{"id":8759,"date":"2022-03-07T08:00:00","date_gmt":"2022-03-07T00:00:00","guid":{"rendered":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/03\/07\/10057100\/"},"modified":"2026-04-01T12:30:30","modified_gmt":"2026-04-01T04:30:30","slug":"10057100","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/03\/07\/10057100\/","title":{"rendered":"\u57fa\u56e0\u7b80\u62a5\uff08179\u671f\uff09\u4e28\u7f57\u6c0f\u79ef\u6781\u63a8\u8fdb\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u5e73\u53f0\u5f00\u53d1\uff1b\u771f\u6838\u7ec6\u80de\u4e2dCRISPR\u4e13\u5229\u82b1\u843d\u8c01\u5bb6\uff1f"},"content":{"rendered":"
\n
\"RmFicvQBAkgArd371ayccZ0h7b1kYMcLjfOJjqyYaicggtUOt4GZejHKvHdYRhPW7uQicuY0VUdyFt2hQoYekWYjA\"\/<\/figure><\/div>\n\n
\u4fe1\u606f\u901f\u89c8<\/div>\n
\u27762021\u5e74\u6211\u56fd\u5e73\u7a33\u53d1\u5c55\uff0c2022\u53d1\u5c55\u98ce\u5411\u5305\u62ec\u521b\u65b0\u836f\u3001\u5fae\u751f\u7269\u4e0e\u8111\u79d1\u5b66\u7814\u7a76\u7b49\u751f\u547d\u79d1\u5b66<\/div>\n
\u2777\u00a02022\u5e74\u201c\u5168\u7403\u5341\u5927\u7a81\u7834\u6027\u6280\u672f\u201d\u516c\u5e03\uff0c\u751f\u7269\u533b\u836f\u76f8\u5173\u6280\u672f\u5360\u56db\u5e2d<\/div>\n
\u2778\u4f20\u5947\u751f\u7269\u7684CAR-T\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u83b7FDA\u6279\u51c6\u4e0a\u5e02<\/div>\n
\u2779\u00a0\u827e\u514b\u4f26\u533b\u7597\u7684\u80ba\u764c\u8840\u6db2\u4e09\u57fa\u56e0\u7532\u57fa\u5316\u68c0\u6d4b\u8bd5\u5242\u76d2\u83b7NMPA\u6279\u51c6\u4e0a\u5e02<\/div>\n
\u277a\u00a0\u6211\u56fd\u51a0\u5fc3\u75c5\u591a\u57fa\u56e0\u98ce\u9669\u8bc4\u5206\u6a21\u578b\u53d1\u5e03<\/div>\n
\u277b\u00a0\u6e05\u534e\u5927\u5b66\u4e0e\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u5408\u4f5c\u5f00\u53d1\u5c0f\u578b\u3001\u9ad8\u6548CRISPR\u57fa\u56e0\u7f16\u8f91\u5de5\u5177<\/div>\n
\u277c\u00a0\u7f8e\u56fd\u4e13\u5229\u548c\u5546\u6807\u5c40\u5224\u5b9a\u5f20\u5cf0\u56e2\u961f\u62e5\u6709\u5728\u771f\u6838\u7ec6\u80de\u4e2d\u4f7f\u7528CRISPR\u7684\u4e13\u5229<\/div>\n
\u277d\u00a0\u7f57\u6c0f\u79ef\u6781\u62db\u8058\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u76f8\u5173\u804c\u4f4d\uff0c\u63a8\u8fdb\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u5f00\u53d1<\/div>\n
\u277e\u00a0\u6d4b\u5e8f\u8bbe\u5907\u7814\u53d1\u5546Singular\u4e0e\u7f57\u6c0f\u3001\u5b89\u6377\u4f26\u3001Qiagen\u8fbe\u6210\u5408\u4f5c\uff0c1\u6708\u5df2\u4e0e6\u5bb6\u516c\u53f8\u8fbe\u6210\u5408\u4f5c<\/div>\n
\u277f\u00a0\u4f53\u5916\u8bca\u65ad\u4f01\u4e1a\u83f2\u9e4f\u751f\u72693\u67083\u65e5\u521b\u4e1a\u677f\u9996\u53d1\u4e0a\u4f1a\u901a\u8fc7<\/div>\n
\u00a0<\/div>\n
\u5b8f\u89c2\u73af\u5883<\/div>\n
\u2756\u00a02021\u5e74\u6211\u56fd\u5e73\u7a33\u53d1\u5c55\uff0c2022\u53d1\u5c55\u98ce\u5411\u5305\u62ec\u521b\u65b0\u836f\u3001\u5fae\u751f\u7269\u4e0e\u8111\u79d1\u5b66\u7814\u7a76\u7b49\u751f\u547d\u79d1\u5b66<\/div>\n
2022\u5e743\u67085\u65e5\uff0c2021\u5e74\u653f\u5e9c\u5de5\u4f5c\u62a5\u544a\u6307\u51fa\uff0c\u6211\u56fd\u7edf\u7b79\u75ab\u60c5\u9632\u63a7\u548c\u793e\u4f1a\u7ecf\u6d4e\u53d1\u5c55\uff0c\u5168\u5e74\u76ee\u6807\u8f83\u597d\u5b8c\u6210\u30022022\u5e74\u6c11\u751f\u91cd\u70b9\u5de5\u4f5c\u4e2d\uff0c\u5305\u62ec\u6539\u9769\u75be\u75c5\u9884\u9632\u63a7\u5236\u4f53\u7cfb\u3001\u836f\u54c1\u75ab\u82d7\u76d1\u7ba1\u7b49\uff0c\u5b9e\u65bd\u79d1\u6280\u4f53\u5236\u6539\u9769\u4e09\u5e74\u653b\u575a\u65b9\u6848\u3002\u6b64\u5916\uff0c\u4e24\u4f1a\u59d4\u5458\u5c31\u521b\u65b0\u836f\u3001\u5fae\u751f\u7269\u3001\u8111\u79d1\u5b66\u63d0\u51fa\u76f8\u5173\u63d0\u6848\uff0c\u5305\u62ec\u63d0\u5347\u836f\u7269\u521b\u65b0\u80fd\u529b\u3001\u52a0\u5f3a\u519c\u4e1a\u5fae\u751f\u7269\u5b66\u79d1\u548c\u8111\u79d1\u5b66\u7814\u7a76\u7b49\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.gov.cn\/premier\/2022-03\/05\/content_5677248.htm<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u79d1\u6280\u90e8\u516c\u793a\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u56fd\u9645\u5408\u4f5c\u4e34\u5e8a\u8bd5\u9a8c\u5907\u6848\u60c5\u51b5<\/div>\n
\u8fd1\u65e5\uff0c\u79d1\u6280\u90e8\u516c\u793a2022\u5e742\u670811\u65e5\u81f32022\u5e742\u670817\u65e5\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u56fd\u9645\u5408\u4f5c\u4e34\u5e8a\u8bd5\u9a8c\u5907\u6848\u60c5\u51b5\uff0c\u5217\u4e3e\u4ee3\u8868\u6027\u9879\u76ee\u5982\u4e0b\uff1a<\/div>\n
\u7f3a\u5931\u578b\u03b1-\u5730\u4e2d\u6d77\u8d2b\u8840\u57fa\u56e0\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08Gap-PCR \u6cd5\uff09\u4e34\u5e8a\u8bd5\u9a8c\u2014\u2014\u4e9a\u80fd\u751f\u7269\u3001\u5e7f\u897f\u58ee\u65cf\u81ea\u6cbb\u533a\u4eba\u6c11\u533b\u9662\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/fuwu.most.gov.cn\/html\/tztg\/xzxkzx\/20220227\/123124193.html<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0FDA\u53d1\u5e033\u4efd\u764c\u75c7\u4e34\u5e8a\u8bd5\u9a8c\u6307\u5357\uff0c\u65e8\u5728\u63a8\u8fdb\u764c\u75c7\u9884\u9632\u8bca\u7597<\/div>\n
2022\u5e743\u67081\u65e5\uff0cFDA\u53d1\u5e033\u4efd\u6307\u5357\uff0c\u65e8\u5728\u63a8\u8fdb\u764c\u75c7\u9884\u9632\u8bca\u7597\uff0c\u5176\u4e2d\uff1a<\/div>\n
\u300a\u8001\u5e74\u4eba\u53c2\u4e0e\u764c\u75c7\u4e34\u5e8a\u8bd5\u9a8c\u300b\u5efa\u8bae\u5c0665\u5c81\u53ca\u4ee5\u4e0a\u7684\u8001\u5e74\u60a3\u8005\u7eb3\u5165\u764c\u75c7\u6cbb\u7597\u836f\u7269\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff1b<\/div>\n
\u300a\u6269\u5c55\u961f\u5217\uff1a\u7528\u4e8e\u9996\u6b21\u4eba\u4f53\u4e34\u5e8a\u8bd5\u9a8c\u4ee5\u52a0\u5feb\u80bf\u7624\u836f\u7269\u548c\u751f\u7269\u5236\u5242\u7684\u5f00\u53d1\u300b\u5efa\u8bae\u540c\u65f6\u5c06\u60a3\u8005\u7eb3\u5165\u4e0d\u540c\u7684\u961f\u5217\u4ee5\u8bc4\u4f30\u764c\u75c7\u836f\u7269\u7684\u5b89\u5168\u6027\u3001\u836f\u4ee3\u52a8\u529b\u5b66\u7b49\uff1b<\/div>\n
\u300a\u52a0\u5feb\u80bf\u7624\u836f\u7269\u548c\u751f\u7269\u5236\u5242\u5f00\u53d1\u7684\u6709\u6548\u4e34\u5e8a\u8bd5\u9a8c\u8bbe\u8ba1\u7b56\u7565\u300b\u6db5\u76d6\u4e34\u5e8a\u8bd5\u9a8c\u65b9\u6848\u8bbe\u8ba1\u6d41\u7a0b\u3001\u7533\u529e\u65b9\u5e94\u63d0\u4ea4\u4fe1\u606f\u7b49\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-clinical-trial-guidances-share-biden-administrations-goals-advancing-development-cancer<\/div>\n
\u00a0<\/div>\n
\u2756\u00a02022\u5e74\u201c\u5168\u7403\u5341\u5927\u7a81\u7834\u6027\u6280\u672f\u201d\u516c\u5e03\uff0c\u751f\u7269\u533b\u836f\u76f8\u5173\u6280\u672f\u5360\u56db\u5e2d<\/div>\n
\u8fd1\u65e5\uff0c\u77e5\u540d\u79d1\u6280\u5546\u4e1a\u5a92\u4f53\u300a\u9ebb\u7701\u7406\u5de5\u79d1\u6280\u8bc4\u8bba\u300b\uff08MIT Technology Review\uff09\u516c\u5e032022\u5e74\u201c\u5168\u7403\u5341\u5927\u7a81\u7834\u6027\u6280\u672f\u201d\uff0c\u5176\u4e2d\u751f\u7269\u533b\u836f\u76f8\u5173\u6280\u672f\u5360\u56db\u5e2d\uff0c\u5305\u62ec\u65b0\u51a0\u75c5\u6bd2\u53d8\u5f02\u682a\u8ffd\u8e2a\u3001AI\u9884\u6d4b\u86cb\u767d\u8d28\u7ed3\u6784\u3001\u759f\u75be\u75ab\u82d7\u4ee5\u53ca\u6cbb\u7597\u65b0\u51a0\u7684\u53e3\u670d\u836f\u7269\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.technologyreview.com\/2022\/02\/23\/1045416\/10-breakthrough-technologies-2022\/<\/div>\n
\u00a0<\/div>\n
\u9177\u5e94\u7528<\/div>\n
\u2756\u00a0\u71c3\u77f3\u533b\u5b66\u7684\u5b9e\u4f53\u7624MRD\u68c0\u6d4b\u4ea7\u54c1\u6717\u5fae\u2122\u6b63\u5f0f\u4e0a\u5e02<\/div>\n
2022\u5e743\u67081\u65e5\uff0c\u71c3\u77f3\u533b\u5b66\u81ea\u4e3b\u7814\u53d1\u7684\u5b9e\u4f53\u7624\u5fae\u5c0f\u6b8b\u7559\u75c5\u7076\uff08MRD\uff09\u68c0\u6d4b\u4ea7\u54c1\u6717\u5fae\u2122\u6b63\u5f0f\u4e0a\u5e02\u3002\u8be5\u4ea7\u54c1\u6839\u636e\u6bcf\u4e00\u4f4d\u5b9e\u4f53\u7624\u60a3\u8005\u57fa\u56e0\u53d8\u5f02\u56fe\u8c31\uff0c\u5b9a\u5236\u4e2a\u4f53\u5316MRD\u68c0\u6d4b\u65b9\u6848\uff0c\u53ef\u52a8\u6001\u8bc4\u4f30\u60a3\u8005MRD\u72b6\u6001\uff0c\u63d0\u793a\u60a3\u8005\u624b\u672f\u6216\u5176\u4ed6\u6839\u6cbb\u6027\u6cbb\u7597\u540e\u7684\u590d\u53d1\u98ce\u9669\uff0c\u540c\u65f6\u4e3a\u9884\u540e\u8bc4\u4f30\u548c\u7528\u836f\u6cbb\u7597\u63d0\u4f9b\u6307\u5bfc\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4f20\u5947\u751f\u7269\u7684CAR-T\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u83b7FDA\u6279\u51c6\u4e0a\u5e02<\/div>\n
2022\u5e742\u670828\u65e5\uff0c\u4f20\u5947\u751f\u7269\u5ba3\u5e03\uff0c\u5176\u81ea\u7814\u7684CAR-T\u7ec6\u80de\u7597\u6cd5\u4ea7\u54c1\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\uff08CARVYKTI\u00ae\uff09\u83b7\u5f97FDA\u6279\u51c6\u4e0a\u5e02\uff0c\u7528\u4e8e\u6cbb\u7597\u590d\u53d1\u6216\u96be\u6cbb\u6027\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\uff08R\/R MM\uff09\u60a3\u8005\u3002\u4f20\u5947\u751f\u7269\u4e0e\u6768\u68ee\u516c\u53f8\u4e8e2017\u5e7412\u6708\u7b7e\u8ba2\u5168\u7403\u72ec\u5bb6\u8bb8\u53ef\u548c\u5408\u4f5c\u534f\u8bae\uff0c\u4ee5\u5f00\u53d1\u548c\u5546\u4e1a\u5316\u897f\u8fbe\u57fa\u5965\u4ed1\u8d5b\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u827e\u514b\u4f26\u533b\u7597\u7684\u80ba\u764c\u8840\u6db2\u4e09\u57fa\u56e0\u7532\u57fa\u5316\u68c0\u6d4b\u8bd5\u5242\u76d2\u83b7NMPA\u6279\u51c6\u4e0a\u5e02<\/div>\n
\u8fd1\u65e5\uff0c\u827e\u514b\u4f26\u533b\u7597\u65b0\u4ea7\u54c1\u201c\u827e\u80ba\u660e\u201d\uff08SHOX2\/RASSF1A\/PTGER4\u57fa\u56e0\u7532\u57fa\u5316\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08PCR-\u8367\u5149\u63a2\u9488\u6cd5\uff09\uff09\u83b7NMPA\u6279\u51c6\u4e0a\u5e02\uff0c\u7528\u4e8e\u4f53\u5916\u68c0\u6d4b\u4eba\u5916\u5468\u8840\u8840\u6d46\u4e2dSHOX2\u3001RASSF1A\u3001PTGER4\u57fa\u56e0\u7684\u7532\u57fa\u5316\uff0c\u6709\u52a9\u4e8e\u63d0\u9ad8\u65e9\u671f\u80ba\u764c\u68c0\u51fa\u7387\uff0c\u63a8\u52a8\u6211\u56fd\u80ba\u764c\u9632\u6cbb\u5de5\u4f5c\u53d1\u5c55\u3002<\/div>\n
\u00a0<\/div>\n
\u9ed1\u79d1\u6280<\/div>\n
\u2756\u00a0\u6211\u56fd\u51a0\u5fc3\u75c5\u591a\u57fa\u56e0\u98ce\u9669\u8bc4\u5206\u6a21\u578b\u53d1\u5e03<\/div>\n
\u8fd1\u65e5\uff0c\u56fd\u5bb6\u5fc3\u8840\u7ba1\u75c5\u4e2d\u5fc3\u3001\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u961c\u5916\u533b\u9662\u987e\u4e1c\u98ce\u9662\u58eb\u548c\u9c81\u5411\u950b\u6559\u6388\u56e2\u961f\u5728European Heart Journal\u4e0a\u53d1\u5e03\u7814\u7a76\u6210\u679c\uff0c\u5efa\u7acb\u4e86\u6211\u56fd\u51a0\u5fc3\u75c5\u591a\u57fa\u56e0\u98ce\u9669\u8bc4\u5206\u6a21\u578b\uff0c\u6709\u52a9\u4e8e\u63d0\u5347\u51a0\u5fc3\u75c5\u53d1\u75c5\u98ce\u9669\u9884\u6d4b\u548c\u4e34\u5e8a\u98ce\u9669\u5206\u5c42\u80fd\u529b\uff0c\u5229\u4e8e\u51a0\u5fc3\u75c5\u7684\u65e9\u671f\u9884\u6d4b\u9884\u8b66\u548c\u7cbe\u51c6\u9632\u6cbb\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1093\/eurheartj\/ehac093<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u6e05\u534e\u5927\u5b66\u4e0e\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821\u5408\u4f5c\u5f00\u53d1\u5c0f\u578b\u3001\u9ad8\u6548CRISPR\u57fa\u56e0\u7f16\u8f91\u5de5\u5177<\/div>\n
\u8fd1\u65e5\uff0c\u6e05\u534e\u5927\u5b66\u5218\u4fca\u6770\u56e2\u961f\u4e0e\u52a0\u5dde\u5927\u5b66\u4f2f\u514b\u5229\u5206\u6821Jennifer Doudna\u56e2\u961f\u5408\u4f5c\uff0c\u5728Molecular Cell\u4e0a\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u4ed6\u4eec\u6539\u9020\u4e86CasX\u86cb\u767d\u548csgRNA\u7684\u7ed3\u6784\uff0c\u6781\u5927\u5730\u63d0\u9ad8\u4e86DpbCasX\u548cPlmCasX\u7684\u57fa\u56e0\u7f16\u8f91\u6548\u7387\uff0c\u5728GFP\u4f4d\u70b9\u4e0a\u53ef\u8fbe90%\uff0c\u5728\u5185\u6e90\u4f4d\u70b9\u4e0a\u53ef\u8fbe50%\u3002CasX\u5177\u6709\u5206\u5b50\u91cf\u5c0f\uff08\u4ec5980\u4e2a\u6c28\u57fa\u9178\uff09\u3001\u57fa\u56e0\u7f16\u8f91\u6548\u7387\u9ad8\u53ca\u975e\u7279\u5f02\u6027DNA\u5207\u5272\u6d3b\u6027\u4f4e\u7b49\u4f17\u591a\u4f18\u70b9\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/doi.org\/10.1016\/j.molcel.2022.02.002<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u7aef<\/div>\n
\u2756 \u7f8e\u56fd\u4e13\u5229\u548c\u5546\u6807\u5c40\u5224\u5b9a\u5f20\u5cf0\u56e2\u961f\u62e5\u6709\u5728\u771f\u6838\u7ec6\u80de\u4e2d\u4f7f\u7528CRISPR\u7684\u4e13\u5229<\/div>\n
2022\u5e742\u670828\u65e5\uff0c\u7f8e\u56fd\u4e13\u5229\u548c\u5546\u6807\u5c40\uff08USPTO\uff09\u5224\u5b9a\u6765\u81ea\u54c8\u4f5b\u5927\u5b66\u548c\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u535a\u5fb7\u7814\u7a76\u6240\u7684\u5f20\u950b\u56e2\u961f\u62e5\u6709\u5728\u771f\u6838\u7ec6\u80de\u4e2d\u4f7f\u7528CRISPR\u7684\u4e13\u5229\u3002\u8bfa\u5956\u5f97\u4e3bJennifer Doudna\u6307\u51fa\uff0c\u8fd9\u4e00\u5224\u5b9a\u7ed3\u679c\u4e0e\u8d85\u8fc730\u4e2a\u56fd\u5bb6\u548c\u8bfa\u8d1d\u5c14\u5956\u59d4\u5458\u4f1a\u7684\u51b3\u5b9a\u4e0d\u4e00\u81f4\uff0c\u5c06\u5230\u7f8e\u56fd\u8054\u90a6\u5de1\u56de\u4e0a\u8bc9\u6cd5\u9662\u4e0a\u8bc9\u3002\u57fa\u4e8e\u76ee\u524d\u7684\u5224\u5b9a\u7ed3\u679c\uff0cIntellia Therapeutics\u3001CRISPR Therapeutics \u7b49\u5728\u7f8e\u56fd\u8fd0\u8425\u7684CRISPR\u57fa\u56e0\u7f16\u8f91\u76f8\u5173\u516c\u53f8\uff0c\u9700\u8981\u4e0e\u5f20\u5cf0\u56e2\u961f\u8fdb\u884c\u4e13\u5229\u8c08\u5224\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u7f57\u6c0f\u79ef\u6781\u62db\u8058\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u76f8\u5173\u804c\u4f4d\uff0c\u63a8\u8fdb\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u5f00\u53d1<\/div>\n
\u8fd1\u671f\uff0c\u7f57\u6c0f\u53d1\u5e03\u4e86\u591a\u4e2a\u62db\u8058\u5c97\u4f4d\uff0c\u6db5\u76d6\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u5e73\u53f0\u6d4b\u5e8f\u6d41\u7a0b\u6240\u9700\u8bbe\u5907\u7684\u754c\u5b9a\u3001\u8bbe\u8ba1\u3001\u5f00\u53d1\u3001\u96c6\u6210\u548c\u9a8c\u8bc1\u7b49\u73af\u8282\uff0c\u610f\u5473\u7740\u7f57\u6c0f\u6b63\u79ef\u6781\u63a8\u8fdb\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u5e73\u53f0\u7814\u53d1\u8fdb\u5ea6\u30022014\u5e74\uff0c\u7f57\u6c0f\u6536\u8d2d\u4e86\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u516c\u53f8Genia Technologies\uff0c 2020\u5e74\uff0c\u7f57\u6c0f\u6536\u8d2d\u6d4b\u5e8f\u6280\u672f\u516c\u53f8Stratos Genomics\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u9a6f\u9e7f\u533b\u7597\u5357\u4eac\u751f\u4ea7\u57fa\u5730\u83b7\u5f97CAR-T\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u300a\u836f\u54c1\u751f\u4ea7\u8bb8\u53ef\u8bc1\u300b<\/div>\n
2022\u5e743\u67082\u65e5\uff0c\u9a6f\u9e7f\u533b\u7597\u5ba3\u5e03\uff0c\u516c\u53f8\u4f4d\u4e8e\u5357\u4eac\u7684\u5546\u4e1a\u5316\u751f\u4ea7\u57fa\u5730\u901a\u8fc7\u6c5f\u82cf\u7701\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08JSMPA\uff09\u7684\u5168\u9762\u5ba1\u6838\uff0c\u88ab\u6388\u4e88\u300a\u836f\u54c1\u751f\u4ea7\u8bb8\u53ef\u8bc1\u300b\u3002\u8be5\u751f\u4ea7\u57fa\u5730\u4e8e2020\u5e7411\u6708\u6295\u5165\u4f7f\u7528\uff0c\u4f5c\u4e3a\u6838\u5fc3\u8bbe\u65bd\u533a\u57df\u7684\u7ec6\u80de\u751f\u4ea7\u8f66\u95f4\u91c7\u7528\u5de5\u4f5c\u7ad9\u7684\u5f62\u5f0f\uff0c\u6309\u7167\u4e2d\u56fdGMP\u6807\u51c6\uff0c\u5e76\u53c2\u8003\u6b27\u76dfGMP\u53caFDA cGMP\u8fdb\u884c\u8bbe\u8ba1\uff0c\u8bbe\u8ba1\u4ea7\u80fd\u53ef\u5b9e\u73b0\u5e74\u751f\u4ea7CAR-T\u7ec6\u80de3000\u4eba\u4efd\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0CureVac\u6210\u7acb\u5b50\u516c\u53f8\u4ee5\u63a8\u8fdbRNA Printer\u7814\u53d1\uff0cRNA Printer\u7528\u4e8eRNA\u75ab\u82d7\u751f\u4ea7<\/div>\n
2022\u5e743\u67081\u65e5\uff0c\u5fb7\u56fd\u751f\u7269\u5236\u836f\u4f01\u4e1aCureVac\u5ba3\u5e03\u6210\u7acb\u5b50\u516c\u53f8CureVac RNA Printer GmbH\uff0c\u4ee5\u63a8\u8fdb\u5f00\u53d1CureVac\u4e0e\u7279\u65af\u62c9\u5408\u4f5c\u8bbe\u8ba1\u7684RNA Printer\uff0cRNA Printer\u7528\u4e8eGMP\u7ea7RNA\u75ab\u82d7\u548c\u6cbb\u7597\u6027\u4ea7\u54c1\u7684\u751f\u4ea7\u548c\u81ea\u52a8\u5316\u5236\u9020\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u745e\u58eb\u5236\u836f\u516c\u53f8Santhera\u4e0eSEAL Therapeutics\u7b7e\u7f72\u57fa\u56e0\u6cbb\u7597\u534f\u8bae<\/div>\n
2022\u5e742\u670828\u65e5\uff0cSanthera\u5ba3\u5e03\u4e0e\u745e\u58eb\u5df4\u585e\u5c14\u5927\u5b66\u5b50\u516c\u53f8SEAL Therapeutics\u7b7e\u7f72\u534f\u8bae\uff0c\u5f00\u53d1\u4e00\u79cd\u9488\u5bf9LAMA2\u7f3a\u9677\u578b\u5148\u5929\u6027\u808c\u8425\u517b\u4e0d\u826f\u75c7(LAMA2 MD)\u7684\u57fa\u56e0\u7597\u6cd5\u3002Santhera\u5c06\u6709\u8d44\u683c\u83b7\u5f97\u57fa\u4e8eSEAL Therapeutics\u672a\u6765\u6536\u76ca\u7684\u4ed8\u6b3e\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u6d4b\u5e8f\u8bbe\u5907\u7814\u53d1\u5546Singular\u4e0e\u7f57\u6c0f\u3001\u5b89\u6377\u4f26\u3001Qiagen\u8fbe\u6210\u5408\u4f5c\uff0c1\u6708\u5df2\u4e0e6\u5bb6\u516c\u53f8\u8fbe\u6210\u5408\u4f5c<\/div>\n
2022\u5e742\u670828\u65e5\uff0cSingular Genomics Systems\u5ba3\u5e03\uff0c\u5df2\u4e0e\u7f57\u6c0f\u3001\u5b89\u6377\u4f26\u548cQiagen\u8fbe\u6210\u5408\u4f5c\uff0c\u786e\u4fddSingular\u7684G4\u6d4b\u5e8f\u7cfb\u7edf\u80fd\u4e0e\u4e0a\u8ff0\u516c\u53f8\u7684\u6837\u54c1\u548c\u6587\u5e93\u5236\u5907\u8bd5\u5242\u76d2\u517c\u5bb9\u30022022\u5e741\u6708\uff0cSingular\u5df2\u4e0eTwist Bioscience\u3001Lexogen\u7b496\u4e2a\u516c\u53f8\u8fbe\u6210\u5408\u4f5c\u3002G4\u6d4b\u5e8f\u5e73\u53f0\u53ef\u72ec\u7acb\u8fd0\u884c16\u4e2a\u6837\u672c\uff0c\u5e76\u5c06\u6d4b\u5e8f\u65f6\u95f4\u7f29\u77ed\u81f3\u51e0\u5c0f\u65f6\uff0cG4\u5e73\u53f0\u53ca\u5176\u8017\u6750\u8bd5\u5242\u76d2\u9884\u8ba1\u5c06\u4e8e2022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u5f00\u59cb\u53d1\u8d27\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u201c\u6d59\u6c5f\u745e\u9e25\u516c\u76ca\u57fa\u91d1\u4f1a\u201d\u6b63\u5f0f\u6210\u7acb\uff0c\u4e13\u6ce8\u4e8e\u7f55\u89c1\u75c5\u79d1\u5b66\u7814\u7a76\u4e0e\u8f6c\u5316\u533b\u5b66<\/div>\n
2022\u5e742\u670828\u65e5\uff0c\u6d59\u6c5f\u745e\u9e25\u516c\u76ca\u57fa\u91d1\u4f1a\u5728\u676d\u5dde\u672a\u6765\u79d1\u6280\u57ce\u6b63\u5f0f\u6210\u7acb\u3002\u8be5\u57fa\u91d1\u4f1a\u7531\u853b\u5fb7\u7f55\u89c1\u75c5\u4e2d\u5fc3\u521b\u59cb\u4eba\u9ec4\u5982\u65b9\u5148\u751f\u5021\u8bae\u53d1\u8d77\uff0c\u7531\u4e2d\u5357\u5927\u5b66\u5468\u5b8f\u704f\u9662\u58eb\u7b4912\u4f4d\u77e5\u540d\u79d1\u5b66\u5bb6\u548c\u4f01\u4e1a\u5bb6\u5171\u540c\u53d1\u8d77\u521b\u7acb\u3002\u8be5\u57fa\u91d1\u4f1a\u662f\u4e00\u4e2a\u521b\u65b0\u578b\u516c\u76ca\u57fa\u91d1\u4f1a\uff0c\u65e8\u5728\u6210\u4e3a\u7f55\u89c1\u75c5\u79d1\u5b66\u7814\u7a76\u548c\u8f6c\u5316\u533b\u5b66\u7684\u521b\u65b0\u5f15\u64ce\u3002<\/div>\n
\u00a0<\/div>\n
\u6295\u878d\u8d44<\/div>\n
\u2756\u00a0\u4f53\u5916\u8bca\u65ad\u4f01\u4e1a\u83f2\u9e4f\u751f\u72693\u67083\u65e5\u521b\u4e1a\u677f\u9996\u53d1\u4e0a\u4f1a\u901a\u8fc7<\/div>\n
2022\u5e743\u67083\u65e5\uff0c\u83f2\u9e4f\u751f\u7269\u521b\u4e1a\u677f\u9996\u53d1\u4e0a\u4f1a\u901a\u8fc7\u3002\u83f2\u9e4f\u751f\u7269\u81f4\u529b\u4e8e\u4f53\u5916\u8bca\u65ad\u8bd5\u5242\u6838\u5fc3\u539f\u6599\u7684\u7814\u53d1\u3001\u751f\u4ea7\u548c\u9500\u552e\uff0c\u5e76\u4e3a\u5ba2\u6237\u63d0\u4f9b\u4f53\u5916\u8bca\u65ad\u4eea\u5668\u4e0e\u8bd5\u5242\u6574\u4f53\u89e3\u51b3\u65b9\u6848\u3002\u83f2\u9e4f\u751f\u7269IPO\u4e0a\u5e02\u62db\u80a1\u4e66\u663e\u793a\uff0c\u516c\u53f8\u62df\u52df\u96c6\u8d44\u91d125.06\u4ebf\u5143\uff0c\u4e3b\u8981\u7528\u4e8e\u4f53\u5916\u8bca\u65ad\u8bd5\u5242\u6838\u5fc3\u539f\u6599\u5efa\u8bbe\uff0c\u4f53\u5916\u8bca\u65ad\u4eea\u5668\u53ca\u914d\u5957\u8bd5\u5242\u89e3\u51b3\u65b9\u6848\u7814\u53d1\u3001\u751f\u4ea7\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u57fa\u56e0\u6cbb\u7597\u836f\u7269\u7814\u53d1\u5546\u534e\u6bc5\u4e50\u5065\u5b8c\u6210\u6570\u4ebf\u5143\u4eba\u6c11\u5e01A\u8f6e\u878d\u8d44<\/div>\n
2022\u5e743\u67082\u65e5\uff0c\u57fa\u56e0\u6cbb\u7597\u836f\u7269\u7814\u53d1\u5546\u534e\u6bc5\u4e50\u5065\u5b8c\u6210\u6570\u4ebf\u5143\u4eba\u6c11\u5e01A\u8f6e\u878d\u8d44\uff0c\u7531\u7ea2\u6749\u4e2d\u56fd\u9886\u6295\uff0c\u9633\u5149\u4fdd\u9669\u3001\u5317\u4eac\u751f\u547d\u56ed\u521b\u6295\u57fa\u91d1\u3001\u6e05\u677e\u8d44\u672c\u8ddf\u6295\uff0c\u8001\u80a1\u4e1c\u5149\u5927\u63a7\u80a1\u3001\u679c\u5b9e\u76c8\u5bcc\u3001\u534e\u5174\u8d44\u672c\u7ee7\u7eed\u52a0\u6301\u3002\u672c\u8f6e\u878d\u8d44\u5c06\u4e3b\u8981\u7528\u4e8e\u63a8\u8fdb\u5148\u5bfc\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u7684\u751f\u4ea7\u3001\u6ce8\u518c\u3001\u4e34\u5e8a\u548c\u7814\u7a76\uff0c\u4ee5\u53ca\u52a0\u901f\u5728\u5176\u4ed6\u9776\u5411\u809d\u810f\u548c\u9776\u5411\u795e\u7ecf\u9886\u57df\u4ea7\u54c1\u7684\u5f00\u53d1\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u764c\u75c7\u8bc4\u4f30\u8f6f\u4ef6\u7814\u53d1\u5546CancerIQ\u5b8c\u62101400\u4e07\u7f8e\u5143B\u8f6e\u878d\u8d44<\/div>\n
2022\u5e743\u67083\u65e5\uff0c\u764c\u75c7\u8bc4\u4f30\u8f6f\u4ef6\u7814\u53d1\u5546CancerIQ\u5b8c\u62101400\u4e07\u7f8e\u5143B\u8f6e\u878d\u8d44\uff0cMerck Global Health Innovation Fund\u548cAmgen Ventures\u9886\u6295\uff0cMcKesson Ventures\u7b49\u53c2\u6295\u3002\u672c\u8f6e\u8d44\u91d1\u5c06\u7528\u4e8e\u4f18\u5316\u5176\u764c\u75c7\u8bc4\u4f30\u8f6f\u4ef6CancerIQ\u5e73\u53f0\uff0c\u5e76\u6269\u5927\u5ba2\u6237\u7fa4\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u5373\u65f6\u8bca\u65ad\u8bbe\u5907\u7814\u53d1\u5546\u5965\u7136\u751f\u7269\u5b8c\u6210\u6570\u4ebf\u5143\u4eba\u6c11\u5e01C\u8f6e\u878d\u8d44<\/div>\n
\u8fd1\u65e5\uff0c\u5965\u7136\u751f\u7269\u5b8c\u6210\u6570\u4ebf\u5143\u4eba\u6c11\u5e01C\u8f6e\u878d\u8d44\uff0c\u7531\u6668\u5174\u521b\u6295\u9886\u6295\uff0c\u5c71\u84dd\u8d44\u672c\u3001\u7845\u6e2f\u8d44\u672c\u3001\u5eb7\u534e\u751f\u7269\u8ddf\u6295\uff0c\u539f\u80a1\u4e1c\u90a6\u52e4\u8d44\u672c\u4ee5\u53ca\u5929\u4f7f\u6295\u80a1\u4e1c\u8ffd\u52a0\u6295\u8d44\u3002\u5965\u7136\u751f\u7269\u4e13\u6ce8\u4e8e\u5373\u65f6\u5206\u5b50\u8bca\u65ad\u8bbe\u5907\u7684\u7814\u53d1\u751f\u4ea7\uff0c\u672c\u8f6e\u8d44\u91d1\u5c06\u4e3b\u8981\u7528\u4e8e\u4e34\u5e8a\u4ea7\u54c1\u6ce8\u518c\u3001\u4ea7\u54c1\u5546\u4e1a\u5316\u63a8\u8fdb\u3001\u5168\u81ea\u52a8\u751f\u4ea7\u7ebf\u6269\u5efa\u548c\u65b0\u4ea7\u54c1\u7814\u53d1\u7b49\u65b9\u9762\u3002<\/div>\n
\u00a0<\/div>\n
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\u8fd1\u65e5\uff0c\u79d1\u91d1\u751f\u7269\u5b8c\u6210\u8fd1\u4ebf\u5143\u4eba\u6c11\u5e01\u5929\u4f7f\u8f6e\u878d\u8d44\uff0c\u7531\u5e42\u65b9\u8d44\u672c\u9886\u6295\uff0c\u91d1\u6d66\u5065\u5eb7\u57fa\u91d1\u4ee5\u53ca\u65e0\u9521\u91d1\u7a0b\u6620\u6708\u5929\u4f7f\u57fa\u91d1\u8ddf\u6295\u3002\u79d1\u91d1\u751f\u7269\u4e13\u6ce8\u4e8e\u7528\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u4e0e\u7ec6\u80de\u7597\u6cd5\u6cbb\u7597\u7f55\u89c1\u75c5\u4ee5\u53ca\u6297\u764c\u65b0\u836f\u7814\u53d1\u53ca\u751f\u4ea7\uff0c\u672c\u8f6e\u878d\u8d44\u4e3b\u8981\u7528\u4e8e\u63a8\u8fdb\u516c\u53f8\u7b2c\u4e00\u4e2a\u7f55\u89c1\u75c5\u4ea7\u54c1\u7ba1\u7ebf\u2014\u2014\u4e19\u916e\u9178\u6fc0\u9176\u7f3a\u4e4f\u75c7\u5728\u4e2d\u56fd\u4ee5\u53ca\u6b27\u6d32\u7684\u4e24\u4e2aIND\u7533\u62a5\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u7f55\u89c1\u75c5\u57fa\u56e0\u7597\u6cd5\u7814\u53d1\u5546\u51cc\u610f\u751f\u7269\u5b8c\u6210\u8fd1\u4ebf\u5143Pre-A\u53caPre-A+\u8f6e\u878d\u8d44<\/div>\n
2022\u5e742\u670828\u65e5\uff0c\u51cc\u610f\u751f\u7269\u5ba3\u5e03\u5b8c\u6210\u8fd1\u4ebf\u5143Pre-A\u53caPre-A+\u8f6e\u878d\u8d44\uff0c\u5176\u4e2dPre-A\u8f6e\u7531\u7ecf\u7eac\u521b\u6295\u72ec\u5bb6\u6295\u8d44\uff0cPre-A+\u8f6e\u7531\u7ea2\u6749\u4e2d\u56fd\u72ec\u5bb6\u6295\u8d44\uff0c\u6d69\u60a6\u8d44\u672c\u62c5\u4efb\u72ec\u5bb6\u8d22\u52a1\u987e\u95ee\u3002\u51cc\u610f\u751f\u7269\u62e5\u6709\u7f55\u89c1\u75c5\u52a8\u7269\u6a21\u578b\u529f\u80fd\u9a8c\u8bc1\u5e73\u53f0\uff0c\u81f4\u529b\u4e8e\u9057\u4f20\u6027\u7f55\u89c1\u75c5\u57fa\u56e0\u7597\u6cd5\u7814\u53d1\uff0c\u672c\u8f6e\u8d44\u91d1\u5c06\u7528\u4e8e\u63a8\u52a8\u516c\u53f8\u7f55\u89c1\u75c5\u52a8\u7269\u6a21\u578b\u5e73\u53f0\u5b8c\u5584\u53ca\u591a\u6b3e\u9886\u5148\u7684\u57fa\u56e0\u7597\u6cd5\u7ba1\u7ebf\u7684\u4e34\u5e8a\u524d\u7814\u53d1\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u5206\u5b50\u8bca\u65ad\u65b0\u9510\u4f01\u4e1a\u95ea\u91cf\u79d1\u6280\u5b8c\u6210\u8fd1\u4ebf\u5143A\u8f6e\u878d\u8d44<\/div>\n
\u8fd1\u65e5\uff0c\u95ea\u91cf\u79d1\u6280\u5b8c\u6210\u8fd1\u4ebf\u5143A\u8f6e\u878d\u8d44\uff0c\u7531\u590d\u661f\u521b\u5bcc\uff08\u6df1\u5733\uff09\u52a8\u529b\u79d1\u6280\u5929\u4f7f\u57fa\u91d1\u9886\u6295\uff0c\u5143\u751f\u521b\u6295\u8ddf\u6295\uff0c\u539f\u80a1\u4e1c\u6d59\u6c11\u6295\u52a0\u6301\u3002\u95ea\u91cf\u79d1\u6280\u57fa\u4e8e\u5fae\u9635\u5217-\u5b9a\u91cf\u8367\u5149\u6838\u9178\u6269\u589e(microarray-qPCR)\u4e13\u5229\u6280\u672f\uff0c\u63a8\u51fa\u8d85\u591a\u91cd\u8367\u5149\u5b9a\u91cfPCR\u5e73\u53f0\u3002\u672c\u8f6e\u878d\u8d44\u5c06\u52a0\u5feb\u5168\u81ea\u52a8\u5206\u5b50\u8bca\u65ad\u7cfb\u5217\u4ea7\u54c1\u7684\u7814\u53d1\u3001\u4ea7\u54c1\u6ce8\u518c\u3001\u8f6c\u4ea7\u5e76\u63a8\u8fdb\u5546\u4e1a\u5316\u8fdb\u7a0b\u3002<\/div>\n
\u00a0<\/div>\n
\u4f1a\u8bae\u63a8\u8350<\/div>\n
\u2756\u00a0\u7b2c\u4e09\u5c4a\u56fd\u9645\u4eba\u7c7b\u57fa\u56e0\u7f16\u8f91\u5cf0\u4f1a\u524d\u77bb\u6f14\u8bb2\uff0c2022\u5e743\u67087~9\u65e5\uff0c\u7ebf\u4e0a\u516c\u5f00\u6f14\u8bb2<\/div>\n
\u672c\u6b21\u6d3b\u52a8\u7531\u82f1\u56fd\u7687\u5bb6\u5b66\u4f1a\u4e0e\u82f1\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u3001\u7f8e\u56fd\u56fd\u5bb6\u79d1\u5b66\u9662\u548c\u533b\u5b66\u9662\u4ee5\u53ca\u4e16\u754c\u79d1\u5b66\u9662\u8054\u5408\u7ec4\u7ec7\uff0c\u662f2023\u5e743\u67086\u65e5\u81f38\u65e5\u4e3e\u529e\u76842023\u5e74\u7b2c\u4e09\u5c4a\u4eba\u7c7b\u57fa\u56e0\u7ec4\u7f16\u8f91\u56fd\u9645\u5cf0\u4f1a\u524d\u77bb\u6f14\u8bb2\uff0c\u53ef\u5728\u7ebf\u89c2\u770b\u3002\u6f14\u8bb2\u5185\u5bb9\u5305\u62ec\uff1a<\/div>\n
\u79d1\u5b66\u73b0\u72b6\u548c\u4f53\u7ec6\u80de\u7f16\u8f91\u7684\u6700\u65b0\u53d1\u5c55\uff1b<\/div>\n
\u533b\u7597\u536b\u751f\u7cfb\u7edf\u5728\u83b7\u53d6\u65b0\u7684\u4f53\u7ec6\u80de\u57fa\u56e0\u7ec4\u7f16\u8f91\u6280\u672f\u65b9\u9762\u7684\u969c\u788d\uff0c\u4ee5\u53ca\u5bf9\u5f53\u524d\u76d1\u7ba1\u6846\u67b6\u7684\u7814\u7a76\uff1b<\/div>\n
\u4f53\u7ec6\u80de\u548c\u53ef\u9057\u4f20\u7f16\u8f91\u6cbb\u7406\u9762\u4e34\u7684\u6311\u6218\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/royalsociety.org\/science-events-and-lectures\/2022\/03\/looking-ahead-to-the-third-human-genome-editing-summit\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u7b2c\u4e00\u5c4a\u4e2d\u56fd\u667a\u80fd\u5065\u5eb7\u4e0e\u751f\u7269\u4fe1\u606f\u5927\u4f1a\uff0c2022\u5e743\u670825~27\u65e5\uff0c\u798f\u5efa\u798f\u5dde<\/div>\n
\u8be5\u4f1a\u8bae\u7531\u4e2d\u56fd\u81ea\u52a8\u5316\u5b66\u4f1a\u4e3b\u529e\uff0c\u65e8\u5728\u5f00\u5c55\u667a\u80fd\u5065\u5eb7\u4e0e\u751f\u7269\u4fe1\u606f\u79d1\u5b66\u6280\u672f\u548c\u4ea7\u4e1a\u53d1\u5c55\u6218\u7565\u7684\u7814\u7a76\u63a2\u8ba8\u3001\u4fc3\u8fdb\u667a\u80fd\u5065\u5eb7\u4e0e\u751f\u7269\u4fe1\u606f\u53ca\u76f8\u5173\u9886\u57df\u79d1\u5b66\u6280\u672f\u7684\u521b\u65b0\u5f00\u53d1\u548c\u5e94\u7528\uff0c\u5c06\u9080\u8bf7\u667a\u80fd\u5065\u5eb7\u4e0e\u751f\u7269\u4fe1\u606f\u9886\u57df\u8457\u540d\u7684\u56fd\u5185\u5916\u4e13\u5bb6\u505a\u7279\u9080\u62a5\u544a\uff0c\u5e76\u5206\u591a\u4e2a\u4e3b\u9898\u5bf9\u76f8\u5173\u9886\u57df\u7684\u6700\u65b0\u7814\u7a76\u8fdb\u5c55\u548c\u52a8\u5411\u8fdb\u884c\u62a5\u544a\u4ea4\u6d41\u3002\uff08\u70b9\u51fb\u67e5\u770b\u8be6\u60c5<\/a>\uff09<\/div>\n
\u00a0<\/div>\n
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\u6587\u7ae0 | \u57fa\u56e0\u6167\u00a0\u00a0<\/div>\n
\u7f16\u8f91 | Kathy\u00a0<\/div>\n\n
\n
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\u00a0<\/div>\n
\u00a0\u5173\u4e8e\u6211\u4eec\u00a0<\/div>\n
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