{"id":8859,"date":"2021-09-22T23:03:11","date_gmt":"2021-09-22T15:03:11","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&mid=100020715&idx=1&sn=1b7feb198f0efbd941ccea0f72814912&chksm=6b71635c5c06ea4aa69ae9ecffc8a64a28db4b893a7a81068e88b1a0cc5daa94c8ce9b1e0c71#rd"},"modified":"2026-04-07T17:18:01","modified_gmt":"2026-04-07T09:18:01","slug":"975049","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2021\/09\/22\/975049\/","title":{"rendered":"\u9ad8\u9f84\u60a3\u8005\u5371\u91cd\u75c7\u98ce\u9669\u9ad83\u500d\uff01\u534e\u5927\u667a\u9020\u6d4b\u5e8f\u5e73\u53f0\u52a9\u529b\u63ed\u793a\u5fb7\u5c14\u5854\u53d8\u5f02\u682a\u5b8c\u6574\u4f20\u64ad\u94fe\u53ca\u4e34\u5e8a\u7279\u5f81\u7814\u7a76"},"content":{"rendered":"

<\/p>\n

\u8fd1\u65e5\uff0c\u798f\u5efa\u7701\u8386\u7530\u5e02\u548c\u53a6\u95e8\u5e02\u76f8\u7ee7\u51fa\u73b0\u672c\u571f\u65b0\u51a0\u80ba\u708e\u75c5\u4f8b\u8086\u8650\uff0c\u6b64\u6b21\u75ab\u60c5\u521d\u6b65\u5224\u5b9a\u4e3a\u7531\u5fb7\u5c14\u5854\u53d8\u5f02\u682a\uff08Delta VOC, variant of concern\uff09\u5f15\u8d77\uff0c\u4e14\u5df2\u8fc5\u901f\u6210\u4e3a\u76ee\u524d\u76db\u884c\u7684\u4f18\u52bf\u6bd2\u682a\u3002\u56fd\u5185\u5916\u536b\u751f\u7cfb\u7edf\u6570\u636e\u5747\u521d\u6b65\u663e\u793aDelta VOC\u4f20\u64ad\u529b\u5f3a\uff0c\u4f46\u56fd\u5185\u5916\u5c1a\u672a\u5145\u5206\u8ba4\u8bc6Delta\u53d8\u5f02\u682a\u7684\u4f20\u64ad\u94fe\u3001\u75c5\u6bd2\u52a8\u529b\u5b66\u548c\u4e34\u5e8a\u7279\u5f81\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u5e7f\u5dde\u56e2\u961f\u9996\u53d1Delta\u53d8\u5f02\u682a\u5b8c\u6574\u4f20\u64ad\u94fe<\/div>\n
\u4eca\u5e74\u4e94\u6708\u5e95\uff0c\u7531Delta\u53d8\u5f02\u682a\u5f15\u8d77\u7684\u65b0\u4e00\u8f6e\u75ab\u60c5\u4ee5\u5e7f\u5dde\u4e3a\u4e2d\u5fc3\u5f00\u59cb\u7206\u53d1\u3002\u5e7f\u5dde\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u5e02\u516b\u533b\u9662\u3001\u5e7f\u5dde\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u7b2c\u4e00\u533b\u9662\u7b49\u9488\u5bf9\u6b64\u6b21\u75ab\u60c5\uff0c\u7ed3\u5408\u6d41\u884c\u75c5\u5b66\u548c\u75c5\u6bd2\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u6280\u672f\uff0c\u9996\u6b21\u8be6\u5c3d\u5730\u63cf\u7ed8\u51faDelta\u53d8\u5f02\u682a\u7684\u5b8c\u6574\u4f20\u64ad\u94fe\uff0c\u5e76\u5206\u6790\u4e86Delta\u53d8\u5f02\u682a\u7684\u75c5\u6bd2\u52a8\u529b\u5b66\u7279\u70b9\u548c\u4e34\u5e8a\u7279\u5f81\u3002\u7ed3\u679c\u663e\u793a\uff1a\u4e0e\u91ce\u751f\u682a\u961f\u5217\u76f8\u6bd4\uff0cDelta VOC\u4f20\u64ad\u66f4\u5feb\uff0c\u6f5c\u4f0f\u671f\u66f4\u77ed\uff0c\u75c5\u6bd2\u8f7d\u91cf\u66f4\u9ad8\u53ca\u75c5\u6bd2\u6e05\u9664\u65f6\u95f4\u66f4\u957f\uff0c\u9ad8\u9f84\u60a3\u8005\u611f\u67d3Delta VOC\u66f4\u5bb9\u6613\u5c55\u4e3a\u5371\u91cd\u75c7\u3002<\/div>\n
\u00a0<\/div>\n
\u503c\u5f97\u5173\u6ce8\u7684\u662f\uff0c\u672c\u7814\u7a76\u4e2d\u7528\u4e8e\u6784\u5efa\u7cfb\u7edf\u53d1\u80b2\u6811\u7684\u75c5\u6bd2\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\uff0c\u4f7f\u7528\u4e86\u534e\u5927\u667a\u9020\u7684MGISEQ-2000\u9ad8\u901a\u91cf\u6d4b\u5e8f\u4eea\u548cATOPlex SARS-CoV-2\u5168\u57fa\u56e0\u7ec4\u6269\u589epanel\u3002<\/div>\n
\u672c\u6b21\u7814\u7a76\u6210\u679c\u540d\u4e3a\u201cTransmission, viral kinetics and clinical characteristics of the emergent SARS-CoV-2 Delta VOC in Guangzhou, China\u201d\uff0c\u5df2\u4e8e9\u670812\u65e5\u53d1\u8868\u5728\u56fd\u9645\u6743\u5a01\u533b\u5b66\u671f\u520a\u300a\u67f3\u53f6\u5200\u300b\uff08The Lancet\uff09\u5b50\u520aEClinicalMedicine\u4e0a\u3002<\/div>\n
\u00a0<\/div>\n
\u6750\u6599\u4e0e\u65b9\u6cd5<\/div>\n
\u672c\u6b21\u7814\u7a76\u7684\u7814\u7a76\u5bf9\u8c61\u4e3a2021\u5e745\u670821\u65e5\u81f36\u670818\u65e5\u5728\u5e7f\u5dde\u786e\u8bca\u7684159\u4f8bDelta\u53d8\u5f02\u682a\u75c5\u4f8b\uff0c\u5e76\u4e0e2020 \u5e741\u6708\u81f32\u6708\u611f\u67d3\u65b0\u51a0\u91ce\u751f\u578bSARS-CoV-2\u7684260\u4f8b\u75c5\u4f8b\u8fdb\u884c\u4e86\u5bf9\u6bd4\u3002\u6b64\u5916\uff0c\u8fd8\u6536\u96c6\u6574\u7406\u4e86\u6240\u6709\u786e\u8bca\u60a3\u8005\u7684\u786e\u8bca\u75c5\u4f8b\u63a5\u89e6\u53f2\u53ca\u65c5\u5c45\u53f2\u7b49\u6d41\u884c\u75c5\u5b66\u6570\u636e\u3002\u7ecf\u8fc7\u6d41\u884c\u75c5\u5b66\u8c03\u67e5\u548c\u7cfb\u7edf\u53d1\u80b2\u6811\u5206\u6790\uff0c\u8be5\u7814\u7a76\u63ed\u793a\u4e86Delta\u53d8\u5f02\u682a\u7684\u5b8c\u6574\u4f20\u64ad\u94fe\u3002<\/div>\n\n
\n
\"RmFicvQBAkgB1DMpqWObzasiczMn3Awdr45dEXPa4ROxU0DjQVhicBgyoe4sGYCpf9jdXOib5fzyYWFfPHVDS3KNCQ\"\/<\/figure><\/div>\n\n

\uff08\u5e7f\u5dde\u533b\u79d1\u5927\u5b66\u9644\u5c5e\u5e02\u516b\u533b\u9662\u7814\u7a76\u56e2\u961f\u6b63\u5728\u4f7f\u7528\u534e\u5927\u667a\u9020MGISEQ-2000\u6d4b\u5e8f\u5e73\u53f0\uff09<\/p>\n

\u7ed3\u8bba<\/div>\n
1.\u4f20\u64ad\u94fe\u2014\u2014\u5171\u540c\u7528\u9910\u548c\u5bb6\u5ead\u63a5\u89e6\u7684\u4f20\u64ad\u6bd4\u4f8b\u6700\u9ad8<\/div>\n
Delta\u53d8\u5f02\u682a\u4e3b\u8981\u901a\u8fc7\u76f4\u63a5\u548c\u95f4\u63a5\u7684\u8fd1\u8ddd\u79bb\u63a5\u89e6\u4f20\u64ad\uff0c\u5176\u4e2d\u5171\u540c\u7528\u9910\u5360\u6bd4\u6700\u9ad8\uff0830.8%\uff09\uff0c\u5176\u6b21\u5206\u522b\u662f\u5bb6\u5ead\u63a5\u89e6(29.6%)\u3001\u793e\u533a\u4f20\u64ad(18.2%)\uff0c\u4ee5\u53ca\u5305\u62ec\u5de5\u4f5c\u548c\u793e\u4ea4\u63a5\u89e6\u5728\u5185\u7684\u5176\u4ed6\u4f20\u64ad\u9014\u5f84\uff0819.87%\uff09\u3002Delta\u53d8\u5f02\u682a\u4e34\u5e8a\u7279\u5f81\u8bf8\u591a\uff0c\u5165\u9662\u4e09\u5929\u5185\u6700\u5e38\u89c1\u7684\u75c7\u72b6\u662f\u54b3\u55fd\uff0865%\uff09\uff0c\u5176\u6b21\u662f\u53d1\u70e7\uff0863%\uff09\u548c\u54b3\u75f0\uff0853%\uff09\u3002\u8179\u6cfb (5%) \u548c\u5455\u5410 (4%) \u7b49\u80c3\u80a0\u9053\u75c7\u72b6\u5e76\u4e0d\u5e38\u89c1\u3002<\/div>\n\n
\n
\"RmFicvQBAkgB1DMpqWObzasiczMn3Awdr4xasz9ibSOd1m0VurNSWVFrtyQRv2TTkHkibH4RnlbdMQ88XsibaSRlMrA\"\/<\/figure><\/div>\n\n

\uff08\u5e7f\u5ddeDelta\u53d8\u5f02\u682a\u7684\u6d41\u884c\u75c5\u5b66\u4f20\u64ad\u7f51\u7edc\uff09<\/p>\n

2.\u6f5c\u4f0f\u671f\u66f4\u77ed\uff0c\u4f20\u64ad\u901f\u5ea6\u5feb<\/div>\n
\u7814\u7a76\u6570\u636e\u8868\u660e\uff0cDelta\u53d8\u5f02\u682a\u7684\u6f5c\u4f0f\u671f\u660e\u663e\u77ed\u4e8e\u91ce\u751f\u682a\uff084.0\u5929vs 6.0\u5929\uff0cP < 0.001\uff09\uff1b\u5728\u975e\u91cd\u75c7\u7ec4\u4e2d\uff0cDelta \u53d8\u5f02\u682a\u7684\u6f5c\u4f0f\u671f\u4ea6\u660e\u663e\u77ed\u4e8e\u91ce\u751f\u682a\uff084.0\u5929vs 7.0\u5929\uff0cp<0.001\uff09\u3002\u6b64\u5916\uff0cDelta\u53d8\u5f02\u682a\u7684\u4f20\u64ad\u901f\u5ea6\u5feb\uff0cDelta\u53d8\u5f02\u682a\u5728\u77ed\u77ed\u5341\u5929\u5185\u4f20\u64ad\u4e86\u56db\u4ee3\uff0c\u5176\u4e2d\u6700\u77ed\u7684\u4ee3\u9645\u4f20\u64ad\u4e0d\u8d85\u8fc7\u4e00\u5929\u3002<\/div>\n\n
\n
\"RmFicvQBAkgB1DMpqWObzasiczMn3Awdr4eXnaAMZNh3MRYSAourHL0jUnJw51bWtwj3qQ76iaFozeYT2jk5ZDpVg\"\/<\/figure><\/div>\n\n

\uff08SARS-CoV-2\u91ce\u751f\u682a\u53caDelta\u53d8\u5f02\u682a\u611f\u67d3\u8005\u7684\u6f5c\u4f0f\u671f\uff09<\/p>\n

3.\u75c5\u6bd2\u8f7d\u91cf\u9ad8<\/div>\n
\u7814\u7a76\u7ed3\u679c\u663e\u793a\uff0c\u6bd4\u8d77\u91ce\u751f\u682a\uff0cDelta\u53d8\u5f02\u682a\u5177\u6709\u8f83\u9ad8\u7684\u75c5\u6bd2\u8f7d\u91cf\uff08Ct\u503c\u4e2d\u4f4d\u657020.6 vs 34.0\uff1bp < 0.001\uff09\uff0c\u5728\u975e\u91cd\u75c7\u3001\u91cd\u75c7\u548c\u5371\u91cd\u75c7\u60a3\u8005\u4e2d\u6b64\u8d8b\u52bf\u4e00\u81f4\u3002Delta\u53d8\u5f02\u682a\u611f\u67d3\u8005\u6838\u9178\u8f6c\u9634\u65f6\u95f4 (Ct\u503c>40) \u4e5f\u66f4\u957f\u3002<\/div>\n\n
\n
\"RmFicvQBAkgB1DMpqWObzasiczMn3Awdr4BQRxnYiaNwWRNzhRqG7pWOax4BlIk9hPakDKRzmtsZpPiaXiaAR9q29SQ\"\/<\/figure><\/div>\n\n
\uff08SARS-CoV-2\u91ce\u751f\u682a\u53caDelta\u53d8\u5f02\u682a\u611f\u67d3\u8005\u7684\u75c5\u6bd2\u8f7d\u91cf\u5cf0\u503c\u53ca\u52a8\u6001\u53d8\u5316\uff09<\/div>\n
4.60\u5c81\u4ee5\u4e0a\u60a3\u8005\u5371\u91cd\u75c7\u98ce\u9669\u66f4\u9ad8<\/div>\n
\u5371\u91cd\u75c7\u60a3\u8005\u4e2d\uff0c\u611f\u67d3Delta\u53d8\u5f02\u682a\u7684\u6240\u6709\u60a3\u8005\u5e74\u9f84\u90fd\u226560\u5c81\uff0c\u800c\u5728\u91ce\u751f\u682a\u4e2d\uff0c\u8fd9\u4e00\u6bd4\u4f8b\u53ea\u670969%\u3002\u5176\u4e2d\uff0c\u611f\u67d3Delta\u53d8\u5f02\u682a\u53d1\u5c55\u4e3a\u5371\u91cd\u75c7\u7684\u98ce\u9669\u662f\u611f\u67d3\u91ce\u751f\u578b\u76842.98\u500d\u3002\u53ef\u4ee5\u8ba4\u4e3a\uff0c\u8001\u5e74\u60a3\u8005\u611f\u67d3Delta\u53d8\u5f02\u682a\u540e\u66f4\u5bb9\u6613\u53d1\u5c55\u81f3\u5371\u91cd\u75c7\u3002<\/div>\n
\n\n
\n
\"RmFicvQBAkgB1DMpqWObzasiczMn3Awdr4Ypxffg5ZiatetkJn9E3MEjgicur9LvFgUTIBrjSv6xYlMAVbZN0lDkcA\"\/<\/figure><\/div>\n\n
\uff08\u9884\u540e\u56e0\u7d20\u7684 Kaplan-Meier \u751f\u5b58\u56fe\uff09<\/div>\n
\u7efc\u4e0a\u6240\u8ff0\uff0c\u672c\u7814\u7a76\u63ed\u793a\u4e86Delta\u53d8\u5f02\u682a\u7684\u5b8c\u6574\u4f20\u64ad\u94fe\uff0c\u603b\u7ed3\u4e86Delta\u53d8\u5f02\u682a\u4f20\u67d3\u6027\u5f3a\u3001\u75c5\u6bd2\u8f7d\u91cf\u9ad8\u3001\u6838\u9178\u8f6c\u9634\u65f6\u95f4\u957f\u3001\u60a3\u75c5\u98ce\u9669\u66f4\u5927\u7b49\u7279\u70b9\u3002\u9664\u4e86\u672c\u6b21\u7814\u7a76\u4e2d\u7684\u75c5\u6bd2\u6d4b\u5e8f\u4e0e\u5206\u6790\uff0c\u534e\u5927\u667a\u9020\u7684\u9ad8\u901a\u91cf\u6d4b\u5e8f\u4eeaMGISEQ-2000\u548cATOPlex\u591a\u91cdPCR\u5e73\u53f0\u8fd8\u53c2\u4e0e\u4e86\u591a\u4e2a\u56fd\u5185\u5916\u65b0\u51a0\u75c5\u6bd2\u7814\u7a76\u9879\u76ee\u3002\u4ee5\u534e\u5927\u667a\u9020\u4e3a\u4ee3\u8868\u7684\u56fd\u4ea7\u6d4b\u5e8f\u5e73\u53f0\uff0c\u4e0d\u4ec5\u79ef\u6781\u53c2\u4e0e\u56fd\u5185\u9632\u75ab\uff0c\u4e5f\u4e3a\u5404\u56fd\u6297\u75ab\u505a\u51fa\u4e86\u91cd\u8981\u8d21\u732e\uff0c\u66f4\u5411\u5168\u7403\u5c55\u793a\u4e86\u4e2d\u56fd\u79d1\u7814\u7684\u529b\u91cf\u3002<\/div>\n
\u00a0<\/div>\n
\u57fa\u4e8e\u9ad8\u6821\u3001\u79d1\u7814\u673a\u6784\u53ca\u4f01\u4e1a\u7684\u52aa\u529b\uff0c\u7814\u7a76\u65b0\u51a0\u75c5\u6bd2\u53ca\u5176\u53d8\u5f02\u682a\u3001\u63ed\u793a\u5176\u4f20\u64ad\u7279\u6027\uff0c\u4e3a\u5168\u56fd\u4e43\u81f3\u5168\u7403\u8fdb\u4e00\u6b65\u6297\u51fb\u75c5\u6bd2\u3001\u9632\u63a7\u75ab\u60c5\u63d0\u4f9b\u4e86\u53ef\u9760\u7684\u7406\u8bba\u4f9d\u636e\u548c\u5148\u8fdb\u7ecf\u9a8c\uff0c\u662f\u6709\u6548\u5bf9\u6297\u75ab\u60c5\u7684\u524d\u63d0\u3002<\/div>\n
\u00a0<\/div>\n
\u6269\u5c55\u9605\u8bfb<\/div>\n
\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5\uff08No.157\uff09<\/a><\/div>\n
\u201c\u4f20\u64ad\u4e13\u4e1a \u516c\u76ca\u4e3a\u6c11\u201d\u884c\u7814\u5927\u793c\u5305<\/a><\/div>\n
2021\u80bf\u7624\u84dd\u76ae\u4e66\u514d\u8d39\u7533\u9886<\/a><\/div>\n
\u00a0<\/div>\n
\u6587\u7ae0 | Kathy<\/div>\n
\u7f16\u8f91 | Kathy<\/div>\n
\u5173\u952e\u8bcd | \u534e\u5927\u667a\u9020\u6d4b\u5e8f\u5e73\u53f0<\/div>\n
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\u00a0<\/div>\n
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