\u00a0<\/div>\n
\u6587\u7ae0 | \u57fa\u56e0\u6167\u7f16\u8f91 | Vladmir\u00a0\u5ba1\u6838 | Sharon<\/div>\n
\u00a0<\/div>\n
\u8fd1\u65e5\u201c2021\u4e2d\u56fd\u56fd\u9645\u533b\u7597\u5668\u68b0\u535a\u89c8\u4f1a(CMEF)\u201d\u4e0a\uff0c\u4e00\u6279\u56fd\u4ea7\u54c1\u724c\u5927\u653e\u5f02\u5f69\u3002\u56fd\u5185\u9ad8\u7aef\u533b\u7597\u5668\u68b0\u9886\u57df\u7684\u683c\u5c40\u6b63\u5728\u53d1\u751f\u6539\u53d8\u30022020\u5e74\u4e0a\u534a\u5e74\u6211\u56fd\u533b\u7597\u5668\u68b0\u8fdb\u53e3\u51fa\u73b0\u4e86\u8d1f\u589e\u957f\uff0c\u4eca\u5e74\u5e7f\u4e1c\u548c\u6d59\u6c5f\u7701\u516c\u5e03\u7684\u91c7\u8d2d\u8fdb\u53e3\u4ea7\u54c1\u76ee\u5f55\u6e05\u5355\u4e5f\u51fa\u73b0\u4e0b\u964d\uff0c\u5c24\u5176\u662f\u5e7f\u4e1c\u8fdb\u53e3\u533b\u7597\u8bbe\u5907\u6e05\u5355\u9aa4\u964d\u4e86\u4e09\u5206\u4e4b\u4e8c\u3002\u672c\u6587\u5c06\u4ece\u653f\u7b56\u548c\u5e02\u573a\u65b9\u9762\u6765\u6d45\u6790\u57fa\u56e0\u884c\u4e1a\u9ad8\u7aef\u533b\u7597\u8bbe\u5907\u56fd\u4ea7\u66ff\u4ee3\u7684\u53d1\u5c55\u60c5\u51b5\u3002<\/div>\n
\u00a0<\/div>\n
\u4e58\u653f\u7b56\u4e1c\u98ce\uff0c\u56fd\u4ea7\u66ff\u4ee3\u6b65\u4f10\u52a0\u5feb<\/div>\n\n
\n![\"RmFicvQBAkgD4SG8Rj9JODMxFP7Lb4dz6t5cBSSfgT0icJKgqWk9nok5Aq6EdXBttoyvF9QzNcYRer1czAMX1SAg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgD4SG8Rj9JODMxFP7Lb4dz6t5cBSSfgT0icJKgqWk9nok5Aq6EdXBttoyvF9QzNcYRer1czAMX1SAg.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u88681\uff1a\u9ad8\u7aef\u533b\u7597\u88c5\u5907\u56fd\u4ea7\u5316\u76f8\u5173\u653f\u7b56\uff08\u6765\u6e90\/\u57fa\u56e0\u6167\u6574\u7406\uff09<\/div>\n
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\u00a0<\/div>\n
\u90e8\u5206\u7701\u5e02\u4e5f\u5bf9\u56fd\u4ea7\u533b\u7597\u5668\u68b0\u8868\u73b0\u51fa\u660e\u663e\u503e\u659c\uff0c\u5e7f\u4e1c\u548c\u6d59\u6c5f\u4eca\u5e74\u8fdb\u53e3\u533b\u7597\u8bbe\u5907\u6e05\u5355\u662f\u51cf\u5c11\u7684\uff0c\u5c24\u5176\u662f\u5e7f\u4e1c\u7701\u51fa\u73b0\u4e86\u5927\u5e45\u4e0b\u964d\uff0c\u5728\u53d1\u5e03\u7684\u6700\u65b0\u8fdb\u53e3\u4ea7\u54c1\u76ee\u5f55\u6e05\u5355\u4e2d\uff0c\u53ef\u9009\u62e9\u8fdb\u53e3\u533b\u7597\u8bbe\u5907\u54c1\u79cd\u4ece132\u79cd\u964d\u81f346\u79cd\u3002\u800c\u56db\u5ddd\u7701\u5141\u8bb8\u91c7\u8d2d\u7684\u8fdb\u53e3\u533b\u7597\u8bbe\u5907\u662f\u589e\u52a0\u7684\uff0c\u5168\u81ea\u52a8\u6838\u9178\u68c0\u6d4b\u5206\u6790\u4eea\u3001\u57fa\u56e0\u6d4b\u5e8f\u4eea\u3001\u81ea\u52a8\u5316\u591a\u901a\u9053\u79fb\u6db2\u5de5\u4f5c\u7ad9\u7b49\u751f\u547d\u79d1\u5b66\u8bbe\u5907\u51fa\u73b0\u5728\u65b0\u589e\u7701\u7ea7\u653f\u5e9c\u91c7\u8d2d\u8fdb\u53e3\u4ea7\u54c1\u4e2d\u3002\u9ad8\u901a\u91cf\u57fa\u56e0\u6d4b\u5e8f\u4eea\u57282019\u5e74\u5df2\u4ece\u5e7f\u4e1c\u7701\u5141\u8bb8\u91c7\u8d2d\u7684\u8fdb\u53e3\u533b\u7597\u8bbe\u5907\u6e05\u5355\u4e2d\u79fb\u9664\u3002<\/div>\n
\u00a0<\/div>\n
\u201c\u53cc\u5faa\u73af\u201d\u5c06\u91cd\u6784\u9ad8\u7aef\u533b\u7597\u8bbe\u5907\u5e02\u573a\u683c\u5c40\uff1f<\/div>\n
\u5728\u5f53\u524d\u590d\u6742\u7684\u56fd\u5185\u5916\u7ecf\u6d4e\u5f62\u52bf\u4e0b\uff0c\u4ee5\u56fd\u5185\u5927\u5faa\u73af\u4e3a\u4e3b\u4f53\u3001\u56fd\u5185\u56fd\u9645\u53cc\u5faa\u73af\u76f8\u4e92\u4fc3\u8fdb\u7684\u65b0\u53d1\u5c55\u683c\u5c40\u662f\u7ecf\u6d4e\u793e\u4f1a\u7ed3\u6784\u6027\u8c03\u6574\u7684\u91cd\u5927\u6218\u7565\u90e8\u7f72\uff0c\u81ea\u4e3b\u521b\u65b0\u662f\u5173\u952e\u7740\u529b\u70b9\uff0c\u4ece\u81ea\u4e3b\u521b\u65b0\u5230\u81ea\u4e3b\u53ef\u63a7\uff0c\u5b9e\u73b0\u7ecf\u6d4e\u7684\u9ad8\u8d28\u91cf\u53d1\u5c55\u3002\u672c\u6587\u4ee5\u57fa\u56e0\u6d4b\u5e8f\u4eea\u4e3a\u4f8b\u9610\u8ff0\u57fa\u56e0\u884c\u4e1a\u9ad8\u7aef\u533b\u7597\u8bbe\u5907\u7684\u5e02\u573a\u683c\u5c40\u3002<\/div>\n\n
\n![\"0?wx_fmt=png\"\/](\"https:\/\/mmbiz.qlogo.cn\/mmbiz_png\/RmFicvQBAkgBSibIpjvbrWPdG3CJBYTha4LlpuARz1DEQ3os7qbXNsm3dxBTGcIZ7oHl24m0fyb9lFJ36cvJg4eA\/0?wx_fmt=png\")
<\/figure><\/div>\n\n
\u88682\uff1a\u6d4b\u5e8f\u8bbe\u5907\u4ee3\u8868\u4f01\u4e1a\uff08\u6765\u6e90\/\u57fa\u56e0\u6167\u6574\u7406\uff09<\/div>\n
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\u00a0<\/div>\n
NGS \u5e73\u53f0\u662f\u76ee\u524d\u6700\u4e3a\u5e38\u7528\u7684\u9ad8\u901a\u91cf\u6d4b\u5e8f\u5de5\u5177\uff0c\u56fd\u5185\u5916\u4e3b\u8981\u73a9\u5bb6\u7531\u534e\u5927\u667a\u9020\u3001Illumina\u548cThermo Fisher\uff08\u65d7\u4e0bIon Torrent\uff09\u30022013\u5e74\uff0c\u534e\u5927\u6536\u8d2d\u4e86\u7f8e\u56fd\u4eba\u7c7b\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u670d\u52a1\u673a\u6784 Complete Genomics\uff0c\u9010\u6b65\u638c\u63e1\u4e86\u6d4b\u5e8f\u4eea\u7814\u53d1\u80fd\u529b\u5e76\u5b8c\u6210\u6280\u672f\u8f6c\u5316\uff1b2015\u5e74\uff0c\u5728\u539f\u6709\u6280\u672f\u57fa\u7840\u4e0a\uff0c\u534e\u5927\u63a8\u51fa\u4e86\u7b2c\u4e00\u53f0\u56fd\u4ea7\u684c\u9762\u5f0f\u6d4b\u5e8f\u4eeaBGISEQ-500\uff0c\u5e76\u4e8e2016\u5e74\u6210\u7acb\u534e\u5927\u667a\u9020\u3002\u76ee\u524d\u56fd\u5185\u91cf\u4ea7\u4e34\u5e8a\u7ea7\u9ad8\u901a\u91cf\u6d4b\u5e8f\u4eea\u7684\u4f01\u4e1a\u53ea\u6709\u534e\u5927\u667a\u9020\uff0c\u5176\u4ed6\u5382\u5546\u4e3b\u8981\u548cIllumina\u3001Thermo Fisher\u4ee5\u53ca\u534e\u5927\u667a\u9020\u8054\u5408\u5f00\u53d1\u3002\u6d4b\u5e8f\u4eea\u56fd\u4ea7\u4f01\u4e1a\u7b2c\u4e8c\u68af\u961f\u5747\u5728\u7814\u53d1\u4e2d\uff0c\u5305\u62ec\u8d5b\u7eb3\u751f\u7269\u7b49\u3002\u65e9\u671f\u6295\u5165\u7814\u53d1\u7684\u534e\u56e0\u5eb7\u3001\u4e2d\u79d1\u7d2b\u946b\u7b49\u4f01\u4e1a\u5c1a\u672a\u63a8\u51fa\u6210\u719f\u3001\u91cf\u4ea7\u7684\u4ea7\u54c1\u3002<\/div>\n
\u00a0<\/div>\n
\u5728\u5355\u5206\u5b50\u6d4b\u5e8f\u9886\u57df\uff0c\u4e16\u754c\u7b2c\u4e00\u53f0\u5355\u5206\u5b50\u6d4b\u5e8f\u4eea\u662fHelicos\u57282008\u5e74\u63a8\u51fa\u7684\uff0c\u4f46\u5176\u57282012\u5e74\u7834\u4ea7\uff0c\u540e\u6765\u701a\u6d77\u57fa\u56e0\uff08\u6539\u540d\u771f\u8fc8\u751f\u7269\uff09\u8d2d\u4e70\u4e86\u5176\u77e5\u8bc6\u4ea7\u6743\u3002\u7f8e\u56fdPacific Biosciences\uff08PacBio\uff092010\u5e74\u63a8\u51fa\u7b2c\u4e00\u53f0RS\u5355\u5206\u5b50\u6d4b\u5e8f\u4eea\uff0c\u57282018\u5e74Illumina\u610f\u56fe\u6536\u8d2dPacBio\uff0c\u4f46\u6700\u7ec8\u5931\u8d25\u3002Oxford Nanopore Technologies\uff08ONT\uff09\u65d7\u4e0b\u7684\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u5e73\u53f0\uff0c\u5728\u4fbf\u643a\u5f0f\u3001\u957f\u8bfb\u957f\u6709\u4e00\u5b9a\u7684\u7ade\u4e89\u4f18\u52bf\uff0c\u4f53\u79ef\u53ef\u8fbeU\u76d8\u5927\u5c0f\uff0c\u76ee\u524d\u5728\u79d1\u7814\u9886\u57df\u9010\u6b65\u6210\u719f\uff0c\u6b63\u5728\u52a0\u5927\u4e34\u5e8a\u5e03\u5c40\u6b65\u4f10\u3002\u800c\u56fd\u5185\u4f01\u4e1a\uff0c\u5305\u62ec\u5b89\u5e8f\u6e90\u3001\u771f\u8fc8\u751f\u7269\u4e5f\u5728\u7814\u53d1\u57fa\u4e8e\u5355\u5206\u5b50\u6d4b\u5e8f\u6280\u672f\u7684\u6d4b\u5e8f\u5e73\u53f0\uff0c\u9f50\u78b3\u79d1\u6280\u5df2\u4e8e2020\u5e749\u6708\u6210\u529f\u63a8\u51fa\u81ea\u4e3b\u7814\u53d1\u7684\u7eb3\u7c73\u5b54\u57fa\u56e0\u6d4b\u5e8f\u4eeaQNome-9604\u3002<\/div>\n
\u00a0<\/div>\n
\u533b\u7597\u8bbe\u5907\u56fd\u4ea7\u5316\u7ea2\u5229\u4e0b\uff0c\u57fa\u56e0\u884c\u4e1a\u7684\u673a\u9047<\/div>\n
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\u00a0<\/div>\n
\u25a0\u00a0\u6280\u672f\u7a81\u7834\u662f\u56fd\u5185\u5916\u8bbe\u5907\u7f29\u5c0f\u5dee\u8ddd\u7684\u7740\u529b\u70b9<\/div>\n
\u5c3d\u7ba1\u56fd\u4ea7\u533b\u7597\u8bbe\u5907\u56e0\u53d1\u5c55\u5386\u53f2\u8f83\u77ed\u3001\u4ea7\u4e1a\u94fe\u5f85\u5b8c\u5584\u548c\u6280\u672f\u6c89\u6dc0\u4e0d\u591f\u5145\u5206\u7b49\u539f\u56e0\uff0c\u5bfc\u81f4\u4e0e\u8fdb\u53e3\u533b\u7597\u8bbe\u5907\u4ecd\u5b58\u5728\u4e00\u5b9a\u5dee\u8ddd\uff0c\u4f46\u76ee\u524d\u5df2\u6709\u5927\u91cf\u7814\u7a76\u53ca\u6210\u679c\u8868\u660e\u56fd\u4ea7\u8bbe\u5907\u4e0e\u8fdb\u53e3\u4ea7\u54c1\u7684\u5dee\u8ddd\u6b63\u5728\u8fc5\u901f\u7f29\u5c0f\u3002<\/div>\n
\u00a0<\/div>\n
\u4ee5NGS\u5e73\u53f0\u7684\u6d4b\u5e8f\u6027\u80fd\u4e3a\u4f8b\uff0c\u97e9\u56fd\u7684\u7814\u7a76\u56e2\u961f\u4e8e2021\u5e744\u670817\u65e5\uff0c\u5728Genes & Genomics\u6742\u5fd7\u5728\u7ebf\u53d1\u8868\u4e86\u7814\u7a76\u6587\u7ae0\uff0c\u8be5\u7814\u7a76\u5bf9\u534e\u5927\u667a\u9020MGISEQ-2000\u548cDNBSEQ-T7\u5e73\u53f0\u4e0eIllumina\u7684NovaSeq 6000\u5728\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u8fdb\u884c\u4e86\u6bd4\u8f83\u5206\u6790\uff0c\u53d1\u73b0\u4e09\u4e2a\u5e73\u53f0\u7684\u6d4b\u5e8f\u6027\u80fd\u5177\u6709\u9ad8\u5ea6\u7684\u4e00\u81f4\u6027\u3002<\/div>\n\n
\n![\"RmFicvQBAkgBSibIpjvbrWPdG3CJBYTha4YKLSFZAsuvlVYDAJRWzyRqm9aQLprhcktmPhjrhzRC83TXSsmlHHZw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgBSibIpjvbrWPdG3CJBYTha4YKLSFZAsuvlVYDAJRWzyRqm9aQLprhcktmPhjrhzRC83TXSsmlHHZw.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe1\uff1a\u97e9\u56fd\u7814\u7a76\u56e2\u961f\u5bf9Illumina\u548c\u534e\u5927\u667a\u9020\u6d4b\u5e8f\u5e73\u53f0\u8fdb\u884c\u5bf9\u6bd4\u7684\u6587\u7ae0<\/div>\n
\uff08\u6765\u6e90\/Genes\u00a0&\u00a0Genomics\uff09<\/div>\n
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\n![\"RmFicvQBAkgBSibIpjvbrWPdG3CJBYTha4ZbicZto1Me7BtMnZmGWX1fznBJ7V7j9D5oCV3ghNBeMYCjmKN4H6E6A\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgBSibIpjvbrWPdG3CJBYTha4ZbicZto1Me7BtMnZmGWX1fznBJ7V7j9D5oCV3ghNBeMYCjmKN4H6E6A.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe2\uff1a\u827e\u5168\u5916\u5728DNBSEQ-T7\u548cNovaSeq 6000\u7684\u6570\u636e\u6307\u6807<\/div>\n
\uff08\u6765\u6e90\/\u827e\u5409\u6cf0\u5eb7\uff09<\/div>\n
\u00a0<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
\u00a0<\/div>\n
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