{"id":9055,"date":"2020-08-17T00:03:34","date_gmt":"2020-08-16T16:03:34","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100015504&idx=1&sn=6107cb1ef1dfd27397da79e794c5ee0d&chksm=6b714f275c06c6317d5ed3b72e49593af28bcb3cb34ae406afd78db4b7ecfe86d90e3a3407ac#rd"},"modified":"2026-04-02T09:27:04","modified_gmt":"2026-04-02T01:27:04","slug":"995197","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2020\/08\/17\/995197\/","title":{"rendered":"\u5468\u62a5\u4e28\u534e\u897f2\u4ebf\u5143\u91c7\u8d2d\u5341\u4e07\u4f8b\u7f55\u89c1\u75c5WGS\uff0c\u4f34\u968f\u8bca\u65ad\u8bd5\u5242\u4e34\u5e8a\u8bd5\u9a8c\u539f\u5219\u53d1\u5e03\uff0c\u8d5b\u9ed8\u98de\u653e\u5f03\u6536\u8d2d\u51ef\u6770"},"content":{"rendered":"
\n
\"RmFicvQBAkgAQYPF5QmOPSP5gG9OuVpL987Hp0GmCugH6p7WjV0kJRyIJmk6VCBQsntaSNhPAib1GQztQlFQVA8Q\"\/<\/figure><\/div>\n\n
\u4e73\u817a\u764c\u4e2d\u53d1\u73b0\u201c\u56db\u94feDNA\u7ed3\u6784\u201d<\/div>\n
\u6765\u6e90\/Nature<\/div>\n
\u5934\u6761<\/div>\n
\u25a0\u00a0\u534e\u897f\u533b\u96622\u4ebf\u5143\u91c7\u8d2d\u5341\u4e07\u4f8b\u7f55\u89c1\u75c5WGS<\/div>\n
\u8fd1\u65e5\uff0c\u636e\u91c7\u62db\u7f51\u516c\u5e03\u4fe1\u606f\uff0c\u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u96622020\u5e749\u6708\u653f\u5e9c\u610f\u5411\u663e\u793a\uff0c\u8ba1\u5212\u91c7\u8d2d\u5341\u4e07\u4f8b\u4e2d\u56fd\u7f55\u89c1\u75c5\u60a3\u8005\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f(WGS)\u3002\u9488\u5bf9\u6b64\u6d88\u606f\uff0c\u76f8\u5173\u4e34\u5e8a\u4e13\u5bb6\u79f0\uff1a\u4e24\u4e2a\u4ebf\u7684\u6807\u7684\uff0c\u5fc5\u5c06\u5e26\u6765\u4e2d\u56fd\u7f55\u89c1\u75c5\u4e34\u5e8a\u9057\u4f20\u5b66\u7814\u7a76\u548c\u7cbe\u51c6\u8bca\u6cbb\u65b0\u6280\u672f\u5f00\u53d1\u7684\u7cfb\u7edf\u5316\u89c4\u6a21\u5316\u98a0\u8986\u5f0f\u53d1\u5c55\uff0c\u672a\u6765\u53ef\u671f\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.bidcenter.com.cn\/news-103218304-2.html<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u4f34\u968f\u8bca\u65ad\u8bd5\u5242\u4e34\u5e8a\u8bd5\u9a8c\u539f\u5219\u53d1\u5e03<\/div>\n
\u65e5\u524d\uff0c\u6839\u636e\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c402020\u5e74\u5ea6\u533b\u7597\u5668\u68b0\u6ce8\u518c\u6280\u672f\u6307\u5bfc\u539f\u5219\u5236\u4fee\u8ba2\u8ba1\u5212\u7684\u6709\u5173\u8981\u6c42\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u533b\u7597\u5668\u68b0\u6280\u672f\u5ba1\u8bc4\u4e2d\u5fc3\u7ec4\u7ec7\u8d77\u8349\u53d1\u5e03\u4e86\u300a\u5df2\u4e0a\u5e02\u6297\u80bf\u7624\u836f\u7269\u7684\u4f34\u968f\u8bca\u65ad\u8bd5\u5242\u4e34\u5e8a\u8bd5\u9a8c\u6307\u5bfc\u539f\u5219\u300b\u5f81\u6c42\u610f\u89c1\u7a3f\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cmde.org.cn\/CL0004\/21446.html<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u8d5b\u9ed8\u98de\u653e\u5f03\u6536\u8d2d\u51ef\u6770<\/div>\n
8\u670813\u65e5\uff0c\u8d5b\u9ed8\u98de(Thermo fisher)\u5ba3\u5e03\u7ec8\u6b62\u6536\u8d2d\u51ef\u6770\uff08QIAGEN\uff09\uff0c\u6839\u636e\u53cc\u65b9\u7b7e\u8ba2\u7684\u534f\u8bae\uff0c\u51ef\u6770\u5c06\u5411\u8d5b\u9ed8\u98de\u652f\u4ed89500\u4e07\u7f8e\u5143\u8d39\u7528\u3002\u6536\u8d2d\u7ec8\u6b62\u6d88\u606f\u53d1\u5e03\u540e\uff0c\u51ef\u6770\u80a1\u4ef7\u4e0b\u8dcc\u4e861%\u3002<\/div>\n
\u00a0<\/div>\n
\u91cd\u5927\u653f\u7b56<\/div>\n
\u25a0\u00a0FDA\u52a0\u901f\u6279\u51c6DMD\u521b\u65b0\u7597\u6cd5<\/div>\n
\u8fd1\u65e5\uff0cFDA\u5ba3\u5e03\u52a0\u901f\u6279\u51c6\u65e5\u672c\u65b0\u836f\u682a\u5f0f\u4f1a\u793e\uff08Nippon Shinyaku\uff09\u5b50\u516c\u53f8NS Pharma\u5f00\u53d1\u7684Viltepso\uff08viltolarsen\uff09\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u7279\u5b9a\u675c\u6c0f\u808c\u8425\u517b\u4e0d\u826f\uff08DMD\uff09\u60a3\u8005\u3002\u8fd9\u4e9b\u60a3\u8005\u786e\u8ba4\u643a\u5e26\u53ef\u4ee5\u7528\u5916\u663e\u5b5053\u8df3\u8dc3\u6cbb\u7597\u7684DMD\u57fa\u56e0\u7a81\u53d8\uff0c\u8fd9\u662fFDA\u6279\u51c6\u7684\u7b2c\u4e8c\u79cd\u9488\u5bf9\u643a\u5e26\u8be5\u7c7b\u7a81\u53d8\u60a3\u8005\u7684\u9776\u5411\u6cbb\u7597\u836f\u7269\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.fda.gov\/news-events\/<\/div>\n
\u300a\u4e2d\u56fd\u4e34\u5e8aNGS\u5e94\u7528\u9700\u6c42\u8c03\u7814\u300b<\/a>\u84dd\u76ae\u4e66\u00a0\u00a0\u00a0<\/div>\n
\u8bda\u9080\u51a0\u540d\u5408\u4f5c<\/div>\n\n
\n
\"RmFicvQBAkgC8Yjlv26vBria6vd2a2iaWYvNfLw1IZiayE5ytXicyZibEy2eiaolUO7FcO4ibvWDMicyY8LuFyx0CeS40UQ\"\/<\/figure><\/div>\n\n
\u00a0<\/div>\n
\u25a0\u00a0\u56fd\u5185\u9996\u6279\u773c\u5e95AI\u8f85\u52a9\u8bca\u65ad\u8f6f\u4ef6III\u7c7b\u8bc1<\/div>\n
\u8fd1\u65e5\uff0cNMPA\u6279\u51c6\u4e86\u9996\u62792\u6b3e\u7cd6\u5c3f\u75c5\u89c6\u7f51\u819c\u75c5\u53d8AI\u8bca\u65ad\u8f6f\u4ef6\u4ea7\u54c1\u83b7\u5f97III\u7c7b\u533b\u7597\u5668\u68b0\u6ce8\u518c\u8bc1\uff0c\u5206\u522b\u6765\u81ea\u6df1\u5733\u7845\u57fa\u667a\u80fd\u79d1\u6280\u6709\u9650\u516c\u53f8\u751f\u4ea7\u4ee5\u53ca\u4e0a\u6d77\u9e70\u77b3\u533b\u7597\u79d1\u6280\u6709\u9650\u516c\u53f8\u3002\u4e0a\u8ff0\u4ea7\u54c1\u5747\u91c7\u7528\u57fa\u4e8e\u5377\u79ef\u795e\u7ecf\u7f51\u7edc\u7684\u81ea\u52a9\u8bbe\u8ba1\u7684\u7f51\u7edc\u7ed3\u6784\uff0c\u57fa\u4e8e\u5206\u7c7b\u6807\u6ce8\u7684\u773c\u5e95\u56fe\u50cf\u6570\u636e\uff0c\u5bf9\u7b97\u6cd5\u6a21\u578b\u8fdb\u884c\u8bad\u7ec3\u548c\u9a8c\u8bc1\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a02020\u5e74\u5ea6\u56fd\u5bb6\u6770\u9752\u540d\u5355\u51fa\u7089<\/div>\n
8\u670811\u65e5\uff0c\u56fd\u5bb6\u81ea\u7136\u79d1\u5b66\u57fa\u91d1\u59d4\u5458\u4f1a\u53d1\u5e03\u4e86\u300a2020\u5e74\u5ea6\u56fd\u5bb6\u6770\u51fa\u9752\u5e74\u79d1\u5b66\u57fa\u91d1\u5efa\u8bae\u8d44\u52a9\u9879\u76ee\u7533\u8bf7\u4eba\u540d\u5355\u300b\u3002<\/div>\n
\u540d\u5355\u4fe1\u606f>><\/div>\n
http:\/\/www.nsfc.gov.cn\/publish\/portal0\/tab442\/info78439.htm<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u56fd\u52a1\u9662\u53d1\u5e03\u6761\u4f8b<\/div>\n
\u4fdd\u969c\u4e2d\u5c0f\u4f01\u4e1a\u652f\u4ed830\u5929\u56de\u6b3e<\/div>\n
\u8fd1\u65e5\uff0c\u56fd\u52a1\u9662\u516c\u5e03\u300a\u4fdd\u969c\u4e2d\u5c0f\u4f01\u4e1a\u6b3e\u9879\u652f\u4ed8\u6761\u4f8b\u300b\uff0c\u81ea2020\u5e749\u67081\u65e5\u8d77\u65bd\u884c\u3002\u89c4\u5b9a\u201c\u673a\u5173\u3001\u4e8b\u4e1a\u5355\u4f4d\u4ece\u4e2d\u5c0f\u4f01\u4e1a\u91c7\u8d2d\u8d27\u7269\u3001\u5de5\u7a0b\u3001\u670d\u52a1\uff0c\u5e94\u5f53\u81ea\u8d27\u7269\u3001\u5de5\u7a0b\u3001\u670d\u52a1\u4ea4\u4ed8\u4e4b\u65e5\u8d7730\u65e5\u5185\u652f\u4ed8\u6b3e\u9879\uff1b\u5408\u540c\u53e6\u6709\u7ea6\u5b9a\u7684\uff0c\u4ed8\u6b3e\u671f\u9650\u6700\u957f\u4e0d\u5f97\u8d85\u8fc760\u65e5\u201d\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.gov.cn\/zhengce\/<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u676d\u5dde\u94b1\u5858\u65b0\u533a\u6295\u8d44\u8d85840\u4ebf\u5143<\/div>\n
\u5efa\u8bbe\u751f\u7269\u533b\u836f\u4ea7\u4e1a\u5e73\u53f0<\/div>\n
8\u670812\u65e5\uff0c\u676d\u5dde\u94b1\u5858\u65b0\u533a\u4e3e\u884c\u751f\u7269\u533b\u836f\u4e07\u4ea9\u5343\u4ebf\u65b0\u4ea7\u4e1a\u5e73\u53f0\u5efa\u8bbe\u63a8\u8fdb\u4f1a\uff0c\u7b7e\u7ea6\u548c\u5f00\u5de5\u9879\u76ee\u603b\u6295\u8d44\u8d85840\u4ebf\u5143\u3002\u5305\u62ec\u5965\u6cf0\u751f\u7269\u5e74\u4ea7\u4f53\u5916\u8bca\u65ad\u8bd5\u5242\u751f\u4ea7\u4e2d\u5fc3\u3001\u8054\u5ddd\u751f\u7269\u7684\u57fa\u56e0\u6355\u83b7\u79d1\u6280\u7814\u7a76\u9662\u3001\u57fa\u56e0\u68c0\u6d4b\u8bd5\u5242\u76d2GMP\u751f\u4ea7\u57fa\u5730\u7b49\u9879\u76ee\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u9752\u5c9b\u65b0\u751f\u513f\u514d\u8d39\u5168\u57fa\u56e0\u68c0\u6d4b\u9879\u76ee<\/div>\n
\u53d6\u5f97\u9636\u6bb5\u6027\u6210\u679c<\/div>\n
\u65e5\u524d\uff0c\u7531\u9752\u5c9b\u897f\u6d77\u5cb8\u65b0\u533a\u536b\u751f\u5065\u5eb7\u5c40\u7275\u5934\u3001\u9752\u5c9b\u897f\u6d77\u5cb8\u65b0\u533a\u533a\u8d22\u653f\u652f\u6301\u7684\u6c11\u751f\u9879\u76ee\u2014\u2014\u9752\u5c9b\u897f\u6d77\u5cb8\u65b0\u533a\u65b0\u751f\u513f\u514d\u8d39\u5168\u57fa\u56e0\u7ec4\u68c0\u6d4b\u9879\u76ee\uff0c\u8ba1\u5212\u5728\u4e00\u5e74\u5185\u4e3a\u9752\u5c9b\u897f\u6d77\u5cb8\u65b0\u533a\u7b26\u5408\u7b5b\u67e5\u6761\u4ef6\u76841\u4e07\u540d\u5b69\u5b50\u63d0\u4f9b\u57fa\u4e8e\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6280\u672f\u7684353\u9879\u68c0\u6d4b\u3002\u8be5\u9879\u76ee\u81ea6\u670828\u65e5\u4ee5\u6765\uff0c\u5408\u8ba1\u7d2f\u8ba1\u91c7\u68371796\u4f8b\u3002<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u53d1\u5c55<\/div>\n
\u00a0<\/div>\n
\u25a0 13\u5bb6\u4f01\u4e1a\u878d\u8d44\u4fe1\u606f<\/div>\n
\u8be6\u60c5\u5c06\u66f4\u65b0\u5728\u57fa\u56e0\u6167\u6570\u636e\u5e93<\/div>\n
www.yourmap.net.cn<\/div>\n\n
\n
\"RmFicvQBAkgDyicjblSMgHhWSU33auHMh0FaAftKW2Z7ehok3Rn0YRC6mbkV4evEmpBnb7cuKKqQ7joaCZiaIgJSQ\"\/<\/figure><\/div>\n\n
\u4f01\u4e1a\u878d\u8d44\u4fe1\u606f\uff08\u5236\u8868\/\u57fa\u56e0\u6167\uff09<\/div>\n
\u8fd1\u671f\u56fd\u5185\u5916\u53d1\u5e03\u878d\u8d44\u52a8\u6001\u7684\u4f01\u4e1a\u6709\uff0c\u5fae\u8fdc\u57fa\u56e0\u3001\u6d3e\u771f\u751f\u7269\u3001\u5609\u5b9d\u4ec1\u548c\u3001\u767e\u5965\u6cf0\u3001\u8d5e\u8363\u533b\u836f\u3001\u8446\u5143\u533b\u836f\u3001\u8d5b\u79d1\u5e0c\u5fb7\u3001Encoded Therapeutics\u3001Mission Bio\u3001Dyne Therapeutics\u3001Inozyme Pharma\u3001Micronoma\u3001Scailyte\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a08\u5bb6\u4e0a\u5e02\u4f01\u4e1aQ2\u8d22\u62a5<\/div>\n
1\uff09Illumina Q2\u6536\u5165\u540c\u6bd4\u4e0b\u964d25%\uff0c\u4e3b\u8981\u662f\u65b0\u51a0\u80ba\u708e\u75ab\u60c5\u5f71\u54cd\u4e86\u5176\u79d1\u7814\u5ba2\u6237\u3002\u5176\u4e2d\uff0c\u82af\u7247\u4e1a\u52a1\u7684\u603b\u6536\u5165\u540c\u6bd4\u4e0b\u964d39%\uff1b\u670d\u52a1\u53ca\u5176\u4ed6\u6536\u5165\u540c\u6bd4\u4e0b\u964d\u4e8621\uff05\uff1b<\/div>\n
2\uff09Thermo Fisher Q2\u603b\u6536\u5165\u4e3a69.2\u4ebf\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957f9.5\uff05\u3002\u6574\u4f53\u89e3\u51b3\u65b9\u6848\u90e8\u95e8\u7684\u6536\u5165\u540c\u6bd4\u589e\u957f52.2\uff05\uff0c\u800c\u5206\u6790\u4eea\u5668\u90e8\u95e8\u7684\u9500\u552e\u989d\u4e0b\u964d\u4e8620.6\uff05\uff1b<\/div>\n
3\uff09Bionano Genomics\u62a5\u544a\u663e\u793a\u5176Q2\u6536\u5165\u4e0b\u964d\u4e8646\uff05\uff1b<\/div>\n
4\uff09PacBio Q2\u603b\u6536\u5165\u540c\u6bd4\u4e0b\u964d30.5\uff05\uff0c\u7531\u4e8eCOVID-19\u7684\u5f71\u54cd\uff0c\u5176\u4e24\u4e2a\u4e3b\u8981\u4e1a\u52a1\u90e8\u95e8\u7684\u6536\u5165\u5747\u4e0b\u964d\uff1b<\/div>\n
5\uff0910x Genomics Q2\u6536\u5165\u540c\u6bd4\u4e0b\u964d23%\uff1b<\/div>\n
6\uff09Guardant\u00a0Q2\u9500\u552e\u6536\u51656634\u4e07\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957f23%\uff1b<\/div>\n
7\uff09\u6cdb\u751f\u5b50Q2\u603b\u8425\u65361.017\u4ebf\u5143\uff0c\u540c\u6bd4\u589e\u957f40.3%\uff0c\u5176\u4e2d\u8bca\u65ad\u548c\u76d1\u6d4b\u4e1a\u52a1\u540c\u6bd4\u589e\u957f52.1%\uff1b<\/div>\n
8\uff09\u71c3\u77f3\u533b\u5b66Q2\u603b\u8425\u6536\u4e3a1.74\u4ebf\u5143\uff0c\u540c\u6bd4\u589e\u957f26.1%\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u5b57\u8282\u8df3\u52a85\u4ebf\u5143\u6536\u8d2d\u767e\u79d1\u540d\u533b<\/div>\n
8\u670812\u65e5\uff0c\u5b57\u8282\u8df3\u52a8\u4ee55\u4ebf\u5143\u5bf9\u4ef7\u5b8c\u6210\u5bf9\u767e\u79d1\u540d\u533b\u7684\u5168\u8d44\u6536\u8d2d\uff0c\u5b57\u8282\u8df3\u52a8\u8868\u793a\uff0c\u6536\u8d2d\u767e\u79d1\u540d\u533b\u4e3b\u8981\u662f\u4e3a\u4e86\u5efa\u8bbe\u66f4\u5b8c\u6574\u7684\u5e73\u53f0\u5185\u5bb9\u751f\u6001\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0Seres\u80a0\u9053\u5fae\u751f\u7269\u7597\u6cd5\u4e09\u671f\u4e34\u5e8a\u6210\u529f<\/div>\n
8\u670810\u65e5\uff0cSeres Therapeutics\u5ba3\u5e03\u5176\u80a0\u9053\u5fae\u751f\u7269\u7597\u6cd5SER-109\u6cbb\u7597\u8270\u96be\u68ad\u83cc\u611f\u67d3\u76843\u671f\u4e34\u5e8a\u6700\u65b0\u6570\u636e\uff1a\u590d\u53d1\u7387\u964d\u4f4e30.2%\uff0c\u964d\u4f4e\u590d\u53d1\u98ce\u966973%\uff08HR=0.27\uff09\u3002Seres Therapeutics\u80a1\u4ef7\u5f53\u5929\u4e0a\u6da8\u8fd1400%\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0Seventure\u8ba1\u5212\u518d\u5411\u5fae\u751f\u7269\u7ec4\u6295\u8fd160\u4ebf\u7f8e\u5143<\/div>\n
\u8fd1\u65e5\uff0c\u6b27\u6d32\u98ce\u9669\u6295\u8d44\u673a\u6784 Seventure Partner \u5ba3\u5e03\uff0c\u5176\u65d7\u4e0b Health for Life Capital\uff08HFL\uff09 II \u671f\u57fa\u91d1\u83b7\u6279\u6210\u7acb\uff0c\u529b\u4e89\u5728 2022 \u5e74\u5e95\u524d\u4e3a\u5fae\u751f\u7269\u7ec4\u9886\u57df\u7684\u521b\u65b0\u578b\u516c\u53f8\u63d0\u4f9b 50 \u4ebf\u6b27\u5143\uff08\u7ea6\u5408 58.9 \u4ebf\u7f8e\u5143\uff09\u7684\u878d\u8d44\u652f\u6301\uff0c\u5c24\u5176\u662f\u5317\u7f8e\u3001\u6b27\u6d32\u3001\u4e9a\u6d32\u548c\u4ee5\u8272\u5217\u7b49\u5730\u7684\u516c\u53f8\u3002<\/div>\n
\u62d3\u5c55\u9605\u8bfb>><\/div>\n
Science\u516c\u5e03\u5fae\u751f\u7269\u7ec4\u5927\u5956\uff0c\u4e09\u5927\u6210\u679c\u503c\u5f97\u5173\u6ce8<\/a><\/div>\n
\u00a0<\/div>\n
\u79d1\u7814\u8fdb\u5c55<\/div>\n
\u25a0 43\u4e07\u4f59\u4f8b\u57fa\u56e0\u5927\u6570\u636e\u7814\u7a76<\/div>\n
\u9610\u660e\u94f6\u5c51\u75c5\u4e0e\u9aa8\u8d28\u758f\u677e\u7684\u5173\u7cfb<\/div>\n
8\u67081\u65e5\uff0c\u98ce\u6e7f\u75c5\u5e74\u9274\uff08Annals of the Rheumatic Diseases\uff09\u4e0a\u4e00\u7bc7\u7814\u7a76\u6587\u7ae0\uff0c\u9610\u660e\u4e86\u94f6\u5c51\u75c5\uff08\u4fd7\u79f0\u725b\u76ae\u7663\uff09\u53ca\u94f6\u5c51\u75c5\u6027\u5173\u8282\u708e\u4e0e\u9aa8\u8d28\u758f\u677e\u95f4\u7684\u5173\u7cfb\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/dx.doi.org\/10.1136\/annrheumdis-2020-217892<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u4e73\u817a\u764c\u4e2d\u53d1\u73b0\u201c\u56db\u94feDNA\u7ed3\u6784\u201d<\/div>\n
\u6216\u53ef\u7528\u4f5c\u764c\u75c7\u5206\u578b\u548c\u6cbb\u7597\u9776\u6807<\/div>\n
\u8fd1\u65e5\uff0c\u82f1\u56fd\u5251\u6865\u5927\u5b66\u7814\u7a76\u56e2\u961f\u9996\u6b21\u5728\u4e73\u817a\u764c\u7ec4\u7ec7\u4e2d\u53d1\u73b0\u4e86G4\uff08G4-DNA\uff0c\u4e00\u79cd\u7531\u5bcc\u542b\u9e1f\u560c\u5464\u7684\u6838\u9178\u5e8f\u5217\u6240\u6784\u6210\u7684\u56db\u80a1\u578b\u6001\uff09\u7ed3\u6784\u7684\u5b58\u5728\uff0c\u6216\u53ef\u7528\u4e8e\u786e\u5b9a\u4e73\u817a\u764c\u4e9a\u578b\uff0c\u5e76\u8bc1\u5b9e\u5176\u4e30\u5ea6\u548c\u5f62\u6210\u4f4d\u7f6e\u5728\u67d0\u4e9b\u7c7b\u578b\u7684\u4e73\u817a\u764c\u4e2d\u8d77\u91cd\u8981\u4f5c\u7528\uff0c\u4e3a\u4e73\u817a\u764c\u4e2a\u6027\u5316\u6cbb\u7597\u63d0\u4f9b\u4e86\u6f5c\u5728\u7684\u65b0\u9776\u6807\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41588-020-0672-8<\/div>\n
\u00a0<\/div>\n
\u25a0 \u53d1\u73b0\u5f31\u7578\u7cbe\u5b50\u75c7\u81f4\u75c5\u65b0\u57fa\u56e0<\/div>\n
8\u670812\u65e5\uff0c\u56fd\u5185\u7814\u7a76\u56e2\u961f\u901a\u8fc7\u5bf990\u4f8b\u6c49\u65cf\u7537\u6027MMAF\uff08\u7cbe\u5b50\u97ad\u6bdb\u591a\u53d1\u5f62\u6001\u5f02\u5e38\uff09\u60a3\u8005\u8fdb\u884c\u57fa\u56e0\u68c0\u6d4b\u548c\u9057\u4f20\u5b66\u5206\u6790\uff0c\u53d1\u73b0\u5e76\u9274\u5b9a\u4e86\u5f31\u7578\u7cbe\u5b50\u75c7\u65b0\u7684\u81f4\u75c5\u57fa\u56e0CFAP58\uff0c\u8be5\u57fa\u56e0\u7684\u53cc\u7b49\u4f4d\u7a81\u53d8\u5bfc\u81f4\u7537\u6027\u4e0d\u80b2\u548c\u96c4\u6027\u5c0f\u9f20\u4e0d\u80b2\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1016\/j.ajhg.2020.07.010<\/div>\n
\u00a0<\/div>\n
\u25a0 16\u6b3e\u6d4b\u5e8f\u5e73\u53f0\u6027\u80fd\u6bd4\u8f83\u6210\u679c\u53d1\u5e03<\/div>\n
\u8fd1\u65e5\uff0c\u7531\u751f\u7269\u5206\u5b50\u8d44\u6e90\u8bbe\u65bd\u534f\u4f1a\uff08ARBF\uff09\u652f\u6301\u7684ABRF NGS II\u671f\u7814\u7a76\u6210\u679c\u53d1\u5e03\u4e8e\u9884\u5370\u672c\u5e73\u53f0BioRxiv\u3002\u6b64\u7814\u7a76\u5206\u6790\u4e86\u5728\u6587\u5e93\u5236\u5907\u548c\u751f\u7269\u4fe1\u606f\u53ef\u63a7\u4e0b\uff0c \u5404\u5927\u6d4b\u5e8f\u5e73\u53f0\u7684\u6570\u636e\uff0c\u5c06\u5e73\u53f0\u7684\u6027\u80fd\u548c\u6d4b\u5e8f\u9519\u8bef\u6a21\u5f0f\u4e00\u4e00\u63ed\u793a\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1101\/2020.07.23.218602<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u5355\u7ec6\u80de\u6d4b\u5e8f\u534a\u76d1\u7763\u6df1\u5ea6\u5b66\u4e60\u7b97\u6cd5\u53d1\u5e03<\/div>\n
\u8fd1\u65e5\uff0c\u4e2d\u5927\u4e2d\u5c71\u773c\u79d1\u4e2d\u5fc3\u8c22\u5fd7\u8bfe\u9898\u7ec4\u5f00\u53d1\u4e86DISC\u2014\u2014\u57fa\u4e8e\u534a\u76d1\u7763\u5b66\u4e60\u65b9\u5f0f\u7684\u6df1\u5ea6\u5b66\u4e60\u7f51\u7edc\uff0c\u7528\u4e8e\u89e3\u51b3\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6d4b\u5e8fdropouts\u95ee\u9898\u3002\u901a\u8fc7DISC\u53ef\u63a8\u65ad\u51fa\u88ab\u626d\u66f2\u4e86\u8868\u8fbe\u4e0e\u7ed3\u6784\u57fa\u56e0\u7684\u771f\u5b9e\u60c5\u51b5\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/genomebiology.biomedcentral.com\/articles\/10.1186\/s13059-020-02083-3<\/div>\n
\u00a0<\/div>\n
\u25a0 \u53d1\u73b0\u6291\u5236\u80bf\u7624\u7684\u65b0\u57fa\u56e0<\/div>\n
\u6700\u8fd1\uff0c\u56fd\u5916\u56e2\u961f\u7814\u7a76\u53d1\u73b0\u4e0e\u80bf\u7624\u81ea\u884c\u6d88\u9000\u6709\u5173\u7684\u53d8\u5f02\u57fa\u56e0RASL11A\u3002\u5982\u679c\u989d\u5916\u589e\u52a0RASL116\u7684\u8868\u8fbe\uff0c\u53ef\u4ee5\u51cf\u7f13\u80bf\u7624\u7ec6\u80de\u751f\u957f\u3002\u7814\u7a76\u4eba\u5458\u8ba4\u4e3a\uff0cRASL11A\u5177\u6709\u80bf\u7624\u6291\u5236\u7684\u5929\u7136\u673a\u5236\u4ee5\u53ca\u4f5c\u4e3a\u764c\u75c7\u6cbb\u7597\u9776\u70b9\u7684\u6f5c\u529b\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/439549a<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u65b0\u751f\u513fWES\u534f\u52a9\u7b5b\u67e5\u5148\u5929\u6027\u9057\u4f20\u4ee3\u8c22\u7f3a\u9677\u75c5<\/div>\n
\u8fd1\u65e5\uff0c\u56fd\u5916\u56e2\u961f\u53d1\u8868\u4e8eNature Medicine\u4e00\u9879\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u5bf9\u65b0\u751f\u513f\u5e72\u8840\u6ee4\u7eb8\u7247\u6837\u672c\u8fdb\u884c\u5916\u663e\u5b50\u7ec4\u6d4b\u5e8f\uff08WES\uff09\u5177\u6709\u53d1\u73b0\u5148\u5929\u6027\u9057\u4f20\u4ee3\u8c22\u7f3a\u9677\u75c5\u7684\u6f5c\u529b\uff0c\u5176\u65b9\u5f0f\u53ef\u8865\u5145\u57fa\u4e8e\u4f20\u7edf\u8d28\u8c31\u6280\u672f\u7684\u65b0\u751f\u513f\u7b5b\u67e5\u65b9\u6848\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41591-020-0966-5<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u7535\u955c\u6807\u8bb0\u6280\u672f\u5b9e\u73b0\u7ec6\u80de\u4e2d\u7684\u5355\u5206\u5b50\u5b9a\u4f4d<\/div>\n
\u8fd1\u65e5\uff0c\u5317\u4eac\u751f\u547d\u79d1\u5b66\u7814\u7a76\u6240\u56e2\u961f\u539f\u521b\u6027\u5730\u5f00\u53d1\u4e86\u4e00\u79cd\u65b0\u578b\u514b\u9686\u7535\u955c\u6807\u8bb0\u6280\u672f\uff0c\u8be5\u6280\u672f\u53ef\u5b9e\u73b0\u7ec6\u80de\u8d85\u5fae\u7ed3\u6784\u4e0a\u5355\u5206\u5b50\u6c34\u5e73\u7684\u7cbe\u786e\u8bc6\u522b\u4e0e\u5b9a\u4f4d\uff0c\u4e3a\u7ec6\u80de\u7684\u7535\u955c\u8d85\u5fae\u7ed3\u6784\u5355\u5206\u5b50\u6c34\u5e73\u7814\u7a76\u63d0\u4f9b\u4e86\u65b0\u5de5\u5177\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41592-020-0911-z<\/div>\n
\u6700\u65b0\u4f1a\u8bae<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u7b2c\u4e5d\u5c4a\u5168\u56fd\u751f\u7269\u4fe1\u606f\u5b66\u4e0e\u7cfb\u7edf\u751f\u7269\u5b66\u5b66\u672f\u5927\u4f1a<\/div>\n
2020\u5e7410\u67088\u65e5~11\u65e5\uff0c\u7b2c\u4e5d\u5c4a\u5168\u56fd\u751f\u7269\u4fe1\u606f\u5b66\u4e0e\u7cfb\u7edf\u751f\u7269\u5b66\u5b66\u672f\u5927\u4f1a\u5c06\u4e8e\u82cf\u5dde\u91d1\u9e21\u6e56\u56fd\u9645\u535a\u89c8\u4e2d\u5fc3\u53ec\u5f00\u3002\u5927\u4f1a\u7531\u4e2d\u56fd\u751f\u7269\u4fe1\u606f\u5b66\u5b66\u4f1a\u8054\u5408\u4f53\u4e3b\u529e\uff0c\u540c\u6d4e\u5927\u5b66\u3001\u590d\u65e6\u5927\u5b66\u627f\u529e\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a02020CSCO\u4e34\u5e8a\u80bf\u7624\u5b66\u5927\u4f1a<\/div>\n
\u7b2c23\u5c4a\u5168\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u5927\u4f1a\u66a82020\u5e74CSCO\u5927\u4f1a\u5c06\u4e8e9\u670819\u65e5-26\u65e5\u53ec\u5f00\u3002\u5927\u4f1a\u5c06\u91c7\u53d6\u7f51\u7edc\u76f4\u64ad\u5f62\u5f0f\uff0c\u4e8e\u5317\u4eac\u3001\u4e0a\u6d77\u3001\u5e7f\u5dde\u3001\u54c8\u5c14\u6ee8\u3001\u6b66\u6c49\u8bbe\u7f6e\u4e13\u5bb6\u6f14\u8bb2\u4f1a\u573a\u3002\u57fa\u56e0\u6167\u5c4a\u65f6\u5c06\u6df1\u5ea6\u62a5\u9053\u76f8\u5173\u70ed\u70b9\u8d44\u8baf\u53ca\u4e13\u8bbf\uff0c\u6b22\u8fce\u5173\u6ce8\u540e\u7eed\u62a5\u9053\u53ca\u5546\u52a1\u5408\u4f5c\u3002<\/div>\n
\u62d3\u5c55\u9605\u8bfb>><\/div>\n
CSCO\u00a0| \u7ea6150\u573a\u4f1a\u8bae\u5730\u56fe\uff0c\u7528\u6570\u636e\u544a\u8bc9\u4f60\u70ed\u5ea6<\/a><\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0CCO\u4e2d\u56fd\u80bf\u7624\u5b66\u5927\u4f1a<\/div>\n
2020\u5e7411\u670812\u65e5-15\u65e5\uff0c\u7531\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u4e3b\u529e\uff0c\u4e2d\u5c71\u5927\u5b66\u80bf\u7624\u9632\u6cbb\u4e2d\u5fc3\u3001\u5e7f\u4e1c\u7701\u6297\u764c\u534f\u4f1a\u627f\u529e\uff0c\u56fd\u9645\u6297\u764c\u8054\u76df\uff08UICC\uff09\u3001\u4e2d\u56fd\u6574\u5408\u533b\u5b66\u53d1\u5c55\u6218\u7565\u7814\u7a76\u9662\u534f\u529e\u76842020\u4e2d\u56fd\u80bf\u7624\u5b66\u5927\u4f1a\uff08CCO\uff09\u5c06\u5728\u5e7f\u5dde\u53ec\u5f00\u3002\u672c\u6b21\u5927\u4f1a\u4e3b\u9898\u4e3a\u201c\u80bf\u7624\u9632\u6cbb\uff0c\u8d62\u5728\u6574\u5408\u201d\u3002<\/div>\n
\u00a0<\/div>\n
\u25a0\u00a02020\u7f55\u89c1\u75c5\u5408\u4f5c\u4ea4\u6d41\u4f1a\u62a5\u540d\u5f00\u542f<\/div>\n
8\u670822\u65e5-23\u65e5\uff0c\u75c5\u75db\u6311\u6218\u57fa\u91d1\u4f1a\u5c06\u5728\u5317\u4eac\u4e3b\u529e2020\u7f55\u89c1\u75c5\u5408\u4f5c\u4ea4\u6d41\u4f1a\u3002\u5927\u4f1a\u4ee5\u4e2d\u56fd\u7f55\u89c1\u75c5\u8054\u76df\u4f5c\u4e3a\u6307\u5bfc\u5355\u4f4d\uff0c\u5c71\u4e1c\u7701\u7acb\u533b\u9662\u3001\u74f7\u5a03\u5a03\u7f55\u89c1\u75c5\u5173\u7231\u4e2d\u5fc3\u3001\u4e2d\u56fd\u6208\u8c22\u75c5\u534f\u4f1a\u7b499\u5bb6\u7ec4\u7ec7\u4e3a\u534f\u529e\u5355\u4f4d\u3002\u536b\u5065\u59d4\u7f55\u89c1\u75c5\u8bca\u7597\u4e13\u59d4\u4f1a\u4e3b\u4efb\u5f20\u6292\u626c\uff0c\u4e2d\u56fd\u7f55\u89c1\u75c5\u8054\u76df\u6267\u884c\u7406\u4e8b\u957f\u674e\u6797\u5eb7\u7b4924\u4f4d\u5609\u5bbe\u62df\u53c2\u4f1a\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>\u5173\u6ce8\u7f55\u89c1\u75c5\u7fa4\u4f53\uff0c\u5171\u5546\u8bca\u7597\u53ef\u53ca\u6027<\/a><\/div>\n
\u00a0<\/div>\n
\u25a0\u00a0\u7b2c\u5341\u4e94\u5c4a\u56fd\u9645\u57fa\u56e0\u7ec4\u5b66\u5927\u4f1a\uff08ICG-15\uff09\u5c06\u53ec\u5f00<\/div>\n
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