{"id":9033,"date":"2020-09-21T01:00:13","date_gmt":"2020-09-20T17:00:13","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100016087&idx=1&sn=1b6819ccac29a5a3924581666796bf1d&chksm=6b714d605c06c476e48660401e3de64406faa265d80bb5ba412074f565b2e53dc76041c0c266#rd"},"modified":"2026-04-02T09:06:34","modified_gmt":"2026-04-02T01:06:34","slug":"535351","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2020\/09\/21\/535351\/","title":{"rendered":"\u5468\u62a5\u4e28\u6700\u65b0\u7248\u65b0\u51a0\u9632\u63a7\u65b9\u6848\u589e\u52a0\u57fa\u56e0\u6d4b\u5e8f\u6eaf\u6e90\u5185\u5bb9\uff0cCDE\u5f15\u5bfc\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u7814\u7a76\u4e0e\u7533\u62a5"},"content":{"rendered":"

<\/p>\n

\u6570\u5b57\u751f\u547d\u5065\u5eb7\u5468\u62a5GeneMail<\/div>\n
113\u671f<\/div>\n
\u6587\u7ae0 | \u57fa\u56e0\u6167\u7f16\u8f91 | Shawne<\/div>\n
\n\n
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\"RmFicvQBAkgAuicYOpycUdBxZFuHkE6C9ZWgldP8LO28WPZrDP0EmpicT1iaYZyzF5zxglR7E93zQTcydr5Rib6VOibw\"\/<\/figure><\/div>\n\n
\u65b0\u51a0\u75c5\u6bd2\u5168\u75c5\u6bd2\u4e09\u7ef4\u7cbe\u7ec6\u7ed3\u6784\u53ca\u6838\u7cd6\u6838\u86cb\u767d\u590d\u5408\u7269\u7684\u5206\u5b50\u7ec4\u88c5\uff08\u56fe\u6e90\/Cell\uff09<\/div>\n
01\u00a0\u5934\u6761<\/div>\n
\u2756\u00a0\u6700\u65b0\u7248\u65b0\u51a0\u9632\u63a7\u65b9\u6848\u589e\u52a0\u57fa\u56e0\u6d4b\u5e8f\u6eaf\u6e90\u5185\u5bb9<\/div>\n
\u65e5\u524d\uff0c\u56fd\u52a1\u9662\u5e94\u5bf9\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u80ba\u708e\u75ab\u60c5\u8054\u9632\u8054\u63a7\u673a\u5236\u7efc\u5408\u7ec4\u5370\u53d1\u4e86\u7b2c\u4e03\u7248\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u80ba\u708e\u9632\u63a7\u65b9\u6848\uff0c\u5176\u4e2d\u4e00\u9879\u4fee\u8ba2\u5185\u5bb9\u662f\u5728\u6807\u672c\u91c7\u96c6\u548c\u5b9e\u9a8c\u5ba4\u68c0\u6d4b\u65b9\u9762\uff0c\u589e\u52a0\u4e86\u57fa\u56e0\u6d4b\u5e8f\u5185\u5bb9\uff1b\u5e76\u4e14\u8981\u6c42\u5404\u5730\u53d1\u751f\u7684\u9996\u4f8b\u548c\u611f\u67d3\u6765\u6e90\u4e0d\u660e\u7684\u75c5\u4f8b\u4ee5\u53ca\u73af\u5883\u76d1\u6d4b\u53d1\u73b0\u7684\u9633\u6027\u6807\u672c\uff0c\u5e94\u5f53\u5f00\u5c55\u57fa\u56e0\u6d4b\u5e8f\u7b49\u6eaf\u6e90\u5de5\u4f5c\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.nhc.gov.cn\/jkj\/s3577\/202009\/318683cbfaee4191aee29cd774b19d8d.shtml<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0CDE\u5f15\u5bfc\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u7814\u7a76\u4e0e\u7533\u62a5<\/div>\n
9\u670814\u65e5\uff0c\u4e3a\u89c4\u8303\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u7684\u836f\u5b66\u7814\u7a76\uff0c\u5f15\u5bfc\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u7684\u7814\u7a76\u4e0e\u7533\u62a5\uff0cCDE\u5728\u501f\u9274\u56fd\u5185\u5916\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u76d1\u7ba1\u6807\u51c6\u7684\u57fa\u7840\u4e0a\uff0c\u5f62\u6210\u4e86\u300a\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u836f\u5b66\u7814\u7a76\u4e0e\u8bc4\u4ef7\u6280\u672f\u6307\u5bfc\u539f\u5219\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b\uff0c\u516c\u5f00\u5f81\u6c42\u610f\u89c1\u65f6\u95f4\u622a\u81f32020\u5e7410\u670813\u65e5\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.cde.org.cn\/news.do?method=viewInfoCommon&id=b167edc6058fc23e<\/div>\n
\u00a0<\/div>\n
\u6700\u65b0\u300a\u7ec6\u80de\u6cbb\u7597\u548c\u57fa\u56e0\u6cbb\u7597\u884c\u7814\u62a5\u544a\u300b<\/div>\n
\u00a0\u542f\u52a8\u62db\u5546\u51a0\u540d\u5408\u4f5c<\/div>\n\n
\n
\"RmFicvQBAkgCwpibd4YnaAkAjuazKyR0FcSfibMDQ2o510AXTv7ialXG1tDkRwmhpEU42BbUa9sXIXKx7hmjKPJLCw\"\/<\/figure><\/div>\n\n
02\u00a0\u653f\u7b56<\/div>\n
\u2756\u00a02020\u6700\u65b0\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\u8c03\u6574<\/div>\n
9\u670818\u65e5\uff0c\u56fd\u5bb6\u533b\u4fdd\u5c40\u5b98\u7f51\u516c\u793a\u300a2020\u5e74\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\u8c03\u6574\u901a\u8fc7\u5f62\u5f0f\u5ba1\u67e5\u7684\u7533\u62a5\u836f\u54c1\u540d\u5355\u300b\uff0c\u516c\u793a\u671f1\u5468\uff0c\u8bf7\u793e\u4f1a\u5404\u754c\u5bf9\u516c\u793a\u836f\u54c1\u7684\u8d44\u683c\u6761\u4ef6\u53ca\u5f62\u5f0f\u5ba1\u67e5\u7ed3\u679c\u8fdb\u884c\u76d1\u7763\u3002\u7533\u62a5\u4f01\u4e1a\u53ef\u767b\u9646\u201c2020\u5e74\u56fd\u5bb6\u533b\u4fdd\u836f\u54c1\u76ee\u5f55\u8c03\u6574\u7533\u62a5\u7cfb\u7edf\u201d\u67e5\u8be2\u81ea\u5df1\u6240\u7533\u62a5\u836f\u54c1\u7684\u5f62\u5f0f\u5ba1\u67e5\u7ed3\u679c\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.cnpharm.com\/upload\/resources\/file\/2020\/09\/19\/66766.pdf<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4e60\u8fd1\u5e73\u53d1\u6587<\/div>\n
\u52a0\u5feb\u8865\u9f50\u751f\u547d\u79d1\u5b66\u3001\u751f\u7269\u6280\u672f\u7b49\u9886\u57df\u7684\u77ed\u677f<\/div>\n
9\u670816\u65e5\uff0c\u4e60\u8fd1\u5e73\u603b\u4e66\u8bb0\u53d1\u8868\u91cd\u8981\u6587\u7ae0\u300a\u6784\u5efa\u8d77\u5f3a\u5927\u7684\u516c\u5171\u536b\u751f\u4f53\u7cfb\uff0c\u4e3a\u7ef4\u62a4\u4eba\u6c11\u5065\u5eb7\u63d0\u4f9b\u6709\u529b\u4fdd\u969c\u300b\u3002\u6587\u7ae0\u5f3a\u8c03\uff0c\u8981\u52a0\u5927\u536b\u751f\u5065\u5eb7\u9886\u57df\u79d1\u6280\u6295\u5165\uff0c\u53d1\u6325\u65b0\u578b\u4e3e\u56fd\u4f53\u5236\u7684\u4f18\u52bf\uff0c\u96c6\u4e2d\u529b\u91cf\u5f00\u5c55\u6838\u5fc3\u6280\u672f\u653b\u5173\uff0c\u6301\u7eed\u52a0\u5927\u91cd\u5927\u75ab\u75c5\u9632\u6cbb\u7ecf\u8d39\u6295\u5165\uff0c\u52a0\u5feb\u8865\u9f50\u6211\u56fd\u5728\u751f\u547d\u79d1\u5b66\u3001\u751f\u7269\u6280\u672f\u3001\u533b\u836f\u536b\u751f\u3001\u533b\u7597\u8bbe\u5907\u7b49\u9886\u57df\u7684\u77ed\u677f\u3002<\/div>\n
\u00a0<\/div>\n
03\u00a0\u4ea7\u4e1a<\/div>\n
\u2756\u00a0\u4e0a\u5468\u4f01\u4e1a\u878d\u8d44\u4fe1\u606f<\/div>\n\n
\n
\"RmFicvQBAkgAM8lp8nWWicQzD7QcaY3lic1DesMmhS3NB4NL6gU9NagZQx5xjjLUh4OG54cMg23rvNw9CicbU0Bd3Q\"\/<\/figure><\/div>\n\n
\u8fd1\u671f\u56fd\u5185\u5916\u53d1\u5e03\u878d\u8d44\u52a8\u6001\u4f01\u4e1a\u5305\u62ec\u5854\u5409\u745e\u751f\u7269\u3001\u5c1a\u5065\u751f\u7269\u3001LAVA Therapeutics \u3001ESCAPE Bio\u3001Ansa Biotechnologies\u3001Neogene Therapeutics\u3001Cardea Bio \u548cHexagon Bio\u3002<\/div>\n
\u00a0<\/div>\n
\u2756 Illumina\u900f\u973280\u4ebf\u7f8e\u5143\u6536\u8d2dGrial<\/div>\n
\u80a1\u4ef7\u5e94\u58f0\u4e0b\u8dcc10%<\/div>\n
\u7f8e\u56fd\u65f6\u95f49\u670816\u65e5\uff0c\u636e\u5916\u5a92\u62a5\u9053\uff0cIllumina\u6b63\u5728\u4e0e\u80bf\u7624\u65e9\u7b5b\u4f01\u4e1aGrail\u6d3d\u8c08\u6536\u8d2d\u8ba1\u5212\uff0c\u53ef\u80fd\u4f1a\u4ee5 80 \u4ebf\u7f8e\u5143\u7684\u4ef7\u683c\u6536\u8d2dGrail\u3002\u8be5\u4ea4\u6613\u8fbe\u6210\uff0c\u5c06\u4f1a\u662fIllumina\u53f2\u4e0a\u6700\u5927\u7684\u5e76\u8d2d\u6848\u3002\u5728\u5ba3\u5e03\u6d88\u606f\u4e4b\u540e\uff0cIllumina\u7684\u80a1\u7968\u5373\u523b\u4e0b\u8dcc\u7ea610\uff05\u3002<\/div>\n
\u3010\u7f16\u8005\u8bed\u3011Illumina\u5b75\u5316\u51faGrail\uff0c\u201c\u5265\u79bb\u201d\u540e\u5728Grail\u4e0a\u5e02\u4e4b\u524d\u900f\u9732\u6536\u8d2d\u6d88\u606f\uff0c\u53ef\u80fd\u4e0e\u7b2c\u4e8c\u5b63\u5ea6\u4f4e\u8ff7\u8d22\u62a5\u6709\u5173\uff0c\u4ece\u5e02\u573a\u53cd\u5e94\u770b\u4e0d\u7b26\u5408\u4ef7\u503c\u94fe\u6301\u7eed\u589e\u957f\u3002\u5e02\u573a\u5bf9\u4e0a\u6e38\u4f01\u4e1a\u201c\u67d3\u6307\u201d\u4e2d\u4e0b\u6e38\u7684\u53cd\u5e94\uff0c\u503c\u5f97\u56fd\u5185\u5934\u90e8\u4f01\u4e1a\u53cd\u601d\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u9996\u4e2a\u9ad8\u901a\u91cf\u6d4b\u5e8f\u4eea\u6807\u51c6\u53d1\u5e03<\/div>\n
9\u670815\u65e5\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6b63\u5f0f\u53d1\u5e03\u56fd\u5185\u9996\u4e2a\u533b\u7597\u5668\u68b0\u884c\u4e1a\u57fa\u56e0\u6d4b\u5e8f\u4eea\u6807\u51c6\u2014\u2014\u300a\u9ad8\u901a\u91cf\u6d4b\u5e8f\u4eea\u6807\u51c6\u300b\uff08\u6807\u51c6\u7f16\u53f7\uff1aYY\/T 1723-2020\uff09\uff0c\u8fd9\u662f\u5168\u7403\u9996\u6b21\u9488\u5bf9\u57fa\u56e0\u6d4b\u5e8f\u4eea\u8bbe\u5b9a\u6807\u51c6\u3002\u5185\u5bb9\u5305\u62ec\u9ad8\u901a\u91cf\u6d4b\u5e8f\u4eea\u7684\u8303\u56f4\u3001\u89c4\u8303\u6027\u5f15\u7528\u6587\u4ef6\u3001\u5206\u7c7b\u3001\u8981\u6c42\u3001\u8bd5\u9a8c\u65b9\u6cd5\u3001\u6807\u7b7e\u548c\u4f7f\u7528\u8bf4\u660e\u4e66\u3001\u5305\u88c5\u3001\u8fd0\u8f93\u3001\u8d2e\u5b58\u3001\u53c2\u8003\u6587\u732e\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u9996\u4e2a\u76ae\u4e0b\u6ce8\u5c04PD-L1\u5728\u4e2d\u56fd\u62df\u4f18\u5148\u5ba1\u8bc4<\/div>\n
9\u670817\u65e5\uff0cCDE\u516c\u793a\u4fe1\u606f\u663e\u793a\uff0c\u7531\u601d\u8def\u8fea\u548c\u5eb7\u5b81\u6770\u745e\u5171\u540c\u5f00\u53d1\u7684\u6069\u6c83\u5229\u5355\u6297\uff08PD-L1 \u5355\u57df\u6297\u4f53 Fc \u878d\u5408\u86cb\u767d\uff09\u88ab\u7eb3\u5165\u62df\u4f18\u5148\u5ba1\u8bc4\uff0c\u62df\u5b9a\u9002\u5e94\u75c7\u4e3a\u5fae\u536b\u661f\u9ad8\u5ea6\u4e0d\u7a33\u5b9a(MSI-H)\u665a\u671f\u7ed3\u76f4\u80a0\u764c\u548c MSI-H \u665a\u671f\u80c3\u764c\u53ca\u5176 DNA \u9519\u914d\u4fee\u590d\u529f\u80fd\u7f3a\u9677(dMMR)\u665a\u671f\u5b9e\u4f53\u7624\u3002<\/div>\n
\u00a0<\/div>\n
04\u00a0\u79d1\u7814<\/div>\n
\u2756\u00a0\u53e4DNA\u5206\u6790\u63ed\u793a\u7ef4\u4eac\u65f6\u4ee3\u7684\u4eba\u7c7b\u8fc1\u5f99<\/div>\n
\u54e5\u672c\u54c8\u6839\u5927\u5b66\u5730\u7403\u9057\u4f20\u5b66\u7814\u7a76\u4e2d\u5fc3\u4eba\u5458\u5bf9\u9752\u94dc\u65f6\u4ee3\u81f3\u8fd1\u73b0\u4ee3\u65f6\u671f\u57cb\u846c\u5728\u6b27\u6d32\u548c\u683c\u9675\u5170\u53e4\u7ef4\u4eac\u516c\u5893\u7684400\u591a\u4eba\u7684DNA\u8fdb\u884c\u4e86\u6d4b\u5e8f\uff0c\u5c06\u57fa\u56e0\u7ec4\u4e0e\u5176\u4ed61100\u591a\u79cd\u53e4\u4eba\u7684\u5e8f\u5217\u8fdb\u884c\u6bd4\u8f83\uff0c\u53d1\u73b0\u8bb8\u591a\u5317\u6b27\u6d77\u76d7\u5728\u65af\u582a\u7684\u7eb3\u7ef4\u4e9a\u534a\u5c9b\u5185\u5916\u90fd\u5177\u6709\u5f88\u9ad8\u7684\u975e\u65af\u582a\u7684\u7eb3\u7ef4\u4e9a\u8840\u7edf\uff0c\u8fd9\u8868\u660e\u6574\u4e2a\u6b27\u6d32\u90fd\u5b58\u5728\u6301\u7eed\u7684\u57fa\u56e0\u6d41\u52a8\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41586-020-2688-8<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u6211\u56fd\u63ed\u793a\u65b0\u51a0\u75c5\u6bd2\u5168\u75c5\u6bd2\u7cbe\u7ec6\u7ed3\u6784<\/div>\n
9\u670816\u65e5\uff0c\u674e\u5170\u5a1f\u9662\u58eb\u8bfe\u9898\u7ec4\u8054\u5408\u6e05\u534e\u5927\u5b66\u8bfe\u9898\u7ec4\uff0c\u5728\u56fd\u9645\u4e0a\u9996\u6b21\u89e3\u6790\u4e86\u771f\u5b9e\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u5168\u75c5\u6bd2\u4e09\u7ef4\u7cbe\u7ec6\u7ed3\u6784\uff0c\u8fbe\u5230\u4e86\u524d\u6240\u672a\u6709\u7684\u5206\u8fa8\u7387\uff0c\u5e76\u539f\u4f4d\u63ed\u793a\u4e86\u523a\u7a81\u86cb\u767d\u7684\u5929\u7136\u6784\u8c61\u53ca\u5176\u5206\u5e03\u7279\u5f81\uff0c\u4ee5\u53ca\u6838\u7cd6\u6838\u86cb\u767d\u590d\u5408\u7269\u5728\u75c5\u6bd2\u4f53\u5185\u7684\u7ed3\u6784\u53ca\u5176\u5206\u5b50\u7ec4\u88c5\u8fc7\u7a0b\uff0c\u5bf9\u6df1\u5165\u4e86\u89e3\u65b0\u51a0\u75c5\u6bd2\u7684\u751f\u7269\u7279\u6027\u3001\u75ab\u82d7\u8bbe\u8ba1\u3001\u6297\u75c5\u6bd2\u836f\u7269\u7814\u53d1\u7b49\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>DOI\uff1a10.1016 \/ j.cell.2020.09.018<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u9996\u6b21\u63cf\u7ed8<\/div>\n
\u6708\u7ecf\u5468\u671f\u4e2d\u4eba\u7c7b\u5b50\u5bab\u5185\u819c\u7684\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u56fe\u8c31<\/div>\n
\u8fd1\u65e5\uff0c\u7f8e\u56fd\u65af\u5766\u798f\u5927\u5b66\u7684\u7814\u7a76\u4eba\u5458\u901a\u8fc7\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u5206\u6790\uff0c\u5728\u6574\u4e2a\u6708\u7ecf\u5468\u671f\u7684\u5355\u7ec6\u80de\u5206\u8fa8\u7387\u4e0b\u8868\u5f81\u4e86\u4eba\u7c7b\u5b50\u5bab\u5185\u819c\u7684\u8f6c\u5f55\u7ec4\u8f6c\u5316\uff0c\u4ece\u800c\u5728\u591a\u4e2a\u7ef4\u5ea6\u4e0a\u89e3\u51b3\u4e86\u7ec6\u80de\u5f02\u8d28\u6027\u3002\u5728\u5206\u5b50\u548c\u5b9a\u91cf\u6c34\u5e73\u5c06\u6708\u7ecf\u5468\u671f\u5206\u4e3a\u56db\u4e2a\u4e3b\u8981\u9636\u6bb5\uff0c\u5e76\u4e14\u80fd\u591f\u66f4\u7cbe\u786e\u5730\u786e\u5b9a\u80da\u80ce\u201c\u7740\u5e8a\u7a97\u53e3\u201d\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41591-020-1040-1<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u9996\u6b21\u89e3\u6790\u795e\u7ecf\u6bcd\u7ec6\u80de\u7624\u5355\u7ec6\u80de\u56fe\u8c31<\/div>\n
9\u670817\u65e5\uff0c\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u513f\u79d1\u533b\u9662\u56e2\u961f\u548c\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u56e2\u961f\u5229\u7528\u5355\u7ec6\u80de\u6d4b\u5e8f\u6280\u672f\u9996\u6b21\u89e3\u6790\u4e86\u513f\u7ae5\u795e\u7ecf\u6bcd\u7ec6\u80de\u7624\u7684\u5355\u7ec6\u80de\u56fe\u8c31\uff0c\u4e3a\u4eba\u4eec\u6df1\u5165\u4e86\u89e3\u795e\u7ecf\u6bcd\u7ec6\u80de\u7624\u7684\u53d1\u75c5\u673a\u5236\u63d0\u4f9b\u4e86\u65b0\u7684\u89c6\u89d2\u3002\u76f8\u5173\u7814\u7a76\u6210\u679c\u53d1\u8868\u5728Cancer Cell\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1016\/j.ccell.2020.08.014<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u80bf\u7624\u4ea7\u751f\u7684\u8272\u6c28\u9178\u4ee3\u8c22\u9176\u6216\u662f\u65b0\u514d\u75ab\u6cbb\u7597\u9776\u70b9<\/div>\n
\u8fd1\u65e5\uff0c\u5fb7\u56fd\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\u548c\u67cf\u6797\u5065\u5eb7\u7814\u7a76\u6240\u7b49\u56e2\u961f\u627e\u5230\u4e86\u4e00\u4e2a\u764c\u75c7\u514d\u75ab\u6cbb\u7597\u7684\u65b0\u6f5c\u5728\u9776\u70b9\u2014\u2014IL4I1\u3002IL4I1\u662f\u4e00\u4e2a\u4ee3\u8c22\u9176\uff0c\u7531\u80bf\u7624\u4ea7\u751f\uff0c\u5206\u89e3\u8272\u6c28\u9178\u5f97\u5230\u7684\u4ee3\u8c22\u7269\u80fd\u591f\u6fc0\u6d3b\u82b3\u70c3\u53d7\u4f53\uff08AHR\uff09\uff0c\u4ece\u800c\u589e\u5f3a\u80bf\u7624\u7684\u4fb5\u88ad\u6027\uff0c\u8fd8\u6291\u5236\u6297\u80bf\u7624\u514d\u75ab\u3002\u56e0\u6b64\uff0cIL4I1\u6291\u5236\u53ef\u80fd\u662f\u4e00\u79cd\u65b0\u7684\u514d\u75ab\u6cbb\u7597\u9014\u5f84\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1016\/j.cell.2020.07.038<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Nature\uff1a\u5229\u7528\u57fa\u56e0\u7ec4\u5efa\u6a21\u9884\u6d4b\u764c\u75c7\u7ec6\u80de\u4f55\u65f6\u514d\u75ab\u9003\u9038<\/div>\n
9\u670814\u65e5\uff0c\u82f1\u56fd\u764c\u75c7\u7814\u7a76\u9662\u7b49\u56e2\u961f\u8054\u5408\u5f00\u53d1\u4e86\u4e00\u79cd\u6a21\u578b\uff0c\u5229\u7528\u4e86\u6765\u81ea\u764c\u75c7\u57fa\u56e0\u7ec4\u56fe\u8c31\u6570\u636e\uff08\u80a0\u764c\uff0c\u80c3\u764c\u548c\u5b50\u5bab\u5185\u819c\u764c\u7b49\uff09\uff0c\u8ba1\u7b97\u80bf\u7624\u4e2d\u65b0\u6297\u539f\u7684\u7b49\u4f4d\u57fa\u56e0\u9891\u7387\u53ca\u79ef\u7d2f\u7684\u901f\u5ea6\u3002\u8be5\u6a21\u578b\u8be5\u7ed8\u5236\u51fa\u80bf\u7624\u8fdb\u5316\u8fc7\u7a0b\u4e2d\uff0c\u764c\u7ec6\u80de\u4e0e\u514d\u75ab\u7ec6\u80de\u4e4b\u95f4\u7684\u7ade\u4e89\u8def\u7ebf\u56fe\uff0c\u80fd\u9884\u6d4b\u764c\u75c7\u7ec6\u80de\u4f55\u65f6\u53ef\u80fd\u6fc0\u6d3b\u514d\u75ab\u9003\u9038\u673a\u5236\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41588-020-0687-1<\/div>\n
\u00a0<\/div>\n
\u62d3\u5c55\u9605\u8bfb<\/div>\n
2020 CSCO \u5b66\u672f\u4f1a\u8bae\u53ca\u7cbe\u9009\u536b\u661f\u4f1a\u65e5\u7a0b<\/a>\u6211\u56fd\u57fa\u56e0\u6cbb\u7597\u4e09\u5927\u73b0\u72b6\uff0c\u53d1\u5c55\u7a7a\u95f4\u5de8\u5927<\/a>13\u5bb6\u57fa\u56e0\u4f01\u4e1aQ2\u8d22\u62a5\u5206\u6790\uff1a\u4f7f\u547d\u5927\u4e8e\u673a\u9047\u57fa\u56e0<\/a><\/div>\n
\u3010\u58f0\u660e\u3011\u4e3a\u4f20\u64ad\u79d1\u5b66\u4fe1\u606f\uff0c\u63a8\u52a8\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u5b66\u7814\u8fde\u63a5\uff0c\u6211\u4eec\u79c9\u6301\u4e2d\u7acb\u3001\u4e13\u4e1a\u3001\u8d4b\u80fd\u7684\u7406\u5ff5\u6536\u96c6\u3001\u5206\u6790\u6216\u53d1\u5e03\u4fe1\u606f\u3002\u4f46\u7531\u4e8e\u65f6\u6548\u6027\u53ca\u884c\u4e1a\u7279\u6b8a\u6027\uff0c\u6240\u520a\u767b\u5185\u5bb9\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u4e0d\u4f5c\u4e3a\u51b3\u7b56\u4f9d\u636e\uff1b\u672c\u6587\u76f8\u5173\u4fe1\u606f\u4e0d\u4ee3\u8868\u57fa\u56e0\u6167\u673a\u6784\u7684\u89c2\u70b9\uff1b\u201c\u57fa\u56e0\u6167\u201d\u520a\u767b\u7684\u539f\u521b\u5185\u5bb9\u7684\u77e5\u8bc6\u4ea7\u6743\u4e3a\u201c\u57fa\u56e0\u6167\u201d\u5546\u6807\u62e5\u6709\u8005\u53ca\u76f8\u5173\u6743\u5229\u4eba\u6240\u6709\uff1b\u6b22\u8fce\u8f6c\u8f7d\uff0c\u8f6c\u8f7d\u8bf7\u7533\u8bf7\u5e76\u6ce8\u660e\u6765\u6e90\u3002\u6b22\u8fce\u4e2a\u4eba\u53ca\u673a\u6784\u6295\u7a3f\u53ca\u5408\u4f5c\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u5173\u4e8e\u6211\u4eec\u00a0<\/div>\n
\u57fa\u56e0\u6167\u662f\u6570\u5b57\u751f\u547d\u5065\u5eb7\u9886\u57df\u521b\u65b0\u670d\u52a1\u5e73\u53f0\u3002\u56e2\u961f\u6df1\u8015\u884c\u4e1a\u5341\u4f59\u5e74\uff0c\u4ece\u884c\u7814\u54a8\u8be2\u3001\u5a92\u4f53\u8d44\u8baf\u3001\u4ea7\u4e1a\u6570\u636e\u5e93\u7b49\u65b9\u9762\u63d0\u4f9b\u4f18\u8d28\u5185\u5bb9\u670d\u52a1\u3002\u57fa\u56e0\u6167\u4f5c\u4e3a\u56fd\u53d1\u6539\u4ea7\u4e1a\u7814\u7a76\u5408\u4f5c\u5355\u4f4d\uff0c\u8054\u5408\u591a\u5bb6\u4e13\u4e1a\u673a\u6784\u53d1\u5e03\u4e86\u591a\u4efd\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u9886\u57df\u884c\u7814\u62a5\u544a\uff0c\u53c2\u4e0e\u7ec4\u7ec7\u53d1\u5e03\u4e86\u4e24\u4efd\u884c\u4e1a\u5171\u8bc6\u548c\u4e00\u9879\u56e2\u4f53\u6807\u51c6\uff0c\u81f4\u529b\u4e8e\u5efa\u8bbe\u4ea7\u4e1a\u4fe1\u606f\u5927\u6570\u636e\u5e73\u53f0\uff0c\u670d\u52a1\u751f\u547d\u79d1\u6280\u521b\u65b0\u521b\u4e1a\u3002<\/div>\n
\u2606\u00a0\u56fd\u53d1\u6539\u300a\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b\u7f16\u59d4<\/a><\/div>\n
\u2606\u00a0\u53c2\u4e0e\u7ec4\u7ec7\u53d1\u5e03\u68c0\u6d4b\u62a5\u544a\u5171\u8bc6\u3001\u6d41\u7a0b\u5171\u8bc6\u548c\u56e2\u4f53\u6807\u51c6<\/div>\n
\u2606\u00a0\u4e2d\u56fd\u9057\u4f20\u5b66\u4f1a\u751f\u7269\u4ea7\u4e1a\u4fc3\u8fdb\u59d4\u5458\u4f1a\u59d4\u5458<\/div>\n
\u2606\u00a0\u53d1\u5e03\u6570\u5341\u4efd\u57fa\u56e0\u53ca\u76f8\u5173\u884c\u7814\u62a5\u544a<\/a><\/div>\n
\u2606\u00a0\u7ec4\u7ec7\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\uff08\u7b79\uff09\u53ca\u9996\u5c4a<\/a>\u548c\u7b2c\u4e8c\u5c4a<\/a>\u4f1a\u8bae<\/a><\/div>\n
\u2606\u00a0\u53d1\u5e03\u4ea7\u4e1a\u5927\u6570\u636e\u5e73\u53f0\u4f18\u8109\u901aYourMap<\/a><\/div>\n
\u2606\u00a0\u4e3b\u529e\u6570\u5b57\u5065\u5eb7\u79c1\u8463\u4f1a<\/a>\u3001\u5927\u6e7e\u533a\u751f\u547d\u5065\u5eb7\u521b\u65b0\u8bba\u575b<\/a><\/div>\n
\u2606\u00a0\u53d7\u9080\u4e3a\u534e\u897f<\/a>\u3001Illumina<\/a>\u3001\u534e\u5927<\/a>\u3001\u4e0a\u6d77\u4ea4\u5927<\/a>\u7b49\u62a5\u544a<\/div>\n
\u2606\u00a0\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5e94\u7528\u5b66\u4f1a\u653f\u7b56\u7814\u7a76\u5e94\u7528\u5206\u4f1a\u5e38\u52a1\u59d4\u5458<\/div>\n
\u2606\u00a0\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5e94\u7528\u5b66\u4f1a\u9057\u4f20\u75c5\u5206\u4f1a\u5e38\u52a1\u59d4\u5458<\/div>\n\n
\n
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\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u5bfc\u822aGeneMail 113 \u671f<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"close","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[996],"tags":[2031,1444],"class_list":["post-9033","post","type-post","status-publish","format-standard","hentry","category-news","tag-cde","tag-1444"],"_links":{"self":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9033","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/comments?post=9033"}],"version-history":[{"count":3,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9033\/revisions"}],"predecessor-version":[{"id":13723,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/9033\/revisions\/13723"}],"wp:attachment":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/media?parent=9033"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/categories?post=9033"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/tags?post=9033"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}