{"id":8976,"date":"2020-12-07T03:29:15","date_gmt":"2020-12-06T19:29:15","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100017733&idx=1&sn=1c0a1671270c01a86e0ca61b363c3453&chksm=6b7174f25c06fde4f18829c16b49ed0584367e3f806234cae030ff1840624cf4e7361ca90fcf#rd"},"modified":"2026-04-01T16:43:45","modified_gmt":"2026-04-01T08:43:45","slug":"1015297","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2020\/12\/07\/1015297\/","title":{"rendered":"\u57fa\u56e0\u7b80\u62a5\u4e28\u7ebd\u7ea6\u5c1d\u9c9c\u4e34\u5e8a\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\uff0c\u86cb\u767d\u8d28\u7ec4\u5b66\u516c\u53f8Seer\u4e0a\u5e02"},"content":{"rendered":"
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\"RmFicvQBAkgCczz1Qv6G69jHD739wp5picIffAtHnqYOUN5Lpe2grbx4CNNX9GIODWQrhnZQyzUln6UlkYNUEfvA\"\/<\/figure><\/div>\n\n
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\u2756NMPA\u53d1\u5e03\u4f53\u5916\u8bca\u65ad\u8bd5\u5242<\/div>\n
\u5883\u5916\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u7684\u6280\u672f\u6307\u5357<\/div>\n
2020\u5e7411\u670826\u65e5\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u533b\u7597\u5668\u68b0\u6280\u672f\u5ba1\u8bc4\u4e2d\u5fc3\u53d1\u5e03\u4e86\u300a\u4f7f\u7528\u4f53\u5916\u8bca\u65ad\u8bd5\u5242\u5883\u5916\u4e34\u5e8a\u8bd5\u9a8c\u6570\u636e\u7684\u6280\u672f\u6307\u5357\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b\u3002<\/div>\n
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2020\u5e7412\u67081\u65e5\uff0c\u9999\u6e2f\u884c\u653f\u957f\u5b98\u6797\u90d1\u6708\u5a25\u8868\u793a\uff0c\u9488\u5bf9\u5c06\u672a\u6709\u76c8\u5229\u7684\u751f\u7269\u79d1\u6280\u516c\u53f8\u7eb3\u5165\u4e92\u8054\u4e92\u901a\u8303\u56f4\u6709\u8fdb\u5c55\uff0c\u5408\u8d44\u683c\u516c\u53f8\u5c06\u4e8e\u4e00\u4e2a\u6708\u540e\u53ef\u7eb3\u5165\u80a1\u7968\u6807\u7684\u8303\u56f4\uff0c\u5e76\u900f\u8fc7\u6caa\u6df1\u6e2f\u901a\u8fdb\u884c\u4ea4\u6613\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0NMPA\u6279\u51c6Illumina NextSeq 550Dx<\/div>\n
\u6d4b\u5e8f\u4eea\u7528\u4e8e\u4e34\u5e8a\u8bca\u65ad<\/div>\n
2020\u5e7412\u67081\u65e5\uff0cIIllumina\u8868\u793a\uff0c\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u5df2\u6279\u51c6\u5176NextSeq 550Dx\u6d4b\u5e8f\u4eea\u5728\u4e34\u5e8a\u4e0a\u7528\u4e8e\u4eba\u6e90\u6837\u672c\u7684\u4eba\u7c7bDNA\u68c0\u6d4b\u8bca\u65ad\u3002Illumina\u73b0\u62e5\u6709\u4e24\u4e2aNMPA\u6279\u51c6\u7684\u4e34\u5e8a\u7ea7\u6d4b\u5e8f\u4eea\uff0c\u53e6\u4e00\u6b3e\u662fMiSeq Dx\u3002<\/div>\n
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\u6280\u672f<\/div>\n
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2020\u5e7411\u670827\u65e5\uff0cScience\u671f\u520a\u53d1\u8868\u7814\u7a76\u7ed3\u679c\u79f0\uff0cBroad\u7814\u7a76\u6240\u7684\u5f20\u950b\u3001Aviv Regev\u7b49\u56e2\u961f\u57fa\u4e8eCRISPR-Cas9\u548c\u5355\u7ec6\u80deRNA\u6d4b\u5e8f\u6280\u672f\u5f00\u53d1\u4e86\u4e00\u79cd\u9ad8\u901a\u91cf\u7684\u57fa\u56e0\u68c0\u6d4b\u65b9\u6cd5\uff0c\u5373\u4f53\u5185Perturb-Seq\uff0c\u53ef\u5728\u5355\u7ec6\u80de\u5206\u8fa8\u7387\u4e0b\u7814\u7a76\u4f53\u5185\u590d\u6742\u7ec4\u7ec7\u4e2d\u591a\u57fa\u56e0\u7684\u529f\u80fd\u3002\u6b64\u6b21\u7814\u7a76\u5206\u6790\u4e8635\u4e2aASD\/ND\u98ce\u9669\u57fa\u56e0\u5bf9\u5c0f\u9f20\u5927\u8111\u53d1\u80b2\u7684\u5f71\u54cd\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>doi:10.1126\/science.aaz6063<\/div>\n
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\u2756\u00a0DNA\u8054\u5408RNA\u53ca\u86cb\u767d\u8d28\u6570\u636e<\/div>\n
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2020\u5e7411\u670826\u65e5\uff0c\u80f8\u90e8\u80bf\u7624\u5b66\u6742\u5fd7(Journal of Thoracic Oncology)\u5728\u7ebf\u53d1\u8868\u4e86\u9488\u5bf9\u975e\u5c0f\u7ec6\u80de\u80ba\u764cALK\/ROS1\/RET\u878d\u5408\u57fa\u56e0\u5206\u5b50\u75c5\u7406\u7cbe\u51c6\u68c0\u6d4b\u7684\u6587\u7ae0\u3002\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u4e34\u5e8a\u4e0a\u4ec5\u4f9d\u9760NGS\u57fa\u56e0\u6c34\u5e73\u68c0\u6d4b\u51fa\u7684\u7f55\u89c1ALK\u878d\u5408\u65ad\u70b9\u6765\u9884\u6d4b\u9776\u5411\u6cbb\u7597\u7684\u7597\u6548\u53ef\u80fd\u5e76\u4e0d\u51c6\u786e\uff0c\u8054\u5408\u5e94\u7528RNA\/\u86cb\u767d\u6c34\u5e73\u7684\u68c0\u6d4b\u53ef\u80fd\u6548\u679c\u66f4\u597d\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>doi:10.1016\/j.jtho.2020.10.156<\/div>\n
\u00a0<\/div>\n
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\u8fd1\u65e5\uff0cDeepMind\u5ba3\u5e03\uff0c\u5176\u65b0\u4e00\u4ee3AlphaFold\u4eba\u5de5\u667a\u80fd\u7cfb\u7edf\uff0c\u5728\u56fd\u9645\u86cb\u767d\u8d28\u7ed3\u6784\u9884\u6d4b\u7ade\u8d5b\uff08CASP\uff09\u4e0a\u51fb\u8d25\u4e86\u5176\u4f59\u7684\u53c2\u4f1a\u9009\u624b\uff0c\u80fd\u591f\u7cbe\u786e\u5730\u57fa\u4e8e\u6c28\u57fa\u9178\u5e8f\u5217\uff0c\u9884\u6d4b\u86cb\u767d\u8d28\u76843D\u7ed3\u6784\u3002\u5176\u51c6\u786e\u6027\u53ef\u4ee5\u4e0e\u4f7f\u7528\u51b7\u51bb\u7535\u5b50\u663e\u5fae\u955c\uff08CryoEM\uff09\u3001\u6838\u78c1\u5171\u632f\u6216 X \u5c04\u7ebf\u6676\u4f53\u5b66\u7b49\u5b9e\u9a8c\u6280\u672f\u89e3\u6790\u76843D\u7ed3\u6784\u76f8\u5ab2\u7f8e\u3002<\/div>\n
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\u2756\u00a0\u6700\u5927\u89c4\u6a21\u7684\u83b2\u57fa\u56e0\u7ec4\u91cd\u6d4b\u5e8f\u7814\u7a76\u53d1\u5e03<\/div>\n
\u8fd1\u65e5\uff0c\u6b66\u6c49\u5e02\u519c\u4e1a\u79d1\u5b66\u9662\u852c\u83dc\u7814\u7a76\u6240\u56e2\u961f\u8054\u5408\u534e\u5927\u57fa\u56e0\u56e2\u961f\u5728The Plant Journal\u00a0\u53d1\u8868\u4e86\u7814\u7a76\u6210\u679c\u3002\u8be5\u7814\u7a76\u5229\u7528\u77ed\u8bfb\u957f\u6d4b\u5e8f\u6280\u672f\u5bf9296\u4efd\u83b2\u79cd\u8d28\u8d44\u6e90\u8fdb\u884c\u4e86\u91cd\u6d4b\u5e8f\uff0c\u6db5\u76d6\u4e86\u6765\u81ea\u5e7f\u6cdb\u5730\u7406\u5206\u5e03\u7684\u4e0d\u540c\u79cd\u3001\u751f\u6001\u578b\u53ca\u683d\u57f9\u83b2\u7c7b\u578b\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>doi\uff1a10.1111\/tpj.15029<\/div>\n
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\u5f53\u5730\u65f6\u95f412\u67083\u65e5\uff0cIllumina\u3001\u5a01\u5c14\u5eb7\u5948\u5c14\u533b\u5b66\u4e2d\u5fc3\u3001\u7ebd\u7ea6\u957f\u8001\u4f1a\u533b\u9662\u548c\u7ebd\u7ea6\u57fa\u56e0\u7ec4\u4e2d\u5fc3\u5468\u56db\u5ba3\u5e03\u4e86\u4e00\u9879\u5408\u4f5c\u8ba1\u5212\uff0c\u4e3a\u6570\u5343\u77e5\u60c5\u540c\u610f\u7684\u60a3\u8005\u63d0\u4f9b\u4e34\u5e8a\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\uff08WGS\uff09\uff0c\u4ee5\u8bc6\u522b\u9057\u4f20\u75be\u75c5\u9a71\u52a8\u56e0\u7d20\u548c\u6f5c\u5728\u7597\u6cd5\u3002\u7814\u7a76\u4eba\u5458\u5c06\u5728\u4e00\u5bb6\u96b6\u5c5e\u4e8e\u7f8e\u56fd\u4e3b\u8981\u90fd\u5e02\u533b\u7597\u7cfb\u7edf\u7684\u4e34\u5e8a\u79d1\u7814\u4e2d\u5fc3\u5185\u5b9e\u65bd\u5e76\u8bc4\u4f30WGS\u7684\u53ef\u884c\u6027\u3002<\/div>\n
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11\u670828\u65e5\u5e7f\u5dde\uff0c\u7531\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5e94\u7528\u5b66\u4f1a\u548c\u5e7f\u4e1c\u7701\u5987\u5e7c\u4fdd\u5065\u9662\u8054\u5408\u534e\u5927\u57fa\u56e0\u7b49\u884c\u4e1a\u5185\u76f8\u5173\u5355\u4f4d\u5171\u540c\u8d77\u8349\u7684\u300a\u57fa\u4e8e\u5b55\u5987\u5916\u5468\u8840\u6d46\u6e38\u79bbDNA\u9ad8\u901a\u91cf\u6d4b\u5e8f\u65e0\u521b\u4ea7\u524d\u7b5b\u67e5\u80ce\u513f\u57fa\u56e0\u7ec4\u75c5\u6280\u672f\u6807\u51c6\u300b\uff0c\u5728\u201cPMC2020\u7cbe\u51c6\u533b\u5b66\u5927\u4f1a\u201d\u4e0a\u6b63\u5f0f\u53d1\u5e03\u3002<\/div>\n
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\u53c2\u8003\u4fe1\u606f>>http:\/\/nmdc.cn<\/div>\n
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2020\u5e7411 \u6708 27 \u65e5\uff0c\u5408\u751f\u57fa\u56e0\u5ba3\u5e03\u5176\u57fa\u4e8e\u56fd\u5185\u539f\u521b\u7684\u5408\u6210\u751f\u7269\u6280\u672f\u5f00\u53d1\u7684\u9996\u6b3e\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1 SynOV1.1 \u83b7\u5f97\u7f8e\u56fd FDA \u4e34\u5e8a\u8bd5\u9a8c\u8bb8\u53ef\uff0c\u7528\u4e8e\u6cbb\u7597\u5305\u62ec\u4e2d\u665a\u671f\u809d\u764c\u5728\u5185\u7684\u7532\u80ce\u86cb\u767d\uff08AFP\uff09\u9633\u6027\u5b9e\u4f53\u7624\uff0c\u5e76\u8ba1\u5212\u8fd1\u671f\u5728\u7f8e\u56fd\u7eaa\u5ff5\u65af\u9686\u30fb\u51ef\u7279\u7433\u764c\u75c7\u4e2d\u5fc3\u5f00\u5c55 I\/IIa \u671f\u4e34\u5e8a\u7814\u7a76\u3002<\/div>\n
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2020\u5e7411\u670830\u65e5\uff0c\u7531\u836f\u660e\u5965\u6d4b\u5f00\u53d1\u7684\u201c\u4e19\u620a\u9178\u6d4b\u5b9a\u8bd5\u5242\u76d2\uff08\u6db2\u76f8\u8272\u8c31-\u4e32\u8054\u8d28\u8c31\u6cd5\uff09\u201d\u83b7\u6279\u4e8c\u7c7b\u533b\u7597\u5668\u68b0\u6ce8\u518c\u8bc1\u3002\u8be5\u4ea7\u54c1\u7cfb\u4e2d\u56fd\u9996\u4e2a\u83b7\u6279\u7684\u6db2\u76f8\u8272\u8c31-\u4e32\u8054\u8d28\u8c31\u6cd5\uff08LC-MS\/MS\uff09\u4e19\u620a\u9178\u6d4b\u5b9a\u8bd5\u5242\u76d2\uff0c\u53ef\u4e3a\u7cbe\u795e\u79d1\u533b\u751f\u7cbe\u51c6\u7528\u836f\u63d0\u4f9b\u53ef\u9760\u53c2\u8003\u3002<\/div>\n
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\u2756\u00a0\u5fae\u751f\u6001\u7597\u6cd5\u65b0\u836f MET-3\u00a0<\/div>\n
\u83b7FDA \u8bb8\u53ef\u5f00\u5c55\u4e34\u5e8a II \u671f\u8bd5\u9a8c<\/div>\n
2020\u5e7411\u670830\u65e5\uff0c\u676d\u5dde\u5955\u666f\u751f\u7269\u5ba3\u5e03\uff0c\u5176\u4e0e\u5408\u4f5c\u4f19\u4f34 Nubiyota Inc \u5171\u540c\u5f00\u53d1\u7684\u80a0\u9053\u5fae\u751f\u6001\u7597\u6cd5\u65b0\u836f MET-3\uff08Multi-strain Ecosystem Therapeutics\uff09 \u5df2\u83b7\u5f97FDA\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u8bb8\u53ef\u542f\u52a8\u7f8e\u56fd\u4e34\u5e8a II \u671f\u7814\u7a76\uff0c\u8bc4\u4f30\u9488\u5bf9\u9ad8\u7518\u6cb9\u4e09\u916f\u8840\u75c7\u548c\u80f0\u5c9b\u7d20\u62b5\u6297\u7684\u6709\u6548\u6027\u4e0e\u5b89\u5168\u6027\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u5357\u79d1\u5927\u751f\u547d\u79d1\u5b66\u5b66\u9662\u6210\u7acb<\/div>\n
2020\u5e7412\u67084\u65e5\uff0c\u5357\u65b9\u79d1\u6280\u5927\u5b66\u751f\u547d\u79d1\u5b66\u5b66\u9662\u4e3e\u884c\u63ed\u724c\u6210\u7acb\u4eea\u5f0f\u3002\u8be5\u5b66\u9662\u9996\u4efb\u9662\u957f\u7531\u795e\u7ecf\u751f\u7269\u5b66\u5bb6\u3001\u4e2d\u56fd\u79d1\u5b66\u9662\u9662\u58eb\u3001\u9999\u6e2f\u79d1\u5b66\u9662\u521b\u9662\u9662\u58eb\u5f20\u660e\u6770\u62c5\u4efb\u3002\u63ed\u724c\u4eea\u5f0f\u753113\u4f4d\u9662\u58eb\u53ca\u767e\u4f4d\u4e13\u5bb6\u7b49\u5609\u5bbe\u51fa\u5e2d\u89c1\u8bc1\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4f1a\u8bae\u63a8\u8350\uff1a<\/div>\n
2020\u4e2d\u56fd\u80bf\u7624\u6807\u5fd7\u7269\u5b66\u672f\u5927\u4f1a<\/div>\n
\uff0812.11-13\uff0c\u5e7f\u5dde\uff09<\/div>\n
2020\u5e7412\u670811\u65e5-13\u65e5\uff0c\u7531\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u80bf\u7624\u6807\u5fd7\u4e13\u4e1a\u59d4\u5458\u4f1a\u4e3b\u529e\u76842020\u5e74\u4e2d\u56fd\u80bf\u7624\u6807\u5fd7\u7269\u5b66\u672f\u5927\u4f1a\u66a8\u7b2c\u5341\u56db\u5c4a\u80bf\u7624\u6807\u5fd7\u7269\u9752\u5e74\u79d1\u5b66\u5bb6\u8bba\u575b\u5c06\u4e8e\u5e7f\u5dde\uff08\u4e3b\u4f1a\u573a\uff09\u53ec\u5f00\u3002\u5c4a\u65f6\u5c06\u4e3e\u884c40+\u4e3b\u9898\u8bba\u575b\u53ca\u4e13\u9898\u6d3b\u52a8\uff0c300+\u5b66\u672f\u62a5\u544a\uff0c\u5176\u4e2d\u5305\u62ec\u201c\u80bf\u7624\u6807\u5fd7\u7269\u9886\u57df\u5e74\u5ea6\u5341\u5927\u8fdb\u5c55\u8bc4\u9009\u201d\u7b49\u6d3b\u52a8\u3002<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a<\/div>\n
\u2756\u00a0\u86cb\u767d\u8d28\u7ec4\u5b66\u516c\u53f8Seer\u4e0a\u5e02<\/div>\n
\u52df\u8d441.75\u4ebf\u7f8e\u5143<\/div>\n
\u5f53\u5730\u65f6\u95f42020\u5e7412\u67083\u65e5\u665a\u95f4\uff0c\u86cb\u767d\u8d28\u7ec4\u5b66\u516c\u53f8Seer\uff08NASDQ\uff1aSEER\uff09\u5c06\u51769,210,527\u80a1\u666e\u901a\u80a1\u7684\u9996\u6b21\u516c\u5f00\u53d1\u884c\u5b9a\u4ef7\u4e3a\u6bcf\u80a119\u7f8e\u5143\uff0c\u9884\u671f\u603b\u6536\u76ca\u4e3a1.75\u4ebf\u7f8e\u5143\u3002Seer\u6b64\u6b21\u4e0a\u5e02\u52df\u8d44\u7684\u6838\u5fc3\u76ee\u7684\u662f\u7814\u53d1\u548c\u5546\u4e1a\u5316Proteograph\u7cfb\u7edf\u2014\u2014\u57fa\u4e8e\u7eb3\u7c73\u9897\u7c92\u7684\u86cb\u767d\u8d28\u86cb\u767d\u8d28\u5bcc\u96c6\u65b9\u6cd5\u6765\u5b9e\u73b0\u66f4\u7ec6\u9897\u7c92\u5ea6\u7684\u86cb\u767d\u8d28\u7ec4\u5b66\u7814\u7a76\u3002\u8be5\u7cfb\u7edf\u8ba1\u5212\u57282021\u5e74\u5f00\u59cb\u51fa\u552e\u5e76\u4e8e2022\u5e74\u5e7f\u6cdb\u4f7f\u7528\u3002\u4eca\u5e749\u6708\uff0cSeer\u4ece\u533b\u7597\u5065\u5eb7\u516c\u53f8PrognomIQ\u5b75\u5316\u51fa\u6765\uff0c\u9996\u8f6e\u878d\u8d44\u83b7\u5f975500\u4e07\u7f8e\u5143\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u836f\u660e\u5eb7\u5fb7\u5ba3\u5e03\u4e0eViGeneron\u8fbe\u6210<\/div>\n
\u65b0\u4e00\u4ee3\u773c\u79d1\u57fa\u56e0\u7597\u6cd5\u4ea7\u54c1\u751f\u4ea7\u5408\u4f5c<\/div>\n
2020\u5e7412\u67081\u65e5\uff0c\u836f\u660e\u5eb7\u5fb7\u65d7\u4e0b\u4e13\u6ce8\u4e8e\u7ec6\u80de\u548c\u57fa\u56e0\u7597\u6cd5\u7684CTDMO\u836f\u660e\u751f\u57fa\u5ba3\u5e03\u4e0e\u57fa\u56e0\u6cbb\u7597\u516c\u53f8ViGeneron\u8fbe\u6210\u6218\u7565\u5408\u4f5c\uff0c\u4e3aViGeneron\u65b0\u4e00\u4ee3\u773c\u79d1\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1VG901\u63d0\u4f9b\u4e34\u5e8a\u5f00\u53d1\u9636\u6bb5\u7684\u751f\u4ea7\u670d\u52a1\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u62dc\u8033\u5efa\u7acb\u7ec6\u80de\u548c\u57fa\u56e0\u6cbb\u7597\u5e73\u53f0<\/div>\n
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\u00a0<\/div>\n
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2020\u5e7412\u67081\u65e5\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u5317\u4eac\u57fa\u56e0\u7ec4\u7814\u7a76\u6240\uff08\u56fd\u5bb6\u751f\u7269\u4fe1\u606f\u4e2d\u5fc3\uff09\u4e0e\u534e\u4e3a\u8f6f\u4ef6\u6280\u672f\u6709\u9650\u516c\u53f8\u5728\u6df1\u5733\u534e\u4e3a\u5742\u7530\u57fa\u5730\u7b7e\u7f72\u5408\u4f5c\u534f\u8bae\u3002\u6839\u636e\u534f\u8bae\uff0c\u5317\u4eac\u57fa\u56e0\u7ec4\u6240\u4e0e\u534e\u4e3a\u5c06\u5728\u6570\u636e\u4e2d\u5fc3\u57fa\u7840\u5e73\u53f0\u5efa\u8bbe\u3001\u79d1\u7814\u521b\u65b0\u3001\u4eba\u624d\u57f9\u517b\u7b49\u65b9\u9762\u5c55\u5f00\u5408\u4f5c\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0GRAIL\u4e0e\u82f1\u56fd\u653f\u5e9c\u5408\u4f5c<\/div>\n
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\u00a0<\/div>\n
\u6587\u7ae0\/\u57fa\u56e0\u6167<\/div>\n
\u7f16\u8f91\/Shawne<\/div>\n
\u5ba1\u6838\/Barney<\/div>\n
\u62d3\u5c55\u9605\u8bfb<\/div>\n
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\u7b03\u884c\u81f4\u8fdc\uff0c2021\u57fa\u56e0\u884c\u4e1a\u84dd\u76ae\u4e66\u542f\u52a8\u5408\u4f5c<\/a><\/div>\n\n
\n
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\u00a0<\/div>\n
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\n
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