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\u2756\u00a0\u5b89\u5409\u5eb7\u5c14\u5b8c\u62101\u4ebf\u5143B\u8f6e\u878d\u8d44<\/div>\n
12\u670825\u65e5\uff0c\u5b89\u5409\u5eb7\u5c14\uff08\u6df1\u5733\uff09\u79d1\u6280\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u5b89\u5409\u5eb7\u5c14\u201d\uff09\u5ba3\u5e03\u5b8c\u6210 1\u4ebf\u5143B\u8f6e\u878d\u8d44\u3002\u672c\u8f6e\u878d\u8d44\u7531\u535a\u884c\u8d44\u672c\u9886\u6295\uff0c\u6fb3\u94f6\u8d44\u672c\u3001\u6a2a\u7434\u91d1\u6295\u8ddf\u6295\u3002\u636e\u6089\uff0c\u672c\u8f6e\u878d\u8d44\u5c06\u7528\u4e8e\u52a0\u5f3a\u5b89\u5409\u5eb7\u5c14\u57fa\u56e0\u667a\u80fdAEGIS\u2122\u7cfb\u7edf\u7684\u7814\u53d1\u521b\u65b0\uff0c\u5e76\u91cd\u70b9\u63a8\u8fdb\u57fa\u56e0\u7ec4\u75be\u75c5IVD\u533b\u7597\u5668\u68b0\u4ea7\u54c1\u6ce8\u518c\u7533\u62a5\u3002<\/div>\n
\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u5b89\u5409\u5eb7\u5c14\u4e8e2019\u5e74\u63a8\u51faCompleteCare\u2122\u5168\u57fa\u56e0\u7ec4\u4e34\u5e8a\u7efc\u5408\u89e3\u51b3\u65b9\u6848\uff0c\u5728\u5168\u9762\u66ff\u4ee3\u5168\u5916\u663e\u5b50\u68c0\u6d4b\u3001\u7ebf\u7c92\u4f53\u68c0\u6d4b\u3001\u67d3\u8272\u4f53\u5fae\u9635\u5217\u5206\u6790\u7b49\u4f20\u7edf\u4e34\u5e8a\u9057\u4f20\u5206\u5b50\u68c0\u6d4b\u6280\u672f\u57fa\u7840\u4e0a\uff0c\u7cfb\u7edf\u6027\u5730\u586b\u8865\u4e86\u957f\u671f\u4ee5\u6765\u4f20\u7edf\u65b9\u6848\u5728\u7ed3\u6784\u6027\u53d8\u5f02\u3001\u62f7\u8d1d\u6570\u53d8\u5f02\u3001\u6df1\u5ea6\u5185\u542b\u5b50\u3001\u5047\u57fa\u56e0\u7b49\u65b9\u9762\u7684\u68c0\u6d4b\u7a7a\u767d\u3002\u4e00\u5e74\u4ee5\u6765\u56de\u987e\u6027\u6570\u636e\u663e\u793aCompleteCare\u2122\u7efc\u5408\u8bca\u65ad\u7387\u4e3a46%\uff0c\u663e\u8457\u9ad8\u4e8e\u4f20\u7edf\u65b9\u6848\u3002\u56fd\u5185\u5916\u884c\u4e1a\u5171\u8bc6\u5728\u4e0d\u4e45\u7684\u5c06\u6765\uff0c\u5168\u57fa\u56e0\u7ec4\u5fc5\u5c06\u6210\u4e3a\u57fa\u56e0\u7ec4\u75be\u75c5\u4e34\u5e8a\u5206\u5b50\u8bca\u65ad\u9996\u8981\u9009\u62e9\uff08\u6d4b\u5e8f\u4e2d\u56fd\uff09\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u91d1\u573b\u777f\u751f\u7269\u5b8c\u62101\u4ebf\u5143B\u8f6e\u878d\u8d44<\/div>\n
12\u670825\u65e5\uff0c\u5e7f\u5dde\u4f73\u9274\u751f\u7269\u6280\u672f\u6709\u9650\u516c\u53f8\u5ba3\u5e03\u6210\u529f\u5b8c\u62101\u4ebf\u5143\u4eba\u6c11\u5e01B\u8f6e\u878d\u8d44\u3002\u5e7f\u5dde\u5e02\u91d1\u573b\u777f\u751f\u7269\u79d1\u6280\u6709\u9650\u8d23\u4efb\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0\u4e3a\uff1a\u91d1\u573b\u777f\uff09\u662f\u4f73\u9274\u751f\u7269\u7684IVD\u4e1a\u52a1\u8fd0\u8425\u4e3b\u4f53\u3002\u672c\u8f6e\u878d\u8d44\u7531\u6613\u65b9\u8fbe\u8d44\u672c\u9886\u6295\uff0c\u8001\u80a1\u4e1c\u541b\u8054\u8d44\u672c\u7ee7\u7eed\u8ffd\u52a0\u6295\u8d44\u3002\u672c\u8f6e\u878d\u8d44\u5c06\u7528\u4e8e\u8fdb\u4e00\u6b65\u52a0\u5f3a\u91d1\u573b\u777f\u751f\u7269\u5728\u80bf\u7624\u4f34\u968f\u8bca\u65ad\u3001\u75c5\u539f\u5fae\u751f\u7269\u3001\u9057\u4f20\u6027\u75be\u75c5\u7b49\u76f8\u5173\u7684\u591a\u6b3e\u57fa\u56e0\u68c0\u6d4b\u4ea7\u54c1\u7684\u7814\u53d1\u521b\u65b0\u548c\u5f15\u8fdb\u8f6c\u5316\uff1b\u52a0\u5feb\u5176IVD\u4ea7\u54c1\u7684\u6ce8\u518c\u7533\u62a5\uff1b\u63a8\u52a8\u91d1\u573b\u777f\u5e02\u573a\u6e20\u9053\u7684\u90e8\u7f72\u548c\u62d3\u5c55\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u5361\u5c24\u8fea\u5b8c\u6210\u8fd16\u4ebf\u5143D\u8f6e\u878d\u8d44<\/div>\n
12\u670823\u65e5\uff0c\u5361\u5c24\u8fea\u5ba3\u5e03\u6b63\u5f0f\u5b8c\u6210\u8fd16\u4ebf\u5143D\u8f6e\u878d\u8d44\u3002\u672c\u8f6e\u878d\u8d44\u7531\u9ad8\u74f4\u521b\u6295\u9886\u6295\uff0c\u91d1\u9616\u8d44\u672c\u6218\u7565\u6295\u8d44\uff0c\u60e0\u8fdc\u8d44\u672c\u548c\u5cf0\u745e\u8d44\u672c\u8ddf\u6295\u3002\u672c\u8f6e\u878d\u8d44\u5c06\u7528\u4e8ePOCT\u5206\u5b50\u8bca\u65ad\u76f8\u5173\u521b\u65b0\u4ea7\u54c1\u7684\u7814\u53d1\u3001\u4e34\u5e8a\u7814\u7a76\u53ca\u5e02\u573a\u8f6c\u5316\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Vertex\u4e0eSkyhawk\u5408\u4f5c\u5f00\u53d1<\/div>\n
RNA\u526a\u63a5\u8c03\u8282\u5c0f\u5206\u5b50\u65b0\u836f\uff0c\u91d1\u989d\u8d8522\u4ebf\u7f8e\u5143<\/div>\n
12\u670822\u65e5\uff0cSkyhawk Therapeutics\u548cVertex\u5ba3\u5e03\u4e00\u9879\u6218\u7565\u7814\u7a76\u5408\u4f5c\u548c\u8bb8\u53ef\u534f\u8bae\uff0c\u65e8\u5728\u53d1\u73b0\u548c\u5f00\u53d1\u53ef\u8c03\u8282RNA\u526a\u63a5\u7684\u65b0\u578b\u5c0f\u5206\u5b50\u4ee5\u6cbb\u7597\u4e25\u91cd\u75be\u75c5\u3002<\/div>\n
\u6839\u636e\u534f\u8bae\uff0cVertex\u5c06\u5411Skyhawk\u652f\u4ed84000\u4e07\u7f8e\u5143\u7684\u9884\u4ed8\u6b3e\uff0c\u83b7\u5f97\u5168\u7403\u72ec\u5bb6\u8bb8\u53ef\u6765\u9488\u5bf9\u8ba1\u5212\u9776\u6807\u53d1\u73b0\u548c\u5f00\u53d1\u7684\u5019\u9009\u4ea7\u54c1\u3002\u5728Vertex\u8d1f\u8d23\u8fdb\u4e00\u6b65\u7684\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u540e\uff0cSkyhawk\u8fd8\u6709\u8d44\u683c\u83b7\u5f97\u9ad8\u8fbe22\u4ebf\u7f8e\u5143\u7684\u6f5c\u5728\u91cc\u7a0b\u7891\u4ed8\u6b3e\u4ee5\u53ca\u672a\u6765\u9500\u552e\u7684\u6f5c\u5728\u7279\u8bb8\u6743\u4f7f\u7528\u8d39\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u81fb\u548c\u79d1\u6280\u4e0e\u9ad8\u535a\u533b\u7597\u96c6\u56e2\u8fbe\u6210\u6218\u7565\u5408\u4f5c<\/div>\n
12\u670822\u65e5\uff0c\u65e0\u9521\u81fb\u548c\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\u4e0e\u9ad8\u535a\u533b\u7597\u96c6\u56e2\u5ba3\u5e03\u8fbe\u6210\u6218\u7565\u5408\u4f5c\uff0c\u5728\u4ea7\u54c1\u5f00\u53d1\u3001\u4e1a\u52a1\u62d3\u5c55\u7b49\u591a\u65b9\u9762\u5f00\u5c55\u5408\u4f5c\uff0c\u5b9e\u73b0\u8d44\u6e90\u5171\u4eab\u3001\u4e13\u79d1\u9886\u57df\u4f18\u52bf\u4e92\u8865\u52a9\u529b\u8840\u6db2\u80bf\u7624\u7cbe\u51c6\u8bca\u7597\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4e2d\u79d1\u9662\u533b\u5b66\u6240\u4e0e\u534e\u5927\u96c6\u56e2\u7b7e\u7f72\u6218\u7565\u5408\u4f5c\u534f\u8bae<\/div>\n
12\u670825\u65e5\u4e0a\u5348\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u57fa\u7840\u533b\u5b66\u4e0e\u80bf\u7624\u7814\u7a76\u6240\uff08\u4ee5\u4e0b\u7b80\u79f0\u4e2d\u79d1\u9662\u533b\u5b66\u6240\uff09\u4e0e\u534e\u5927\u96c6\u56e2\u6218\u7565\u5408\u4f5c\u5ea7\u8c08\u4f1a\u5728\u676d\u5dde\u53ec\u5f00\uff0c\u53cc\u65b9\u5728\u5206\u5b50\u533b\u5b66\u3001\u6838\u9178\u9002\u4f53\u3001\u9ad8\u901a\u91cf\u6d4b\u5e8f\u3001\u65f6\u7a7a\u7ec4\u5b66\u3001\u764c\u75c7\u65e9\u7b5b\u4e0e\u9884\u6d4b\u3001\u7cbe\u51c6\u8bca\u65ad\u7b49\u524d\u6cbf\u7814\u7a76\u9886\u57df\u8fdb\u884c\u4e86\u6df1\u5165\u63a2\u8ba8\u3002<\/div>\n
\u6280\u672f<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u6211\u56fd\u9996\u4e2a\u5352\u4e2d\u4e07\u4eba\u5168\u57fa\u56e0\u7ec4\u56fe\u8c31\u53d1\u5e03<\/div>\n
12\u670818\u65e5\uff0c\u9996\u90fd\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u5317\u4eac\u5929\u575b\u533b\u9662\u738b\u62e5\u519b\u6559\u6388\u56e2\u961f\u5728Stroke & Vascular Neurology\u53d1\u8868\u7814\u7a76\u6700\u65b0\u7814\u7a76\u6210\u679c\uff0c\u4f7f\u7528BGISEQ-500\u7684\u9ad8\u901a\u91cf\u6d4b\u5e8f\u6280\u672f\u5bf9\u4e2d\u56fd\u56fd\u5bb6\u5352\u4e2d\u767b\u8bb0-III\u7684\u4e07\u4f59\u4f8b\u5352\u4e2d\u60a3\u8005\u6837\u672c\u8fdb\u884c\u5168\u57fa\u56e0\u7ec4\u6df1\u5ea6\u6d4b\u5e8f\uff0c\u7ed8\u5236\u4e86\u4e2d\u56fd\u5352\u4e2d\u4eba\u7fa4\u57fa\u56e0\u56fe\u8c31\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>Si Cheng et al., Whole genome sequencing of 10K patients with acute ischaemic stroke or transient ischaemic attack: design, methods and baseline patient characteristics, Stroke & Vascular Neurology, 2020<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u654f\u611f\u602797.1%\uff0c\u7279\u5f02\u602799.3%<\/div>\n
\u5362\u715c\u660e\u9662\u58eb\u7684\u9f3b\u54bd\u764c\u6db2\u4f53\u6d3b\u68c0\u65e9\u7b5b\u6280\u672f\u6700\u65b0\u6210\u679c<\/div>\n
12\u670819\u65e5\uff0c\u9999\u6e2f\u4e2d\u6587\u5927\u5b66\u674e\u5609\u8bda\u5065\u5eb7\u79d1\u5b66\u7814\u7a76\u6240\u6240\u957f\u5362\u715c\u660e\u9662\u58eb\u57282020\u91d1\u57df\u533b\u5b66\u5b66\u672f\u59d4\u5458\u4f1a\u4e13\u9898\u7814\u8ba8\u4f1a\u53d1\u8868\u6f14\u8bb2\uff0c\u5206\u4eab\u4e86\u8840\u6db2\u6e38\u79bbDNA\uff08EB\u75c5\u6bd2DNA\uff09\u5728\u65e0\u521b\u4ea7\u524d\u53ca\u9f3b\u54bd\u764c\u65e9\u671f\u7b5b\u67e5\u7684\u5e94\u7528\uff0c2000\u4eba\u6837\u672c\u7684\u7ed3\u679c\u8868\u660e\u9633\u6027\u9884\u6d4b\u503c\u4e3a9.5%\uff0c\u654f\u611f\u602797.1%\uff0c\u7279\u5f02\u602799.3%\u3002<\/div>\n
\u00a0<\/div>\n
\u2756 Cell\uff1a\u6a0a\u5609\u56e2\u961f\u57fa\u4e8e\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6d4b\u5e8f<\/div>\n
\u63ed\u793a\u65e9\u671f\u590d\u53d1\u6027\u809d\u764c\u7684\u80bf\u7624\u514d\u75ab\u5fae\u73af\u5883<\/div>\n
12\u670823\u65e5\uff0c\u590d\u65e6\u5927\u5b66\u4e2d\u5c71\u533b\u9662\u7684\u6a0a\u5609\u9662\u58eb\u56e2\u961f\u4e0e\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u7684\u7814\u7a76\u56e2\u961f\u5408\u4f5c\u5728Cell\u4e0a\u5728\u7ebf\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u5bf9\u6765\u81ea18\u4e2a\u539f\u53d1\u6027\u6216\u65e9\u671f\u590d\u53d1\u6027HCC\u60a3\u8005\u768416,498\u4e2a\u7ec6\u80de\u8fdb\u884c\u5168\u957f\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\uff0c\u4ece\u5355\u7ec6\u80de\u6c34\u5e73\u4e0a\u9996\u6b21\u6df1\u5ea6\u5168\u9762\u5730\u5256\u6790\u4e86\u65e9\u671f\u590d\u53d1\u6027\u809d\u764c\u7684\u514d\u75ab\u7279\u5f81\u548c\u80bf\u7624\u514d\u75ab\u9003\u9038\u673a\u5236\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>Yunfan Sun et al., Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma, Cell, 2020<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u65af\u5766\u798f\u56e2\u961f\u57fa\u4e8ectDNA\u8131\u843d\u91cf<\/div>\n
\u9884\u6d4bNSCLC\u7684\u80bf\u7624\u5927\u5c0f<\/div>\n
12\u670811\u65e5\uff0c\u65af\u5766\u798f\u5927\u5b66\u56e2\u961f\u5728Science Advances\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u901a\u8fc7\u6570\u5b66\u5efa\u6a21\uff0c\u6839\u636e\u60a3\u8005\u8840\u6db2\u4e2d\u7684ctDNA\u8131\u843d\u91cf\u6765\u9884\u6d4b\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u80bf\u7624\u7684\u5927\u5c0f\uff0c\u4e3a\u764c\u75c7\u5e38\u89c4\u7b5b\u67e5\u548c\u764c\u75c7\u590d\u53d1\u76d1\u6d4b\u63d0\u4f9b\u65b0\u7684\u7406\u8bba\u53c2\u8003\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>Stefano Avanzini et al., A mathematical model of ctDNA shedding predicts tumor detection size, Science Advances, 2020<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u8054\u5408\u7a7a\u95f4\u8f6c\u5f55\u7ec4<\/div>\n
\u63ed\u793a\u80ba\u635f\u4f24\u6cbb\u7597\u65b0\u9776\u70b9ADAMTS4<\/div>\n
\u8fd1\u65e5\uff0c\u7f8e\u56fdSt Jude\u513f\u7ae5\u533b\u9662\u7684Paul G. Thomas\u56e2\u961f\u8054\u5408\u5e7f\u5dde\u533b\u79d1\u5927\u5b66\u7b2c\u4e00\u9644\u5c5e\u533b\u9662\u949f\u5357\u5c71\u9662\u58eb\u56e2\u961f\u5728Nature\u671f\u520a\u4e0a\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u4ee5\u7532\u578b\u6d41\u611f\u75c5\u6bd2\u611f\u67d3\u5c0f\u9f20\u4e3a\u7814\u7a76ARDS\u7684\u6a21\u578b\uff0c\u7ed3\u5408\u5355\u7ec6\u80de\u6d4b\u5e8f\u548c\u7a7a\u95f4\u8f6c\u5f55\u7ec4\u7b56\u7565\uff0c\u53d1\u73b0\u5728\u75c5\u6bd2\u611f\u67d3\u8fc7\u7a0b\u4e2d\u8fc7\u5ea6\u6fc0\u6d3b\u7684\u6210\u7ea4\u7ef4\u7ec6\u80de\u53ef\u4ea7\u751f\u7ec6\u80de\u5916\u57fa\u8d28\u91cd\u5851\u9176\u2014\u5c24\u5176\u662fECM\u86cb\u767d\u9176ADAMTS4\uff0c\u91cd\u5851\u80ba\u90e8\u5fae\u73af\u5883\uff0c\u8fdb\u800c\u4fc3\u8fdb\u514d\u75ab\u7ec6\u80de\u6d78\u6da6\uff0c\u5bfc\u81f4\u80ba\u90e8\u529f\u80fd\u635f\u4f24\u3002\u6b64\u5916\uff0c\u53d1\u73b0ADAMTS4\u7684\u6c34\u5e73\u4e0e\u611f\u67d3\u7684\u4e25\u91cd\u7a0b\u5ea6\u6709\u5173\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>David F. Boyd et al., Exuberant fibroblast activity compromises lung function via ADAMTS4, Nature, 2022<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4e8e\u519b\u56e2\u961f\u53d1\u73b0\u539f\u6838\u751f\u7269\u57fa\u56e0\u7ec4\u91cd\u7ec4<\/div>\n
\u5728\u5927\u80a0\u6746\u83cc\u7269\u79cd\u5f62\u6210\u4e2d\u7684\u51b3\u5b9a\u4f5c\u7528<\/div>\n
12\u670815\u65e5\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u5317\u4eac\u57fa\u56e0\u7ec4\u7814\u7a76\u6240\u66a8\u56fd\u5bb6\u751f\u7269\u4fe1\u606f\u4e2d\u5fc3\u4e8e\u519b\u7814\u7a76\u56e2\u961f\uff0c\u5728\u751f\u7269\u4fe1\u606f\u5b66\u9886\u57df\u6742\u5fd7Briefings in Bioinformatics\u4e0a\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u901a\u8fc7\u4e8c\u4ee3\u548c\u4e09\u4ee3\u6d4b\u5e8f\u6570\u636e\uff0c\u5b8c\u6210\u4e86\u903e\u767e\u682a\u6765\u81ea\u4e16\u754c\u5404\u5730\u3001\u4e0d\u540c\u810a\u690e\u52a8\u7269\u5bbf\u4e3b\uff08\u5305\u62ec\u4eba\u7c7b\u5728\u5185\uff09\u7684\u5927\u80a0\u6746\u83cc\uff08E.coli\uff09\u9ad8\u7cbe\u51c6\u5ea6\u57fa\u56e0\u7ec4\u5b8c\u6210\u56fe\uff0c\u9610\u8ff0\u4e86\u57fa\u56e0\u7ec4\u91cd\u7ec4\u5728\u7269\u79cd\u5f62\u6210\u4e2d\u7684\u6838\u5fc3\u4f5c\u7528\u3002\uff08\u6d4b\u5e8f\u4e2d\u56fd\uff09<\/div>\n
\u53c2\u8003\u4fe1\u606f>>Yu Kang et al.,\u00a0A fine-scale map of genome-wide recombination in divergent Escherichia coli population,\u00a0Briefings in Bioinformatics,2020<\/div>\n
\u00a0<\/div>\n
\u5e94\u7528<\/div>\n
\u2756\u00a0\u6211\u56fd\u9996\u4e2a\u6807\u5fd7\u7269\u9a71\u52a8\u7684\u6cdb\u764c\u79cd\u836f\u7269<\/div>\n
\u4e0a\u5e02\u7533\u8bf7\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u6b63\u5f0f\u53d7\u7406<\/div>\n
12\u670822\u65e5\uff0c\u601d\u8def\u8fea\u533b\u836f\u5ba3\u5e03\uff0c\u4e0e\u5eb7\u5b81\u6770\u745e\u751f\u7269\u5236\u836f\u3001\u5148\u58f0\u836f\u4e1a\u96c6\u56e2\u6709\u9650\u516c\u53f8\u6218\u7565\u5408\u4f5c\u7684\u91cd\u7ec4\u4eba\u6e90\u5316PD-L1\u5355\u57df\u6297\u4f53\u6069\u6c83\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08\u7814\u53d1\u4ee3\u53f7\uff1aKN035\uff09\u7684\u65b0\u836f\u4e0a\u5e02\u7533\u8bf7(NDA)\u5df2\u4e8e12\u670817\u65e5\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u53d7\u7406\u3002<\/div>\n
\u8fd9\u662f\u4e2d\u56fd\u9996\u4e2a\u6807\u5fd7\u7269\u9a71\u52a8\u7684\u6cdb\u80bf\u7624\u836f\u7269\u3002\u76f8\u5173\u9002\u5e94\u75c7\u5305\u62ec\u65e2\u5f80\u6807\u51c6\u6cbb\u7597\u5931\u8d25\u7684\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\uff08MSI-H\uff09\/\u9519\u914d\u4fee\u590d\u529f\u80fd\u7f3a\u9677(dMMR) \u665a\u671f\u7ed3\u76f4\u80a0\u764c\u3001\u80c3\u764c\u53ca\u5176\u4ed6\u665a\u671f\u5b9e\u4f53\u7624\u3002\u6069\u6c83\u5229\u5355\u6297\u6ce8\u5c04\u6db2\uff08KN035\uff09\u662f\u5168\u7403\u9996\u4e2a\u76ae\u4e0b\u6ce8\u5c04\u7684PD-L1\u6291\u5236\u5242\uff0c\u83b7\u6279\u540e\u53ef\u586b\u8865\u672a\u88ab\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u82f1\u56fd\u65b0\u51a0\u75c5\u6bd2\u682a\u53d8\u5f02\uff0c\u5e73\u5747\u4f1a\u4f20\u67d31.5\u4eba<\/div>\n
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\u00a0<\/div>\n
\u2756\u00a0\u6211\u56fd\u9996\u4e2aSMA\u9057\u4f20\u5b66\u8bca\u65ad\u4e13\u5bb6\u5171\u8bc6\u53d1\u5e03\u53ca\u89e3\u8bfb<\/div>\n
12\u670827\u65e5\uff0c\u9057\u4f20\u75c5\u8bca\u65ad\u53d1\u5c55\u8bba\u575b\u66a8SMA\u9057\u4f20\u5b66\u8bca\u65ad\u4e13\u5bb6\u5171\u8bc6\u89e3\u8bfb\u4f1a\u53ec\u5f00\u3002\u6b64\u5171\u8bc6\u662f\u9996\u90fd\u513f\u79d1\u7814\u7a76\u6240\u9057\u4f20\u7814\u7a76\u5ba4\u5b8b\u6609\u7814\u7a76\u5458\u57282020\u5e74\u75ab\u60c5\u671f\u95f4\uff0c\u7275\u5934\u7ec4\u7ec7\u5168\u56fd\u591a\u5bb6\u533b\u9662\u591a\u5b66\u79d1\u4e13\u5bb6\u56e2\u961f\u5171\u540c\u64b0\u5199\u4e86\u6211\u56fd\u7b2c\u4e00\u4e2a\u201c\u810a\u9ad3\u6027\u808c\u840e\u7f29\u75c7\u9057\u4f20\u5b66\u8bca\u65ad\u4e13\u5bb6\u5171\u8bc6\u201d\uff0c\u53d1\u8868\u5728\u300a\u4e2d\u534e\u533b\u5b66\u6742\u5fd7\u300b2020\u5e7411\u67083\u65e5\u7b2c100\u5377\u7b2c40\u671f\u3002<\/div>\n
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\u00a0<\/div>\n
\u5173\u4e8e\u57fa\u56e0\u6167\u00a0<\/div>\n
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