{"id":8963,"date":"2021-01-10T12:20:53","date_gmt":"2021-01-10T04:20:53","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100017987&idx=1&sn=bbc96d0501748a36a13e9adbb8d7e6a1&chksm=6b7175f45c06fce2d89ba867e1e5d7f18d75eca4b4355acf7b59d6feb6c7e5b46fd3b87a8789#rd"},"modified":"2026-04-01T16:09:57","modified_gmt":"2026-04-01T08:09:57","slug":"529957","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2021\/01\/10\/529957\/","title":{"rendered":"\u57fa\u56e0\u7b80\u62a5 | 1\u7bc7\u6587\u7ae0\u63a8\u52a8\u516c\u53f8\u5e02\u503c\u589e\u52a040\u4ebf\uff1b\u7b2c39\u5c4aJPM\u5927\u4f1a\u5373\u5c06\u5f00\u59cb"},"content":{"rendered":"
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\"RmFicvQBAkgCyQ3CmPaIgCucVGbl58tVvBvKDYRjiaBZGIgd9sDnAtvxaWpKum2kTyWKQDTichibs1iaEaDhibO7YZQg\"\/<\/figure><\/div>\n\n
\u653f\u7b56<\/div>\n
\u2756\u00a0\u82cf\u5dde\u5e02\u8bbe\u7acb\u5929\u4f7f\u6295\u8d44\u5f15\u5bfc\u57fa\u91d1\uff0c<\/div>\n
\u57fa\u91d1\u89c4\u6a2160\u4ebf\u5143<\/div>\n
1\u67084\u65e5\uff0c\u82cf\u5dde\u5e02\u5929\u4f7f\u6295\u8d44\u5f15\u5bfc\u57fa\u91d1\u63ed\u724c\uff0c\u57fa\u91d1\u89c4\u6a21\u8fbe60\u4ebf\u5143\uff0c\u7528\u4e8e\u63a8\u52a8\u521b\u65b0\u521b\u4e1a\u3001\u4fc3\u8fdb\u4ea7\u4e1a\u8f6c\u578b\u3001\u52a0\u5feb\u4ea7\u4e1a\u6210\u957f\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/OO9Qk132T8NWjxVGeFZmTQ<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u6df1\u5733\u6700\u9ad8\u5956\u52b12000\u4e07\u5143\uff0c<\/div>\n
\u6276\u6301\u80a1\u6743\u6295\u8d44\u673a\u6784\u53d1\u5c55<\/div>\n
\u8fd1\u65e5\uff0c\u6df1\u5733\u5e02\u5730\u65b9\u91d1\u878d\u76d1\u7ba1\u5c40\u53d1\u5e03\u4e86\u300a\u5173\u4e8e\u4fc3\u8fdb\u6df1\u5733\u80a1\u6743\u6295\u8d44\u6301\u7eed\u9ad8\u8d28\u91cf\u53d1\u5c55\u7684\u82e5\u5e72\u63aa\u65bd\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b\uff0c\u5bf9\u4e8e\u9f13\u52b1\u80a1\u6743\u6295\u8d44\u5404\u7c7b\u5e02\u573a\u4e3b\u4f53\u5728\u6df1\u53d1\u5c55\u6709\u8d21\u732e\u7684\u4e2a\u4eba\u6216\u673a\u6784\u7ed9\u4e88\u73b0\u91d1\u5956\u52b1\uff0c\u6700\u9ad8\u5956\u52b12000\u4e07\u5143\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/Gt3VOwO5n1SWbYkhk7E5AA<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u57c3\u53ca\u6279\u51c6\u4f7f\u7528\u4e2d\u56fd\u65b0\u51a0\u75ab\u82d7<\/div>\n
\u636e\u4eba\u6c11\u65e5\u62a5\u8baf\uff0c\u57c3\u53ca\u536b\u751f\u4e0e\u4eba\u53e3\u90e8\u90e8\u957f\u54c8\u62c9\u00b7\u624e\u8036\u5fb71\u67082\u65e5\u665a\u8868\u793a\uff0c\u57c3\u53ca\u6b63\u5f0f\u6279\u51c6\u5728\u57c3\u7d27\u6025\u4f7f\u7528\u4e2d\u56fd\u56fd\u836f\u96c6\u56e2\u65b0\u51a0\u75c5\u6bd2\u706d\u6d3b\u75ab\u82d7\u3002\u636e\u57c3\u53ca\u6700\u5927\u7684\u65b0\u95fb\u673a\u6784\uff0cAl-Ahram Establishment \u5728\u7ebf\u82f1\u6587\u7f51\u7ad9\u62ab\u9732\uff0c\u75ab\u82d7\u63a5\u79cd\u5c06\u4e8e1\u6708\u5f00\u59cb\u3002<\/div>\n\n
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\"0?wx_fmt=png\"\/<\/figure><\/div>\n\n
\u56fe\/\u57c3\u53ca\u6279\u51c6\u7d27\u6025\u4f7f\u7528\u4e2d\u56fd\u56fd\u836f\u75ab\u82d7\uff0c<\/div>\n
\u75ab\u82d7\u63a5\u79cd\u5c06\u4e8e1\u6708\u5f00\u59cb<\/div>\n
\uff08\u6765\u6e90\uff1aAhram Online\uff09<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/wap.peopleapp.com\/article\/6095835\/6006267<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u70b9\u53d1\u5e03<\/div>\n
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1\u67087\u65e5\uff0c\u56fd\u5bb6\u536b\u751f\u5065\u5eb7\u59d4\u5ba3\u4f20\u53f8\u4e0e\u817e\u8baf\u5065\u5eb7\u8054\u5408\u53d1\u5e03\u201c\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u70b9\u5730\u56fe\u201d\uff0c\u7528\u6237\u53ef\u5728\u201c\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u70b9\u5730\u56fe\u201d\u4e0a\u67e5\u8be2\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u70b9\u4e00\u89c8\uff0c\u5e76\u4fbf\u6377\u5730\u5bfc\u822a\u81f3\u8ddd\u79bb\u6700\u8fd1\u7684\u63a5\u79cd\u70b9\uff0c\u4e3a\u63a5\u79cd\u8005\u6709\u5e8f\u5b89\u6392\u65b0\u51a0\u80ba\u708e\u75ab\u82d7\u63a5\u79cd\u63d0\u4f9b\u4fbf\u5229\u3002\u540c\u65f6\uff0c\u6240\u6709\u7b26\u5408\u8d44\u8d28\u7684\u516c\u4f17\u53f7\u3001\u5c0f\u7a0b\u5e8f\u3001APP\u5747\u53ef\u7533\u8bf7\u63a5\u5165\u201c\u65b0\u51a0\u75ab\u82d7\u63a5\u79cd\u70b9\u5730\u56fe\u201d\uff0c\u5e2e\u52a9\u66f4\u591a\u6709\u9700\u8981\u7684\u4eba\u3002<\/div>\n\n
\u3010\u626b\u7801\u76f4\u8fbe\u201d\u75ab\u82d7\u63a5\u79cd\u5730\u56fe\u201c\u3011<\/div>\n\n
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\"VYwTtzwHpUjThiaZRvs0yuAMAkM0l68PM1pqt8mbIhT4JWBZ26pqe4cWfqEF25TGibDDAxaJY7AZU7p3gtmuicqgg\"\/<\/figure><\/div>\n\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/crM99mn3Cw57jz82GgWP3A<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4e16\u536b\u7ec4\u7ec7\u547c\u5401\u6240\u6709\u56fd\u5bb6<\/div>\n
\u589e\u52a0\u75c5\u6bd2\u68c0\u6d4b\u548c\u57fa\u56e0\u6d4b\u5e8f<\/div>\n
1\u67085\u65e5\uff0c\u4e16\u536b\u7ec4\u7ec7\u5728\u65b0\u51a0\u80ba\u708e\u4f8b\u884c\u53d1\u5e03\u4f1a\u4e0a\u547c\u5401\u6240\u6709\u56fd\u5bb6\u589e\u52a0\u75c5\u6bd2\u68c0\u6d4b\u548c\u57fa\u56e0\u6d4b\u5e8f\uff0c\u4ee5\u76d1\u6d4b\u548c\u5e94\u5bf9\u4efb\u4f55\u53d8\u5316\uff0c\u5404\u56fd\u5e94\u57fa\u4e8e\u6d41\u884c\u75c5\u5b66\u60c5\u51b5\u91c7\u53d6\u9002\u5f53\u63aa\u65bd\u3002<\/div>\n
\u636e\u7f8e\u56fd\u7ea6\u7ff0\u65af\u00b7\u970d\u666e\u91d1\u65af\u5927\u5b66\u7edf\u8ba1\uff0c\u622a\u81f3\u5317\u4eac\u65f6\u95f46\u65e57\u65f623\u5206\uff0c\u5168\u7403\u65b0\u51a0\u786e\u8bca\u75c5\u4f8b\u8fbe86230870\u4f8b\uff0c\u6b7b\u4ea1\u75c5\u4f8b\u4e3a1865267\u4f8b\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/e2I8lnXJeWehKxrItnr7yQ<\/div>\n
\u4ea7\u4e1a<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u8d1d\u8fbe\u836f\u4e1a\u62df\u7533\u8bf7\u6e2f\u80a1\u4e0a\u5e02<\/div>\n
1\u67087\u65e5\uff0c\u8d1d\u8fbe\u836f\u4e1a\u53d1\u5e03\u516c\u544a\u79f0\uff0c\u516c\u53f8\u62df\u53d1\u884c\u5883\u5916\u4e0a\u5e02\u5916\u8d44\u80a1\uff08H\u80a1\uff09\uff0c\u5e76\u7533\u8bf7\u5728\u9999\u6e2f\u8054\u5408\u4ea4\u6613\u6240\u6709\u9650\u516c\u53f8\u4e3b\u677f\u6302\u724c\u4e0a\u5e02\uff0c\u540c\u65f6\u516c\u53f8\u8f6c\u4e3a\u5883\u5916\u52df\u96c6\u80a1\u4efd\u6709\u9650\u516c\u53f8\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/ggjd.cnstock.com\/company\/scp_ggjd\/tjd_ggkx\/202101\/4641705.htm<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4e98\u559c\u751f\u7269\u7f8e\u80a1\u4e0a\u5e02\uff1a\u5e02\u503c16\u4ebf\u7f8e\u5143<\/div>\n
1\u67088\u65e5\uff0c\u4e98\u559c\u751f\u7269\uff08Gracell Biotechnologies\uff09\u6b63\u5f0f\u5728\u7f8e\u56fd\u7eb3\u65af\u8fbe\u514b\u4e0a\u5e02\uff0c\u53d1\u884c\u4ef7\u4e3a19\u7f8e\u5143\uff0c\u52df\u8d44\u603b\u989d2\u4ebf\u7f8e\u5143\u3002\u4e0a\u5e02\u5f53\u5929\u65e5\u5f00\u76d8\u4ef7\u4e3a26\u7f8e\u5143\uff0c\u8f83\u53d1\u884c\u4ef7\u4e0a\u6da836.84%\uff1b\u6536\u76d8\u4ef7\u4e3a25.06\u7f8e\u5143\uff0c\u8f83\u53d1\u884c\u4ef7\u4e0a\u6da831.89%\uff1b\u4ee5\u6536\u76d8\u4ef7\u8ba1\u7b97\uff0c\u5e02\u503c\u4e3a16.43\u4ebf\u7f8e\u5143\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.163.com\/dy\/article\/FVTOLNLT0511A0EF.html<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Editas Medicine\u516c\u53f8\u80a1\u7968\u76f4\u7ebf\u4e0a\u6da810%<\/div>\n
\u5e02\u503c\u589e\u52a040\u4ebf<\/div>\n
1\u67086\u65e5\uff0c\u57fa\u56e0\u7f16\u8f91\u9886\u57df\u5927\u725bDavid Liu\u5728Nature\u5728\u7ebf\u53d1\u8868\u9898\u4e3a\u201dIn vivo\u00a0base editing rescues Hutchinson\u2013Gilford progeria syndrome in mice\u201c\u7684\u7814\u7a76\u8bba\u6587\uff0c\u63ed\u793a\u4f53\u5185\u78b1\u57fa\u7f16\u8f91\u4f5c\u4e3a\u65e9\u8870\u7efc\u5408\u75c7\uff08HGPS\uff09\u548c\u5176\u4ed6\u9057\u4f20\u75be\u75c5\u7684\u53ef\u80fd\u6cbb\u7597\u65b9\u6cd5\u7684\u6f5c\u529b\u3002\u6587\u7ae0\u53d1\u8868\u540e\uff0c\u5f20\u950b\u3001David Liu\u7b49\u4eba\u7684Editas Medicine\u516c\u53f8\u80a1\u7968\u76f4\u7ebf\u4e0a\u6da8\uff0c\u4ec51\u67087\u65e5\u4e00\u5929\u6da8\u5e45\u8fd110%\uff0c\u5e02\u503c\u589e\u52a0\u4e8640\u4ebf\u4eba\u6c11\u5e01\u3002<\/p>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41586-020-03086-7<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u7b2c39\u5c4aJPM\u5927\u4f1a\u5373\u5c06\u5f00\u59cb<\/div>\n
\u5168\u7403\u89c4\u6a21\u6700\u5927\u3001\u4fe1\u606f\u91cf\u6700\u4e30\u5bcc\u3001\u53d7\u5173\u6ce8\u7a0b\u5ea6\u6700\u9ad8\u7684\u533b\u5065\u6295\u8d44\u5927\u4f1a\u2014\u2014\u7b2c39\u5c4a\u6469\u6839\u5927\u901a\u533b\u7597\u5065\u5eb7\u5927\u4f1a\u62df\u4e8e1\u670811\u65e5-14\u65e5\u5f00\u542f\u3002\u5c4a\u65f6\uff0c\u57fa\u56e0\u6167\u5c06\u5168\u7a0b\u4e3a\u60a8\u8ddf\u8e2a\u5927\u4f1a\u70ed\u70b9\u4fe1\u606f\uff0c\u656c\u8bf7\u5173\u6ce8\u3002<\/div>\n<\/div>\n\n
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\"RmFicvQBAkgCV1GTUiaZLM90a4xV2Yl27G14EURNsib0e4yE8N2qUqKwmobzrwiaicK7lVNPUicsgRspVcCRJwVNtjdw\"\/<\/figure><\/div>\n\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.jpmorgan.com<\/div>\n
<\/div>\n
<\/div>\n<\/p>\n
\u2756\u00a0\u4e0a\u5468\u91cd\u5927\u5408\u4f5c\u4e8b\u4ef6<\/div>\n
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\"RmFicvQBAkgA9dQMeQZmx99J8iaKzHw9gQDicial60JdibtrcAfLVJ4mjCaw8Q5hTI6kaNs65fIbUia0EJsGJahjuntQ\"\/<\/figure><\/div>\n\n<\/div>\n
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\u2756\u4e0a\u5468\u91cd\u5927\u878d\u8d44\u4e8b\u4ef6<\/div>\n
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\"RmFicvQBAkgA9dQMeQZmx99J8iaKzHw9gQ5rDQpQQEkKzbVpq9MuZOeIKjtPDuJyVzsob15do0kpTE1icicliatEhicw\"\/<\/figure><\/div>\n\n
\u6280\u672f<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4e0a\u4ea4\u5927\u79d1\u7814\u56e2\u961f\u53d1\u660eVLP\u9012\u9001\u6280\u672f<\/div>\n
\u52a9\u529b\u4f53\u5185\u57fa\u56e0\u7f16\u8f91\u6cbb\u7597\u8d70\u5411\u4e34\u5e8a<\/div>\n
2021\u5e741\u67084\u65e5\uff0c\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u7cfb\u7edf\u751f\u7269\u533b\u5b66\u7814\u7a76\u9662\u7684\u8521\u5b87\u5496\u56e2\u961f\u5728Nature Biomedical Engineering\u6742\u5fd7\u4e0a\u53d1\u8868\u7814\u7a76\u8bba\u6587\u3002\u5176\u56e2\u961f\u901a\u8fc7\u75c5\u6bd2\u5de5\u7a0b\u6280\u672f\u521b\u9020\u7684VLP-mRNA\u9012\u9001\u6280\u672f\u53ef\u4ee5\u663e\u8457\u964d\u4f4e\u3001\u751a\u81f3\u5b8c\u5168\u907f\u514d\u8131\u9776\u6548\u5e94\uff0c\u5e76\u4e14\u8fd0\u8f7d\u80fd\u529b\u5f3a\uff0c\u53ef\u4ee5\u9012\u9001\u66f4\u5927\u7684\u78b1\u57fa\u7f16\u8f91\u5de5\u5177\u3002\u7814\u7a76\u56e2\u961f\u5728\u8bd5\u9a8c\u4e2d\u5c06\u6b64\u9879\u65b0\u6280\u672f\u7528\u4e8e\u5c0f\u9f20\u6a21\u578b\u7684\u9ec4\u6591\u53d8\u6027\u6cbb\u7597\uff0c\u7ed3\u679c\u8868\u660e\uff0c\u4f7f\u7528VLP\u9012\u9001\u6280\u672f\u8fdb\u884c\u7684\u57fa\u56e0\u7f16\u8f91\u6cbb\u7597\u6548\u679c\u660e\u663e\uff0c\u5e76\u672a\u8bf1\u5bfc\u51fa\u8131\u9776\u6548\u5e94\uff0c\u4e14\u672a\u80fd\u5f15\u8d77\u514d\u75ab\u53cd\u5e94\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>Lentiviral delivery of co-packaged Cas9 mRNA and a Vegfa-targeting guide RNA prevents wet age-related macular degeneration in mice<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0GTEx\u6570\u636e\u5e93\u73b0\u53ef\u514d\u8d39\u4e0b\u8f7d<\/div>\n
\u4e0a\u5468\uff0c\u829d\u52a0\u54e5\u2013\u7f8e\u56fd\u56fd\u5bb6\u4eba\u7c7b\u57fa\u56e0\u7ec4\u7814\u7a76\u6240\uff08NHGRI\uff09\u5ba3\u5e03\uff0c\u5176\u57fa\u56e0\u578b\u7ec4\u7ec7\u8868\u8fbe\uff08GTEx\uff09\u6570\u636e\u5e93\u73b0\u5728\u53ef\u4ee5\u901a\u8fc7\u4e91\u5e73\u53f0\u514d\u8d39\u4e0b\u8f7d\u3002GTEx\u6570\u636e\u5e93\u53ef\u5bf9\u6765\u81ea\u4eba\u4f53\u591a\u4e2a\u7ec4\u5408\u548c\u5668\u5b98\u7684\u6837\u672c\u540c\u65f6\u8fdb\u884c\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u548c\u57fa\u56e0\u5206\u578b\u5206\u6790\uff0c\u6784\u5efa\u4e86\u4e00\u4e2a\u7ec4\u7ec7\u7279\u5f02\u6027\u7684\u57fa\u56e0\u8868\u8fbe\u548c\u8c03\u63a7\u7684\u6570\u636e\u5e93\u3002<\/div>\n
GTEx\u6570\u636e\u5e93\u7f51\u5740\uff1a<\/div>\n
https:\/\/gtexportal.org\/home\/<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.genomeweb.com\/informatics\/anvil-platform-makes-popular-nhgri-gtex-database-free-download#.X_mJkegzZPa<\/div>\n
\u00a0<\/div>\n
\u5e94\u7528<\/div>\n
\u2756\u00a0\u56fd\u5185\u7b2c\u4e8c\u4e2a\u81ea\u4e3b\u7814\u53d1mRNA\u65b0\u51a0\u75ab\u82d7\u83b7\u6279\u4e34\u5e8a<\/div>\n
2021\u5e741\u67085\u65e5\uff0c\u6839\u636e\u897f\u85cf\u836f\u4e1a\uff08600211\uff09\u53d1\u5e03\u7684\u516c\u544a\uff0c\u5176\u5408\u4f5c\u65b9\u65af\u5fae\u751f\u7269\u81ea\u4e3b\u7814\u53d1\u7684mRNA\u65b0\u51a0\u75ab\u82d7\u5df2\u6536\u5230\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u6838\u51c6\u7b7e\u53d1\u7684\u300a\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u6279\u4ef6\u300b\u3002\u4f9d\u7167\u5408\u4f5c\u534f\u8bae\uff0c\u897f\u85cf\u836f\u4e1a\u5c06\u5411\u65af\u5fae\u751f\u7269\u652f\u4ed8\u76f8\u5e94\u6ce8\u518c\u91cc\u7a0b\u7891\u6b3e3500\u4e07\u5143\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/sApkXLiVFKS7ckjjsu494w<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u6cdb\u80bf\u7624\u9776\u5411\u836f\u7269SIM1803-1A\u7247<\/div>\n
\u5728\u4e2d\u56fd\u5b8c\u6210\u9996\u4f8b\u53d7\u8bd5\u8005\u7ed9\u836f<\/div>\n
2021\u5e741\u67085\u65e5\uff0c\u7531\u5148\u58f0\u836f\u4e1a\u6709\u9650\u516c\u53f8\u7814\u53d1\u7684NTRK\/ROS1\u591a\u9776\u70b9\u6291\u5236\u5242SIM1803-1A\u7247\uff0c\u5728\u4e2d\u56fd\u5b8c\u6210I\u671f\u4e34\u5e8a\u8bd5\u9a8c\u9996\u4f8b\u53d7\u8bd5\u8005\u7684\u9996\u6b21\u7ed9\u836f\u3002\u636e\u6089\uff0c\u56fd\u5185\u5c1a\u65e0\u6025\u4e8e\u57fa\u56e0\u7a81\u53d8\u3001\u4e0d\u9650\u80bf\u7624\u53d1\u75c5\u90e8\u4f4d\u7684\u6cdb\u80bf\u7624\u9776\u5411\u836f\u7269\u83b7\u6279\u3002\u65b0\u4e00\u4ee3\u7cbe\u51c6\u6cbb\u7597\u836f\u7269SIM1803-1A\u7247\u6216\u5c06\u6210\u4e3a\u56fd\u5185\u9996\u6279\u6cdb\u80bf\u7624\u6297\u764c\u836f\u7269\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/yRrt1Vvm7EJ_Q8Y2NZVvfA<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Passage Bio\u516c\u53f8AAV\u57fa\u56e0\u7597\u6cd5\u836f\u7269<\/div>\n
\u83b7\u6279\u8fdb\u5165\u7f8e\u56fd\u4e34\u5e8a\u8bd5\u9a8c<\/div>\n
\u8fd1\u65e5\uff0c\u7f8e\u56fdFDA\u6279\u51c6Passage Bio\u516c\u53f8\u7684AAV\u57fa\u56e0\u7597\u6cd5\u5019\u9009\u836f\u7269PBGM01\u7684IND\u7533\u8bf7\uff0c\u4ee5\u7528\u4e8e\u5f00\u5c55\u9488\u5bf9\u5a74\u513f\u578bGM1\u795e\u7ecf\u8282\u82f7\u8102\u8d2e\u79ef\u75c7\uff08GM1 gangliosidosis\uff09\u7684\u4e34\u5e8a\u8bd5\u9a8c\u3002\u6b64\u524d\uff0c\u8be5\u836f\u7269\u5df2\u7ecf\u83b7\u5f97\u4e86\u82f1\u56fd\u533b\u836f\u4fdd\u5065\u4ea7\u54c1\u76d1\u7ba1\u5c40\uff08MHRA\uff09\u4e34\u5e8a\u8bd5\u9a8c\u6388\u6743\uff0c\u5141\u8bb8\u5728\u82f1\u56fd\u5f00\u5c55\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/investors.passagebio.com\/news-releases\/news-release-details\/passage-bio-receives-fda-clearance-ind-application-lead-gene<\/div>\n
\u62d3\u5c55\u9605\u8bfb<\/div>\n
GeneMail No.127\u2014\u2014\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u884c\u4e1a\u7b80\u62a5<\/a>\u6cdb\u751f\u5b50\u4e0e\u4e2d\u56fd\u751f\u7269\u5236\u836f\u5b50\u516c\u53f8\u8fbe\u6210\u72ec\u5bb6\u6218\u7565\u5408\u4f5c\u5173\u7cfb<\/a>\u5b8f\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u7a81\u7834\u4f20\u7edf\u8bca\u65ad\u65b9\u6cd5\u5c40\u9650\u6027<\/a><\/div>\n
\u3010\u58f0\u660e\u3011\u4e3a\u4f20\u64ad\u79d1\u5b66\u4fe1\u606f\uff0c\u63a8\u52a8\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u5b66\u7814\u8fde\u63a5\uff0c\u6211\u4eec\u79c9\u6301\u4e2d\u7acb\u3001\u4e13\u4e1a\u3001\u8d4b\u80fd\u7684\u7406\u5ff5\u6536\u96c6\u3001\u5206\u6790\u6216\u53d1\u5e03\u4fe1\u606f\u3002\u4f46\u7531\u4e8e\u65f6\u6548\u6027\u53ca\u884c\u4e1a\u7279\u6b8a\u6027\uff0c\u6240\u520a\u767b\u5185\u5bb9\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u4e0d\u4f5c\u4e3a\u51b3\u7b56\u4f9d\u636e\uff1b\u672c\u6587\u76f8\u5173\u4fe1\u606f\u4e0d\u4ee3\u8868\u57fa\u56e0\u6167\u673a\u6784\u7684\u89c2\u70b9\uff1b\u201c\u57fa\u56e0\u6167\u201d\u520a\u767b\u7684\u539f\u521b\u5185\u5bb9\u7684\u77e5\u8bc6\u4ea7\u6743\u4e3a\u201c\u57fa\u56e0\u6167\u201d\u5546\u6807\u62e5\u6709\u8005\u53ca\u76f8\u5173\u6743\u5229\u4eba\u6240\u6709\uff1b\u6b22\u8fce\u8f6c\u8f7d\uff0c\u8f6c\u8f7d\u8bf7\u7533\u8bf7\u5e76\u6ce8\u660e\u6765\u6e90\u3002\u6b22\u8fce\u4e2a\u4eba\u53ca\u673a\u6784\u6295\u7a3f\u53ca\u5408\u4f5c\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u5173\u4e8e\u57fa\u56e0\u6167\u00a0<\/div>\n
\u57fa\u56e0\u6167\u662f\u6570\u5b57\u751f\u547d\u5065\u5eb7\u9886\u57df\u521b\u65b0\u670d\u52a1\u5e73\u53f0\u3002\u56e2\u961f\u6df1\u8015\u884c\u4e1a\u5341\u4f59\u5e74\uff0c\u4ece\u884c\u7814\u54a8\u8be2\u3001\u5a92\u4f53\u8d44\u8baf\u3001\u4ea7\u4e1a\u5e73\u53f0\u7b49\u89d2\u5ea6\u63d0\u4f9b\u4f18\u8d28\u5185\u5bb9\u3002\u4f5c\u4e3a\u56fd\u53d1\u6539\u4ea7\u4e1a\u7814\u7a76\u5408\u4f5c\u5355\u4f4d\uff0c\u57fa\u56e0\u6167\u8054\u5408\u591a\u5bb6\u5934\u90e8\u673a\u6784\u8fde\u7eed\u56db\u5e74\u53d1\u5e03\u516c\u5f00\u7684\u884c\u7814\u62a5\u544a\uff0c\u4e3a\u4ea7\u4e1a\u56ed\u3001\u6295\u8d44\u673a\u6784\u3001\u5934\u90e8\u4f01\u4e1a\u53ca\u653f\u5e9c\u63d0\u4f9b\u54a8\u8be2\u89c4\u5212\u670d\u52a1\uff0c\u53c2\u4e0e\u7ec4\u7ec7\u53d1\u5e03\u884c\u4e1a\u5171\u8bc6\u548c\u6807\u51c6\uff0c\u81f4\u529b\u4e8e\u5efa\u8bbe\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u6570\u5b57\u5316\u5e73\u53f0\uff0c\u670d\u52a1\u751f\u547d\u79d1\u6280\u521b\u65b0\u521b\u4e1a\u3002<\/div>\n
\u2606\u00a0\u56fd\u53d1\u6539\u300a\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b\u7f16\u59d4<\/a><\/div>\n
\u2606\u00a0\u53c2\u4e0e\u7ec4\u7ec7\u53d1\u5e03\u884c\u4e1a\u5171\u8bc6<\/a>\u3001\u56e2\u4f53\u6807\u51c6<\/a><\/div>\n
\u2606\u00a0\u53d1\u5e03\u4ea7\u4e1a\u5927\u6570\u636e\u5e73\u53f0\u4f18\u8109\u901aYourMap<\/a><\/div>\n
\u2606\u4e2d\u56fd\u9057\u4f20\u5b66\u4f1a\u751f\u7269\u4ea7\u4e1a\u4fc3\u8fdb\u59d4\u5458\u4f1a\u59d4\u5458<\/div>\n
\u2606\u00a0\u53d1\u5e03\u6570\u5341\u4efd\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u9886\u57df\u884c\u7814\u62a5\u544a<\/a><\/div>\n
\u2606\u00a0\u7ec4\u7ec7\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\uff08\u7b79\uff09\u9996\u5c4a<\/a>\u3001\u7b2c\u4e8c\u5c4a<\/a>\u4f1a\u8bae<\/a><\/div>\n
\u2606\u00a0\u4e3b\u529e\u6570\u5b57\u5065\u5eb7\u79c1\u8463\u4f1a<\/a>\u3001\u5927\u6e7e\u533a\u751f\u547d\u5065\u5eb7\u521b\u65b0\u8bba\u575b<\/a><\/div>\n
\u2606\u00a0\u53d7\u9080\u4e3a\u534e\u897f<\/a>\u3001Illumina<\/a>\u3001\u534e\u5927<\/a>\u3001\u4e0a\u6d77\u4ea4\u5927<\/a>\u7b49\u62a5\u544a<\/div>\n
\u2606\u00a0\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u80bf\u7624\u6807\u5fd7\u4e13\u4e1a\u59d4\u5458\u4f1a\u6218\u7565\u5408\u4f5c\u5355\u4f4d<\/a><\/div>\n
\u2606\u00a0\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5e94\u7528\u5b66\u4f1a\u653f\u7b56\u7814\u7a76\u5e94\u7528\u5206\u4f1a\u5e38\u52a1\u59d4\u5458<\/div>\n\n
\n
\"RmFicvQBAkgAeFMK0ia5Cab3334OUN1mUBG4bibxEzJJC01MPtSxIgRZcJvf6IGrU6cWAaTKdqM8GkEbzxEfFiaWCQ\"\/<\/figure><\/div>\n\n
<\/div>\n
<\/div>\n
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