{"id":8902,"date":"2021-06-07T06:00:54","date_gmt":"2021-06-06T22:00:54","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100019289&idx=1&sn=305a5842713290f5f63f013eba54618a&chksm=6b717eee5c06f7f866a40beef3bf4ac5e1e19b0bfdc016a730326e58044d3c2184d193b2c085#rd"},"modified":"2026-04-01T14:57:23","modified_gmt":"2026-04-01T06:57:23","slug":"1009753","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2021\/06\/07\/1009753\/","title":{"rendered":"\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5No.147"},"content":{"rendered":"
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\"RmFicvQBAkgBOZUsXRtE11OuibDRC7S2BtpdFus6j4s2cnosVfFRZhVwKVc5AEGEUp3OBQT9Kgy4KicTjpOzndzLA\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u5728\u54fa\u4e73\u52a8\u7269\u80da\u80ce\u4e2d\u4eb2\u672c\u57fa\u56e0\u7ec4\u7684\u6574\u5408\u6781\u6613\u51fa\u9519\uff08\u6765\u6e90\/Cell\uff09<\/div>\n
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2021\u5e746\u67084\u65e5\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u53d1\u5e03\u5173\u4e8e\u516c\u5f00\u5f81\u6c42\u300a\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u957f\u671f\u968f\u8bbf\u4e34\u5e8a\u7814\u7a76\u6280\u672f\u6307\u5bfc\u539f\u5219\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b\u610f\u89c1\u7684\u901a\u77e5\u3002\u901a\u77e5\u63d0\u5230\uff0c\u57fa\u56e0\u6cbb\u7597\u662f\u6307\u901a\u8fc7\u4fee\u9970\u6216\u64cd\u7eb5\u57fa\u56e0\u7684\u8868\u8fbe\u6216\u6539\u53d8\u6d3b\u7ec6\u80de\u7684\u751f\u7269\u5b66\u7279\u6027\u4ee5\u8fbe\u5230\u6cbb\u7597\u6548\u679c\uff0c\u8fd9\u4e9b\u53d8\u5316\u5728\u4f53\u5185\u957f\u671f\u5b58\u5728\uff0c\u53ef\u80fd\u589e\u52a0\u4e0d\u53ef\u9884\u6d4b\u7684\u98ce\u9669\u3002\u4e3a\u4e86\u8bc4\u4f30\u548c\u964d\u4f4e\u8fd9\u7c7b\u98ce\u9669\uff0c\u5e76\u4e86\u89e3\u6cbb\u7597\u6548\u679c\u968f\u65f6\u95f4\u5ef6\u957f\u7684\u53d8\u5316\uff0c\u6709\u5fc5\u8981\u5bf9\u53c2\u52a0\u57fa\u56e0\u6cbb\u7597\u4e34\u5e8a\u8bd5\u9a8c\u7684\u53d7\u8bd5\u8005\u5f00\u5c55\u957f\u671f\u968f\u8bbf\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.cde.org.cn\/zdyz.do?method=largePage&id=1e05db8b93bc8c49<\/div>\n
\u00a0<\/div>\n
\u2756CDE\u53d1\u5e03\u300a\u751f\u7269\u6807\u5fd7\u7269\u5728\u6297\u80bf\u7624\u836f\u7269\u4e34\u5e8a\u7814\u53d1\u4e2d\u5e94\u7528\u6280\u672f\u6307\u5bfc\u539f\u5219\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b<\/div>\n
2021\u5e746\u67082\u65e5\uff0c\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u5ba1\u8bc4\u4e2d\u5fc3\uff08CDE\uff09\u53d1\u5e03\u300a\u751f\u7269\u6807\u5fd7\u7269\u5728\u6297\u80bf\u7624\u836f\u7269\u4e34\u5e8a\u7814\u53d1\u4e2d\u5e94\u7528\u7684\u6280\u672f\u6307\u5bfc\u539f\u5219\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b\u3002\u901a\u77e5\u63d0\u5230\uff0c\u751f\u7269\u6807\u5fd7\u7269\u5728\u6297\u80bf\u7624\u836f\u7269\u7814\u53d1\u4e2d\u7684\u4ef7\u503c\u65e5\u76ca\u51f8\u663e\uff0c\u5df2\u9010\u6b65\u6210\u4e3a\u6297\u80bf\u7624\u836f\u7269\u7814\u53d1\u8fc7\u7a0b\u4e2d\u6781\u4e3a\u91cd\u8981\u7684\u4e00\u79cd\u7814\u53d1\u5de5\u5177\u3002\u76ee\u524d\u5df2\u6709\u591a\u4e2a\u57fa\u4e8e\u751f\u7269\u6807\u5fd7\u7269\u7b5b\u9009\u60a3\u8005\u4eba\u7fa4\u7684\u6297\u80bf\u7624\u836f\u7269\u83b7\u6279\u4e0a\u5e02\uff0c\u4e3a\u8fdb\u4e00\u6b65\u63d0\u9ad8\u6211\u56fd\u6297\u80bf\u7624\u65b0\u836f\u7814\u7a76\u6c34\u5e73\uff0c\u5408\u7406\u5e94\u7528\u751f\u7269\u6807\u5fd7\u7269\u6307\u5bfc\u6297\u80bf\u7624\u836f\u7269\u7684\u4e34\u5e8a\u7814\u53d1\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.cde.org.cn\/news.do?method=largeInfo&id=f9991ca91cf05078<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u6211\u56fd\u63d0\u51fa\u5b9e\u65bd\u201c\u4e09\u5b69\u201d\u751f\u80b2\u653f\u7b56<\/div>\n
2021\u5e745\u670831\u65e5\uff0c\u4e2d\u5171\u4e2d\u592e\u653f\u6cbb\u5c40\u53ec\u5f00\u4f1a\u8bae\uff0c\u542c\u53d6\u201c\u5341\u56db\u4e94\u201d\u65f6\u671f\u79ef\u6781\u5e94\u5bf9\u4eba\u53e3\u8001\u9f84\u5316\u91cd\u5927\u653f\u7b56\u4e3e\u63aa\u6c47\u62a5\uff0c\u5ba1\u8bae\u300a\u5173\u4e8e\u4f18\u5316\u751f\u80b2\u653f\u7b56\u4fc3\u8fdb\u4eba\u53e3\u957f\u671f\u5747\u8861\u53d1\u5c55\u7684\u51b3\u5b9a\u300b\uff0c\u63d0\u51fa\u8fdb\u4e00\u6b65\u4f18\u5316\u751f\u80b2\u653f\u7b56\uff0c\u5b9e\u65bd\u4e00\u5bf9\u592b\u59bb\u53ef\u4ee5\u751f\u80b2\u4e09\u4e2a\u5b50\u5973\u653f\u7b56\u53ca\u914d\u5957\u652f\u6301\u63aa\u65bd\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.gov.cn\/xinwen\/2021-06\/01\/content_5614518.htm<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0FDA\u52a0\u901f\u6279\u51c6\u9996\u4e2aKRAS\u6291\u5236\u5242<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
\u2756\u00a0NMPA\u53d1\u5e03\u836f\u54c1\u68c0\u67e5\u65b0\u89c4\uff0c\u539fGMP\u8ba4\u8bc1\u529e\u6cd5\u5e9f\u9664<\/div>\n
2021\u5e745\u670828\u65e5\uff0c\u56fd\u5bb6\u836f\u76d1\u5c40\u53d1\u5e03\u56fd\u5bb6\u836f\u76d1\u5c40\u5173\u4e8e\u5370\u53d1\u300a\u836f\u54c1\u68c0\u67e5\u7ba1\u7406\u529e\u6cd5\uff08\u8bd5\u884c\uff09\u300b\u7684\u901a\u77e5\u3002\u539f\u56fd\u5bb6\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c402003\u5e744\u670824\u65e5\u53d1\u5e03\u7684\u300a\u836f\u54c1\u7ecf\u8425\u8d28\u91cf\u7ba1\u7406\u89c4\u8303\u8ba4\u8bc1\u7ba1\u7406\u529e\u6cd5\u300b\u548c2011\u5e748\u67082\u65e5\u53d1\u5e03\u7684\u300a\u836f\u54c1\u751f\u4ea7\u8d28\u91cf\u7ba1\u7406\u89c4\u8303\u8ba4\u8bc1\u7ba1\u7406\u529e\u6cd5\u300b\u540c\u65f6\u5e9f\u6b62\u3002<\/div>\n
\u524d\u6cbf\u6280\u672f<\/div>\n
\u2756\u00a0\u53d1\u73b0\u975e\u6d32\u88d4\u7f8e\u56fd\u4eba\u548c\u6b27\u6d32\u88d4\u7f8e\u56fd\u4eba\u7684\u524d\u5217\u817a\u80bf\u7624\u57fa\u56e0\u7ec4\u8c31\u4e0d\u540c<\/div>\n
\u5f53\u5730\u65f6\u95f42021\u5e746\u67083\u65e5\uff0c\u897f\u5948\u5c71\u4f0a\u574e\u533b\u5b66\u9662\u9886\u5bfc\u7684\u56e2\u961f\u5728Communications Biology\u671f\u520a\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u5373\u5bf9\u4e00\u5343\u591a\u540d\u7537\u6027\u7684\u80bf\u7624\u8fdb\u884c\u4e86\u56de\u987e\u6027\u5206\u6790\uff0c\u53d1\u73b0\u975e\u6d32\u88d4\u7f8e\u56fd\u4eba\u548c\u6b27\u6d32\u88d4\u7f8e\u56fd\u4eba\u7684\u524d\u5217\u817a\u80bf\u7624\u57fa\u56e0\u7ec4\u8c31\u4e0d\u540c\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u975e\u88d4\u7f8e\u56fd\u7537\u6027\u7684\u80bf\u7624\u60a3\u8005\u66f4\u6709\u53ef\u80fd\u5177\u6709\u66f4\u9ad8\u7684\u514d\u75ab\u53cd\u5e94\u3001\u7f3a\u6c27\u548c\u7ec6\u80de\u51cb\u4ea1\u76f8\u5173\u57fa\u56e0\u7684\u8868\u8fbe\u4ee5\u53ca\u9519\u914d\u4fee\u590d\u57fa\u56e0\u7684\u8868\u8fbe\u964d\u4f4e\u3002\u00a0\u7279\u522b\u662f\uff0cIL33\u3001IFNG\u3001CCL4\u3001CD3 \u548c ICOSLG \u7b49\u708e\u75c7\u57fa\u56e0\u5728\u975e\u88d4\u7f8e\u56fd\u60a3\u8005\u6837\u672c\u4e2d\u4e0a\u8c03\uff0c\u800c MSH2 \u548c MSH6 \u7b49 DNA \u9519\u914d\u4fee\u590d\u57fa\u56e0\u4e0b\u8c03\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1038\/s42003-021-02140-y<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u91cd\u65b0\u8bbe\u8ba1\u5927\u80a0\u6746\u83cc\u7684\u5bc6\u7801\u5b50\uff0c\u83b7\u5f97\u5236\u836f\u65b0\u601d\u8def<\/div>\n
\u5f53\u5730\u65f6\u95f42021\u5e746\u67083\u65e5\uff0cSciense\u671f\u520a\u53d1\u8868\u6587\u7ae0\u79f0\uff0c\u79d1\u5b66\u5bb6\u4f7f\u80fd\u591f\u4e00\u6b21\u5c06\u4e09\u79cd\u975e\u5929\u7136\u6c28\u57fa\u9178\u6dfb\u52a0\u5230\u5355\u4e2a\u86cb\u767d\u8d28\u4e2d\u5e76\u4fdd\u7559\u591a\u4e2a\u526f\u672c\u3002\u800c\u91cd\u65b0\u8bbe\u8ba1\u5927\u80a0\u6746\u83cc\u7684\u7ec8\u6b62\u5bc6\u7801\u5b50\u53ef\u80fd\u4f1a\u7834\u574f\u75c5\u6bd2\u7684\u590d\u5236\u80fd\u529b\u3002\u8fd9\u662f\u56e0\u4e3a\u75c5\u6bd2\u4f9d\u8d56\u5927\u80a0\u6746\u83cc\u7684\u5929\u7136\u5bc6\u7801\u5b50\u6765\u5236\u9020\u529f\u80fd\u6027\u86cb\u767d\u8d28\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1126\/science.abj8197<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0II\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u53d7\u76ca\u4e8e\u5e72\u7ec6\u80de\u79fb\u690d<\/div>\n
\u5f53\u5730\u65f6\u95f42021\u5e746\u67083\u65e5\uff0c\u5728\u8d8a\u5357\u6cb3\u5185 Vinmec \u5e72\u7ec6\u80de\u548c\u57fa\u56e0\u6280\u672f\u7814\u7a76\u6240\u7684\u4e00\u9879\u968f\u673a\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u8c03\u67e5\u4e86\u5411 II \u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u79fb\u690d\u9aa8\u9ad3\u57fa\u8d28\u5e72\u7ec6\u80de\u7684\u5b89\u5168\u6027\u548c\u6f5c\u5728\u6cbb\u7597\u4ef7\u503c\u3002\u5728\u6bcf\u79cd\u60c5\u51b5\u4e0b\uff0c\u7ec6\u80de\u90fd\u662f\u81ea\u4f53\u7684\u6216\u8005\u53d6\u81ea\u60a3\u8005\u81ea\u5df1\u7684\u8eab\u4f53\u3002\u7ed3\u679c\u8868\u91cc\uff0c\u672a\u8d85\u91cd\u4e14\u60a3\u75c5\u65f6\u95f4\u4e0d\u5230\u5341\u5e74\u7684 II \u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u53ef\u4ee5\u4ece\u81ea\u4f53\u9aa8\u9ad3\u79fb\u690d\u7684\u57fa\u8d28\u5e72\u7ec6\u80de\u4e2d\u83b7\u76ca\u3002\u76f8\u5173\u8bba\u6587\u53d1\u8868\u5728\u53d1\u8868\u5728 Stem Cells Translational Medicine \u4e0a\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1002\/sctm.20-0506<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u6e05\u534e\u5927\u5b66\u6c6a\u5c0f\u6211\u56e2\u961f\u53d1\u8868\u6e38\u79bbDNA\u6d4b\u5e8f\u6570\u636e\u5206\u6790\u6d41\u7a0b\u8f6f\u4ef6\u5305<\/div>\n
2021\u5e745\u670827\u65e5\uff0c\u6e05\u534e\u5927\u5b66\u7684\u6c6a\u5c0f\u6211\u6559\u6388\u56e2\u961f\u548c\u6e05\u534e\u2013\u798f\u5dde\u6570\u636e\u6280\u672f\u7814\u7a76\u9662\u5408\u4f5c\uff0c\u5728Bioinformatics\u4e0a\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u5373\u5f00\u53d1\u4e86\u4e00\u5957\u9488\u5bf9cfDNA\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u548c\u5168\u57fa\u56e0\u7ec4\u7532\u57fa\u5316\u6d4b\u5e8f\u6570\u636e\u7684\u7cfb\u7edf\u5206\u6790\u8f6f\u4ef6\u5305\u201ccfDNApipe\u201d\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1093\/bioinformatics\/btab413<\/div>\n
\u00a0<\/div>\n
\u4ea7\u54c1\u5e94\u7528<\/div>\n
\u2756 \u7f8e\u56fd\u4f01\u4e1aGrail\u7684\u764c\u75c7\u65e9\u8bca\u68c0\u6d4b\u53ef\u5728\u7f8e\u51ed\u5904\u65b9\u8d2d\u4e70<\/div>\n
\u5f53\u5730\u65f6\u95f42021\u5e746\u67084\u65e5\uff0c\u6839\u636e\u77e5\u540d\u7684\u764c\u75c7\u65e9\u8bca\u4f01\u4e1aGrail\u5b98\u7f51\u6d88\u606f\uff0cGrail\u57282021 \u5e74 ASCO \u5e74\u4f1a\u4e0a\u516c\u5e03\u7684\u7ed3\u679c\u652f\u6301 Galleri \u5728\u4e34\u5e8a\u73af\u5883\u4e2d\u7684\u8868\u73b0\u3002Galleri \u73b0\u5728\u7f8e\u56fd\u53ef\u4ee5\u901a\u8fc7\u5904\u65b9\u5728\u7f8e\u56fd\u83b7\u5f97\u3002<\/div>\n
Grail\u7684\u4ea7\u54c1\u8868\u73b0\u5982\u4f55\uff0c\u57fa\u56e0\u6167\u6574\u7406\u5982\u4e0b\uff1a<\/div>\n
1\uff09\u5728\u4e2d\u671f\u5206\u6790\u4e2d\uff0c\u65e9\u671f\u7248\u672c\u7684 Galleri \u51c6\u786e\u68c0\u6d4b\u4e86 13 \u79cd\u7c7b\u578b\u7684 29 \u79cd\u764c\u75c7\uff1a\u4e73\u817a\u764c\u3001\u7ed3\u80a0\u764c\u6216\u76f4\u80a0\u764c\u3001\u5934\u9888\u764c\u3001\u809d\u80c6\u7ba1\u764c\u3001\u80ba\u764c\u3001\u6dcb\u5df4\u767d\u8840\u75c5\u3001\u6dcb\u5df4\u7624\u3001\u5375\u5de2\u764c\u3001\u80f0\u817a\u764c\u3001\u6d46\u7ec6\u80de\u80bf\u7624\u3001\u524d\u5217\u817a\u764c\u3001\u5c0f\u80a0\u548c Waldenstrom \u5de8\u7403\u86cb\u767d\u8840\u75c7\u3002\u5728\u68c0\u6d4b\u5230\u7684\u65b0\u764c\u75c7\u4e2d\uff0c\u8fd1 40% (9\/23) \u662f\u5c40\u90e8\u7684\uff08I-II \u671f\uff09\uff0c\u8d85\u8fc7\u4e00\u534a\uff0813\/23\uff09\u662f\u5728\u8fdc\u5904\u8f6c\u79fb\uff08I-III \u671f\uff09\u4e4b\u524d\u68c0\u6d4b\u5230\u7684\u3002PATHFINDER \u53c2\u4e0e\u8005\u5c06\u7ee7\u7eed\u88ab\u8ddf\u8e2a 12 \u4e2a\u6708\uff0c\u6700\u7ec8\u7ed3\u679c\u9884\u8ba1\u5c06\u5728 2022 \u5e74\u4e0a\u534a\u5e74\u516c\u5e03<\/div>\n
2\uff09\u4e2d\u671f PATHFINDER \u7684\u9633\u6027\u9884\u6d4b\u503c (PPV)\u4e3a 44.6%\uff0895% CI\uff1a33.2-56.7%\uff09\uff0c\u8fd9\u4e0e GRAIL \u75c5\u4f8b\u5bf9\u7167\u7684\u7684\u5faa\u73af\u65e0\u7ec6\u80de\u57fa\u56e0\u7ec4\u56fe\u8c31 (CCGA) \u7814\u7a76\u7ed3\u679c\u4e00\u81f4\u3002<\/div>\n
3\uff09\u5bf9\u4e8e\u5df2\u77e5\u764c\u75c7\u60a3\u8005\uff0cGalleri \u7684\u7b2c\u4e00\u4e2a\u6216\u7b2c\u4e8c\u4e2a\u764c\u75c7\u4fe1\u53f7\u6765\u6e90\u9884\u6d4b\u51c6\u786e\u7387\u4e3a 96.3%\uff0895% CI\uff1a81.7-99.8%\uff09\uff0c\u764c\u75c7\u8bca\u65ad\u7684\u4e2d\u4f4d\u89c2\u5bdf\u65f6\u95f4\u4e3a 50 \u5929\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/grail.com\/press-releases\/grail-presents-interventional-pathfinder-study-data-at-2021-asco-annual-meeting-and-introduces-galleri-a-groundbreaking-multi-cancer-early-detection-blood-test\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u534e\u5927\u57fa\u56e0\u4e2d\u6807\u76ca\u9633\u5e02\u5065\u5eb7\u6c11\u751f\u670d\u52a1\u9879\u76ee\uff0c\u603b\u91d1\u989d\u4e3a1.14\u4ebf\u5143<\/div>\n
2021\u5e746\u67086\u65e5\uff0c\u534e\u5927\u57fa\u56e0(300676.SZ)\u53d1\u5e03\u516c\u544a\uff0c\u516c\u53f8\u63a7\u80a1\u5b50\u516c\u53f8\u6df1\u5733\u534e\u5927\u533b\u5b66\u68c0\u9a8c\u5b9e\u9a8c\u5ba4\u4e2d\u6807\u76ca\u9633\u5e02\u5065\u5eb7\u6c11\u751f\u670d\u52a1\u9879\u76ee\uff0c\u4e2d\u6807\u91d1\u989d\u4e3a1.14\u4ebf\u5143\u4eba\u6c11\u5e01\u3002\u670d\u52a1\u5185\u5bb9\u5305\u542b\u65e0\u521b\u4ea7\u524d\u57fa\u56e0\u68c0\u6d4b\u3001\u9057\u4f20\u6027\u8033\u804b\u57fa\u56e0\u68c0\u6d4b\u3001\u5730\u4e2d\u6d77\u8d2b\u8840\u57fa\u56e0\u68c0\u6d4b\u3001\u65b0\u751f\u513f\u9057\u4f20\u4ee3\u8c22\u75c5\u68c0\u6d4b\u3001\u6269\u5c55\u6027\u5355\u57fa\u56e0\u9057\u4f20\u75c5\u643a\u5e26\u8005\u7b5b\u67e5\u548c\u65b0\u751f\u513f\u5168\u57fa\u56e0\u7ec4\u68c0\u6d4b\u3002<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u53d1\u5c55<\/div>\n
\u2756\u00a023andme \u8ba1\u52126\u670817\u65e5\u5728\u7eb3\u65af\u8fbe\u514b\u4e0a\u5e02<\/div>\n
2021\u5e746\u67082\u65e5\uff0c\u8ba1\u5212\u5e76\u8d2d23andme\u7684SPAC\u516c\u53f8VGAC\u53d1\u51fa\u516c\u544a\uff0c\u63d0\u9192\u80a1\u4e1c\u5bf9\u6536\u8d2d23andme\u5e76\u7ec4\u5efa\u65b0\u516c\u53f8New 23andme\u7684\u63d0\u8bae\u8fdb\u884c\u6295\u7968\uff0c\u5982\u679c\u63d0\u8bae\u901a\u8fc7\uff0c\u6536\u8d2d\u5c06\u57286\u670816\u65e5\u5b8c\u6210\uff0c\u65b0\u516c\u53f8\u7684\u80a1\u7968\u5c06\u4e8e6\u670817\u65e5\u5728\u7eb3\u65af\u8fbe\u514b\u6302\u724c\u4ea4\u6613\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>(Proxy Statement\u6587\u4ef6\uff09<\/div>\n
https:\/\/www.proxydocs.com\/branding\/966273\/2021\/ps\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u5355\u7ec6\u80de\u4f01\u4e1a\u5fb7\u8fd0\u5eb7\u745e\u5ba3\u5e03\u5b8c\u6210\u6536\u8d2d\u5fae\u8457\u751f\u7269<\/div>\n
2021\u5e745\u670825\u65e5\uff0c\u82cf\u5dde\u5fb7\u8fd0\u5eb7\u745e\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\u6b63\u5f0f\u5ba3\u5e03\u5b8c\u6210\u4e86\u5bf9\u676d\u5dde\u5fae\u8457\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\uff08\u7684\u6536\u8d2d\u6574\u5408\u4e0e\u80a1\u6743\u53d8\u66f4\u3002\u5fae\u8457\u751f\u7269\u81f4\u529b\u4e8e\u5f00\u53d1\u5fae\u7403\u7f16\u7801\u6280\u672f\u4e0e\u5355\u7ec6\u80de\u6d4b\u5e8f\u5e73\u53f0Paired-seq\u3002<\/div>\n\n
\n
\"0?wx_fmt=jpeg\"\/<\/figure><\/div>\n\n
\u7531\u57fa\u56e0\u6167\u53d1\u8d77\uff0c\u6a0a\u5609\u9662\u58eb\u4f5c\u5e8f\uff0c\u591a\u5bb6\u77e5\u540d\u673a\u6784\u53c2\u4e0e\u7684<\/div>\n
\u300a2021\u80bf\u7624\u57fa\u56e0\u53ca\u5206\u5b50\u68c0\u6d4b\u84dd\u76ae\u4e66\u300b<\/div>\n
\u5373\u5c06\u57289\u6708\u53d1\u5e03<\/div>\n
\u6b22\u8fce\u4e34\u5e8a\u4e13\u5bb6\u53ca\u4f01\u4e1a\u201c\u8054\u5408\u53d1\u5e03\u201d<\/div>\n
\u8054\u7edc\u90ae\u7bb1 info@genonet.cn<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4e2a\u4eba\u57fa\u56e0\u7ec4\u4f01\u4e1aHelix\u5b8c\u62105000\u4e07\u7f8e\u5143C\u8f6e\u878d\u8d44<\/div>\n
2021\u5e746\u67084\u65e5\uff0c\u7f8e\u56fd\u57fa\u56e0\u7ec4\u516c\u53f8Helix\u5ba3\u5e03\u5b8c\u62105000\u4e07\u7f8e\u5143\u7684C\u8f6e\u878d\u8d44\uff0c\u7531\u73b0\u6709\u6295\u8d44\u4ebaWarburg Pincus\u3001DFJ Growth\u3001Kleiner Perkins Caufield Byers \u3001\u6885\u5965\u8bca\u6240\u548c\u6de1\u9a6c\u9521\u9886\u6295\u3002\u7531\u4e2a\u4eba\u57fa\u56e0\u7ec4\u8d77\u5bb6\u7684Helix\u8fd9\u8f6e\u878d\u8d44\u4e3b\u8981\u7528\u4e8e\u4e34\u5e8a\u7fa4\u4f53\u57fa\u56e0\u7ec4\u548c\u65b0\u51a0\u68c0\u6d4b\uff0c\u6838\u5fc3\u4ea7\u54c1\u662fExome+\u00ae \uff0c\u8986\u76d6\u5927\u7ea6 20,000 \u4e2a\u86cb\u767d\u8d28\u7f16\u7801\u57fa\u56e0\u548c 300,000 \u4e2a\u4fe1\u606f\u4e30\u5bcc\u7684\u975e\u7f16\u7801\u533a\u57df\u6d4b\u5e8f\u30022021\u5e741\u6708\uff0cHelix\u5b9e\u9a8c\u5ba4\u5e73\u53f0\u83b7\u5f97FDA\u9996\u4e2a\u4e5f\u662f\u552f\u4e00\u4e00\u4e2a\u5168\u5916\u663e\u5b50\u7ec4\u6d4b\u5e8f\u5e73\u53f0\u6388\u6743\u3002\u6b64\u5916\uff0cHelix \u7684\u8054\u5408\u521b\u59cb\u4ebaJames Lu\u51fa\u4efbCEO\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u5408\u6210\u751f\u7269\u5b66\u4f01\u4e1a\u8fea\u8d62\u751f\u7269\u5b8c\u6210\u8fd1\u4ebf\u5143A\u8f6e\u878d\u8d44<\/div>\n
2021\u5e746\u67085\u65e5\uff0c\u5408\u6210\u751f\u7269\u5b66\u4f01\u4e1a\u8fea\u8d62\u751f\u7269\u5ba3\u5e03\u5b8c\u6210\u8fd1\u4ebf\u5143A\u8f6e\u878d\u8d44\uff0c\u7531\u548c\u7389\u8d44\u672c\u3001\u5de2\u751f\u8d44\u672c\u7b49\u5171\u540c\u6295\u8d44\uff0c\u8001\u80a1\u4e1c\u706b\u5c71\u77f3\u8d44\u672c\u7ee7\u7eed\u8ddf\u8fdb\u3002\u636e\u4e86\u89e3\uff0c\u672c\u8f6e\u878d\u8d44\u5c06\u4e3b\u8981\u7528\u4e8e\u8fdb\u4e00\u6b65\u592f\u5b9e\u516c\u53f8\u7684\u65b0\u4e00\u4ee3\u8d85\u9ad8\u901a\u91cfDNA\u5408\u6210\u6280\u672f\uff0c\u5c06\u76ee\u524d\u5df2\u7ecf\u5546\u4e1a\u5316\u7684DYHOW\u65b0\u4e00\u4ee3DNA\u5408\u6210\u5e73\u53f0\u7684\u5408\u6210\u901a\u91cf\u63d0\u5347\u81f3\u767e\u4e07\u7ea7\uff0c\u540c\u65f6\u5b8c\u5584\u516c\u53f8\u4ea7\u54c1\u7ba1\u7ebf\u5e03\u5c40\uff0c\u6269\u5efa\u65b0\u7684\u7814\u53d1\u751f\u4ea7\u57fa\u5730\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u611f\u67d3\u68c0\u6d4b\u4f01\u4e1a\u91d1\u5319\u533b\u5b66\u5ba3\u5e03C+\u8f6e\u878d\u8d44\u518d\u6dfb\u4e24\u4f4d\u6218\u7565\u6295\u8d44\u8005<\/div>\n
2021\u5e746\u67081\u65e5\uff0c\u636e\u52a8\u8109\u7f51\u62a5\u9053\uff0c\u91d1\u5319\u533b\u5b66\u5ba3\u5e03C+\u8f6e\u878d\u8d44\u518d\u6dfb\u4e24\u4f4d\u6218\u7565\u6295\u8d44\u8005\uff0c\u5206\u522b\u662f\u6cf0\u5eb7\u6295\u8d44\u548c\u5143\u79be\u539f\u70b9\uff0c\u4e0d\u4e45\u524d\u91d1\u5319\u533b\u5b66\u521a\u521a\u5ba3\u5e03\u83b7\u5f97CPE\u6e90\u5cf0\u6570\u4ebf\u5143\u6218\u7565\u6295\u8d44\u3002\u636e\u4e86\u89e3\uff0c\u672c\u8f6e\u878d\u8d44\u540e\uff0c\u91d1\u5319\u533b\u5b66\u5c06\u66f4\u597d\u7684\u501f\u52a9CPE\u6e90\u5cf0\u3001\u6cf0\u5eb7\u96c6\u56e2\u548c\u5143\u79be\u539f\u70b9\u5728\u533b\u7597\u9886\u57df\u7684\u4f18\u8d28\u8d44\u6e90\u548c\u4e13\u4e1a\u7684\u6295\u8d44\u5e03\u5c40\uff0c\u52a0\u901f\u611f\u67d3\u75c5\u57fa\u56e0\u68c0\u6d4b\u7c7b\u4ea7\u54c1\u7684\u7814\u53d1\u548c\u63a8\u5e7f\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u5148\u58f0\u8bca\u65ad\u5b8c\u6210\u8fd1\u516d\u4ebf\u5143B\u8f6e\u878d\u8d44<\/div>\n
2021\u5e746\u67084\u65e5\uff0c\u5148\u58f0\u8bca\u65ad\u5b98\u65b9\u5ba3\u5e03\u4eca\u65e5\u5b8c\u6210\u8fd1\u516d\u4ebf\u4eba\u6c11\u5e01\u7684B\u8f6e\u878d\u8d44\u3002\u672c\u8f6e\u878d\u8d44\u7531\u4e2d\u4fe1\u8bc1\u5238\u6295\u8d44\u53ca\u4e2d\u4fe1\u533b\u7597\u57fa\u91d1\u9886\u6295\uff0c\u76c8\u79d1\u8d44\u672c\u3001\u539a\u65b0\u5065\u6295\u3001\u91d1\u6d66\u56fd\u8c03\u3001\u521b\u745e\u6295\u8d44\u3001\u4ec1\u749e\u533b\u7597\u57fa\u91d1\u3001\u5b8f\u8bda\u6295\u8d44\u3001\u91d1\u96e8\u8302\u7269\u548c\u5357\u4eac\u521b\u65b0\u6295\u8ddf\u6295\uff0c\u8001\u80a1\u4e1c\u5929\u6c47\u8d44\u672c\u7ee7\u7eed\u52a0\u6301\u3002<\/div>\n
\u00a0<\/div>\n
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