{"id":8801,"date":"2022-08-10T18:10:00","date_gmt":"2022-08-10T10:10:00","guid":{"rendered":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/08\/10\/529754\/"},"modified":"2026-04-01T10:03:48","modified_gmt":"2026-04-01T02:03:48","slug":"529754","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/08\/10\/529754\/","title":{"rendered":"\u4e00\u516c\u65a4DNA\u53ef\u5b58\u50a8\u5168\u7403\u6570\u636e\u662f\u5982\u4f55\u505a\u5230\u7684\uff1f | \u300aDNA\u5b58\u50a8\u84dd\u76ae\u4e66\u300b\u8fde\u8f7d\uff082\uff09"},"content":{"rendered":"<p><!-- wechat_content_hash: 4a6533390b8b813d --><\/p>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCFPSfZ6tZaXGnzKEHDbYsficYPHdcUZ3CUjqA2DDdJ6GPVEXSib6QcbMLFB34Icf9b45I3GQClsNnQ.jpeg\" 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Church\u56e2\u961f\u9996\u6b21\u9a8c\u8bc1\u4e86\u89c4\u6a21\u5316DNA\u5b58\u50a8\u7684\u6982\u5ff5\uff0c\u6bcf\u5e74\u4e0eDNA\u5b58\u50a8\u4fe1\u606f\u7f16\u7801\u65b9\u6cd5\u76f8\u5173\u7684\u7814\u7a76\u6587\u732e\u9010\u5e74\u9012\u589e\u3002\u7814\u7a76\u601d\u8def\u4e3b\u8981\u805a\u7126\u4e8e\u63d0\u5347\u4fe1\u606f\u5bc6\u5ea6\u3001\u751f\u7269\u5316\u5b66\u7ea6\u675f\u7684\u517c\u5bb9\u6027\u3001\u9519\u8bef\u7ea0\u6b63\u3001\u4e0d\u540c\u5b58\u50a8\u529f\u80fd\u9002\u914d\u6027\uff08\u5982\u4fe1\u606f\u7684\u968f\u673a\u8bfb\u53d6\u3001\u641c\u7d22\u3001\u9884\u52a0\u8f7d\u7b49\uff09\u4ee5\u53ca\u5b89\u5168\u6027\u7b49\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u73b0\u6709\u5df2\u53d1\u8868\u7684\u7f16\u7801\u7b97\u6cd5\u7684\u5de5\u4f5c\u5927\u81f4\u53ef\u5206\u4e3a\u4e24\u7c7b:<\/div>\n<div>\u7b2c\u4e00\u7c7b\u4e3a\u57fa\u4e8e\u53d7\u9650\u7684\u57fa\u672c\u6620\u5c04\u5173\u7cfb\u7684\u7f16\u7801\u7b97\u6cd5\uff0c\u5305\u62ecChurch\u7f16\u7801\u7b97\u6cd5\u3001Goldman\u7f16\u7801\u7b97\u6cd5\u3001Grass\u7f16\u7801\u7b97\u6cd5\u3001Blawat\u7f16\u7801\u7b97\u6cd5\u7b49\u3002\u8fd9\u4e9b\u7f16\u7801\u7b97\u6cd5\u5728\u8003\u8651\u5355\u78b1\u57fa\u91cd\u590d\u548c\/\u6216\u5176\u4ed6\u7684\u7ea6\u675f\u8981\u6c42\u4e0b\u786e\u5b9a\u4e86\u6bd4\u7279\u4e0e\u53d7\u9650\u78b1\u57fa\u4e4b\u95f4\u7684\u6620\u5c04\u89c4\u5219\u3002\u901a\u8fc7\u727a\u7272\u4e00\u5b9a\u7684\u7f16\u7801\u4fe1\u606f\u5bc6\u5ea6\uff0c\u5229\u7528\u56fa\u5b9a\u6620\u5c04\u89c4\u5219\uff0c\u907f\u514d\u4e86\u51fa\u73b0\u5355\u78b1\u57fa\u91cd\u590d\u7684\u53ef\u80fd\u6027\u3002<\/div>\n<div>\u7b2c\u4e8c\u7c7b\u4e3a\u5728\u57fa\u672c\u6620\u5c04\u5173\u7cfb\u57fa\u7840\u4e0a\u589e\u52a0\u7b5b\u9009\u8fc7\u6ee4\u6b65\u9aa4\u7684\u7f16\u7801\u7b97\u6cd5\uff0c\u5305\u62ecDNA Fountain\u55b7\u6cc9\u7801\u548cYin-Yang\u53cc\u7f16\u7801\u7b97\u6cd5\u7b49\uff0c\u5229\u7528\u6587\u4ef6\u4e2d\u4e8c\u8fdb\u5236\u4fe1\u606f\u7247\u6bb5\u7684\u7ec4\u5408\u591a\u6837\u6027\uff0c\u751f\u6210\u66f4\u591a\u4e0d\u540c\u7684DNA\u5e8f\u5217\u3002\u5728\u5b8c\u6210\u57fa\u672c\u6620\u5c04\u7f16\u7801\u540e\uff0c\u4f1a\u9488\u5bf9\u751f\u6210DNA\u5e8f\u5217\u8fdb\u884c\u751f\u5316\u7ea6\u675f\u6761\u4ef6\u4e0b\u5e8f\u5217\u7b5b\u9009\u8fc7\u6ee4\uff0c\u5b8c\u5168\u6ee1\u8db3\u9884\u5148\u8bbe\u5b9a\u7684\u751f\u5316\u7ea6\u675f\u6761\u4ef6\uff0c\u5982GC\u542b\u91cf\u3001\u5355\u78b1\u57fa\u91cd\u590d\u3001\u4e8c\u7ea7\u7ed3\u6784\u81ea\u7531\u80fd\u7b49\u3002<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwIvzWHJpGCxKR9LSd2lVicBFI8LUsler06jHSCUGYecZKsGlibsXC0USA.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwIvzWHJpGCxKR9LSd2lVicBFI8LUsler06jHSCUGYecZKsGlibsXC0USA\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>Church\u7f16\u7801\u7b97\u6cd5\uff1a2012\u5e74\uff0cGeorge Church\u56e2\u961f\u9996\u6b21\u9a8c\u8bc1\u4e86\u89c4\u6a21\u5316DNA\u5b58\u50a8\u7684\u6982\u5ff5\uff0c\u5e76\u4f30\u8ba1\u4e86DNA\u5b58\u50a8\u7684\u7406\u8bba\u5b58\u50a8\u5bc6\u5ea6(5.5Pb\/mm3\u6216455EB\/g)\u3002\u8be5\u56e2\u961f\u7387\u5148\u63d0\u51fa\u4e86\u201c\u6bd4\u7279-\u78b1\u57fa\u201d\u7684\u7b80\u5355\u7f16\u7801\u8fc7\u7a0b\uff0c\u5373Church\u7f16\u7801\u7b97\u6cd5\u3002\u8be5\u65b9\u6cd5\u53ef\u4ee5\u5b8c\u5168\u907f\u514d\u4e09\u4e2a\u4ee5\u4e0a\u8fde\u7eed\u78b1\u57fa\u91cd\u590d\u7684\u60c5\u51b5\uff0c\u4f46\u5bf9\u7279\u5b9a\u6570\u636e\u7ed3\u6784\uff0c\u4e00\u65e6\u6620\u5c04\u5173\u7cfb\u786e\u5b9a\uff0c\u5219\u65e0\u6cd5\u5b9e\u73b0\u5bf9GC\u542b\u91cf\u7684\u8c03\u63a7\u3002<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwqlmm2bx6geykUfIH35qaTal4XtbAYDvo8FzM5wYjK8Lgy6Ml7gWzQA.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwqlmm2bx6geykUfIH35qaTal4XtbAYDvo8FzM5wYjK8Lgy6Ml7gWzQA\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>Goldman\u7f16\u7801\u7b97\u6cd5\uff1a\u4e3a\u4e86\u76f4\u63a5\u6d88\u9664\u5355\u78b1\u57fa\u91cd\u590d\u5bf9\u5408\u6210\u6216\u6d4b\u5e8f\u8fc7\u7a0b\u7684\u5f71\u54cd\uff0c2013\u5e74Nick Goldman\u56e2\u961f\u63d0\u51fa\u4e86\u4e00\u79cd\u57fa\u4e8e\u970d\u592b\u66fc\u7f16\u7801\u7684\u8f6e\u8f6c\u7f16\u7801\u89c4\u5219\u3002\u4e5f\u662f\u9996\u4e2a\u5c06\u6bd4\u7279-\u78b1\u57fa\u4fe1\u606f\u5bc6\u5ea6\u7eb3\u5165\u8003\u8651\u7684\u7f16\u7801\u65b9\u6cd5\u3002\u540c\u65f6\u5b83\u4e5f\u5229\u7528\u5206\u6bb5\u91cd\u590d\u4fdd\u5b58\u7684\u539f\u7406\uff0c\u5c06\u6bcf\u4e2a\u4fe1\u606f\u57284\u4e2a\u4e0d\u540c\u7684\u5206\u5b50\u4e2d\u8fdb\u884c\u5907\u4efd\u62f7\u8d1d\uff0c\u5c3d\u7ba1\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u589e\u52a0\u4e86\u6210\u672c\uff0c\u4f46\u5927\u5927\u63d0\u9ad8\u4e86\u7a33\u5b9a\u6027\u3002\u540e\u7eed\u7684Borholt\u7b49\u4eba\u5bf9\u8be5\u65b9\u6cd5\u8fdb\u884c\u4e86\u6539\u8fdb\uff0c\u5229\u7528\u5f02\u6216\u8fd0\u7b97\u5927\u5927\u964d\u4f4e\u4e86\u5907\u4efd\u62f7\u8d1d\u6216\u8005\u5197\u4f59\u7684\u4fe1\u606f\u91cf\u3002<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwS7ktbxZSol9pVtF0brV0YNfRDuTDaEhbyWyIykib938jqQxN7Xz4MXw.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwS7ktbxZSol9pVtF0brV0YNfRDuTDaEhbyWyIykib938jqQxN7Xz4MXw\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>Grass\u7f16\u7801\u7b97\u6cd5\uff1a2015\u5e74\uff0cRobert N. Grass\u56e2\u961f\u5c06\u6709\u9650\u57df\u4e0e\u78b1\u57fa\u4e09\u8054\u4f53\u8fdb\u884c\u5173\u8054\uff0c\u63d0\u51fa\u4e86\u53ef\u907f\u514d\u957f\u5ea6\u5927\u4e8e3\u7684\u5355\u78b1\u57fa\u91cd\u590d\u7684\u7f16\u7801\u7b97\u6cd5\u3002\u8be5\u65b9\u6cd5\u53ef\u4ee5\u6709\u6548\u907f\u514d\u8fde\u7eed\u4e09\u4e2a\u4ee5\u4e0a\u7684\u5355\u78b1\u57fa\u91cd\u590d\uff0c\u5176\u7406\u8bba\u4fe1\u606f\u5bc6\u5ea6\u53ef\u4ee5\u8fbe\u52301.78\u6bd4\u7279\/\u78b1\u57fa\u3002\u5728\u7f16\u7801\u8fc7\u7a0b\u4e2d\uff0cGrass\u7b49\u4eba\u9996\u6b21\u5f15\u5165\u4e86\u4fe1\u606f\u6280\u672f\u4e2d\u7684\u7ea0\u9519\u7f16\u7801\uff0c\u62d3\u5c55\u4e86DNA\u5b58\u50a8\u7684\u7f16\u7801\u6a21\u5757\uff0c\u4e3a\u6b64\u540e\u7684DNA\u5b58\u50a8\u66f4\u51c6\u786e\u5730\u5e94\u5bf9DNA\u5e8f\u5217\u5728\u5408\u6210\u3001\u6269\u589e\u3001\u6d4b\u5e8f\u4e2d\u65e0\u6cd5\u907f\u514d\u7684\u78b1\u57fa\u66ff\u6362\u9519\u8bef\u63d0\u4f9b\u4e86\u89e3\u51b3\u65b9\u6848\u3002<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwQKAJQ5aNuXCUyeBickdib9RylMjHa2YBPJW2haArygniajYJwg7BVkdMA.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwQKAJQ5aNuXCUyeBickdib9RylMjHa2YBPJW2haArygniajYJwg7BVkdMA\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>Blawat\u7f16\u7801\u7b97\u6cd5\uff1aMeinolf Blawat\u53ca\u5176\u540c\u4e8b\u57282016\u5e74\u53d1\u5e03\u4e86\u4e00\u79cd\u7f16\u7801\u7b97\u6cd5\uff0c\u4ee5\u5904\u7406DNA\u6d4b\u5e8f\u3001\u6269\u589e\u3001\u548c\u5408\u6210\u8fc7\u7a0b\u5f15\u5165\u7684\u9519\u8bef\u3002\u8be5\u65b9\u6cd5\u4ee5\u5b57\u8282\u800c\u975e\u6bd4\u7279\u4f5c\u4e3a\u78b1\u57fa\u8f6c\u6362\u7684\u57fa\u672c\u5355\u5143\uff0c\u5c06\u4e00\u5b57\u8282\u4fe1\u606f\uff08\u957f\u5ea6\u4e3a8\uff09\u8f6c\u6362\u4e3a\u957f\u5ea6\u4e3a5\u7684DNA\u5e8f\u5217\u4fe1\u606f\u3002Blawat\u7f16\u7801\u4e00\u5b9a\u7a0b\u5ea6\u4e0a\u7ee7\u627f\u4e86Church\u7f16\u7801\u78b1\u57fa\u4e92\u6362\u7684\u601d\u60f3\uff0c\u5728\u7ea0\u9519\u65b9\u9762\u5e76\u6ca1\u6709\u5229\u7528\u4fe1\u606f\u5b66\u4e2d\u7684\u7ea0\u9519\u7801\uff0c\u800c\u662f\u5229\u7528\u81ea\u8eab\u7f16\u7801\u7b97\u6cd5\u7684\u7279\u70b9\uff0c\u901a\u8fc7\u53cd\u5411\u63a8\u5bfc\u53bb\u9664\u9519\u8bef\u9009\u9879\u8fbe\u5230\u7ea0\u9519\u7684\u76ee\u7684\u3002<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbw1iadPIEsfgJ1LxorYvb8YSYfE8Kic9iac6PuDBhjO0S7d3hXR08gwuEtw.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbw1iadPIEsfgJ1LxorYvb8YSYfE8Kic9iac6PuDBhjO0S7d3hXR08gwuEtw\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>DNA Fountain\u55b7\u6cc9\u7801\uff1a2017\u5e74\uff0c\u54e5\u4f26\u6bd4\u4e9a\u5927\u5b66\u7684\u7814\u7a76\u4eba\u5458Yaniv Erlich\u548cDina Zielinski\u63d0\u51fa\u4e86\u57fa\u4e8eLuby\u53d8\u6362\u7801\uff08Luby Transform\uff09\u7684\u7f16\u7801\u7b97\u6cd5\u201cDNA \u55b7\u6cc9\u7801\u201d\u3002Luby\u53d8\u6362\u7801\u4f5c\u4e3a\u9996\u4e2a\u5b9e\u7528\u6027\u55b7\u6cc9\u7801\uff0c\u53ef\u4ee5\u4ece\u4e00\u7ec4\u7ed9\u5b9a\u7684\u6e90\u6570\u636e\u5305\u4e2d\u4ea7\u751f\u4e00\u4e32\u65e0\u9650\u7684\u7f16\u7801\u7b26\u53f7\u5e8f\u5217\uff0c\u5728\u7406\u60f3\u60c5\u51b5\u4e0b\uff0c\u53ea\u9700\u83b7\u5f97\u5927\u5c0f\u548c\u6e90\u6570\u636e\u5305\u603b\u91cf\u76f8\u540c\u6216\u7a0d\u5927\u7684\u4efb\u610f\u7f16\u7801\u7b26\u53f7\u5b50\u96c6\uff0c\u4fbf\u53ef\u6062\u590d\u6e90\u6570\u636e\u4fe1\u606f\u3002\u4e0e\u4e0a\u8ff0\u7b97\u6cd5\u4e0d\u540c\u7684\u662f\uff0c\u8be5\u7b97\u6cd5\u5e76\u672a\u5c06\u7ea6\u675f\u6761\u4ef6\u5199\u5165\u6620\u5c04\u89c4\u5219\u4e2d\uff0c\u800c\u662f\u901a\u8fc7\u7b5b\u9009\u673a\u5236\u4f7f\u5f97\u6700\u7ec8\u83b7\u5f97\u7684DNA\u5e8f\u5217\u6ee1\u8db3\u7ea6\u675f\u8981\u6c42\u3002<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwjEzTFS4IeUJBvGtXf7XUrcgZTsibNDrPMicVSFjent0x83DKwucYibicicw.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwjEzTFS4IeUJBvGtXf7XUrcgZTsibNDrPMicVSFjent0x83DKwucYibicicw\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>Yin-Yang\u9634\u9633\u53cc\u7f16\u7801\u7b97\u6cd5\uff1a\u53c2\u8003\u7b5b\u9009\u64cd\u4f5c\u548cGoldman\u7f16\u7801\u7b97\u6cd5\uff0c\u6df1\u5733\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u7684\u5e73\u8d28\u7b49\u7814\u7a76\u4eba\u5458\u4e3b\u5bfc\u63d0\u51fa\u4e86Yin-Yang\u9634\u9633\u53cc\u7f16\u7801\u7b97\u6cd5\u3002\u76f8\u6bd4DNA Fountain\u7f16\u7801\u7b97\u6cd5\uff0c\u8be5\u65b9\u6cd5\u5e76\u975e\u57fa\u4e8e\u968f\u673a\u6570\u79cd\u5b50\u548c\u5f02\u6216\u64cd\u4f5c\u83b7\u5f97DNA\u5e8f\u5217\uff0c\u800c\u662f\u57fa\u4e8e\u67d0\u79cd\u9009\u4e2d\u7684\u89c4\u5219\u7c07\uff08\u5171\u8ba16144\u79cd\uff09\uff0c\u57fa\u4e8e\u201c\u9634\u201d\u548c\u201c\u9633\u201d\u4e24\u79cd\u8f6e\u8f6c\u89c4\u5219\uff0c\u5c06\u4e24\u6761\u4e8c\u8fdb\u5236\u5b50\u5e8f\u5217\u8f6c\u6362\u4e3a\u4e00\u6761DNA\u5e8f\u5217\u3002\u6b64\u5916\uff0c\u5982\u679c\u5728\u4e00\u5b9a\u8fed\u4ee3\u6b21\u6570\u540e\u4ecd\u7136\u627e\u4e0d\u5230\u6ee1\u8db3\u8981\u6c42\u7684DNA\u5e8f\u5217\uff0c\u5219\u9009\u4e2d\u4e00\u6761\u4e8c\u8fdb\u5236\u5b50\u5e8f\u5217\u5e76\u5728\u5916\u90e8\u751f\u6210\u4e00\u6761\u968f\u673a\u7684\u6bd4\u7279\u5e8f\u5217\u8fdb\u884c\u9634\u9633\u8f6e\u8f6c\u64cd\u4f5c\uff0c\u83b7\u5f97\u4e00\u5b9a\u6ee1\u8db3\u8981\u6c42\u7684DNA\u5e8f\u5217\u3002<\/div>\n<div><\/div>\n<div>\u9634\u9633\u7801\u501f\u9274\u4e86\u81ea\u7136\u754c\u4e2dDNA\u53cc\u94fe\u7279\u5f81\u4e0e\u4e2d\u56fd\u53e4\u4ee3\u54f2\u5b66\u7684\u9634\u9633\u4e24\u9762\u601d\u60f3\uff0c\u540c\u65f6\u7ed3\u5408\u4e86Goldman\u7f16\u7801\u7684\u8f6e\u8f6c\u601d\u8def\u4e0eDNA\u55b7\u6cc9\u7801\u7684\u7b5b\u9009\u601d\u8def\u3002\u5b83\u53ef\u4ee5\u8fbe\u5230\u4e0eDNA\u55b7\u6cc9\u7801\u76f8\u5ab2\u7f8e\u7684\u9ad8\u4fe1\u606f\u5bc6\u5ea6\uff081.95\u6bd4\u7279\/\u78b1\u57fa\uff09\uff0c\u5e76\u9488\u5bf9DNA\u5b58\u50a8\u4e2d\u4fe1\u606f\u4f20\u8f93\u5f02\u6b65\u8fd9\u4e00\u6709\u522b\u4e8e\u4f20\u7edf\u4fe1\u606f\u4f20\u8f93\u4f53\u7cfb\u7684\u7279\u70b9\uff0c\u4e0d\u540c\u4fe1\u606f\u5305\u4e4b\u95f4\u76f8\u4e92\u72ec\u7acb\uff0c\u5e76\u672a\u5efa\u7acb\u89e3\u7801\u5173\u8054\u6027\u3002\u8fd9\u4e00\u505a\u6cd5\u4f7f\u5f97\u5176\u5728\u5e94\u5bf9\u78b1\u57fa\u9519\u8bef\u4e0e\u5e8f\u5217\u4e22\u5931\u7684\u8868\u73b0\u4e0a\u6bd4DNA\u55b7\u6cc9\u7801\u6709\u4e86\u660e\u663e\u4f18\u52bf\u3002\u5728\u8fdb\u4e00\u6b65\u7684\u5b9e\u9a8c\u9a8c\u8bc1\u4e2d\uff0c\u9634\u9633\u7801\u53ef\u4ee5\u5728\u4f4e\u5206\u5b50\u62f7\u8d1d\u6570\uff08\u2264100\uff09\u4e0b\u83b7\u5f97\u66f4\u9ad8\u7684\u6570\u636e\u6062\u590d\u7387\uff08\u5b9e\u9a8c\u6570\u636e\u8868\u5f81\u53ef\u8fbe\u523088%\uff09\u3002\u9634\u9633\u7801\u4e5f\u63d0\u4f9b\u4e86\u591a\u8fbe\u6570\u5343\u79cd\u7684\u7f16\u7801\u89c4\u5219\uff0c\u7ed3\u5408\u4e8c\u8fdb\u5236\u7247\u6bb5\u7075\u6d3b\u7684\u7ec4\u5408\u65b9\u5f0f\uff0c\u8be5\u65b9\u6cd5\u53ef\u4ee5\u5e94\u7528\u4e8e\u591a\u79cd\u573a\u666f\uff0c\u5305\u62ec\u6587\u4ef6\u7684\u5f52\u6863\u3001\u6570\u636e\u7684\u52a0\u5bc6\u7b49\u7b49\u3002<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwLE3hbUNxgzL0JtyuehanPkjKxicKqy1HGDkxhOkHylk16XNDHjI14Aw.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwLE3hbUNxgzL0JtyuehanPkjKxicKqy1HGDkxhOkHylk16XNDHjI14Aw\"\/><\/figure><\/div>\n\n<div>\u76ee\u524d\u516c\u5f00\u7684DNA\u5b58\u50a8\u7f16\u7801\u7b97\u6cd5\u6240\u91c7\u7528\u7684\u7f16\u7a0b\u8bed\u8a00\u3001\u7f16\u7801\u6240\u8bbe\u5b9a\u7684\u6280\u672f\u53c2\u6570\u5404\u4e0d\u76f8\u540c\uff0c\u4e0d\u5229\u4e8e\u57fa\u4e8e\u5df2\u6709\u7814\u7a76\u57fa\u7840\u7684\u540e\u7eed\u5f00\u53d1\u4f18\u5316\uff0c\u9488\u5bf9\u4e0d\u540c\u7c7b\u578b\u6570\u636e\u6587\u4ef6\u7684\u6700\u9002\u914d\u7b97\u6cd5\u9009\u62e9\u4e5f\u7f3a\u4e4f\u76f8\u5e94\u7684\u8bc4\u4ef7\u6216\u662f\u9009\u62e9\u6807\u51c6\uff0c\u4ece\u800c\u963b\u788d\u4e86\u8be5\u9886\u57df\u7684\u4ea4\u6d41\u4e0e\u53d1\u5c55\u3002\u4e3a\u89e3\u51b3\u8fd9\u4e2a\u95ee\u9898\uff0c2021 \u5e74\uff0c\u6df1\u5733\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u7814\u7a76\u56e2\u961f\u53d1\u8868\u9488\u5bf9DNA\u5b58\u50a8\u4e0d\u540c\u7f16\u7801\u7b97\u6cd5\u7684\u96c6\u6210\u4e0e\u8bc4\u4ef7\u5e73\u53f0Chamaeleo\u7cfb\u7edf\u7684\u7814\u7a76\u6210\u679c\u3002Chamaeleo\u7cfb\u7edf\u7531\u8f6c\u7801\u6a21\u5757\u3001\u7ea0\u9519\u6a21\u5757\u548c\u6d41\u7a0b\u6a21\u5757\u6784\u6210\u3002\u5176\u4e2d\uff0c\u6d41\u7a0b\u6a21\u5757\u7528\u4e8e\u5b9e\u9645\u8f6c\u7801\/\u8bc4\u4f30\u4efb\u52a1\u7684\u6267\u884c\uff0c\u8f6c\u7801\u6a21\u5757\u4e2d\u7684\u8f6c\u7801\u7b97\u6cd5\u4ee5\u53ca\u7ea0\u9519\u6a21\u5757\u4e2d\u7684\u7ea0\u9519\u7801\u90fd\u4f1a\u901a\u8fc7\u5b9e\u4f8b\u5316\u7684\u65b9\u5f0f\u88ab\u6d41\u7a0b\u6a21\u5757\u4e2d\u7684\u5177\u4f53\u6d41\u7a0b\u6240\u4f7f\u7528\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u9664Chamaeleo\u5e73\u53f0\u5916\uff0c\u4e2d\u79d1\u78b3\u5143\u8054\u5408\u4e2d\u79d1\u9662\u6df1\u5733\u5148\u8fdb\u6280\u672f\u7814\u7a76\u9662\u7814\u7a76\u56e2\u961f\u53d1\u5e03\u4e86\u9996\u6b3eDNA\u6570\u636e\u5b58\u50a8\u5728\u7ebf\u7f16\u89e3\u7801\u8f6f\u4ef6\u2014\u2014\u201c\u963f\u7ae5\u6728\uff08ATOM1.0\uff09\u201d\u3002\u6839\u636e\u5b98\u7f51\u4ecb\u7ecd\uff0c\u8be5\u8f6f\u4ef6\u4e3a\u7528\u6237\u63d0\u4f9b\u4e86\u53cb\u597d\u7684\u64cd\u4f5c\u754c\u9762\uff0c\u53ef\u5728\u4e8c\u8fdb\u5236\u6570\u636e\u6587\u4ef6\u548cA\/T\/C\/G\u76844\u78b1\u57fa\u6838\u82f7\u9178\u7f16\u7801\u7684\u81ea\u7531\u8f6c\u6362\uff0c\u65b9\u4fbf\u8fdb\u884c\u6570\u636e\u5b58\u50a8\u6216\u8bfb\u53d6\u3002\u4e0e\u4f20\u7edf\u8ba1\u7b97\u673a\u95f4\u7684\u6570\u636e\u8f6c\u6362\u548c\u901a\u8baf\u4e0d\u540c\uff0c\u8be5\u8f6f\u4ef6\u5b9e\u73b0\u4e86\u8ba1\u7b97\u673a\u548c\u751f\u7269\u4f53\u9057\u4f20\u4fe1\u606f\u4e4b\u95f4\u7684\u6570\u636e\u4ea4\u4e92\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u6b64\u5916\uff0c\u503c\u5f97\u5173\u6ce8\u7684\u65e0\u6bd4\u7387\u7ea0\u5220\u7801\u8f6f\u4ef6\u67b6\u6784NOREC4DNA\uff0c\u662f\u9488\u5bf9\u65e0\u6bd4\u7387\u7ea0\u5220\u7801\uff08rateless erasure codes\uff0c\u4f8b\u5982DNA Fountain\uff09\u5f00\u53d1\u7684\u4e00\u5957\u4f7f\u7528\u3001\u6d4b\u8bd5\u3001\u6bd4\u8f83\u548c\u6539\u8fdb\u7684\u8f6f\u4ef6\u67b6\u6784\u3002\u8be5\u67b6\u6784\u4e2d\u7740\u91cd\u5206\u6790\u4e86\u5305\u542b\u5362\u6bd4\u53d8\u6362\u7801\u3001\u5728\u7ebf\u7f16\u7801\uff08Online Code\uff09\u3001\u65cb\u98ce\u7f16\u7801\uff08Rapid tornado Code\uff09\u5728\u4e0d\u540c\u53c2\u6570\u60c5\u51b5\u4e0b\u7684\u89e3\u7801\u60c5\u51b5\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u4e09\u3001DNA\u5b58\u50a8\u7684\u7b2c\u4e8c\u6b65\uff1aDNA\u5408\u6210<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwnTez0TEdT9VbvKItUjOrJ4dTzJfVEmITiamLMMeFToP5EByW0scUyOA.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwnTez0TEdT9VbvKItUjOrJ4dTzJfVEmITiamLMMeFToP5EByW0scUyOA\"\/><\/figure><\/div>\n\n<div style=\"text-align: center;\">\u56fe\uff1aDNA\u5408\u6210\u6280\u672f\u4e0e\u4eea\u5668\u7814\u53d1\u8fdb\u5c55\u6982\u8ff0\uff08\u6765\u6e90\/DNA\u5b58\u50a8\u84dd\u76ae\u4e66\u300b\uff0c\u4e0b\u540c<\/div>\n<div>DNA\u5408\u6210\u662fDNA\u5b58\u50a8\u4e2d\u7684\u6838\u5fc3\u6280\u672f\u4e4b\u4e00\uff0c\u5176\u6548\u7387\u4e0e\u6210\u672c\u6781\u5927\u5730\u5f71\u54cd\u7740DNA\u5b58\u50a8\u6280\u672f\u7684\u89c4\u6a21\u5316\u5e94\u7528\u3002\u4eba\u5de5\u5408\u6210DNA\u662f\u57fa\u4e8e\u5316\u5b66\u6cd5\u6216\u751f\u7269\u6cd5\uff0c\u5c06\u8fd9\u4e9b\u8131\u6c27\u6838\u82f7\u9178\u5355\u4f53\u6309\u4e8b\u5148\u786e\u5b9a\u7684\u987a\u5e8f\u4f9d\u6b21\u8fde\u63a5\u8d77\u6765\uff0c\u5373DNA\u5408\u6210\u3002\u5e38\u89c4DNA\u5408\u6210\u65b9\u6cd5\u4ee5\u5355\u94fe\u5be1\u6838\u82f7\u9178\u5408\u6210\u4e3a\u57fa\u7840\uff0c\u56e0\u6b64\u672c\u8282\u4e2d\u7684DNA\u5408\u6210\u5982\u65e0\u7279\u6b8a\u8bf4\u660e\uff0c\u5747\u6307\u7684\u662f\u5355\u94fe\u5be1\u6838\u82f7\u9178\u5408\u6210\u3002<\/div>\n<div>\u00a0<\/div>\n<div>DNA\u7684\u5408\u6210\u6309\u539f\u7406\u4e00\u822c\u5206\u4e3a\u5316\u5b66\u6cd5\u5408\u6210\u548c\u751f\u7269\u6cd5\u5408\u6210\u3002\u5316\u5b66\u6cd5\u5408\u6210\u4e3b\u8981\u57fa\u4e8e\u4e9a\u78f7\u9170\u80fa\u6cd5\uff0c\u5176\u4e2d\u63a7\u5236\u65b9\u6cd5\u5305\u542b\u5149\u5316\u5b66\u6cd5\u3001\u7535\u5316\u5b66\u6cd5\u3001\u55b7\u58a8\u6253\u5370\u6cd5\u3001\u96c6\u6210\u7535\u8def\u63a7\u5236\u7b49\u3002\u751f\u7269\u6cd5\u5408\u6210\u5305\u62ec\u57fa\u4e8eTdT\u3001TdT-dNTP\u4ea4\u8054\u4f53\u4ee5\u53ca\u6df7\u5408\u9176\u4ecb\u5bfc\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u5316\u5b66\u5408\u6210\uff1a\u5be1\u6838\u82f7\u9178\u5316\u5b66\u5408\u6210\u8d77\u6b65\u4e8e\u4e8c\u5341\u4e16\u7eaa\u56db\u5341\u5e74\u4ee3\u672b\u30021955 \u5e74\uff0c\u5251\u6865\u5927\u5b66\u7684 Todd\u5b9e\u9a8c\u5ba4\uff0c\u7b2c\u4e00\u6b21\u7528\u5316\u5b66\u6cd5\u6210\u529f\u5408\u6210\u4e86\u7b80\u5355\u4e8c\u805a\u5be1\u6838\u82f7\u9178\uff0c\u5e76\u4e8e1957\u5e74\u83b7\u5f97\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956(\u5982\u4e0b\u56fe)\u30021965\u5e74\uff0cKhorana\u7b49\u5229\u7528\u5316\u5b66\u65b9\u6cd5\u5927\u91cf\u5408\u6210\u8131\u6c27\u6838\u82f7\u7684\u5355\u4e00\u805a\u5408\u7269\u6216\u4e8c\u79cd\u3001\u4e09\u79cd\u8131\u6c27\u6838\u82f7\u7684\u91cd\u590d\u5e8f\u5217\uff0c\u5e76\u4eba\u5de5\u5408\u6210\u4e86\u516d\u5341\u56db\u79cd\u6838\u7cd6\u4e09\u7cd6\u82f7\u7528\u4e8e\u7814\u7a76\u86cb\u767d\u8d28\u7684\u751f\u7269\u5408\u6210\u8fc7\u7a0b\uff0c\u4ece\u800c\u786e\u5b9a\u4e86\u6c28\u57fa\u9178\u7684\u4e09\u8054\u5bc6\u7801\u5b50\uff0c \u56e0\u6b64\u83b7\u5f971968\u5e74\u7684\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u4e8c\u5341\u4e16\u7eaa\u516d\u5341\u81f3\u4e03\u5341\u5e74\u4ee3\uff0c\u5be1\u6838\u82f7\u9178\u7684\u5316\u5b66\u5408\u6210\u65b9\u6cd5\u4e0d\u65ad\u88ab\u5b8c\u5584\uff0c\u4e3b\u8981\u5305\u62ec\u6539\u5584\u4e9a\u78f7\u9170\u80fa\u5355\u4f53\u7684\u7a33\u5b9a\u6027\u548c\u53cd\u5e94\u6d3b\u6027\u4ee5\u63d0\u9ad8\u5355\u4f53\u5076\u8054\u6b65\u6548\u7387\uff0c\u4f18\u5316\u4fdd\u62a4\u57fa\u56e2\u7684\u53cd\u5e94\u6d3b\u6027\u53ca\u4ea7\u7269\u7684\u7a33\u5b9a\u6027\u4ee5\u63d0\u9ad8\u6c27\u5316\u73af\u8282\u7684\u6c27\u5316\u6548\u7387\u7b49\u3002\u76ee\u524d\u51e0\u4e4e\u6240\u6709\u7684\u5de5\u4e1a\u5316\u7684Oligo\u5408\u6210\uff0c\u5747\u8d77\u6e90\u4e8e1987\u5e74\u7531\u7f8e\u56fd\u79d1\u5b66\u5bb6Marvin H. Caruthers\u53d1\u660e\u7684\u201c\u56fa\u76f8\u4e9a\u78f7\u9170\u80fa\u4e09\u916f\u6cd5\u201d\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u7136\u800c\uff0c\u7531\u4e8e\u6bcf\u4e00\u6b65\u5316\u5b66\u53cd\u5e94\u7684\u4e0d\u5b8c\u5168\u6027\u548c\u526f\u53cd\u5e94\u7684\u53d1\u751f\uff0c\u968f\u7740\u5be1\u6838\u82f7\u9178\u5408\u6210\u94fe\u7684\u5ef6\u957f\uff0c\u5408\u6210\u9519\u8bef\u7387\u6025\u5267\u4e0a\u5347\uff0c\u5408\u6210\u4ea7\u7269\u5f97\u7387\u4e5f\u663e\u8457\u4e0b\u964d\u3002\u6b64\u5916\uff0c\u7531\u4e8e\u5408\u6210\u8fc7\u7a0b\u4e2d\u9700\u8981\u5927\u91cf\u4f7f\u7528\u6709\u6bd2\u5316\u5b66\u8bd5\u5242\uff0c\u6240\u4ea7\u751f\u7684\u5e9f\u6db2\u3001\u5e9f\u6c14\u4e5f\u9700\u8981\u7279\u6b8a\u5904\u7406\u3002\u4e3a\u6b64\uff0c\u8fd1\u5e74\u6765\u79d1\u7814\u4eba\u5458\u5f00\u53d1\u51fa\u5f88\u591a\u65e8\u5728\u63d0\u9ad8\u5408\u6210\u6548\u7387\u3001\u964d\u4f4e\u526f\u53cd\u5e94\u53d1\u751f\u7387\u7684\u65b9\u6cd5\uff0c\u5e76\u5c1d\u8bd5\u521b\u65b0\u7814\u53d1\u4e0d\u4f9d\u8d56\u6709\u6bd2\u5316\u5b66\u8bd5\u5242\u7684\u5408\u6210\u65b9\u6cd5\u3002\u5305\u62ec\u4e9a\u78f7\u9170\u80fa\u4e09\u916f\u5408\u6210\u6cd5\u3001\u5149\u5316\u5b66\u8131\u4fdd\u62a4\u5408\u6210\u6cd5\u3001\u7535\u5316\u5b66\u5408\u6210\u6cd5\u3001\u6c22\u78f7\u9178\u916f\u5408\u6210\u6cd5\u3001\u4e24\u6b65\u5408\u6210\u6cd5\u3001\u53cc\u78b1\u57fa\u5355\u4f53\u5408\u6210\u6cd5\u7b49\uff0c\u5177\u4f53\u89c1\u300aDNA\u5b58\u50a8\u84dd\u76ae\u4e66\u300b\u3002<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwHK7ZicvPEXrsnBnQ8ZcLpoyGkyQBpY2VMuIKxVEybW8HLTqibIok892Q.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwHK7ZicvPEXrsnBnQ8ZcLpoyGkyQBpY2VMuIKxVEybW8HLTqibIok892Q\"\/><\/figure><\/div>\n\n<div>\u56fd\u5916\u5de5\u4e1a\u5316\u7684Oligo\u5408\u6210\u5b9a\u5236\u670d\u52a1\uff0c\u59cb\u4e8e1989\u5e74\u7531ABI\u63a8\u51fa\u7684\u7b2c\u4e00\u53f0\u5546\u4e1a\u5316\u81ea\u52a8DNA\u5408\u6210\u4eea\u3002\u56fd\u5185\u59cb\u4e8e1995\u5e74\u7531\u751f\u5de5\u751f\u7269\u5efa\u6210\u7b2c\u4e00\u6761\u5546\u7528Oligo\u5408\u6210\u751f\u4ea7\u7ebf\uff0c\u6807\u5fd7\u7740\u4e2d\u56fd\u7531\u6b64\u5f00\u59cb\u4e86DNA\u5408\u6210\u5b9a\u5236\u5316\u670d\u52a1\u7684\u5927\u89c4\u6a21\u5e94\u7528\u3002<\/div>\n<div>\u00a0<\/div>\n<div>Oligo\u5408\u6210\u9700\u8981\u5728\u5408\u6210\u4eea\u7684\u5408\u6210\u67f1\u4e0a\u5148\u5f97\u5230Oligo\u7c97\u54c1\uff0c\u518d\u7ecf\u8fc7\u6c28\u89e3\u3001\u7eaf\u5316\u3001\u5b9a\u91cf\u3001\u5206\u88c5\u548c\u5e72\u71e5\u7b49\u6b65\u9aa4\uff0c\u6700\u7ec8\u83b7\u5f97\u7b26\u5408\u5ba2\u6237\u5b9a\u5236\u9700\u6c42\u7684Oligo\u6210\u54c1\u3002\u4ece\u5408\u6210\u7684\u57fa\u672c\u6280\u672f\u539f\u7406\u4e0a\u6765\u8bf4\uff0c\u201c\u4e9a\u78f7\u9170\u80fa\u4e09\u916f\u6cd5\u201d\u4ecd\u662f\u76ee\u524d\u4e3b\u6d41\u7684Oligo\u5316\u5b66\u5408\u6210\u7684\u539f\u7406\u57fa\u7840\u3002\u800c\u4ece\u8bbe\u5907\u5e73\u53f0\u4e0a\uff0c\u6839\u636e\u4e0d\u540c\u7684\u5e94\u7528\u573a\u666f\uff0c \u53ef\u5177\u4f53\u53ef\u5206\u4e3a\u4e09\u4e2a\u4e0d\u540c\u7684\u5c42\u9762\uff1a<\/div>\n<ul>\n<li>\u67f1\u5f0f\u6cd5\u56fa\u76f8\u5408\u6210\u548c\u82af\u7247\u5408\u6210<\/li>\n<li>\u8d85\u5fae\u91cf\u3001\u5fae\u91cf\u3001\u5e38\u89c4\u91cf\u548c\u5927\u89c4\u6a21\u5408\u6210<\/li>\n<li>\u4f4e\u901a\u91cf\u3001\u4e2d\u901a\u91cf\u548c\u9ad8\u901a\u91cf\u5408\u6210<\/li>\n<\/ul>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwLXmeTicnPNK6hDG0j4QW0j1zyRF2a3Tt7vaJyCyPyPPD2FjlrCiaQC4A.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwLXmeTicnPNK6hDG0j4QW0j1zyRF2a3Tt7vaJyCyPyPPD2FjlrCiaQC4A\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>DNA\u5408\u6210\u4eea\u662fDNA\u5408\u6210\u7684\u6838\u5fc3\u88c5\u5907\u3002\u81ea\u4e0a\u4e16\u7eaa\u4e5d\u5341\u5e74\u4ee3\u8d77\uff0c\u82f1\u7f8e\u7b49\u56fd\u57fa\u4e8e\u7ecf\u5178\u5316\u5b66\u5408\u6210\u6cd5\u539f\u7406\u57fa\u7840\u4e0a\u5f00\u59cb\u4e86DNA\u5408\u6210\u4eea\u7684\u7814\u53d1\u4e0e\u5546\u4e1a\u5316\uff0c\u7ecf\u5386\u4e86\u4ece\u7b2c\u4e00\u4ee3\u67f1\u5f0f\u5408\u6210\u4eea\u5230\u7b2c\u4e8c\u4ee3\u9ad8\u901a\u91cf\u82af\u7247\u5408\u6210\u4eea\u7684\u5173\u4e24\u4e2a\u5173\u952e\u6027\u65f6\u671f\u3002\u76ee\u524d\uff0c\u7b2c\u4e00\u4ee3\u67f1\u5f0f\u5408\u6210\u4eea\u5728\u5e02\u573a\u4e0a\u6709\u591a\u6b3e\u673a\u578b\u6d41\u901a\uff0c\u5176\u4e2d\u63a5\u53d7\u5ea6\u8f83\u9ad8\u7684\u4ee3\u8868\u662fBioautomation-Mermade\u548cBiolyitc-Dr.Oligo\u7cfb\u5217\u5408\u6210\u4eea\u3002\u8be6\u60c5\u89c1\u300aDNA\u5b58\u50a8\u84dd\u76ae\u4e66\u300b\u4ecb\u7ecd\u3002<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwRDr2iapHCjUPJUokSVS6qabcdNf3mrqicOx5xdrg9af5VftWdicLiaJYXg.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwRDr2iapHCjUPJUokSVS6qabcdNf3mrqicOx5xdrg9af5VftWdicLiaJYXg\"\/><\/figure><\/div>\n\n<\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwxKmcjmsISye4oyVm9iazwSItQTJEiaCL9vvSprjYibKQZR80akMWuy86A.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwxKmcjmsISye4oyVm9iazwSItQTJEiaCL9vvSprjYibKQZR80akMWuy86A\"\/><\/figure><\/div>\n\n<div>\u76f8\u6bd4\u4e00\u4ee3\u67f1\u5f0f\u5408\u6210\u4eea\uff0c\u4e8c\u4ee3\u9ad8\u901a\u91cf\u82af\u7247\u5408\u6210\u4eea\u7684\u901a\u91cf\u9ad8\u3001\u6210\u672c\u4f4e\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u82af\u7247\u5408\u6210\u4eea\uff0c\u5373\u4ee5\u82af\u7247\u4e3aDNA\u5408\u6210\u8f7d\u4f53\u3002\u5355\u5f20\u82af\u7247\u53ef\u5b9e\u73b0\u6210\u5343\u4e0a\u4e07\u6761\u957f\u5ea6\u4e0d\u7b49\u7684\u5355\u94feDNA\u5408\u6210\u3002\u8be5\u7c7b\u578b\u8bbe\u5907\u53ef\u5728\u63d0\u4f9b\u9ad8\u901a\u91cf\u5408\u6210\u7684\u540c\u65f6\u964d\u4f4e\u8bd5\u5242\u7684\u6d88\u8017\uff0c\u521d\u6b65\u5b9e\u73b0\u4f4e\u6210\u672c\u9ad8\u901a\u91cf\u7684\u5be1\u6838\u82f7\u9178\u5408\u6210\u3002\u4f46\u76ee\u524d\u5e02\u573a\u4e0a\u4ec5\u63d0\u4f9b\u6280\u672f\u670d\u52a1\uff0c\u8fd8\u6ca1\u6709\u5546\u4e1a\u5316\u7684\u4eea\u5668\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u76ee\u524d\u56fd\u9645\u4e0a\u7684\u9ad8\u901a\u91cf\u5408\u6210\u4eea\uff0c\u6839\u636e\u5176\u5408\u6210\u539f\u7406\u4e3b\u8981\u5305\u62ec\u4e94\u7c7b\uff1a<\/div>\n<div>\u5149\u5316\u5b66\u6cd5DNA\u5408\u6210\u4eea\uff1a\u4ee5\u8054\u5ddd\u751f\u7269\u4e3a\u4ee3\u8868\u673a\u6784\uff0c\u4ee3\u8868\u4eea\u5668\u53ef\u4ee5\u57282.5cm*4cm\u5927\u5c0f\u7684\u82af\u7247\u4e0a\u4e00\u6b21\u6027\u5408\u6210\u6570\u4e07\u6761DNA\uff0c\u5408\u6210DNA\u957f\u5ea6\u8fbe\u5230200nt\uff0c\u5747\u4e00\u6027\u826f\u597d;\u5728\u8f7d\u73bb\u7247\u5927\u5c0f\u7684\u57fa\u8d28\u4e0a\u540c\u65f6\u5408\u6210\u6570\u5341\u4e07\u6761DNA\u3002<\/div>\n<div>\u7535\u5316\u5b66\u6cd5DNA\u5408\u6210\u4eea\uff1a\u4ee5Custom Array\u4e3a\u4ee3\u8868\u673a\u6784\uff0c\u57fa\u4e8e\u7535\u5316\u5b66\u539f\u7406\u7684\u9ad8\u901a\u91cfDNA\u5408\u6210\u4eea\u662f\u76ee\u524d\u552f\u4e00\u88ab\u5546\u4e1a\u5316\u7684\u9ad8\u901a\u91cf\u82af\u7247DNA\u5408\u6210\u4eea\u3002\u5408\u6210\u53cd\u5e94\u5df2\u7f29\u5c0f\u5230\u5fae\u7c73\u7ea7\u522b\u7684\u53cd\u5e94\u5b54\u5185\uff0c\u4e00\u5f20\u82af\u7247\u7684\u5408\u6210\u6c60\u4e0a\u6709\u4e0a\u4e07\u4e2a\u53cd\u5e94\u5b54\u3002<\/div>\n<div>\u55b7\u58a8\u6253\u5370\u6cd5DNA\u5408\u6210\u4eea\uff1a\u4ee5Agilent\u3001Twist Bioscience\u3001\u8fea\u8d62\u751f\u7269\u4e3a\u4ee3\u8868\u673a\u6784\u3002\u5176\u4e2d\uff0cAgilent\u516c\u53f8\u6700\u65e9\u5b9e\u73b0\u5229\u7528\u55b7\u58a8\u6253\u5370\u539f\u7406\u8fdb\u884cDNA\u5408\u6210\uff0c\u968f\u540e\uff0cTwist Bioscience\u516c\u53f8\u8fdb\u4e00\u6b65\u6539\u8fdb\u4e86\u5408\u6210\u82af\u7247\u8bbe\u8ba1\uff0c\u5e76\u5f00\u53d1\u4e86\u9ad8\u901a\u91cfDNA\u5408\u6210\u4eea\u3002<\/div>\n<div>\u57fa\u4e8e\u96c6\u6210\u7535\u8def\u63a7\u5236\u539f\u7406\u7684DNA\u5408\u6210\u4eea\uff1a\u4ee5Evonetix\u516c\u53f8\u4e3a\u4ee3\u8868\u673a\u6784\uff0c\u5173\u952e\u6280\u672f\u662f\u7406\u8bba\u4e0a\u63a5\u8fd1\u5341\u4ebf\u4e2a\u4f4d\u70b9\u7684Oligo\u5408\u6210\u548c\u53ef\u5b9e\u65f6\u76d1\u6d4b\u7684\u9ad8\u4fdd\u771fDNA\u7ea0\u9519\u7ec4\u88c5\u6280\u672f\u3002\u8be5\u6280\u672f\u8fd8\u5904\u4e8e\u7814\u53d1\u548c\u672a\u516c\u5f00\u9636\u6bb5\uff0c\u5b9e\u9645\u5e94\u7528\u6548\u679c\u8fd8\u6709\u5f85\u9a8c\u8bc1\u3002<\/div>\n<div>\u57fa\u4e8e\u5206\u9009\u7684\u9ad8\u901a\u91cf\u5e76\u884c\u5408\u6210\u539f\u7406\u7684DNA\u5408\u6210\u4eea\uff1a\u4ee5\u6df1\u5733\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u4e3a\u4ee3\u8868\u673a\u6784\uff0c\u65d7\u4e0b\u57fa\u4e8e\u5206\u9009\u7684\u9ad8\u901a\u91cf\u5e76\u884c\u5408\u6210\u539f\u7406\u81ea\u4e3b\u7814\u5236DNA\u5408\u6210\u4eea\uff0c\u76ee\u524d\u6700\u9ad8\u901a\u91cf\u8fbe\u5341\u4e07\u7ea7\uff0c\u5728\u9519\u8bef\u7387\uff08~1\u2030 -3\u2030\uff09\u53ca\u5408\u6210\u8f7d\u91cf\uff08&gt; pmol \u7ea7\u522b\uff09\u65b9\u9762\u5177\u5907\u7a81\u51fa\u4f18\u52bf\uff0c \u6709\u671b\u5feb\u901f\u5b9e\u73b0\u5408\u6210\u6210\u672c\u7684\u6307\u6570\u7ea7\u4e0b\u964d\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u5316\u5b66\u5408\u6210\u6280\u672f\u9762\u4e34\u7684\u884c\u4e1a\u75db\u70b9\uff08\u89e3\u51b3\u65b9\u6848\u89c1\u84dd\u76ae\u4e66\uff09\uff1a<\/div>\n<div>Oligo\u5408\u6210\u7684\u957f\u5ea6\u8d8a\u957f\u96be\u5ea6\u8d8a\u9ad8<\/div>\n<div>\u4e0d\u540c\u5e94\u7528\u5e02\u573a\u5bf9Oligo\u7684\u591a\u6837\u5316\u5b9a\u5236\u9700\u6c42<\/div>\n<div>\u5728\u9ad8\u901a\u91cf\u5408\u6210\u548c\u5927\u89c4\u6a21\u5408\u6210\u4e0a\u627e\u5bfb\u5e73\u8861\u70b9<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwvhXas8BSW8JyzQBmOGajYdQWd3Q5Wb5HnLSQaCYOrInzHIU9oicr3eQ.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwvhXas8BSW8JyzQBmOGajYdQWd3Q5Wb5HnLSQaCYOrInzHIU9oicr3eQ\"\/><\/figure><\/div>\n\n<div>\u9176\u4fc3\u5408\u6210\uff1a\u4f20\u7edf\u4e9a\u78f7\u9170\u80fa\u5316\u5b66\u5408\u6210\u6cd5\u53d7\u5316\u5b66\u53cd\u5e94\u6548\u7387\u9650\u5236\uff0cDNA\u5408\u6210\u4ea7\u7269\u957f\u5ea6\u4ec5\u80fd\u8fbe\u5230\u7ea6200-250nt\uff0c\u6781\u5927\u5730\u9650\u5236\u4e86\u4e0b\u6e38\u5e94\u7528\u3002\u5408\u6210\u8fc7\u7a0b\u4e2d\u6d89\u53ca\u5f3a\u9178\u3001\u5f3a\u6c27\u5316\u5242\uff0c\u4ea7\u751f\u8f83\u591a\u5bf9\u73af\u5883\u6709\u5bb3\u7684\u5316\u5b66\u5e9f\u6db2\uff0c\u5bfc\u81f4\u540e\u7eed\u5904\u7406\u8d39\u7528\u9ad8\u6602\u3002\u800c\u8fd1\u51e0\u5e74\u51fa\u73b0\u7684\u751f\u7269\u9176\u6cd5DNA\u5408\u6210\u6280\u672f\u901a\u5e38\u5728\u6c34\u76f8\u73af\u5883\u4e0b\u8fdb\u884c\uff0c\u53ef\u6709\u6548\u907f\u514d\u4e0a\u8ff0\u95ee\u9898\uff0c\u5e76\u6709\u671b\u4ee5\u66f4\u4f4e\u7684\u6210\u672c\u5408\u6210\u66f4\u957f\u7684DNA\u5206\u5b50\u3002\u5728\u81ea\u7136\u754c\u4e2d\uff0cDNA\u5206\u5b50\u7684\u4f53\u5185\u5408\u6210\u4e3b\u8981\u662f\u7531\u5404\u79cdDNA\u805a\u5408\u9176\u50ac\u5316\u5e76\u4f9d\u8d56\u4e8eDNA\u6a21\u677f\u8fdb\u884c\u5408\u6210\u3002DNA\u672b\u7aef\u8f6c\u79fb\u9176\u548c\u4e00\u4e9b\u79cd\u7c7b\u7684DNA\u805a\u5408\u9176\u5374\u53ef\u4ee5\u4e0d\u4f9d\u8d56\u4e8e\u5df2\u6709\u7684DNA\u6a21\u677f\u5206\u5b50\uff0c\u76f4\u63a5\u50ac\u5316DNA\u94fe\u7684\u5408\u6210\u3002\u800c\u751f\u7269\u9176\u6cd5DNA\u5408\u6210\u6280\u672f\u4e5f\u501f\u9274\u4e86\u81ea\u7136\u754c\u4e2d\u7684\u4e0d\u540cDNA\u5408\u6210\u65b9\u5f0f\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u9176\u4fc3\u5408\u6210\u6280\u672f\u4e3e\u4f8b\uff08\u8be6\u60c5\u89c1\u300aDNA\u5b58\u50a8\u84dd\u76ae\u4e66\u300b\uff09\uff1a<\/div>\n<div>TdT\u9176\u4ecb\u5bfc\u7684\u9176\u4fc3\u5408\u6210\u53cd\u5e94<\/div>\n<div>TdT-dNTP\u4ea4\u8054\u4f53\u4ecb\u5bfc\u7684\u9176\u4fc3\u5408\u6210\u53cd\u5e94<\/div>\n<div>\u6df7\u5408\u9176\u4ecb\u5bfc\u7684\u9176\u4fc3\u53cd\u5e94<\/div>\n<div>\u8fde\u63a5\u5408\u6210\uff1a\u7531\u4e8eDNA\u5b58\u50a8\u76ee\u524d\u901a\u5e38\u91c7\u7528\u6309\u9700\u5408\u6210\uff0c\u5373\u6bcf\u6b21\u9700\u5b58\u50a8\u7684\u6570\u636e\u5728\u8fdb\u884c\u201c\u6bd4\u7279-\u78b1\u57fa\u201d\u7f16\u7801\u8f6c\u6362\u540e\uff0c \u5c06\u5f97\u5230\u7684DNA\u5e8f\u5217\u4ee5\u5be1\u6838\u82f7\u9178\u6587\u5e93\u6216DNA\u7247\u6bb5\u5f62\u5f0f\u4ece\u5934\u5408\u6210\u3002\u800c\u5728\u9488\u5bf9\u5927\u91cf\u6570\u636e\u7684\u5b58\u50a8\u9700\u6c42\u65b9\u9762\uff0c\u73b0\u9636\u6bb5\u8be5\u65b9\u5f0f\u9700\u8981\u6295\u5165\u7684\u5408\u6210\u6210\u672c\u6781\u9ad8\u3002\u56e0\u6b64\uff0c\u4e0d\u5c11\u7814\u7a76\u8005\u6216\u4f01\u4e1a\u4e5f\u63d0\u51fa\u4e86\u9884\u5148\u5408\u6210\u77edDNA\u5e8f\u5217\u5355\u5143\uff0c\u5728\u4fe1\u606f\u5b58\u50a8\u65f6\u5c06\u77ed\u5e8f\u5217\u5355\u5143\u8fdb\u884c\u5b9a\u4f4d\u9009\u62e9\uff0c\u5e76\u6309\u987a\u5e8f\u8fde\u63a5\u8d77\u6765\u7684\u4fe1\u606f\u5199\u5165\uff08\u5408\u6210\uff09\u65b9\u5f0f\uff0c\u5373\u8fde\u63a5\u5408\u6210\u3002<\/div>\n<div>\u8fde\u63a5\u5408\u6210\u4ee3\u8868\u673a\u6784\u5305\u62ec\uff1a\u6df1\u5733\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u3001\u7f8e\u56fdCatalog\u516c\u53f8\u3001\u4e2d\u79d1\u9662\u6b66\u6c49\u75c5\u6bd2\u6240\u5218\u7fdf\u56e2\u961f\u7b49\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u56db\u3001DNA\u5b58\u50a8\u7b2c\u4e09\u6b65\uff1aDNA\u5c01\u88c5<\/div>\n<div>DNA\u5206\u5b50\u7684\u4fdd\u5b58\u662fDNA\u5b58\u50a8\u4e2d\u7684\u91cd\u8981\u73af\u8282\uff0c\u5c3d\u7ba1DNA\u5206\u5b50\u751f\u5316\u7a33\u5b9a\u6027\u9ad8\uff0c\u5176\u534a\u8870\u671f\u53ef\u957f\u8fbe521\u5e74\uff0c\u4f46\u66b4\u9732\u5728\u7a7a\u6c14\u4e2d\u7684DNA\u6781\u6613\u88abDNA\u9176\u964d\u89e3\u3002\u5728\u957f\u671f\u4fdd\u5b58\u4e2d\uff0cDNA\u5206\u5b50\u4e5f\u53ef\u80fd\u53d1\u751f\u5316\u5b66\u952e\u7684\u65ad\u88c2\u3001 \u78b1\u57fa\u7684\u7a81\u53d8\uff08\u5982\u8131\u560c\u5464\uff09\u7b49\u635f\u4f24\uff0c\u56e0\u6b64\u968f\u7740\u5206\u5b50\u94fe\u7684\u957f\u5ea6\u589e\u52a0\uff0c\u5176\u534a\u8870\u671f\u4e5f\u663e\u8457\u964d\u4f4e\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u4ece\u5c01\u88c5\u7684\u5f62\u5f0f\u4e0a\uff0c\u53ef\u5206\u4e3a\u7269\u7406\u5c01\u88c5\uff08\u5373\u901a\u8fc7\u4f4e\u6e29\u5bc6\u5c01\u3001\u77ff\u5316\u3001\u65e0\u673a\u7269\u5bc6\u5c01\u3001\u56fa\u4f53\u80f6\u56ca\u7b49\u5f62\u5f0f\u8fdb\u884c\u5c01\u88c5\uff09\u548c\u751f\u7269\u5c01\u88c5\uff08\u5373\u5c06 DNA \u5206\u5b50\u901a\u8fc7\u4e0d\u540c\u5f62\u5f0f\u5b58\u50a8\u5728\u6d3b\u7ec6\u80de\u5185\uff0c\u5e76\u8fdb\u884c\u4f20\u4ee3\u6216\u4f4e\u6e29\u4fdd\u5b58\uff09\u4e24\u79cd\u3002<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbw59IeKhBCj16bwwAXD5QGyVm3WVAecyBsHW1OWWwlvouhHuw3H1SnZQ.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbw59IeKhBCj16bwwAXD5QGyVm3WVAecyBsHW1OWWwlvouhHuw3H1SnZQ\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>\u9664\u4e86\u4f20\u7edf\u65b9\u5f0f\uff0c\u76f4\u63a5\u5c06\u643a\u5e26\u4fe1\u606f\u7684DNA\u7247\u6bb5\u901a\u8fc7\u57fa\u56e0\u7f16\u8f91\u7684\u65b9\u5f0f\u63d2\u5165\u6d3b\u7ec6\u80de\u7684\u57fa\u56e0\u7ec4\u5185\u4e5f\u662f\u4e00\u79cd\u53ef\u884c\u7684\u6280\u672f\u624b\u6bb5\u30022017\u5e74\u7f8e\u56fd\u54c8\u4f5b\u5927\u5b66\u7814\u7a76\u56e2\u961f\u5229\u7528\u76f4\u63a5\u57fa\u56e0\u7f16\u8f91\u7684\u65b9\u5f0f\uff0c\u5c06\u56fe\u7247\u548c\u77ed\u89c6\u9891\u901a\u8fc7DNA\u5b58\u50a8\u7684\u65b9\u5f0f\u5b58\u5165\u4e86\u5927\u80a0\u6746\u83cc\uff0c\u5e76\u6210\u529f\u5c06\u5176\u8bfb\u53d6\u6062\u590d\u3002\u5176\u6b65\u9aa4\u4e0e\u5e38\u89c4\u57fa\u56e0\u7f16\u8f91\u624b\u6bb5\u7c7b\u4f3c\uff0c\u5373\u5229\u7528CRISPR Cas\u7cfb\u7edf\u5c06\u591a\u4e2a\u5916\u6e90DNA\u5e8f\u5217\u63d2\u5165\u5927\u80a0\u6746\u83cc\u7684\u57fa\u56e0\u7ec4\u4e2d\u7684repeater\u533a\u57df\u3002<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwpVAiaq7mbzGPAae4O161HJSyhjPpJy2PhkrITt4AamsaibybhM8fsiaog.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwpVAiaq7mbzGPAae4O161HJSyhjPpJy2PhkrITt4AamsaibybhM8fsiaog\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>\u66f4\u6709\u610f\u601d\u7684\u662f\uff0c2021\u5e74\uff0c\u7f8e\u56fd\u54e5\u4f26\u6bd4\u4e9a\u5927\u5b66\u7814\u7a76\u56e2\u961f\u5229\u7528CRISPR Cas\u7cfb\u7edf\u5728\u7535\u538b\u4e0d\u540c\u60c5\u51b5\u4e0b\u8868\u73b0\u7684\u7279\u5f02\u6027\uff0c\u5c06\u7535\u4fe1\u53f7\u8109\u51b2\u5199\u5165\u7ec6\u83cc\u8d28\u7c92\u4e2d\uff0c\u5b9e\u73b0\u4e86\u7535\u5b66\u4fe1\u53f7\u5411\u751f\u7269\u4fe1\u53f7\u7684\u8f6c\u6362\uff0c\u4ece\u800c\u53ef\u4ee5\u901a\u8fc7\u4e8c\u8fdb\u5236\u7684\u65b9\u5f0f\u76f4\u63a5\u5728\u7ec6\u83cc\u8d28\u7c92\u4e2d\u5199\u5165\u4fe1\u606f\u3002<\/div>\n<div><\/div>\n<div>\u5728\u300a\u201c\u5341\u56db\u4e94\u201d\u56fd\u5bb6\u91cd\u70b9\u7814\u53d1\u8ba1\u5212\u201c\u751f\u7269\u4e0e\u4fe1\u606f\u878d\uff08BT \u4e0e IT \u878d\u5408 )\u201d\u91cd\u70b9\u4e13\u98792021\u5e74\u5ea6\u9879\u76ee\u7533\u62a5\u6307\u5357\u300b\u7684\u76f8\u5173\u9879\u76ee\u5305\u62ec\uff1a\u25cf DNA\u5206\u5b50\u4fe1\u606f\u5b58\u50a8\u7684\u9ad8\u52a0\u5bc6\u6027\u7f16\u7801\u4e0e\u4fe1\u606f\u5b89\u5168\u4f53\u7cfb\u7814\u7a76 \u25cf \u57fa\u4e8e\u591a\u7c7b\u578b\u751f\u7269\u5206\u5b50\u7684\u8d85\u9ad8\u5bc6\u5ea6\u4fe1\u606f\u5b58\u50a8\u6280\u672f\u7814\u53d1 \u25cf \u5927\u89c4\u6a21\u53ef\u5bfb\u5740\u53ef\u63a7\u50ac\u5316DNA\u5408\u6210\u6280\u672f\u7814\u53d1 \u25cf \u8d85\u9ad8\u901a\u91cf\u5355\u5206\u5b50\u6676\u4f53\u7ba1\u6d4b\u5e8f\u6280\u672f\u7814\u53d1<\/div>\n<div><\/div>\n<div><\/div>\n<div>\u4e94\u3001DNA\u5b58\u50a8\u7b2c\u56db\u6b65\uff1aDNA\u6d4b\u5e8f<\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwDdsH1bKYh67GPphsRwLeO36a8NbmbfcRhKhWuqKiasH1yWSwM3sog5g.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwDdsH1bKYh67GPphsRwLeO36a8NbmbfcRhKhWuqKiasH1yWSwM3sog5g\"\/><\/figure><\/div>\n\n<div>DNA\u6d4b\u5e8f\u662f\u6307\uff0c\u5229\u7528\u57fa\u56e0\u6d4b\u5e8f\u6280\u672f\u83b7\u5f97\u76ee\u6807DNA\u7247\u6bb5\u7684\u78b1\u57fa\u6392\u5217\u987a\u5e8f\uff0c\u5373\u817a\u560c\u5464A\u3001\u80f8\u817a\u5627\u5576T\u3001\u80de\u5627\u5576C\u3001\u9e1f\u560c\u5464G\u7684\u6392\u5217\u987a\u5e8f\u3002\u800cDNA\u5b58\u50a8\u7684\u539f\u7406\u672c\u8d28\u4e0a\u662f\u5c06\u6570\u5b57\u6587\u4ef6\u7684\u4e8c\u8fdb\u5236\u7f16\u7801\uff080\u30011) \u8f6c\u6362\u4e3aDNA\u78b1\u57fa\u7684\u56db\u8fdb\u5236\u7f16\u7801\uff08A\u3001T\u3001C\u3001G)\u5e76\u901a\u8fc7DNA\u5408\u6210\u5b8c\u6210\u4fe1\u606f\u5199\u5165\u3002\u56e0\u6b64\uff0c\u5c06\u5b58\u50a8\u5728DNA\u7247\u6bb5\u4e2d\u7684\u4fe1\u606f\u8bfb\u51fa\uff0c\u9996\u5148\u9700\u8981\u6d4b\u5b9a\u8be5DNA\u7247\u6bb5\u7684\u78b1\u57fa\u5e8f\u5217\uff0c\u5373DNA\u6d4b\u5e8f\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u4ece1975\u5e74Frederick Sanger\u53d1\u660e\u7684Sanger\u53cc\u8131\u6c27\u94fe\u7ec8\u6b62\u6cd5\u81f3\u4eca\uff0c\u6d4b\u5e8f\u6280\u672f\u7ecf\u5386\u4e86\u8fd150\u5e74\u7684\u53d1\u5c55\u3002\u4ece\u521d\u6b65\u89c4\u6a21\u5316\u5230\u5f53\u4eca\u4e3b\u6d41\u7684\u5927\u89c4\u6a21\u5e73\u884c\u6d4b\u5e8f\uff08Massively Parallel Sequencing, MPS\u4ec5\u7528\u4e86\u77ed\u77ed\u7684\u5341\u4f59\u5e74\uff0c\u5305\u62ec\u4f46\u4e0d\u9650\u4e8e:<\/div>\n<ul>\n<li>\u7126\u78f7\u9178\u6d4b\u5e8f\u6cd5\uff08454\u7cfb\u5217\u6d4b\u5e8f\u4eea\uff0c\u540e\u4e8e2007\u5e74\u88ab\u7f57\u6c0f\u6536\u8d2d\uff0c\u5e76\u4e8e2014\u5e74\u505c\u4ea7\uff09<\/li>\n<li>\u534a\u5bfc\u4f53\u6d4b\u5e8f\u6cd5\uff08Ion Torrent\u7cfb\u5217\u6d4b\u5e8f\u4eea\uff0c\u540e\u4e8e2013\u5e74\u88abThermo Fisher\u6536\u8d2d\uff09<\/li>\n<li>\u53ef\u9006\u672b\u7aef\u7ec8\u6b62\u6d4b\u5e8f\u6cd5\uff08\u4ee5Solexa\u6d4b\u5e8f\u6280\u672f\u4e3a\u57fa\u7840\u7684Illumina\u6d4b\u5e8f\u4eea\uff09<\/li>\n<li>\u8054\u5408\u63a2\u9488\u951a\u5b9a\u805a\u5408\u6d4b\u5e8f\u6cd5\uff08\u4ee5DNBSEQ\u6d4b\u5e8f\u6280\u672f\u4e3a\u6838\u5fc3\u7684\u534e\u5927\u667a\u9020\u6d4b\u5e8f\u4eea\uff09&#8230;&#8230;<\/li>\n<\/ul>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwrPlZoJIscZFCXicvN72EQ1I5QdXy97KukEM3PJ9coneHdFOoLDJvPOw.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwrPlZoJIscZFCXicvN72EQ1I5QdXy97KukEM3PJ9coneHdFOoLDJvPOw\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>\u6d4b\u5e8f\u6280\u672f\u8bc4\u4ef7\uff1a\u4f5c\u4e3aDNA\u5b58\u50a8\u7684\u5173\u952e\u73af\u8282\u4e4b\u4e00\uff0c\u6d4b\u5e8f\u6280\u672f\u7684\u53d1\u5c55\u4e3aDNA\u5b58\u50a8\u7684\u53ef\u884c\u6027\u548c\u666e\u53ca\u6027\u521b\u9020\u4e86\u65b9\u4fbf\u5feb\u6377\u7684\u6761\u4ef6\u548c\u8def\u5f84\u9009\u62e9\u3002\u4f46\u662f\uff0c\u4e0d\u53ef\u5426\u8ba4\u7684\u662f\uff0c\u76ee\u524d\u5728\u6d4b\u5e8f\u8fc7\u7a0b\u4e2d\u4e5f\u4f1a\u5b58\u5728\u4e00\u5b9a\u7684\u5931\u771f\u60c5\u51b5\uff0c\u8fd9\u4f1a\u5bf9\u8fd8\u539fDNA\u5b58\u50a8\u4fe1\u606f\u5e26\u6765\u201c\u566a\u58f0\u201d\u3002<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCT5woUryHtpe92DbyBLYbwZO5oZibOUXdDCy3xLWLibM3e2Qcd2ibiasT9RSicwbPhiaich9micjWOxTIWLw.png\" alt=\"RmFicvQBAkgCT5woUryHtpe92DbyBLYbwZO5oZibOUXdDCy3xLWLibM3e2Qcd2ibiasT9RSicwbPhiaich9micjWOxTIWLw\"\/><\/figure><\/div>\n\n<div>\u6e05\u534e\u5927\u5b66\u7814\u7a76\u56e2\u961f\u5efa\u7acb\u4e86\u9488\u5bf9\u78b1\u57fa\u7a81\u53d8\u3001\u5e8f\u5217\u4e22\u5931\u7b49\u4e0d\u540c\u7c7b\u578bDNA\u5b58\u50a8\u4fe1\u9053\u566a\u58f0\u4eff\u771f\u7b97\u6cd5\uff0c \u5e76\u57fa\u4e8e\u566a\u58f0\u5206\u5e03\u4eff\u771f\u8fdb\u884c\u4e86\u7f16\u7801\u7b97\u6cd5\u4f18\u5316\uff1a\u5229\u7528iGeneTech\u82af\u7247\u9ad8\u901a\u91cf\u5408\u6210~1\u4e07\u6761DNA\u5e8f\u5217\u3001PCR\u6269\u589e\uff0c\u7136\u540e\u5bf9\u8be5\u5e8f\u5217\u8fdb\u884c\u9ad8\u901a\u91cf\u6d4b\u5e8f\uff0c\u5c06\u6d4b\u5e8f\u540ereads\u7684\u94fe\u5185\u566a\u58f0\u3001\u94fe\u95f4\u566a\u58f0\u7684\u7edf\u8ba1\u7ed3\u679c\u4e0e\u4eff\u771f\u7b97\u6cd5\u6bd4\u8f83\uff0c\u6700\u7ec8DNA\u5e8f\u5217\u4e22\u5931\u4e0e\u94fe\u5185\u9519\u8bef\u7684\u566a\u58f0\u4eff\u771f\u7ed3\u679c\uff0c\u4e0e\u5b9e\u9645\u9ad8\u901a\u91cf\u6587\u5e93\u5408\u6210\u3001PCR\u540e\uff0c\u9ad8\u901a\u91cf\u6d4b\u5e8f\u7684\u7edf\u8ba1\u7ed3\u679c\u4e00\u81f4\u3002<\/div>\n<div>\u5728\u5177\u4f53\u7684\u6d4b\u5e8f\u8fc7\u7a0b\u4e2d\u8fd8\u6d89\u53ca\u5230\u6587\u5e93\u6784\u5efa\u3002\u4f8b\u5982DNA\u6d4b\u5e8f\u524d\u7684\u83b7\u53d6\u6b65\u9aa4\u4e2d\uff08Random access\uff09\uff0c\u4f20\u7edfPCR\u6269\u589e\u5bf9\u539f\u59cbDNA\u6587\u5e93\u7834\u574f\u4e25\u91cd\uff0c\u4f7f\u5176\u96be\u4ee5\u91cd\u590d\u8bfb\u53d6\u3002\u56e0\u6b64\u901a\u8fc7\u6539\u8fdbPCR\u3001\u78c1\u73e0\u5206\u79bb\u7b49\u65b9\u6cd5\u5bf9DNA\u6587\u5e93\u4e2d\u7684\u6587\u4ef6\u9009\u62e9\u6027\u5730\u83b7\u53d6\u4e5f\u662f\u8fd1\u5e74\u6765\u7684\u7814\u7a76\u70ed\u70b9\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u672a\u6765\uff0cDNA\u5b58\u50a8\u6280\u672f\u5c06\u4f1a\u4e0e\u5305\u62ec\u6d4b\u5e8f\u6280\u672f\u5728\u5185\u7684\u5176\u4ed6DNA\u76f8\u5173\u7684\u6280\u672f\u8054\u7cfb\u66f4\u52a0\u7d27\u5bc6\u3002Grass\u7b49\u4eba\u4e8e2022\u5e74\u5728Nature Communications\u53d1\u8868\u7efc\u8ff0\uff0c\u8ba4\u4e3aDNA\u5b58\u50a8\u6280\u672f\u53ef\u4e0eDNA\u8ba1\u7b97\u3001DNA\u795e\u7ecf\u7f51\u7edc\u7ed3\u5408\uff0c\u5728\u4f20\u7edfDNA\u5b58\u50a8\u7cfb\u7edf\u4e2d\u5f15\u5165\u903b\u8f91\u5355\u5143\uff0c\u5b9e\u73b0\u66f4\u52a0\u667a\u80fd\u7684\u4fe1\u606f\u7ba1\u7406\u548c\u83b7\u53d6\u3002\u968f\u7740\u76f8\u5173\u7814\u7a76\u7684\u65e5\u76ca\u4e30\u5bcc\uff0c\u4ee5\u53ca\u6d4b\u5e8f\u6280\u672f\u7684\u6210\u719f\u53d1\u5c55\uff0cDNA\u5b58\u50a8\u6280\u672f\u53ca\u4ea7\u54c1\u5c06\u6210\u4e3a\u4e00\u9879\u4eba\u4eba\u53ef\u53ca\u3001\u4eba\u4eba\u666e\u60e0\u3001\u4eba\u4eba\u53ef\u9009\u7684\u5e38\u89c1\u5b58\u50a8\u65b9\u5f0f\u4e4b\u4e00\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u4f5c\u8005\u4e28\u76ee\u53c8\uff08\u57fa\u56e0\u6167\uff09\u00a0\u00a0<\/div>\n<div>\u7f16\u8f91\u4e28Barney<\/div>\n<div>\u5173\u952e\u8bcd | DNA\u5b58\u50a8<\/div>\n<div>\u00a0<\/div>\n<div>\u53c2\u8003\u8d44\u6599\uff1a<\/div>\n<div>[1] Extance, A. How DNA could store all the world\u2019s data. Nature 537, 22\u201324 (2016)<\/div>\n<div>[2] \u57fa\u56e0\u6167\u7b49\uff0cDNA\u5b58\u50a8\u84dd\u76ae\u4e66<\/div>\n<div>\u00a0<\/div>\n<div>\u5173\u4e8e\u300aDNA\u5b58\u50a8\u84dd\u76ae\u4e66\u300b<\/div>\n<div>\u53ca\u4e0b\u8f7d\u94fe\u63a5<\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCTuJGGU3FyLMiaypqnqOZynjFAzZf5f896EcpAhWb5K6axe6ULDPUWDnGTmdC6mMNc0lGpic188IpQ.jpeg\" alt=\"RmFicvQBAkgCTuJGGU3FyLMiaypqnqOZynjFAzZf5f896EcpAhWb5K6axe6ULDPUWDnGTmdC6mMNc0lGpic188IpQ\"\/><\/figure><\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCTuJGGU3FyLMiaypqnqOZyn6PzyAuhAyqfUpb5tW9zjfNrf05JSDCNyY8MNyBibW9nPBak0c4ubH0A.jpeg\" alt=\"RmFicvQBAkgCTuJGGU3FyLMiaypqnqOZyn6PzyAuhAyqfUpb5tW9zjfNrf05JSDCNyY8MNyBibW9nPBak0c4ubH0A\"\/><\/figure><\/div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCTuJGGU3FyLMiaypqnqOZynH1yx8wraz9b2YwKs42ia3EhWyzAVKmTS7SfAqr0kevRh26lXiaqUsNMA.png\" alt=\"RmFicvQBAkgCTuJGGU3FyLMiaypqnqOZynH1yx8wraz9b2YwKs42ia3EhWyzAVKmTS7SfAqr0kevRh26lXiaqUsNMA\"\/><\/figure><\/div>\n\n<div>\u4e0b\u8f7d\u94fe\u63a5<\/div>\n<div>\u626b\u7801\u767b\u8bb0<\/div>\n<div>\u5373\u53ef\u4e0b\u8f7d<\/div>\n<div>\u611f\u8c22\u6b27\u9633\u9880\u9662\u58eb\u3001\u5143\u82f1\u8fdb\u9662\u58eb\u3001\u6768\u7115\u660e\u9662\u58eb\u548c\u6a0a\u6625\u6d77\u9662\u58eb\u7684\u6307\u5bfc\u548c\u4f5c\u5e8f\uff0c\u611f\u8c22\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u3001\u534e\u5927\u667a\u9020\u3001\u56fd\u5bb6\u57fa\u56e0\u5e93\u53d1\u8d77\uff0c\u57fa\u56e0\u6167\u7b56\u5212\uff0c\u751f\u5de5\u751f\u7269\u3001\u8054\u5ddd\u751f\u7269\u3001\u64ce\u79d1\u751f\u7269\u3001\u817e\u8baf\u533b\u7597\u5065\u5eb7\u5bf9\u84dd\u76ae\u4e66\u7684\u5927\u529b\u652f\u6301\uff0c\u5171\u540c\u63a8\u52a8\u751f\u547d\u79d1\u6280\u666e\u60e0\u548c\u4ea7\u4e1a\u878d\u5408\u53d1\u5c55\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u3010\u9884\u544a\u3011\u57fa\u56e0\u6167\u7684\u300a2022\u57fa\u56e0\u884c\u4e1a\u84dd\u76ae\u4e66\u300b\u9884\u8ba1Q3\u53d1\u5e03\uff0c\u6b22\u8fce\u5730\u65b9\u653f\u5e9c\u548c\u884c\u4e1a\u5927\u4f1a\u5408\u4f5c\u53d1\u5e03\uff1b\u300a2023\u57fa\u56e0\u884c\u4e1a\u84dd\u76ae\u4e66\u300b\u5373\u5c06\u542f\u52a8\uff0c\u6b22\u8fce\u4f01\u4e1a\u9884\u7ea6\u8054\u5408\u53d1\u5e03\u9650\u91cf\u5408\u4f5c\u540d\u989d\u3002<\/div>\n<div>\u00a0<\/div>\n<div>\u6269\u5c55\u9605\u8bfb<\/div>\n<div><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247510463&amp;idx=1&amp;sn=d11a8107fbcb0043e1bd6b6a706ef483&amp;chksm=eb711b08dc06921e16498e95da853084ca941dd3f4035f51d3a92ababc27a8c348d5850d1d39&amp;scene=21#wechat_redirect\">\u56fd\u5185\u9996\u90e8DNA\u5b58\u50a8\u84dd\u76ae\u4e66\u53d1\u5e03\uff08\u9644\u4e0b\u8f7d\u94fe\u63a5\uff09<\/a><\/div>\n<div><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&amp;mid=2247510161&amp;idx=1&amp;sn=06d91569c9e2a3d9d27a83a3b3d9ae99&amp;chksm=eb711a26dc069330b52d534064489fb353d4df4cf96bc58f853264fb31972da8c83ea2cfeef4&amp;scene=21#wechat_redirect\">\u5143\u82f1\u8fdb\u9662\u58eb\uff1aDNA \u5b58\u50a8\u662f\u751f\u7269\u6280\u672f\u4e0e\u4fe1\u606f\u6280\u672f\u878d\u5408\u7684\u5178\u8303<\/a><\/div>\n<div><a 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