\u9053\uff0c\u9664\u4e86\u4ee5\u4e0a\u63d0\u5230\u751f\u4ea7\u7ecf\u8425\u3001\u9500\u552e\u7b49\u4ef7\u503c\u94fe\u4e3b\u4f53\u6d3b\u52a8\uff0c\u53ef\u4ee5\u4ece\u652f\u6301\u6d3b\u52a8\u6765\u5224\u65ad\u3002\u4f8b\u5982\u4f9b\u5e94\u94fe\u3001\u6280\u672f\u5f00\u53d1\u3001\u4eba\u624d\u3001\u521b\u65b0\u5e73\u53f0\u7b49\u7efc\u5408\u5224\u65ad\u3002\u76ee\u524d\u57fa\u56e0\u884c\u4e1a\u8d5b\u9053\u4e3b\u8981\u5206\u4e3a\u65e9\u671f\u7814\u53d1\u548c\u4ea7\u54c1\u5b75\u5316\uff0c\u4ee5\u4e0b\u6211\u4eec\u4ece\u4ea7\u54c1\u5316\u53ca\u65b0\u5174\u6280\u672f\u4e24\u4e2a\u89d2\u5ea6\u63a2\u8ba8\u3002<\/div>\n
\u00a0<\/div>\n
\u300a\u4e2d\u56fd\u4e34\u5e8aNGS\u5e94\u7528\u9700\u6c42\u8c03\u7814\u62a5\u544a\u300b<\/div>\n
\u51a0\u540d\u5408\u4f5c\u62db\u52df\u4e2d\u25bc<\/div>\n\n
\n
\"640?wx_fmt=png\"\/<\/figure><\/div>\n\n
\u4e09\u3001\u4ea7\u54c1\u5316\u53ca\u5e94\u7528\u73b0\u72b6<\/div>\n
1. 2020\u5e74\u4e0a\u534a\u5e74\u83b7\u6279\u7684\u4ea7\u54c1<\/div>\n
\u9996\u5148\uff0c\u5728\u65b0\u51a0\u75c5\u6bd2\uff08\u00a0COVID-19\uff09\u68c0\u6d4b\u4e0a\uff0cFDA\u7d27\u6025\u5ba1\u6279\u4e86IVD\u4ea7\u54c1168 \u4e2a\uff0cLDT 35\u4e2a\uff0cNMPA\u6279\u51c6\u4e8643\u6b3e\u8bd5\u5242\u76d2\u30011\u6b3e\u8f6f\u4ef6\u548c1\u6b3e\u6d4b\u5e8f\u4eea\uff1b43\u6b3e\u8bd5\u5242\u76d2\u4e2d\uff0c\u6838\u9178\u68c0\u6d4b\u8bd5\u5242\u76d2\u5360\u636e52%\u3002\uff08\u8be6\u60c5\u8bf7\u89c1YourMap\u6570\u636e\u5e93<\/a>\u53ca\u6b63\u5728\u7b56\u5212\u7684\u300a\u4e2d\u56fd\u4e34\u5e8aNGS\u5e94\u7528\u9700\u6c42\u8c03\u7814\u300b\u84dd\u76ae\u4e66\uff09\u3002<\/div>\n
\u00a0<\/div>\n
\u5728\u4f34\u968f\u8bca\u65ad\u65b9\u9762\uff0c\u4e0a\u534a\u5e74\uff0cFDA\u6279\u51c6\u4e86\u56db\u6b3eNGS\u4f34\u968f\u8bca\u65ad\u53ca\u7cbe\u51c6\u7597\u6cd5\uff0c\u5305\u62ec Roche\u7684cobas EZH2 Mutation Test\u548cFoundation Medicine\u7684F1CDX\u3002\u5176\u4e2dcobas EZH2 \u5bf9\u5e94Epizyme\u516c\u53f8\u7684\u6cbb\u7597\u4e0a\u76ae\u6837\u8089\u7624\u7684\u8868\u89c2\u9057\u4f20\u5b66\u836f\u7269Tazverik(tazemetostat)\uff1bF1CDX\u6269\u5c55\u4e86\u4e09\u6b3e\u7cbe\u51c6\u7597\u6cd5\u7684\u4f34\u968f\u8bca\u65ad\uff1a<\/div>\n
\u00b7\u00a0Tabrecta(capmatinib)\u2014\u2014\u6765\u81ea\u8bfa\u534e\uff0c\u7528\u4e8e\u6cbb\u7597MET14\u53f7\u5916\u663e\u5b50\u8df3\u8dc3\u7a81\u53d8(METex14)\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c;<\/div>\n
\u00b7\u00a0Pemazyre(pemigatinib)\u2014\u2014\u6765\u81eaIncyte\uff0c\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u6cbb\u7597\u7684\u643a\u5e26\u6210\u7ea4\u7ef4\u7ec6\u80de\u751f\u957f\u56e0\u5b50\u53d7\u4f532(FGFR2)\u878d\u5408\u6216\u91cd\u6392\u7684\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u80c6\u7ba1\u764c\u9776\u5411\u836f\uff1b<\/div>\n
\u00b7\u00a0Keytruda\u2014\u2014\u6765\u81ea\u9ed8\u6c99\u4e1c\u516c\u53f8\uff0c\u7528\u4e8e\u6cbb\u7597\u9ad8\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\uff08TMB-H\uff09\u4e14\u65e2\u5f80\u6cbb\u7597\u540e\u75be\u75c5\u8fdb\u5c55\u7684\u65e0\u6cd5\u5207\u9664\u6216\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\u60a3\u8005\u3002<\/div>\n
\u00a0<\/div>\n
\u7279\u522b\u5730\uff0c\u6b64\u6b21Keytruda\uff08\u201dK\u836f\u201c\uff09\u65b0\u9002\u5e94\u75c7\u4ee5\u53ca\u5bf9\u5e94F1CDX\u4f34\u968f\u8bca\u65ad\u7684\u83b7\u6279\uff0c\u662fTMB\u4f5c\u4e3aIVD\u6807\u5fd7\u7269\u540e\uff0c\u9996\u6b21\u83b7\u6279\u4e3a\u4f34\u968f\u8bca\u65ad\uff0c\u7ee7MSI\/dMMR\u4e4b\u540e\u6210\u4e3a\u7b2c\u4e8c\u4e2a\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u6cdb\u764c\u79cd\u4f34\u968f\u8bca\u65ad\u6807\u5fd7\u7269\uff0c\u662f\u7b2c\u4e09\u4e2a\u6cdb\u764c\u79cd\uff08\u201dtissue-agnostic\u201c\uff0c\u5373\u4e0e\u7ec4\u7ec7\u65e0\u5173\uff09\u6807\u5fd7\u7269\u3002<\/div>\n
\u9664\u4e86\u65b0\u51a0\u75c5\u6bd2\u6838\u9178\u68c0\u6d4b\u548c\u4f34\u968f\u8bca\u65ad\uff0c\u65b0\u4e00\u6b3e\u5927Panel\uff0c\u5373\u6765\u81eaPersonal Genome Diagnostics\u7684PGDx Elio Tissue Complete\uff0c\u57282020\u5e744\u6708\u83b7\u5f97FDA\u8ba4\u8bc1\uff08clearance\uff09\u3002<\/div>\n
\u56fd\u5185\uff0c\u7ee72018-2019\u5e74\u6279\u51c66\u6b3eNGS\u4f34\u968f\u8bca\u65ad\u5c0fPanel\u540e\uff0c2020\u5e74NMPA\u4ec5\u6279\u51c6\u4e86\u4e00\u6b3eNGS\u4f34\u968f\u8bca\u65ad\uff0c\u5373\u6cdb\u751f\u5b50\u7684\u4eba\u7c7b8\u57fa\u56e0\u7a81\u53d8\u8054\u5408\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08\u534a\u5bfc\u4f53\u6d4b\u5e8f\u6cd5\uff09\u3002\u540c\u65f6\u4e16\u548c\u57fa\u56e0\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7ec4\u7ec7TMB\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08\u53ef\u9006\u672b\u7aef\u7ec8\u6b62\u6d4b\u5e8f\u6cd5\uff09\u7b49\u8fdb\u5165\u521b\u65b0\u533b\u7597\u5668\u68b0\u7279\u522b\u5ba1\u67e5\u7a0b\u5e8f\u3002\u534e\u5927\u7684BRCA1\/2 \u57fa\u56e0\u7a81\u53d8\u68c0\u6d4b\u8bd5 \u5242\u76d2(\u8054\u5408\u63a2\u9488\u951a\u5b9a\u805a\u5408\u6d4b\u5e8f\u6cd5)\u7533\u62a5\u533b\u7597\u5668\u68b0\u6ce8\u518c\uff08\u6b63\u5728\u53d7\u7406\uff09\u3002<\/div>\n
\u6b64\u5916\uff0cNMPA\u6279\u51c6\u4e86\u4e00\u6b3eNGS\u8f85\u52a9\u8bca\u65ad\u8bd5\u5242\u76d2\uff0c\u5373\u534e\u5927\u57fa\u56e0\u7684\u5168\u8d44\u5b50\u516c\u53f8\u7684\u9057\u4f20\u6027\u8033\u804b\u57fa\u56e0\u68c0\u6d4b\u8bd5\u5242\u76d2(\u8054\u5408\u63a2\u9488\u951a\u5b9a\u805a\u5408\u6d4b\u5e8f\u6cd5)\u3002<\/div>\n
\u00a0<\/div>\n
2. \u4ea7\u54c1\u5316\u7684\u70ed\u70b9<\/div>\n
1\uff09\u80bf\u7624\u5927Panel<\/div>\n
\u968f\u7740\u6cdb\u764c\u79cd\u65b0\u836f\u83b7\u6279\u5728\u4e2d\u56fd\u4eba\u7fa4\u9002\u5e94\u75c7\u7684\u6269\u5c55\u4ee5\u53ca\u80bf\u7624\u7b5b\u67e5\u7b49\u9700\u6c42\uff0c\u80bf\u7624\u5927Panel\u6709\u671b\u5728\u672a\u67652-3\u5e74\u52a0\u901f\u83b7\u6279\u30025\u67089\u65e5\uff0c\u71c3\u77f3\u533b\u5b66\u4e0eIllumina\u5408\u4f5c\u5c06ctDNA\u548c\u5927Panel\u63a8\u5411IVD\uff1b\u540c\u5e74\uff0c\u548c\u745e\u57fa\u56e0\u548c\u4e0a\u6d77\u80f8\u79d1\u533b\u9662\u5408\u4f5c\u542f\u52a8\u5927Panel\u591a\u4e2d\u5fc3\u80ba\u764c\u7814\u7a76\u9879\u76ee\uff1b\u6b64\u524d\uff0c\u6c42\u81fb\u533b\u5b66\u4e0eIDT\u7b7e\u7f72\u80bf\u7624\u5927Panel\u7684\u6218\u7565\u5408\u4f5c\u534f\u8bae\u3002<\/div>\n
\u6b64\u524dFDA\u6279\u51c6\u7684\u5927Panel\u5305\u62ec\uff1a<\/div>\n\n
\n
\"RmFicvQBAkgC6W96mrfXPjJ2LlBjWj9Nmib4EcKiaicrI8rOj2u3d56gZhcUWsmgbSibsPu83OMmdDmvSav2qpT9kNw\"\/<\/figure><\/div>\n\n
\u56fe\uff1aFDA\u6279\u51c6\u5927Panel<\/div>\n
\uff08\u6765\u6e90\/FDA\uff0c\u57fa\u56e0\u6167\u6574\u7406\uff09<\/div>\n
\u6cdb\u764c\u79cdNGS\u8bca\u65ad\u7684\u843d\u5b50\u70b9\u662f\u6cdb\u764c\u79cd\u9776\u5411\u836f\uff08\u6216\u79f0\u5e7f\u8c31\u6297\u764c\u836f\uff09\u548c\u80bf\u7624\u7b5b\u67e5\u3002\u76ee\u524dFDA\u6279\u51c6\u7684\u5e7f\u8c31\u6297\u764c\u836f\u5305\u62ec\uff1a2017\u5e745\u6708\u6279\u51c6\u7684Keytruda\uff0c\u7528\u4e8e\u6cbb\u7597\u5e26\u6709\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\u9ad8\uff08MSI-H\uff09\u6216\u9519\u914d\u4fee\u590d\u7f3a\u9677\uff08dMMR\uff09\u7684\u4e0d\u53ef\u5207\u9664\u6216\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\uff1b2018\u5e7411\u6708\u30012019\u5e748\u6708\u5206\u522b\u6279\u51c6\u7684Vitrakvi\uff08larotrectinib\uff0c\u62c9\u7f57\u66ff\u5c3c\uff09\u3001Entrectinib\uff08Rozlytrek\uff0c\u6069\u66f2\u66ff\u5c3c\uff09\uff0c\u7528\u4e8e\u6cbb\u7597\u643a\u5e26NTRK\u57fa\u56e0\u878d\u5408\u7684\u5b9e\u4f53\u7624\u60a3\u8005\u3002<\/div>\n
\u00a0<\/div>\n
2\uff09\u7532\u57fa\u5316<\/div>\n
\u8fd1\u5e74\uff0c\u7532\u57fa\u5316\u4e0e\u8868\u89c2\u9057\u4f20\u5b66\u7684\u7814\u7a76\u7684\u8fdb\u5c55\uff0c\u6b63\u52a0\u901f\u7532\u57fa\u5316\u68c0\u6d4b\u8bd5\u5242\u76d2\u7684\u4e0a\u5e02\u30022020\u5e744\u6708\uff0cNMPA\u6279\u51c6\u4e86\u535a\u5c14\u8bda(\u5317\u4eac)\u79d1\u6280\u6709\u9650\u516c\u53f8\u7684\u201cRNF180\/Septin9\u57fa\u56e0\u7532\u57fa\u5316\u68c0\u6d4b\u8bd5\u5242\u76d2(PCR\u8367\u5149\u63a2\u9488\u6cd5)\u201d\u3002<\/div>\n
2020 AACR\u4f1a\u8bae\u4e0a\uff0c\u65af\u5766\u798f\u5927\u5b66Mohammad Esfahani\u7684\u7814\u7a76\u56e2\u961f\u5c55\u793a\u4e86EPIC-Seq\u6280\u672f\uff0c\u53ca\u5229\u7528cfDNA\u7247\u6bb5\u5316\u6a21\u5f0f\u8fdb\u884c\u764c\u75c7\u68c0\u6d4b\u548c\u4e9a\u578b\u5206\u578b\u30027\u670821\u65e5\uff0c\u590d\u65e6\u5927\u5b66\u4e0e\u9e4d\u8fdc\u57fa\u56e0\u7814\u7a76\u56e2\u961f\u5728Nature Communication\u53d1\u8868\u7814\u7a76\u6210\u679c\u663e\u793a\uff1a\u57fa\u4e8ectDNA\u7532\u57fa\u5316\u6cdb\u764c\u7b5b\u67e5\u6280\u672f\u7684PanSeer\u65b9\u6cd5\u53ef\u4ee5\u6bd4\u5e38\u89c4\u8bca\u65ad\u63d0\u524d\u56db\u5e74\u53d1\u73b0\u764c\u75c7\u3002<\/div>\n
\u00a0<\/div>\n
3\uff09\u7eb3\u7c73\u5b54\u6d4b\u5e8f<\/div>\n
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\u52a0\u901f\u53d1\u5c55\u671f\u662f2017\u5e74\uff08\u8fdb\u5165\u4e2d\u56fd\u5e02\u573a\uff09\u548c2018\u5e74\uff08\u53d1\u5e03\u9ad8\u901a\u91cf\u6d4b\u5e8f\u8bbe\u5907PromethION\uff09\uff0c\u7d2f\u8ba1\u83b7\u5f977.15\u4ebf\u82f1\u9551\u7684\u6295\u8d44\uff0c\u6295\u8d44\u8005\u5305\u62ec\u836f\u4f01\u5b89\u8fdb\u3001\u5efa\u8bbe\u94f6\u884c\uff08\u56fd\u9645\uff09\u3001\u65b0\u52a0\u5761\u653f\u5e9c\u6295\u8d44\u516c\u53f8 (GIC)\u3001\u6fb3\u5927\u5229\u4e9a\u517b\u8001\u57fa\u91d1Hostplus\uff0c\u636e\u5916\u5a92\u6210\u817e\u8baf\u8ba1\u5212\u6536\u8d2d\u5176\u90e8\u5206\u80a1\u4efd\u3002<\/div>\n
\u00a0<\/div>\n
2020\u5e74ONT\u5f97\u5230\u98de\u8dc3\u5f0f\u53d1\u5c55\uff1a<\/div>\n
\u79d1\u7814\u4e0a\uff0cUCSC\u7684Kishwar Shafin\u5728Nature Biotechnology \u53d1\u8868\u6210\u679c\uff0c\u901a\u8fc7PromethION\u548cShasta\u7ec4\u88c5\u5668\uff0c\u57286\u5c0f\u65f6\u5185\u4ec5\u4f7f\u7528\u7eb3\u7c73\u5b54\u5e8f\u5217\u5b8c\u6210\u4e86\u5b8c\u6574\u7684\u5355\u500d\u4f53\u4eba\u7c7b\u57fa\u56e0\u7ec4\u7ec4\u88c5\uff0c\u82b1\u8d39\u4ec5$70\uff0c\u77eb\u6b63\u540e\u7684\u5355\u500d\u4f53\u7ec4\u88c5\u4e00\u81f4\u6027\u8d85\u8fc799.9\uff05\uff08Phred\u8d28\u91cf\u5f97\u5206QV = 30\uff09\uff0c9 \u5929\u5185\u4ece\u5934\u7ec4\u88c5\u4e8611\u4e2a\u9ad8\u5ea6\u8fde\u7eed\u7684\u4eba\u7c7b\u57fa\u56e0\u7ec4\uff0c\u83b7\u5f972.3Tb\u6d4b\u5e8f\u6570\u636e\uff0c\u5e73\u5747\u8986\u76d6\u6df1\u5ea6\u7ea663X\uff0cN50\u4e3a42 kb\uff0c\u5176\u4e2d\u5bf9\u8d85\u8fc7100 kb\u7684\u8d85\u957f\u8bfb\u957f\u7684\u8986\u76d6\u5ea6\u7ea66.5X\uff1b<\/div>\n
\u00a0<\/div>\n
\u4ea7\u54c1\u4e0a\uff0cONT\u9488\u5bf9\u5f15\u53d1\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u80ba\u708e\uff08COVID-19\uff09\u7684SARS-CoV-2\u75c5\u6bd2\u5f00\u53d1\u7684\u65b0\u4e00\u4ee3\u7aef\u5230\u7aef\u5206\u6790\u6cd5\u5df2\u8fdb\u5165\u540e\u671f\u9636\u6bb5\uff1b<\/div>\n
\u00a0<\/div>\n
\u5e94\u7528\u4e0a\uff0c\u6b66\u6c49\u5927\u5b66\u8054\u5408\u56e2\u961f\u57fa\u4e8eONT\u5e73\u53f0\u5f00\u53d1\u7eb3\u7c73\u5b54\u9776\u5411\u6d4b\u5e8f\u6cd5\uff0c\u6d4b\u5e8f\u540e4\u5c0f\u65f6\u5185\u9ad8\u654f\u611f\u6027\u3001\u9ad8\u51c6\u786e\u6027\u540c\u65f6\u68c0\u6d4bSARS-CoV-2\u548c\u5176\u4ed610\u5927\u7c7b\u53ca40\u4f59\u79cd\u547c\u5438\u9053\u75c5\u6bd2\uff0c\u5176\u6700\u4f4e\u68c0\u6d4b\u9650\u9ad8\u4e8e\u76ee\u524d\u5e7f\u6cdb\u4f7f\u7528\u7684qPCR\u7684100\u500d\u3002\u65b0\u51a0\u671f\u95f4\uff0c\u8d85\u8fc7200\u53f0MinION\u638c\u4e0a\u6d4b\u5e8f\u4eea\u5728\u4e2d\u56fd\u5f97\u5230\u5b89\u88c5\uff1b<\/div>\n
\u00a0<\/div>\n
\u5e02\u573a\u4e0a\uff0c3\u6708\uff0c\u8fbe\u745e\u751f\u7269\u5ba3\u5e03\u4f9d\u6258MinION\u5e73\u53f0\uff0c\u5f00\u53d1\u4e86\u5feb\u901f\u9ad8\u7075\u654f SARS-CoV-2\u7eb3\u7c73\u5b54\u9776\u5411\u6d4b\u5e8f\u8bd5\u5242\u76d2\uff1b5\u6708\uff0cONT\u5ba3\u5e03\u83b7\u5f974840\u4e07\u82f1\u9551\uff085920\u4e07\u7f8e\u91d1\uff09\u7684\u65b0\u4e00\u8f6e\u6295\u8d44\uff1b6\u6708\uff0c\u5148\u58f0\u8bca\u65ad\u57fa\u4e8eOxford Nanopore\u53f0\u5f0fGridION\u8bbe\u5907\u6269\u5c55\u5feb\u901f\u5b8f\u57fa\u56e0\u7ec4\u5e73\u53f0\u3002<\/div>\n
\u00a0<\/div>\n
\u9664\u4e86\u805a\u5149\u706f\u4e0b\u7684ONT\uff0c\u503c\u5f97\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u516c\u53f8\u5305\u62ecStratos Genomics\u516c\u53f8\u3001\u9f50\u78b3\u79d1\u6280\u7b49\u30022020\u5e745\u6708\uff0c\u7f57\u6c0f\u5ba3\u5e03\u5df2\u6536\u8d2d\u521d\u521b\u6d4b\u5e8f\u6280\u672f\u516c\u53f8Stratos Genomics\u516c\u53f8\uff0c\u4ee5\u63a8\u8fdb\u7f57\u6c0f\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u4eea\u7684\u5f00\u53d1\uff0c\u9762\u5411\u5feb\u901f\u3001\u7075\u6d3b\u548c\u7ecf\u6d4e\u9ad8\u6548\u7684\u4e34\u5e8a\u8bca\u65ad\u68c0\u6d4b\u3002<\/div>\n
\u7531\u6765\u81eaUCLA\u3001UIUC\u3001\u6e05\u534e\u5927\u5b66\u7684\u5b66\u9738\u521b\u59cb\u5efa\u7acb\u7684\u9f50\u78b3\u79d1\u6280\u4e8e2020\u5e745\u6708\u83b7\u8d851\u4ebf\u5143\u878d\u8d44\u3002\u9f50\u78b3\u79d1\u6280\u8054\u5408\u521b\u59cb\u4eba\u8c22\u4e39\u6559\u6388\u544a\u8bc9\u57fa\u56e0\u6167\uff0c\u672a\u6765\u4e00\u5e74\u9884\u8ba1\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u6280\u672f\u8fd8\u4f1a\u8fdb\u4e00\u6b65\u5feb\u901f\u6210\u957f\uff0c\u5176\u4e0b\u6e38\u79d1\u7814\u548c\u5e94\u7528\u4f1a\u5448\u73b0\u52a0\u901f\u53d1\u5c55\u7684\u6001\u52bf\u3002\u6211\u56fd\u6709\u671b\u63a8\u51fa\u5168\u56fd\u4ea7\u7684\uff0c\u5177\u6709\u5b8c\u5168\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u7684\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u8bbe\u5907\uff0c\u6253\u7834\u56fd\u5916\u4f01\u4e1a\u7684\u6280\u672f\u5784\u65ad\u3002<\/div>\n
\u00a0<\/div>\n
4\uff09TMB\u8bd5\u5242\u76d2<\/div>\n
2020\u5e74TMB\u8fdb\u5165\u4ea7\u54c1\u4e0a\u5e02\u9636\u6bb5\u30025\u6708\uff0cTMB\u5728\u83b7\u5f97FDA\u7684IVD\u6807\u5fd7\u7269\u6279\u51c6\u4e4b\u540e\uff0c\u9996\u6b21\u83b7\u5f97FDA\u4f34\u968f\u8bca\u65ad\u83b7\u6279\uff08Keytruda\u6cbb\u7597\u9ad8\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\uff08TMB-H\uff09\u4e14\u65e2\u5f80\u6cbb\u7597\u540e\u75be\u75c5\u8fdb\u5c55\u7684\u65e0\u6cd5\u5207\u9664\u6216\u8f6c\u79fb\u6027\u5b9e\u4f53\u7624\u60a3\u8005\uff0cF1CDX\u4e3a\u672c\u6b21\u5171\u540c\u83b7\u6279\u7684\u4f34\u968f\u8bca\u65ad\u68c0\u6d4b\u65b9\u6cd5\uff09\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u4e16\u548c\u57fa\u56e0\u7684\u201c\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7ec4\u7ec7TMB\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08\u53ef\u9006\u672b\u7aef\u7ec8\u6b62\u6d4b\u5e8f\u6cd5\uff09\u201d\u8fdb\u5165\u4e86NMPA\u7684\u521b\u65b0\u533b\u7597\u5668\u68b0\u7279\u522b\u5ba1\u67e5\u7a0b\u5e8f\u3002<\/div>\n
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5\uff09\u57fa\u56e0\u6cbb\u7597<\/div>\n\n
\n
\"RmFicvQBAkgCjyNQqZKzYk3iafoJvsaiaIF3K7NXeUb5XibYDjyHHNvrN0Pgxe1I5j1eou1TGhNc2yXWsEDsFpKhlg\"\/<\/figure><\/div>\n\n
\u56fe\uff1aFDA\u6279\u51c6\u7684\u7ec6\u80de\u6cbb\u7597\u548c\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1<\/div>\n
\uff08\u6765\u6e90\/FDA\u5b98\u7f51 \uff0c\u57fa\u56e0\u6167\u6574\u7406\uff09<\/div>\n
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3\u6708\uff0cEditas Medicine\u548cAllergan\u5ba3\u5e03\u9488\u5bf9Leber\u5148\u5929\u6027\u9ed1\u672610\uff08LCA10\uff09\u7684CRISPR\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u5728\u7814\u7597\u6cd5AGN-151587\uff08EDIT-101\uff09\uff0c\u5b8c\u6210\u4e86\u4f53\u5185CRISPR\u4e34\u5e8a\u8bd5\u9a8c\u5b8c\u6210\u7b2c\u4e00\u4f8b\u60a3\u8005\u7ed9\u836f\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
2017\u5e74-2018\u5e74\u95f4\uff0c\u7ebd\u798f\u65af\u521b\u59cb\u4eba\u3001\u539f\u534e\u4e2d\u79d1\u6280\u5927\u5b66\u540c\u6d4e\u533b\u5b66\u9662\u773c\u79d1\u4e3b\u4efb\u533b\u5e08\u674e\u658c\u6559\u6388\u5728\u4e2d\u56fd\u548c\u963f\u6839\u5ef7\u5b8c\u6210\u4e86\u5305\u62ec159\u540dLeber\u2019s\u9057\u4f20\u6027\u89c6\u795e\u7ecf\u75c5\u53d8\u60a3\u8005\u7684\u56fd\u9645\u6027\u57fa\u56e0\u6cbb\u7597\u4e34\u5e8a\u8bd5\u9a8c\uff08NCT03153293\uff09\u3002\u5728ASGCT 2020\u4f1a\u8bae\u4e2d\uff0c\u7ebd\u798f\u65afCEO\u9646\u82f1\u660e\u535a\u58eb\u4ee5\u53e3\u5934\u62a5\u544a\u5f62\u5f0f\u516c\u5e03\u4e86\u4e50\u89c2\u8fdb\u5c55\uff1b<\/div>\n
\u00a0<\/div>\n
7\u6708\uff0c\u4e0a\u6d77\u90a6\u8000\u751f\u7269\u4e0e\u4e2d\u5357\u5927\u5b66\u6e58\u96c5\u533b\u9662\u5408\u4f5c\u5f00\u5c55\u7684\u91cd\u5ea6\u5730\u8d2b\u4e34\u5e8a\u7814\u7a76\u53d6\u5f97\u91cd\u5927\u8fdb\u5c55\uff0c\u636e\u62a5\u9053\u6210\uff0c\u8fd9\u662f\u4e9a\u6d32\u9996\u6b21\u901a\u8fc7\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u6cbb\u7597\u5730\u8d2b\uff0c\u4e5f\u662f\u5168\u4e16\u754c\u9996\u6b21\u6210\u529f\u901a\u8fc7CRISPR\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u6cbb\u7597\u03b20\/\u03b20\u578b\u91cd\u5ea6\u5730\u8d2b\u3002<\/div>\n
6\uff09\u7ec6\u80de\u6cbb\u7597<\/div>\n
\u7ec6\u80de\u6cbb\u7597\u83b7\u5f97CDE\u653f\u7b56\u4ee5\u53ca\u4e8c\u7ea7\u5e02\u573a\u7684\u8ba4\u53ef\uff0c\u5c24\u5176\u662f\u57fa\u4e8e\u7ec6\u80de\u514d\u75ab\u6cbb\u7597\u7684\u65b0\u836f\u7814\u53d1\u3002<\/div>\n
\u7ec6\u80de\u6cbb\u7597\u516c\u53f8\u4f20\u5947\u751f\u7269\u4e0a\u5e02\uff0c\u52df\u8d44\u8d853\u4ebf\u7f8e\u5143\uff1b\u7ec6\u80de\u514d\u75ab\u6cbb\u7597\u7684\u6c38\u6cf0\u751f\u7269\u5728\u9999\u6e2f\u8054\u5408\u4ea4\u6613\u6240\u4e3b\u677f\u6302\u724c\u4e0a\u5e02\uff0c\u52df\u8d4411\u4ebf\u5143\uff1b<\/div>\n
\u00a0<\/div>\n
6\u6708\uff0c\u7ee7\u4fe1\u8fbe\u751f\u7269\u4e0e\u793c\u6765\u8fbe\u6210\u4e24\u6b21\u603b\u91d1\u989d\u8d85\u8fc715\u4ebf\u7f8e\u5143\u7684\u5168\u9762\u5408\u4f5c\u4e4b\u540e\uff0c\u4fe1\u8fbe\u751f\u7269\u5236\u836f\uff0801801.HK\uff09\u5ba3\u5e03\u4e0e\u7f57\u6c0f\u96c6\u56e2\u8fbe\u6210\u8fd120\u4ebf\u7f8e\u5143\u7814\u53d1\u6218\u7565\u5408\u4f5c\uff0c\u805a\u7126\u4e8e\u7528\u4e8e\u8840\u6db2\u80bf\u7624\u548c\u5b9e\u4f53\u80bf\u7624\u6cbb\u7597\u7684\u591a\u4e2a\u53cc\u7279\u5f02\u6027\u6297\u4f53\u3001\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u7814\u53d1\u548c\u5546\u54c1\u5316\uff1b<\/div>\n
7\u6708\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u53d1\u5e03\u300a\u514d\u75ab\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u4e34\u5e8a\u8bd5\u9a8c\u6280\u672f\u6307\u5bfc\u539f\u5219\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b\u3002\u8be5\u300a\u539f\u5219\u300b\u662f\u56fd\u5bb6\u836f\u76d1\u5c40\u4e2d\u56fd\u836f\u54c1\u76d1\u7ba1\u79d1\u5b66\u884c\u52a8\u8ba1\u5212\u9996\u6279\u7814\u7a76\u9879\u76ee\u4e4b\u4e00\u3002<\/div>\n
\u00a0<\/div>\n
3. \u5927\u6570\u636e\u8d4b\u80fd\u4ea7\u54c1\u5316\u8fdb\u7a0b<\/div>\n
\u5927\u6570\u636e\u5bf9\u4ea7\u54c1\u7684\u8d4b\u80fd\uff0c\u5305\u62ec\u57fa\u4e8e\u4eba\u53e3\u961f\u5217\u7684\u7814\u7a76\u6210\u679c\uff0c\u591a\u7ec4\u5b66\u4e0e\u8868\u578b\u7684\u7ed3\u5408\uff0c\u56fd\u4ea7\u5316\u533b\u7597\u5668\u68b0\u548c\u56fd\u5185\u6837\u672c\u5e02\u573a\u7684\u7ea2\u5229\uff0c\u4ee5\u53ca\u534a\u5bfc\u4f53\u3001IT\u4e0eBT\u4ea7\u4e1a\u7684\u878d\u5408\u3002\u8fd9\u91cc\u7565\u4f5c\u4e8b\u4f8b\u7b80\u8ff0\uff0c\u66f4\u591a\u8bc4\u8bba\u53ca\u5ef6\u4f38\u89c1\u57fa\u56e0\u6167\u76f8\u5173\u884c\u7814\u62a5\u544a\u3002<\/div>\n
2020\u5e748\u67085\u65e5\uff0c\u5168\u7403\u79c1\u52df\u57fa\u91d1\u5de8\u5934\u9ed1\u77f3\u5ba3\u5e03\u5df2\u6536\u8d2d\u57fa\u56e0\u65cf\u8c31\u7f51\u7ad9Ancestry.com\uff08Ancestry\uff09\uff0c\u4ea4\u6613\u603b\u4ef7\u4e3a47\u4ebf\u7f8e\u5143\uff08\u7ea6\u5408\u4eba\u6c11\u5e01326\u4ebf\u5143\uff09\uff0c\u521b\u4e0b\u9ed1\u77f3\u5355\u7b14\u6536\u8d2d\u6848\u7684\u91d1\u989d\u7eaa\u5f55\u3002\u901a\u8fc7\u6295\u8d44\uff0c\u9ed1\u77f3\u8868\u793a\u5e0c\u671b\u5728Ancestry\u5e73\u53f0\u4e0a\u79ef\u7d2f\u66f4\u591a\u6570\u636e\uff0c\u5e76\u8fdb\u884c\u66f4\u5177\u521b\u65b0\u6027\u7684\u4ea7\u54c1\u529f\u80fd\u5f00\u53d1\uff0c\u4ee5\u7ee7\u7eed\u4e3a\u5e02\u573a\u63d0\u4f9b\u5dee\u5f02\u5316\u670d\u52a1\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
\u5b81\u5149\u9662\u58eb\u56e2\u961f\u9886\u8854\u4e2d\u56fd\u4ee3\u8c22\u89e3\u6790\u8ba1\u5212ChinaMAP\uff0c\u5728Cell Research\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u9996\u6b21\u62a5\u9053\u4e86ChinaMAP\u4e00\u671f\u7814\u7a76\u5bf9\u8986\u76d6\u5168\u56fd27\u4e2a\u7701\u4efd\u548c\u76f4\u8f96\u5e02\u30018\u4e2a\u6c11\u65cf\u300110588\u4eba\u7684\u9ad8\u6df1\u5ea6\uff0840X\uff09\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6570\u636e\u548c\u8868\u578b\u7684\u7cfb\u7edf\u6027\u5206\u6790\u3002\u901a\u8fc7\u5efa\u7acb\u9ad8\u8d28\u91cf\u4e2d\u56fd\u4eba\u7fa4\u57fa\u56e0\u6570\u636e\u5e93\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
\u901a\u8fc7\u6784\u5efa\u65e0gap\u7684\u67d3\u8272\u4f53\u7ea7\u522b\u57fa\u56e0\u7ec4\uff0c\u5e76\u7ed3\u5408\u8f6c\u5f55\u7ec4\u3001\u6838\u7cd6\u4f53RNA\u7b49\u591a\u7ef4\u6570\u636e\u8fdb\u884c\u591a\u91cd\u7cfb\u7edf\u53d1\u80b2\u5206\u6790\u53ca\u6bd4\u8f83\u57fa\u56e0\u7ec4\u5b66\u5206\u6790\uff0c\u786e\u5b9a\u4e86\u8be5\u7269\u79cd\u5c5e\u4e8e\u7eff\u8272\u690d\u7269\u5f53\u4e2d\u6700\u65e9\u5206\u5316\u51fa\u6765\u7684\u5206\u652f\u95e8\u7c7b\u2014\u2014\u534e\u85fb\u95e8\uff08Prasinodermaphyta\uff09\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
\u7f57\u6c0f\uff08Roche\uff09\u5ba3\u5e03\u63a8\u51fa\u83b7\u6b27\u76dfCE-IVD\u8ba4\u8bc1\u7684\u81ea\u52a8\u5316\u6570\u5b57\u75c5\u7406\u7b97\u6cd5uPath PD-L1\uff08SP263\uff09\uff0c\u7528\u4e8e\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u56fe\u50cf\u5206\u6790\u3002\u8be5\u7b97\u6cd5\u80fd\u63d0\u9ad8\u80ba\u764c\u8bca\u65ad\u7684\u901f\u5ea6\u548c\u51c6\u786e\u6027\uff0c\u4e3a\u60a3\u8005\u63d0\u4f9b\u6709\u9488\u5bf9\u6027\u7684\u6cbb\u7597\u65b9\u6848\u3002<\/div>\n
\u00a0<\/div>\n
4. \u8054\u5408\u5f00\u53d1\u4ea7\u54c1\u7684\u6a21\u5f0f<\/div>\n
\u4ece\u4f34\u968f\u8bca\u65ad\u3001\u9057\u4f20\u75c5\u57fa\u56e0\u6cbb\u7597\u3001DTC\u57fa\u56e0\u68c0\u6d4b\u53ca\u884d\u751f\u4ea7\u54c1\u7b49\uff0c\u57fa\u56e0\u4ea7\u54c1\u5f00\u53d1\u7684\u590d\u6742\u5ea6\u548c\u5546\u54c1\u5316\uff0c\u9700\u8981\u591a\u5b66\u79d1\u3001\u8de8\u4ea7\u4e1a\u7684\u534f\u4f5c\u3002\u5176\u4e2d\uff0c\u6700\u4e3a\u5178\u578b\u7684\u662f\u4f34\u968f\u8bca\u65ad\u4e0e\u65b0\u836f\u53d1\u73b0\u3001\u4e34\u5e8a\u8bd5\u9a8c\u5165\u7ec4\u3001\u5e02\u573a\u63a8\u5e7f\u7684\u6df1\u5ea6\u5408\u4f5c\u3002\u4e3e\u4f8b\u5982\u4e0b\uff1a<\/div>\n
\u71c3\u77f3\u533b\u5b66\u5ba3\u5e03\u4e0e\u57fa\u77f3\u836f\u4e1a\u8fbe\u6210\u4f34\u968f\u8bca\u65ad\uff08CDx\uff09\u6218\u7565\u5408\u4f5c\uff0c\u53cc\u65b9\u5c06\u5f00\u53d1\u548c\u5546\u4e1a\u5316Pralsetinib\uff1b<\/div>\n
\u00a0<\/div>\n
\u590d\u5b8f\u6c49\u9716\uff082696.HK\uff09\u4e0e\u57fa\u51c6\u533b\u7597\u8fbe\u6210\u6218\u7565\u5408\u4f5c\u534f\u8bae\uff0c\u53cc\u65b9\u5c06\u5171\u540c\u5f00\u53d1\u80c3\u764cHER2\u57fa\u56e0\u6269\u589e\u6db2\u4f53\u6d3b\u68c0\u4f34\u968f\u8bca\u65ad\u4ea7\u54c1\uff0c\u7528\u4e8e\u68c0\u6d4b\u8840\u6db2\u6837\u54c1\u4e2dHER2\u57fa\u56e0\u6269\u589e\u5e76\u5728\u80c3\u764c\u60a3\u8005\u4e2d\u8fdb\u884c\u9a8c\u8bc1\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
\u62dc\u8033\u516c\u53f8\u4e0e\u81f3\u672c\u533b\u7597\u79d1\u6280\u8fbe\u6210\u5408\u4f5c\uff0c\u5728\u4e2d\u56fd\u5e02\u573a\u5f00\u53d1\u57fa\u4e8e\u4e8c\u4ee3\u6d4b\u5e8f\uff08NGS\uff09\u6280\u672f\u7684\u7528\u4e8eNTRK\u878d\u5408\u57fa\u56e0\u68c0\u6d4b\u7684\u4f34\u968f\u8bca\u65ad-\u4f53\u5916\u8bca\u65ad\u8bd5\u5242\uff08CDx-IVD\uff09\u4ea7\u54c1\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
\u827e\u5fb7\u751f\u7269\u5ba3\u5e03\u4e0e\u5f3a\u751f\u8fbe\u6210\u4f34\u968f\u8bca\u65ad\u6218\u7565\u5408\u4f5c\uff0c\u57fa\u4e8e\u827e\u5fb7\u751f\u7269\u7684NGS\u6280\u672f\u5e73\u53f0\uff0c\u63a8\u8fdb\u7ef4\u60e0\u5065\u00ae\u7684\u53d8\u66f4\u6ce8\u518c\uff0c\u6269\u5927\u4f34\u968f\u8bca\u65ad\u8303\u56f4\uff1b<\/div>\n
\u00a0<\/div>\n
Humana\u5ba3\u5e03\u4e0e\u6c83\u5c14\u739b\uff0cQuest Diagnostics\u548cPWNHealth\u7684\u5408\u4f5c\uff0c\u4e3a\u8ba1\u5212\u6210\u5458\u5728\u5168\u56fd\u7684\u90e8\u5206\u6c83\u5c14\u739b\u90bb\u91cc\u5e02\u573a\u76f4\u901a\u836f\u623f\u63d0\u4f9b\u51a0\u72b6\u75c5\u6bd2\u514d\u4e0b\u8f66\uff08drive-thru\uff09\u68c0\u6d4b\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
\u534e\u5927\u57fa\u56e0\u5ba3\u5e03\u548c\u4f55\u6c0f\u773c\u79d1\u5c06\u8054\u624b\u5728\u201c\u9057\u4f20\u6027\u89c6\u7f51\u819c\u75be\u75c5\u57fa\u56e0\u6cbb\u7597\u201d\u65b9\u9762\u5c55\u5f00\u6df1\u5ea6\u5408\u4f5c\uff0c\u5171\u5efa\u5f00\u653e\u6027\u7684\u56fd\u5bb6\u57fa\u56e0\u5e93\u7684\u773c\u57fa\u56e0\u5e93\u57fa\u56e0\u7f16\u8f91\u5e73\u53f0\u3002<\/div>\n
\u00a0<\/div>\n
\u56db\u3001\u65b0\u5174\u6280\u672f\u7684\u673a\u4f1a<\/div>\n
\u57fa\u56e0\u6167\u8ba4\u4e3a\uff0c\u672a\u6765\u65b0\u5174\u6280\u672f\u7684\u521b\u65b0\u5f00\u53d1\u548c\u4ea7\u4e1a\u5316\u673a\u4f1a\u5305\u62ec\uff1a<\/div>\n
1. mNGS\u6d4b\u5e8f<\/div>\n
\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u534e\u5c71\u533b\u9662\u5f20\u6587\u5b8f\u6559\u6388\u56e2\u961f\u5728Ann Transl Med\u520a\u6587\uff0c\u53d1\u73b0mNGS\u5728\u5e38\u89c4\u5fae\u751f\u7269\u68c0\u6d4b\u9634\u6027\u60a3\u8005\u7684\u6297\u751f\u7d20\u5e94\u7528\u4e2d\u53d1\u6325\u4e86\u91cd\u8981\u4f5c\u7528\uff0c\u57fa\u4e8emNGS\u68c0\u6d4b\u7ed3\u679c\u8c03\u6574\u6297\u751f\u7d20\u65b9\u6848\u7684\u60a3\u8005\u7684\u6cbb\u7597\u6210\u529f\u7387\uff0881.8%\uff09\u663e\u8457\u9ad8\u4e8e\u4f7f\u7528\u7ecf\u9a8c\u6027\u6297\u751f\u7d20\u7684\u60a3\u8005\uff0852.6%\uff09\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
\u4e0a\u6d77\u9510\u7fcc\u751f\u7269\u3001\u91d1\u5319\u57fa\u56e0\u3001\u4e88\u679c\u751f\u7269\u5b8c\u6210\u65b0\u4e00\u8f6e\u878d\u8d44\u3002<\/div>\n
\u00a0<\/div>\n
2. BDA\u6280\u672f<\/div>\n
\u8be5\u6280\u672f\u5c06Nanopore\u9488\u5bf9\u5c0f\u7247\u6bb5DNA\u7684\u6709\u6548\u6d4b\u5e8f\u901a\u91cf\u63d0\u9ad8\u4e8610\u500d\u3002Oxford Nanopore\u6280\u672f\u516c\u53f8\u4ee5\u672a\u516c\u5f00\u7684\u652f\u4ed8\u4ef7\u683c\u5728\u5168\u7403\u83b7\u5f97\u9605\u5c14\u57fa\u56e0\u7684BDA\u6280\u672f\uff08\u6291\u5236\u63a2\u9488\u7f6e\u6362\u6269\u589e\u6280\u672f\uff09\u6388\u6743\u8bb8\u53ef\u3002<\/div>\n
\u00a0<\/div>\n
3. \u751f\u80b2\u5065\u5eb7\u65b9\u9762\uff08\u8f85\u52a9\u751f\u6b96\u3001\u643a\u5e26\u8005\u7b5b\u67e5\u3001NIPT Plus\uff09<\/div>\n
2\u6708\uff0cNMPA\u6279\u51c6\u8d1d\u5eb7\u533b\u7597\u80da\u80ce\u690d\u5165\u524d\u67d3\u8272\u4f53\u975e\u6574\u500d\u4f53\u68c0\u6d4b\u8bd5\u5242\u76d2\u4e0a\u5e02\uff1b\u00a0<\/div>\n
3\u6708\uff0c\u4e2d\u5357\u5927\u5b66\u751f\u547d\u79d1\u5b66\u5b66\u9662\u533b\u5b66\u9057\u4f20\u5b66\u7814\u7a76\u4e2d\u5fc3\u3001\u8d1d\u52d2\u533b\u5b66\u9662\u548c\u8d1d\u745e\u57fa\u56e0\uff0c\u8fd110\u4e07\u4eba\u968f\u8bbf\u8bc1\u5b9eNIPT Plus\u53ef\u4f5c\u4e3a\u4ea7\u524d\u4e00\u7ea7\u7b5b\u67e5\u65b9\u6cd5\uff1b\u00a0<\/div>\n
4\u6708\uff0cACTA OBSTET GYN SCAN \u6742\u5fd7\u4e0a\u53d1\u8868\u4e86\u4e00\u7bc7\u9898\u4e3a\u300a\u4ee5\u751f\u6b96\u4e3a\u76ee\u7684\u7684\u56fd\u5bb6\u643a\u5e26\u8005\u7b5b\u67e5\u57fa\u56e0\u68c0\u6d4b\u9879\u76ee\u5e26\u6765\u7684\u5f71\u54cd\u300b\u7684\u5927\u6570\u636e\u6587\u7ae0\uff0c\u5c55\u793a\u4e86\u4ee5\u8272\u5217\u201c\u56fd\u5bb6\u643a\u5e26\u8005\u7b5b\u67e5\u57fa\u56e0\u68c0\u6d4b\u9879\u76ee\u201d\u5b9e\u65bd\u7684\u6570\u636e [1]\u30022015-2017\u5e74\uff0c\u8be5\u9879\u76ee\u5171\u5b8c\u6210\u4e8691\u4e07\u4f8b\u6269\u5c55\u6027\u643a\u5e26\u8005\u7b5b\u67e5 (Expanded Carrier Screening\uff0cECS)\uff0c\u5bf9\u751f\u6b96\u51b3\u7b56\u548c\u51fa\u751f\u7f3a\u9677\u9632\u63a7\u610f\u4e49\u6781\u5176\u91cd\u5927\u3002<\/div>\n
\u00a0<\/div>\n
4. \u5355\u7ec6\u80de\u6d4b\u5e8f<\/div>\n
1\uff09Broad\u5927\u725bAviv Regev\u51fa\u4efb\u7f57\u6c0f\u5b50\u516c\u53f8Genentech\u7814\u53d1\u8d1f\u8d23\u4eba\uff1b\u00a0<\/div>\n
2\uff093\u670825\u65e5\uff0c\u90ed\u56fd\u9aa5\u56e2\u961f\u4e0e\u6d59\u5927\u56e2\u961f\u5408\u4f5c\u7cfb\u7edf\u5730\u7ed8\u5236\u4e86\u8de8\u8d8a\u80da\u80ce\u548c\u6210\u5e74\u4e24\u4e2a\u65f6\u671f\uff0c\u6db5\u76d6\u516b\u5927\u7cfb\u7edf\u7684\u4eba\u7c7b\u7ec6\u80de\u56fe\u8c31\uff1b\u00a0<\/div>\n
3\uff09\u8c22\u6653\u4eae\u3001\u9ad8\u6b4c\u3001\u6c64\u5bcc\u916c\u4e54\u6770\u9662\u7b49\u57fa\u4e8e\u65b0\u5f00\u53d1\u7684\u5355\u7ec6\u80de\u6280\u672f\uff08MALBAC-DT\u548cMETATAC\uff09\uff0c\u7ed8\u5236\u4eba\u7c7b\u4e2d\u671f\u598a\u5a20\u80ce\u513f\u7ec4\u7ec7\u7ec6\u80de\u7684\u57fa\u56e0\u7ec4\u7ed3\u6784\u56fe\u8c31\uff1b<\/div>\n
4\uff096\u6708\uff0c\u5355\u7ec6\u80de\u5e73\u53f0\u4f01\u4e1a\u65b0\u683c\u5143\u53d1\u5e03\u81ea\u4e3b\u7814\u53d1\u7684\u4e00\u7ad9\u5f0f\u5355\u7ec6\u80de\u7cfb\u7edfSingleron\uff0c\u5bb8\u5b89\u751f\u7269\u5b8c\u62107000\u4e07\u5143B\u8f6e\u878d\u8d44\uff1b\u767e\u5965\u667a\u6c47\u83b7\u5f97IDG\u8d44\u672c\u7cfb\u5217\u878d\u8d44\uff1b<\/div>\n
5\uff09\u57fa\u56e0\u6167\u8054\u5408\u4f2f\u8c6a\u751f\u7269\u3001BD\u3001Illmina\u3001\u539a\u6cfd\u751f\u7269\u3001\u767e\u5965\u667a\u6c47\u53d1\u5e03\u5355\u7ec6\u80de\u884c\u7814\u62a5\u544a<\/a>\uff1b\u65e5\u7acb\uff08Hitachi\uff09\u8868\u793a\u5c06\u4e0eThinkCyte\u5408\u4f5c\u5f00\u53d1\u4eba\u5de5\u667a\u80fd\u9a71\u52a8\u7684\u7ec6\u80de\u5206\u6790\u548c\u5206\u9009\u7cfb\u7edf\u3002<\/div>\n
\u00a0<\/div>\n
5. \u65b0\u578b\u57fa\u56e0\u7f16\u8f91\u548c\u57fa\u56e0\u6cbb\u7597<\/div>\n
\u7ec6\u80de\u5916\u56ca\u6ce1ARMMS\u4f20\u8f93\u7684\u57fa\u56e0\u6cbb\u7597\uff1a7\u670822\u65e5\uff0c\u62dc\u8033\u548c\u6668\u5174\u8d44\u672c\u7275\u5934\u53d1\u8d77\u751f\u7269\u6280\u672f\u516c\u53f8Vesigen Therapeutics\u7684A\u8f6e\u6295\u8d44\uff0c\u91d1\u989d\u7ea62850\u4e07\u7f8e\u5143\u3002Vesigen Therapeutics\u6b63\u5728\u5f00\u53d1\u4e00\u79cd\u7279\u6b8a\u7c7b\u578b\u7684\u7ec6\u80de\u5916\u56ca\u6ce1ARMMS\uff08\u4f7f\u7528ARRDC1\u4ecb\u5bfc\u7684\u5fae\u56ca\u6ce1\uff09\u52a9\u529b\u751f\u7269\u836f\u7269\u8f93\u9001\uff1b\u00a0<\/div>\n
\u5355\u78b1\u57fa\u7f16\u8f91\u65b0\u5de5\u5177\u53ef\u5b9e\u73b0C-G\u53caC-A\u78b1\u57fa\u98a0\u6362\uff1b\u00a0<\/div>\n
\u7ebf\u7c92\u4f53DNA\u57fa\u56e0\u7f16\uff1aNature\u520a\u6587\uff0c\u5218\u5982\u8c26\uff08David Liu\uff09\u6559\u6388\u4e0e\u534e\u76db\u987f\u5927\u5b66\u5408\u4f5c\u7814\u7a76\u5f00\u53d1\u51fa\u201c\u7b2c\u4e00\u6b3e\u5b9e\u73b0\u7ebf\u7c92\u4f53DNA\u7cbe\u786e\u7f16\u8f91\u7684\u5206\u5b50\u5de5\u5177\u201d\uff1b\u00a0<\/div>\n
\u53ccAAV\u8f7d\u4f53\u9012\u9001\u5355\u78b1\u57fa\u7f16\u8f91\u5668\uff1aScience Translational Medicine \u520a\u6587\uff0c\u5218\u5982\u8c26\uff08David Liu\uff09\u56e2\u961f\u901a\u8fc7\u53ccAAV\u8f7d\u4f53\u9012\u9001\u5355\u78b1\u57fa\u7f16\u8f91\u5668\uff0c\u6062\u590d\u4e86Tmc1\u57fa\u56e0\u9690\u6027\u7a81\u53d8\u5bfc\u81f4\u7684\u5b8c\u5168\u8033\u804b\u5c0f\u9f20\u7684\u542c\u529b\uff1b<\/div>\n
\u53cc\u78b1\u57fa\u57fa\u56e0\u7f16\u8f91\u5668\uff1a\u534e\u4e1c\u5e08\u8303\u5927\u5b66\u674e\u5927\u529b\u8bfe\u9898\u7ec4\u5728Nature Biotechnology\u53d1\u8868\u53cc\u78b1\u57fa\u57fa\u56e0\u7f16\u8f91\u5668(hyCBE)\uff0c\u80fd\u9ad8\u6548\u5730\u540c\u65f6\u4ea7\u751f\u4e24\u79cd\u4e0d\u540c\u78b1\u57fa\u7684\u7a81\u53d8\uff08C>T\u548cA>G\u7684\u9ad8\u6548\u8f6c\u6362\uff09\u3002<\/div>\n
\u00a0<\/div>\n
6. \u5176\u4ed6<\/div>\n
\u975e\u7f16\u7801\u57fa\u56e0\uff1a\u5251\u6865\u5927\u5b66\u7814\u7a76\u56e2\u961f\u5728Nature\u53d1\u8868\u4e86\u4e00\u9879\u65b0\u7814\u7a76\uff0c\u4f7f\u7528\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\uff08WGS\uff09\u9274\u5b9a\u4e86\u56db\u79cd\u65b0\u7684\u975e\u7f16\u7801\u57fa\u56e0\u53d8\u5f02\uff0c\u5b83\u4eec\u901a\u8fc7\u7834\u574fARPC1B\u3001GATA1\u3001LRBA\u548cMPL\u7684\u8f6c\u5f55\u800c\u81f4\u75c5\uff1b\u8d39\u57ce\u513f\u7ae5\u533b\u9662\u5f00\u53d1\u51fa\u65b0\u578b\u7b97\u6cd5\uff0c\u53ef\u540c\u65f6\u8bc6\u522b5\u79cd\u513f\u7ae5\u764c\u75c7\u7c7b\u578b\u7684\u975e\u7f16\u7801\u7a81\u53d8\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
\u57fa\u56e0\u5408\u6210\uff1a\u4e2d\u56fd\u79d1\u5b66\u9662\u6df1\u5733\u5148\u8fdb\u6280\u672f\u7814\u7a76\u9662\u4f5c\u4e3a\u5efa\u8bbe\u7275\u5934\u201c\u5408\u6210\u751f\u7269\u7814\u7a76\u91cd\u5927\u79d1\u6280\u57fa\u7840\u8bbe\u65bd\u201d \u843d\u5730\u6df1\u5733\uff1b\u8054\u5ddd\u751f\u7269\u5b8c\u62101.15\u4ebf\u5143B\u8f6e\u878d\u8d44\uff0c\u7528\u4e8e\u81ea\u4e3b\u57fa\u56e0\u6355\u83b7\u5e73\u53f0\u53ca\u57fa\u56e0\u5408\u6210\u5e73\u53f0\u7684\u7814\u53d1\uff1b\u57fa\u56e0\u5408\u6210\u516c\u53f8Evonetix\u5b8c\u62103000\u4e07\u7f8e\u5143B\u8f6e\u878d\u8d44\uff1b<\/div>\n
\u00a0<\/div>\n
DNA\u5b58\u50a8\uff1a2020\u5e74\uff0cNature Communication\u520a\u6587\uff0c\u7f8e\u56fd\u5317\u5361\u7f57\u83b1\u7eb3\u5dde\u7acb\u5927\u5b66\u7814\u7a76\u8005\u5f00\u53d1\u4e86\u4e00\u79cd\u5168\u65b0\u7684DNA\u6570\u636e\u5b58\u50a8\u7cfb\u7edf\uff0c\u4e0d\u4f9d\u8d56\u4f20\u7edf\u805a\u5408\u9176\u94fe\u5f0f\u53cd\u5e94\uff08PCR\uff09\u64cd\u4f5c\uff0c\u5e38\u6e29\u8fd0\u4f5c\u66f4\u5177\u5b9e\u7528\u6027\uff0c\u800c\u4e14\u53ef\u4f7f\u7528\u6237\u5728\u4e0d\u7834\u574f\u539f\u59cb\u6587\u4ef6\u7684\u60c5\u51b5\u4e0b\u8bfb\u53d6\u6216\u4fee\u6539\u6570\u636e\u6587\u4ef6\uff1b2019\u5e74\uff0c\u534e\u4e3a\u5ba3\u5e03\u6295\u8d44DNA\u5b58\u50a8\u7814\u7a76\uff0c\u7a81\u7834\u6570\u636e\u5b58\u50a8\u5bb9\u91cf\u6781\u9650\uff1b\u65e9\u57282017\u5e74\uff0c\u5fae\u8f6f\u79f0\u548c\u534e\u76db\u987f\u5927\u5b66\u7814\u7a76\u4eba\u5458\u5408\u4f5c\uff0c\u5229\u7528\u4eba\u5de5\u5408\u6210DNA\u4f5c\u4e3a\u6570\u636e\u5b58\u50a8\u4ecb\u8d28\u4fdd\u5b58\u4e86\u5927\u7ea6200MB\u6570\u636e\u3002<\/div>\n
\u00a0<\/div>\n
\u4e94\u3001\u8d44\u672c\u5e76\u8d2d<\/div>\n
\u539f\u53ef\u80fd\u57282020\u5e74\u7206\u53d1\u7684\u5e76\u8d2d\u4e8b\u4ef6\uff0c\u56e0\u4e3a\u75ab\u60c5\u7684\u5f71\u54cd\u7a0d\u6709\u6401\u7f6e\uff08\u5934\u90e8\u516c\u53f8\u5f00\u59cb\u6ca1\u94b1\uff0c\u540e\u6765\u4e00\u65f6\u592a\u6709\u94b1\uff09\u3002\u9884\u8ba1\u57282021-2023\u5e74\u5f62\u6210\u4e00\u62e8\u517c\u5e76\u548c\u6536\u8d2d\u6d6a\u6f6e\u3002<\/div>\n
\u57fa\u56e0\u884c\u4e1a\u5177\u6709\u4ee3\u8868\u6027\u7684\u5e76\u8d2d\u6848\u4f8b\u5305\u62ec\uff1a<\/div>\n
1\uff09Illumina\u5e76\u8d2dSolexa\u6210\u529f\u4ece\u751f\u7269\u82af\u7247\u516c\u53f8\u8f6c\u578b\u6210\u4e3a\u6d4b\u5e8f\u9f99\u5934\uff1b<\/div>\n
2\uff09\u534e\u5927\u5e76\u8d2dComplete Genomics\u6210\u529f\u5b8c\u6210\u6d4b\u5e8f\u4eea\u56fd\u4ea7\u5316\u521d\u59cb\u5316\u5e76\u62d3\u5c55\u521b\u65b0\uff1b<\/div>\n
3\uff09Exact Sciences & Genomic Health\u7eb5\u5411\u8054\u5408\u653b\u5173\u764c\u75c7\uff1b<\/div>\n
4\uff09\u9605\u5c14\u57fa\u56e0 & NuProbe Global\u5408\u5e76\uff0c\u5c06\u5148\u8fdb\u7684\u5b9e\u9a8c\u5ba4\u6280\u672fBDA\u4e0e\u4e0d\u5b55\u4e0d\u80b2\u84dd\u6d77\u5e02\u573a\u7ed3\u5408\uff0c\u8d4b\u80fd\u4e0a\u6e38\u4f9b\u5e94\u94fe\u548c\u4e0b\u6e38IVD\u3002<\/div>\n\n
\n
\"RmFicvQBAkgC6W96mrfXPjJ2LlBjWj9NmVmut2poKic5grcvtmQlCdX4Mr6eic7Iv7GPSfrkVI7RB4XCUfljAn1JA\"\/<\/figure><\/div>\n\n
\u56fe\uff1a1996-2019\u5e74Quest\u53d1\u5c55\u8def\u5f84<\/div>\n
\uff08\u57fa\u56e0\u6167\u6574\u7406\uff09<\/div>\n
\u5e76\u8d2d\u7684\u6a21\u5f0f\u7b80\u5355\u5730\u8bb2\uff0c\u5305\u62ec\u7eb5\u5411\u5e76\u8d2d\uff08\u534f\u4f5c\uff09\u3001\u6a2a\u5411\u5e76\u8d2d\uff08\u6269\u5927\uff09\u548c\u591a\u5143\u5316\u7ecf\u8425\uff08\u4e1a\u52a1\u5347\u7ea7\uff09\u7b49\u3002\u5bf9\u4e8e\u57fa\u56e0\u53ca\u751f\u547d\u5065\u5eb7\u9886\u57df\uff0c\u5e76\u8d2d\u7684\u6a21\u5f0f\u5177\u4f53\u5305\u62ec\u54ea\u4e9b\uff1f\u5177\u6709\u6280\u672f\u548c\u6295\u8d44\u80cc\u666f\u7684\u7d2b\u725b\u57fa\u91d1\u6295\u8d44\u603b\u76d1\u4fde\u6ce2\uff0c\u66fe\u63a5\u53d7\u57fa\u56e0\u6167\u91c7\u8bbf\uff0c\u8c08\u5230\u6709\u5982\u4e0b\u51e0\u79cd\u60c5\u5f62\uff1a<\/div>\n
1\uff09\u4ea7\u54c1+\u670d\u52a1\u7684\u5ef6\u4f38\uff0c\u4f8b\u5982\u4f34\u968f\u8bca\u65ad\u548cPOCT\uff08point-of-care testing\uff0c\u5373\u65f6\u68c0\u9a8c\uff09\uff1b\u00a0<\/div>\n
2\uff09\u6e20\u9053+\u4ea7\u54c1\u7684\u7ec4\u5408\uff0c\u4f8b\u5982\u7b2c\u4e09\u65b9\u68c0\u9a8c\u8bca\u65ad\u548cPOCT\uff1b\u00a0<\/div>\n
3\uff09\u8bca\u65ad+\u6cbb\u7597\u7684\u4e00\u4f53\u5316\uff0c\u4f8b\u5982\u57fa\u56e0\u6cbb\u7597\u548c\u4f34\u968f\u8bca\u65ad\uff1b\u00a0<\/div>\n
3\uff09\u4ea7\u4e1a\u94fe\u4e0a\u4e0b\u6e38\u7684\u81ea\u7136\u6574\u5408\uff0c\u4f8b\u5982\u57fa\u56e0\u68c0\u6d4b\u7684\u4e0a\u4e2d\u4e0b\u6e38\u3002<\/div>\n\n
\n
\"RmFicvQBAkgC6W96mrfXPjJ2LlBjWj9NmQG2c0wYbKs5L0A1IuLibSZrEq3aGftXUibESLlwibd3iaVJv0icNEhYeJLw\"\/<\/figure><\/div>\n\n
\u56fe\uff1aIllumina\u8fd120\u5e74\u6210\u957f\u8def\u5f84<\/div>\n
\uff08\u57fa\u56e0\u6167\u6574\u7406\uff09<\/div>\n
2020\u5e74\u4e0a\u534a\u5e74\u5178\u578b\u5e76\u8d2d\u6848\u4f8b\uff1a<\/div>\n
1\uff09\u57fa\u56e0\u6d4b\u5e8f\u516c\u53f8Invitae\u548c\u5206\u5b50\u8bca\u65ad\u516c\u53f8ArcherDX\u5ba3\u5e03\u5408\u5e76\uff1b<\/div>\n
2\uff09FMI\u6536\u8d2d\u80bf\u7624\u7532\u57fa\u5316\u68c0\u6d4b\u516c\u53f8Lexent Bio\uff1b\u00a0<\/div>\n
3\uff09Illumina\u6536\u8d2d\u6570\u636e\u538b\u7f29\u516c\u53f8BlueBee\uff1b<\/div>\n
4\uff09\u7f57\u6c0f\u5ba3\u5e03\u5df2\u6536\u8d2d\u521d\u521b\u6d4b\u5e8f\u6280\u672f\u516c\u53f8Stratos Genomics\u516c\u53f8\uff1b\u00a0<\/div>\n
5\uff09\u836f\u4f01OncBioMune\u6536\u8d2d\u5206\u5b50\u8bca\u65ad\u516c\u53f8Avant Diagnostics\uff1b\u00a0<\/div>\n
6\uff09\u4e34\u5e8a\u8f85\u52a9\u51b3\u7b56\u5e73\u53f0DiscernDx\u6536\u8d2d\u8bca\u65ad\u516c\u53f8Luminist Labs\u3002<\/div>\n
\u5982\u4fde\u6ce2\u6240\u8a00\uff0c\u5728\u5de8\u5934\u9ad8\u4e3e\u9ad8\u6253\u7684\u7b56\u7565\u4e0b\uff0c\u4e13\u6ce8\u5728\u660e\u786e\u7684\u5dee\u5f02\u5316\u65b0\u573a\u666f\u4e0b\u3001\u5177\u5907\u65b0\u6280\u672f\u5148\u53d1\u4f18\u52bf\u7684\u521b\u65b0\u516c\u53f8\uff0c\u53ea\u6709\u5feb\u901f\u5b8c\u6210\u4ea7\u54c1\u7684\u573a\u666f\u5316\u9a8c\u8bc1\uff0c\u624d\u80fd\u591f\u6301\u7eed\u53d1\u5c55\uff08\u5305\u62ec\u72ec\u7acb\u53d1\u5c55\u6216\u6210\u4e3a\u5e76\u8d2d\u6807\u7684\uff09\u3002\u57fa\u56e0\u6167\u8ba4\u4e3a\uff0c\u5934\u90e8\u4f01\u4e1a\u7684\u62a4\u57ce\u6cb3\u7684\u5efa\u7acb\uff08\u6ca1\u6709\u66f4\u5927\u53ea\u6709\u6700\u5927\uff09\u53ca\u6a2a\u5411\u6269\u5c55\u5e02\u573a\uff08\u4ece\u57fa\u56e0\u5230\u751f\u547d\u5065\u5eb7\uff0c\u4ece\u68c0\u6d4b\u5230\u533b\u7597\uff09\uff0c\u5747\u8d8b\u540c\u4e8e\u5e76\u8d2d\u8def\u5f84\u3002<\/div>\n
\u00a0<\/div>\n
\u516d\u3001\u672a\u6ee1\u8db3\u7684\u9700\u6c42<\/div>\n
\u57fa\u4e8e\u5bf925\u4f4d\u653f\u7b56\u3001\u4e34\u5e8a\u3001\u79d1\u7814\u3001\u653f\u7b56\u53ca\u4ea7\u4e1a\u7aef\u7684\u521d\u6b65\u8c03\u7814\uff0c\u57fa\u56e0\u6167\u5f52\u7eb3\u603b\u7ed3\u884c\u4e1a\u672a\u6ee1\u8db3\u9700\u6c42\u5982\u4e0b\uff1a\u00a0<\/div>\n
1\uff09\u9057\u4f20\u54a8\u8be2\u662f\u5bf9\u9057\u4f20\u75be\u75c5\u8bca\u65ad\u800c\u8fdb\u884c\u9057\u4f20\u5b66\u68c0\u6d4b\u5fc5\u4e0d\u53ef\u5c11\u7684\u521a\u9700\u3002\u76ee\u524d\u4e1a\u5185\u51fa\u73b0\u76844\u4e2a\u201c\u66ff\u4ee3\u6a21\u5f0f\u201d\uff08\u5373\u7535\u8bdd\u9057\u4f20\u54a8\u8be2\u3001\u8fdc\u7a0b\u89c6\u9891\u9057\u4f20\u54a8\u8be2\u3001\u5c0f\u7ec4\u9057\u4f20\u54a8\u8be2\u548c\u5d4c\u5165\u5f0f\u9057\u4f20\u54a8\u8be2\uff09\uff0c\u5404\u6709\u4e0d\u53ef\u89e3\u51b3\u7684\u77ed\u5904\uff0c\u89c4\u8303\u6027\u7684\u4e0e\u54a8\u8be2\u8005\u4e00\u5bf9\u4e00\u7684\u9057\u4f20\u54a8\u8be2\u95e8\u8bca\u4ecd\u7136\u662f\u89e3\u51b3\u95ee\u9898\u7684\u6700\u597d\u6a21\u5f0f\u3002\u56e0\u6b64\uff0c\u5efa\u8bae\u56fd\u5bb6\u5c42\u9762\u52a0\u5feb\u6559\u80b2\u7cfb\u7edf\u5185\u7684\u4e34\u5e8a\u9057\u4f20\u54a8\u8be2\u4e13\u79d1\u6559\u80b2\u57f9\u517b\u53ca\u5176\u5b66\u4f4d\u5efa\u7acb\uff0c\u52a0\u5f3a\u533b\u7597\u536b\u751f\u7cfb\u7edf\u5bf9\u4e34\u5e8a\u9057\u4f20\u54a8\u8be2\u884c\u4e1a\u7684\u4e13\u4e1a\u89c4\u8303\u3002\u2014\u2014\u56fd\u9645\u77e5\u540d\u9057\u4f20\u75c5\u4e13\u5bb6 \u9646\u56fd\u8f89<\/div>\n
\u00a0<\/div>\n
2\uff09\u7f55\u89c1\u75c5\u65b9\u9762\uff1a\u2460\u57fa\u4e8e\u4e2d\u56fd\u4eba\u7fa4\u7684\u513f\u7ae5\u7f55\u89c1\u75c5\u5171\u4eab\u6570\u636e\u5e93\u5e94\u8be5\u5c3d\u5feb\u5efa\u7acb\uff0c\u5f62\u6210\u8868\u578b-\u57fa\u56e0\u578b\u4e00\u4f53\u5316\u7684\u670d\u52a1\u4e34\u5e8a\u8bca\u65ad\u7684\u516c\u5171\u5206\u6790\u5e73\u53f0\u3002\u2461\u5728\u56fd\u5185\u91cd\u8981\u7684\u513f\u7ae5\u8bca\u7597\u4e2d\u5fc3\uff0c\u5e94\u8be5\u7ec4\u7ec7\u4e00\u7cfb\u5217\u7684\u4e34\u5e8a\u591a\u4e2d\u5fc3\u7814\u7a76\uff0c\u89e3\u51b3\u6211\u56fd\u5e38\u89c1\u7684\u53ef\u9632\u53ef\u6cbb\u513f\u7ae5\u7f55\u89c1\u75c5\u7684\u9002\u5b9c\u8bca\u7597\u6280\u672f\u7684\u5efa\u7acb\u548c\u666e\u53ca\u3002\u2462\u57fa\u4e8e\u5e38\u89c1\u513f\u7ae5\u7f55\u89c1\u75c5\u5f00\u5c55\u65b0\u751f\u513f\u671f\u7b5b\u67e5\uff0c\u5c3d\u5feb\u5efa\u7acb\u4e34\u5e8a\u8bca\u65ad\u548c\u5e72\u9884\u7684\u89c4\u8303\u5316\u4e34\u5e8a\u51b3\u7b56\u4f53\u7cfb\uff0c\u5c24\u5176\u5728\u5371\u91cd\u65b0\u751f\u513f\u7684\u4e25\u91cd\u7f55\u89c1\u75c5\u7684\u7b5b\u67e5\u548c\u89c4\u8303\u8bca\u7597\u7b56\u7565\u65b9\u9762\u5e94\u8be5\u4f5c\u4e3a\u91cd\u8981\u653b\u514b\u7684\u96be\u70b9\u95ee\u9898\u3002\u00a0\u2014\u2014 \u590d\u65e6\u5927\u5b66\u513f\u79d1\u533b\u9662\u526f\u9662\u957f \u5468\u6587\u6d69<\/div>\n
\u00a0<\/div>\n
3\uff09\u4e34\u5e8a\u9057\u4f20\u75c5\u53ca\u751f\u7269\u5065\u5eb7\u5e94\u7528\u4e0a\u672a\u6ee1\u8db3\u7684\u9700\u6c42\u5305\u62ec\uff1a\u591a\u57fa\u56e0\u9057\u4f20\u3001\u8868\u89c2\u9057\u4f20\u3001\u7ebf\u7c92\u4f53\u9057\u4f20\u7b49\u7684\u9632\u63a7\u95ee\u9898\uff1b\u4ea7\u524d\u80ce\u513f\u8868\u578b\u7684\u6df1\u5165\u6316\u6398\u3001\u4ea7\u524d\u86cb\u767d\u6c34\u5e73\u7684\u68c0\u6d4b\u5728\u4ea7\u524d\u8bca\u65ad\u4e2d\u7684\u5e94\u7528\u95ee\u9898\u7b49\u3002\u00a0\u2014\u2014 \u4e0a\u6d77\u5e02\u7b2c\u4e00\u5987\u5a74\u4fdd\u5065\u9662\u80ce\u513f\u533b\u5b66\u90e8\u53ca\u4ea7\u524d\u8bca\u65ad\u4e2d\u5fc3\u8d1f\u8d23\u4eba \u5b59\u8def\u660e<\/div>\n
\u00a0<\/div>\n
4\uff092018\u5e749\u6708\uff0c\u56fd\u5bb6\u536b\u5065\u59d4\u51fa\u53f0\u300a\u5168\u56fd\u51fa\u751f\u7f3a\u9677\u7efc\u5408\u9632\u6cbb\u65b9\u6848\u300b\uff08\u56fd\u536b\u529e\u5987\u5e7c\u53d1\u30142018\u301519\u53f7 \uff09\u4e2d\u660e\u786e\u201c\u5e7f\u6cdb\u5f00\u5c55\u4ea7\u524d\u7b5b\u67e5\uff0c\u666e\u53ca\u5e94\u7528\u4ea7\u524d\u7b5b\u67e5\u9002\u5b9c\u6280\u672f\uff0c\u89c4\u8303\u5e94\u7528\u9ad8\u901a\u91cf\u57fa\u56e0\u6d4b\u5e8f\u7b49\u65b0\u6280\u672f\uff0c\u9010\u6b65\u5b9e\u73b0\u6000\u5b55\u5987\u5973\u5b5528\u5468\u524d\u5728\u81ea\u613f\u60c5\u51b5\u4e0b\u81f3\u5c11\u63a5\u53d71\u6b21\u4ea7\u524d\u7b5b\u67e5\u3002\u5bf9\u9ad8\u5371\u5b55\u5987\u8981\u6307\u5bfc\u5176\u53ca\u65f6\u5230\u6709\u8d44\u8d28\u7684\u533b\u7597\u673a\u6784\u63a5\u53d7\u4ea7\u524d\u8bca\u65ad\u670d\u52a1\u3002\u201d<\/div>\n
\u00a0\u00a0\u00a0\u00a0\u533b\u7597\u673a\u6784\u8fdb\u884c\u4ea7\u524d\u7b5b\u67e5\u4e0e\u8bca\u65ad\u6240\u4f7f\u7528\u7684\u8bbe\u5907\u4e0e\u8bd5\u5242\u5fc5\u987b\u5747\u53d6\u5f97\u56fd\u5bb6\u533b\u7597\u5668\u68b0\u751f\u4ea7\u8bb8\u53ef\u8bc1\uff0c\u7136\u800c\u8fc4\u4eca\u4e3a\u6b62\uff0c\u9664\u4e86\u5b55\u5987\u8840\u6d46\u6e38\u79bb\u80ce\u513fDNA\u65e0\u521b\u4ea7\u524d\u68c0\u6d4b21\u4e09\u4f53\u300118\u4e09\u4f53\u300113\u4e09\u4f53\u7684\u9ad8\u901a\u91cf\u6d4b\u5e8f\u8bd5\u5242\u53d6\u5f97\u56fd\u5bb6\u533b\u7597\u5668\u68b0\u8bc1\u4ee5\u5916\uff0c\u9ad8\u901a\u91cf\u6d4b\u5e8f\u6280\u672f\u5728\u5176\u4ed6\u9057\u4f20\u75c5\u7684\u7b5b\u67e5\u4e0e\u8bca\u65ad\u4e2d\u7684\u5e94\u7528\u5747\u4e0d\u5408\u6cd5\uff0c\u5927\u5927\u9650\u5236\u4e86\u9ad8\u901a\u91cf\u6d4b\u5e8f\u6280\u672f\u5728\u4ea7\u524d\u7b5b\u67e5\u4e0e\u8bca\u65ad\u4e2d\u7684\u5e94\u7528\uff0c\u65e2\u963b\u788d\u4e86\u9002\u5b9c\u6280\u672f\u7684\u666e\u53ca\u6027\uff0c\u4e5f\u589e\u52a0\u4e86\u533b\u7597\u673a\u6784\u7684\u4f7f\u7528\u6cd5\u5f8b\u98ce\u9669\u4e0e\u4e0d\u80fd\u5e94\u7528\u9020\u6210\u6f0f\u8bca\u7684\u533b\u7597\u98ce\u9669\u3002\u2014\u2014 \u5e7f\u4e1c\u7701\u5987\u5e7c\u4fdd\u5065\u9662\u533b\u5b66\u9057\u4f20\u4e2d\u5fc3\u4e3b\u4efb \u5c39\u7231\u534e<\/div>\n
\u00a0<\/div>\n
5\uff09\u57fa\u56e0\u68c0\u6d4b\u6807\u51c6\u4e0e\u6307\u5357\u7684\u8fdb\u4e00\u6b65\u5b8c\u5584\uff0c\u653f\u7b56\u652f\u6301\uff0c\u6570\u636e\u5b89\u5168\u3001\u4e92\u7528\u6027\u548c\u5206\u4eab\uff0c\u4ef7\u683c\u4e0e\u533b\u4fdd\uff0c\u533b\u52a1\u4eba\u5458\u5bf9\u57fa\u56e0\u68c0\u6d4b\u7ed3\u679c\u7684\u7406\u89e3\u548c\u7cbe\u51c6\u6cbb\u7597\u65b9\u6848\u7684\u9009\u62e9\u7b49\u3002\u672a\u6765\u9700\u8981\u63d0\u9ad8\u57fa\u56e0\u68c0\u6d4b\u7684\u51c6\u786e\u6027\u548c\u7a33\u5b9a\u6027\uff1b\u4eba\u5de5\u667a\u80fd\u548c\u6570\u5b57\u5316\u6280\u672f\u5728\u80bf\u7624\u7cbe\u51c6\u533b\u5b66\u4e2d\u7684\u5e94\u7528\u9010\u6e10\u589e\u52a0\u3002\u2014\u2014 \u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u9662\u7cbe\u51c6\u533b\u5b66\u4e2d\u5fc3\u526f\u4e3b\u4efb \u5f20\u6587\u5e9a<\/div>\n
\u00a0<\/div>\n
6\uff09\u5168\u5916\u663e\u5b50\u6d4b\u5e8f\u7528\u4e8e\u8d85\u58f0\u5f02\u5e38\u80ce\u513f\u5355\u57fa\u56e0\u4f20\u75c5\u98ce\u9669\u5224\u65ad\u65b9\u9762\u7684\u5e94\u7528\u4ef7\u503c\u5728\u4e34\u5e8a\u6570\u636e\u7684\u652f\u6491\u4e0b\u5df2\u5f97\u5230\u4e86\u8f83\u4e3a\u666e\u904d\u7684\u8ba4\u53ef\uff0c\u672a\u6765\u4e00\u5e74\u53ef\u80fd\u4f1a\u5f97\u5230\u66f4\u591a\u7684\u4e34\u5e8a\u4f7f\u7528\u3002\u6570\u636e\u5206\u6790\u7684\u6548\u7387\u548c\u53d1\u73b0\u81f4\u75c5\u53d8\u5f02\u7684\u80fd\u529b\u662f\u5f71\u54cd\u4e34\u5e8a\u5bf9\u8be5\u6280\u672f\u4fe1\u5fc3\u7684\u91cd\u8981\u56e0\u7d20\uff0c\u4e8c\u8005\u53d6\u51b3\u4e8e\u6570\u636e\u5171\u4eab\u548c\u5de5\u5177\u4f18\u5316\uff0c\u671f\u671b\u63a5\u4e0b\u6765\u76f8\u5173\u65b9\u5728\u8fd9\u65b9\u9762\u505a\u66f4\u591a\u7684\u52aa\u529b\u3002\u2014\u2014 \u7b2c\u4e09\u519b\u533b\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662(\u897f\u5357\u533b\u9662)\u4ea7\u524d\u8bca\u65ad\u4e2d\u5fc3\u4e3b\u4efb \u59da\u5b8f<\/div>\n
\u00a0<\/div>\n
7\uff09\u57fa\u4e8eNGS\u7684\u57fa\u56e0Panel\u68c0\u6d4b\u6b63\u5728\u6210\u4e3a\u8840\u6db2\u80bf\u7624\u8bca\u7597\u7684\u5e38\u89c4\u68c0\u67e5\u3002\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u3001\u6df1\u5ea6\u5168\u5916\u663e\u5b50\u7ec4\u6d4b\u5e8f\u3001\u4ee5\u53ca\u5355\u7ec6\u80de\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u9010\u6b65\u5e94\u7528\u3002\u4f46NGS\u5b9e\u9a8c\u6d41\u7a0b\u590d\u6742\u3001\u7ed3\u679c\u89e3\u8bfb\u5bf9\u4eba\u5458\u8981\u6c42\u9ad8\u3001\u68c0\u6d4b\u6210\u672c\u9ad8\u548c\u62a5\u544a\u5468\u671f\u957f\uff0c\u4ecd\u662f\u9650\u5236\u5176\u63a8\u5e7f\u5e94\u7528\u7684\u91cd\u8981\u56e0\u7d20\u3002\u60a3\u8005\u548c\u4e34\u5e8a\u8bca\u7597\u9700\u8981\u66f4\u81ea\u52a8\u5316\u3001\u4fbf\u4e8e\u63a8\u5e7f\u7684\u5b9e\u9a8c\u4f53\u7cfb\uff0c\u4ee5\u53ca\u4e34\u5e8a\u5e94\u7528\u76d1\u7ba1\u6a21\u5f0f\u7684\u521b\u65b0\u3002\u2014\u2014 \u5317\u4eac\u9646\u9053\u57f9\u533b\u9662\u8840\u6db2\u75c5\u7814\u7a76\u9662\u526f\u9662\u957f\u00a0\u5218\u7ea2\u661f<\/div>\n
\u00a0<\/div>\n
8\uff09\u5bf9\u4e8e\u5b8f\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6280\u672f\uff0c\u9700\u8981\u5206\u4e24\u6b65\u8d70\uff1a\u7b2c\u4e00\u6b65\uff0c\u75c5\u539f\u7b5b\u67e5\u9636\u6bb5\u3002\u4f46\u662f\u5bf9\u4e8e\u80fd\u5426\u51c6\u786e\u7b5b\u67e5\u5230\u81f4\u75c5\u75c5\u539f\uff0c\u8fd8\u9700\u8981\u505a\u4e24\u4e2a\u7ef4\u5ea6\u7684\u6280\u672f\u7a81\u7834\uff0c\u5305\u62ec\u2460 \u6e7f\u5b9e\u9a8c\u6280\u672f\u5c42\u9762\u7684\u7834\u58c1\u6280\u672f\u3001\u53bb\u5bbf\u4e3b\u6280\u672f\uff1b\u2461\u62a5\u544a\u73af\u8282\u7684\u75c5\u539f\u5b9a\u91cf\u5206\u6790\u6280\u672f\u3002\u76ee\u524d\u5e02\u573a\u4e0a\u5927\u591a\u6570mNGS\u4ea7\u54c1\u6280\u672f\u5f00\u53d1\u90fd\u805a\u7126\u4e8e\u6b64\u3002\u7b2c\u4e8c\u6b65\uff0c\u75c5\u539f\u7684\u6bd2\u529b\u548c\u836f\u654f\u9884\u6d4b\u3002\u75c5\u539f\u7684\u6bd2\u529b\u8ddf\u4e34\u5e8a\u9884\u540e\u7d27\u5bc6\u76f8\u5173\uff0c\u800c\u75c5\u539f\u5bf9\u5404\u79cd\u6297\u751f\u7d20\u7684\u654f\u611f\u7a0b\u5ea6\u662f\u6297\u751f\u7d20\u4f7f\u7528\u7684\u6700\u540e\u4e00\u6b65\u3002\u8be5\u90e8\u5206\u76ee\u524d\u5e02\u573a\u6210\u719f\u7684\u89e3\u51b3\u65b9\u6848\u5f88\u5c11\u3002\u2014\u2014 \u91d1\u5319\u57fa\u56e0CEO \u848b\u667a<\/div>\n
9\uff09\u6211\u4eec\u671f\u671b\u57283\u4e2a\u65b9\u9762\u89c1\u5230\u7a81\u7834\uff1a\u2460\u7a00\u6709\u80bf\u7624\u5355\u7ec6\u80de\u3001\u7279\u522b\u662fCTC\u7684\u9ad8\u7279\u5f02\u6027\u9274\u5b9a\u65b9\u6cd5\u6709\u4e34\u5e8a\u7a81\u7834\uff1b\u2461\u5747\u4e00\u6027\u66f4\u9ad8\u7684\u5355\u7ec6\u80deDNA WGA\u6269\u589e\u6280\u672f\u548c\u4ea7\u54c1\u3002\u2462\u80bf\u7624\u5355\u7ec6\u80de\u57fa\u56e0\u6d4b\u5e8f\u6280\u672f\u88ab\u66f4\u591a\u4e34\u5e8a\u533b\u751f\u6240\u63a5\u89e6\u3002\u2014\u2014 \u6d5a\u60e0\u751f\u7269\u521b\u59cb\u4eba \u960e\u707c\u8f89<\/div>\n
\u00a0<\/div>\n
10\uff09\u5229\u7528\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u6280\u672f\u8bfb\u957f\u66f4\u957f\u7684\u4f18\u52bf\uff0c\u5927\u91cf\u7269\u79cd\u57fa\u56e0\u7ec4\u88ab\u91cd\u65b0\u62fc\u63a5\uff0c\u4f7f\u5f97\u4eba\u4eec\u5bf9\u5168\u57fa\u56e0\u7ec4\u5e8f\u5217\u7684\u4e86\u89e3\u66f4\u5168\u9762\u3001\u66f4\u51c6\u786e\u3002\u4e0d\u5c11\u8fc7\u53bb\u5229\u7528\u4e8c\u4ee3\u6d4b\u5e8f\u6280\u672f\u5c1a\u65e0\u6cd5\u786e\u5b9a\u81f4\u75c5\u7a81\u53d8\u7684\u9057\u4f20\u75c5\u4f8b\uff0c\u901a\u8fc7\u957f\u8bfb\u957f\u7684\u65b0\u4e00\u4ee3\u6d4b\u5e8f\u6280\u672f\u660e\u786e\u4e86\u81f4\u75c5\u7a81\u53d8\u3002\u540c\u65f6\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u6280\u672f\u5728\u75c5\u539f\u4f53\u5feb\u68c0\u9886\u57df\u4e5f\u53d6\u5f97\u4e86\u7a81\u7834\uff0c\u4ece\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u6280\u672f\u5f00\u53d1\u7684\u884c\u4e1a\u751f\u6001\u6765\u770b\uff0c\u884c\u4e1a\u4e0a\u6e38\u7684\u6d4b\u5e8f\u4eea\u5668\u548c\u914d\u5957\u8bd5\u5242\u8fd8\u5904\u4e8e\u88ab\u5355\u4e00\u56fd\u5916\u4f01\u4e1a\u5784\u65ad\u7684\u5c40\u9762\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u884c\u4e1a\u4e0b\u6e38\u7684\u5e94\u7528\u4e0e\u670d\u52a1\u5e02\u573a\u5df2\u7ecf\u51fa\u73b0\u7206\u53d1\u5f0f\u589e\u957f\uff0c\u5e0c\u671b\u4ece\u56fd\u5bb6\u653f\u7b56\u5236\u5b9a\u5230\u8d44\u672c\u5e02\u573a\u8d44\u91d1\u6d41\u5411\u7b49\u5404\u65b9\u9762\uff0c\u90fd\u80fd\u591f\u66f4\u591a\u5730\u5411\u62e5\u6709\u5b8c\u5168\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u7684\u672c\u56fd\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u8bbe\u5907\u548c\u8bd5\u5242\u7684\u5f00\u53d1\u4f01\u4e1a\u3002\u2014\u2014 \u9f50\u78b3\u79d1\u6280\u521b\u59cb\u4eba \u8c22\u4e39<\/div>\n
\u00a0<\/div>\n
11\uff09\u7f55\u89c1\u75c5\u6d41\u884c\u75c5\u5b66\u4f53\u7cfb\u7684\u5efa\u7acb\u5c06\u6781\u5927\u5e26\u52a8\u6211\u56fd\u7f55\u89c1\u75c5\u7684\u7814\u7a76\u53ca\u5b64\u513f\u836f\u7684\u7814\u53d1\uff0c\u5e76\u8fdb\u4e00\u6b65\u4fc3\u8fdbWGS\/WES\u7b49\u6280\u672f\u7684\u4e34\u5e8a\u63a8\u5e7f\u5e94\u7528\u3002\u57fa\u4e8e\u4e34\u5e8a\u6570\u636e\u8868\u578b\u5316\u6280\u672f\u4e0e\u4eba\u5de5\u667a\u80fd\u6280\u672f\u5f62\u6210\u7684\u7f55\u89c1\u75c5\u7b5b\u67e5\u6280\u672f\uff0c\u4e5f\u5c06\u8fdb\u4e00\u6b65\u60e0\u53ca\u6211\u56fd\u60a3\u8005\uff0c\u63d0\u5347\u5404\u7ea7\u4e34\u5e8a\u673a\u6784\u7684\u7f55\u89c1\u75c5\u8bca\u7597\u6c34\u5e73\u3002\u2014\u2014 \u795e\u5dde\u6570\u7801\u533b\u7597\u9ad8\u7ea7\u526f\u603b\u88c1\u517c\u9996\u5e2d\u533b\u7597\u4fe1\u606f\u5b98 \u5f13\u5b5f\u6625<\/div>\n
\u00a0<\/div>\n
12\uff09\u968f\u7740\u4e91\u7684\u65f6\u4ee3\u6765\u4e34\uff0c\u57fa\u56e0\u5927\u6570\u636e\u968f\u7740\u5927\u6570\u636e\uff08Big data\uff09\u6f6e\u6d41\u4e5f\u8d8a\u6765\u8d8a\u5438\u5f15\u4e86\u5404\u4e2a\u9886\u57df\u7684\u4e13\u5bb6\u4e0e\u653f\u5e9c\u90e8\u95e8\u5173\u6ce8\u3002\u4f46\u57fa\u56e0\u5927\u6570\u636e\u4e0e\u5927\u6570\u636e\u6280\u672f\u7684\u6218\u7565\u610f\u4e49\uff0c\u5728\u4e8e\u4e0d\u4ec5\u4ec5\u662f\u638c\u63e1\u591a\u4e48\u5e9e\u5927\u7684\u4fe1\u606f\u6570\u636e\u91cf\uff0c\u800c\u66f4\u5728\u4e8e\u5982\u4f55\u5c06\u6781\u5bcc\u4e13\u4e1a\u610f\u4e49\u7684\u6570\u636e\u8fdb\u884c\u4e13\u4e1a\u5316\u7684\u5904\u7406\u3002\u6362\u8a00\u4e4b\uff0c\u57fa\u56e0\u5927\u6570\u636e\u4e0e\u533b\u7597\u4fe1\u606f\u5316\u5efa\u8bbe\u7ed3\u5408\uff0c\u5c3d\u7ba1\u8346\u68d8\u4e1b\u751f\u3001\u4efb\u91cd\u9053\u8fdc\uff0c\u8d8b\u52bf\u3001\u524d\u666f\u548c\u6210\u679c\u662f\u53ef\u4ee5\u9884\u89c1\u7684\uff0c\u4f46\u9700\u8981\u6709\u5fd7\u4e8e\u771f\u6b63\u7684\u201c\u533b\u5de5\u878d\u5408\u201d\uff0c\u6f5c\u5fc3\u7814\u7a76\u5b9e\u73b0\u7684\u8def\u5f84\u548c\u5173\u952e\u6280\u672f\uff0c\u63d0\u9ad8\u5bf9\u57fa\u56e0\u5927\u6570\u636e\u68c0\u6d4b\u6807\u51c6\u5316\u3001\u5e94\u7528\u7ed3\u5408\u94fe\u201c\u524d\u52a0\u5de5\u201d\u548c\u201c\u540e\u5b9e\u73b0\u201d\u3002\u2014\u2014 \u4e2d\u56fd\u975e\u516c\u7acb\u533b\u7597\u673a\u6784\u534f\u4f1a\u8bc4\u4ef7\u6807\u51c6\u4e13\u5bb6\u59d4\u5458\u4f1a\u4e3b\u59d4\u00a0\u9648\u654f\u751f<\/div>\n
\u00a0<\/div>\n
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\u00a0<\/div>\n
2\uff09\u8fdb\u51652020\u5e74\uff0c\u9057\u4f20\u8bca\u65ad\u6280\u672f\u5e26\u7ed9\u80ce\u513f\u9057\u4f20\u75c5\u7b5b\u67e5\u548c\u8bca\u65ad\u9886\u57df\u7684\u6700\u4e3b\u8981\u8fdb\u5c55\u662f\u80ce\u513f\u5168\u5916\u663e\u5b50\u7ec4\u6d4b\u5e8f\u548c\u6269\u5c55\u6027\u643a\u5e26\u8005\u7b5b\u67e5\u7684\u4e34\u5e8a\u5e94\u7528\u3002\u6269\u5c55\u6027\u643a\u5e26\u8005\u7b5b\u67e5\uff0c\u660e\u786e\u4e86\u592b\u5987\u5bf9\u4e8e\u5e38\u89c1\u9690\u6027\u9057\u4f20\u75c5\u7684\u81f4\u75c5\u6027\u7a81\u53d8\u643a\u5e26\u72b6\u6001\uff0c\u53ef\u4ee5\u5f88\u597d\u7684\u4e3a\u540e\u7eed\u7684\u4ea7\u524d\u8bca\u65ad\u6307\u660e\u65b9\u5411\u3002\u5982\u4f55\u5728\u73b0\u6709\u5f62\u52bf\u4e0b\uff0c\u66f4\u4fbf\u6377\u5730\u63d0\u4f9b\u4e13\u4e1a\u7684\u9057\u4f20\u54a8\u8be2\u670d\u52a1\uff1f\u6211\u8ba4\u4e3a\u662f\u57fa\u4e8e\u4e92\u8054\u7f51\u7684\u63d0\u4f9b\u8fdc\u7a0b\u9057\u4f20\u54a8\u8be2\uff0c\u4e5f\u8bb8\u8fd9\u662f\u5c06\u6765\u4ea7\u524d\u9057\u4f20\u75c5\u8bca\u65ad\u4e34\u5e8a\u6a21\u5f0f\u7684\u5de8\u5927\u8f6c\u53d8\u3002\u2014\u2014 \u5317\u4eac\u534f\u548c\u533b\u9662\u4ea7\u524d\u8bca\u65ad\u4e2d\u5fc3\u00a0\u848b\u5b87\u6797<\/div>\n
\u00a0<\/div>\n
3\uff09\u5c55\u671b\u75ab\u60c5\u4e4b\u4e0b\u7684\u672a\u6765\u4e00\u5e74\uff0c\u660e\u786e\u65b0\u51a0\u75c5\u6bd2\u7684\u4e2a\u4f53\u9057\u4f20\u6613\u611f\u6027\u3001\u5224\u65ad\u75c5\u6bd2\u57fa\u56e0\u7a81\u53d8\u7684\u8d8b\u52bf\u4e0e\u89c4\u5f8b\u3001\u5feb\u901f\u7814\u53d1\u9488\u5bf9\u7a81\u53d8\u75c5\u6bd2\u682a\u7684\u75ab\u82d7\u7b49\u663e\u5f97\u683c\u5916\u8feb\u5207\u3002\u2014\u2014 \u590d\u65e6\u5927\u5b66\u4ee3\u8c22\u5206\u5b50\u533b\u5b66\u6559\u80b2\u90e8\u91cd\u70b9\u5b9e\u9a8c\u5ba4 \u9a6c\u7aef<\/div>\n
\u00a0<\/div>\n
4\uff09mNGS \u5bf9\u672a\u77e5\u4f20\u67d3\u75c5\u7684\u75c5\u539f\u4f53\u68c0\u6d4b\u5177\u6709\u5f3a\u5927\u7684\u4f18\u52bf\u3002\u4f46\u5c1a\u4e0d\u80fd\u5b8c\u5168\u6307\u5bfc\u8010\u836f\u83cc\u6297\u611f\u67d3\u836f\u7269\u7684\u9009\u62e9\uff0c\u4e00\u662f\u76ee\u524d\u62a5\u9053\u7684\u8010\u836f\u57fa\u56e0\u578b\u4e0e\u8010\u836f\u8868\u578b\u7684\u5173\u8054\u7a0b\u5ea6\u8fd8\u5b58\u5728\u5dee\u8ddd\uff1b\u4e8c\u662f\u73b0\u6709\u68c0\u6d4b\u65b9\u6cd5\u56e0\u6210\u672c\u8003\u8651\u5bfc\u81f4\u8010\u836f\u76f8\u5173\u57fa\u56e0\u8986\u76d6\u5ea6\u8f83\u4f4e\uff0c\u96be\u4ee5\u9ad8\u7075\u654f\u5ea6\u5730\u68c0\u6d4b\u51fa\u76f8\u5173\u8010\u836f\u57fa\u56e0\u3002\u56e0\u6b64\u6025\u9700\u4e00\u4e2a\u5bf9\u4e8e\u5df2\u77e5\u6297\u751f\u7d20\u8010\u836f\u57fa\u56e0\u9884\u6d4b\u5177\u6709\u8f83\u4f4e\u7684\u5047\u9634\u6027\/\u5047\u9633\u6027\u7387\u3001\u53ef\u9884\u6d4b\u57fa\u56e0\u578b\u548c\u8868\u578b\u5173\u7cfb\u3001\u4e14\u4e0d\u65ad\u66f4\u65b0\u7684\u6570\u636e\u5e93\u3002\u9776\u5411\u6cbb\u7597\u4e0e\u514d\u75ab\u6cbb\u7597\u3001\u514d\u75ab\u6cbb\u7597\u8054\u5408\u5316\u7597\u5c06\u6210\u4e3a\u672a\u6765\u80bf\u7624\u6cbb\u7597\u7684\u65b0\u6a21\u5f0f\u3002\u5c06\u4f1a\u6709\u66f4\u591aHRD\uff08\u540c\u6e90DNA\u4fee\u590d\u7f3a\u9677\uff09\u4ee5\u53caHRR\u68c0\u6d4b\u4ea7\u54c1\u8d70\u5411\u4e34\u5e8a\u3002\u2014\u2014 \u5409\u6797\u5927\u5b66\u7b2c\u4e00\u533b\u9662\u57fa\u56e0\u8bca\u65ad\u4e2d\u5fc3\u4e3b\u4efb \u59dc\u8273\u82b3<\/div>\n
\u00a0<\/div>\n
5\uff09\u4eceSARS\u3001\u57c3\u535a\u62c9\u75c5\u6bd2\u3001\u6bd2\u9ec4\u74dc\u5927\u80a0\u6746\u83cc\u3001\u79bd\u6d41\u611f\u75c5\u6bd2\u5230\u4eca\u5929\u7684\u65b0\u51a0\u75c5\u6bd2\uff0c\u6211\u4eec\u53ef\u4ee5\u6e05\u6670\u7684\u770b\u5230\uff0c\u66f4\u5feb\u66f4\u65b9\u4fbf\u66f4\u51c6\u786e\u66f4\u666e\u53ca\u7684\u5b8f\u57fa\u56e0\u7ec4\u6280\u672f\u53d1\u5c55\u7684\u8feb\u5207\u6027\u3002\u2014\u2014\u00a0\u6d59\u6c5f\u5927\u5b66\u533b\u5b66\u9662 \/ \u8fea\u5b89\u8bca\u65ad \u7941\u9e23<\/div>\n
\u00a0<\/div>\n
6\uff09\u80bf\u7624\u6db2\u4f53\u6d3b\u68c0\u6709\u7740\u5de8\u5927\u7684\u5e94\u7528\u524d\u666f\uff0c\u5305\u62ec\u80bf\u7624\u7684\u590d\u53d1\u8f6c\u79fb\u98ce\u9669\u76d1\u6d4b\u3001\u80bf\u7624\u6cbb\u7597\u7597\u6548\u7684\u5feb\u901f\u8bc4\u4ef7\u3001\u9ad8\u5371\u4eba\u7fa4\u7684\u65e9\u671f\u7b5b\u67e5\u548c\u8f85\u52a9\u8bca\u65ad\u3001\u4e2a\u4f53\u5316\u6cbb\u7597\u65b9\u6848\u7684\u9009\u62e9\u3001\u65b0\u7684\u80bf\u7624\u836f\u7269\u7684\u7b5b\u9009\u548c\u80bf\u7624\u8f6c\u79fb\u673a\u5236\u7684\u7814\u7a76\u7b49\u3002\u76ee\u524d\u7814\u7a76\u7684\u70ed\u70b9\u3001\u96be\u70b9\u5df2\u7136\u8f6c\u5411\u65e9\u671f\u7b5b\u67e5\u3001\u6cdb\u764c\u79cd\u7c7b\u578b\u3001\u7532\u57fa\u5316\u6d4b\u5e8f\u7b49\u9886\u57df\u3002\u2014\u2014 \u5e7f\u897f\u533b\u79d1\u5927\u5b66\u57fa\u56e0\u7ec4\u4e0e\u4e2a\u4f53\u5316\u533b\u5b66\u7814\u7a76\u4e2d\u5fc3\u4e3b\u4efb \u83ab\u66fe\u5357<\/div>\n
\u00a0<\/div>\n
7\uff09\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u662f\u8fd1\u5e74\u6765\u57fa\u56e0\u6d4b\u5e8f\u9886\u57df\u7684\u7a81\u7834\u6027\u6280\u672f\u4e4b\u4e00\uff0c\u901a\u8fc7\u5bf9\u65b0\u9c9c\u51b7\u51bb\u7ec4\u7ec7\u5207\u7247\u5904\u7406\uff0c\u7f6e\u4e8e\u5305\u542b\u5f15\u7269\u548c\u4f4d\u7f6e\u4fe1\u606f\u7684\u82af\u7247\u4e0a\uff0c\u56fa\u5b9a\u7ec4\u7ec7\u5e76\u900f\u5316\u91ca\u653e\u7ec6\u80de\u5185RNA\uff0c\u4ece\u800c\u6355\u83b7\u7279\u5b9a\u7a7a\u95f4\u4f4d\u7f6e\u4e0a\u7684\u57fa\u56e0\u8868\u8fbe\u4fe1\u606f\u3002\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u6280\u672f\u7684\u51fa\u73b0\u5c06\u6709\u52a9\u4e8e\u79d1\u5b66\u5bb6\u7814\u7a76\u80bf\u7624\u7b49\u590d\u6742\u75be\u75c5\u7684\u5fae\u73af\u5883\u548c\u7a7a\u95f4\u7ec4\u7ec7\u7ed3\u6784\u3002\u4f8b\u5982\uff0c\u4eca\u5e74\u4e03\u6708\u4efdChen\u7b49\u4eba\u5728Cell\u4e0a\u53d1\u8868\u7684\u8bba\u6587\u4e2d\uff0c\u5229\u7528\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u7814\u7a76\u6dc0\u7c89\u6837\u6591\u5757\u5468\u56f4\u76f4\u5f84100\u5fae\u7c73\u533a\u57df\u7684\u8868\u8fbe\u53d8\u5316\uff0c\u4e3a\u963f\u5c14\u5179\u6d77\u9ed8\u75c7\u548c\u5176\u4ed6\u8111\u90e8\u75be\u75c5\u7684\u7814\u7a76\u63d0\u4f9b\u4e86\u65b0\u7684\u89c6\u89d2\u3002\u6b64\u5916\uff0c\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u4e5f\u53ef\u4ee5\u548c\u5355\u7ec6\u80de\u6d4b\u5e8f\u8054\u5408\u5206\u6790\uff0c\u4ece\u800c\u5b9e\u73b0\u5bf9\u4e0d\u540c\u7ec6\u80de\u4e9a\u7fa4\u7684\u7a7a\u95f4\u5b9a\u4f4d\uff0c\u4ee5\u53ca\u5bf9\u4e0d\u540c\u7a7a\u95f4\u4f4d\u7f6e\u8fdb\u884c\u7ec6\u80de\u7c7b\u578b\u6ce8\u91ca\u3002\u2014\u2014 \u5357\u4eac\u822a\u7a7a\u822a\u5929\u5927\u5b66\u00a0\u59dc\u4f1f<\/div>\n
\u00a0<\/div>\n
8\uff09\u00a0\u5728\u4ea7\u4e1a\u7ed3\u6784\u65b9\u9762\uff0c\u76ee\u524d\u4e0b\u6e38\u5728\u62d3\u5bbd\u5e94\u7528\uff0c\u4e0a\u6e38\u5728\u5411\u5236\u9020\u53ca\u539f\u8f85\u6599\u5ef6\u4f38\uff1b\u5bf9\u4e8e\u4f20\u7edf\u5e94\u7528\u573a\u666f\u6765\u8bf4\uff0c\u6210\u672c\u63a7\u5236\u6210\u4e3a\u5173\u952e\uff1b\u5bf9\u4e8e\u65b0\u5e94\u7528\u573a\u666f\u6765\u8bf4\uff0c\u4e0e\u5176\u4ed6\u68c0\u6d4b\u6280\u672f\u7684\u7ade\u4e89\u6bd4\u8f83\u6210\u4e3a\u5173\u952e\u3002\u6211\u56fd\u57fa\u56e0\u884c\u4e1a\u4e0b\u4e00\u4e2a\u7206\u53d1\u70b9\uff0c\u6211\u60f3\u662f\u5728\u57fa\u56e0\u6cbb\u7597\u9886\u57df\uff1b\u5c24\u5176\u662f\u5bf9\u4e8e\u9057\u4f20\u6027\u75be\u75c5\u989d\u57fa\u56e0\u6cbb\u7597\u3002\u2014\u2014 \u9ad8\u7279\u4f73\u6267\u884c\u5408\u4f19\u4eba \u738b\u6d77\u86df<\/div>\n
\u00a0<\/div>\n
9\uff09\u4ea7\u4e1a\u7ed3\u6784\u4e9f\u9700\u5411\u4e13\u4e1a\u5316\u3001\u96c6\u7ea6\u5316\u65b9\u5411\u7a81\u7834\uff0c\u9700\u8981\u66f4\u660e\u786e\u5b9a\u4f4d\u7684\u4ea7\u54c1\u578b\u3001\u670d\u52a1\u578b\u516c\u53f8\u5206\u5de5\u5408\u4f5c\u63d0\u5347\u6574\u4e2a\u4ea7\u4e1a\u80fd\u7ea7\u3002\u4ece\u8fd9\u4e2a\u89d2\u5ea6\u4e0a\u770b\uff0c\u4e00\u65b9\u9762\u6709\u6cd5\u89c4\u9010\u6b65\u660e\u6670\u3001\u8d44\u672c\u5411\u5934\u90e8\u96c6\u4e2d\u3001\u884c\u4e1a\u7ade\u4e89\u52a0\u5267\u7b49\u6709\u5229\u56e0\u7d20\uff1b\u4f46\u4e5f\u6709\u5e02\u573a\u6f5c\u529b\u91ca\u653e\u3001\u5c42\u7ea7\u4e0b\u6c89\u3001\u6cd5\u89c4\u76f8\u5bf9\u6ede\u540e\u7b49\u4e0d\u5229\u56e0\u7d20\uff08\u5e02\u573a\u6f5c\u529b\u91ca\u653e\u5bf9\u884c\u4e1a\u662f\u5229\u597d\uff0c\u4f46\u4e5f\u5197\u4f59\u4e86\u6076\u6027\u7ade\u4e89\u7684\u7a7a\u95f4\uff0c\u5ef6\u7f13\u4e86\u4e13\u4e1a\u5316\u3001\u96c6\u7ea6\u5316\u8fdb\u7a0b\uff09\u3002\u672a\u6765\u534a\u5e74\u8fd9\u7c7b\u7a81\u7834\u5728\u65b0\u51a0\u7b49\u653f\u7b56\u5f3a\u52bf\u4ecb\u5165\u7684\u9886\u57df\u53ef\u80fd\u66f4\u5feb\u51fa\u73b0\uff0c\u4f46\u5728\u80bf\u7624\u7b49\u590d\u6742\u4e1a\u52a1\u9886\u57df\u8fd8\u5f88\u96be\u5b9e\u73b0\u3002\u9884\u8ba1\u4f9d\u9760\u5e02\u573a\u81ea\u4e3b\u8c03\u8282\u7684\u884c\u4e1a\u6574\u5408\u8fd8\u9700\u8981\u6301\u7eed\u4e00\u6bb5\u65f6\u95f4\uff0c\u8fd9\u671f\u95f4\u9700\u8981\u66f4\u591a\u7684\u517c\u5177\u5f00\u653e\u5305\u5bb9\u548c\u8d23\u4efb\u5f3a\u5316\u7684\uff08\u5982\u5f3a\u8d23\u4efb\u627f\u62c5\u7684LDT\uff09\u914d\u5957\u6cd5\u89c4\uff1b\u66f4\u4e13\u4e1a\u7406\u6027\u7684\u6295\u8d44\u9074\u9009\u548c\u63a8\u52a8\uff1b\u5f53\u7136\u4e5f\u9700\u8981\u4f01\u4e1a\u4e3b\u4f53\u66f4\u805a\u7126\u4e13\u4e1a\u5316\u5b9a\u4f4d\u52a0\u5feb\u7814\u53d1\u548c\u5e02\u573a\u5f00\u53d1\u8fdb\u7a0b\u3002\u53ea\u6709\u8fd9\u51e0\u65b9\u9762\u5408\u529b\u5e76\u884c\uff0c\u6574\u4e2a\u4ea7\u4e1a\u53d1\u5c55\u624d\u80fd\u5c3d\u5feb\u8fdb\u5165\u826f\u6027\u7ade\u4e89\u53d1\u5c55\u7684\u53d1\u5c55\u9636\u6bb5\u3002\u2014\u2014 \u4e91\u950b\u57fa\u91d1\u8463\u4e8b\u603b\u7ecf\u7406\u00a0\u674e\u6587\u7f61\u00a0<\/div>\n
\u00a0<\/div>\n
10\uff09\u5927\u57fa\u56e0\u884c\u4e1a\u76ee\u524d\u5df2\u7ecf\u9010\u6b65\u7531\u201cdiscovery\u201d-\u201cmapping\u201d-\u201cidentification\u201d\u53d1\u5c55\u5230\u201cmanipulation\u201d\u8fd9\u4e00\u65b0\u7684\u57fa\u56e0\u4fe1\u606f\u5e94\u7528\u9636\u6bb5\u3002\u524d\u4e24\u4e2a\u9636\u6bb5\u5df2\u7ecf\u5904\u4e8e\u6210\u719f\u7684\u884c\u4e1a\u53d1\u5c55\u5468\u671f\u4e2d\uff0c\u5e76\u4e14\u51ed\u501f\u4e0d\u65ad\u8fed\u4ee3\u4f18\u5316\u7684\u6280\u672f\u5de5\u5177\uff08\u4e8c\u4ee3\u6d4b\u5e8f\uff0c\u5355\u7ec6\u80de\u6d4b\u5e8f\u7b49\uff09\u5f80\u66f4\u7ec6\u7684\u57fa\u56e0\u4fe1\u606f\u9897\u7c92\u5ea6\u53d1\u5c55\u3002\u800c\u540e\u4e24\u4e2a\u9636\u6bb5\u5206\u522b\u5904\u4e8e\u4e34\u5e8a\u5e02\u573a\u5feb\u901f\u53d1\u5c55\u671f\uff08\u4ee5\u80bf\u7624\uff0c\u611f\u67d3\u6027\u75be\u75c5\u7684\u7cbe\u51c6\u8bca\u65ad\u4e0e\u4f34\u968f\u8bca\u65ad\u4e3a\u4ee3\u8868\uff09\u4e0e\u884c\u4e1a\u5bfc\u5165\u671f\uff08\u4ee5\u57fa\u56e0\u6cbb\u7597\uff0c\u57fa\u56e0\u5408\u6210\u4e3a\u4ee3\u8868\uff09\u3002<\/div>\n
\u53e6\u4e00\u65b9\u9762\uff0c\u5927\u57fa\u56e0\u4ea7\u4e1a\u94fe\u4e0a\u4e0b\u6e38\u6709\u660e\u663e\u7684\u4e00\u4f53\u5316\u8d8b\u52bf\uff0c\u7531\u5206\u6563\u72ec\u7acb\u7684\u5de5\u5177\u6027\u4ea7\u54c1\uff08\u57fa\u56e0\u6d4b\u5e8f\uff0c\u8bca\u65ad\u8bd5\u5242\u76d2\uff0c\u4f34\u968f\u8bca\u65ad\uff0c\u7597\u6548\u8bc4\u4f30\uff09\u5f80\u6db5\u76d6\u4ea7\u4e1a\u94fe\u5404\u73af\u8282\u7684\u7efc\u5408\u6027\u8bca\u7597\u89e3\u51b3\u65b9\u6848\u53d1\u5c55\u3002\u4e0a\u6e38\u4f01\u4e1a\u9010\u6b65\u5ef6\u4f38\u51fa\u4e0b\u6e38\u4e1a\u52a1\uff0c\u4e0b\u6e38\u4f01\u4e1a\u5219\u5728\u4e0a\u6e38\u4fe1\u606f\u57fa\u7840\u4e0a\u63d0\u4f9b\u4e00\u4f53\u5316\u89e3\u51b3\u65b9\u6848\u3002\u672a\u6765\u7684\u884c\u4e1a\u589e\u957f\u5f15\u64ce\u5c06\u4f1a\u51fa\u73b0\u5728\u4e2a\u4f53\u5316\u514d\u75ab\u7597\u6cd5\uff0c\u7ec6\u80de\u7597\u6cd5\u4e0e\u57fa\u56e0\u6cbb\u7597\u7b49\u9886\u57df\u3002\u2014\u2014 \u7d2b\u725b\u57fa\u91d1\u6295\u8d44\u603b\u76d1 \u4fde\u6ce2<\/div>\n
\u00a0<\/div>\n
11\uff09\u57fa\u4e8eCAPP-seq\u6280\u672f\u7684LUNG-CLiP\u518d\u6b21\u9a8c\u8bc1\u4e86\u7a81\u53d8\u68c0\u6d4b\u5728\u80bf\u7624\u65e9\u68c0\u5e94\u7528\u7684\u6781\u9650\uff0cThrive\u7684DETECT-A\u7814\u7a76\u5448\u73b0\u4e86\u5728\u524d\u77bb\u6027\u961f\u5217\u4e2d\u65e9\u68c0\u6280\u672f\u7684\u8868\u73b0\uff0c\u5728\u6280\u672f\u9a8c\u8bc1\u4e4b\u5916\u53c8\u5411\u4e34\u5e8a\u6548\u80fd\u8bc4\u4f30\u8d70\u4e86\u4e00\u5927\u6b65\u3002\u800c\u57fa\u4e8e\u6db2\u4f53\u6d3b\u68c0\u7684\u5206\u5b50\u6b8b\u7559\u75c5\u7076\uff08MRD\uff09\u8bc4\u4f30\u6280\u672f\u5f00\u59cb\u4ee5\u5e72\u9884\u6027\u7684\u8bbe\u8ba1\u65b9\u5f0f\u5d4c\u5165\u8f85\u52a9\u6cbb\u7597\u7684\u4e34\u5e8a\u7814\u7a76\u3002\u2014\u2014 \u71c3\u77f3\u533b\u5b66COO \u63e3\u5c11\u5764<\/div>\n
\u00a0<\/div>\n
12\uff09\u7ecf\u8fc7\u524d\u51e0\u5e74\u7684\u79d1\u7814\u79ef\u7d2f\uff0c\u6709\u4e9b\u65e9\u8bca\u65e9\u7b5b\u516c\u53f8\u5f00\u59cb\u53d1\u8868\u4e00\u4e9b\u56de\u987e\u6027\u7684\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\uff1b\u5728\u63a5\u4e0b\u6765\u76841-2 \u5e74\u91cc\uff0c\u4f1a\u6709\u66f4\u591a\u7684\u524d\u77bb\u6027\u4e34\u5e8a\u7814\u7a76\uff0c\u751a\u81f3\u5305\u62ec\u5e72\u9884\u6027\u7814\u7a76\u3002\u4e0b\u4e00\u4e2a\u6218\u573a\u5c31\u662fIVD \u4ea7\u54c1\u5f00\u53d1\uff0c\u8fd9\u5c31\u8981\u6c42\u5f00\u53d1\u8005\u5168\u76d8\u8003\u8651\u4ea7\u54c1\u7684\u4e34\u5e8a\u9700\u6c42\u548c\u793e\u4f1a\u4ef7\u503c\u3001\u5f00\u53d1\u96be\u5ea6\u3001\u4ea7\u54c1\u4ef7\u683c\uff0c\u4ee5\u53ca\u5728\u5927\u89c4\u6a21\u5e94\u7528\u573a\u666f\u4e0b\u7684\u53ef\u64cd\u4f5c\u6027\uff1b\u6709\u5b9e\u529b\u7684\u4e2d\u56fd\u516c\u53f8\u548c\u4ea7\u54c1\u8fdb\u5165\u56fd\u9645\u5e02\u573a\uff08\u5305\u62ec\u8d44\u672c\u5e02\u573a\uff09\uff0c\u4e0e\u56fd\u9645\u7ade\u4e89\u5bf9\u624b\u4e00\u8f83\u9ad8\u4f4e\u3002\u56e0\u4e3a\u65e9\u8bca\u65e9\u7b5b\u662f\u4e2a\u8017\u65f6\u8017\u94b1\u7684\u5927\u5de5\u7a0b\uff0c\u6211\u9884\u671f\u4e1a\u754c\u4f1a\u6709\u66f4\u591a\u7684\u8d44\u6e90\u6574\u5408\u3001\u5171\u540c\u5f00\u53d1\uff0c\u6bd4\u5982\u8bf4\uff0c\u5927\u578b\u4e34\u5e8a\u961f\u5217\u6837\u672c\u7684\u5171\u4eab\uff0c\u5f71\u50cf\u6280\u672f\u548c\u5206\u5b50\u68c0\u6d4b\u7684\u4e92\u8865\uff0c\u533b\u9662\u3001\u4f53\u68c0\u3001\u4fdd\u9669\u4e1a\u52a1\u5728\u5168\u6c11\u5065\u5eb7\u67b6\u6784\u4e0b\u7684\u4e92\u52a8\u3002\u2014\u2014 \u57fa\u51c6\u533b\u7597\u521b\u59cb\u4eba \u8303\u5efa\u5175<\/div>\n
\u00a0<\/div>\n
13\uff09\u4f34\u968f\u7528\u836f\u9886\u57df\uff0cTMB\u4f5c\u4e3a\u514d\u75ab\u6cbb\u7597\u4f34\u968f\u6307\u6807\u5f97\u5230FDA\u8ba4\u53ef\u5e94\u8be5\u662f\u4e2a\u91cc\u7a0b\u7891\u6027\u7684\u4e8b\u4ef6\uff0c\u53e6\u5916HRD\u4f34\u968fParp\u6291\u5236\u5242\u7684\u8fdb\u5c55\u4e5f\u5f97\u5230\u5e7f\u6cdb\u8ba4\u53ef\uff0c\u5927Panel\u7684\u4e34\u5e8a\u5e94\u7528\u53d6\u5f97\u91cd\u5927\u7a81\u7834\uff1b\u5728\u80bf\u7624\u65e9\u7b5b\u9886\u57df\uff0c\u901a\u8fc7\u68c0\u6d4bcfDNA\u4e0a\u5305\u62ec\u7a81\u53d8\u548c\u7532\u57fa\u5316\u4fe1\u53f7\u4e3a\u57fa\u7840\u7684\u80bf\u7624\u65e9\u671f\u68c0\u6d4b\u6280\u672f\u4e0a\u534a\u5e74\u8bb8\u591a\u91cd\u5927\u8fdb\u5c55\uff0c\u9884\u793a\u7740\u8be5\u9886\u57df\u8fdb\u5165\u5feb\u901f\u53d1\u5c55\u9636\u6bb5\u3002\u5c55\u671b\u672a\u6765\uff0c\u6709\u4e09\u4e2a\u660e\u663e\u8d8b\u52bf\uff1a\u2460\u6d4b\u5e8f\u5e73\u53f0\u4e0a\uff0c\u968f\u7740\u56fd\u4ea7\u6d4b\u5e8f\u4eea\u7684\u6210\u719f\u5e76\u83b7\u5f97\u4e34\u5e8a\u8ba4\u53ef\uff0c\u56fd\u4ea7\u5316\u66ff\u4ee3\u7684\u8fdb\u7a0b\u4f1a\u52a0\u901f\uff1b\u2461\u65b0\u7684\u6280\u672f\u4e0a\uff0c\u5355\u7ec6\u80de\u6280\u672f\u7684\u8fc5\u731b\u53d1\u5c55\uff0c\u4f1a\u5728\u80bf\u7624\u7684\u4e34\u5e8a\u79d1\u7814\u548c\u836f\u7269\u7814\u53d1\u4e0a\u5e7f\u6cdb\u5e94\u7528\uff1b\u2462\u6db2\u4f53\u6d3b\u68c0\u7684\u80bf\u7624\u65e9\u7b5b\u6280\u672f\u4f1a\u8fdb\u4e00\u6b65\u6210\u719f\uff0c\u5e76\u9010\u6b65\u627e\u5230\u4e34\u5e8a\u843d\u5730\u7684\u5177\u4f53\u5e94\u7528\u573a\u666f\u3002\u2014\u2014 \u5409\u56e0\u52a0CEO \u6613\u946b<\/div>\n
\u00a0<\/div>\n
14) 20\u5728\u751f\u80b2\u5065\u5eb7\u9886\u57df\u7684\u91cd\u5927\u6280\u672f\u548c\u5e94\u7528\u8fdb\u5c55\uff0c\u7531\u5317\u4eac\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u4e54\u6770\u9662\u58eb\u7275\u5934\uff0c\u5168\u56fd8\u5bb6\u751f\u6b96\u4e2d\u5fc3\u5171\u540c\u53c2\u4e0e\u7684\u65e0\u521b\u80da\u80ce\u690d\u5165\u6f5c\u80fd\u7b5b\u67e5\u7684\u591a\u4e2d\u5fc3\u4e34\u5e8a\u8bd5\u9a8c\u6b63\u5f0f\u542f\u52a8\u3002\u5728\u56fd\u5185\u5916\u5c55\u5f00\u591a\u9879\u5355\u4e2d\u5fc3\u7684\u4e34\u5e8a\u7814\u7a76\uff0cNICS\u6709\u6f5c\u529b\u4f5c\u4e3a\u4e00\u79cd\u964d\u4f4e\u6d41\u4ea7\u7387\uff0c\u63d0\u9ad8\u598a\u5a20\u7387\u7684\u65e0\u521b\u4f24\u80da\u80ce\u79fb\u690d\u6f5c\u80fd\u8bc4\u4f30\u6280\u672f\u3002\u2014\u2014 \u4ebf\u5eb7\u57fa\u56e0CEO \u9646\u601d\u5609<\/div>\n
\u00a0<\/div>\n
15\uff09\u672a\u6765\u4e00\u5e74\uff0c\u4e5f\u662f\u5e02\u573a\u4ea7\u54c1\u5dee\u5f02\u5316\u7ade\u4e89\u6700\u91cd\u8981\u7684\u4e00\u5e74\u3002\u5bf9\u4e8e\u672a\u6765\u4e00\u5e74\u7684\u7ade\u4e89\u8d8b\u52bf\u5c06\u4e3b\u8981\u805a\u7126\u5728\u4ee5\u4e0b\u51e0\u4e2a\u65b9\u9762\uff1a\u2460\u81f4\u75c5\u75c5\u539f\u7684\u7cbe\u51c6\u7b5b\u67e5\u548c\u9884\u6d4b\uff0c\u5305\u62ec\u533a\u5206\u5177\u4f53\u5e94\u7528\u573a\u666f\uff0c\u505a\u5230\u66f4\u52a0\u7cbe\u7ec6\u5316\u7ec6\u5206\uff0c\u6bd4\u5982\u547c\u5438\u9053\u611f\u67d3\u75c5\u539f\u7b5b\u67e5\u4ea7\u54c1\u548c\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u611f\u67d3\u75c5\u539f\u7b5b\u67e5\u4ea7\u54c1\u7b49\uff1b\u2461\u75c5\u539f\u83cc\u7684\u836f\u654f\u9884\u6d4b\uff1b\u2462\u5c06\u5bbf\u4e3b\u7684\u4fe1\u606f\u7eb3\u5165\u75be\u75c5\u9884\u6d4b\u6a21\u578b\uff0c\u4e3a\u4e34\u5e8a\u63d0\u4f9b\u66f4\u591a\u6709\u4ef7\u503c\u7684\u53c2\u8003\u4fe1\u606f\u3002\u4f8b\u5982\u5bf9\u4e8e\u79fb\u690d\u60a3\u8005\u7684cfDNA\u53ef\u7528\u6765\u540c\u65f6\u76d1\u6d4b\u75c5\u539f\u611f\u67d3\u548c\u79fb\u690d\u6392\u5f02\u60c5\u51b5\u3002\u2014\u2014 \u91d1\u5319\u57fa\u56e0CEO \u848b\u667a<\/div>\n
\u00a0<\/div>\n
16\uff092020\u5e74\u4e0a\u534a\u5e74\uff0c\u57fa\u56e0\u68c0\u6d4b\u9886\u57df\u6bd4\u8f83\u5f15\u4eba\u77a9\u76ee\u7684\u6280\u672f\u4e0e\u5e94\u7528\u8fdb\u5c55\u5f53\u5c5eBDA (blocker displacement amplification)\u548cmNGS (metagenomics NGS)\u3002BDA\u662f\u9488\u5bf9\u6837\u672c\u4e2d\u4f4e\u4e30\u5ea6\u7684\u57fa\u56e0\u53d8\u5f02\u8fdb\u884c\u9009\u62e9\u6027\u653e\u5927\u7684\u521b\u65b0\u6280\u672f\uff0c\u53ef\u68c0\u6d4b\u4f4e\u81f3\u5343\u5206\u4e4b\u4e00\u542b\u91cf\u7684\u57fa\u56e0\u53d8\u5f02\u5e76\u4e0d\u9700\u8981\u589e\u52a0\u6d4b\u5e8f\u6570\u636e\u91cf\uff0c\u5b9e\u73b0\u4e86\u4e1a\u754c\u957f\u671f\u6e34\u671b\u7684\u4f4e\u6210\u672c\u6e38\u79bb\u80bf\u7624DNA (ctDNA)\u68c0\u6d4b\uff0c\u53ef\u7528\u4e8e\u6253\u9020\u4e34\u5e8a\u771f\u6b63\u9700\u8981\u7684\u80bf\u7624\u6db2\u4f53\u6d3b\u68c0\u4ea7\u54c1\u3002\u2014\u2014\u00a0\u9605\u5c14\u57fa\u56e0\u5b9e\u9a8c\u5ba4\u670d\u52a1\u90e8VP \u9648\u4e91\u5f1f<\/div>\n
\u00a0<\/div>\n
17\uff09\u2460\u57fa\u56e0\u4ea7\u4e1a\u5316\u53d1\u5c55\uff0c\u4ece\u4e00\u76f4\u4ee5\u6765\u7684\u57fa\u56e0\u533b\u5b66\u5065\u5eb7\u4e3a\u4e3b\u4f53\uff0c\u5f00\u59cb\u5411\u57fa\u56e0\u533b\u5b66\u5065\u5eb7\u4e0e\u57fa\u56e0\u751f\u7269\u5b89\u5168\uff0c\u4e24\u8005\u5e76\u91cd\u65b9\u5411\u8f6c\u578b\u3002\u2461\u57fa\u56e0\u79d1\u6280\u5f00\u53d1\u4e2d\u975e\u5e38\u91cd\u8981\u7684\u751f\u7269\u4fe1\u606f\u5206\u6790\uff0c\u5728\u4ea7\u4e1a\u5316\u5927\u6570\u636e\u652f\u6491\u4e0b\uff0c\u5c06\u4e0eAI\u6df1\u5ea6\u878d\u5408\u751a\u81f3\u88ab\u98a0\u8986\u6027\u6539\u9020\uff0c\u4ece\u800c\u6781\u5927\u63d0\u5347\u524d\u8005\u7684\u7cbe\u51c6\u6027\u3001\u65f6\u6548\u6027\u3001\u524d\u77bb\u6027\u548c\u53ef\u56de\u6eaf\u6027\u3002\u2462\u4e00\u6279\u5934\u90e8\u578b\u3001\u594b\u8fdb\u578b\u57fa\u56e0\u516c\u53f8\uff0c\u5c06\u6210\u4e3a\u56fd\u5bb6\u75c5\u539f\u9632\u63a7\u4f53\u7cfb\u65b0\u4e00\u8f6e\u521b\u65b0\u5efa\u8bbe\u4e2d\u7684\u751f\u529b\u519b\u3001\u91cd\u8981\u53c2\u4e0e\u8005\u3001\u91cd\u8981\u8d21\u732e\u8005\uff0c\u65b0\u7684\u76f8\u5173\u884c\u4e1a\u6807\u51c6\u4e0e\u89c4\u8303\u5c06\u5e94\u65f6\u800c\u751f\u3002\u2014\u2014 \u4f18\u8fc5\u533b\u5b66\u8463\u4e8b\u957f \u738b\u5efa\u4f1f<\/div>\n
\u00a0<\/div>\n
18) \u5355\u7ec6\u80de\u6d4b\u5e8f\u4e0e\u514d\u75ab\u7ec4\u5e93\u76f8\u7ed3\u5408\uff0c\u5177\u6709\u91cd\u5927\u7684\u4e34\u5e8a\u8f6c\u5316\u6f5c\u529b\uff0c\u4e3a\u4e2a\u6027\u5316\u6cbb\u7597\u63d0\u4f9b\u4f9d\u636e\u3002\u5728\u4ea7\u4e1a\u65b9\u9762\uff0c\u56fd\u4ea7\u5316\u66ff\u4ee3\u5316\u7684\u8fdb\u5ea6\u4f1a\u52a0\u5feb\u3002\u2014\u2014 \u8054\u5ddd\u751f\u7269\u8463\u4e8b\u957f\u00a0\u90ce\u79cb\u857e<\/div>\n
19\uff09WGS\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6b63\u5728\u6210\u4e3aGermline Mutation\u7684\u4e3b\u6d41\uff0c\u5c24\u5176\u662f\u533b\u5b66\u9057\u4f20\u548c\u7fa4\u4f53\u7814\u7a76\u9886\u57df\u3002\u4ece\u8ba1\u7b97\u6280\u672f\u7684\u89d2\u5ea6\u770b\uff0c\u4eca\u5e74\u4e0b\u534a\u5e74\uff0c\u7279\u522b\u662f9-10\u6708\u4f1a\u8fce\u6765\u6570\u636e\u6d2a\u5cf0\uff0c\u4e91\u8ba1\u7b97\u662f\u5206\u6d41\u524a\u5cf0\u6700\u597d\u7684\u65b9\u6848\u3002\u57fa\u56e0\u7ec4\u5206\u6790\u8ba1\u7b97\u51fa\u73b0\u4e86\u591a\u79cd\u67b6\u6784\u548c\u7279\u6027\u7684\u8ba1\u7b97\u65b9\u6848\uff0c\u9664Intel\u4e4b\u5916\uff0c\u5305\u62ecAMD\u3001ARM\u3001NVIDIA GPU\u3001FPGA\u7b49\u3002\u2014\u2014 GeneDock\uff08\u805a\u9053\u79d1\u6280\uff09\u521b\u59cb\u4eba\u00a0\u674e\u53a6\u620e<\/div>\n
20\uff09\u672a\u6765\u4e00\u4e24\u5e74\u6b27\u7f8e\u56fd\u9645\u5934\u90e8\u4f01\u4e1a\u5c06\u5904\u4e8e\u201c\u6df1\u6316\u6d1e\u7f13\u79f0\u738b\u201d\u7684\u9636\u6bb5\uff0c\u79ef\u7d2f\u6570\u636e\u3002\u56fd\u9645\u836f\u4f01\u5c06\u6df1\u5ea6\u4ecb\u5165\u57fa\u56e0\u9886\u57df\u9ad8\u79d1\u6280\u7684\u53d1\u5c55\uff0c\u9996\u5148\u5b9e\u73b0\u6db2\u6001\u6d3b\u68c0\u521b\u65b0\u6280\u672f\u5728\u786e\u8bca\u764c\u75c7\u60a3\u8005\u8eab\u4e0a\u7684\u4e34\u5e8a\u5e94\u7528\uff0c\u4e3a\u5c06\u6765\u5728\u5065\u5eb7\u4eba\u7fa4\u5b9e\u73b0\u764c\u75c7\u65e9\u7b5b\u6253\u4e0b\u57fa\u7840\u3002\u00a0\u2014\u2014 \u6167\u6e21\u533b\u7597\u521b\u59cb\u4eba \u8d3e\u58eb\u4e1c<\/div>\n
21\uff09\u672a\u6765\u4e00\u6bb5\u65f6\u95f4\uff08\u9884\u8ba1\u4e00\u5e74\u4ee5\u4e0a\uff09\u80a0\u9053\u8425\u517b\u76f8\u5173\u4ea7\u4e1a\u4f1a\u8fdb\u5165\u7cbe\u7ec6\u5316\u8425\u517b\u7ba1\u7406\u7684\u65f6\u4ee3\uff0c\u901a\u8fc7\u7ed3\u5408\u751f\u6d3b\u4e60\u60ef\uff0c\u4e2a\u4eba\u57fa\u56e0\u7ec4\u60c5\u51b5\uff0c\u80a0\u9053\u6216\u75be\u75c5\u90e8\u4f4d\u5fae\u751f\u6001\u7b49\u591a\u7ec4\u5b66\u4fe1\u606f\uff0c\u83b7\u5f97\u4e2a\u4f53\u7279\u5f81\u4fe1\u606f\uff0c\u518d\u4f9d\u6258\u4e13\u4e1a\u7684\u4e34\u5e8a\u8425\u517b\u5e08\u7ed9\u51fa\u4e2a\u6027\u5316\u7684\u8425\u517b\u610f\u89c1\u3002\u76f8\u5e94\u5730\uff0c\u4e0b\u6e38\u7684\u4f01\u4e1a\u4e5f\u4f1a\u6574\u5408\u4e2a\u4f53\u591a\u7ec4\u5b66\u4fe1\u606f\uff0c\u4ece\u800c\u7814\u53d1\u5bf9\u5e94\u7684\u996e\u98df\u4ea7\u54c1\u3001\u5e72\u9884\u4ea7\u54c1\u3001\u751a\u81f3\u662f\u836f\u54c1\u3002\u2014\u2014 \u5fae\u5065\u5eb7\u57fa\u56e0\u521b\u59cb\u4eba \u6234\u6587\u9b41<\/div>\n
\u00a0<\/div>\n
22\uff09\u672a\u6765\u68c0\u6d4b\u65b9\u6cd5\u5c06\u9010\u6e10\u4ece\u5b9e\u9a8c\u5ba4\u4eba\u5de5\u64cd\u4f5c\u5b9e\u65f6\u8367\u5149\u5b9a\u91cfPCR\u5b9e\u9a8c\u8f6c\u53d8\u4e3aPOCT\u3002\u56fd\u5185IVD\u884c\u4e1a\u5c06\u8d8a\u6765\u8d8a\u6ce8\u91cdPOCT\u4ea7\u54c1\u7684\u5e02\u573a\u53d1\u5c55\uff0c\u672a\u6765\u53d1\u5c55\u8d8b\u52bf\u5c06\u7740\u91cd\u4e8e\u6027\u80fd\u6bd4\u62fc\uff0c\u5373\u64cd\u4f5c\u3001\u7cbe\u5ea6\u3001\u8fd0\u884c\u3001\u901a\u91cf\u3001\u5b89\u5168\u6027\u7b49\u3002\u2014\u2014\u00a0\u91d1\u51c6\u57fa\u56e0\u7814\u53d1\u603b\u76d1 \u9648\u6653\u5b81<\/div>\n
\u00a0<\/div>\n
23\uff09\u968f\u7740\u57fa\u4e8e\u5b8f\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u7684\u5fae\u751f\u7269\u7ec4\u53c2\u8003\u57fa\u56e0\u96c6\u7684\u79ef\u7d2f\uff0c\u4ee5\u53ca\u7eb3\u7c73\u5b54\u7b49\u4e09\u4ee3\u6d4b\u5e8f\u6280\u672f\u7684\u6210\u719f\u548c\u5b8c\u5584\uff0c\u4ee5\u53ca\u5b8f\u8f6c\u5f55\u7ec4\u3001\u5b8f\u86cb\u767d\u8d28\u7ec4\u3001\u4ee3\u8c22\u7ec4\u548c\u57f9\u517b\u7ec4\u5b66\u7b49\u6280\u672f\u7684\u8fdb\u4e00\u6b65\u53d1\u5c55\u548c\u5e94\u7528\uff0c\u7ed3\u5408\u52a8\u7269\u6a21\u578b\u4ee5\u53ca\u4eba\u7fa4\u5927\u6570\u636e\u548c\u4e34\u5e8a\u5206\u6790\u7684\u7814\u7a76\u79ef\u7d2f\uff0c\u4f1a\u6301\u7eed\u7684\u4e3a\u4ea7\u4e1a\u8f6c\u5316\u7814\u53d1\u63d0\u4f9b\u65b0\u7684\u63a8\u52a8\u529b\u3002\u2014\u2014 \u70ed\u5fc3\u80a0\u7814\u7a76\u9662\u9996\u5e2d\u79d1\u5b66\u5bb6 \u674e\u4e39\u5b9c\u00a0<\/div>\n
\u00a0<\/div>\n
24\uff09\u5728\u521b\u65b0\u836f\u884c\u4e1a\uff0c\u5305\u62ecCGT\u9886\u57df\uff0c\u76ee\u524d\u7ba1\u7ebf\u91cd\u590d\uff0c\u9776\u70b9\u624e\u5806\u3002\u00a0\u4e00\u662f\u5efa\u8bae\u66f4\u591a\u5173\u6ce8\u4e00\u4e9b\u4e2d\u56fd\u7279\u8272\u7684\u764c\u79cd\u548c\u5176\u4ed6\u75be\u75c5\uff1b\u4e8c\u662f\u66f4\u91cd\u89c6\u4e0e\u533b\u751f\u7684\u5408\u4f5c\uff0c\u5f00\u53d1\u66f4\u591a\u4e34\u5e8a\u4e9f\u9700\u7684\u836f\u7269\u3002\u2014\u2014\u00a0\u5409\u51ef\u57fa\u56e0 \u5ffb\u5bc5\u5f3a<\/div>\n
\u00a0<\/div>\n
2. \u98ce\u9669\u5206\u6790<\/div>\n
\u5e38\u542c\u89c1\u5371\u4e2d\u85cf\u673a\uff0c\u5bf9\u5e94\u7684\uff0c\u6211\u4eec\u4e0d\u80fd\u5ffd\u89c6\uff0c\u5c45\u5b89\u601d\u5371\uff0c\u5305\u62ec\u56e0\u75ab\u60c5\u5e26\u6765\u6682\u65f6\u5229\u597d\u5e02\u573a\u5c06\u6301\u7eed\uff0c\u4f46\u4e0d\u4f1a\u6301\u7eed\u592a\u4e45\u3002\u57fa\u56e0\u6167\u8ba4\u4e3a\u76ee\u524d\u57fa\u56e0\u884c\u4e1a\u98ce\u9669\u5b58\u5728\u5982\u4e0b\u51e0\u70b9\uff1a<\/div>\n
1\uff09\u7814\u53d1\u98ce\u9669\uff1a\u57fa\u56e0\u884c\u4e1a\u7814\u53d1\u9879\u76ee\u6280\u672f\u6c34\u5e73\u9ad8\u3001\u53d1\u5c55\u53d8\u5316\u5feb\u3001\u8d44\u8d28\u62a5\u8bc1\u5468\u671f\u8f83\u957f\uff0c\u7814\u53d1\u6295\u5165\u6210\u672c\u8fc7\u9ad8\uff0c\u5728\u7814\u53d1\u8fc7\u7a0b\u4e2d\uff0c\u7814\u53d1\u56e2\u961f\u3001\u7ba1\u7406\u6c34\u5e73\u3001\u6280\u672f\u8def\u7ebf\u9009\u62e9\u90fd\u4f1a\u5f71\u54cd\u4ea7\u54c1\u7814\u53d1\u7684\u6210\u8d25\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
2\uff09\u56fd\u9645\u73af\u5883\u98ce\u9669\u53ca\u76d1\u7ba1\u4e0d\u786e\u5b9a\u6027\uff0c\u7279\u522b\u6d77\u5916\u6269\u5f20\u7684\u5934\u90e8\uff0c\u4ee5\u53ca\u548c\u6d77\u5916\u4f01\u4e1a\u5408\u4f5c\u7684\u6a21\u5f0f\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
3\uff09\u57fa\u56e0\u6cbb\u7597\u7b49\u6280\u672f\u98ce\u9669\u30027\u6708 6 \u65e5\uff0c\u4e00\u540d\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08MM\uff09\u60a3\u8005\u63a5\u53d7\u6cd5\u56fd\u751f\u7269\u5236\u836f\u516c\u53f8Cellectis \u516c\u53f8UCARTCS1A \u7ec6\u80de\u7597\u6cd5\uff08\u4e00\u79cd\u9488\u5bf9\u9776\u70b9 CS1 \u8fdb\u884c\u5f00\u53d1\u7684\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u7684\u901a\u7528\u578b CAR-T \u7597\u6cd5\uff09\u4e34\u5e8a\u8bd5\u9a8c\u540e\u6b7b\u4ea1\uff0cFDA \u7d27\u6025\u6682\u505c\u8be5\u8bd5\u9a8c\uff1b\u00a0<\/div>\n
\u00a0<\/div>\n
4\uff09\u8de8\u754c\u5408\u4f5c\u7684\u8d44\u91d1\u53ca\u6570\u636e\u5229\u597d\uff0c\u5e26\u6765\u4ea7\u54c1\u8bbe\u8ba1\u53ca\u6570\u636e\u5b89\u5168\u7684\u4e0d\u786e\u5b9a\u6027\u30024\u6708\uff0c\u767e\u5ea6\u4e0e\u4e2d\u56fdCDC\u75c5\u6bd2\u75c5\u9884\u9632\u63a7\u5236\u6240\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\u534f\u8bae\uff0c\u53cc\u65b9\u5c06\u8054\u5408\u8bbe\u7acb\u201c\u4e2d\u56fdCDC\u5e94\u6025\u6280\u672f\u4e2d\u5fc3-\u767e\u5ea6\u57fa\u56e0\u6d4b\u5e8f\u5de5\u4f5c\u7ad9\u201d\uff0c5\u6708\uff0c\u674e\u5f66\u5b8f\u548c\u4ee5\u901a\u8baf\u4f5c\u8005\u53c2\u4e0e\u53d1\u5e03\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u53d1\u5e03\u7684\u6700\u5927\u98df\u7ba1\u9cde\u72b6\u7ec6\u80de\u764c\u57fa\u56e0\u7ec4\u56fe\u8c31\u3002\u683c\u529b\u5730\u4ea7\u5b50\u516c\u53f817.26\u4ebf\u5143\u5165\u80a1\u79d1\u534e\u751f\u7269\u3002<\/div>\n
\u4ee5\u4e0a\u5185\u5bb9\uff0c\u7531\u4e8e\u4fe1\u606f\u66f4\u65b0\u8fed\u4ee3\u8f83\u5feb\u53ca\u884c\u4e1a\u7279\u6b8a\u6027\uff0c\u96be\u514d\u6709\u758f\u6f0f\uff0c\u6b22\u8fce\u8ba8\u8bba\u3002\u66f4\u591a\u4ea7\u4e1a\u5206\u6790\u53ca\u8fdb\u5c55\u8ffd\u8e2a\u8bf7\u89c1\u57fa\u56e0\u6167\u5c06\u53d1\u5e03\u7684\u300a\u57fa\u56e0\u5927\u6570\u636e\u667a\u80fd\u751f\u4ea7\u53ca\u5206\u6790\u300b<\/a>\u884c\u7814\u62a5\u544a<\/a>\u3001\u300a\u4e2d\u56fd\u4e34\u5e8aNGS\u5e94\u7528\u9700\u6c42\u8c03\u7814\u300b\u84dd\u76ae\u4e66\u3001\u300a2021\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b\uff0c\u6b22\u8fce\u5173\u6ce8\u53ca\u51a0\u540d\u652f\u6301\u5408\u4f5c\u3002<\/div>\n
\u6b22\u8fce\u7559\u8a00\u8ba8\u8bba\u3002\u6211\u4eec\u5c06\u4ece\u7cbe\u5f69\u7559\u8a00\u4e2d\u62bd\u53d6\u5e78\u8fd0\u8bfb\u8005\u8d60\u4e88\u7eb8\u8d28\u7248\u300a2020\u57fa\u56e0\u884c\u4e1a\u62a5\u544a\u300b\u3002<\/div>\n
\u00a0<\/div>\n
\u53c2\u8003\u8d44\u6599\uff1a<\/div>\n
1.\u00a0https:\/\/strategyforexecs.com\/industry-life-cycle<\/div>\n
2.\u00a0http:\/\/www.xinhuanet.com\/politics\/leaders\/2020-07\/30\/c_1126306023.htm<\/div>\n
3.https:\/\/translations.state.gov\/2020\/07\/20\/commerce-department-adds-eleven-chinese-entities-implicated-in-human-rights-abuses-in-xinjiang-to-the-entity-list<\/div>\n
4. \u4e01\u9999\u56ed\uff1a\u75ab\u60c5\u5b9e\u65f6\u5730\u56fe<\/div>\n
5.\u00a0\u56fd\u52a1\u9662\u529e\u516c\u5385\u5370\u53d1\u300a\u6df1\u5316\u533b\u836f\u536b\u751f\u4f53\u5236\u6539\u97692020\u5e74\u4e0b\u534a\u5e74\u91cd\u70b9\u5de5\u4f5c\u4efb\u52a1\u300b\u00a0<\/div>\n
6. \u79d1\u6280\u90e8\u516c\u5e03\u300a\u5173\u4e8e\u63a8\u8fdb\u56fd\u5bb6\u6280\u672f\u521b\u65b0\u4e2d\u5fc3\u5efa\u8bbe\u7684\u603b\u4f53\u65b9\u6848\uff08\u6682\u884c\uff09\u300b\u00a0<\/div>\n
7. \u300a\u57fa\u56e0\u7ec4\u5b66\u300b\uff0c\u6768\u7115\u660e\u7f16\u8457<\/div>\n
8.\u00a0Xingdong Chen et. al,Non-invasive early detection of cancer four years before conventional diagnosis using a blood test,Nature Communications, 2020<\/div>\n
9.https:\/\/www.genomeweb.com\/sequencing\/stanford-team-debuts-epic-seq-method-detect-classify-cancer-cfdna-fragment-patterns<\/div>\n
10.\u00a0https:\/\/www.fda.gov<\/div>\n
\u00a0<\/div>\n
\u63a8\u8350\u9605\u8bfb<\/div>\n
\u57fa\u56e0\u4ea7\u4e1a\u7684\u9ece\u660e\u524d\u9759\u6084\u6084<\/a><\/div>\n
\u57fa\u56e0\u3001\u5927\u6570\u636e\u548c\u65b0\u57fa\u5efa<\/a><\/div>\n
\u5bf9\u8bdd\u67f4\u6620\u723d\u3001\u9648\u4e91\u5f1f<\/a><\/div>\n
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