\n![\"RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPX3ftiaUibWSJSvTXIYQ1X6QOTLRAwGEE6IarwLxIDHFZIt56lNmBywKMw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPX3ftiaUibWSJSvTXIYQ1X6QOTLRAwGEE6IarwLxIDHFZIt56lNmBywKMw.jpeg\")
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<\/figure><\/div>\n\n\u57fa\u56e0\u6cbb\u7597\u662f\u201c\u57fa\u56e0\u4ea7\u4e1a2.0\u201d\u5173\u952e\u8d5b\u573a\uff0c\u5c06\u57fa\u56e0\u6280\u672f\u4eceIVD\u8fc8\u5411\u9776\u5411\u836f\u3002\u57fa\u56e0\u6cbb\u7597\u5e76\u975e\u65b0\u8bcd\uff0c\u65e9\u57282004\u5e74\u6211\u56fd\u5c31\u6709\u636e\u79f0\u4e16\u754c\u9996\u4e2a\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1 \u201c\u4eca\u53c8\u751f\u201d\uff08\u57fa\u4e8e\u57fa\u56e0\u91cd\u7ec4\uff09\u4e0a\u5e02\uff0c\u8fd120\u5e74\u8fc7\u53bb\uff0c\u5982\u4eca\u57fa\u56e0\u7f16\u8f91\u6210\u4e3a\u70ed\u70b9\u6280\u672f\uff0c\u6211\u56fd\u5c3d\u7ba1\u5f00\u5c55\u4f17\u591a\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u4f46\u65e0\u4e00\u4f8b\u65b0\u578b\uff08\u57fa\u4e8e\u57fa\u56e0\u7f16\u8f91\u6280\u672f\uff09\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u83b7\u6279\u3002\u5176\u4e2d\u7684\u5dee\u8ddd\u548c\u673a\u4f1a\u6709\u54ea\u4e9b\uff1f<\/div>\n
\u88ab\u57fa\u56e0\u6cbb\u7597\u6cbb\u6108\u7684\u5b69\u5b50<\/div>\n
2018\u5e74\uff0c2\u4e2a\u6708\u5927\u7684\u51ef\u7279\u88ab\u53d1\u73b0\u60a3\u6709\u810a\u9ad3\u6027\u808c\u840e\u7f29\u75c7 (SMA)\u3002<\/div>\n
\u00a0<\/div>\n
SMA\u662f\u4e00\u79cd\u9057\u4f20\u6027\u75be\u75c5\uff0c\u4f1a\u5f71\u54cd\u810a\u9ad3\u548c\u795e\u7ecf\uff0c\u5bfc\u81f4\u808c\u8089\u840e\u7f29\u548c\u865a\u5f31\uff0c\u672a\u7ecf\u6cbb\u7597\u7684\u60a3\u8005\u901a\u5e38\u57282\u5c81\u65f6\u9700\u8981\u5168\u65f6\u547c\u5438\u673a\u652f\u6301\uff0c\u9884\u671f\u5bff\u547d\u901a\u5e38\u4f1a\u7f29\u77ed\u3002\u5e78\u8fd0\u7684\u662f\uff0c2019\u5e747\u6708\uff0cSMA\u57fa\u56e0\u7597\u6cd5\u83b7\u6279FDA\uff0c\u51ef\u7279\u6210\u4e3a\u6ce2\u58eb\u987f\u513f\u7ae5\u533b\u9662\u9996\u4f4d\u63a5\u53d7\u8be5\u7597\u6cd5\u7684\u60a3\u8005\u3002\u6cbb\u7597\u53d6\u5f97\u4e86\u5de8\u5927\u7684\u6210\u529f\uff0c\u51ef\u7279\u7684\u6c9f\u901a\u80fd\u529b\u4e0e\u80ba\u6d3b\u91cf\u4e5f\u63d0\u9ad8\u4e86\u5f88\u591a\uff0c\u810a\u67f1\u5728\u652f\u67b6\u7684\u8f85\u52a9\u4e0b\u4e5f\u4e0d\u518d\u5f2f\u66f2\u3002<\/div>\n
\u00a0<\/div>\n
\u51ef\u7279\u7684\u5988\u5988\u8bf4\uff1a\u201c\u8fd9\u4e09\u5f20\u7167\u7247\u662f\u6700\u5927\u7684\u8861\u91cf\u6807\u51c6\u3002\u7b2c\u4e00\u5e74\uff0c\u51ef\u7279\u53ea\u80fd\u8eba\u5728\u6c99\u6ee9\u4e0a\u73a9\u6c99\u5b50\u3002\u7b2c\u4e8c\u5e74\uff0c\u5979\u53ef\u4ee5\u5750\u8d77\u6765\uff0c\u4f46\u4f9d\u65e7\u9700\u8981\u5916\u529b\u652f\u6301\uff0c\u7b2c\u4e09\u5e74\uff0c\u5979\u53ef\u4ee5\u72ec\u81ea\u4e00\u4eba\u5728\u6d77\u8fb9\u73a9\u800d\u3002\u201d<\/div>\n\n
\n![\"RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXHSD1OyicnwslYazSENd83Gcdw4N6bOlmN9OY5CeQcohjo8LH8brkPaw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXHSD1OyicnwslYazSENd83Gcdw4N6bOlmN9OY5CeQcohjo8LH8brkPaw.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe\uff1a\u51ef\u7279\u57282018\u30012019\u4ee5\u53ca2020\u5e74\u7684\u56fe\u7247\u5bf9\u6bd4\uff08\u6765\u6e90\/boston)<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
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\u00a0<\/div>\n
\u57fa\u56e0\u6cbb\u7597\u7684\u539f\u7406\u662f\u5bf9\u57fa\u56e0\u7684\u4fee\u590d\uff0c\u5305\u62ec\u4f53\u5916\u548c\u4f53\u5185\u4e24\u79cd\u60c5\u51b5\u3002\u5728\u4f53\u5916\uff08\u4f8b\u5982CAR-T\uff09\u5c06\u6cbb\u7597\u6027\u57fa\u56e0\u8f6c\u5bfc\u81f3\u7ec6\u80de\u4e2d\uff0c\u5728\u4f53\u5185\u5c06\u81f4\u75c5\u57fa\u56e0\u7a81\u53d8\u8fdb\u884c\u4fee\u590d\uff08\u4f8b\u5982\u57fa\u56e0\u7f16\u8f91\uff09\u3002\u672c\u7bc7\u9488\u5bf9\u57fa\u4e8e\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u65b0\u578b\u57fa\u56e0\u6cbb\u7597\u6765\u5c55\u793a\uff0c\u4e0d\u6d89\u53caCAR-T\u8303\u7574\u3002<\/div>\n
\u00a0<\/div>\n
\u57fa\u56e0\u7f16\u8f91\u6700\u65e9\u8d77\u6e90\u4e8e1973\u5e74\uff0c\u901a\u8fc7\u57fa\u56e0\u5de5\u7a0b\u4ea7\u751f\u53ef\u4ee5\u62b5\u6297\u6297\u751f\u7d20\u7684\u7ec6\u83cc\uff0c\u57fa\u672c\u539f\u7406\u662f\u5229\u7528\u9176\uff0c\u7279\u522b\u662f\u6838\u9178\u9176\u6765\u5bf9DNA\u94fe\uff08DNA strand\uff09\u8fdb\u884c\u526a\u5207\uff0c\u79fb\u9664\u5df2\u6709\u7684DNA\uff0c\u6216\u8005\u63d2\u5165\u4ee3\u66ff\u7684DNA\u3002<\/div>\n\n
\n![\"RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXJCa5SvfibmGsCNdaLvQ4jxCM1utXUnwTwLvNPHXOV6icPH53uLZcZSTw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXJCa5SvfibmGsCNdaLvQ4jxCM1utXUnwTwLvNPHXOV6icPH53uLZcZSTw.png\")
<\/figure><\/div>\n\n<\/div>\n
<\/figure><\/div>\n\n<\/div>\n\u56fe\uff1a\u57fa\u56e0\u7f16\u8f91\u6d41\u7a0b\uff08\u6765\u6e90\/STNTHEGO\uff09<\/div>\n
<\/div>\n
<\/div>\n
\u4ece1900\u5e74\u4ee3\u540e\u671f\u81f3\u4eca\uff0c\u57fa\u56e0\u7f16\u8f91\u7684\u5de5\u5177\u4e0d\u65ad\u6f14\u5316\uff0c\u4eceZFNs\u3001TALENs\u5230\u5f53\u4e0b\u706b\u70ed\u7684CRISPR\/Cas\u3002\u5c3d\u7ba1\u4ed6\u4eec\u5177\u5907\u5404\u81ea\u7684\u4f18\u7f3a\u70b9\uff08\u5982\u4e0b\u8868\uff09\uff0c\u4f46\u76ee\u524d\u7814\u53d1\u548c\u4ea7\u4e1a\u7684\u7126\u70b9\u662fCRISPR\/Cas\uff0c\u56e0\u4e3a\u8be5\u6280\u672f\u7684\u4f7f\u7528\u907f\u514d\u4e86\u86cb\u767d\u8d28\u5de5\u7a0b\u5f00\u53d1\u9488\u5bf9\u7279\u5b9aDNA\u9776\u5e8f\u5217\u7684\u4f4d\u70b9\u7279\u5f02\u6838\u9178\u9176\u7684\u9700\u8981\uff0c\u7b80\u5316\u4e86\u57fa\u56e0\u7f16\u8f91\u8bbe\u8ba1\u548c\u5b9e\u73b0\u6240\u9700\u7684\u65f6\u95f4\u3002\u4f46\u5728\u5b9e\u9645\u8fd0\u7528\u4e2d\uff0c\u8131\u9776\u73b0\u8c61\u3001Cas9 \u86cb\u767d\u6d3b\u6027\u4ee5\u53ca\u5982\u4f55\u6709\u6548\u5730\u8fdb\u884c\u4f20\u9012\uff0c\u4ecd\u662f\u5728\u4eca\u540e\u7814\u7a76\u4e2d\u9700\u8981\u8003\u8651\u7684\u95ee\u9898\u3002<\/div>\n
<\/div>\n
<\/div>\n
\n\n
\n![\"RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXSBPANrKUmJvNAd1n7MzziaXIoWia74qPjteoqz01sZQhT5OibjJwnCa3A\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXSBPANrKUmJvNAd1n7MzziaXIoWia74qPjteoqz01sZQhT5OibjJwnCa3A.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u88681\uff1a\u4e09\u79cd\u57fa\u56e0\u7f16\u8f91\u5de5\u5177\u5bf9\u6bd4\uff08\u6765\u6e90\/\u57fa\u56e0\u6167\uff09<\/div>\n
\u00a0<\/div>\n
\u9664\u4e86\u4ee5\u4e0a\u4e09\u79cd\uff0c\u8fd1\u5e74\u6765\u7814\u53d1\u51fa\u65b0\u578b\u7684\u57fa\u56e0\u7f16\u8f91\u4ee3\u8868\uff1a<\/div>\n
\u5218\u5982\u8c26\uff08Daivd Liu\uff09\u56e2\u961f\u57282016\u5e74\u5f00\u53d1\u7684\u78b1\u57fa\u7f16\u8f91\uff08BE\uff09\uff0c\u5b9e\u73b0\u5bf9\u7ebf\u7c92\u4f53\u57fa\u56e0\u7ec4\u7684\u7cbe\u51c6\u7f16\u8f91\uff1b2019\u5e74\u8be5\u56e2\u961f\u5f00\u53d1\u5148\u5bfc\u7f16\u8f91\u5de5\u5177\uff08PE\uff09\uff0c\u5b9e\u73b0\u5168\u90e812\u79cd\u53ef\u80fd\u7684\u78b1\u57fa\u8f6c\u5316\u4ee5\u53ca\u591a\u78b1\u57fa\u7684\u7cbe\u51c6\u63d2\u5165\u4e0e\u5220\u9664\uff1b<\/div>\n
\u00a0<\/div>\n
2021\u5e748\u6708\uff0c\u5f20\u950b\u56e2\u961f\u516c\u5f00\u7684\u65b0\u578b\u57fa\u56e0\u7f16\u8f91\u6280\u672fSLEEK\u5b9e\u9a8c\u6570\u636e\uff0c\u8bc1\u660e\u8be5\u6280\u672f\u5b9e\u73b0\u4e86\u5728\u57fa\u56e0\u7ec4\u7684\u7279\u5b9a\u4f4d\u7f6e\u4ee5\u63a5\u8fd1100%\u7684\u6548\u7387\u6572\u5165\u529f\u80fd\u6027\u57fa\u56e0\uff1b<\/div>\n
2022\u5e741\u6708\uff0c\u6211\u56fd\u7684\u8f89\u5927\u57fa\u56e0\u7814\u53d1CRISPR-Cas13RNA\u7f16\u8f91\u5668\u7cfb\u7edf\u2014\u2014Cas13X\uff08\u4e5f\u79f0\u4e3aCas13e\uff09\u548cCas13Y\uff08\u4e5f\u79f0\u4e3aCas13f\uff09\uff0c\u5e95\u5c42\u4e13\u5229\u83b7\u7f8e\u56fd\u4e13\u5229\u5c40\u6388\u6743\u3002<\/div>\n
\u00a0<\/div>\n
\u6b64\u5916\u8fd8\u6709\u4f17\u591a\u4f18\u79c0\u7684\u57fa\u56e0\u7f16\u8f91\u5de5\u5177\uff0c\u7bc7\u5e45\u539f\u56e0\u4e0d\u4e00\u4e00\u4f8b\u4e3e\u3002<\/div>\n
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\u57fa\u4e8e\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u7684\u65b0\u578b\u57fa\u56e0\u6cbb\u7597\u5c1a\u672a\u5f62\u6210\u6210\u719f\u7684\u4ea7\u4e1a\u94fe\uff0c\u9488\u5bf9\u5f53\u524d\u5b9e\u9645\u60c5\u51b5\uff0c\u672c\u6587\u6682\u5c06\u4ea7\u4e1a\u94fe\u7684\u4e0a\u6e38\u5b9a\u4e49\u4e3a\u63d0\u4f9b\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u7684\u516c\u53f8\u548c\u751f\u4ea7\u8f7d\u4f53\u7684\u516c\u53f8\uff1b\u4e2d\u6e38\u662f\u836f\u5382\u4ee5\u53ca\u4e3a\u836f\u5382\u63d0\u4f9b\u5408\u4f5c\u7814\u53d1\u670d\u52a1\u7684CRO\/CDMO\u516c\u53f8\uff1b\u4e0b\u6e38\u4e3a\u533b\u9662\u3002<\/div>\n\n
\n![\"RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXSSFlybr1KAcYPX7KiadmibvO3CGgKhiaXvicp7XrPvBialOx6uIxNb8c1Fw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXSSFlybr1KAcYPX7KiadmibvO3CGgKhiaXvicp7XrPvBialOx6uIxNb8c1Fw.png\")
<\/figure><\/div>\n\n<\/div>\n
<\/figure><\/div>\n\n<\/div>\n\u56fe\uff1a\u57fa\u4e8e\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u7684\u57fa\u56e0\u6cbb\u7597\u4ea7\u4e1a\u94fe\uff08\u6765\u6e90\/\u57fa\u56e0\u6167\uff09<\/div>\n
\u00a0<\/div>\n
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\u8ddd\u79bb\u6211\u56fd\u9996\u4e2a\u65b0\u578b\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u4e0a\u5e02\uff0c\u8fd8\u6709\u591a\u5c11\u8def\u8981\u8d70\uff1f<\/div>\n
\u4ee5\u5168\u7403\u4ee3\u8868\u4f01\u4e1aEditas Medicine\u548c\u6211\u56fd\u4ee3\u8868\u4f01\u4e1a\u8f89\u5927\u57fa\u56e0\u4e3a\u4f8b\uff0c\u901a\u8fc7\u5b83\u4eec\u7684\u8def\u5f84\u548c\u903b\u8f91\uff0c\u601d\u8003\u8ddd\u79bb\u6211\u56fd\u9996\u4e2a\u65b0\u578b\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u4e0a\u5e02\uff0c\u8fd8\u6709\u591a\u5c11\u8def\u8981\u8d70\uff1a<\/div>\n
\u00a0<\/div>\n
\u56fd\u9645\u57fa\u56e0\u7f16\u8f91\u9886\u57df\u7684\u201c\u660e\u661f\u4f01\u4e1a\u201d\u2014\u2014Editas Medicine<\/div>\n
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Editas Medicine\u662f\u4e00\u5bb6\u9886\u5148\u7684\u57fa\u56e0\u7ec4\u7f16\u8f91\u516c\u53f8\uff0c\u5176\u521b\u529e\u4eba\u4e4b\u4e00\u662f\u62e5\u6709CRISPR\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u7684\u4e13\u5229\u751f\u7269\u5b66\u5bb6\u5f20\u950b\u3002\u8be5\u516c\u53f8\u4e13\u6ce8\u4e8e\u5c06CRISPR\/Cas9\u548cCRISPR\/Cas12a\u57fa\u56e0\u7ec4\u7f16\u8f91\u7cfb\u7edf\u7684\u529b\u91cf\u548c\u6f5c\u529b\u8f6c\u5316\u4e3a\u5f3a\u5927\u7684\u836f\u7269\u7ba1\u7ebf\u3002\u00a0<\/div>\n
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\n![\"RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPX5OYiaX5E5cfFdU4X8DftHyZrGuYibsZ9r4Y7h6VOYJJegfThww8o9ODw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPX5OYiaX5E5cfFdU4X8DftHyZrGuYibsZ9r4Y7h6VOYJJegfThww8o9ODw.png\")
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<\/figure><\/div>\n\n<\/div>\n\u56fe\uff1aEditas Madicine logo\uff08\u6765\u6e90\/Editas Madicine\uff09<\/div>\n
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\u5176\u4e0a\u5e02\u4ea7\u54c1EDIT-101\uff0c\u7528\u4e8e\u6cbb\u7597Leber\u5148\u5929\u6027\u9ed1\u849910 (LCA10)\u00a0\u3002\u76ee\u524d\u5df2\u88abFDA\u6388\u4e88\u7f55\u89c1\u513f\u79d1\u75be\u75c5\u548c\u5b64\u513f\u836f\u79f0\u53f7\u548c\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40(EMA)\u7684\u5b64\u513f\u6307\u5b9a\u3002\u5176\u5728\u7814\u836f\u7269\uff0c\u4e3b\u8981\u96c6\u4e2d\u5728\u9488\u5bf9\u773c\u90e8\u7f55\u89c1\u75c5\u3002<\/div>\n
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\n![\"RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXCLZicHC9YGZvx30Cq2quBZ3Giavpciao6a68mzvpWoN7ra1JdaL3VgO8Q\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXCLZicHC9YGZvx30Cq2quBZ3Giavpciao6a68mzvpWoN7ra1JdaL3VgO8Q.png\")
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<\/figure><\/div>\n\n<\/div>\n\u56fe\uff1aEditas-101\u6d41\u7a0b\uff08\u6765\u6e90\/Editas Madicine\uff09<\/div>\n
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\u516c\u53f8\u6210\u7acb\u81f3\u4eca\uff0c\u5171\u53d1\u751f\uff15\u8d77\u603b\u8ba1\u8d85\uff16\u4ebf\u7f8e\u5143\u7684\u878d\u8d44\u3002<\/div>\n
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\n![\"RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXexuUFaS1FGYyLbl7k4hic0SJET5UziaFwFVbE4BXaFGNzUSOprzBlBVg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXexuUFaS1FGYyLbl7k4hic0SJET5UziaFwFVbE4BXaFGNzUSOprzBlBVg.png\")
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<\/figure><\/div>\n\n<\/div>\n\u56fe\uff1aEditas Madicine\u7684\u4e94\u8f6e\u878d\u8d44\uff08\u6765\u6e90\/Editas Madicine\uff09<\/div>\n
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\u56fd\u5185\u9996\u4e2a\u7a81\u7834\u6b27\u7f8e\u4e13\u5229\u5c01\u9501\u7684\u57fa\u56e0\u7f16\u8f91\u4f01\u4e1a\u2014\u2014\u8f89\u5927\u57fa\u56e0<\/div>\n
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2018\u5e7410\u6708\uff0c\u8f89\u5927\u57fa\u56e0\u6210\u7acb\u4e8e\u4e0a\u6d77\uff0c\u81f4\u529b\u4e8e\u7f55\u89c1\u75c5\u5355\u57fa\u56e0\u9057\u4f20\u75c5\u53ca\u5a01\u80c1\u4eba\u7c7b\u5065\u5eb7\u7684\u6162\u6027\u75c5\u57fa\u56e0\u66ff\u4ee3\u548c\u57fa\u56e0\u7f16\u8f91\u7b49\u57fa\u56e0\u6cbb\u7597\u836f\u7269\u7684\u7814\u53d1\u548c\u751f\u4ea7\u3002\u8f89\u5927\u57fa\u56e0\u62e5\u6709\u6211\u56fd\u9996\u4e2a\u81ea\u4e3b\u7814\u53d1\u7684\u3001\u5728\u7f8e\u56fd\u83b7\u5f97\u4e13\u5229\u6388\u6743\u7684CRISPR-Cas13\u57fa\u56e0\u7f16\u8f91\u5de5\u5177\uff0c\u7a81\u7834\u4e86\u6b27\u7f8e\u4e13\u5229\u5c01\u9501\u3002\u4e0e\u6b64\u540c\u65f6\uff0c\u8f89\u5927\u57fa\u56e0\u4e5f\u62e5\u6709\u7531\u6765\u81eaMIT\u3001\u8036\u9c81\u3001\u590d\u65e6\u7684\u56e2\u961f\u7ec4\u6210\u9012\u9001\u8f7d\u4f53\u5e73\u53f0\uff0c\u5176\u5f00\u53d1\u7684AAV\u75c5\u6bd2\u8f7d\u4f53\uff0c\u62e5\u6709\u81ea\u4e3b\u4ea7\u6743\u3002<\/div>\n
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\n![\"0?wx_fmt=jpeg\"\/](\"https:\/\/mmbiz.qlogo.cn\/mmbiz_jpg\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXh6qC6cGvbAYH1N5kdMXf6eWzl19ia5afDzDcmicl92l6G9uiasFngeaOw\/0?wx_fmt=jpeg\")
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\u56fe\uff1a\u8f89\u5927\u57fa\u56e0logo\uff08\u6765\u6e90\/\u8f89\u5927\u57fa\u56e0\uff09<\/div>\n
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\u622a\u6b62\u5230\u76ee\u524d\uff0c\u8f89\u5927\u57fa\u56e0\u5171\u5b8c\u62104\u8d77\u603b\u8ba1\u7ea66\u4ebf\u5143\u4eba\u6c11\u5e01\u7684\u878d\u8d44\u3002<\/div>\n
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\n![\"RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXTB9DkObM6qLdEkWI0xjib90KJibRTjwmdxFTuNgq3urYWuQDYFVgAT4Q\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXTB9DkObM6qLdEkWI0xjib90KJibRTjwmdxFTuNgq3urYWuQDYFVgAT4Q.png\")
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\u00a0<\/div>\n
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\n![\"RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXOs5QVhHpM7p2Picz2m7FYicT05xniaUuHpFT6iboEjpoY8jlCosXqVsNxA\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCOEhmiakQrDJJicv1LicuRIPXOs5QVhHpM7p2Picz2m7FYicT05xniaUuHpFT6iboEjpoY8jlCosXqVsNxA.png\")
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\u7b2c\u4e09\u6b65\u5728\u5b8f\u89c2\u653f\u7b56\u4e0a\u3002\u6211\u56fd\u5bf9\u4e8e\u57fa\u56e0\u6cbb\u7597\u7684\u53d1\u5c55\u6301\u9f13\u52b1\u6001\u5ea6\u3002\u4ee5\u4eca\u5e74\u4e3a\u4f8b\uff0c\u6211\u56fd\u5148\u540e\u53d1\u5e03\u201d\u5341\u56db\u4e94\u201c\u751f\u7269\u7ecf\u6d4e\u53d1\u5c55\u89c4\u5212\u3001\u5141\u8bb8\u7f55\u89c1\u75c5\u65b0\u836f7\u5e74\u5e02\u573a\u72ec\u5360\u6743\u3001\u4f53\u5185\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1\u836f\u5b66\u7814\u7a76\u4e0e\u8bc4\u4ef7\u6280\u672f\u6307\u5bfc\u539f\u5219\uff08\u8bd5\u884c\uff09\u7b49\uff0c\u671f\u5f85\u672a\u6765\u6709\u66f4\u591a\u6276\u6301\u653f\u7b56\u51fa\u73b0\uff0c\u4fc3\u8fdb\u884c\u4e1a\u53d1\u5c55\u3002<\/div>\n
\u66f4\u591a\u6df1\u5165\u5206\u6790\u4e0e\u63a2\u7d22\uff0c\u8bf7\u5173\u6ce8\u57fa\u56e0\u6167\u6b63\u5728\u53d1\u8d77\u7684\u300a2022\u57fa\u56e0\u6cbb\u7597\u84dd\u76ae\u4e66\u300b\uff0c\u6211\u4eec\u4e5f\u8bda\u631a\u5730\u9080\u8bf7\u4e1a\u5185\u4e13\u5bb6\u53ca\u673a\u6784\u5408\u4f5c\uff01<\/div>\n
\u00a0<\/div>\n
\u53c2\u8003\u94fe\u63a5>><\/div>\n
1.\u00a0https:\/\/www.bostonoandp.com\/blog\/kates-sma-story-what-makes-ordinary-milestones-extraordinary\/<\/div>\n
2. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8884051\/<\/div>\n
3.\u00a0https:\/\/www.editasmedicine.com\/gene-editing-pipeline\/<\/div>\n
4.\u00a0https:\/\/www.huidagene.com\/pipeline.html<\/div>\n
\u00a0<\/div>\n
\u4f5c\u8005\u4e28\u5f20\u742a\u00a0\u00a0\u6821\u5bf9 | \u5a01\u950b\u00a0\u5ba1\u6838\u00a0| \u5e03\u4e09\u5c11\u00a0\u00a0<\/div>\n
\u9996\u53d1\u4e28\u57fa\u56e0\u6167\u00a0\u00a0\u5173\u952e\u8bcd | \u57fa\u56e0\u6cbb\u7597\uff1b\u57fa\u56e0\u7f16\u8f91<\/div>\n
\u00a0<\/div>\n
\u6269\u5c55\u9605\u8bfb<\/div>\n
\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5No.191<\/a><\/div>\n
\u6838\u9178\u68c0\u6d4b\u4e0d\u6b62\u4e8e\u65b0\u51a0<\/a><\/div>\n
\u751f\u7269\u80b2\u79cd\u4f60\u5fc5\u987b\u77e5\u9053\u7684\u51e0\u4ef6\u4e8b<\/a><\/div>\n
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\u00a0\u5173\u4e8e\u57fa\u56e0\u6167\u00a0<\/div>\n
\u57fa\u56e0\u6167\u4e13\u6ce8\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u77e5\u8bc6\u670d\u52a1\u3002\u521b\u59cb\u56e2\u961f\u6df1\u8015\u884c\u4e1a\u4e00\u7ebf\u5341\u4f59\u5e74\uff0c\u79c9\u6301\u201c\u4f7f\u8fde\u63a5\u4ea7\u751f\u4ef7\u503c\uff0c\u7528\u6570\u636e\u770b\u89c1\u672a\u6765\u201d\u7684\u7406\u5ff5\uff0c\u57fa\u4e8e\u4ea7\u4e1a\u667a\u5e93\u548c\u4e13\u4e1a\u5185\u5bb9\uff0c\u63d0\u4f9b\u4ea7\u4e1a\u89c4\u5212\u3001\u884c\u7814\u54a8\u8be2\u3001\u79d1\u6280\u63a8\u5e7f\u7b49\u670d\u52a1\u3002\u8fde\u7eed\u4e94\u5e74\u53d1\u5e03\u884c\u4e1a\u84dd\u76ae\u4e66\uff0c\u88ab\u56fd\u5bb6\u53ca\u7701\u5e02\u7ea7\u4ea7\u4e1a\u62a5\u544a\u6536\u5f55\uff0c\u7ec4\u7ec7\u591a\u5bb6\u5355\u4f4d\u53d1\u5e03\u884c\u4e1a\u5171\u8bc6\u548c\u56e2\u6807\uff0c\u63a8\u52a8\u751f\u547d\u79d1\u6280\u666e\u60e0\u548c\u4ea7\u4e1a\u878d\u5408\u53d1\u5c55\u3002<\/div>\n
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\u2606\u00a0\u8fde\u7eed\u4e94\u5e74\u53d1\u5e03\u57fa\u56e0\u884c\u4e1a\u84dd\u76ae\u4e66<\/div>\n
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