{"id":8748,"date":"2022-03-28T08:00:00","date_gmt":"2022-03-28T00:00:00","guid":{"rendered":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/03\/28\/984897-2\/"},"modified":"2026-04-01T12:31:15","modified_gmt":"2026-04-01T04:31:15","slug":"984897-2","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/03\/28\/984897-2\/","title":{"rendered":"\u57fa\u56e0\u7b80\u62a5\uff08182\u671f\uff09"},"content":{"rendered":"
\n
\"RmFicvQBAkgArd371ayccZ0h7b1kYMcLjfOJjqyYaicggtUOt4GZejHKvHdYRhPW7uQicuY0VUdyFt2hQoYekWYjA\"\/<\/figure><\/div>\n\n
\u4fe1\u606f\u901f\u89c8<\/div>\n
\u2776\u56fd\u5bb6\u533b\u4fdd\u5c40\u53d1\u5e03\u52a0\u5f3a\u65b0\u51a0\u6297\u539f\u68c0\u6d4b\u4ef7\u683c\u7ba1\u7406\u7684\u901a\u77e5<\/div>\n
\u2777\u56fd\u5bb6\u533b\u4fdd\u5c40\u5c06\u65b0\u51a0\u6297\u539f\u68c0\u6d4b\u4e34\u65f6\u6027\u7eb3\u5165\u533b\u4fdd<\/div>\n
\u2778\u00a0\u56fd\u5bb6\u536b\u5065\u59d4\u5370\u53d1\u300a\u533a\u57df\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u6838\u9178\u68c0\u6d4b\u7ec4\u7ec7\u5b9e\u65bd\u6307\u5357\uff08\u7b2c\u4e09\u7248\uff09\u300b<\/div>\n
\u2779\u00a0\u56fd\u5bb6\u764c\u75c7\u4e2d\u5fc3\u53d1\u5e03\u6700\u65b0\u5168\u56fd\u764c\u75c7\u7edf\u8ba1\u6570\u636e<\/div>\n
\u277a\u00a0\u7528\u4e8e\u6cbb\u7597\u795e\u7ecf\u6bcd\u7ec6\u80de\u7624\u7684MDM2-p53\u6291\u5236\u5242\u83b7FDA\u513f\u7ae5\u7f55\u89c1\u75c5\u8d44\u683c\u8ba4\u8bc1<\/div>\n
\u277b\u00a0\u4f53\u7ec6\u80de\u8bf1\u5bfc\u51fa\u5168\u80fd\u5e72\u7ec6\u80de\uff0c\u6bd4\u8bfa\u5956\u8bf1\u5bfc\u7684\u5e72\u7ec6\u80de\u63d0\u524d3\u5929<\/div>\n
\u277c\u00a0\u4e2d\u56fd\u79d1\u7814\u56e2\u961f\u53d1\u73b0\u7389\u7c73\u3001\u6c34\u7a3b\u201c\u9ad8\u4ea7\u57fa\u56e0\u201d<\/div>\n
\u277d\u00a0\u8bca\u65ad\u68c0\u6d4b\u670d\u52a1\u5546\u4e91\u5eb7\u96c6\u56e2\u5411\u6e2f\u4ea4\u6240\u4e3b\u677f\u63d0\u4ea4\u4e0a\u5e02\u7533\u8bf7<\/div>\n
\u277e\u00a0\u57fa\u56e0\u6cbb\u7597CDMO\u516c\u53f8\u548c\u5143\u751f\u7269\u79d1\u521b\u677f\u4e0a\u5e02<\/div>\n
\u277f\u00a0\u4f55\u6c0f\u773c\u79d1\u6b63\u5f0f\u767b\u9646\u521b\u4e1a\u677f\uff0c\u672a\u6765\u5c06\u5e03\u5c40\u57fa\u56e0\u68c0\u6d4b<\/div>\n
\u00a0<\/div>\n
\u5b8f\u89c2\u9762<\/div>\n
\u2756\u00a0\u56fd\u5bb6\u533b\u4fdd\u5c40\u53d1\u5e03\u52a0\u5f3a\u65b0\u51a0\u6297\u539f\u68c0\u6d4b\u4ef7\u683c\u7ba1\u7406\u7684\u901a\u77e5<\/div>\n
2022\u5e743\u670825\u65e5\uff0c\u56fd\u5bb6\u533b\u4fdd\u5c40\u53d1\u5e03\u52a0\u5f3a\u65b0\u51a0\u6297\u539f\u68c0\u6d4b\u4ef7\u683c\u7ba1\u7406\u7684\u901a\u77e5\uff0c\u5176\u4e2d\u63d0\u5230\uff0c\u516c\u7acb\u533b\u7597\u673a\u6784\u5f00\u5c55\u7684\u65b0\u51a0\u6297\u539f\u68c0\u6d4b\u670d\u52a1\uff0c\u5141\u8bb8\u6309\u7167\u201c\u4ef7\u683c\u9879\u76ee+\u68c0\u6d4b\u8bd5\u5242\u201d\u7684\u65b9\u5f0f\u6536\u8d39\uff0c\u201c\u65b0\u51a0\u6297\u539f\u68c0\u6d4b\u201d\u4ef7\u683c\u9879\u76ee\u6700\u9ad8\u9650\u4ef7\u4e3a\u6bcf\u4eba\u6b215\u5143\uff0c\u201c\u4ef7\u683c\u9879\u76ee+\u68c0\u6d4b\u8bd5\u5242\u201d\u7684\u6536\u8d39\u603b\u989d\u73b0\u9636\u6bb5\u5c01\u9876\u6807\u51c6\u4e0d\u5f97\u9ad8\u4e8e\u6bcf\u4eba\u6b2115\u5143\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.nhsa.gov.cn\/art\/2022\/3\/25\/art_37_8017.html<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u56fd\u5bb6\u533b\u4fdd\u5c40\u5c06\u65b0\u51a0\u6297\u539f\u68c0\u6d4b\u4e34\u65f6\u6027\u7eb3\u5165\u533b\u4fdd<\/div>\n
2022\u5e743\u670821\u65e5\uff0c\u56fd\u5bb6\u533b\u4fdd\u5c40\u53d1\u5e03\u5173\u4e8e\u5207\u5b9e\u505a\u597d\u5f53\u524d\u75ab\u60c5\u9632\u63a7\u533b\u7597\u4fdd\u969c\u5de5\u4f5c\u7684\u901a\u77e5\u3002\u5176\u4e2d\u63d0\u5230\uff0c\u5404\u7701\u4efd\u53ef\u5c06\u65b0\u51a0\u6297\u539f\u68c0\u6d4b\u8bd5\u5242\u53ca\u76f8\u5e94\u68c0\u6d4b\u9879\u76ee\u4e34\u65f6\u6027\u7eb3\u5165\u57fa\u672c\u533b\u4fdd\u533b\u7597\u670d\u52a1\u9879\u76ee\u76ee\u5f55\u3002\u6b64\u5916\uff0c\u8fd8\u5c06\u53ca\u65f6\u8c03\u6574\u7eb3\u5165\u533b\u4fdd\u652f\u4ed8\u8303\u56f4\u7684\u65b0\u51a0\u6cbb\u7597\u7528\u836f\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.nhsa.gov.cn\/art\/2022\/3\/21\/art_37_7962.html<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u56fd\u5bb6\u536b\u5065\u59d4\u5370\u53d1\u300a\u533a\u57df\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u6838\u9178\u68c0\u6d4b\u7ec4\u7ec7\u5b9e\u65bd\u6307\u5357\uff08\u7b2c\u4e09\u7248\uff09\u300b<\/div>\n
\u8fd1\u671f\uff0c\u56fd\u5bb6\u536b\u5065\u59d4\u5370\u53d1\u300a\u533a\u57df\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\u6838\u9178\u68c0\u6d4b\u7ec4\u7ec7\u5b9e\u65bd\u6307\u5357\uff08\u7b2c\u4e09\u7248\uff09\u300b\uff0c\u6587\u4ef6\u7684\u91cd\u70b9\u4fee\u8ba2\u5185\u5bb9\u5982\u4e0b\uff1a<\/div>\n
\u7cbe\u51c6\u5212\u5b9a\u68c0\u6d4b\u8303\u56f4\uff0c\u5c06\u7b2c\u4e8c\u7248\u4e2d\u201c\u5168\u5458\u201d\u4fee\u6539\u4e3a\u201c\u533a\u57df\u201d\uff0c\u533a\u57df\u5927\u5c0f\u7531\u75ab\u60c5\u9632\u63a7\u9700\u8981\u51b3\u5b9a\uff0c\u6307\u5bfc\u5404\u5730\u5bf9\u5212\u5b9a\u7684\u533a\u57df\u5b8c\u6210\u6838\u9178\u68c0\u6d4b\u3002<\/div>\n
\u8fdb\u4e00\u6b65\u660e\u786e\u5b8c\u6210\u65f6\u9650\u8981\u6c42\uff0c\u89c4\u5b9a\u4e86\u5212\u5b9a\u8303\u56f4\u7684\u6838\u9178\u68c0\u6d4b\u5e94\u5f53\u572824\u5c0f\u65f6\u5185\u5b8c\u6210\u3002<\/div>\n
\u5404\u5730\u53ef\u6309\u7167\u5b9e\u9645\u60c5\u51b5\u7075\u6d3b\u589e\u8bbe\u6570\u636e\u7edf\u8ba1\u4e13\u73ed\u3001\u91c7\u68c0\u5339\u914d\u4e13\u73ed\u7b49\u5de5\u4f5c\u4e13\u73ed\uff0c\u89c4\u5b9a\u4e86\u4e13\u73ed\u804c\u8d23\u3002<\/div>\n
\u63d0\u4f9b\u68c0\u6d4b\u529b\u91cf\u6d4b\u7b97\u4f9d\u636e\uff0c\u5305\u62ec24\u5c0f\u65f6\u5185\u5b8c\u6210\u6838\u9178\u68c0\u6d4b\u6240\u9700\u7684\u91c7\u6837\u4eba\u5458\u6570\u3001\u6838\u9178\u68c0\u6d4b\u80fd\u529b\u7b49\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.nhc.gov.cn\/xcs\/zhengcwj\/202203\/b5aaa96dfe1b4f14b19bf2f888a10673.shtml?R0NMKk6uozOC=1648197092736<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u90d1\u5dde\u5f00\u5c55\u4e5d\u79cd\u65e0\u521b\u5355\u57fa\u56e0\u75c5\u4ea7\u524d\u8bca\u65ad\uff0c\u652f\u6301\u90ae\u5bc4\u8840\u6837\u65e0\u9700\u5230\u573a<\/div>\n
2022\u5e743\u670825\u65e5\uff0c\u90d1\u5dde\u5927\u5b66\u7b2c\u4e00\u9644\u5c5e\u533b\u9662\u9057\u4f20\u4e0e\u4ea7\u524d\u8bca\u65ad\u4e2d\u5fc3\u5f00\u5c55\u4e5d\u79cd\u5e38\u89c1\u5355\u57fa\u56e0\u75c5\u7684\u65e0\u521b\u6027\u4ea7\u524d\u8bca\u65ad\u670d\u52a1\uff0c\u5305\u62ec\u9057\u4f20\u6027\u8033\u804b\u3001\u8840\u53cb\u75c5\u7b49\u3002\u7531\u4e8e\u75ab\u60c5\u5f71\u54cd\uff0c\u5b55\u5987\u53ea\u9700\u5728\u5c45\u4f4f\u5730\u62bd\u8840\u90ae\u5bc4\u5230\u90d1\u5927\u4e00\u9644\u9662\u5373\u53ef\uff0c\u65e0\u9700\u5230\u573a\u3002\uff08\u70b9\u51fb\u67e5\u770b\u8be6\u60c5<\/a>\uff09<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u56fd\u5bb6\u764c\u75c7\u4e2d\u5fc3\u53d1\u5e03\u6700\u65b0\u5168\u56fd\u764c\u75c7\u7edf\u8ba1\u6570\u636e<\/div>\n
\u8fd1\u65e5\uff0c\u56fd\u5bb6\u764c\u75c7\u4e2d\u5fc3\u53d1\u5e03\u4e86\u6700\u65b0\u4e00\u671f\u7684\u5168\u56fd\u764c\u75c7\u7edf\u8ba1\u6570\u636e\u3002\u76ee\u524d\u6211\u56fd\u6076\u6027\u80bf\u7624\u76845\u5e74\u751f\u5b58\u7387\u4e3a40.5%\uff0c\u4e0e10\u5e74\u524d\u76f8\u6bd4\uff0c\u6211\u56fd\u6076\u6027\u80bf\u7624\u7684\u6574\u4f53\u751f\u5b58\u7387\u63d0\u9ad8\u4e8610\u4e2a\u767e\u5206\u70b9\uff0c\u53cd\u6620\u4e86\u6211\u56fd\u764c\u75c7\u6cbb\u7597\u6c34\u5e73\u7684\u4e0a\u5347\u3002\u4f46\u4e0e\u53d1\u8fbe\u56fd\u5bb6\u76f8\u6bd4\u8fd8\u6709\u660e\u663e\u5dee\u8ddd\uff0c\u6709\u8f83\u5927\u7684\u63d0\u5347\u7a7a\u95f4\u3002\u5982\u9884\u540e\u8f83\u597d\u7684\u51e0\u79cd\u764c\u75c7\uff0c\u5728\u6211\u56fd\u76845\u5e74\u751f\u5b58\u7387\u4e3a\uff0c\u4e73\u817a\u764c82\uff05\u3001\u7532\u72b6\u817a\u764c84\uff05\u3001\u524d\u5217\u817a\u764c66\uff05\uff0c\u800c\u53d1\u8fbe\u56fd\u5bb6\u76845\u5e74\u751f\u5b58\u7387\u4e3a\u4e73\u817a\u764c91\uff05\u3001\u7532\u72b6\u817a\u764c98\uff05\u3001\u524d\u5217\u817a\u764c99%\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.sciencedirect.com\/science\/article\/pii\/S2667005422000047<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u300a2021\u65b0\u751f\u513f\u57fa\u56e0\u7b5b\u67e5\u4e13\u5bb6\u5171\u8bc6\u300b\u53d1\u5e03<\/div>\n
\u8fd1\u671f\uff0c\u6211\u56fd\u4e2d\u534e\u533b\u5b66\u4f1a\u7b49\u673a\u6784\u5236\u5b9a\u7684\u300a2021\u65b0\u751f\u513f\u57fa\u56e0\u7b5b\u67e5\u4e13\u5bb6\u5171\u8bc6\u300b\u5728World Journal of Pediatrics\u4e0a\u53d1\u5e03\uff0c\u5171\u8bc6\u4e2d\u89c4\u5b9a\u4e86\u65b0\u751f\u513f\u57fa\u56e0\u7b5b\u67e5\u7684\u57fa\u672c\u539f\u5219\u3001\u8981\u6c42\u3001\u5de5\u4f5c\u6d41\u7a0b\u4ee5\u53ca\u7b5b\u67e5\u7ed3\u679c\u7684\u89e3\u8bfb\u539f\u5219\uff0c\u4ee5\u8fdb\u4e00\u6b65\u89c4\u8303\u5316\u65b0\u751f\u513f\u57fa\u56e0\u7b5b\u67e5\u6d41\u7a0b\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/link.springer.com\/article\/10.1007\/s12519-022-00522-8<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u79d1\u6280\u90e8\u53d1\u5e03\u300a\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u7ba1\u7406\u6761\u4f8b\u5b9e\u65bd\u7ec6\u5219\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b<\/div>\n
2022\u5e743\u670822\u65e5\uff0c\u79d1\u6280\u90e8\u53d1\u5e03\u300a\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u7ba1\u7406\u6761\u4f8b\u5b9e\u65bd\u7ec6\u5219\uff08\u5f81\u6c42\u610f\u89c1\u7a3f\uff09\u300b\u3002\u8be5\u5b9e\u65bd\u7ec6\u5219\u57fa\u4e8e2019\u5e746\u6708\u53d1\u5e03\u7684\u300a\u4e2d\u56fd\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u7ba1\u7406\u6761\u4f8b\u300b\u57fa\u7840\u4e0a\u7ec6\u5316\uff0c\u660e\u786e\u4e86\u201c\u5916\u65b9\u5355\u4f4d\u201d\u7684\u5177\u4f53\u6807\u51c6\u3001\u4f18\u5316\u5ba1\u6279\/\u5907\u6848\u5236\u5ea6\u548c\u6d41\u7a0b\u4ee5\u53ca\u91c7\u96c6\u8bb8\u53ef\u3001\u4fdd\u85cf\u6d3b\u52a8\u7684\u5177\u4f53\u8303\u56f4\u7b49\uff0c\u65e8\u5728\u8fdb\u4e00\u6b65\u63d0\u5347\u6211\u56fd\u4eba\u7c7b\u8d44\u6e90\u7ba1\u7406\u6548\u80fd\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.most.gov.cn\/tztg\/202203\/t20220322_179904.html<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u79d1\u6280\u90e8\u53d1\u5e03\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u884c\u653f\u8bb8\u53ef\u4e8b\u98792022\u5e74 \u7b2c5\u6279\u5ba1\u6279\u7ed3\u679c<\/div>\n
2022\u5e743\u670822\u65e5\uff0c\u79d1\u6280\u90e8\u53d1\u5e03\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u884c\u653f\u8bb8\u53ef\u4e8b\u98792022\u5e74 \u7b2c5\u6279\u5ba1\u6279\u7ed3\u679c\uff0c\u5217\u4e3e\u4ee3\u8868\u6027\u9879\u76ee\u5982\u4e0b\uff1a<\/div>\n
\u4eba\u5fae\u536b\u661f\u4e0d\u7a33\u5b9a\u6027\uff08MSI\uff09\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08\u8367\u5149PCR-\u6bdb\u7ec6\u7ba1\u7535\u6cf3\u6cd5\uff09\u4e34\u5e8a\u8bd5\u9a8c\u2014\u2014\u5357\u4eac\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u9f13\u697c\u533b\u9662\u3001\u8fc8\u6770\u8f6c\u5316\u533b\u5b66\u3001\u751f\u5de5\u5065\u5eb7\u3001\u535a\u5965\u533b\u5b66<\/div>\n
\u4e2d\u56fd\u5375\u5de2\u764c\u60a3\u8005HRR\u7a81\u53d8\u8c31\u548cHRD\u72b6\u6001\u4e0ePARPi\u7597\u6548\u76f8\u5173\u6027\u7814\u7a76\u2014\u2014\u4e2d\u5c71\u5927\u5b66\u5b59\u9038\u4ed9\u7eaa\u5ff5\u533b\u9662\u3001\u827e\u5fb7\u751f\u7269<\/div>\n
\u4eba\u4e73\u5934\u72b6\u7624\u75c5\u6bd2\uff08HPV\uff09\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08PCR\u8367\u5149\u6cd5\uff09\uff08\u4ea7\u54c1\u82f1\u6587\u540d\uff1acobas\u00aeHPV\uff09HPV\u6838\u9178\u68c0\u6d4b\u51c6\u786e\u6027\u9a8c\u8bc1\u4e34\u5e8a\u8bd5\u9a8c\u2014\u2014\u6d59\u6c5f\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u5987\u4ea7\u79d1\u533b\u9662\u3001\u6d59\u6c5f\u7701\u5987\u5973\u533b\u9662\u3001\u6d59\u6c5f\u7701\u5987\u5973\u4fdd\u5065\u9662\u3001\u7f57\u6c0f\u8bca\u65ad\u3001\u89c2\u5408\u533b\u5b66<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/fuwu.most.gov.cn\/html\/tztg\/xzxkzx\/20220322\/123124204.html<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u56fd\u5bb6\u7cbe\u51c6\u533b\u5b66\u4ea7\u4e1a\u521b\u65b0\u4e2d\u5fc3\u5728\u6210\u90fd\u63ed\u724c<\/div>\n
2022\u5e743\u670823\u65e5\uff0c\u7531\u56db\u5ddd\u5927\u5b66\u534e\u897f\u533b\u9662\u7275\u5934\u7ec4\u5efa\u7684\u56fd\u5bb6\u7cbe\u51c6\u533b\u5b66\u4ea7\u4e1a\u521b\u65b0\u4e2d\u5fc3\u5728\u6210\u90fd\u5929\u5e9c\u56fd\u9645\u751f\u7269\u57ce\u63ed\u724c\u3002\u8be5\u4e2d\u5fc3\u8054\u5408\u4e0a\u6d77\u745e\u91d1\u3001\u6e05\u534e\u5927\u5b66\u3001\u4e0a\u836f\u96c6\u56e2\u3001\u534e\u5927\u57fa\u56e0\u7b49\u5168\u56fd\u591a\u5bb6\u5171\u5efa\u5355\u4f4d\u7ec4\u5efa\uff0c\u662f\u6211\u56fd\u5728\u751f\u7269\u533b\u836f\u9886\u57df\u5e03\u5c40\u5efa\u8bbe\u7684\u7b2c\u4e00\u4e2a\u4ea7\u4e1a\u521b\u65b0\u4e2d\u5fc3\uff0c\u4e5f\u662f\u76ee\u524d\u7cbe\u51c6\u533b\u5b66\u65b9\u5411\u552f\u4e00\u7684\u4ea7\u4e1a\u521b\u65b0\u4e2d\u5fc3\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u7528\u4e8e\u6cbb\u7597\u795e\u7ecf\u6bcd\u7ec6\u80de\u7624\u7684MDM2-p53\u6291\u5236\u5242\u83b7FDA\u513f\u7ae5\u7f55\u89c1\u75c5\u8d44\u683c\u8ba4\u8bc1<\/div>\n
\u8fd1\u65e5\uff0c\u4e9a\u76db\u533b\u836f\u5ba3\u5e03\u5728\u7814\u539f\u521b\u65b0\u836fMDM2-p53\u6291\u5236\u5242APG-115\uff08alrizomadlin\uff09\u83b7\u5f97\u7f8e\u56fd\u98df\u54c1\u548c\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08FDA\uff09\u6388\u4e88\u7684\u513f\u7ae5\u7f55\u89c1\u75c5\u8d44\u683c\u8ba4\u8bc1\uff0c\u7528\u4e8e\u6cbb\u7597\u795e\u7ecf\u6bcd\u7ec6\u80de\u7624\u3002\u81f3\u6b64\uff0cAPG-115\u5df2\u83b7\u5f97FDA\u6388\u4e88\u7684\u516d\u9879\u5b64\u513f\u836f\u8d44\u683c\u8ba4\u8bc1\uff08ODD\uff09\u3001\u4e24\u9879RPD\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4f53\u7ec6\u80de\u8bf1\u5bfc\u51fa\u5168\u80fd\u5e72\u7ec6\u80de\uff0c\u6bd4\u8bfa\u5956\u8bf1\u5bfc\u7684\u5e72\u7ec6\u80de\u63d0\u524d3\u5929<\/div>\n
\u8fd1\u65e5\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u3001\u6df1\u5733\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u7b49\u673a\u6784\u7684\u7814\u7a76\u8005\u5728Nature\u4e0a\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u4ed6\u4eec\u901a\u8fc7\u4f53\u7ec6\u80de\u8bf1\u5bfc\u57f9\u517b\u51fa\u4e86\u7c7b\u4f3c\u53d7\u7cbe\u5375\u53d1\u80b23\u5929\u72b6\u6001\u7684\u4eba\u7c7b\u5168\u80fd\u5e72\u7ec6\u80de\uff0c\u5bf9\u89e3\u51b3\u5668\u5b98\u77ed\u7f3a\u3001\u5f02\u4f53\u548c\u5f02\u79cd\u79fb\u690d\u6392\u65a5\u53cd\u5e94\u7b49\u5177\u6709\u91cd\u5927\u610f\u4e49\u3002\u8fd9\u662f\u7ee72012\u5e74\u65e5\u672c\u79d1\u5b66\u5bb6\u5c71\u4e2d\u4f38\u5f25\u8bf1\u5bfc\u5f97\u5230\u591a\u80fd\u5e72\u7ec6\u80de\uff08\u76f8\u5f53\u4e8e\u662f\u53d7\u7cbe\u5375\u53d1\u80b25-6\u5929\u65f6\u7684\u72b6\u6001\uff09\u540e\uff0c\u518d\u751f\u533b\u5b66\u9886\u57df\u7684\u53c8\u4e00\u98a0\u8986\u6027\u7a81\u7834\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41586-022-04625-0<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4e2d\u56fd\u79d1\u7814\u56e2\u961f\u53d1\u73b0\u7389\u7c73\u3001\u6c34\u7a3b\u201c\u9ad8\u4ea7\u57fa\u56e0\u201d<\/div>\n
2022\u5e743\u670825\u65e5\uff0c\u4e2d\u56fd\u519c\u4e1a\u5927\u5b66\u56e2\u961f\u4e0e\u534e\u4e2d\u519c\u4e1a\u5927\u5b66\u56e2\u961f\u5728Science\u4e0a\u53d1\u8868\u7814\u7a76\u6210\u679c\uff0c\u4ed6\u4eec\u53d1\u73b0\uff0c\u7389\u7c73KRN2\u548c\u6c34\u7a3bOsKRN2\u5c5e\u4e8e\u540c\u6e90\u57fa\u56e0\uff0c\u53d7\u5230\u8d8b\u540c\u9009\u62e9\uff0c\u5e76\u901a\u8fc7\u76f8\u4f3c\u7684\u9014\u5f84\u8c03\u63a7\u7389\u7c73\u548c\u6c34\u7a3b\u7684\u4ea7\u91cf\uff0c\u7389\u7c73KRN2\u6572\u9664\u7cfb\u548c\u6c34\u7a3bOsKRN2\u6572\u9664\u7cfb\u53ef\u5206\u522b\u63d0\u9ad810%\u7684\u7389\u7c73\u4ea7\u91cf\u548c8%\u7684\u6c34\u7a3b\u4ea7\u91cf\uff0c\u5e76\u4e14\u5bf9\u5176\u4ed6\u519c\u827a\u6027\u72b6\u6ca1\u6709\u660e\u663e\u7684\u8d1f\u9762\u5f71\u54cd\uff0c\u5c55\u73b0\u4e86\u5de8\u5927\u7684\u5e94\u7528\u6f5c\u529b\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.science.org\/doi\/10.1126\/science.abg7985<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u9488\u5bf91\u578b\u810a\u9ad3\u578b\u808c\u840e\u7f29\u7684\u57fa\u56e0\u6cbb\u7597\u836f\u7269\u4e34\u5e8a\u7814\u7a76\u9996\u4f8b\u53d7\u8bd5\u8005\u5b8c\u6210\u7ed9\u836f\u5e76\u987a\u5229\u51fa\u9662<\/div>\n
2022\u5e743\u670825\u65e5\uff0c\u5609\u56e0\u751f\u7269\u81ea\u4e3b\u7814\u53d1\u7684\u6cbb\u75971\u578b\u810a\u9ad3\u578b\u808c\u840e\u7f29\u7684\u57fa\u56e0\u6cbb\u7597\u836f\u7269EXG001-307\u6ce8\u5c04\u6db2\u5728\u6d59\u6c5f\u5927\u5b66\u533b\u5b66\u9662\u9644\u5c5e\u513f\u7ae5\u533b\u9662\u5f00\u5c55\u7684\u4e34\u5e8a\u7814\u7a76\u5b8c\u6210\u9996\u4f8b\u53d7\u8bd5\u8005\u7ed9\u836f\uff0c\u5b89\u5168\u6027\u53ca\u8010\u836f\u6027\u5747\u8868\u73b0\u826f\u597d\uff0c\u63a5\u53d7\u6cbb\u7597\u7684\u60a3\u513f\u5728\u4e34\u5e8a\u533b\u62a4\u4eba\u5458\u7684\u7cbe\u5fc3\u6cbb\u7597\u4e0e\u62a4\u7406\u4e0b\uff0c\u5df2\u987a\u5229\u51fa\u9662\u3002<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u53d1\u5c55<\/div>\n
\u2756\u00a0\u8bca\u65ad\u68c0\u6d4b\u670d\u52a1\u5546\u4e91\u5eb7\u96c6\u56e2\u5411\u6e2f\u4ea4\u6240\u4e3b\u677f\u63d0\u4ea4\u4e0a\u5e02\u7533\u8bf7<\/div>\n
\u8fd1\u65e5\uff0c\u4e91\u5eb7\u96c6\u56e2\u6709\u9650\u516c\u53f8\u5411\u6e2f\u4ea4\u6240\u4e3b\u677f\u63d0\u4ea4\u4e0a\u5e02\u7533\u8bf7\uff0c\u62db\u94f6\u56fd\u9645\u548c\u6d66\u94f6\u56fd\u9645\u4e3a\u8054\u5e2d\u4fdd\u8350\u4eba\u3002\u4e91\u5eb7\u96c6\u56e2\u4e3b\u8981\u4e3a\u533b\u7597\u673a\u6784\u63d0\u4f9b\u5168\u5957\u7684\u8bca\u65ad\u68c0\u6d4b\u670d\u52a1\u30022020\u5e74\uff0c\u6309\u6536\u76ca\u8ba1\uff0c\u4e91\u5eb7\u96c6\u56e2\u6210\u4e3a\u4e2d\u56fd\u533b\u5b66\u8fd0\u8425\u670d\u52a1\u5e02\u573a\u7684\u7b2c\u4e94\u5927\u516c\u53f8\uff0c\u5e02\u573a\u4efd\u989d\u5360\u52303.7%\u3002\u4e91\u5eb7\u96c6\u56e2\u8ba1\u5212\u5c06\u52df\u5f97\u8d44\u91d1\u7528\u4e8e\u6269\u5927\u6df1\u5316\u516c\u53f8\u533b\u8054\u4f53\u7f51\u7edc\u3001\u63d0\u5347\u516c\u53f8\u533b\u5b66\u8fd0\u8425\u670d\u52a1\u63d0\u4f9b\u5546\u7684\u8425\u8fd0\u80fd\u529b\u3001\u6269\u5927\u8bca\u65ad\u80fd\u529b\u7b49\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u57fa\u56e0\u6cbb\u7597CDMO\u516c\u53f8\u548c\u5143\u751f\u7269\u79d1\u521b\u677f\u4e0a\u5e02<\/div>\n
2022\u5e743\u670822\u65e5\uff0c\u548c\u5143\u751f\u7269\u5728\u4e0a\u6d77\u8bc1\u5238\u4ea4\u6613\u6240\u79d1\u521b\u677f\u6b63\u5f0f\u6302\u724c\u4e0a\u5e02\u3002\u548c\u5143\u751f\u7269\u4e13\u6ce8\u4e8e\u4e3a\u57fa\u56e0\u6cbb\u7597\u7684\u57fa\u7840\u7814\u7a76\u63d0\u4f9b\u57fa\u56e0\u6cbb\u7597\u8f7d\u4f53\u7814\u5236\u3001\u57fa\u56e0\u529f\u80fd\u7814\u7a76\u7b49CRO\u670d\u52a1\uff0c\u4ee5\u53ca\u4e3a\u57fa\u56e0\u836f\u7269\u7684\u7814\u53d1\u63d0\u4f9bIND-CMC\u836f\u5b66\u7814\u7a76\u3001\u4e34\u5e8a\u6837\u54c1GMP\u751f\u4ea7\u7b49CDMO\u670d\u52a1\u3002\u672c\u6b21\u52df\u96c6\u8d44\u91d1\u5c06\u7528\u4e8e\u548c\u5143\u667a\u9020\u7cbe\u51c6\u533b\u7597\u4ea7\u4e1a\u57fa\u5730\u5efa\u8bbe\u9879\u76ee\u548c\u8865\u5145\u6d41\u52a8\u8d44\u91d1\uff0c\u8fdb\u4e00\u6b65\u52a0\u5f3a\u57fa\u56e0\u6cbb\u7597\u7efc\u5408\u670d\u52a1\u5e73\u53f0\u4f18\u52bf\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u4f55\u6c0f\u773c\u79d1\u6b63\u5f0f\u767b\u9646\u521b\u4e1a\u677f\uff0c\u672a\u6765\u5c06\u5e03\u5c40\u57fa\u56e0\u68c0\u6d4b<\/div>\n
2022\u5e743\u670822\u65e5\uff0c\u4f55\u6c0f\u773c\u79d1\u6210\u529f\u767b\u9646\u6df1\u4ea4\u6240\u521b\u4e1a\u677f\u3002\u4f55\u6c0f\u773c\u79d1\u96c6\u533b\u6559\u7814\u4e8e\u4e00\u4f53\uff0c\u81f4\u529b\u4e8e\u5168\u751f\u547d\u5468\u671f\u773c\u5065\u5eb7\u7ba1\u7406\uff0c\u5c06\u4f9d\u62585G\u3001\u7269\u8054\u7f51\u3001\u57fa\u56e0\u6280\u672f\u548c\u4eba\u5de5\u667a\u80fd\u7b49\u521b\u65b0\u79d1\u6280\u624b\u6bb5\uff0c\u4e0d\u65ad\u63d0\u5347\u667a\u80fd\u5206\u6790\u3001\u8fdc\u7a0b\u533b\u7597\u548c\u5065\u5eb7\u7ba1\u7406\u7b49\u529f\u80fd\uff0c\u8ba9\u60a3\u8005\u4eab\u53d7\u66f4\u4f18\u8d28\u3001\u66f4\u591a\u5143\u5316\u7684\u773c\u5065\u5eb7\u670d\u52a1\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u8bfa\u8f89\u5065\u5eb72021\u5168\u5e74\u603b\u6536\u5165\u540c\u6bd4\u589e\u957f\u8d85200%<\/div>\n
2022\u5e743\u670818\u65e5\uff0c\u764c\u75c7\u65e9\u7b5b\u4f01\u4e1a\u8bfa\u8f89\u5065\u5eb7\u53d1\u5e032021\u5e74\u5ea6\u62a5\u544a\u3002\u8bfa\u8f89\u5065\u5eb7\u5168\u5e74\u8425\u65362.1\u4ebf\u5143\uff0c\u540c\u6bd4\u589e\u957f201.5%\uff1b\u5e74\u5185\u4e8f\u635f\u51c0\u989d\u7ea630.859\u4ebf\u5143\uff0c\u7ecf\u8c03\u6574\u540e\u51c0\u4e8f\u635f\u7ea62.858\u4ebf\u5143\u3002\u80a0\u764c\u65e9\u7b5b\u4ea7\u54c1\u5e38\u536b\u6e05\u548c\u5657\u5657\u7ba1\u5206\u522b\u5b9e\u73b0\u6536\u51659720\u4e07\u5143\u3001\u540c\u6bd4\u589e\u957f159%\uff1b\u6536\u51651.2\u4ebf\u5143\u3001\u540c\u6bd4\u589e\u957f263%\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u71c3\u77f3\u533b\u5b662021\u5168\u5e74\u603b\u6536\u5165\u540c\u6bd4\u589e\u957f18.1%<\/div>\n
2022\u5e743\u670822\u65e5\uff0c\u71c3\u77f3\u533b\u5b66\u53d1\u5e032021\u5e74\u5ea6\u62a5\u544a\u3002\u71c3\u77f3\u533b\u5b66\u5168\u5e74\u8425\u65365.079\u4ebf\u5143\uff0c\u540c\u6bd4\u589e\u957f18.1%\u3002\u5f52\u5c5e\u4e8e\u6bcd\u516c\u53f8\u666e\u901a\u80a1\u80a1\u4e1c\u51c0\u5229\u6da6\u4e3a-7.97\u4ebf\u4eba\u6c11\u5e01\u5143\uff0c\u540c\u6bd4\u4e0b\u964d68.82%\u3002\u516c\u53f82022\u5e74\u5168\u5e74\u7684\u6536\u5165\u9884\u8ba1\u7ea6\u4e3a6.2\u4ebf\u5143\uff0c\u76f8\u6bd4\u4e8e2021\u5e74\u9884\u8ba1\u589e\u957f\u7ea622%\u3002<\/div>\n
\u00a0<\/div>\n
\u6295\u878d\u8d44<\/div>\n
\u2756\u00a0siRNA\u836f\u7269\u7814\u53d1\u5546\u8236\u671b\u5236\u836f\u5b8c\u6210\u8d854\u4ebf\u5143A\u8f6e\u878d\u8d44<\/div>\n
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\u00a0<\/div>\n
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\u8fd1\u65e5\uff0c\u8fb0\u5149\u533b\u7597\u5b8c\u6210\u6570\u5343\u4e07\u5143Pre-A\u8f6e\u878d\u8d44\uff0c\u7531\u6069\u7136\u521b\u6295\u65d7\u4e0b\u5357\u4eac\u6c5f\u5317\u79d1\u6295\u57fa\u91d1\u5176\u745e\u4f51\u5eb7\u72ec\u5bb6\u6295\u8d44\uff0c\u878d\u8d44\u8d44\u91d1\u5c06\u7528\u4e8e\u5b50\u516c\u53f8\u80e1\u66fc\u667a\u9020\u7684\u5168\u81ea\u52a8\u591a\u91cd\u6d41\u5f0f\u8367\u5149\u68c0\u6d4b\u5e73\u53f0\u53ca\u914d\u5957\u8bd5\u5242\u7684\u6ce8\u518c\u7533\u62a5\u3001\u65b0\u751f\u4ea7\u57fa\u5730\u7684\u5efa\u8bbe\u53ca\u7814\u53d1\u56e2\u961f\u7684\u6269\u5145\u3002<\/div>\n
\u00a0<\/div>\n
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2022\u5e743\u670821\u65e5\uff0c\u9f50\u79be\u751f\u79d1\u5b8c\u6210\u7531\u674f\u6cfd\u8d44\u672c\u72ec\u5bb6\u9886\u6295\u7684\u903e\u4ebf\u5143\u4eba\u6c11\u5e01\u79cd\u5b50\u8f6e\u878d\u8d44\uff0c\u672c\u8f6e\u878d\u8d44\u6240\u52df\u96c6\u8d44\u91d1\u5c06\u4e3b\u8981\u7528\u4e8e\u516c\u53f8\u65b0\u4e00\u4ee3\u57fa\u56e0\u7f16\u8f91\u5de5\u5177\u7684\u5f00\u53d1\uff0c\u4ee5\u53ca\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u5728\u751f\u7269\u80b2\u79cd\u7b49\u5404\u4ea7\u4e1a\u65b9\u5411\u7684\u5e94\u7528\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u764c\u75c7\u8bca\u65ad\u516c\u53f8 Yemaachi \u5b8c\u6210 300 \u4e07\u7f8e\u5143\u79cd\u5b50\u8f6e\u878d\u8d44<\/div>\n
2022\u5e743\u670821\u65e5\uff0cYemaachi\u5b8c\u6210 300 \u4e07\u7f8e\u5143\u79cd\u5b50\u8f6e\u878d\u8d44\uff0c\u7531 V8 Capital \u9886\u6295\uff0c\u73b0\u6709\u6295\u8d44\u8005\u5305\u62ecY Combinator\u3001\u817e\u8baf\u7b49\u3002Yemaachi\u5c06\u5229\u7528\u8fd9\u7b14\u8d44\u91d1\u8fdb\u4e00\u6b65\u5f00\u53d1\u5176\u6cdb\u57fa\u56e0\u7ec4\u548c\u4e34\u5e8a\u77e5\u8bc6\u5e93\u3002<\/div>\n
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2022\u5e743\u670822\u65e5\uff0cPreludeDx\u5ba3\u5e03\u5b8c\u6210 2000 \u4e07\u7f8e\u5143\u7684\u878d\u8d44\uff0c\u7531 Evidity Health Capital \u7275\u5934\uff0c\u8fd9\u7b14\u8d44\u91d1\u5c06\u7528\u4e8e\u8fdb\u4e00\u6b65\u63a8\u8fdb PreludeDx \u7684 DCISionRT \u4e73\u817a\u764c\u98ce\u9669\u8bc4\u4f30\u6d4b\u8bd5\u7684\u5546\u4e1a\u5e02\u573a\u6269\u5f20\uff0c\u5e76\u7ee7\u7eed\u5f00\u53d1\u8be5\u516c\u53f8\u9488\u5bf9\u65e9\u671f\u764c\u75c7\u7684\u7cbe\u5bc6\u653e\u5c04\u57fa\u56e0\u7ec4\u5b66\u5e73\u53f0\u3002<\/div>\n
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2022\u5e743\u670822\u65e5\uff0cNucleai\u5b8c\u6210 3300 \u4e07\u7f8e\u5143 B \u8f6e\u878d\u8d44\uff0c Section 32 \u548c\u8d5b\u8bfa\u83f2\u98ce\u9669\u6295\u8d44\u516c\u53f8\u8054\u5408\u9886\u6295\uff0c\u5176\u4ed6\u6295\u8d44\u8005\u5305\u62ecDebiopharm\u3001Vertex Ventures\u7b49\u3002\u8be5\u516c\u53f8\u7684\u5e73\u53f0\u901a\u8fc7\u5206\u6790\u5927\u578b\u7ec4\u7ec7\u56fe\u50cf\u6570\u636e\u96c6\u6765\u6a21\u62df\u80bf\u7624\u548c\u60a3\u8005\u514d\u75ab\u7cfb\u7edf\u7684\u7a7a\u95f4\u7279\u5f81\uff0c\u5e2e\u52a9\u9884\u6d4b\u60a3\u8005\u5bf9\u5404\u79cd\u764c\u75c7\u7597\u6cd5\u7684\u53cd\u5e94\u3002\u672c\u8f6e\u878d\u8d44\u5c06\u7528\u4e8e\u63a8\u8fdb\u5176\u7a7a\u95f4\u5206\u6790\u5e73\u53f0\u7814\u53d1\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u57fa\u56e0\u68c0\u6d4b\u8bbe\u5907\u7814\u53d1\u5546 InnoSign \u5b8c\u6210800\u4e07\u7f8e\u5143 A \u8f6e\u878d\u8d44<\/div>\n
2022\u5e743\u670822\u65e5\uff0cInnoSign\u5ba3\u5e03\u5b8c\u6210800\u4e07\u7f8e\u5143 A \u8f6e\u878d\u8d44\uff0c\u672c\u8f6e\u6295\u8d44\u8005\u5305\u62ec Casdin Capital\u3001Life Science Angels\u7b49\uff0c\u6240\u5f97\u6b3e\u9879\u5c06\u7528\u4e8e\u8d44\u52a9\u8be5\u516c\u53f8\u4ece\u7687\u5bb6\u98de\u5229\u6d66\u5206\u62c6\uff0c\u4ee5\u7ec4\u5efa\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u4f18\u5316PCR\u8bbe\u5907\u7684\u6280\u672f\u7684\u72ec\u7acb\u516c\u53f8\u3002<\/div>\n
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\u53c2\u8003\u4fe1\u606f>>https:\/\/www.intlpagasia.org\/2022\/<\/div>\n
\u6587\u7ae0 | \u57fa\u56e0\u6167\u00a0\u00a0<\/div>\n
\u7f16\u8f91 | Kathy\u00a0<\/div>\n\n
\n
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