{"id":8734,"date":"2022-05-09T08:00:00","date_gmt":"2022-05-09T00:00:00","guid":{"rendered":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/05\/09\/485152\/"},"modified":"2026-04-01T11:47:33","modified_gmt":"2026-04-01T03:47:33","slug":"485152","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/05\/09\/485152\/","title":{"rendered":"\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5 | \u57fa\u56e0\u7f16\u8f91\u6216\u53ef\u6210\u5e74\u4eba\u7126\u8651\uff1bGuardant\u53d1\u5e03\u654f\u611f\u5ea691%\u7684\u764c\u75c7\u65e9\u7b5b\u4ea7\u54c1"},"content":{"rendered":"

<\/p>\n

\u805a\u7126<\/div>\n
\u4e00\u5468\u70ed\u70b9<\/div>\n
1 \u963f\u65af\u5229\u5eb7\u3001Illumina\u7b49\u4f01\u4e1a\u673a\u6784\u5c06\u542f\u52a8\u65b0\u751f\u513f\u5feb\u901f\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u8054\u76df<\/div>\n
2 Guardant\u53d1\u5e03\u654f\u611f\u5ea6\u8fbe91%\u7684\u764c\u75c7\u65e9\u7b5b\u4ea7\u54c1<\/div>\n
3 \u57fa\u56e0\u7f16\u8f91\u6216\u53ef\u6cbb\u7597\u6210\u5e74\u4eba\u7126\u8651<\/div>\n
4 \u53d1\u5c55\u751f\u7269\u519c\u4e1a\u3001\u652f\u6301LDT\u8bd5\u70b9\uff0c\u5e7f\u5dde\u53d1\u5e03\u65b0\u5174\u4ea7\u4e1a\u201c\u5341\u56db\u4e94\u201d\u89c4\u5212<\/div>\n
5 \u82f1\u7f8e\u6700\u65b0\u62a5\u544a\u5206\u6790\u591a\u56fd\u51fa\u73b0\u4e0d\u660e\u75c5\u56e0\u513f\u7ae5\u809d\u708e\u6216\u6765\u81ea\u817a\u75c5\u6bd2<\/div>\n
6 10\u5bb6\u4e0a\u5e02\u57fa\u56e0\u4f01\u4e1aQ1\u8425\u6536\u603b\u8ba1\u8fd1155\u4ebf\u5143\u4eba\u6c11\u5e01<\/div>\n
\u2026\u2026\uff08\u66f4\u591a\u8be6\u60c5\u89c1\u57fa\u56e0\u6167\u6bcf\u5468GeneMail\uff09<\/div>\n
\u5934\u6761\u8d44\u8baf<\/div>\n
\u00a0<\/div>\n
\u2756\u963f\u65af\u5229\u5eb7\u3001Illumina\u7b49\u4f01\u4e1a\u673a\u6784\u5c06\u542f\u52a8\u65b0\u751f\u513f\u5feb\u901f\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u8054\u76df<\/div>\n
2022\u5e745\u67086\u65e5\uff0cRady\u513f\u7ae5\u57fa\u56e0\u7ec4\u533b\u5b66\u7814\u7a76\u6240\u603b\u88c1\u517c\u9996\u5e2d\u6267\u884c\u5b98\u65af\u8482\u82ac\u91d1\u65af\u83ab\u5c14\u5728Bio-IT \u4e16\u754c\u5927\u4f1a\u66a8\u535a\u89c8\u4f1a\u4e0a\u5ba3\u5e03\u5c06\u4e0eIllumina\u3001\u963f\u65af\u5229\u5eb7\u7b49\u516c\u53f8\u7ec4\u6210\u5c1a\u672a\u547d\u540d\u7684\u8d22\u56e2\uff0c\u6682\u5b9a\u540d\u4e3aBabySave\u3002\u5f53\u524d\u9636\u6bb5\u5c06\u5bfb\u627e\u5927\u7ea6350\u79cd\u75be\u75c5\u7684\u9057\u4f20\u751f\u7269\u6807\u5fd7\u7269\uff0c\u5e0c\u671b\u57282026\u5e74\u5c06\u8be5\u9879\u76ee\u5546\u4e1a\u5316\u3002\u8054\u76df\u7684\u66f4\u591a\u7ec6\u8282\u4ecd\u9700\u6572\u5b9a\uff0c\u4e0b\u4e2a\u6708\u5c06\u53d1\u5e03\u66f4\u6b63\u5f0f\u7684\u516c\u544a\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.genomeweb.com\/sequencing\/rady-childrens-launch-consortium-rapid-whole-genome-sequencing-newborns#.YndKRf5BzHo<\/div>\n
\u00a0<\/div>\n
\u2756\u53d1\u5c55\u751f\u7269\u519c\u4e1a\u3001\u652f\u6301LDT\u8bd5\u70b9\uff0c\u5e7f\u5dde\u53d1\u5e03\u6218\u7565\u65b0\u5174\u4ea7\u4e1a\u201c\u5341\u56db\u4e94\u201d\u89c4\u5212<\/div>\n
2022\u5e745\u67085\u65e5\uff0c\u5e7f\u5dde\u5e02\u4eba\u6c11\u653f\u5e9c\u516c\u62a5\u53d1\u5e03\u300a\u5e7f\u5dde\u5e02\u4eba\u6c11\u653f\u5e9c\u529e\u516c\u5385\u5173\u4e8e\u5370\u53d1\u5e7f\u5dde\u5e02\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u201c\u5341\u56db\u4e94\u201d\u89c4\u5212\u7684\u901a\u77e5\u300b\uff0c\u6587\u4e2d\u5f3a\u8c03\u52a0\u901f\u53d1\u5c55\u5305\u542b\u5206\u5b50\u80b2\u79cd\u5728\u5185\u7684\u751f\u7269\u519c\u4e1a\u4ea7\u4e1a\u4ee5\u53ca\u7784\u51c6\u7cbe\u51c6\u533b\u7597\u3001\u667a\u6167\u533b\u7597\u7684\u57f9\u517b\u53d1\u5c55\u6027\u5065\u5eb7\u4ea7\u4e1a\u3002\u4ee5\u4e0b\u4e3a\u6574\u7406\u7684\u91cd\u70b9\u5185\u5bb9\uff1a<\/div>\n
\u52a0\u5feb\u751f\u7269\u519c\u4e1a\u7684\u4ea7\u4e1a\u5316\u53d1\u5c55\uff1a<\/div>\n
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\u57f9\u80b2\u53d1\u5c55\u65b0\u578b\u5065\u5eb7\u670d\u52a1\u4e1a\uff1a<\/div>\n
\u7784\u51c6\u7cbe\u51c6\u533b\u7597\u3001\u667a\u6167\u533b\u7597\u9700\u6c42\uff0c\u4f9d\u6258\u57fa\u56e0\u68c0\u6d4b\u548c\u4e2a\u4f53\u5316\u6cbb\u7597\u6280\u672f\u8fdb\u6b65\uff0c\u6784\u5efa\u7cbe\u51c6\u8bca\u7597\u5e73\u53f0\u548c\u4e34\u5e8a\u8f6c\u5316\u4f53\u7cfb\uff0c\u5efa\u8bbe\u56fd\u9645\u9886\u5148\u7684\u7cbe\u51c6\u533b\u7597\u4e2d\u5fc3\u3002<\/div>\n
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\u57fa\u56e0\u68c0\u6d4b\uff1a\u52a0\u5feb\u7a81\u7834\u57fa\u56e0\u6d4b\u5e8f\u4eea\u6838\u5fc3\u90e8\u4ef6\u53ca\u6280\u672f\u5e94\u7528\u74f6\u9888\uff0c\u5f00\u53d1\u5177\u6709\u72ec\u7acb\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\uff0c\u9ad8\u6027\u80fd\u3001\u4f4e\u6210\u672c\u7684\u65b0\u4e00\u4ee3\u57fa\u56e0\u6d4b\u5e8f\u4eea\uff0c\u7814\u53d1\u9ad8\u51c6\u786e\u5ea6\u3001\u591a\u4f4d\u70b9\u7684\u5206\u5b50\u8bca\u65ad\u8bbe\u5907\u548c\u914d\u5957\u8bd5\u5242\uff0c\u4ee5\u53ca\u9ad8\u5bc6\u5ea6\u57fa\u56e0\u82af\u7247\u8bbe\u8ba1\u53ca\u6570\u636e\u5206\u6790\u8f6f\u4ef6\u7cfb\u7edf\u3002\u52a0\u5feb\u57fa\u56e0\u6d4b\u5e8f\u3001\u5206\u6790\u3001\u89e3\u8bfb\u7b49\u6280\u672f\u548c\u4ea7\u54c1\u7684\u5e94\u7528\u8bd5\u70b9\u793a\u8303\u3002<\/div>\n
\u7cbe\u51c6\u533b\u7597\uff1a\u79ef\u6781\u63a8\u52a8\u4e34\u5e8a\u533b\u7597\u6a21\u5f0f\u7531\u4e8b\u540e\u6cbb\u7597\u5411\u7cbe\u51c6\u9884\u9632\u8f6c\u53d8\uff0c\u52a0\u5feb\u6784\u5efa\u8f90\u5c04\u5168\u56fd\u7684\u7cbe\u51c6\u533b\u5b66\u8054\u5408\u4f53\u3002\u52a0\u5feb\u7ec4\u5efa\u7b26\u5408\u56fd\u9645\u6807\u51c6\u7684\u7cbe\u51c6\u533b\u7597\u4e34\u5e8a\u8f6c\u5316\u673a\u6784\uff0c\u7ed3\u5408\u4e34\u5e8a\u5e72\u9884\u5f62\u6210\u7cbe\u51c6\u9632\u6cbb\u65b9\u6848\u548c\u4e34\u5e8a\u5b9e\u8df5\u8def\u5f84\uff0c\u63a2\u7d22\u4ea7\u3001\u5b66\u3001\u7814\u3001\u533b\u534f\u540c\u521b\u65b0\u7684\u7cbe\u51c6\u533b\u7597\u53d1\u5c55\u65b0\u6a21\u5f0f\u3002<\/div>\n
\u667a\u6167\u533b\u7597\uff1a\u8bd5\u70b9\u53d1\u5c55\u201c\u4e92\u8054\u7f51+\u201d\u62a4\u7406\u3001\u5bb6\u5ead\u533b\u751f\u3001\u6162\u6027\u75c5\u7ba1\u7406\uff0c\u63a2\u7d22\u5efa\u7acb\u201c\u62a4\u58eb\u94f6\u884c\u201d\u65b0\u6a21\u5f0f\u3002\u652f\u6301\u4f01\u4e1a\u4f9d\u6258\u5b9e\u4f53\u533b\u7597\u673a\u6784\u53d1\u5c55\u4e92\u8054\u7f51\u533b\u9662\uff0c\u63a8\u52a8\u4f01\u4e1a\u5efa\u8bbe\u6570\u5b57\u533b\u7597\u521b\u65b0\u4e2d\u5fc3\u3002\u52a0\u5feb\u63a8\u8fdb\u533b\u836f\u6d41\u901a\u9886\u57df\u7684\u7269\u8054\u7f51\u7cfb\u7edf\u5efa\u8bbe\uff0c\u52a0\u5feb\u533b\u836f\u7269\u6d41\u914d\u9001\u4f53\u7cfb\u548c\u7535\u5b50\u5546\u52a1\u53d1\u5c55\uff0c\u6784\u5efa\u8de8\u5730\u533a\u4fe1\u606f\u8d44\u6e90\u7f51\u7edc\u4f53\u7cfb\u3001\u96f6\u552e\u8fde\u9501\u7f51\u4ee5\u53ca\u4e0e\u73b0\u4ee3\u7269\u6d41\u914d\u9001\u8981\u6c42\u76f8\u9002\u5e94\u7684\u4fe1\u606f\u5316\u7cfb\u7edf\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.gz.gov.cn\/zwgk\/fggw\/sfbgtwj\/content\/post_8175866.html<\/div>\n
\u00a0<\/div>\n
\u2756\u57fa\u56e0\u7f16\u8f91\u6216\u53ef\u6cbb\u7597\u6210\u5e74\u4eba\u7126\u8651<\/div>\n
2022\u5e745\u67084\u65e5\uff0c\u4f0a\u5229\u8bfa\u4f0a\u5927\u5b66\u829d\u52a0\u54e5\u5206\u6821\u7684\u7814\u7a76\u4eba\u5458\u5728Science Advances\u520a\u6587\uff0c\u8ba4\u4e3a\u57fa\u56e0\u7f16\u8f91\u53ef\u80fd\u662f\u6cbb\u7597\u9752\u6625\u671f\u9157\u9152\u7684\u6210\u5e74\u4eba\u7126\u8651\u548c\u9152\u7cbe\u4f7f\u7528\u969c\u788d\u7684\u4e00\u79cd\u6f5c\u5728\u65b9\u6cd5\u3002\u6700\u65b0\u7684\u52a8\u7269\u7814\u7a76\u7ed3\u679c\u8868\u660e\uff0c\u8fd9\u79cd\u6301\u7eed\u4e00\u751f\u7684\u8868\u89c2\u9057\u4f20\u91cd\u7f16\u7a0b\u53ef\u901a\u8fc7\u4e00\u79cd\u540d\u4e3aCRISPR-dCas9\u7684\u57fa\u56e0\u7f16\u8f91\u5de5\u5177\u64cd\u7eb5\u6210\u5e74\u5927\u9f20\u6a21\u578b\u4e2dArc\u57fa\u56e0\u7684\u7ec4\u86cb\u767d\u4e59\u9170\u5316\u548c\u7532\u57fa\u5316\u8fc7\u7a0b\uff0c\u4ece\u800c\u4f7f\u57fa\u56e0\u66f4\u6613\u4e8e\u6fc0\u6d3b\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.eurekalert.org\/news-releases\/951755<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Guardant\u53d1\u5e03\u654f\u611f\u5ea6\u8fbe91%\u7684\u764c\u75c7\u65e9\u7b5b\u4ea7\u54c1<\/div>\n
2022\u5e745\u67082\u65e5\uff0cGuardant Health\u516c\u53f8\u5ba3\u5e03\uff0c\u4e00\u6b3e\u540d\u4e3aShield\uff0c\u7528\u4e8e\u5728\u5177\u6709\u666e\u901a\u98ce\u9669\u7684\u6210\u4eba\u4e2d\u53d1\u73b0\u65e9\u671f\u7ed3\u76f4\u80a0\u764c\u5148\u5146\u7684\u8840\u68c0\u4e0a\u5e02\uff0c\u8fd9\u662f\u8be5\u516c\u53f8\u63a8\u51fa\u7684\u9996\u6b3e\u57fa\u4e8e\u8840\u68c0\u7684\u65e9\u671f\u7ed3\u76f4\u80a0\u764c\u7b5b\u67e5\u68c0\u6d4b\u3002\u636e\u6089\uff0cShield\u68c0\u6d4b\u662f\u4e00\u6b3e\u57fa\u4e8e\u68c0\u9a8c\u8840\u6db2\u4e2d\u7684\u80bf\u7624\u91ca\u653e\u7684\u6e38\u79bbDNA\u7247\u6bb5\uff0c\u53d1\u73b0\u65e9\u671f\u764c\u75c7\u8ff9\u8c61\u7684\u7b5b\u67e5\u624b\u6bb5\uff0c\u5bf9\u7ed3\u76f4\u80a0\u764c\u8868\u73b0\u51fa91%\u7684\u654f\u611f\u5ea6\uff0c\u5728\u6b63\u5e38\u6837\u672c\u4e2d\u8868\u73b0\u51fa92%\u7684\u7279\u5f02\u6027\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/guardanthealth.com\/<\/div>\n
\u5b8f\u89c2\u73af\u5883<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u82f1\u7f8e\u6700\u65b0\u62a5\u544a\u5206\u6790\u591a\u56fd\u51fa\u73b0\u4e0d\u660e\u75c5\u56e0\u513f\u7ae5\u809d\u708e\u6216\u6765\u81ea\u817a\u75c5\u6bd2<\/div>\n
2022\u5e745\u67087\u65e5\uff0c\u7f8e\u56fd\u75be\u75c5\u4e0e\u9884\u9632\u4e2d\u5fc3\u62a5\u544a\u4e86\u5bf9\u7f8e\u56fd\u51fa\u73b0\u7684\u539f\u56e0\u4e0d\u660e\u7684\u6025\u6027\u513f\u7ae5\u809d\u708e\u75c5\u4f8b\u7684\u7814\u7a76\u8fdb\u5c55\u3002\u65e5\u524d\uff0c\u82f1\u56fd\u536b\u751f\u5b89\u5168\u5c40\u4e5f\u53d1\u5e03\u4e86\u82f1\u56fd\u6025\u6027\u809d\u708e\u513f\u7ae5\u75c5\u4f8b\u7684\u62a5\u544a\uff0c\u62a5\u544a\u8be6\u7ec6\u5206\u6790\u4e86\u75c5\u4f8b\u60c5\u51b5\u5e76\u63d0\u51fa\u4e86\u53d1\u75c5\u539f\u56e0\u5047\u8bf4\u3002\u68c0\u6d4b\u53d1\u73b0\u6700\u5e38\u89c1\u7684\u75c5\u539f\u4f53\u4e3a\u817a\u75c5\u6bd2\uff0c\u76ee\u524d\u7684\u4e3b\u8981\u5047\u8bf4\u4e5f\u662f\u8ba4\u4e3a\u8be5\u79cd\u513f\u7ae5\u6025\u6027\u809d\u708e\u662f\u7531\u4e8e\u666e\u901a\u817a\u75c5\u6bd2\u611f\u67d3\u5f15\u8d77\u7684\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u4ece\u60a3\u8005\u83b7\u5f97\u7684\u809d\u7ec4\u7ec7\u4e2d\uff0c\u5e76\u672a\u5728\u809d\u7ec6\u80de\u4e2d\u53d1\u73b0\u817a\u75c5\u6bd2\u7684\u5b58\u5728\u3002\u817a\u75c5\u6bd2\u7a76\u7adf\u662f\u5982\u4f55\u5f15\u53d1\u708e\u75c7\u7684\uff0c\u76ee\u524d\u5c1a\u672a\u53ef\u77e5\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/assets.publishing.service.gov.uk\/government\/uploads\/system\/uploads\/attachment_data\/file\/1073704\/acute-hepatitis-technical-briefing-2.pdf#page6<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u5f18\u57fa\u751f\u7269\u76846\u9879AAV\u57fa\u56e0\u7597\u6cd5\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u83b7\u53d7\u7406<\/div>\n
2022\u5e745\u67087\u65e5\uff0c\u5f18\u57fa\u751f\u7269\u7533\u62a5\u76846\u9879\u201cKH631\u773c\u7528\u6ce8\u5c04\u6db2\u201dAAV\u57fa\u56e0\u7597\u6cd5\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u83b7\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u836f\u54c1\u8bc4\u5ba1\u4e2d\u5fc3\uff08CDE\uff09\u53d7\u7406\uff0c\u7528\u4e8e\u6cbb\u7597\u6e7f\u6027\u5e74\u9f84\u76f8\u5173\u6027\u9ec4\u6591\u53d8\u6027\uff08nAMD\uff09\uff0c\u662f\u5177\u6709\u81ea\u4e3b\u77e5\u8bc6\u4ea7\u6743\u76841\u7c7b\u751f\u7269\u65b0\u836f\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cde.org.cn\/main\/xxgk\/listpage\/9f9c74c73e0f8f56a8bfbc646055026d<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u7f8e\u56fd\u53d1\u5e0312 \u79cd\u53ef\u80fd\u5f71\u54cd\u533b\u7597\u5065\u5eb7\u7684\u65b0\u5174\u57fa\u56e0\u548c\u7ec6\u80de\u6cbb\u7597\u6280\u672f<\/div>\n
2022\u5e745\u67084\u65e5\uff0c\u7f8e\u56fd\u6700\u5927\u7684\u5b66\u672f\u7814\u7a76\u4f01\u4e1aMass General Brigham\u5728Disruptive Dozen\u4e0a\u5ba3\u5e03\u4e86\u672a\u6765\u51e0\u5e74\u5185\u53ef\u80fd\u5f71\u54cd\u533b\u7597\u5065\u5eb7\u768412\u79cd\u65b0\u5174\u57fa\u56e0\u548c\u7ec6\u80de\u6cbb\u7597 (GCT) \u6280\u672f\u3002Disruptive Dozen\u662f5\u6708\u5728\u6ce2\u58eb\u987f\u4e3e\u884c\u7684\u4e16\u754c\u533b\u5b66\u521b\u65b0\u8bba\u575b\u7684\u4e00\u90e8\u5206\uff0c\u7531\u4e34\u5e8a\u4e13\u5bb6\u3001\u884c\u4e1a\u9886\u5bfc\u8005\u548c\u98ce\u9669\u6295\u8d44\u8005\u7ec4\u6210\uff0c\u63a2\u8ba8\u5982\u4f55\u63a8\u8fdb GCT \u6280\u672f\u4ee5\u9020\u798f\u5168\u7403\u60a3\u8005\u3002<\/div>\n
\u4ee5\u4e0b\u4e3a12\u79cd\u65b0\u5174\u57fa\u56e0\u548c\u7ec6\u80de\u6cbb\u7597\u6280\u672f\uff1a<\/div>\n
1. \u4fee\u590d\u53d7\u635f\u57fa\u56e0\u6062\u590d\u89c6\u529b\uff1a<\/div>\n
\u5927\u7ea6 200 \u4e2a\u57fa\u56e0\u4e0e\u89c6\u529b\u969c\u788d\u76f4\u63a5\u76f8\u5173\u3002\u5728\u8fc7\u53bb\u7684\u51e0\u5e74\u91cc\uff0c\u51fa\u73b0\u4e86\u4e00\u79cd\u6709\u671b\u8ba9\u5931\u660e\u7684\u4eba\u6062\u590d\u89c6\u529b\u7684\u5206\u5b50\u4fee\u590d\u6cd5\u3002\u8fd9\u79cd\u88ab\u79f0\u4e3a CRISPR-Cas-9 \u57fa\u56e0\u7f16\u8f91\u7684\u65b9\u6cd5\u4e3a\u6cbb\u7597\u4e0d\u9002\u5408\u4f20\u7edf\u57fa\u56e0\u6cbb\u7597\u7684\u9057\u4f20\u5f62\u5f0f\u7684\u89c6\u529b\u4e27\u5931\u4ee5\u53ca\u8bb8\u591a\u5176\u4ed6\u533b\u5b66\u75be\u75c5\u6253\u5f00\u5927\u95e8\u3002\u76ee\u524d\u79d1\u5b66\u5bb6\u6b63\u5728\u8fdb\u884c\u8bc4\u4f30CRISPR-Cas 9 \u57fa\u56e0\u7f16\u8f91\u7597\u6cd5\u6cbb\u7597\u4e25\u91cd\u7684\u513f\u7ae5\u5931\u660e\uff08 Leber \u5148\u5929\u6027\u9ed1\u8499 10 \u578b\uff0c\u76ee\u524d\u5c1a\u65e0\u6cbb\u7597\u65b9\u6cd5\uff09\u7684\u6cbb\u7597\u5b9e\u9a8c\uff0c\u5c3d\u7ba1\u8fd9\u79cd\u6cbb\u7597\u4ecd\u5904\u4e8e\u5b9e\u9a8c\u9636\u6bb5\uff0c\u4f46\u5b83\u662f\u7b2c\u4e00\u4e2a\u57fa\u4e8e CRISPR-Cas-9\u7684\u4f53\u5185\u836f\u7269\uff0c\u5177\u6709\u5386\u53f2\u610f\u4e49\u3002\u7c7b\u4f3c\u53ef\u7ea0\u6b63\u8840\u7ec6\u80de\u5185\u57fa\u56e0\u7684\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5\u4e5f\u6b63\u5728\u5f00\u53d1\u4e2d\u3002<\/div>\n
2. \u589e\u52a0\u4f9b\u4f53\u5668\u5b98\u4f9b\u5e94\u7684\u57fa\u56e0\u7f16\u8f91\u89e3\u51b3\u65b9\u6848<\/div>\n
\u4ec5\u5728\u7f8e\u56fd\uff0c\u5c31\u6709\u8d85\u8fc7\u5341\u4e07\u4eba\u7b49\u5f85\u7740\u633d\u6551\u751f\u547d\u7684\u5668\u5b98\u79fb\u690d\u624b\u672f\u3002\u4f46\u7531\u4e8e\u4f9b\u4f53\u5668\u5b98\u4f9b\u5e94\u4e0d\u8db3\u5bfc\u81f4\u7b49\u5f85\u65f6\u95f4\u5ef6\u957f\uff0c\u56e0\u6b64\u8bb8\u591a\u60a3\u8005\u5728\u5668\u5b98\u6350\u732e\u524d\u5c31\u5df2\u7ecf\u6b7b\u4ea1\u4e86\u3002\u5e94\u5bf9\u8fd9\u573a\u5371\u673a\u7684\u552f\u4e00\u53ef\u9884\u89c1\u7684\u89e3\u51b3\u65b9\u6848\u662f\u5f02\u79cd\u79fb\u690d\u2014\u2014\u4ece\u52a8\u7269\u8eab\u4e0a\u91c7\u96c6\u5668\u5b98\u5e76\u5c06\u5176\u690d\u5165\u4eba\u7c7b\u60a3\u8005\u4f53\u5185\u3002\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u7684\u8fdb\u6b65\u4f7f\u5220\u9664\u3001\u63d2\u5165\u6216\u66ff\u6362\u57fa\u56e0\u53d8\u5f97\u76f8\u5bf9\u5bb9\u6613\u548c\u7cbe\u786e\u3002\u8fd9\u79cd\u5206\u5b50\u5de5\u7a0b\u53ef\u4ee5\u907f\u5f00\u4eba\u7c7b\u514d\u75ab\u7cfb\u7edf\uff0c\u8be5\u7cfb\u7edf\u975e\u5e38\u64c5\u957f\u8bc6\u522b\u5916\u6765\u7ec4\u7ec7\u5e76\u5f15\u53d1\u6392\u65a5\u53cd\u5e94\u3002\u5728\u8fc7\u53bb\u7684 20 \u5e74\u91cc\uff0c\u79d1\u5b66\u5bb6\u4eec\u4e00\u76f4\u81f4\u529b\u4e8e\u8bbe\u8ba1\u6210\u529f\u7684\u57fa\u56e0\u7f16\u8f91\u7b56\u7565\uff0c\u4f7f\u732a\u7684\u5668\u5b98\u4e0e\u4eba\u7c7b\u517c\u5bb9\u3002\u5728\u8fc7\u53bb\u7684\u4e00\u5e74\u91cc\uff0c\u8be5\u9886\u57df\u53c8\u5411\u524d\u8fc8\u51fa\u4e86\u4e00\u5927\u6b65\uff1a\u5c06\u57fa\u56e0\u7f16\u8f91\u7684\u732a\u5668\u5b98\uff0c\u5305\u62ec\u5fc3\u810f\u548c\u80be\u810f\uff0c\u79fb\u690d\u5230\u4eba\u7c7b\u4f53\u5185\u3002\u867d\u7136\u5728\u5f02\u79cd\u79fb\u690d\u6210\u4e3a\u73b0\u5b9e\u4e4b\u524d\u9700\u8981\u8fdb\u884c\u5e7f\u6cdb\u7684\u4e34\u5e8a\u6d4b\u8bd5\uff0c\u4f46\u73b0\u5728\u770b\u6765\uff0c\u8fd9\u4e2a\u672a\u6765\u4f3c\u4e4e\u89e6\u624b\u53ef\u53ca\u3002<\/div>\n
3. \u514b\u670d\u5e38\u89c1\u5931\u660e\u5f62\u5f0f\u7684\u7ec6\u80de\u7597\u6cd5<\/div>\n
\u773c\u775b\u4e00\u76f4\u662f\u5f00\u521b\u57fa\u56e0\u7597\u6cd5\u7684\u8bd5\u9a8c\u573a\uff0c\u4e5f\u63a8\u52a8\u4e86\u65b0\u7684\u57fa\u4e8e\u7ec6\u80de\u7684\u7597\u6cd5\uff0c\u8fd9\u4e9b\u7597\u6cd5\u53ef\u4ee5\u6062\u590d\u89c6\u529b\uff0c\u901a\u8fc7\u66ff\u6362\u5df2\u7ecf\u4e22\u5931\u6216\u53d7\u4f24\u7684\u5173\u952e\u7ec6\u80de\u6765\u63d0\u4f9b\u529f\u80fd\u6027\u6cbb\u7597\u3002\u4e00\u79cd\u65b9\u6cd5\u6d89\u53ca\u6765\u81ea\u89c6\u7f51\u819c\u7684\u5e72\u7ec6\u80de\uff0c\u8fd9\u4e9b\u5e72\u7ec6\u80de\u53ef\u4ee5\u4ea7\u751f\u79f0\u4e3a\u5149\u611f\u53d7\u5668\u7684\u5149\u654f\u7ec6\u80de\uff0c\u8fd9\u662f\u5065\u5eb7\u89c6\u529b\u6240\u5fc5\u9700\u7684\u3002\u79d1\u5b66\u5bb6\u4eec\u6b63\u5728\u5229\u7528\u89c6\u7f51\u819c\u5e72\u7ec6\u80de\u5f00\u53d1\u6cbb\u7597\u65e0\u6cd5\u6cbb\u6108\u7684\u773c\u90e8\u75be\u75c5\uff0c\u5305\u62ec\u8272\u7d20\u6027\u89c6\u7f51\u819c\u708e\u3002\u7531\u4e8e\u514d\u75ab\u7cfb\u7edf\u4e0d\u50cf\u8eab\u4f53\u5176\u4ed6\u90e8\u4f4d\u90a3\u6837\u79ef\u6781\u5730\u5de1\u89c6\u773c\u775b\uff0c\u56e0\u6b64\u53ef\u4ee5\u5c06\u6765\u81ea\u65e0\u5173\u5065\u5eb7\u4f9b\u4f53\u7684\u89c6\u7f51\u819c\u5e72\u7ec6\u80de\u79fb\u690d\u5230\u89c6\u529b\u969c\u788d\u60a3\u8005\u4f53\u5185\u3002\u5176\u4ed6\u8fdb\u5c55\u5305\u62ec\u5229\u7528\u60a3\u8005\u81ea\u8eab\u7ec6\u80de\u7684\u7ec6\u80de\u7597\u6cd5\uff0c\u4f8b\u5982\u6765\u81ea\u8840\u6db2\u6216\u76ae\u80a4\u7684\u7ec6\u80de\uff0c\u53ef\u4ee5\u8f6c\u5316\u4e3a\u4f53\u5185\u51e0\u4e4e\u4efb\u4f55\u7ec6\u80de\u7c7b\u578b\uff0c\u5305\u62ec\u89c6\u7f51\u819c\u7ec6\u80de\u3002\u53e6\u4e00\u79cd\u6b63\u5728\u6d4b\u8bd5\u7684\u65b0\u7597\u6cd5\u5229\u7528\u6765\u81ea\u60a3\u8005\u5065\u5eb7\u773c\u775b\u7684\u5e72\u7ec6\u80de\u6765\u4fee\u590d\u53e6\u4e00\u53ea\u773c\u775b\u53d7\u5f71\u54cd\u7684\u89d2\u819c\u3002<\/div>\n
4. \u5229\u7528 RNA \u7684\u529b\u91cf\u6cbb\u7597\u8111\u764c<\/div>\n
RNA\u4ee5\u5176\u8f85\u52a9\u529f\u80fd\u800c\u5e7f\u4e3a\u4eba\u77e5\uff0c\u5b83\u5c06\u4fe1\u606f\u4ece\u7ec6\u80de\u7684\u4e00\u4e2a\u90e8\u5206\u4f20\u9012\u5230\u53e6\u4e00\u4e2a\u90e8\u5206\u4ee5\u5236\u9020\u86cb\u767d\u8d28\u3002\u4f46\u79d1\u5b66\u5bb6\u4eec\u73b0\u5728\u8ba4\u8bc6\u5230 RNA \u5728\u751f\u7269\u5b66\u4e2d\u53d1\u6325\u7740\u66f4\u91cd\u8981\u7684\u4f5c\u7528\uff0c\u5e76\u6b63\u5728\u6316\u6398\u5176\u9690\u85cf\u7684\u6f5c\u529b\uff0c\u4e3a\u4e00\u7cfb\u5217\u75be\u75c5\u521b\u9020\u6709\u6548\u7684\u65b0\u7597\u6cd5\uff0c\u5305\u62ec\u4e00\u79cd\u79f0\u4e3a\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u7684\u7834\u574f\u6027\u8111\u764c\u3002\u8fd9\u79cd\u764c\u75c7\u6cbb\u7597\u8d77\u6765\u6781\u5177\u6311\u6218\u6027\uff0c\u800c\u4e14\u9002\u5e94\u6027\u5f88\u5f3a\u3002\u9776\u5411 RNA \u6216\u6a21\u62df\u5176\u6d3b\u6027\u7684\u65b0\u65b9\u6cd5\u53ef\u80fd\u4f1a\u6709\u5e0c\u671b\u3002\u4e00\u4e2a\u56e2\u961f\u786e\u5b9a\u4e86\u4e09\u4e2a microRNA\uff0c\u5b83\u4eec\u5728\u5065\u5eb7\u795e\u7ecf\u5143\u4e2d\u8d77\u91cd\u8981\u4f5c\u7528\uff0c\u4f46\u5728\u8111\u764c\u53d1\u5c55\u65f6\u4f1a\u4e22\u5931\u3002\u8fd9\u4e9b microRNA \u53ef\u4ee5\u62fc\u63a5\u6210\u4e00\u4e2a\u5355\u5143\uff0c\u5e76\u4f7f\u7528\u75c5\u6bd2\u4f20\u9012\u5230\u5927\u8111\u4e2d\u3002\u5bf9\u5c0f\u9f20\u7684\u521d\u6b65\u7814\u7a76\u8868\u660e\uff0c\u8fd9\u79cd\u6cbb\u7597\u65b9\u6cd5\u53ef\u4ee5\u4f7f\u80bf\u7624\u66f4\u5bb9\u6613\u53d7\u5230\u73b0\u6709\u6cbb\u7597\u65b9\u6cd5\u7684\u5f71\u54cd\uff0c\u5305\u62ec\u5316\u7597\u3002\u53e6\u4e00\u4e2a\u56e2\u961f\u4e5f\u5728\u63a2\u7d22\u4e00\u79cd\u53eb\u505amiR-10b\u7684microRNA\u3002\u963b\u65ad\u5176\u6d3b\u6027\u4f1a\u5bfc\u81f4\u80bf\u7624\u7ec6\u80de\u6b7b\u4ea1\u3002\u73b0\u5728\uff0c\u79d1\u5b66\u5bb6\u4eec\u6b63\u5728\u52aa\u529b\u5f00\u53d1\u4e00\u79cd\u9488\u5bf9miR-10b\u7684\u9776\u5411\u6cbb\u7597\u836f\u7269\uff0c\u53ef\u4ee5\u5728\u4e34\u5e8a\u8bd5\u9a8c\u4e2d\u8fdb\u884c\u6d4b\u8bd5\u3002<\/div>\n
5. \u5b9e\u73b0\u57fa\u56e0\u7597\u6cd5\u6cbb\u7597\u8111\u90e8\u75be\u75c5\u7684\u524d\u666f<\/div>\n
\u57fa\u56e0\u7597\u6cd5\u5bf9\u4e25\u91cd\u4e14\u76ee\u524d\u65e0\u6cd5\u6cbb\u6108\u7684\u75be\u75c5\uff0c\u5305\u62ec\u5927\u8111\u548c\u810a\u9ad3\u75be\u75c5\u5177\u6709\u5de8\u5927\u7684\u524d\u666f\u3002\u4f46\u4ecd\u7136\u5b58\u5728\u4e00\u4e9b\u91cd\u5927\u969c\u788d\u3002\u4f8b\u5982\uff0c\u57fa\u56e0\u6cbb\u7597\u8f7d\u4f53AAV\u65e0\u6cd5\u7a7f\u900f\u8840\u8111\u5c4f\u969c\u8fd9\u4e2a\u4e3b\u8981\u7684\u751f\u7269\u969c\u788d\u3002\u73b0\u5728\u7814\u7a76\u4eba\u5458\u6b63\u5728\u8bbe\u8ba1\u53ef\u4ee5\u7a7f\u8fc7\u8840\u8111\u5c4f\u969c\u7684\u65b0\u7248\u672cAAV\u3002\u4f7f\u7528\u5404\u79cd\u5206\u5b50\u7b56\u7565\uff0c\u5c11\u6570\u56e2\u961f\u5df2\u7ecf\u4fee\u6539\u4e86\u75c5\u6bd2\u5468\u56f4\u7684\u86cb\u767d\u8d28\u5916\u58f3\uff0c\u4f7f\u5176\u80fd\u591f\u8fdb\u5165\u5e76\u5728\u5927\u8111\u4e2d\u5e7f\u6cdb\u5206\u5e03\u3002\u8fd9\u4e9b\u7ecf\u8fc7\u4fee\u9970\u7684\u75c5\u6bd2\u8f7d\u4f53\u76ee\u524d\u6b63\u5728\u5f00\u53d1\u4e2d\uff0c\u53ef\u80fd\u4f1a\u5728\u51e0\u5e74\u5185\u5f00\u59cb\u4e34\u5e8a\u8bd5\u9a8c\u3002\u79d1\u5b66\u5bb6\u4eec\u4e5f\u5728\u4fee\u8865AAV\u7684\u5185\u90e8\u673a\u5236\uff0c\u4ee5\u907f\u5f00\u6f5c\u5728\u7684\u6bd2\u6027\u3002\u7528\u4e00\u79cd\u5b89\u5168\u3001\u6709\u6548\u7684\u65b9\u6cd5\u8fdb\u5165\u5927\u8111\u3002<\/div>\n
6. \u4e00\u79cd\u7075\u6d3b\u3001\u53ef\u7f16\u7a0b\u7684\u6297\u75c5\u6bd2\u65b9\u6cd5<\/div>\n
COVID-19 \u5927\u6d41\u884c\u66b4\u9732\u4e86\u5bf9\u5feb\u901f\u90e8\u7f72\u7597\u6cd5\u4ee5\u5bf9\u6297\u65b0\u5174\u75c5\u6bd2\u7684\u5de8\u5927\u9700\u6c42\u3002\u79d1\u5b66\u5bb6\u4eec\u73b0\u5728\u6b63\u5728\u5f00\u53d1\u4e00\u79cd\u65b0\u578b\u7684\u6297\u75c5\u6bd2\u7597\u6cd5\uff0c\u53ef\u4ee5\u901a\u8fc7\u7f16\u7a0b\u6765\u9776\u5411\u4e00\u7cfb\u5217\u4e0d\u540c\u7684\u75c5\u6bd2\u2014\u2014\u4ece\u4f17\u6240\u5468\u77e5\u7684\u4eba\u7c7b\u75c5\u539f\u4f53\uff0c\u5982\u4e19\u578b\u809d\u708e\uff0c\u5230\u90a3\u4e9b\u4e0d\u592a\u719f\u6089\u7684\u75c5\u539f\u4f53\uff0c\u5982\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2 SARS-CoV- 2\uff0c\u8fd9\u79cd\u65b0\u65b9\u6cd5\u5229\u7528\u4e86CRISPR-Cas\u5de5\u5177\u3002\u867d\u7136\u57fa\u4e8e CRISPR \u7684\u7cfb\u7edf\u56e0\u5176\u4fee\u6539\u4eba\u7c7b\u57fa\u56e0\u7684\u80fd\u529b\u800c\u53d7\u5230\u5173\u6ce8\uff0c\u4f46\u5b83\u4eec\u5728\u81ea\u7136\u754c\u4e2d\u7684\u6700\u521d\u76ee\u7684\u662f\u4fdd\u62a4\u7ec6\u83cc\u514d\u53d7\u75c5\u6bd2\u611f\u67d3\u3002\u4f5c\u4e3a\u5bf9\u8fd9\u4e9b\u65e9\u671f\u6839\u6e90\u7684\u56de\u5f52\uff0c\u79d1\u5b66\u5bb6\u4eec\u73b0\u5728\u6b63\u5728\u91c7\u7528 CRISPR \u5de5\u5177\u6765\u5e94\u5bf9\u5404\u79cd\u611f\u67d3\u4eba\u7c7b\u7684\u75c5\u6bd2\u3002\u00a0<\/div>\n
7. \u5728\u884c\u52a8\u4e2d\uff1a\u7ec6\u80de\u7597\u6cd5\u6062\u590d\u80a0\u9053\u8fd0\u52a8<\/div>\n
\u4eba\u4f53\u6d88\u5316\u9053\u6216\u80a0\u9053\u6709\u81ea\u5df1\u7684\u795e\u7ecf\u7cfb\u7edf\u3002\u7b2c\u4e8c\u4e2a\u5927\u8111\u88ab\u79f0\u4e3a\u80a0\u795e\u7ecf\u7cfb\u7edf\uff0c\u7531\u6267\u884c\u5173\u952e\u4efb\u52a1\u7684\u795e\u7ecf\u5143\u548c\u652f\u6301\u7ec6\u80de\u7ec4\u6210\uff0c\u4f8b\u5982\u901a\u8fc7\u80a0\u9053\u79fb\u52a8\u98df\u7269\u3002\u5f53\u80a0\u795e\u7ecf\u5143\u7f3a\u5931\u6216\u53d7\u4f24\u65f6\uff0c\u80a0\u9053\u8fd0\u52a8\u53ef\u80fd\u4f1a\u53d7\u635f\u3002\u73b0\u5728\uff0c\u79d1\u5b66\u5bb6\u4eec\u6b63\u5728\u5f00\u53d1\u4e00\u79cd\u521b\u65b0\u7684\u7ec6\u80de\u66ff\u4ee3\u7597\u6cd5\u6765\u6cbb\u7597\u80a0\u9053\u8fd0\u52a8\u75be\u75c5\u3002\u4f9b\u4f53\u7ec6\u80de\u53ef\u4ee5\u4ece\u60a3\u8005\u81ea\u5df1\u7684\u80a0\u9053\u6216\u66f4\u5bb9\u6613\u83b7\u5f97\u7684\u6765\u6e90\uff08\u4f8b\u5982\u76ae\u4e0b\u8102\u80aa\uff09\u4e2d\u5206\u79bb\u51fa\u6765\u3002\u7136\u540e\u8fd9\u4e9b\u7ec6\u80de\u5728\u5b9e\u9a8c\u5ba4\u4e2d\u57f9\u517b\u5e76\u8bf1\u5bfc\u5f62\u6210\u4ea7\u751f\u80a0\u795e\u7ecf\u5143\u7684\u7956\u7ec6\u80de\u3002\u7814\u7a76\u4eba\u5458\u4e5f\u5728\u8bbe\u8ba1\u201c\u73b0\u6210\u7684\u201d\u65b9\u6cd5\uff0c\u8fd9\u53ef\u4ee5\u4ea7\u751f\u4e0d\u53d7\u514d\u75ab\u7cfb\u7edf\u5f71\u54cd\u7684\u4f9b\u4f53\u7ec6\u80de\u4f9b\u5e94\uff0c\u56e0\u6b64\u53ef\u4ee5\u666e\u904d\u79fb\u690d\u5230\u4e0d\u540c\u7684\u60a3\u8005\u8eab\u4e0a\u3002\u65e9\u671f\u7814\u7a76\u8868\u660e\uff0c\u79fb\u690d\u7684\u80a0\u795e\u7ecf\u5143\u4e5f\u53ef\u4ee5\u5728\u5927\u8111\u4e2d\u5c45\u4f4f\u3002\u8fd9\u610f\u5473\u7740\u8fd9\u4e9b\u9488\u5bf9\u80a0\u9053\u7ec6\u80de\u7597\u6cd5\u7684\u5c1d\u8bd5\u4e5f\u6709\u52a9\u4e8e\u4e3a\u5927\u8111\u548c\u810a\u9ad3\u7ec6\u80de\u7597\u6cd5\u94fa\u5e73\u9053\u8def\u3002<\/div>\n
8. CAR-T\u7ec6\u80de\u7597\u6cd5\u7784\u51c6\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5<\/div>\n
CAR-T\u7ec6\u80de\u5df2\u6210\u4e3a\u67d0\u4e9b\u5f62\u5f0f\u7684\u764c\u75c7\uff0c\u5c24\u5176\u662f\u8840\u764c\u7684\u6709\u6548\u6cbb\u7597\u65b9\u6cd5\u3002\u901a\u8fc7\u91cd\u65b0\u8fde\u63a5\u60a3\u8005\u81ea\u8eab\u7684T\u7ec6\u80de\u4ee5\u8d4b\u4e88\u5b83\u4eec\u6cbb\u7597\u7279\u6027\uff0c\u79d1\u5b66\u5bb6\u4eec\u6b63\u5728\u52aa\u529b\u5f00\u53d1\u9488\u5bf9\u5404\u79cd\u81ea\u8eab\u514d\u75ab\u6027\u75be\u75c5\u7684\u65b0\u578bCAR-T\u7597\u6cd5\u3002\u51e0\u4e2a\u7814\u7a76\u56e2\u961f\u6b63\u5728\u8bbe\u8ba1 CAR-T\u7ec6\u80de\uff0c\u4ee5\u4fbf\u4ed6\u4eec\u80fd\u591f\u5bfb\u627e\u5e76\u7834\u574f\u6709\u5bb3\u7684\u514d\u75ab\u7ec6\u80de\uff0c\u4f8b\u5982\u90a3\u4e9b\u4ea7\u751f\u81ea\u8eab\u6297\u4f53\u7684\u514d\u75ab\u7ec6\u80de\u2014\u2014\u9776\u5411\u548c\u653b\u51fb\u4eba\u4f53\u81ea\u8eab\u7ec4\u7ec7\u7684\u514d\u75ab\u86cb\u767d\u3002<\/div>\n
9. \u518d\u751f\u5185\u8033\u7ec6\u80de\u4ee5\u6cbb\u7597\u542c\u529b\u635f\u5931<\/div>\n
\u4ec5\u5728\u7f8e\u56fd\uff0c\u5c31\u6709\u5927\u7ea6 3700 \u4e07\u4eba\u60a3\u6709\u542c\u529b\u969c\u788d\u3002\u76ee\u524d\u6ca1\u6709\u836f\u7269\u53ef\u4ee5\u963b\u6b62\u3001\u9884\u9632\u751a\u81f3\u9006\u8f6c\u542c\u529b\u635f\u5931\u3002\u79d1\u5b66\u5bb6\u4eec\u6b63\u5728\u7814\u7a76\u4e00\u79cd\u65b0\u7684\u518d\u751f\u65b9\u6cd5\uff0c\u53ef\u4ee5\u6062\u590d\u6b63\u5e38\u542c\u529b\u6240\u9700\u7684\u5185\u8033\u7ec6\u80de\uff0c\u4e3a\u6570\u767e\u4e07\u542c\u529b\u635f\u5931\u60a3\u8005\u5e26\u6765\u5e0c\u671b\u3002\u5065\u5eb7\u7684\u542c\u529b\u9700\u8981\u5185\u8033\u4e2d\u79f0\u4e3a\u6bdb\u7ec6\u80de\u7684\u7279\u6b8a\u7ec6\u80de\uff0c\u8fd9\u4e9b\u7ec6\u80de\u5177\u6709\u7cbe\u7ec6\u7684\u6bdb\u53d1\u72b6\u7a81\u8d77\u3002\u5982\u679c\u7ec6\u80de\u53d7\u635f\u6216\u4e22\u5931\uff0c\u8fd9\u901a\u5e38\u4f1a\u968f\u7740\u5e74\u9f84\u7684\u589e\u957f\u6216\u53cd\u590d\u66b4\u9732\u4e8e\u54cd\u4eae\u7684\u58f0\u97f3\u800c\u53d1\u751f\uff0c\u8eab\u4f53\u65e0\u6cd5\u4fee\u590d\u5b83\u4eec\u3002\u4f46\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4e86\u4e00\u79cd\u6f5c\u5728\u7684\u89e3\u51b3\u65b9\u6cd5\uff0c\u53ef\u4ee5\u523a\u6fc0\u8033\u6735\u4e2d\u73b0\u6709\u7684\u7ec6\u80de\u8fdb\u884c\u8f6c\u5316\u5e76\u4ea7\u751f\u65b0\u7684\u6bdb\u7ec6\u80de\u3002\u79d1\u5b66\u5bb6\u4eec\u73b0\u5728\u6b63\u5728\u52aa\u529b\u6539\u53d8\u8fd9\u79cd\u5206\u5b50\u7b56\u7565\u3002<\/div>\n
10. \u63d0\u4f9b\u57fa\u56e0\u7597\u6cd5\u7684\u65b0\u6280\u672f<\/div>\n
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\u53c2\u8003\u4fe1\u606f>>https:\/\/www.eurekalert.org\/news-releases\/951761<\/div>\n
\u00a0<\/div>\n
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\u553e\u6db2\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\uff082019-nCoV\uff09\u6297\u539f\u68c0\u6d4b\u8bd5\u5242\u76d2(\u80f6\u4f53\u91d1\u6cd5)\u4e34\u5e8a\u8bd5\u9a8c\u2014\u2014\u4e0a\u6d77\u4f70\u82b1\u6df1\u5904\u533b\u7597\u79d1\u6280\u6709\u9650\u516c\u53f8<\/div>\n
\u65b0\u578b\u51a0\u72b6\u75c5\u6bd2\uff08SARS-CoV-2\uff09\u6297\u539f\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08\u80f6\u4f53\u91d1\u6cd5\uff09\u2014\u2014\u4e0a\u6d77\u5e02\u7b2c\u5341\u4eba\u6c11\u533b\u9662<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/fuwu.most.gov.cn\/html\/tztg\/xzxkzx\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u5168\u7403\u9996\u9488\u5965\u5bc6\u514b\u620e\u75ab\u82d7\u4e34\u5e8a\u8bd5\u9a8c\u5728\u676d\u5dde\u63a5\u79cd<\/div>\n
2022\u5e745\u67081\u65e5\uff0c\u7531\u56fd\u836f\u96c6\u56e2\u4e2d\u56fd\u751f\u7269\u5317\u4eac\u751f\u7269\u5236\u54c1\u7814\u7a76\u6240\u7814\u53d1\u7684\u5965\u5bc6\u514b\u620e\u53d8\u5f02\u682a\u65b0\u51a0\u75c5\u6bd2\u706d\u6d3b\u75ab\u82d7\u4e34\u5e8a\u7814\u7a76\uff0c\u6b63\u5f0f\u5728\u6d59\u6c5f\u7701\u676d\u5dde\u5e02\u5b8c\u6210\u7b2c\u4e00\u5242\u63a5\u79cd\u3002\u8fd9\u4e5f\u662f\u5168\u7403\u9996\u652f\u9488\u5bf9\u5965\u5bc6\u514b\u620e\u53d8\u5f02\u682a\u8fdb\u5165\u4e34\u5e8a\u8bd5\u9a8c\u7684\u65b0\u51a0\u75c5\u6bd2\u706d\u6d3b\u75ab\u82d7\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.stdaily.com\/index\/kejixinwen\/202205\/9e8b866c3c06485a8b71582a52b9a2b4.shtml<\/div>\n
\u00a0<\/div>\n
\u4f1a\u8bae\u63a8\u8350<\/div>\n
\u00a0<\/div>\n
\u2756\u00a02022\u5e74\u7b2c26\u5c4a\u56fd\u9645\u4ea7\u524d\u8bca\u65ad\u4e0e\u6cbb\u7597\u5927\u4f1a\uff08ISPD\uff09\uff0c2022\u5e746\u670819\u81f322\u65e5\uff0c\u52a0\u62ff\u5927\u8499\u7279\u5229\u5c14<\/div>\n
2022\u5e7426\u5c4a\u56fd\u9645\u4ea7\u524d\u8bca\u65ad\u4e0e\u6cbb\u7597\u5927\u4f1a\u5c06\u57282022\u5e746\u670819\u81f322\u65e5\u5728\u52a0\u62ff\u5927\u8499\u7279\u5229\u5c14\u53ec\u5f00\u3002\u672c\u6b21\u4f1a\u8bae\u7531\u56fd\u9645\u4ea7\u524d\u8bca\u65ad\u5b66\u4f1a\uff08ISPD\uff09\u4e3b\u529e\uff0c\u8054\u5408\u56fd\u9645\u533b\u9662\u534f\u4f5c\u4e2d\u5fc3\u7ec4\u7ec7\uff0c\u65e8\u5728\u4fc3\u8fdb\u5168\u7403\u5b55\u524d\u548c\u4ea7\u524d\u9057\u4f20\u5b66\u77e5\u8bc6\uff0c\u5021\u5bfc\u5b55\u524d\u548c\u4ea7\u524d\u9057\u4f20\u3001\u4f26\u7406\u5b9e\u8df5\u7684\u7b5b\u67e5\u3001\u8bca\u65ad\u548c\u6cbb\u7597\uff0c\u63d0\u4f9b\u4e13\u5bb6\u5b66\u8005\u4e4b\u95f4\u7684\u4fe1\u606f\u6c9f\u901a\u548c\u7ecf\u9a8c\u4ea4\u6d41\u826f\u597d\u5e73\u53f0\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.medsci.cn\/meeting\/show.do?id=c004e1c025999a6d<\/div>\n
\u00a0<\/div>\n
\u2756\u00a02022\u5e74\u7b2c72\u5c4a\u7f8e\u56fd\u4eba\u7c7b\u9057\u4f20\u5b66\u4f1a\u5e74\u4f1a\uff08ASHG\uff09\uff0c2022\u5e7410\u670825\u65e5\u81f329\u65e5\uff0c\u6d1b\u6749\u77f6TBD\u573a\u9986<\/div>\n
2022\u5e74\u7b2c72\u5c4a\u7f8e\u56fd\u4eba\u7c7b\u9057\u4f20\u5b66\u4f1a\u5e74\u4f1a\uff08ASHG\uff09\u5c06\u4e8e2022\u5e7410\u670825\u65e5\u81f329\u65e5\u5728\u7f8e\u56fd\u6d1b\u6749\u77f6\u4e3e\u529e\u3002ASHG\u662f\u4e16\u754c\u6700\u5927\u7684\u63a8\u52a8\u4eba\u7c7b\u9057\u4f20\u5b66\u548c\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\u548c\u8f6c\u5316\u9886\u57df\u7684\u4e13\u4e1a\u793e\u533a\uff0c\u65e8\u5728\u9886\u5bfc\u4eba\u7c7b\u9057\u4f20\u5b66\u7684\u7814\u7a76\u3001\u6559\u80b2\u548c\u670d\u52a1\uff0c\u81f4\u529b\u4e8e\u901a\u8fc7\u5353\u8d8a\u7684\u7814\u7a76\u3001\u6559\u80b2\u548c\u5ba3\u4f20\uff0c\u5728\u79d1\u5b66\u5065\u5eb7\u3001\u793e\u4f1a\u9886\u57df\u63a8\u8fdb\u4eba\u7c7b\u9057\u4f20\u5b66\u548c\u57fa\u56e0\u7ec4\u5b66\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.globalconfs.com\/meeting\/29315.html<\/div>\n
\u00a0<\/div>\n
\u6295\u878d\u8d44<\/div>\n
\u00a0<\/div>\n
\u2756\u00a010\u5bb6\u4e0a\u5e02\u57fa\u56e0\u4f01\u4e1aQ1\u8425\u6536\u603b\u8ba1\u8fd1155\u4ebf\u5143\u4eba\u6c11\u5e01<\/div>\n\n
\n
\"RmFicvQBAkgDUiayv8Pzf7WJyFp8RnER6k016N9U9ROD5uKgI4MJaQuncFhhTQy34Yobj1pL5lSZSA6Pv3tRLIuw\"\/<\/figure><\/div>\n\n
\u603b\u7ed3\uff1a<\/div>\n
\u5f97\u76ca\u4e8e\u6db2\u4f53\u6d3b\u68c0\u7684\u5feb\u901f\u53d1\u5c55\uff0cGuardant Health\u5728Q1\u5b63\u5ea6\u7684\u6536\u5165\u76f8\u8f83\u4e0a\u4e00\u5e74\u540c\u6bd4\u589e\u957f22%\uff1b<\/div>\n
\u5355\u7ec6\u80de\u548c\u7a7a\u95f4\u57fa\u56e0\u7ec4\u5b66\u516c\u53f810x Genomics\u3001\u7a7a\u95f4\u751f\u7269\u5b66\u89e3\u51b3\u65b9\u6848\u7684\u516c\u53f8Akoya Biosciences\u4ee5\u53caBionano Genomics \u516c\u53f8\u57282022\u5e74\u7b2c\u4e00\u5b63\u5ea6\u7684\u4e3b\u8981\u6536\u5165\u6765\u81ea\u4e8e\u4ea7\u54c1\u53ca\u670d\u52a1\uff1b<\/div>\n
\u9488\u5bf9\u8425\u6536\u4e0b\u964d\u7684\u539f\u56e0\uff0c\u9664\u53d7\u5230\u65b0\u51a0\u75ab\u60c5\u7684\u5f71\u54cd\u5916\uff0cStandard BioTools\u7684\u8425\u6536\u8fd8\u4e0e\u66f4\u540d\uff08\u539f\u540d\u4e3aFluidigm\uff09\u6709\u5173\uff1b\u4eba\u53e3\u6d4b\u5e8f\u548c\u764c\u75c7\u57fa\u56e0\u7ec4\u5b66\u516c\u53f8Personalis\u5219\u4e3b\u8981\u56e0\u4e3a\u4eba\u53e3\u57fa\u56e0\u7ec4\u5b66\u4e1a\u52a1\u4e0b\u6ed1\uff0c\u56e0\u6b64\u516c\u53f8\u51b3\u5b9a\u8c03\u6574\u6218\u7565\u65b9\u5411\uff0c\u5c06\u4e1a\u52a1\u91cd\u70b9\u8f6c\u5411\u80bf\u7624\u5b66\u548c\u5176\u4ed6\u751f\u7269\u5236\u836f\u6d3b\u52a8\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u51ef\u83b1\u8c31\u5b8c\u6210\u6570\u4ebf\u5143\u65b0\u4e00\u8f6e\u878d\u8d44\uff0c\u52a0\u901f\u53d1\u5c55\u591a\u7ec4\u5b66\u6e90\u5934\u521b\u65b0\u4e34\u5e8a\u4ea7\u54c1\u8d5b\u9053<\/div>\n
\u8fd1\u65e5\uff0c\u676d\u5dde\u51ef\u83b1\u8c31\u7cbe\u51c6\u533b\u7597\u68c0\u6d4b\u6280\u672f\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0\u201c\u51ef\u83b1\u8c31\u201d\uff09\u5ba3\u5e03\u5b8c\u6210\u6570\u4ebf\u5143\u65b0\u4e00\u8f6e\u878d\u8d44\uff0c\u672c\u8f6e\u878d\u8d44\u7531\u4e2d\u91d1\u8d44\u672c\u65d7\u4e0b\u4e2d\u91d1\u4f73\u6cf0\u57fa\u91d1\u9886\u6295\uff0c\u590d\u661f\u533b\u836f\u65d7\u4e0b\u590d\u5065\u8d44\u672c\u3001\u542f\u7533\u521b\u6295\u3001\u897f\u6e56\u79d1\u521b\u6295\u3001\u4e2d\u91d1\u6d66\u6210\u53c2\u4e0e\u6295\u8d44\uff0c\u534e\u5174\u8d44\u672c\u62c5\u4efb\u672c\u8f6e\u878d\u8d44\u7684\u72ec\u5bb6\u8d22\u52a1\u987e\u95ee\u3002\u672c\u6b21\u662f\u51ef\u83b1\u8c31\u7ee72021\u5e74\u5b8c\u6210\u6570\u4ebf\u5143\u7684B\u8f6e\u878d\u8d44\u540e\u5b8c\u6210\u7684\u65b0\u4e00\u8f6e\u878d\u8d44\u3002<\/div>\n
\u5b98\u7f51>>http:\/\/www.calibradx.com\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u82af\u5bbf\u79d1\u6280\u83b7\u6570\u5343\u4e07\u5929\u4f7f+\u8f6e\u6295\u8d44\uff0c\u542f\u660e\u521b\u6295\u9886\u6295<\/div>\n
\u8fd1\u65e5\uff0c\u82af\u5bbf\u79d1\u6280\u83b7\u6570\u5343\u4e07\u5929\u4f7f+\u8f6e\u6295\u8d44\uff0c\u672c\u8f6e\u878d\u8d44\u7531\u542f\u660e\u521b\u6295\u9886\u6295\uff0c\u5cf0\u745e\u8d44\u672c\u3001\u82af\u822a\u8d44\u672c\u8ddf\u6295\u3002\u82af\u5bbf\u79d1\u6280\u662f\u56fd\u5185\u9996\u5bb6\u5f00\u53d1\u5206\u5b50\u82af\u7247\u5f0fDNA \u5408\u6210\u6280\u672f\u7684\u4f01\u4e1a\uff0c\u81f4\u529b\u4e8e\u5229\u7528\u534a\u5bfc\u4f53\u6280\u672f\u8d4b\u80fdDNA\u5408\u6210\u3001mRNA\u5408\u6210\u548c\u5355\u5206\u5b50\u68c0\u6d4b\uff0c\u5c06\u5176\u5e94\u7528\u4e8e\u5b9e\u9a8c\u5ba4\u57fa\u7840\u5e94\u7528\u3001\u5408\u6210\u751f\u7269\u5b66\u548c\u7ec6\u80de\u57fa\u56e0\u6cbb\u7597\u3002<\/div>\n
\u5b98\u7f51>>https:\/\/www.chiplodg.com\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0BioMark Diagnostics\u7b79\u96c6150\u4e07\u52a0\u5143\u7528\u4e8e\u80ba\u764c\u6db2\u4f53\u6d3b\u68c0\u68c0\u6d4b\u6280\u672f\u5546\u4e1a\u5316<\/div>\n
2022\u5e745\u67084\u65e5\uff0c\u6db2\u4f53\u6d3b\u68c0\u516c\u53f8BioMark Diagnostics\u8868\u793a\u5df2\u7b79\u96c6150\u4e07\u52a0\u5143\uff08120\u4e07\u7f8e\u5143\uff09\u4ee5\u52a0\u901f\u5176\u80ba\u764c\u68c0\u6d4b\u6280\u672f\u7684\u5546\u4e1a\u5316\u3002BioMark Diagnostics\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u80bf\u7624\u5b66\u7684\u516c\u53f8\uff0c\u62e5\u6709\u5148\u8fdb\u7684\u5e02\u573a\u524d\u6cbf\u6db2\u4f53\u6d3b\u68c0\u8bca\u65ad\u6280\u672f\uff0c\u65e8\u5728\u6539\u5584\u60a3\u8005\u7684\u6cbb\u7597\u7ed3\u679c\uff0c\u5728\u4ee3\u8c22\u7269\u7684\u68c0\u6d4b\u548c\u5b9a\u91cf\u65b9\u9762\u5df2\u7ecf\u5f00\u53d1\u5e76\u62e5\u6709\u591a\u9879\u77e5\u8bc6\u4ea7\u6743\u3002<\/div>\n
\u5b98\u7f51>>https:\/\/www.biomarkdiagnostics.com\/<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u53d1\u5c55<\/div>\n
\u2756\u00a0Illumina\u88ab\u5224\u4e13\u5229\u4fb5\u6743\u534e\u5927\uff0c\u5e94\u8d54\u507f\u8d8522\u4ebf\u5143\u4eba\u6c11\u5e01<\/div>\n
2022\u5e745\u67086\u65e5\uff0c\u7f8e\u56fd\u7279\u62c9\u534e\u5dde\u8054\u90a6\u966a\u5ba1\u56e2\u8ba4\u5b9a\uff0cIllumina\u7684\u90e8\u5206DNA\u6d4b\u5e8f\u7cfb\u7edf\u7684\u53cc\u901a\u9053\u6d4b\u5e8f\u4fb5\u72af\u534e\u5927\u667a\u9020\uff08CGI\uff09\u7684\u4e24\u9879\u4e13\u5229\uff0cIllumina\u5e94\u5bf9\u6b64\u8d54\u507f3.338\u4ebf\u7f8e\u5143\uff08\u7ea6\u540822\u4ebf\u5143\u4eba\u6c11\u5e01\uff09\u3002\u966a\u5ba1\u56e2\u8ba4\u4e3aIllumina\u7684\u4fb5\u6743\u884c\u4e3a\u662f\u6545\u610f\u7684\uff0c\u56e0\u6b64\u6cd5\u9662\u53ef\u80fd\u4f1a\u9009\u62e9\u5c06\u8d54\u507f\u52a0\u500d\u3002\u88c1\u51b3\u663e\u793a\uff0c\u4e09\u9879Illumina\u8ba4\u4e3aCGI\u4fb5\u6743\u7684\u4e13\u5229\u65e0\u6548\uff0c\u4efb\u4f55\u53ef\u80fd\u7684\u8d54\u507f\u7686\u88ab\u9a73\u56de\u3002\u53d7\u4fb5\u6743\u6848\u5f71\u54cd\uff0c\u622a\u81f32022\u5e745\u67087\u65e5\uff0cIllumina\u80a1\u7968\u5927\u8dcc15.41%\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u793c\u6765\u4e0eGenesis Therapeutics\u5408\u4f5c\uff0c\u5229\u7528AI\u5f00\u53d1\u521b\u65b0\u7597\u6cd5<\/div>\n
2022\u5e745\u67084\u65e5\uff0c\u793c\u6765\u4e0eGenesis Therapeutics\u8fbe\u6210\u5408\u4f5c\uff0c\u5229\u7528Genesis\u7684\u4eba\u5de5\u667a\u80fd\uff08AI\uff09\u836f\u7269\u53d1\u73b0\u5e73\u53f0\uff0c\u9488\u5bf9\u591a\u4e2a\u6cbb\u7597\u9886\u57df\u7684\u591a\u8fbe5\u4e2a\u9776\u70b9\u53d1\u73b0\u521b\u65b0\u7597\u6cd5\u3002\u6839\u636e\u534f\u8bae\uff0c\u4e24\u5bb6\u516c\u53f8\u5c06\u8054\u5408\u4f7f\u7528Genesis\u7684AI\u836f\u7269\u53d1\u73b0\u5e73\u53f0\uff0c\u9488\u5bf93\u4e2a\u9776\u70b9\u5f00\u53d1\u6f5c\u5728\u201cfirst-in-class\u201d\u548c\u201cbest-in-class\u201d\u5019\u9009\u836f\u7269\u3002\u6b64\u5916\uff0c\u793c\u6765\u5177\u6709\u6dfb\u52a0\u4e24\u4e2a\u989d\u5916\u9776\u70b9\u7684\u9009\u62e9\u6743\uff0cGenesis\u6709\u8d44\u683c\u83b7\u5f97\u603b\u8ba1\u9ad8\u8fbe6.7\u4ebf\u7f8e\u5143\u7684\u524d\u671f\u548c\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Allelica\u4e0eInvitae\u5408\u4f5c\u5efa\u7acb\u4e73\u817a\u764c\u591a\u57fa\u56e0\u98ce\u9669\u8bc4\u5206<\/div>\n
2022\u5e745\u67083\u65e5\uff0cAllelica\u5ba3\u5e03\u4e0eInvitae\u5408\u4f5c\u5f00\u53d1\u4e00\u79cd\u4e73\u817a\u764c\u591a\u57fa\u56e0\u98ce\u9669\u8bc4\u5206 (PRS)\uff0c\u4ee5\u4f30\u8ba1\u591a\u8840\u7edf\u5973\u6027\u768410\u5e74\u548c\u7ec8\u751f\u98ce\u9669\uff0c\u4ece\u800c\u66f4\u597d\u4f30\u8ba1\u5973\u6027\u4f55\u65f6\u5e94\u8be5\u5f00\u59cb\u4e73\u817a\u764c\u7b5b\u67e5\u3002\u8ba1\u5212\u5c06\u901a\u8fc7Invitae\u7684\u57fa\u56e0\u7ec4\u5b66\u6570\u636e\u3001\u4e34\u5e8a\u8303\u56f4\u3001\u533b\u5e08\u7f51\u7edc\u548c\u5f00\u53d1\u80fd\u529b\u4e0eAllelica\u4f7f\u7528\u5176\u4e13\u6709\u8f6f\u4ef6\u5de5\u5177\u5206\u6790\u591a\u4e2a\u6570\u636e\u96c6\u7684\u80fd\u529b\u76f8\u7ed3\u5408\u6765\u5f00\u53d1\u548c\u9a8c\u8bc1\u6b64 PRS\u3002<\/div>\n
\u00a0<\/div>\n
\u6280\u672f\u7814\u53d1<\/div>\n
\u2756\u00a0\u57fa\u4e8eCRISPR\u8c31\u7cfb\u8ffd\u8e2a\u65b9\u6cd5\u8bb0\u5f55\u8fc4\u4eca\u6700\u5168\u80ba\u764c\u7ec6\u80de\u8fdb\u5316\u8fc7\u7a0b<\/div>\n
2022\u5e745\u67085\u65e5\uff0c\u7f8e\u56fd\u6000\u7279\u9ed1\u5fb7\u7814\u7a76\u6240\u4e54\u7eb3\u68ee\u00b7\u97e6\u65af\u66fc\u548c\u5408\u4f5c\u8005\u5728Cell\u00a0\u520a\u6587\uff0c\u4ed6\u4eec\u4f7f\u7528\u57fa\u4e8eCRISPR\u7684\u8c31\u7cfb\u8ffd\u8e2a\u65b9\u6cd5\uff0c\u8bb0\u5f55\u4e86\u8fc4\u4eca\u4e3a\u6b62\u6700\u5168\u9762\u7684\u80ba\u764c\u7ec6\u80de\u8fdb\u5316\u8fc7\u7a0b\u3002\u8be5\u65b9\u6cd5\u4f7f\u7528CRISPR\u6280\u672f\u4e3a\u6bcf\u4e2a\u7ec6\u80de\u5d4c\u5165\u53ef\u9057\u4f20\u548c\u53ef\u8fdb\u5316\u7684DNA\u6761\u5f62\u7801\u3002\u6bcf\u6b21\u7ec6\u80de\u5206\u88c2\u65f6\uff0c\u5b83\u7684\u6761\u5f62\u7801\u90fd\u4f1a\u88ab\u8f7b\u5fae\u4fee\u6539\u3002\u5f53\u7814\u7a76\u4eba\u5458\u6700\u7ec8\u6536\u83b7\u539f\u59cb\u7ec6\u80de\u7684\u540e\u4ee3\u65f6\uff0c\u4ed6\u4eec\u5c31\u53ef\u6bd4\u8f83\u7ec6\u80de\u7684\u6761\u5f62\u7801\u6765\u91cd\u5efa\u6bcf\u4e2a\u7ec6\u80de\u7684\u201c\u5bb6\u8c31\u201d\uff0c\u8fd9\u4efd\u8be6\u7ec6\u7684\u80bf\u7624\u75c5\u53f2\u63ed\u793a\u4e86\u5bf9\u80ba\u764c\u5982\u4f55\u8fdb\u5c55\u548c\u8f6c\u79fb\u7684\u65b0\u89c1\u89e3\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.stdaily.com\/index\/kejixinwen\/202205\/f17320115a124880bf6c84ab455c7141.shtml<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u9996\u6279\u751f\u547d\u5168\u666f\u5730\u56fe\u7ed8\u5236\uff0c\u5f00\u542f\u751f\u547d\u7814\u7a76\u65b0\u9886\u57df<\/div>\n
2022\u5e745\u67084\u65e5\uff0c\u6df1\u5733\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u8054\u5408\u591a\u5bb6\u673a\u6784\u7684\u7814\u7a76\u8005\u4eec\u5728Cell\u00a0\u7684\u65f6\u7a7a\u7ec4\u5b66\u8054\u76df\uff08STOC\uff09\u4e13\u9898\u4e0a\u520a\u6587\uff0c\u53d1\u5e03\u57fa\u4e8e\u534e\u5927\u81ea\u4e3b\u7814\u53d1\u7684\u9ad8\u7cbe\u5ea6\u5927\u89c6\u573aStereo-seq\u6280\u672f\u7ed8\u5236\u7684\u5c0f\u9f20\u80da\u80ce\u53d1\u80b2\u65f6\u7a7a\u56fe\u8c31\u76f8\u5173\u6210\u679c\u3002\u6591\u9a6c\u9c7c\u3001\u679c\u8747\u3001\u62df\u5357\u82a5\u65f6\u7a7a\u56fe\u8c31\u76f8\u5173\u6210\u679c\u5728Developmental Cell\u00a0\u53d1\u8868\u3002\u8fd9\u662f\u9996\u6b21\u4ece\u65f6\u95f4\u548c\u7a7a\u95f4\u7ef4\u5ea6\u4e0a\u5bf9\u751f\u547d\u53d1\u80b2\u8fc7\u7a0b\u4e2d\u7684\u57fa\u56e0\u548c\u7ec6\u80de\u53d8\u5316\u8fc7\u7a0b\u8fdb\u884c\u8d85\u9ad8\u7cbe\u5ea6\u89e3\u6790\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/esV55BebTq42o6ErAE0WEg<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u79d1\u5b66\u5bb6\u9996\u6b21\u7cbe\u51c6\u4f7f\u7528\u7535\u6765\u63a7\u5236\u57fa\u56e0\u8868\u8fbe<\/div>\n
2022\u5e745\u67084\u65e5\uff0c\u4f26\u6566\u5e1d\u56fd\u7406\u5de5\u5b66\u9662\u7684\u7814\u7a76\u4eba\u5458\u5728Science Advances\u00a0\u520a\u6587\uff0c\u8868\u793a\u4ed6\u4eec\u5f00\u53d1\u4e86\u4e00\u79cd\u53ef\u4ee5\u901a\u8fc7\u63d0\u4f9b\u548c\u53bb\u9664\u7535\u5b50\u6765\u7cbe\u786e\u6539\u53d8\u57fa\u56e0\u8868\u8fbe\u7684\u65b0\u65b9\u6cd5\u3002\u8be5\u65b9\u6cd5\u6709\u52a9\u4e8e\u5e2e\u52a9\u63a7\u5236\u4f53\u5185\u7684\u751f\u7269\u533b\u5b66\u690d\u5165\u7269\u6216\u751f\u4ea7\u836f\u7269\u548c\u5176\u4ed6\u6709\u7528\u5316\u5408\u7269\u7684\u5927\u578b\u201c\u751f\u7269\u53cd\u5e94\u5668\u201d\u4e2d\u7684\u53cd\u5e94\u3002\u4f7f\u7528\u7535\u6765\u63a7\u5236\u57fa\u56e0\u8868\u8fbe\u5f00\u8f9f\u4e86\u4e00\u4e2a\u65b0\u7684\u7814\u7a76\u9886\u57df\uff0c\u76f8\u8f83\u4e8e\u8fc7\u5f80\u4e0d\u7cbe\u51c6\u7684\u7535\u9057\u4f20\u7cfb\u7edf\uff0c\u6b64\u6b21\u63d0\u51fa\u7684\u5141\u8bb8\u4f7f\u7528\u7ec6\u83cc\u4e2d\u7684\u7535\u523a\u6fc0\u7684\u5de5\u7a0b\u542f\u52a8\u5b50\u7cfb\u7edf\u9996\u6b21\u83b7\u5f97\u51c6\u786e\u6027\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.eurekalert.org\/news-releases\/951517<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u83ab\u83f2\u7279\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u5b9e\u4f53\u7624\u4e2dCAR-T\u7ec6\u80de\u7684\u65b0\u9776\u70b9<\/div>\n
2022\u5e745\u67084\u65e5\uff0c\u83ab\u83f2\u7279\u764c\u75c7\u4e2d\u5fc3\u7684\u7814\u7a76\u4eba\u5458\u5728\u7f8e\u56fd\u764c\u75c7\u7814\u7a76\u534f\u4f1a\u4e0a\u520a\u6587\uff0c\u53d1\u8868\u4e86\u4e00\u79cd\u540d\u4e3aOR2H1\u7684CAR-T\u00a0\u7ec6\u80de\u65b0\u6f5c\u5728\u9776\u6807\u7684\u9274\u5b9a\uff0c\u76ee\u524d\u5df2\u8bc1\u660e\u8be5\u9776\u6807\u53ef\u6291\u5236\u80ba\u90e8\u548c\u5375\u5de2\u80bf\u7624\u7684\u751f\u957f\uff0c\u7814\u7a76\u4eba\u5458\u5e0c\u671b\u8fd9\u4e9b\u521d\u6b65\u7814\u7a76\u80fd\u591f\u4e3a\u5404\u79cd\u5b9e\u4f53\u7624\u60a3\u8005\u5f00\u53d1OR2H1\u00a0CAR-T\u00a0\u7ec6\u80de\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.eurekalert.org\/news-releases\/951685<\/div>\n
\u7f16\u8f91 | \u5f20\u742a<\/div>\n
\u5ba1\u6838 | \u5e03\u4e09\u5c11<\/div>\n
\u6269\u5c55\u9605\u8bfb<\/div>\n
\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5186\u671f<\/a><\/div>\n
\u57fa\u56e0\u79d1\u6280\uff0c\u56fd\u4e4b\u91cd\u5668<\/a><\/div>\n
\u89c5\u5065\u521b\u59cb\u4eba\u548c\u57fa\u56e0\u6167\u521b\u59cb\u4eba\u5bf9\u8c08<\/a><\/div>\n
\u3010\u58f0\u660e\u3011\u4e3a\u4e86\u63a8\u52a8\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u79d1\u6280\u63a8\u5e7f\u3001\u4ea7\u4e1a\u53d1\u5c55\u53ca\u653f\u4ea7\u5b66\u7814\u7528\u8fde\u63a5\uff0c\u57fa\u56e0\u6167\u79c9\u6301\u4e13\u4e1a\u3001\u8d4b\u80fd\u3001\u4e2d\u7acb\u7684\u7acb\u573a\u6536\u96c6\u3001\u5206\u6790\u53ca\u53d1\u5e03\u76f8\u5173\u4fe1\u606f\u3002\u4f46\u7531\u4e8e\u65f6\u6548\u6027\u53ca\u884c\u4e1a\u7279\u6b8a\u6027\uff0c\u6240\u520a\u767b\u5185\u5bb9\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u672a\u7ecf\u8bf4\u660e\u4e0d\u4f5c\u4e3a\u51b3\u7b56\u4f9d\u636e\uff1b\u672c\u6587\u76f8\u5173\u4fe1\u606f\u4e0d\u4ee3\u8868\u57fa\u56e0\u6167\u7684\u89c2\u70b9\uff1b\u57fa\u56e0\u6167\u5e73\u53f0\u520a\u767b\u7684\u539f\u521b\u5185\u5bb9\u7684\u77e5\u8bc6\u4ea7\u6743\u4e3a\u201c\u57fa\u56e0\u6167\u201d\u5546\u6807\u62e5\u6709\u8005\u53ca\u76f8\u5173\u6743\u5229\u4eba\u6240\u6709\uff1b\u6b22\u8fce\u8f6c\u8f7d\uff0c\u8f6c\u8f7d\u8bf7\u7533\u8bf7\u5e76\u6ce8\u660e\u6765\u6e90\u3002\u6b22\u8fce\u4e2a\u4eba\u53ca\u673a\u6784\u6295\u7a3f\u53ca\u5408\u4f5c\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u5173\u4e8e\u57fa\u56e0\u6167\u00a0<\/div>\n
\u57fa\u56e0\u6167\u4e13\u6ce8\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u77e5\u8bc6\u670d\u52a1\u3002\u521b\u59cb\u56e2\u961f\u6df1\u8015\u884c\u4e1a\u4e00\u7ebf\u5341\u4f59\u5e74\uff0c\u79c9\u6301\u201c\u4f7f\u8fde\u63a5\u4ea7\u751f\u4ef7\u503c\uff0c\u7528\u6570\u636e\u770b\u89c1\u672a\u6765\u201d\u7684\u7406\u5ff5\uff0c\u57fa\u4e8e\u4ea7\u4e1a\u667a\u5e93\u548c\u4e13\u4e1a\u5185\u5bb9\uff0c\u63d0\u4f9b\u4ea7\u4e1a\u89c4\u5212\u3001\u884c\u7814\u54a8\u8be2\u3001\u79d1\u6280\u63a8\u5e7f\u7b49\u670d\u52a1\u3002\u8fde\u7eed\u4e94\u5e74\u53d1\u5e03\u884c\u4e1a\u84dd\u76ae\u4e66\uff0c\u88ab\u56fd\u5bb6\u53ca\u7701\u5e02\u7ea7\u4ea7\u4e1a\u62a5\u544a\u6536\u5f55\uff0c\u7ec4\u7ec7\u591a\u5bb6\u5355\u4f4d\u53d1\u5e03\u884c\u4e1a\u5171\u8bc6\u548c\u56e2\u6807\uff0c\u63a8\u52a8\u751f\u547d\u79d1\u6280\u666e\u60e0\u548c\u4ea7\u4e1a\u878d\u5408\u53d1\u5c55\u3002<\/div>\n
\u2606\u00a0\u56fd\u53d1\u6539\u300a\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b\u767d\u76ae\u4e66\u6267\u7b14<\/a><\/div>\n
\u2606\u00a0\u8fde\u7eed\u4e94\u5e74\u53d1\u5e03\u57fa\u56e0\u884c\u4e1a\u84dd\u76ae\u4e66<\/div>\n
\u2606\u00a0\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u80bf\u7624\u6807\u5fd7\u4e13\u4e1a\u59d4\u5458\u4f1a\u6218\u7565\u5408\u4f5c\u5355\u4f4d<\/a><\/div>\n
\u2606\u00a0\u4e2d\u56fd\u9057\u4f20\u5b66\u4f1a\u751f\u7269\u4ea7\u4e1a\u4fc3\u8fdb\u59d4\u5458\u4f1a\u59d4\u5458<\/div>\n
\u2606\u00a0\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5e94\u7528\u5b66\u4f1a\u653f\u7b56\u7814\u7a76\u5e94\u7528\u5206\u4f1a\u5e38\u59d4<\/div>\n
\u2606\u00a0\u6df1\u5733\u5e02\u5065\u5eb7\u4ea7\u4e1a\u53d1\u5c55\u4fc3\u8fdb\u4f1a\u526f\u4f1a\u957f\u5355\u4f4d<\/div>\n
\u2606\u00a0\u53c2\u4e0e\u7ec4\u7ec7\u673a\u6784\u53d1\u5e03\u591a\u9879\u884c\u4e1a\u5171\u8bc6<\/a>\u548c\u56e2\u4f53\u6807\u51c6<\/a><\/div>\n
\u2606\u00a0\u7ec4\u7ec7\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\uff08\u7b79\uff09\u9996\u5c4a<\/a>\u3001\u7b2c\u4e8c\u5c4a<\/a>\u4f1a\u8bae<\/a><\/div>\n
\u2606\u00a0\u4e3b\u529e\u6570\u5b57\u5065\u5eb7\u79c1\u8463\u4f1a<\/a>\u3001\u5927\u6e7e\u533a\u751f\u547d\u5065\u5eb7\u521b\u65b0\u8bba\u575b<\/a><\/div>\n
\u2606\u00a0\u53d7\u9080\u4e3a\u534e\u897f<\/a>\u3001\u56e0\u7f8e\u7eb3<\/a>\u3001\u534e\u5927<\/a>\u3001\u4e0a\u6d77\u4ea4\u5927<\/a>\u7b49\u4f5c\u62a5\u544a<\/div>","protected":false},"excerpt":{"rendered":"

\u805a\u7126 \u4e00\u5468\u70ed\u70b9 1 \u963f\u65af\u5229\u5eb7\u3001Illumina\u7b49\u4f01 …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"close","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[996],"tags":[2201,2200],"class_list":["post-8734","post","type-post","status-publish","format-standard","hentry","category-news","tag-2201","tag-2200"],"_links":{"self":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/8734","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/comments?post=8734"}],"version-history":[{"count":3,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/8734\/revisions"}],"predecessor-version":[{"id":13431,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/8734\/revisions\/13431"}],"wp:attachment":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/media?parent=8734"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/categories?post=8734"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/tags?post=8734"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}