{"id":8735,"date":"2022-05-02T08:00:00","date_gmt":"2022-05-02T00:00:00","guid":{"rendered":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/05\/02\/535556\/"},"modified":"2026-04-01T11:52:28","modified_gmt":"2026-04-01T03:52:28","slug":"535556","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/05\/02\/535556\/","title":{"rendered":"\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5\uff08187\u671f) | \u97a0\u666f\u6708\u56e2\u961f\u5c06\u53d1\u5e03\u56fd\u4ea7\u6d4b\u5e8f\u4eea\u65b0\u54c1\uff1bQ1\u884c\u4e1a\u6295\u878d\u8d44\u8fd150\u4ebf\u5143"},"content":{"rendered":"

<\/p>\n

\u805a\u7126<\/div>\n
\u4e00\u5468\u70ed\u70b9<\/div>\n
1 \u97a0\u666f\u6708\u6559\u6388\u9886\u8854\u56e2\u961f\u5c06\u53d1\u5e03\u9ad8\u901a\u91cf\u57fa\u56e0\u6d4b\u5e8f\u4eea<\/div>\n
2 Q1\u517115\u5bb6\u57fa\u56e0\u4f01\u4e1a\u878d\u8d44\u603b\u8ba1\u8fd150\u4ebf\u5143\u4eba\u6c11\u5e01<\/div>\n
3 \u97e9\u56fd\u57fa\u7840\u79d1\u5b66\u6240\u5f00\u53d1\u65b0\u578b\u57fa\u56e0\u7f16\u8f91\u5e73\u53f0<\/div>\n
4 Illumina\u4e0eJanssen\u00a0Biotech\u5408\u4f5c\u5f00\u53d1\u7cbe\u51c6\u836f\u7269<\/div>\n
5 \u6211\u56fd\u9996\u6b3e\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\u6ce8\u5c04\u6db2\u83b7\u9ed8\u793a\u8bb8\u53ef<\/div>\n
6 10\u5e74\u6295\u5165100\u4ebf\u5230\u751f\u7269\u4e0e\u533b\u5b66\u79d1\u5b66\u3001\u6570\u5b66\u4e0e\u7269\u8d28\u79d1\u5b66\u57fa\u7840\u7814\u7a76<\/div>\n
\u2026\u2026\uff08\u66f4\u591a\u8be6\u60c5\u89c1\u57fa\u56e0\u6167\u6bcf\u5468GeneMail\uff09<\/div>\n
\u00a0<\/div>\n
\u5934\u6761\u8d44\u8baf<\/div>\n
\u2756\u00a0\u97a0\u666f\u6708\u6559\u6388\u9886\u8854\u56e2\u961f\u5c06\u53d1\u5e03\u9ad8\u901a\u91cf\u57fa\u56e0\u6d4b\u5e8f\u4eea<\/div>\n
2022\u5e744\u670830\u65e5\uff0c\u57fa\u56e0\u6167\u83b7\u6089\uff0c\u54e5\u4f26\u6bd4\u4e9a\u5927\u5b66\u57fa\u56e0\u6280\u672f\u4e2d\u5fc3\u4e3b\u4efb\u97a0\u666f\u6708\u6559\u6388\u9886\u8854\u7684\u56e2\u961f\u5c06\u53d1\u5e03\u5355\u8272\u8367\u5149\u9ad8\u901a\u91cf\u57fa\u56e0\u6d4b\u5e8f\u4eea\u3002\u53d1\u5e03\u4f1a\u5c06\u4e8e2022\u5e745\u67089\u65e5\u5728\u91cd\u5e86\u53ec\u5f00\u3002\u6b64\u4ea7\u54c1\u4f9d\u6258\u7684\u673a\u6784\u4e3a\u6df1\u5733\u94ed\u6bc5\u667a\u9020\u79d1\u6280\u6709\u9650\u516c\u53f8\uff0c2018\u5e74\u6210\u7acb\u4e8e\u6df1\u5733\uff0c\u7531\u97a0\u666f\u6708\u6559\u6388\u4e0e\u4f0d\u5efa\u535a\u58eb\u7b49\u4eba\u8054\u5408\u521b\u7acb\uff0c\u76ee\u524d\u5df2\u5b8c\u6210B\u8f6e\u6295\u8d44\uff0c\u80a1\u4e1c\u5305\u62ec\u4f0d\u5efa\u3001\u9648\u946b\u3001\u5434\u91d1\u96e8\u3001\u59dc\u6d77\u821f\u548c\u5357\u4eac\u949b\u548c\u96ea\u6749\u521b\u4e1a\u6295\u8d44\u5408\u4f19\u4f01\u4e1a\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a010\u5e74\u6295\u5165100\u4ebf\u5230\u751f\u7269\u4e0e\u533b\u5b66\u79d1\u5b66\u3001\u6570\u5b66\u4e0e\u7269\u8d28\u79d1\u5b66\u57fa\u7840\u7814\u7a76<\/div>\n
2022\u5e744\u670830\u65e5\uff0c\u5728\u56fd\u5bb6\u6709\u5173\u90e8\u95e8\u7684\u6307\u5bfc\u4e0b\uff0c\u201c\u65b0\u57fa\u77f3\u7814\u7a76\u5458\u9879\u76ee\u201d\u7531\u79d1\u5b66\u5bb6\u4e3b\u5bfc\uff0c\u817e\u8baf\u516c\u53f8\u5c06\u5728\u672a\u676510\u5e74\u6295\u5165100\u4ebf\u5143\u4f5c\u4e3a\u652f\u6301\u3002\u8be5\u9879\u76ee\u5c06\u8bbe\u7f6e\u201c\u6570\u5b66\u4e0e\u7269\u8d28\u79d1\u5b66\u201d\u3001\u201c\u751f\u7269\u4e0e\u533b\u5b66\u79d1\u5b66\u201d\u4e24\u5927\u9886\u57df\uff0c\u652f\u6301\u5728\u4e2d\u56fd\u5185\u5730\u53ca\u6e2f\u6fb3\u5730\u533a\u5168\u804c\u5de5\u4f5c\u7684\u79d1\u5b66\u5bb6\uff0c\u63a2\u7d22\u6c38\u7eed\u8fd0\u8425\u6a21\u5f0f\uff0c\u957f\u4e45\u652f\u6301\u57fa\u7840\u7814\u7a76\u3002\uff08\u70b9\u51fb\u67e5\u770b\u8be6\u60c5\uff09<\/a><\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u97e9\u56fd\u57fa\u7840\u79d1\u5b66\u6240\u5f00\u53d1\u65b0\u578b\u57fa\u56e0\u7f16\u8f91\u5e73\u53f0<\/div>\n
2022\u5e744\u670825\u65e5\uff0c\u97e9\u56fd\u57fa\u7840\u79d1\u5b66\u7814\u7a76\u6240\u57fa\u56e0\u7ec4\u5de5\u7a0b\u4e2d\u5fc3\u5728Cell\u00a0\u520a\u6587\u79f0\uff0c\u4ed6\u4eec\u5f00\u53d1\u4e86\u4e00\u79cd\u540d\u4e3a\u8f6c\u5f55\u6fc0\u6d3b\u56e0\u5b50\u6837\u6548\u5e94\u7269\u76f8\u5173\u8131\u6c22\u9176\uff08transcription activator-like effector-linked deaminases\uff0c\u4ee5\u4e0b\u7f29\u5199\u4e3aTALED\uff09\u7684\u65b0\u578b\u57fa\u56e0\u7f16\u8f91\u5e73\u53f0\u3002\u7ebf\u7c92\u4f53DNA\u7f16\u8f91\u4e00\u76f4\u4ee5\u6765\u90fd\u662f\u57fa\u56e0\u7f16\u8f91\u9886\u57df\u7684\u96be\u9898\uff0c\u800c\u8be5\u5e73\u53f0\u9996\u6b21\u5b9e\u73b0\u4e86\u5728\u7ebf\u7c92\u4f53\u4e2d\u7cbe\u786e\u8fdb\u884cA\u78b1\u57fa\u5230G\u78b1\u57fa\u8f6c\u6362\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(22)00389-0#fx1<\/div>\n
\u3010\u77e5\u8bc6\u5361\u7247\u3011<\/div>\n\n
\n
\"RmFicvQBAkgBbGQpoDArPEvgLrIsQFzqam1TR4gB6aT0TfWibicrFliaANrfaFqKrLRzbfOgAib011uztDW5c9PK0LQ\"\/<\/figure><\/div>\n\n

\u2756\u00a0\u6211\u56fd\u9996\u6b3e\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\u6ce8\u5c04\u6db2\u83b7\u9ed8\u793a\u8bb8\u53ef<\/p>\n

2022\u5e744\u670826\u65e5\uff0c\u5448\u8bfa\u518d\u751f\u533b\u5b66\u79d1\u6280\uff08\u73e0\u6d77\u6a2a\u7434\u65b0\u533a\uff09\u6709\u9650\u516c\u53f8\u7684\u201c\u5f02\u4f53\u5185\u76ae\u7956\u7ec6\u80de\uff08EPCs\uff09\u6ce8\u5c04\u6db2\u201d\uff08\u4ee3\u53f7ALF201\uff09\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u83b7\u6279\uff08\u53d7\u7406\u53f7\uff1aCXSL2200090\uff09\uff0c\u62df\u7528\u4e8e\u6cbb\u7597\u5927\u52a8\u8109\u7ca5\u6837\u786c\u5316\u578b\u6025\u6027\u7f3a\u8840\u6027\u5352\u4e2d\u3002\u8fd9\u662f\u56fd\u5185\u9996\u6b3e\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u4e34\u5e8a\u9ed8\u793a\u8bb8\u53ef\u7684\u8bf1\u5bfc\u6027\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\u6765\u6e90\u7ec6\u80de\u836f\u7269\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cde.org.cn\/main\/xxgk\/listpage\/9f9c74c73e0f8f56a8bfbc646055026d<\/div>\n
\u5b8f\u89c2\u73af\u5883<\/div>\n

\u2756\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u7684\u7b2c\u4e09\u4ee3ALK\u6291\u5236\u5242\u83b7\u6279<\/p>\n

2022\u5e744\u670829\u65e5\uff0c\u8f89\u745e\u516c\u53f8\u7684\u6d1b\u62c9\u66ff\u5c3c\uff08lorlatinib\uff09\u7247\u83b7\u56fd\u5bb6\u836f\u76d1\u5c40\u6279\u51c6\u3002\u6d1b\u62c9\u66ff\u5c3c\u662f\u4e00\u6b3e\u7b2c\u4e09\u4ee3ALK\u6291\u5236\u5242\uff0c\u672c\u6b21\u83b7\u6279\u7528\u4e8e\u6cbb\u7597ALK\u9633\u6027\u5c40\u90e8\u665a\u671f\u6216\u8f6c\u79fb\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u3002\u8be5\u836f\u80fd\u6291\u5236\u5bf9\u5176\u5b83ALK\u6291\u5236\u5242\u8010\u836f\u7684ALK\u57fa\u56e0\u7a81\u53d8\uff0c\u53ef\u6cbb\u7597\u8111\u8f6c\u79fb\u7624\u3002\u6d1b\u62c9\u66ff\u5c3c\u66fe\u83b7FDA\u7a81\u7834\u6027\u7597\u6cd5\u8ba4\u5b9a\u3001\u4f18\u5148\u5ba1\u8bc4\u8d44\u683c\uff0c\u4e4b\u540e\u8fd8\u83b7\u6279\u6cbb\u7597\u7ecf\u6cbb\u7684ALK\u9633\u6027\u8f6c\u79fb\u6027NSCLC\u3001\u4ee5\u53ca\u4e00\u7ebf\u6cbb\u7597ALK\u9633\u6027NSCLC\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/endpts.com\/vivo-capital-pitches-60m-to-bring-arrowheads-rnai-meds-to-china-via-joint-venture\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u6211\u56fd\u7b2c30\u4e2a\u6297\u539f\u68c0\u6d4b\u8bd5\u5242\u83b7\u6279<\/div>\n
2022\u5e744\u670827\u65e5\uff0c\u56fd\u5bb6\u836f\u76d1\u5c40\u518d\u6279\u51c6\u901a\u8fc7\u4e00\u6b3e\u65b0\u51a0\u6297\u539f\u68c0\u6d4b\u8bd5\u5242\uff0c\u622a\u81f34\u670827\u65e5\uff0c\u56fd\u5bb6\u836f\u76d1\u5c40\u5df2\u6279\u51c630\u4e2a\u65b0\u51a0\u75c5\u6bd2\u6297\u539f\u68c0\u6d4b\u8bd5\u5242\u4ea7\u54c1\u3002<\/div>\n\n
\n
\"0?wx_fmt=jpeg\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u622a\u81f32022\u5e744\u670827\u65e5\uff0c<\/div>\n
NMPA\u6279\u51c6\u7684\u65b0\u51a0\u75c5\u6bd2\u6297\u539f\u68c0\u6d4b\u8bd5\u5242\u4ea7\u54c1\u3002<\/div>\n
\uff08\u6765\u6e90\/NMPA\u5b98\u7f51\uff09<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.gov.cn\/xinwen\/2022-04\/27\/content_5687567.htm<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0FDA\u5206\u7c7b\u7edf\u8ba1400\u4f59\u4e2a\u5df2\u6388\u6743\u7684\u65b0\u51a0\u75c5\u6bd2\u68c0\u6d4b\u4ea7\u54c1<\/div>\n
2022\u5e744\u670826\u65e5\uff0cFDA\u66f4\u65b0\u4e86\u622a\u81f3\u5f53\u65e5\u4e3a\u6b62\uff0c\u5df2\u6388\u6743\u65b0\u51a0\u75c5\u6bd2\u68c0\u6d4b\u7684\u6570\u76ee\u4ee5\u53ca\u5206\u7c7b\uff0c\u4ee5\u4e0b\u4e3a\u66f4\u65b0\u5185\u5bb9\uff1a<\/div>\n
FDA \u6839\u636e\u7d27\u6025\u4f7f\u7528\u6388\u6743 (EUA) \u6388\u6743\u4e86 431 \u9879\u68c0\u6d4b\u548c\u6837\u672c\u91c7\u96c6\u8bbe\u5907\u3002\u5176\u4e2d\u5305\u62ec 296 \u9879\u5206\u5b50\u68c0\u6d4b\u548c\u6837\u672c\u91c7\u96c6\u8bbe\u5907\u300184 \u9879\u6297\u4f53\u548c\u5176\u4ed6\u514d\u75ab\u53cd\u5e94\u68c0\u6d4b\u300150 \u9879\u6297\u539f\u68c0\u6d4b\u548c 1 \u9879\u8bca\u65ad\u6027\u547c\u6c14\u68c0\u6d4b\u3002\u53ef\u7528\u4e8e\u5bb6\u5ead\u91c7\u96c6\u7684\u6837\u672c\u4e2d\u670977\u4e2a\u5206\u5b50\u6388\u6743\u548c1\u4e2a\u6297\u4f53\u6388\u6743\u30021\u4e2aEUA\u5728\u5bb6\u68c0\u6d4b\u7684\u5206\u5b50\u5904\u65b9\uff0c2 \u4e2a EUA\u5728\u5bb6\u68c0\u6d4b\u7684\u6297\u539f\u5904\u65b9\uff0c17 \u4e2a EUA\u5728\u5bb6\u68c0\u6d4b\u7684\u6297\u539f\u975e\u5904\u65b9 (OTC) \uff0c3 \u4e2a\u5728\u5bb6\u68c0\u6d4b\u7684\u5206\u5b50 OTC \u00a0\u3002<\/div>\n
FDA \u5df2\u6388\u6743\u7528\u4e8e\u7cfb\u5217\u7b5b\u67e5\u9879\u76ee\u7684 28 \u9879\u6297\u539f\u68c0\u6d4b\u548c 9 \u9879\u5206\u5b50\u68c0\u6d4b\u3002FDA \u8fd8\u6388\u6743\u5bf9EUA\u8fdb\u884c 945 \u6b21\u4fee\u8ba2\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-roundup-april-26-2022<\/div>\n
\u00a0<\/div>\n

\u2756\u00a0\u65b0\u4e00\u4ee3\u5373\u7528\u578bCAR-T\u7597\u6cd5\u83b7FDA\u5b64\u513f\u836f\u8d44\u683c<\/p>\n

\u8fd1\u65e5\uff0cAllogene Therapeutics\u5ba3\u5e03\uff0c\u5728\u7814CAR-T\u7597\u6cd5ALLO-605\u5df2\u83b7\u7f8e\u56fdFDA\u5b64\u513f\u836f\u8d44\u683c\uff0c\u7528\u4e8e\u6cbb\u7597\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u3002ALLO-605\u662f\u8be5\u516c\u53f8\u7684TurboCAR\u6280\u672f\u5e73\u53f0\u5f00\u53d1\u7684\u9996\u6b3e\u5728\u7814\u7597\u6cd5\uff0c\u76ee\u524d\u5904\u4e8e1\u671f\u4e34\u5e8a\u5f00\u53d1\u9636\u6bb5\u3002BCMA\u662f\u591a\u53d1\u6027\u9aa8\u9ad3\u7624\u7ec6\u80de\u4e0a\u666e\u904d\u8868\u8fbe\u7684\u6297\u539f\uff0c\u662f\u5df2\u7ecf\u5f97\u5230\u9a8c\u8bc1\u7684\u6297\u764c\u9776\u70b9\u3002Allogene Therapeutics\u662f\u4e00\u5bb6\u4e34\u5e8a\u9636\u6bb5\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u5f00\u53d1\u9488\u5bf9\u764c\u75c7\u7684\u540c\u79cd\u5f02\u4f53\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\uff08AlloCAR-T\uff09\u4ea7\u54c1\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/ir.allogene.com\/news-releases\/news-release-details\/allogene-therapeutics-receives-fda-orphan-drug-designation-allo<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u91cd\u5e86\u5e02\u4e24\u6c5f\u751f\u547d\u79d1\u6280\u57ce\u4eae\u76f8\uff0c\u7784\u51c6\u5343\u4ebf\u7ea7\u751f\u547d\u5065\u5eb7\u5e02\u573a<\/div>\n
2022\u5e744\u670825\u65e5\uff0c\u91cd\u5e86\u5e02\u4e24\u6c5f\u751f\u547d\u79d1\u6280\u57ce\u6b63\u5f0f\u4eae\u76f8\uff0c\u5c55\u671b\u53d1\u5c55\u5343\u4ebf\u7ea7\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u5e02\u573a\u3002\u4e24\u6c5f\u65b0\u533a\u5c06\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u4f5c\u4e3a\u7b2c\u4e09\u5927\u652f\u67f1\u4ea7\u4e1a\u7684\u91cd\u5927\u90e8\u7f72\uff0c\u5165\u56f4\u91cd\u5e86\u5e02\u53d1\u5c55\u751f\u7269\u533b\u836f\u4ea7\u4e1a\u7684\u91cd\u70b9\u533a\u53bf\u4e4b\u4e00\u30022019\u5e74\u81f32021\u5e74\uff0c\u65b0\u533a\u751f\u7269\u533b\u836f\u4ea7\u4e1a\u4ea7\u503c\u63a5\u8fd1\u767e\u4ebf\uff0c\u662f\u9664\u6c7d\u8f66\u3001\u7535\u5b50\u5916\uff0c\u65b0\u533a\u4e00\u5927\u7a33\u5b9a\u52a0\u901f\u5d1b\u8d77\u7684\u4ea7\u4e1a\u3002\uff08\u70b9\u51fb\u67e5\u770b\u8be6\u60c5\uff09<\/a><\/div>\n
\u00a0<\/div>\n
\u6295\u878d\u8d44<\/div>\n
\u2756\u00a02022\u5e74\u7b2c\u4e00\u5b63\u5ea6\u90e8\u5206\u56fd\u5185\u57fa\u56e0\u4f01\u4e1a\u8425\u6536\u60c5\u51b5<\/div>\n\n
\n
\"RmFicvQBAkgAZqVVa4N8I6xSpYRticmoicicdOMg4HAUbukMjUrL2ibVlEich0bKVExUvGo5GY5mqjqERrdgeIiaicmQ0Q\"\/<\/figure><\/div>\n\n<\/div>\n
<\/div>\n
\u603b\u7ed3\uff1a\u636e\u76ee\u524d\u5df2\u7edf\u8ba1\u7684\u56fd\u5185\u90e8\u5206\u57fa\u56e0\u4f01\u4e1a2022\u5e74\u7b2c\u4e00\u5b63\u5ea6\u8425\u6536\u60c5\u51b5\uff0c\u6309\u7167\u603b\u8425\u6536\u89c4\u6a21\u6392\u5217\uff0c\u5176\u4e2d\u836f\u660e\u5eb7\u5fb7\u4ee584.7\u4ebf\u5143\u6682\u5217\u7b2c\u4e00\uff1b\u5176\u6b21\u4e3a\u8fea\u5b89\u8bca\u65ad\u548c\u91d1\u57df\u533b\u5b66\uff0c\u603b\u8425\u6536\u572840\u4ebf\u5143\u4ee5\u4e0a\u3002\u53e6\u5916\u503c\u5f97\u4e00\u63d0\u7684\u662f\uff0c\u4e07\u5b5a\u751f\u7269\u3001\u660e\u5fb7\u751f\u7269\u4ee5\u53ca\u51ef\u666e\u751f\u7269\u4e09\u5bb6\u516c\u53f8\u57282022\u5e74\u7b2c\u4e00\u5b63\u5ea6\u7684\u8425\u6536\u8f83\u53bb\u5e74\u7ffb\u500d\u589e\u957f\uff0c\u5206\u522b\u4e3a276.87%\u3001267.41%\u548c147.87%\u3002<\/div>\n
<\/div>\n
<\/div>\n<\/p>\n
\u2756\u00a02022\u5e74\u7b2c\u4e00\u5b63\u5ea6\u90e8\u5206\u56fd\u5916\u57fa\u56e0\u4f01\u4e1a\u8425\u6536\u60c5\u51b5<\/div>\n
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\n\n
\n
\"RmFicvQBAkgAZqVVa4N8I6xSpYRticmoicicj2eObTdGX0YHOvY6xEZC220DINCXZmJD7iaZSRsjAUuQwic3al5EvTYA\"\/<\/figure><\/div>\n\n<\/div>\n
<\/div>\n
\u603b\u7ed3\uff1a\u636e\u76ee\u524d\u5df2\u7edf\u8ba1\u7684\u56fd\u5916\u90e8\u5206\u57fa\u56e0\u4f01\u4e1a2022\u5e74\u7b2c\u4e00\u5b63\u5ea6\u8425\u6536\u60c5\u51b5\uff0c\u96c5\u57f9\u4ee5\u53ca\u8d5b\u9ed8\u98de\u8425\u6536\u8d85100\u4ebf\u7f8e\u5143\uff0c\u4f4d\u5217\u524d\u8305\uff1bMDxHealth\u867d\u6392\u540d\u504f\u540e\uff0c\u4f46\u5176\u8425\u6536\u8f83\u53bb\u5e74\u7b2c\u4e00\u5b63\u5ea6\u540c\u6bd4\u589e\u957f\u4e8619.60%\uff1b\u53e6\u5916\u9700\u8981\u63d0\u9192\u7684\u662f\uff0c\u7f57\u6c0f\u8bca\u65ad\u7684171.6\u4ebf\u7f8e\u5143\u4e3a\u9500\u552e\u989d\uff0c\u5e76\u975e\u8425\u4e1a\u6536\u5165\u3002<\/div>\n<\/p>\n
\u2756\u00a02022\u5e744\u6708\u56fd\u5185\u57fa\u56e0\u4f01\u4e1a\u6295\u878d\u8d44\u7edf\u8ba1\u8868<\/div>\n
\n\n
\n
\"RmFicvQBAkgAZqVVa4N8I6xSpYRticmoicicNiapEPJQ5QCwTvsJzmYLM6NIJjQLfeNP6OHtbbTfQKQic5QM37UYGGkA\"\/<\/figure><\/div>\n\n
\u603b\u7ed3\uff1a\u4ece\u76ee\u524d\u7edf\u8ba1\u7684\u878d\u8d44\u89c4\u6a21\u6765\u770b\uff0c2022\u5e744\u6708\u56fd\u5185\u57fa\u56e0\u884c\u4e1a\u53d1\u751f\u878d\u8d44\u4e8b\u4ef69\u8d77\uff0c\u603b\u91d1\u989d\u7ea6\u8fbe8\u4ebf\u5143\u4eba\u6c11\u5e01\uff0c\u5176\u4e2d\u7533\u57fa\u751f\u7269\u4ee5\u878d\u8d443\u4ebf\u5143\u4eba\u6c11\u5e01\u6210\u4e3a4\u6708\u56fd\u5185\u878d\u8d44\u6700\u591a\u7684\u516c\u53f8\uff1b\u4ece\u6295\u8d44\u70ed\u70b9\u6765\u770b\uff0c\u56fd\u5185\u57fa\u56e0\u884c\u4e1a\u878d\u8d44\u70ed\u95e8\u5728\u57fa\u56e0\u8bca\u65ad\u4ee5\u53ca\u57fa\u56e0\u68c0\u6d4b\u9886\u57df\u3002<\/div>\n
\u00a0<\/div>\n
4\u6708\u56fd\u5185\u878d\u8d44\u57fa\u56e0\u4f01\u4e1a\u4ee3\u8868\u7b80\u4ecb\uff1a<\/div>\n
M20 Genomics\u662f\u4e00\u5bb6\u4ece\u4e8b\u5355\u7ec6\u80de\u6d4b\u5e8f\u6280\u672f\u5f00\u53d1\u53ca\u5176\u76f8\u5173\u5e94\u7528\u7684\u751f\u547d\u79d1\u6280\u516c\u53f8\uff0c\u603b\u90e8\u4f4d\u4e8e\u676d\u5dde\u672a\u6765\u79d1\u6280\u57ce\uff0c\u62e5\u6709\u5168\u7403\u9996\u521b\u548c\u9886\u5148\u7684\u65b0\u4e00\u4ee3\u5355\u7ec6\u80de\u6d4b\u5e8f\u6280\u672f\u3002\uff08\u516c\u4f17\u53f7\u8be6\u60c5\uff09<\/a><\/div>\n
\u00a0<\/div>\n
\u827e\u7c73\u68ee\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u5168\u7403\u9ad8\u53d1\u6076\u6027\u80bf\u7624\u65e9\u671f\u65e0\u521b\u68c0\u6d4b\u4ea7\u54c1\u7814\u53d1\u3001\u6ce8\u518c\u3001\u751f\u4ea7\u53ca\u9500\u552e\u7684\u9ad8\u65b0\u6280\u672f\u4f01\u4e1a\u3002\u76ee\u524d\uff0c\u516c\u53f8\u7ed3\u76f4\u80a0\u764c\u68c0\u6d4b\u4ea7\u54c1\u201c\u827e\u957f\u5eb7\u00ae\u201d\u5df2\u83b7NMPA\u6ce8\u518c\u8ba4\u8bc1\uff0c\u662f\u56fd\u5185\u9996\u4e2a\u53cc\u9776\u70b9\u7caa\u4fbfDNA\u7532\u57fa\u5316\u68c0\u6d4b\u7ed3\u76f4\u80a0\u764c\u7684\u4ea7\u54c1\uff0c\u540c\u65f6\u8be5\u4ea7\u54c1\u83b7\u5f97\u5de5\u4fe1\u90e8\u79d1\u5b66\u6280\u672f\u6210\u679c\u767b\u8bb0\u8bc1\u4e66\u5e76\u7ecf\u4f17\u591a\u4e13\u5bb6\u8bc4\u5b9a\u8fbe\u5230\u56fd\u9645\u5148\u8fdb\u6c34\u5e73\u3002\u6b64\u5916\uff0c\u516c\u53f8\u5bab\u9888\u764c\u3001\u5b50\u5bab\u5185\u819c\u764c\u7b49\u591a\u6b3e\u764c\u75c7\u65e9\u671f\u68c0\u4ea7\u54c1\u5747\u5df2\u901a\u8fc7CE\u8ba4\u8bc1\u3002<\/div>\n
\u5b98\u7f51>>https:\/\/www.ammulifetech.com\/<\/div>\n
\u00a0<\/div>\n
\u660e\u667a\u533b\u7597\u662f\u56fd\u5185\u9886\u5148\u7684\u80bf\u7624\u5927\u6570\u636e\u670d\u52a1\u4f01\u4e1a\uff0c\u5176\u80bf\u7624\u771f\u5b9e\u4e16\u754c\u5927\u6570\u636e\u5e73\u53f0\u4e3a\u836f\u68b0\u4f01\u4e1a\u63d0\u4f9b\u57fa\u4e8e\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u6846\u67b6\u7684\u4e34\u5e8a\u7814\u7a76\u670d\u52a1\uff0c\u540c\u65f6\u4e3a\u533b\u7597\u673a\u6784\u548c\u60a3\u8005\u63d0\u4f9b\u57fa\u4e8e\u4e2d\u56fd\u80bf\u7624\u60a3\u8005\u8bca\u7597\u6570\u636e\u4f53\u7cfb\u548c\u8bca\u7597\u65b9\u6848\u6240\u6253\u9020\u7684\u80bf\u7624AI\u6570\u5b57\u7597\u6cd5\u7cfb\u5217\u4ea7\u54c1\u3002<\/div>\n
\u5b98\u7f51>>http:\/\/www.wiseltd.cn\/<\/div>\n
\u00a0<\/div>\n
\u4e07\u8d35\u6e90\u662f\u4e00\u5bb6\u4e3aIVD\u3001\u533b\u7597\u5668\u68b0\u3001\u751f\u547d\u79d1\u5b66\u3001\u751f\u7269\u533b\u836f\u4f01\u4e1a\u63d0\u4f9b\u6838\u5fc3\u5de5\u827a\u3001\u88c5\u5907\u3001\u89e3\u51b3\u65b9\u6848\u7684\u4e00\u7ad9\u5f0f\u670d\u52a1\u7684\u6574\u4f53\u5de5\u7a0b\u65b9\u6848\u89e3\u51b3\u5546\u3002<\/div>\n
\u5b98\u7f51>>http:\/\/www.welgwiyan.com\/index.html<\/div>\n
\u00a0<\/div>\n
\u2756\u00a02022\u5e744\u6708\u56fd\u5916\u57fa\u56e0\u4f01\u4e1a\u6295\u878d\u8d44\u7edf\u8ba1\u8868<\/div>\n\n
\n
\"RmFicvQBAkgAZqVVa4N8I6xSpYRticmoicicsx0fsRzes1oM6TXBsGLzldFR1U6CkYvhDibAQuYxh0J9K3ELE9tbCqQ\"\/<\/figure><\/div>\n\n
\u603b\u7ed3\uff1a\u4ece\u76ee\u524d\u7edf\u8ba1\u7684\u878d\u8d44\u89c4\u6a21\u6765\u770b\uff0c2022\u5e744\u6708\u56fd\u5916\u57fa\u56e0\u884c\u4e1a\u53d1\u751f\u878d\u8d44\u4e8b\u4ef66\u8d77\uff0c\u603b\u91d1\u989d\u8fbe6.06\u4ebf\u7f8e\u5143\uff08\u7ea640\u4ebf\u5143\u4eba\u6c11\u5e01\uff09\uff0c\u5176\u4e2dTessera Therapeutics \u4ee5\u878d\u8d44\u8d853\u4ebf\u7f8e\u5143\u6210\u4e3a4\u6708\u56fd\u5916\u878d\u8d44\u6700\u591a\u7684\u516c\u53f8\uff1b\u4ece\u6295\u8d44\u70ed\u70b9\u6765\u770b\uff0c\u56fd\u5916\u57fa\u56e0\u884c\u4e1a\u878d\u8d44\u5206\u5e03\u5728\u57fa\u56e0\u6cbb\u7597\u3001\u57fa\u56e0\u8bca\u65ad\u4ee5\u53ca\u57fa\u56e0\u6280\u672f\u57fa\u7840\u8bbe\u65bd\u9886\u57df\u3002<\/div>\n
\u00a0<\/div>\n
4\u6708\u56fd\u5916\u878d\u8d44\u57fa\u56e0\u4f01\u4e1a\u4ee3\u8868\u7b80\u4ecb\uff1a<\/div>\n
Tessera\u00a0Therapeutics\u00a0\u662f\u4e00\u5bb6\u6210\u7acb\u00a04 \u5e74\u7684\u57fa\u56e0\u6cbb\u7597\u65b0\u9510\u516c\u53f8\uff0c\u7531\u7f8e\u56fd\u751f\u547d\u79d1\u5b66\u98ce\u6295\u673a\u6784 Flagship Pioneering\uff08FP\uff09\u5b75\u5316\u6210\u7acb\uff0c\u53d7\u5230\u79fb\u52a8\u9057\u4f20\u5143\u4ef6 (MGE) \u542f\u53d1\uff0c\u4e13\u6ce8\u4e8e\u5f00\u53d1\u57fa\u56e0\u5199\u5165\uff08Gene Writing\uff09\u6cbb\u7597\u65b9\u6cd5\uff0c\u91cd\u70b9\u9002\u5e94\u75c7\u662f\u809d\u810f\u548c\u7f55\u89c1\u75be\u75c5\u3002<\/div>\n
\u5b98\u7f51>>https:\/\/www.tesseratherapeutics.com\/<\/div>\n
\u00a0<\/div>\n
Genome Insight \u662f\u97e9\u56fd\u79d1\u5b66\u6280\u672f\u9ad8\u7b49\u7814\u7a76\u9662 (KAIST) \u7684\u884d\u751f\u516c\u53f8\uff0c\u65e8\u5728\u52a0\u901f\u533b\u7597\u4fdd\u5065\u9886\u57df\u7684\u57fa\u56e0\u7ec4\u9769\u547d\u3002<\/div>\n
\u5b98\u7f51>>http:\/\/www.genomeinsight.net\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u7ef4\u68a7\u8d44\u672c\u5408\u8d44\u6210\u7acb\u6cbb\u7597\u5fc3\u810f\u4ee3\u8c22\u75c5\u7684RNAi\u7597\u6cd5\u516c\u53f8<\/div>\n
2022\u5e744\u670825\u65e5\uff0c\u7ef4\u68a7\u8d44\u672c\u4e0eArrowhead Pharmaceuticals\u6210\u7acb\u4e00\u5bb6\u5408\u8d44\u516c\u53f8Visirna Therapeutics\u3002\u8be5\u5408\u8d44\u516c\u53f8\u5c06\u83b7\u5f97\u5728\u6211\u56fd\u5185\u5730\u53ca\u6e2f\u6fb3\u53f0\u5730\u533a\u5f00\u53d1\u548c\u5546\u4e1a\u5316Arrowhead\u516c\u53f8\u7684\u56db\u79cd\u57fa\u4e8eRNAi\u7597\u6cd5\u6cbb\u7597\u5fc3\u810f\u4ee3\u8c22\u75be\u75c5\u7684\u5728\u7814\u836f\u7269\u7684\u72ec\u5bb6\u6743\u5229\u3002<\/div>\n
\u00a0<\/div>\n
\u4f1a\u8bae\u63a8\u8350<\/div>\n
\u2756\u00a02022\u5e74\u4e9a\u6d32\u52a8\u690d\u7269\u57fa\u56e0\u7ec4\u5927\u4f1a\uff0c6\u670822\u65e5-24\u65e5\uff0c\u7ebf\u4e0a\u4f1a\u8bae<\/div>\n
PAG ASIA 2022\uff082022\u5e74\u4e9a\u6d32\u52a8\u690d\u7269\u57fa\u56e0\u7ec4\u5927\u4f1a\uff09\u5c06\u4e8e2022\u5e746\u670822\u65e5\u81f324\u65e59:00 AM – 05:30 PM\u5728\u7ebf\u4e0a\u4e3e\u529e\u3002\u4f1a\u8bae\u76ee\u7684\u662f\u4e3a\u5e94\u5bf9\u4e0d\u65ad\u6269\u5927\u7684\u5168\u7403\u4eba\u53e3\u3001\u5168\u7403\u6c14\u5019\u53d8\u5316\u4ee5\u53ca\u4e9a\u592a\u5730\u533a\u53d1\u751f\u7684\u5f15\u4eba\u6ce8\u76ee\u7684\u52a8\u690d\u7269\u57fa\u56e0\u7ec4\u7814\u7a76\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.intlpagasia.org\/2022<\/div>\n
\u00a0<\/div>\n
\u2756\u00a02022\u5e74\u7b2c55\u5c4a\u6b27\u6d32\u4eba\u7c7b\u9057\u4f20\u5b66\u5b66\u4f1a\u5e74\u4f1a\uff0c6\u670811\u65e5-14\u65e5\uff0c\u7ef4\u4e5f\u7eb3<\/div>\n
2022\u5e74\u7b2c55\u5c4a\u6b27\u6d32\u4eba\u7c7b\u9057\u4f20\u5b66\u5b66\u4f1a\u5e74\u4f1a\uff08ESHG\uff09\u5c06\u4e8e2022\u5e746\u670811\u65e5\u81f314\u65e5\u5728\u5965\u5730\u5229\u7ef4\u4e5f\u7eb3\u4e3e\u884c\u3002\u4f1a\u8bae\u4e3b\u529e\u65b9\u662f\u6b27\u6d32\u4eba\u7c7b\u9057\u4f20\u5b66\u4f1a\uff0c\u4e3e\u529e\u4f1a\u8bae\u7684\u76ee\u7684\u662f\u4e3a\u4e86\u4f20\u64ad\u4eba\u7c7b\u9057\u4f20\u5b66\u9886\u57df\u7684\u6700\u65b0\u8fdb\u5c55\u4ee5\u53ca\u4e3a\u5b66\u79d1\u5916\u4e0d\u540c\u9886\u57df\u53d6\u5f97\u7684\u8fdb\u5c55\u63d0\u4f9b\u770b\u6cd5\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.globalconfs.com\/meeting\/2187.html<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u53d1\u5c55<\/div>\n

\u2756\u00a0Illumina\u4e0e\u798f\u541b\u57fa\u56e0\u5408\u4f5c\u5f00\u53d1\u5168\u6808\u5f0f\u9057\u4f20\u75c5\u5206\u6790\u89e3\u51b3\u65b9\u6848\u00a0<\/p>\n

2022\u5e744\u670830\u65e5\uff0c\u00a0Illumina\u4e0e\u798f\u541b\u57fa\u56e0\u7ebf\u4e0a\u53d1\u5e03\u201cDRAGEN x ISoGenetic \u5168\u6808\u5f0f\u9057\u4f20\u75c5\u5206\u6790\u89e3\u51b3\u65b9\u6848\u201d\u3002\u8be5\u4ea7\u54c1\u662f\u4e3a\u4e34\u5e8a\u53ca\u79d1\u7814\u5de5\u4f5c\u8005\u6253\u9020\u7684\u6570\u636e\u5206\u6790\u53ca\u89e3\u8bfb\u5de5\u5177\uff0c\u81f4\u529b\u4e8e\u63d0\u9ad8\u9057\u4f20\u75c5\u60a3\u8005\u7684\u4e34\u5e8a\u8bca\u65ad\u7387\u3002\uff08\u70b9\u51fb\u67e5\u770b\u8be6\u60c5\uff09<\/a><\/p>\n

 <\/p>\n

\u2756\u00a0Illumina\u4e0eJanssen\u00a0Biotech\u5408\u4f5c\u5f00\u53d1\u7cbe\u51c6\u836f\u7269\u00a0<\/p>\n

2022\u5e744\u670827\u65e5\uff0cIllumina\u5728\u4f26\u6566\u4e3e\u884c\u7684\u4e16\u754c\u4f34\u968f\u8bca\u65ad\u5cf0\u4f1a\u4e0a\u5ba3\u5e03\u4e0eJanssen Biotech\u5efa\u7acb\u957f\u671f\u6218\u7565\u5408\u4f5c\uff0c\u4ee5\u52a0\u901f\u7cbe\u51c6\u836f\u7269\u5f00\u53d1\u3002\u6b64\u6b21\u5408\u4f5c\u65e8\u5728\u5229\u7528Illumina\u5305\u62ec\u57fa\u4e8e AI \u7684\u57fa\u56e0\u7ec4\u89e3\u91ca\u5de5\u5177\u3001\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u548c\u591a\u7ec4\u5206\u6790\u670d\u52a1\u5728\u5185\u7684\u8d44\u6e90\u7ec4\u5408\uff0c\u4e24\u4e2a\u516c\u53f8\u5c06\u5171\u540c\u5f00\u53d1Illumina\u7684 TruSight \u80bf\u7624\u5b66\u7efc\u5408\u5206\u6790\u7684\u4f34\u968f\u8bca\u65ad\u9879\u76ee\u3002<\/div>\n
\u00a0<\/div>\n

\u2756\u00a0Evaxion Biotech\u4e0ePersonalis\u5408\u4f5c\u8fdb\u884c\u9ed1\u8272\u7d20\u7624\u514d\u75ab\u6cbb\u7597\u8bd5\u9a8c\u00a0<\/p>\n

2022\u5e744\u670826\u65e5\uff0c\u4e2a\u6027\u5316\u764c\u75c7\u6cbb\u7597\u516c\u53f8Evaxion Biotech\u548c\u764c\u75c7\u57fa\u56e0\u7ec4\u5b66\u516c\u53f8Personalis \u5ba3\u5e03\u5c06\u5728IIb\u671f\u8bd5\u9a8c\u4e2d\u4f7f\u7528Personalis\u7684\u514d\u75ab\u5206\u6790\u5e73\u53f0\uff0c\u8bc4\u4f30Evaxion\u7684\u65b0\u8868\u4f4d\u9776\u5411\u6cbb\u7597 EVX-01\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\uff0c\u5e76\u7ed3\u5408\u9ed8\u514b\u516c\u53f8\u7684Keytruda\uff08pembrolizumab\uff09\uff0c\u7528\u4e8e\u665a\u671f\u9ed1\u8272\u7d20\u7624\u60a3\u8005\u3002EVX-01\u662f\u4e00\u79cd\u57fa\u4e8eEvaxion\u4e13\u6709\u7684\u4eba\u5de5\u667a\u80fd\u9a71\u52a8\u7684PIONEER\u6280\u672f\u5e73\u53f0\uff0c\u5f00\u53d1\u7684\u521b\u65b0\u4e2a\u4f53\u5316\u764c\u75c7\u514d\u75ab\u7597\u6cd5\u3002<\/div>\n
\u00a0<\/div>\n

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\u8fd1\u65e5\uff0c\u7531GE\u533b\u7597\u3001\u7f57\u6c0f\u8bca\u65ad\u3001\u535a\u9ccc\u4e00\u9f84\u533b\u7597\u96c6\u56e2\u4e0e\u5b87\u901a\u6c7d\u8f66\u5171\u540c\u6253\u9020\u7684\u5168\u56fd\u9996\u4e2a\u201c5G\u6570\u5b57\u79fb\u52a8\u533b\u9662\u201d\u6b63\u5f0f\u4ea4\u4ed8\uff0c\u56db\u8f86\u79fb\u52a8\u533b\u7597\u8f66\u5df2\u7ecf\u5f00\u5230\u4e86\u6d77\u5357\u535a\u9ccc\u4e00\u9f84\u751f\u547d\u517b\u62a4\u4e2d\u5fc3\u3002\u9879\u76ee\u76ee\u524d\u4ea4\u4ed8\u7684\u5185\u5bb9\u5206\u522b\u4e3a\u56db\u8f86\u8f66\u7684\u4f53\u68c0\u4e2d\u5fc3\u3001\u533b\u5b66\u68c0\u9a8c\u3001CT\u5f71\u50cf\u68c0\u67e5\u3001\u5973\u6027\u4e24\u764c\u7b5b\u67e5\u56db\u4e2a\u529f\u80fd\u6a21\u5757\uff0c\u5f00\u521b\u4e86\u56fd\u5185\u4ee5\u521b\u65b0\u533b\u7597\u8bbe\u5907\u548c\u8fdc\u7a0b\u6570\u5b57\u533b\u7597\u6280\u672f\u4e3a\u57fa\u7840\u7684\u79fb\u52a8\u533b\u7597\u670d\u52a1\u65b0\u6a21\u5f0f\u3002<\/div>\n
\u00a0<\/div>\n
\u79d1\u7814\u53d1\u73b0<\/div>\n

\u2756\u00a0\u6c64\u5bcc\u916c\u56e2\u961f\u5229\u7528\u5355\u7ec6\u80de\u5206\u6790\u8bc4\u4ef7\u4f53\u5916\u7ed3\u76f4\u80a0\u764c\u7c7b\u5668\u5b98\u57f9\u517b\u4f53\u7cfb<\/p>\n

2022\u5e744\u670828\u65e5\uff0c\u5317\u4eac\u5927\u5b66\u751f\u7269\u533b\u5b66\u524d\u6cbf\u521b\u65b0\u4e2d\u5fc3\u6c64\u5bcc\u916c\u56e2\u961f\u4e0e\u5317\u4eac\u5927\u5b66\u7b2c\u4e09\u533b\u9662\u666e\u5916\u79d1\u4ed8\u536b\u56e2\u961f\u5728\u00a0Genome Biology\u00a0\u520a\u6587\uff0c\u5bf9\u6765\u81ea7\u540d\u7ed3\u76f4\u80a0\u764c\u60a3\u8005\u7684\u4f53\u5185\u80bf\u7624\u7ec4\u7ec7\u548c\u764c\u65c1\u6b63\u5e38\u7ec4\u7ec7\uff0c\u4ee5\u53ca\u5bf9\u5b83\u4eec\u8fdb\u884c\u4f53\u5916\u57f9\u517b\u5efa\u7acb\u76f8\u5e94\u7684\u7c7b\u5668\u5b98\u8fdb\u884c\u9ad8\u7cbe\u5ea6\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u5e76\u7cfb\u7edf\u8bc4\u4f30\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/genomebiology.biomedcentral.com\/articles\/10.1186\/s13059-022-02673-3<\/div>\n
\u00a0<\/div>\n

\u2756\u00a0\u7814\u7a76\u53d1\u73b0TLR7\u529f\u80fd\u83b7\u5f97\u6027\u57fa\u56e0\u53d8\u5f02\u8bf1\u53d1\u4eba\u7c7b\u72fc\u75ae\u4ea7\u751f<\/p>\n

2022\u5e744\u670827\u65e5\uff0c\u6fb3\u5927\u5229\u4e9a\u56fd\u7acb\u5927\u5b66Carola G. Vinuesa\u7814\u7a76\u7ec4\u5728Nature\u520a\u6587\uff0c\u5ba3\u5e03\u53d1\u73b0Toll-like receptor 7 \uff08TLR7\uff09\u529f\u80fd\u83b7\u5f97\u53d8\u4f53\u662f\u9020\u6210\u4eba\u7c7b\u7cfb\u7edf\u6027\u7ea2\u6591\u72fc\u75ae\u7684\u4e00\u4e2a\u539f\u56e0\u3002\u7814\u7a76\u786e\u5b9a\u4e86TLR7\u548c\u542b\u9e1f\u82f7\u81ea\u8eab\u914d\u4f53\u5bf9\u4eba\u7c7b\u72fc\u75ae\u53d1\u75c5\u7684\u91cd\u8981\u6027\uff0c\u8fd9\u4e3a\u6cbb\u7597\u6027TLR7\u5e94\u7528\u6216\u6291\u5236MyD88\u94fa\u5e73\u4e86\u9053\u8def\u3002\u636e\u6089\uff0c\u7814\u7a76\u56e2\u961f\u76ee\u524d\u6b63\u4e0e\u5236\u836f\u516c\u53f8\u5408\u4f5c\u5f00\u53d1\u6216\u91cd\u65b0\u5229\u7528\u73b0\u6709\u7684\u9776\u5411TLR7\u57fa\u56e0\u7597\u6cd5\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41586-022-04642-z<\/div>\n
\u00a0<\/div>\n

\u2756\u00a0\u57fa\u56e0\u7ec4\u7814\u7a76\u63ed\u793a\u6211\u56fd\u85cf\u5f5d\u8d70\u5eca\u5c45\u6c11\u7684\u590d\u6742\u8d77\u6e90<\/p>\n

2022\u5e744\u670826\u65e5\uff0c\u674e\u751f\u658c\u7b49\u79d1\u5b66\u5bb6\u5728Cell Reports\u520a\u6587\uff0c\u63ed\u793a\u4e86\u6211\u56fd\u85cf\u5f5d\u8d70\u5eca\u5c45\u6c11\u7684\u590d\u6742\u8d77\u6e90\u3002\u7531\u4e8e\u8be5\u5730\u9661\u5ced\uff0c\u6570\u636e\u96be\u4ee5\u6536\u96c6\uff0c\u8bba\u6587\u7684\u5171\u540c\u901a\u8baf\u4f5c\u8005\u3001\u4e2d\u56fd\u897f\u5b89\u4ea4\u901a\u5927\u5b66\u7684\u674e\u751f\u658c\u56e2\u961f\u82b1\u4e8610\u5e74\u65f6\u95f4\uff0c\u4ece\u8be5\u5730\u533a\u6240\u670916\u4e2a\u6c11\u65cf\u7684200\u591a\u4eba\u4e2d\u91c7\u96c6\u4e86\u8840\u6db2\u6837\u672c\u3002\u7814\u7a76\u53d1\u73b0\uff0c\u8be5\u5730\u533a\u6240\u6709\u6c11\u65cf\u7684\u57fa\u56e0\u90fd\u5f88\u76f8\u4f3c\uff0c\u4f46\u751f\u6d3b\u5728\u85cf\u5f5d\u8d70\u5eca\u5317\u90e8\u5730\u533a\u7684\u4eba\u4e0e\u751f\u6d3b\u5728\u9ad8\u539f\u4e0a\u7684\u9752\u85cf\u9ad8\u539f\u4eba\u7684\u4eb2\u7f18\u5173\u7cfb\u66f4\u5bc6\u5207\uff0c\u800c\u85cf\u5f5d\u8d70\u5eca\u5357\u90e8\u5730\u533a\u7684\u4eba\u4e0e\u4e1c\u5357\u4e9a\u4eba\u5982\u6cf0\u56fd\u4eba\u3001\u67ec\u57d4\u5be8\u4eba\u7684\u4eb2\u7f18\u5173\u7cfb\u66f4\u5bc6\u5207\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cell.com\/cell-reports\/fulltext\/S2211-1247(22)00481-8<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u534e\u5927\u6c88\u73a5\u56e2\u961f\u53d1\u5e03\u65b0\u578bDNA\u5b58\u50a8\u7f16\u7801\u7cfb\u7edf<\/div>\n
2022\u5e744\u670825\u65e5\uff0c\u534e\u5927\u7814\u7a76\u6240\u3001\u6df1\u5733\u56fd\u5bb6\u57fa\u56e0\u5e93\u7b49\u7814\u7a76\u56e2\u961f\u5728Nature Computational Science\u520a\u6587\u53d1\u8868\u4e86\u4ee5\u201cBT+IT\u201d\u878d\u5408\u7684DNA\u4fe1\u606f\u5b58\u50a8\u6280\u672f\u7684\u7814\u7a76\u6210\u679c\u3002\u56e2\u961f\u5f00\u521b\u4e86\u540d\u4e3a\u201c\u9634\u9633\u201d\u7684\u6bd4\u7279-\u78b1\u57fa\u7f16\u89e3\u7801\u7cfb\u7edf\uff0c\u7528\u4ee5\u89e3\u51b3\u5f53\u524dDNA\u4fe1\u606f\u5b58\u50a8\u9886\u57df\u7684\u6280\u672f\u96be\u9898\u3002\u8fd1\u65e5\uff0c\u57fa\u56e0\u6167\u8054\u5408\u534e\u5927\u7814\u7a76\u9662\u3001\u56fd\u5bb6\u57fa\u56e0\u5e93\u3001\u534e\u5927\u667a\u9020\u3001\u8054\u5ddd\u751f\u7269\u3001\u751f\u5de5\u751f\u7269\u3001\u64ce\u79d1\u751f\u7269\u7b49\u673a\u6784\u5c06\u53d1\u5e03\u9996\u90e8\u4e2d\u6587\u7248\u300aDNA\u5b58\u50a8\u84dd\u76ae\u4e66\u300b\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s43588-022-00231-2<\/div>\n
\u7f16\u8f91 | \u5f20\u742a<\/div>\n
\u5ba1\u6838 | \u5e03\u4e09\u5c11<\/div>\n\n
\n
\"RmFicvQBAkgAZqVVa4N8I6xSpYRticmoicicVPTsVzuhCYToxWgVrdzIIiaVHQMY7V0lTQPVta9eGU0TwezzhMiaHTTw\"\/<\/figure><\/div>\n\n
\u6269\u5c55\u9605\u8bfb<\/div>\n
\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5(186\u671f)\u00a0<\/a>DNA\u5b58\u50a8 | BT\u4e0eIT\u878d\u5408\u7684\u9ed1\u79d1\u6280\u4e0e\u672a\u6765\u4ea7\u4e1a<\/a>\u4e92\u8054\u7f51\u5de8\u5934\u8fdb\u573a\u751f\u547d\u79d1\u6280\u9886\u57df\u7684\u903b\u8f91<\/a><\/div>\n
\u3010\u58f0\u660e\u3011\u4e3a\u4e86\u63a8\u52a8\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u79d1\u6280\u63a8\u5e7f\u3001\u4ea7\u4e1a\u53d1\u5c55\u53ca\u653f\u4ea7\u5b66\u7814\u7528\u8fde\u63a5\uff0c\u57fa\u56e0\u6167\u79c9\u6301\u4e13\u4e1a\u3001\u8d4b\u80fd\u3001\u4e2d\u7acb\u7684\u7acb\u573a\u6536\u96c6\u3001\u5206\u6790\u53ca\u53d1\u5e03\u76f8\u5173\u4fe1\u606f\u3002\u4f46\u7531\u4e8e\u65f6\u6548\u6027\u53ca\u884c\u4e1a\u7279\u6b8a\u6027\uff0c\u6240\u520a\u767b\u5185\u5bb9\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u672a\u7ecf\u8bf4\u660e\u4e0d\u4f5c\u4e3a\u51b3\u7b56\u4f9d\u636e\uff1b\u672c\u6587\u76f8\u5173\u4fe1\u606f\u4e0d\u4ee3\u8868\u57fa\u56e0\u6167\u7684\u89c2\u70b9\uff1b\u57fa\u56e0\u6167\u5e73\u53f0\u520a\u767b\u7684\u539f\u521b\u5185\u5bb9\u7684\u77e5\u8bc6\u4ea7\u6743\u4e3a\u201c\u57fa\u56e0\u6167\u201d\u5546\u6807\u62e5\u6709\u8005\u53ca\u76f8\u5173\u6743\u5229\u4eba\u6240\u6709\uff1b\u6b22\u8fce\u8f6c\u8f7d\uff0c\u8f6c\u8f7d\u8bf7\u7533\u8bf7\u5e76\u6ce8\u660e\u6765\u6e90\u3002\u6b22\u8fce\u4e2a\u4eba\u53ca\u673a\u6784\u6295\u7a3f\u53ca\u5408\u4f5c\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u5173\u4e8e\u57fa\u56e0\u6167\u00a0<\/div>\n
\u57fa\u56e0\u6167\u4e13\u6ce8\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u77e5\u8bc6\u670d\u52a1\u3002\u521b\u59cb\u56e2\u961f\u6df1\u8015\u884c\u4e1a\u4e00\u7ebf\u5341\u4f59\u5e74\uff0c\u79c9\u6301\u201c\u4f7f\u8fde\u63a5\u4ea7\u751f\u4ef7\u503c\uff0c\u7528\u6570\u636e\u770b\u89c1\u672a\u6765\u201d\u7684\u7406\u5ff5\uff0c\u57fa\u4e8e\u4ea7\u4e1a\u667a\u5e93\u548c\u4e13\u4e1a\u5185\u5bb9\uff0c\u63d0\u4f9b\u4ea7\u4e1a\u89c4\u5212\u3001\u884c\u7814\u54a8\u8be2\u3001\u79d1\u6280\u63a8\u5e7f\u7b49\u670d\u52a1\u3002\u8fde\u7eed\u4e94\u5e74\u53d1\u5e03\u884c\u4e1a\u84dd\u76ae\u4e66\uff0c\u88ab\u56fd\u5bb6\u53ca\u7701\u5e02\u7ea7\u4ea7\u4e1a\u62a5\u544a\u6536\u5f55\uff0c\u7ec4\u7ec7\u591a\u5bb6\u5355\u4f4d\u53d1\u5e03\u884c\u4e1a\u5171\u8bc6\u548c\u56e2\u6807\uff0c\u63a8\u52a8\u751f\u547d\u79d1\u6280\u666e\u60e0\u548c\u4ea7\u4e1a\u878d\u5408\u53d1\u5c55\u3002<\/div>\n
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