{"id":8714,"date":"2022-06-13T08:00:00","date_gmt":"2022-06-13T00:00:00","guid":{"rendered":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/06\/13\/999856\/"},"modified":"2026-04-01T11:09:40","modified_gmt":"2026-04-01T03:09:40","slug":"999856","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/06\/13\/999856\/","title":{"rendered":"\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5NO.193"},"content":{"rendered":"

<\/p>\n

\u4e00\u5468\u70ed\u70b9<\/div>\n
1.\u00a0Bluebird\u7684\u57fa\u56e0\u7597\u6cd5\u83b7FDA\u4e13\u5bb6\u59d4\u5458\u4f1a\u5168\u7968\u652f\u6301\uff0c\u7528\u4e8e\u6cbb\u7597\u8f93\u8840\u4f9d\u8d56\u578b\u03b2\u5730\u8d2b<\/div>\n
2.\u00a0\u7f8e\u56e0\u57fa\u56e0\u5f15\u5165\u8fc8\u514b\u751f\u7269\u7b493\u4f4d\u57fa\u77f3\u6295\u8d44\u4eba\uff0c\u8ba4\u8d2d1.485\u4ebf\u5143\u4eba\u6c11\u5e01<\/div>\n
3. \u6211\u56fd\u9996\u4e2aB\u578b\u8840\u53cb\u75c5\u539f\u521b\u9776\u6807\u57fa\u56e0\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u83b7CDE\u53d7\u7406<\/div>\n
4.\u00a0\u521b\u65b0\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5\u52a9\u529b\u964d\u4f4e\u75f4\u5446\u75c7\u76f8\u5173\u86cb\u767d\u7ea640%<\/div>\n
5. \u8fc4\u4eca\u6700\u5927\u9ed1\u7329\u7329\u57fa\u56e0\u7ec4\u56fe\u8c31\u7ed8\u5236\u5b8c\u6210\uff0c\u6709\u52a9\u6253\u51fb\u975e\u6cd5\u8d29\u8fd0\u53ca\u8ffd\u8e2a\u6eaf\u6e90<\/div>\n
6.\u00a0\u6df1\u5733\u51fa\u53f0\u91cd\u8981\u653f\u7b56\u6587\u4ef6\uff0c\u91cd\u70b9\u53d1\u5c55\u7ec6\u80de\u4e0e\u57fa\u56e0\u7b49\u672a\u6765\u4ea7\u4e1a<\/div>\n
\u2026\u2026\uff08\u66f4\u591a\u8be6\u89c1\u57fa\u56e0\u6167\u6bcf\u5468\u7b80\u62a5GeneMail\uff09<\/div>\n
\u00a0<\/div>\n
\u5934\u6761\u8d44\u8baf<\/div>\n
\u2756\u00a0Bluebird\u7684\u57fa\u56e0\u7597\u6cd5\u83b7FDA\u4e13\u5bb6\u59d4\u5458\u4f1a\u5168\u7968\u652f\u6301\uff0c\u7528\u4e8e\u6cbb\u7597\u8f93\u8840\u4f9d\u8d56\u578b\u03b2\u5730\u8d2b<\/div>\n
2022\u5e746\u670811\u65e5\uff0cbluebird bio\u5ba3\u5e03\u5176betibeglogene autotemcel\uff08beti-cel\uff09\u57fa\u56e0\u7597\u6cd5\u83b7\u5f97FDA\u7ec6\u80de\u3001\u7ec4\u7ec7\u548c\u57fa\u56e0\u7597\u6cd5\u54a8\u8be2\u59d4\u5458\u4f1a\u6210\u5458\u7684\u5168\u7968\u652f\u6301\uff0c\u6709\u671b\u6210\u4e3a\u9996\u6b3e\u7f8e\u56fdFDA\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u03b2\u5730\u4e2d\u6d77\u8d2b\u8840\u7684\u6f5c\u5728\u6cbb\u6108\u6027\u57fa\u56e0\u7597\u6cd5\u30026\u670810\u65e5\uff0c\u8be5\u516c\u53f8\u7684elivaldogene autotemcel\uff08eli-cel\uff09\u57fa\u56e0\u7597\u6cd5\u4e5f\u83b7\u5f97FDA\u7ec6\u80de\u3001\u7ec4\u7ec7\u548c\u57fa\u56e0\u7597\u6cd5\u54a8\u8be2\u59d4\u5458\u4f1a\u6210\u5458\u7684\u5168\u7968\u652f\u6301\uff0c\u7528\u4e8e\u6cbb\u7597\u65e9\u671f\u8111\u6027\u80be\u4e0a\u817a\u8111\u767d\u8d28\u8425\u517b\u4e0d\u826f\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/investor.bluebirdbio.com\/news-releases\/news-release-details\/fda-advisory-committee-unanimously-supports-beti-cel-gene<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u7f8e\u56e0\u57fa\u56e0\u5f15\u5165\u8fc8\u514b\u751f\u7269\u7b493\u4f4d\u57fa\u77f3\u6295\u8d44\u4eba\uff0c\u8ba4\u8d2d1.485\u4ebf\u5143\u4eba\u6c11\u5e01<\/div>\n
2022\u5e746\u670810\u65e5\uff0c\u7f8e\u56e0\u57fa\u56e0\u516c\u544a\u5c06\u4e8e2022\u5e746\u670810\u65e5\u81f315\u65e5\u62db\u80a1\uff0c\u62df\u5168\u7403\u53d1\u884c1196.18\u4e07\u80a1\u65b0\u80a1\uff0c\u5176\u4e2d\u9999\u6e2f\u516c\u5f00\u53d1\u552e\u536010%\uff0c\u56fd\u9645\u53d1\u552e\u536090%\uff0c\u53e6\u670915%\u8d85\u989d\u914d\u80a1\u6743\uff0c\u9884\u671fH\u80a1\u5c06\u4e8e2022\u5e746\u670822\u65e5\u4e0a\u5348\u4e5d\u65f6\u6b63(\u9999\u6e2f\u65f6\u95f4)\u5f00\u59cb\u5728\u8054\u4ea4\u6240\u4e70\u5356\u3002\u516c\u53f8\u5df2\u4e0e\u5357\u660c\u91d1\u878d\u3001\u5357\u660c\u5de5\u63a7\u56ed\u533a\u53ca\u8fc8\u514b\u751f\u7269\u8ba2\u7acb\u57fa\u77f3\u6295\u8d44\u534f\u8bae\uff0c\u5408\u8ba1\u8ba4\u8d2d\u91d1\u989d1.485\u4ebf\u5143\u4eba\u6c11\u5e01\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.megagenomics.cn\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u6211\u56fd\u9996\u4e2aB\u578b\u8840\u53cb\u75c5\u539f\u521b\u9776\u6807\u57fa\u56e0\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u83b7CDE\u53d7\u7406<\/div>\n
2022\u5e746\u670810\u65e5\uff0c\u56db\u5ddd\u81f3\u5584\u552f\u65b0\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\uff08\u4ee5\u4e0b\u7b80\u79f0\uff1a\u81f3\u5584\u552f\u65b0\uff09\u81ea\u4e3b\u7814\u53d1\u7684\u57fa\u56e0\u6cbb\u7597\u4ea7\u54c1ZS801\u6ce8\u5c04\u6db2\u7684\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u83b7CDE\u53d7\u7406\uff0c\u7528\u4e8e\u6cbb\u7597B\u578b\u8840\u53cb\u75c5\u3002\u8be5\u836f\u7269\u4e3a\u56fd\u5185\u9996\u4e2aB\u578b\u8840\u53cb\u75c5\u539f\u521b\u9776\u6807\u57fa\u56e0\u836f\u7269\uff0c\u662f\u6211\u56fd\u817a\u76f8\u5173\u75c5\u6bd2\u8f7d\u4f53\uff08rAAV\uff09\u57fa\u56e0\u836f\u7269\u6cbb\u7597\u7684\u91cd\u8981\u91cc\u7a0b\u7891\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cde.org.cn\/main\/xxgk\/listpage\/9f9c74c73e0f8f56a8bfbc646055026d<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u521b\u65b0\u57fa\u56e0\u7f16\u8f91\u7597\u6cd5\u52a9\u529b\u964d\u4f4e\u75f4\u5446\u75c7\u76f8\u5173\u86cb\u767d\u7ea640%<\/div>\n
2022\u5e746\u670810\u65e5\uff0cSeelos Therapeutics\u516c\u53f8\u5ba3\u5e03\uff0c\u5176\u5728\u7814\u7597\u6cd5SLS-004\u5728\u4f53\u5916\u6a21\u578b\u5b9e\u9a8c\u4e2d\u7684\u7814\u7a76\u7ed3\u679c\uff0c\u5728\u4f7f\u7528\u4eba\u7c7b\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u5206\u5316\u5f62\u6210\u7684\u8def\u6613\u4f53\u75f4\u5446\u75c7\uff08DLB\uff09\u4f53\u5916\u6a21\u578b\u4e2d\uff0c\u4e0e\u5bf9\u7167\u7ec4\u76f8\u6bd4\uff0cSLS-004\u80fd\u591f\u5c06SNCA\u7684mRNA\u6c34\u5e73\u964d\u4f4e19%\uff0c\u5e76\u5bfc\u81f4\u03b1\u7a81\u89e6\u6838\u86cb\u767d\u6c34\u5e73\u964d\u4f4e\u7ea640%\u3002\u8fd9\u4e9b\u7ed3\u679c\u5c06\u652f\u6301\u63a8\u52a8SLS-004\u9488\u5bf9DLB\u7684\u8fdb\u4e00\u6b65\u4e34\u5e8a\u524d\u7814\u7a76\u3002<\/div>\n\n
\n
\"0?wx_fmt=jpeg\"\/<\/figure><\/div>\n\n<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/pulse2.com\/seelos-therapeutics-seel-stock-price-why-it-increased-3-68-today\/<\/div>\n<\/p>\n
\u2756\u00a0\u8fc4\u4eca\u6700\u5927\u9ed1\u7329\u7329\u57fa\u56e0\u7ec4\u56fe\u8c31\u7ed8\u5236\u5b8c\u6210\uff0c\u6709\u52a9\u6253\u51fb\u975e\u6cd5\u8d29\u8fd0\u53ca\u8ffd\u8e2a\u6eaf\u6e90<\/div>\n
2022\u5e746\u67087\u65e5\uff0c\u897f\u73ed\u7259\u8fdb\u5316\u751f\u7269\u5b66\u7814\u7a76\u6240\uff08IBE\uff09\u3001\u5fb7\u56fd\u7efc\u5408\u751f\u7269\u591a\u6837\u6027\u7814\u7a76\u4e2d\u5fc3\u3001\u9a6c\u514b\u65af\u00b7\u666e\u6717\u514b\u8fdb\u5316\u4eba\u7c7b\u5b66\u7814\u7a76\u6240\u548c\u83b1\u6bd4\u9521\u5927\u5b66\u7684\u79d1\u5b66\u5bb6\u4eec\u5728Cell\u00a0\u520a\u6587\uff0c\u5ba3\u5e03\u901a\u8fc7\u5bf9800\u4efd\u9ed1\u7329\u7329\u6837\u672c\u4e2d\u7684DNA\u8fdb\u884c\u6d4b\u5e8f\uff0c\u7f16\u5236\u51fa\u4e16\u754c\u4e0a\u8fc4\u4eca\u6700\u5927\u7684\u91ce\u751f\u9ed1\u7329\u7329\u57fa\u56e0\u7ec4\u76ee\u5f55\u3002\u8be5\u56fe\u8c31\u53ef\u4ee5\u6f84\u6e05\u733f\u7c7b\u8fdb\u5316\u53f2\u4e2d\u7684\u76f8\u5173\u95ee\u9898\uff0c\u5e76\u53ef\u7528\u4e8e\u6253\u51fb\u5077\u730e\u8005\u548c\u8d29\u8fd0\u8005\uff0c\u4fdd\u62a4\u9ed1\u7329\u7329\u8fd9\u79cd\u6fd2\u5371\u7269\u79cd\u3002<\/div>\n
<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.stdaily.com\/index\/kejixinwen\/202206\/9eb73bcc414345ef9b3a3ea0f3364954.shtml<\/div>\n<\/p>\n
\u2756\u00a0\u6df1\u5733\u51fa\u53f0\u91cd\u8981\u653f\u7b56\u6587\u4ef6\uff0c\u91cd\u70b9\u53d1\u5c55\u7ec6\u80de\u4e0e\u57fa\u56e0\u7b49\u672a\u6765\u4ea7\u4e1a<\/div>\n
2022\u5e746\u67086\u65e5\uff0c\u6df1\u5733\u51fa\u53f0\u300a\u5173\u4e8e\u53d1\u5c55\u58ee\u5927\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u96c6\u7fa4\u548c\u57f9\u80b2\u53d1\u5c55\u672a\u6765\u4ea7\u4e1a\u7684\u610f\u89c1\u300b\u91cd\u8981\u653f\u7b56\u6587\u4ef6\uff0c\u91cd\u70b9\u57f9\u80b2\u53d1\u5c55\u5305\u542b\u7ec6\u80de\u4e0e\u57fa\u56e0\u5728\u5185\u76848\u5927\u672a\u6765\u4ea7\u4e1a\u3002\u5411\u516c\u4f17\u53f7\u53d1\u9001\u5173\u952e\u8bcd\u201c\u751f\u7269\u533b\u836f\u201d\u3001\u201c\u533b\u7597\u5668\u68b0\u201d\u3001\u201c\u5927\u5065\u5eb7\u201d\u53ef\u83b7\u53d6\u4e13\u9879\u8be6\u60c5\u653f\u7b56\uff0c\u4ee5\u4e0b\u4e3a\u300a\u5173\u4e8e\u53d1\u5c55\u58ee\u5927\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u96c6\u7fa4\u548c\u57f9\u80b2\u53d1\u5c55\u672a\u6765\u4ea7\u4e1a\u7684\u610f\u89c1\u300b\u539f\u6587\u3002<\/div>\n\n
\n
\"RmFicvQBAkgC1GU3z4lX0IM8ZNR2KjJ5EkIDAHeLtZ8dibtEFqpeQqNTkjz2ZCUibtkIvicEia3dZFE0SJqHLbABtLw\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u300a\u5173\u4e8e\u53d1\u5c55\u58ee\u5927\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u96c6\u7fa4\u548c\u57f9\u80b2\u53d1\u5c55\u672a\u6765\u4ea7\u4e1a\u7684\u610f\u89c1\u300b\uff08\u6765\u6e90\/\u6df1\u5733\u5e02\u4eba\u6c11\u653f\u5e9c\uff09<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/fgw.sz.gov.cn\/<\/div>\n
\u5b8f\u89c2\u73af\u5883<\/div>\n
\u2756\u00a0\u62d3\u65b0\u751f\u7269\u5b9e\u4f53\u7624CAR-T\u7ec6\u80de\u7597\u6cd5\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u83b7CDE\u53d7\u7406<\/div>\n
2022\u5e746\u67089\u65e5\uff0c\u798f\u5dde\u62d3\u65b0\u5929\u6210\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8(\u7b80\u79f0\u201c\u62d3\u65b0\u751f\u7269\u201d) TX103\u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de(CAR-T)\u6ce8\u5c04\u6db2\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u83b7CDE\u53d7\u7406\u3002TX103CAR-T\u662f\u4e00\u6b3e\u9776\u5411 TX103\u8de8\u819c\u86cb\u767d\u7684\u81ea\u4f53CAR-T\u7ec6\u80de\u7597\u6cd5\uff0c\u5728\u6d88\u5316\u9053\u80bf\u7624\uff0c\u8111\u80bf\u7624\u7b49\u591a\u79cd\u5b9e\u4f53\u7624\u4e2d\u9ad8\u8868\u8fbe\uff0c\u5728\u80bf\u7624\u5fae\u73af\u5883\u4e2d\u7684\u5176\u4ed6\u6210\u5206\u4e2d\u4e5f\u9ad8\u8868\u8fbe\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cde.org.cn\/main\/xxgk\/listpage\/9f9c74c73e0f8f56a8bfbc646055026d<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u56fd\u5bb6\u7ea7\u8f6c\u57fa\u56e0\u5927\u8c46\u7389\u7c73\u54c1\u79cd\u5ba1\u5b9a\u6807\u51c6\u53d1\u5e03<\/div>\n
2022\u5e746\u67088\u65e5\uff0c\u56fd\u5bb6\u519c\u4f5c\u7269\u54c1\u79cd\u5ba1\u5b9a\u59d4\u5458\u4f1a\u4e3a\u843d\u5b9e\u515a\u4e2d\u592e\u3001\u56fd\u52a1\u9662\u5173\u4e8e\u6709\u5e8f\u63a8\u8fdb\u751f\u7269\u80b2\u79cd\u4ea7\u4e1a\u5316\u5e94\u7528\u7684\u51b3\u7b56\u90e8\u7f72\uff0c\u6839\u636e\u300a\u4e2d\u534e\u4eba\u6c11\u5171\u548c\u56fd\u79cd\u5b50\u6cd5\u300b\u300a\u4e3b\u8981\u519c\u4f5c\u7269\u54c1\u79cd\u5ba1\u5b9a\u529e\u6cd5\u300b\u6709\u5173\u89c4\u5b9a\uff0c\u5236\u5b9a\u5e76\u5370\u53d1\u4e86\u300a\u56fd\u5bb6\u7ea7\u8f6c\u57fa\u56e0\u5927\u8c46\u54c1\u79cd\u5ba1\u5b9a\u6807\u51c6\uff08\u8bd5\u884c\uff09\u300b\u548c\u300a\u56fd\u5bb6\u7ea7\u8f6c\u57fa\u56e0\u7389\u7c73\u54c1\u79cd\u5ba1\u5b9a\u6807\u51c6\uff08\u8bd5\u884c\uff09\u300b\uff0c\u4e8e\u5370\u53d1\u4e4b\u65e5\u8d77\u5b9e\u65bd\u3002<\/div>\n\n
\n
\"RmFicvQBAkgC1GU3z4lX0IM8ZNR2KjJ5EiavrLA02AXIxssYc7CI8FJmejrR8gmuEWicYE1R1S65N4NpdribH4GicvQ\"\/<\/figure><\/div>\n\n
\n
\"RmFicvQBAkgC1GU3z4lX0IM8ZNR2KjJ5EKGXJOjA2b3IkzKhcFHpdU1xyYDp0aq3Lm97oXXbTkksCrkmEI1GNTw\"\/<\/figure><\/div>\n\n
\n
\"RmFicvQBAkgC1GU3z4lX0IM8ZNR2KjJ5EvXVjiaYIkkpsuicHqbkZuUetqOhnI2OZrxAIIG7k7g16hercAuDRJ0Fg\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u300a\u56fd\u5bb6\u7ea7\u8f6c\u57fa\u56e0\u5927\u8c46\u54c1\u79cd\u5ba1\u5b9a\u6807\u51c6\uff08\u8bd5\u884c\uff09\u300b\u548c\u300a\u56fd\u5bb6\u7ea7\u8f6c\u57fa\u56e0\u7389\u7c73\u54c1\u79cd\u5ba1\u5b9a\u6807\u51c6\uff08\u8bd5\u884c\uff09\u300b\uff08\u6765\u6e90\/\u56fd\u5bb6\u519c\u4f5c\u7269\u54c1\u79cd\u5ba1\u5b9a\u59d4\u5458\u4f1a\uff09<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.moa.gov.cn\/xw\/bmdt\/202206\/t20220609_6401985.htm<\/div>\n<\/p>\n
\u2756\u00a0CDE\u53d1\u5e03\u300a\u4e2d\u56fd\u65b0\u836f\u6ce8\u518c\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u5c55\u5e74\u5ea6\u62a5\u544a\uff082021\u5e74\uff09\u300b<\/div>\n
2022\u5e746\u67087\u65e5\uff0cCDE\u53d1\u5e03\u4e86\u300a\u4e2d\u56fd\u65b0\u836f\u6ce8\u518c\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u5c55\u5e74\u5ea6\u62a5\u544a(2021\u5e74)\u300b\uff0c\u62a5\u544a\u4e3b\u8981\u6839\u636e2021\u5e74\u5ea6\u767b\u8bb0\u7684\u836f\u7269\u4e34\u5e8a\u8bd5\u9a8c\u4fe1\u606f\uff0c\u4ece\u836f\u7269\u7c7b\u578b\u3001\u54c1\u79cd\u53ca\u9776\u70b9\u7279\u5f81\u3001\u9002\u5e94\u75c7\u7b49\u89d2\u5ea6\u5bf9\u4e34\u5e8a\u8bd5\u9a8c\u7684\u603b\u4f53\u8d8b\u52bf\u53d8\u5316\u3001\u4e3b\u8981\u7279\u70b9\u3001\u7a81\u51fa\u95ee\u9898\u7b49\u8fdb\u884c\u6c47\u603b\u5206\u6790\uff0c\u540c\u65f6\u5bf9\u6bd4\u8fd1\u4e09\u5e74\u4e34\u5e8a\u8bd5\u9a8c\u767b\u8bb0\u6570\u636e\uff0c\u5bf9\u8fd1\u5e74\u6765\u7684\u8d8b\u52bf\u7279\u5f81\u8fdb\u884c\u603b\u7ed3\u5206\u6790\u3002\u4ee5\u4e0b\u4e3a\u6458\u8981\u5185\u5bb9\uff0c\u6d4f\u89c8\u5b8c\u6574\u6587\u4ef6\uff0c\u53ef\u5728\u516c\u4f17\u53f7\u8f93\u5165\u5173\u952e\u8bcd\u201c\u65b0\u836f\u6ce8\u518c\u201d\u3002<\/div>\n
<\/div>\n\n
\n
\"RmFicvQBAkgB9LOFOeWssl2Q729L7LQibZAOTLXRzBOpYYmTIQfZEQ9fjQCnLrBqtxfrHUdaJLcvgmexYb9rltvA\"\/<\/figure><\/div>\n\n
\n
\"RmFicvQBAkgB9LOFOeWssl2Q729L7LQibZDPj9lSpiamXSfmMBmIlSX7lc1LyBiceoj7Lw7s9iayneDXpjdBm7v9J3A\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u300a\u4e2d\u56fd\u65b0\u836f\u6ce8\u518c\u4e34\u5e8a\u8bd5\u9a8c\u8fdb\u5c55\u5e74\u5ea6\u62a5\u544a\uff082021\u5e74\uff09\u300b\uff0c\uff08\u6765\u6e90\/CDE\u5b98\u7f51\uff09<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.cnpharm.com\/c\/2022-06-07\/827624.shtml<\/div>\n
\u2756\u00a0\u767e\u66a8\u57fa\u56e0CAR-T\u6ce8\u5c04\u6db2\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u83b7CDE\u53d7\u7406\uff0c\u7528\u4e8e\u6cbb\u7597\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5<\/div>\n
2022\u5e746\u67087\u65e5\uff0c\u767e\u66a8\u57fa\u56e0\u81ea\u4f53\u6297CLL-1 \u5d4c\u5408\u6297\u539f\u53d7\u4f53T\u7ec6\u80de\uff08CAR-T\uff09\u6ce8\u5c04\u6db2\u4e34\u5e8a\u8bd5\u9a8c\u7533\u8bf7\u5df2\u83b7CDE\u53d7\u7406\uff0c\u7528\u4e8e\u6cbb\u7597\u6025\u6027\u9ad3\u7cfb\u767d\u8840\u75c5\uff08AML\uff09\u3002\u8be5\u65b0\u836f\u4e0a\u5e02\u540e\u5c06\u63d0\u9ad8CAR-T\u836f\u7269\u7684\u53ef\u53ca\u6027\uff0c\u5bf9\u6253\u7834\u56fd\u5185AML\u60a3\u8005\u65e0\u7279\u6548\u836f\uff0c\u56fd\u5916\u8fdb\u53e3\u836f\u3001\u9ad8\u4ef7\u836f\u5784\u65ad\u56fd\u5185\u5e02\u573a\u7684\u683c\u5c40\u5177\u6709\u91cd\u8981\u610f\u4e49\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.gzbiogene.com\/index.php\/News\/detail\/id\/129<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u9999\u96eaTCR-T\u4ea7\u54c1I\u671f\u4e34\u5e8a\u6570\u636e\u4eae\u76f8ASCO\uff0c\u5ba2\u89c2\u7f13\u89e3\u738741.7%<\/div>\n
2022\u5e746\u67085\u65e5\uff0c\u4e2d\u5c71\u5927\u5b66\u80bf\u7624\u9632\u6cbb\u4e2d\u5fc3\u7684\u5f20\u661f\u6559\u6388\u57282022\u5e74\u7f8e\u56fd\u4e34\u5e8a\u80bf\u7624\u5b66\u4f1a(ASCO)\u5e74\u4f1a\u4e0a\uff0c\u5bf9TAEST16001\u7684I\u671f\u4e34\u5e8a\u7814\u7a76\u7ed3\u679c\u8fdb\u884c\u4e86\u6458\u8981\u53e3\u5934\u6c47\u62a5\u3002TAEST16001\u662f\u9999\u96ea\u5236\u836f\u65d7\u4e0b\u9999\u96ea\u751f\u547d\u79d1\u5b66\u6280\u672f(\u5e7f\u4e1c)\u6709\u9650\u516c\u53f8\u81ea\u4e3b\u7814\u53d1\uff0c\u6211\u56fd\u9996\u4e2a\u83b7IND\u6279\u4ef6\u7684TCR-T\u514d\u75ab\u7ec6\u80de\u7597\u6cd5\uff0c\u5176I\u671f\u4e34\u5e8a\u7814\u7a76\u80bf\u762441.7%\u7684\u5ba2\u89c2\u7f13\u89e3\u7387\u83b7\u5168\u7403\u4e1a\u754c\u9ad8\u5ea6\u5173\u6ce8\u3002\uff08\u8be6\u60c5\u70b9\u51fb\uff09<\/a><\/div>\n
\u00a0<\/div>\n
\u6295\u878d\u8d44<\/div>\n
\u2756\u00a0\u56fd\u5185\u4e09\u5bb6\u57fa\u56e0\u4f01\u4e1a\u878d\u8d44\uff0c\u603b\u8ba1\u8d855\u4ebf\u5143\u4eba\u6c11\u5e01<\/div>\n\n
\n
\"RmFicvQBAkgB9LOFOeWssl2Q729L7LQibZnUDAr2UkZx9tcIhkLkMOTKza9ibIvqurRPae0ZYVqYpmUbQB9DMzfaA\"\/<\/figure><\/div>\n\n
\u56fe\uff1a\u56fd\u5185\u4e09\u5bb6\u57fa\u56e0\u4f01\u4e1a\u878d\u8d44\u60c5\u51b5\uff08\u6765\u6e90\/\u57fa\u56e0\u6167\u6574\u7406\uff09<\/div>\n
2022\u5e746\u67086\u65e5\u81f312\u65e5\uff0c\u56fd\u5185\u57fa\u56e0\u4f01\u4e1a\u53d1\u751f3\u8d77\u878d\u8d44\u4e8b\u4ef6\uff0c\u603b\u8ba1\u8d855\u4ebf\u5143\u4eba\u6c11\u5e01\u3002\u4e09\u5bb6\u4f01\u4e1a\u878d\u8d44\u8d5b\u9053\u4e0d\u540c\uff0c\u672c\u6b21\u878d\u8d44\u7684\u8d44\u91d1\uff0c\u5609\u68c0\u533b\u5b66\u5c06\u7528\u4e8e\u57fa\u56e0\u68c0\u6d4b\uff0c\u63a8\u52a8\u4e2d\u56fd\u51fa\u751f\u7f3a\u9677\u9632\u63a7\u4f53\u7cfb\u5efa\u8bbe\u3001\u9e4d\u8fdc\u751f\u7269\u5c06\u7528\u4e8e\u80bf\u7624\u65e9\u7b5b\u3001\u5148\u5eb7\u8fbe\u96c6\u56e2\u5219\u7528\u4e8e\u63a8\u8fdb\u7ec6\u80de\u836f\u7269\u5f00\u53d1\u3002\u4ee5\u4e0b\u4e3a\u4e09\u5bb6\u516c\u53f8\u7684\u4ecb\u7ecd\uff1a<\/div>\n
\u5609\u68c0\u533b\u5b66\u662f\u4e00\u5bb6\u7efc\u5408\u6027\u751f\u7269\u533b\u7597\u4f01\u4e1a\uff0c\u4e13\u6ce8\u4e8e\u4e34\u5e8a\u9057\u4f20\u4e13\u79d1\u670d\u52a1\u3001\u63d0\u4f9b\u4e13\u4e1a\u5316\u4e34\u5e8a\u9057\u4f20\u75c5\u8bca\u65ad\u548c\u9057\u4f20\u54a8\u8be2\u7efc\u5408\u89e3\u51b3\u65b9\u6848\uff0c\u81f4\u529b\u4e8e\u63a8\u52a8\u57fa\u56e0\u7ec4\u68c0\u6d4b\u6280\u672f\u5728\u4e34\u5e8a\u7684\u8f6c\u5316\u5e94\u7528\u3002\u672c\u6b21\u878d\u8d44\u5c06\u7528\u4e8e\u63a8\u52a8\u4e2d\u56fd\u51fa\u751f\u7f3a\u9677\u9632\u63a7\u4f53\u7cfb\u5efa\u8bbe\u3002<\/div>\n
\u00a0<\/div>\n
\u9e4d\u8fdc\u751f\u7269\u662f\u4e00\u5bb6\u4e13\u6ce8\u4e8e\u65b0\u4e00\u4ee3\u57fa\u56e0\u68c0\u6d4b\u548c\u5206\u5b50\u8bca\u65ad\u6280\u672f\u7684\u7814\u53d1\u548c\u4e34\u5e8a\u5e94\u7528\u7684\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u9ad8\u53d1\u80bf\u7624\u7684\u9884\u9632\u3001\u53d1\u751f\u548c\u53d1\u5c55\uff0c\u5f00\u53d1\u7cfb\u5217\u89e3\u51b3\u65b9\u6848\u2014\u2014\u6d89\u53ca\u98ce\u9669\u8bc4\u4f30\u3001\u65e9\u671f\u7b5b\u67e5\u3001\u7528\u836f\u6307\u5bfc\u53ca\u672f\u540e\u76d1\u6d4b\u7684\u5168\u5468\u671f\u670d\u52a1\uff0c\u5c24\u5176\u662f\u57fa\u4e8e\u4e13\u5229\u7532\u57fa\u5316\u68c0\u6d4b\u5e73\u53f0\u7684\u80bf\u7624\u65e0\u521b\u65e9\u671f\u7b5b\u67e5\u548c\u8bca\u65ad\u6280\u672f\u7684\u5f00\u53d1\u548c\u5e94\u7528\u3002<\/div>\n
\u5b98\u7f51>>http:\/\/www.singlera.com.cn\/<\/div>\n
\u00a0<\/div>\n
\u5148\u5eb7\u8fbe\u751f\u7269\u662f\u4e00\u5bb6\u7ec6\u80de\u6cbb\u7597\u670d\u52a1\u5546\uff0c\u91cd\u70b9\u7814\u53d1\u5e72\u7ec6\u80de\u6cbb\u7597\u6280\u672f\u3001\u514d\u75ab\u7ec6\u80de\u6cbb\u7597\u6280\u672f\u548c\u57fa\u56e0\u6cbb\u7597\u6280\u672f\uff0c\u642d\u5efa\u7ec6\u80de\u5b58\u50a8\u3001\u7ec6\u80de\u6cbb\u7597\u6280\u672f\u3001\u7ec6\u80de\u6297\u8870\u6280\u672f\u3001\u7ec6\u80de\u8d28\u91cf\u68c0\u6d4b\u56db\u5927\u5e73\u53f0\uff0c\u4e3a\u5065\u5eb7\u3001\u4e9a\u5065\u5eb7\u3001\u75c5\u4eba\u7b49\u4eba\u7fa4\u5b9a\u5236\u5404\u79cd\u6297\u8870\u65b9\u6848\u548c\u6162\u6027\u75c5\u7ba1\u7406\u65b9\u6848\u3002\u5148\u5eb7\u8fbe\u96c6\u56e2\u662f\u4ee5\u5e7f\u4e1c\u5148\u5eb7\u8fbe\u4e3a\u6bcd\u516c\u53f8\u7ec4\u5efa\u7684\u4f01\u4e1a\u96c6\u56e2\uff0c\u4ee5\u7ec6\u80de\u6cbb\u7597\u4e3a\u6838\u5fc3\u4ea7\u4e1a\u3002<\/div>\n
\u5b98\u7f51>>http:\/\/www.xkdbio.com\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Tessa Therapeutics\u5b8c\u62101.26\u4ebf\u7f8e\u5143\u7684A\u8f6e\u878d\u8d44<\/div>\n
2022\u5e746\u670810\u65e5\uff0cTessa Therapeutics\u516c\u53f8\u5ba3\u5e03\u5b8c\u62101.26\u4ebf\u7f8e\u5143\u7684A\u8f6e\u878d\u8d44\uff0c\u83b7\u5f97\u8d44\u91d1\u5c06\u7528\u4e8e\u63a8\u52a8\u8be5\u516c\u53f8\u7684\u5728\u7814\u81ea\u4f53CAR-T\u7597\u6cd5TT11\u548c\u540c\u79cd\u5f02\u4f53\u7ec6\u80de\u7597\u6cd5TT11X\u7684\u4e34\u5e8a\u5f00\u53d1\u3002Tessa\u662f\u4e00\u5bb6\u4e34\u5e8a\u671f\u751f\u7269\u6280\u672f\u516c\u53f8\uff0c\u81f4\u529b\u4e8e\u5f00\u53d1\u6cbb\u7597\u8840\u6db2\u764c\u75c7\u548c\u5b9e\u4f53\u7624\u7684\u65b0\u4e00\u4ee3\u7ec6\u80de\u7597\u6cd5\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.tessacell.com\/<\/div>\n
\u00a0<\/div>\n
\u4f1a\u8bae\u63a8\u8350<\/div>\n
\u2756\u00a0\u7b2c\u4e94\u5c4a\u4e2d\u56fd\u7814\u7a76\u578b\u533b\u9662\u5b66\u4f1a\u513f\u7ae5\u80bf\u7624\u4e13\u4e1a\u59d4\u5458\u4f1a\u5b66\u672f\u4f1a\u8bae\uff0c2022\u5e748\u670820\u65e5\u81f321\u65e5\uff0c\u90d1\u5dde<\/div>\n
\u7b2c\u4e94\u5c4a\u4e2d\u56fd\u7814\u7a76\u578b\u533b\u9662\u5b66\u4f1a\u513f\u7ae5\u80bf\u7624\u4e13\u4e1a\u59d4\u5458\u4f1a\u5b66\u672f\u4f1a\u8bae\u5c06\u4e8e2022\u5e748\u670820\u65e5\u81f321\u65e5\u4e8e\u6cb3\u5357\u90d1\u5dde\u4e3e\u884c\uff0c\u5206\u4e3a\u7ebf\u4e0b\u4f1a\u573a\u4e0e\u7ebf\u4e0a\u4f1a\u573a\u3002\u672c\u6b21\u4f1a\u8bae\u7684\u4e3b\u529e\u662f\u4e2d\u56fd\u7814\u7a76\u578b\u533b\u9662\u5b66\u4f1a\uff0c\u4f1a\u8bae\u65e8\u5728\u63d0\u9ad8\u6211\u56fd\u513f\u7ae5\u80bf\u7624\u7684\u9632\u6cbb\u548c\u7814\u7a76\u6c34\u5e73\uff0c\u63a8\u8fdb\u513f\u7ae5\u80bf\u7624\u89c4\u8303\u5316\u8bca\u65ad\u548c\u6cbb\u7597\uff0c\u6539\u5584\u513f\u7ae5\u80bf\u7624\u7684\u6cbb\u7597\u6548\u679c\u548c\u8d28\u91cf\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/tac.castscs.org.cn\/meeting-detail?id=1353<\/div>\n
\u00a0<\/div>\n
\u2756\u00a02023\u5e74\u7f8e\u56fd\u533b\u5b66\u9057\u4f20\u5b66\u4e0e\u57fa\u56e0\u7ec4\u5b66\u5b66\u4f1a\u5e74\u4f1a\uff0c2023\u5e743\u670814\u65e5\u81f318\u65e5\uff0c\u7f8e\u56fd\u00b7\u76d0\u6e56\u57ce<\/div>\n
2023\u5e74\u7f8e\u56fd\u533b\u5b66\u9057\u4f20\u5b66\u4e0e\u57fa\u56e0\u7ec4\u5b66\u5b66\u4f1a\u5e74\u4f1a\u5c06\u4e8e2023\u5e743\u670814\u65e5\u81f318\u65e5\u4e8e\u7f8e\u56fd\u76d0\u6e56\u57ce\u4e3e\u884c\uff0cACMG\u5e74\u5ea6\u4e34\u5e8a\u9057\u4f20\u5b66\u4f1a\u8bae\u662f\u533b\u5b66\u548c\u4e34\u5e8a\u9057\u4f20\u5b66\u548c\u57fa\u56e0\u7ec4\u5b66\u9886\u57df\u4e13\u4e1a\u4eba\u58eb\u7684\u9996\u8981\u6559\u80b2\u6d3b\u52a8\u3002\u4f1a\u8bae\u63d0\u4f9b\u4e86\u4f53\u9a8c\u533b\u5b66\u9057\u4f20\u5b66\u548c\u57fa\u56e0\u7ec4\u5b66\u5728\u533b\u5b66\u5b9e\u8df5\u4e2d\u7684\u5173\u952e\u4f5c\u7528\u53ca\u5e94\u7528\u4e34\u5e8a\u4e0e\u5b9e\u9a8c\u5ba4\u7684\u673a\u4f1a\uff0c\u4fc3\u8fdb\u8bca\u65ad\u3001\u6cbb\u7597\u548c\u9884\u9632\u9057\u4f20\u75be\u75c5\u65b9\u6cd5\u7684\u53d1\u5c55\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.globalconfs.com\/meeting\/27112.html<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u53d1\u5c55<\/div>\n
\u2756\u00a0FDA\u6279\u51c6\u9996\u4e2aROS1\u57fa\u56e0\u878d\u5408\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u6216NTRK \u57fa\u56e0\u878d\u5408\u5b9e\u4f53\u4f34\u968f\u8bca\u65ad\u4ea7\u54c1<\/div>\n
2022\u5e746\u67089\u65e5\uff0c\u7f57\u6c0f\u5b50\u516c\u53f8Foundation Medicine\u5ba3\u5e03\uff0c\u5176\u4f34\u968f\u8bca\u65ad\u4ea7\u54c1FoundationOne\u5df2\u83b7\u6279FDA\uff0c\u53ef\u7528\u4e8e\u8bc6\u522b ROS1 \u878d\u5408\u9633\u6027\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u60a3\u8005\u6216 NTRK \u878d\u5408\u9633\u6027\u5b9e\u4f53\u7624\u60a3\u8005\uff0c\u8fd9\u4e9b\u60a3\u8005\u53ef\u80fd\u9002\u5408\u4f7f\u7528\u7f57\u6c0f Rozlytrek\uff08entrectinib\uff09\u6cbb\u7597\u3002\u8fd9\u662f\u7b2c\u4e00\u4e2a\u4e5f\u662f\u552f\u4e00\u4e00\u4e2a\u83b7\u5f97 FDA \u6279\u51c6\u7684\u7528\u4e8e\u8fd9\u4e00\u9002\u5e94\u75c7\u7684\u4f34\u968f\u8bca\u65ad\u4ea7\u54c1\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.foundationmedicine.com\/press-releases\/3fe223c4-f8ae-4c35-b138-47ad284f6452<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u534e\u5927\u667a\u9020\u4e0e\u65b0\u52a0\u5761\u751f\u7269\u6280\u672f\u516c\u53f8MiRXES\u5408\u4f5c\uff0c\u6784\u5efa\u65f6\u7a7a\u7ec4\u5b66\u5e73\u53f0<\/div>\n
2022\u5e746\u67087\u65e5\uff0c\u534e\u5927\u667a\u9020\u4e0e\u65b0\u52a0\u5761\u751f\u7269\u6280\u672f\u516c\u53f8MiRXES\u8fbe\u6210\u5408\u4f5c\uff0c\u6784\u5efa\u9ad8\u901a\u91cf\u3001\u9ad8\u5206\u8fa8\u7387\u7684\u65f6\u7a7a\u7ec4\u5b66\u5e73\u53f0\u3002MiRXES\u5c06\u51ed\u501f\u5176RNA\u7aef\u5230\u7aef\u8f6c\u5316\u7814\u7a76\u80fd\u529b\u548c\u5206\u5b50\u8bca\u65ad\u5f00\u53d1\u80fd\u529b\uff0c\u7ed3\u5408\u6df1\u5733\u534e\u5927\u751f\u547d\u79d1\u5b66\u7814\u7a76\u9662\u81ea\u4e3b\u7814\u53d1\u7684\u65f6\u7a7a\u7ec4\u5b66Stereo-seq\u6280\u672f\uff0c\u57fa\u4e8e\u534e\u5927\u667a\u9020\u9886\u5148\u7684DNBSEQ-T10\u00d74RS\u6d4b\u5e8f\u5e73\u53f0\uff0c\u6784\u5efa\u65f6\u7a7a\u7ec4\u5b66\u5e73\u53f0\u3002\u8fd9\u4e5f\u5c06\u6210\u4e3a\u4e2d\u56fd\u4ee5\u5916\u4e9a\u592a\u5730\u533a\u7684\u9996\u4e2a\u6b64\u7c7b\u5e73\u53f0\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/mirxes.com\/mirxes-bgi-research-mgi-strategic-partnership\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Editas\u4e0eImmatic\u5408\u4f5c\u548c\u8bb8\u53ef\u534f\u8bae\uff0c\u57fa\u4e8e\u57fa\u56e0\u7f16\u8f91\u6280\u672f\u6cbb\u7597\u764c\u75c7<\/div>\n
2022\u5e746\u67087\u65e5\uff0cEditas Medicine\u4e0eImmatic\u5ba3\u5e03\u8fbe\u6210\u5408\u4f5c\uff0c\u5c06gamma-delta\uff08\u03b3\u03b4\uff09T\u7ec6\u80de\u8fc7\u7ee7\u7ec6\u80de\u7597\u6cd5\u548c\u57fa\u56e0\u7f16\u8f91\u76f8\u7ed3\u5408\uff0c\u4ee5\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597\u764c\u75c7\u7684\u836f\u7269\u3002\u4f5c\u4e3a\u8bb8\u53ef\u534f\u8bae\u7684\u4e00\u90e8\u5206\uff0cImmatics\u5c06\u83b7\u5f97Editas CRISPR\u6280\u672f\u548c\u77e5\u8bc6\u4ea7\u6743\u7684\u975e\u72ec\u5bb6\u6743\u5229\u3002immatics\u662f\u4e00\u5bb6\u751f\u7269\u5236\u836f\u516c\u53f8\uff0c\u4e13\u6ce8\u4e8e\u5f00\u53d1\u7528\u4e8e\u764c\u75c7\u6cbb\u7597\u7684\u514d\u75ab\u6cbb\u7597\u7269\u8d28\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/ir.editasmedicine.com\/news-releases\/news-release-details\/immatics-and-editas-medicine-enter-strategic-research<\/div>\n
\u00a0<\/div>\n
\u79d1\u7814\u5e94\u7528<\/div>\n
\u2756\u00a0Cell\u00a0\uff1a\u56db\u56fd\u79d1\u5b66\u5bb6\u53d1\u73b0\u5fc3\u8840\u7ba1\u75be\u75c5\u76f8\u5173\u7684LDLR\u00a0\u57fa\u56e0\u53d8\u4f53<\/div>\n
2022\u5e746\u67089\u65e5\uff0c\u4e39\u9ea6\u3001\u683c\u9675\u5170\u3001\u7f8e\u56fd\u548c\u632a\u5a01\u7684\u7814\u7a76\u4eba\u5458\u5728Cell \u520a\u6587\uff0c\u81ea1990\u5e74\u4ee3\u540e\u671f\u81f32010\u5e74\u95f4\uff0c\u4ed6\u4eec\u6c47\u603b\u4e86\u8fd15100\u540d\u683c\u9675\u5170\u4eba\u7684\u767b\u8bb0\u6570\u636e\uff0c\u53d1\u73b0\u4e86\u4e00\u79cd\u5e38\u89c1\u7684\u5317\u6781\u7279\u5f02\u6027LDLR\u00a0p.G137S \u57fa\u56e0\u53d8\u4f53\u3002\u7ea630%\u7684\u683c\u9675\u5170\u4eba\u643a\u5e26\u81f3\u5c11\u4e00\u4efd\u8be5\u57fa\u56e0\u53d8\u4f53\uff0c\u8d85\u8fc7\u56db\u5206\u4e4b\u4e00\u7684\u6742\u5408 p.G137S \u643a\u5e26\u8005\u8868\u73b0\u51fa\u9ad8LDL\u80c6\u56fa\u9187\u6c34\u5e73\uff0c\u8fd9\u8868\u660e\u8be5\u53d8\u4f53\u53ef\u80fd\u5bf9\u6574\u4e2a\u4eba\u7fa4\u7684\u8102\u8d28\u548c\u5fc3\u8840\u7ba1\u5f71\u54cd\u5f88\u5927\u3002\u7814\u7a76\u8005\u8ba4\u4e3a\uff0cp.G137S \u57fa\u56e0\u53d8\u4f53\u7b5b\u67e5\u6216\u6709\u52a9\u4e8e\u65e9\u671f\u8bc6\u522b\u5fc3\u8840\u7ba1\u75be\u75c5\u98ce\u9669\u589e\u52a0\u7684\u4e2a\u4f53\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cell.com\/hgg-advances\/fulltext\/S2666-2477(22)00034-3<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Cell\uff1a\u57fa\u4e8e\u65b0\u7684CRISPR\u7684\u56fe\u8c31\u53ef\u8f7b\u677e\u67e5\u627e\u57fa\u56e0\u578b-\u8868\u578b\u7684\u5173\u7cfb<\/div>\n
2022\u5e746\u67089\u65e5\uff0c\u7f8e\u56fd\u52a0\u5dde\u5927\u5b66Joseph M. Replogle\u7814\u7a76\u56e2\u961f\u53ca\u5408\u4f5c\u8005\u5728Cell\u00a0\u520a\u6587\uff0c\u5229\u7528\u8d85250\u4e07\u4e2a\u4eba\u7c7b\u7ec6\u80de\u4e2d\u6267\u884c\u57fa\u56e0\u7ec4\u89c4\u6a21\u7684Perturb-seq\uff0c\u9488\u5bf9\u6240\u6709\u8868\u8fbe\u7684\u57fa\u56e0\u8fdb\u884cCRISPR\u5e72\u6270 (CRISPRi)\uff0c\u4f7f\u7528\u8f6c\u5f55\u8868\u578b\u6765\u9884\u6d4b\u7279\u5f81\u4e0d\u660e\u786e\u7684\u57fa\u56e0\u529f\u80fd\uff0c\u63ed\u793a\u4e86\u6838\u7cd6\u4f53\u751f\u7269\u5408\u6210\uff08\u5305\u62ecCCDC86\u3001ZNF236\u548cSPATA5L1\uff09\u3001\u8f6c\u5f55\uff08C7orf26\uff09\u548c\u7ebf\u7c92\u4f53\u547c\u5438\uff08TMEM242\uff09\u7684\u65b0\u8c03\u8282\u56e0\u5b50\uff09\u3002\u9664\u6b64\u4e4b\u5916\uff0c\u57fa\u56e0\u578b-\u8868\u578b\u56fe\u8fd8\u5c55\u793a\u4e86\u57fa\u56e0\u548c\u7ec6\u80de\u529f\u80fd\u7684\u591a\u7ef4\u753b\u50cf\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(22)00597-9#%20<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Scientific Reports\u00a0:\u00a0\u65e5\u672c\u9ebb\u5e03\u5927\u5b66\u53d1\u73b0\u72ac\u7c7b\u4e0e\u4eba\u4e3a\u53cb\u7684\u9057\u4f20\u7ebf\u7d22<\/div>\n
2022\u5e746\u67089\u65e5\uff0c\u65e5\u672c\u9ebb\u5e03\u5927\u5b66\u517d\u533b\u5b66\u90e8\u79d1\u5b66\u5bb6\u5728Scientific Reports\u00a0\u520a\u6587\uff0c\u9ed1\u7d20\u76ae\u8d28\u7d20\u53d7\u4f53-2\uff08MC2R\uff09\u57fa\u56e0\u53ef\u80fd\u5728\u72ac\u7c7b\u7684\u9a6f\u5316\u4e2d\u53d1\u6325\u4e86\u4f5c\u7528\uff0c\u8be5\u57fa\u56e0\u6216\u8bb8\u8ba9\u72ac\u7c7b\u5728\u4eba\u7c7b\u8eab\u8fb9\u65f6\u538b\u529b\u6c34\u5e73\u66f4\u4f4e\uff0c\u540c\u65f6\u4e5f\u8ba9\u72ac\u7c7b\u53d1\u5c55\u51fa\u80fd\u4e0e\u4eba\u7c7b\u4e92\u52a8\u7684\u793e\u4f1a\u8ba4\u77e5\u6280\u80fd\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41598-022-11130-x<\/div>\n
\u7f16\u8f91 | \u5f20\u742a<\/div>\n
\u6821\u5bf9 | Shelly<\/div>\n
\u00a0<\/div>\n
\u62d3\u5c55\u9605\u8bfb<\/div>\n
\u5386\u5e74\u84dd\u76ae\u4e66\u6c47\u603b\uff0c\u5efa\u8bae\u6536\u85cf<\/div>\n
\u4e3a\u4ec0\u4e48\u8bf4NGS\u6280\u672f\u6709\u671b\u6210\u4e3a\u4e34\u5e8a\u5e38\u89c4\u5316\u68c0\u6d4b\u624b\u6bb5\uff1f<\/div>\n
\u60a8\u6709\u4e00\u4efd\u57fa\u56e0\u79d1\u666e\u7d20\u6750\uff0c\u8bf7\u67e5\u6536\uff01<\/div>\n
\u3010\u58f0\u660e\u3011\u4e3a\u4e86\u63a8\u52a8\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u79d1\u6280\u63a8\u5e7f\u3001\u4ea7\u4e1a\u53d1\u5c55\u53ca\u653f\u4ea7\u5b66\u7814\u7528\u8fde\u63a5\uff0c\u57fa\u56e0\u6167\u79c9\u6301\u4e13\u4e1a\u3001\u8d4b\u80fd\u3001\u4e2d\u7acb\u7684\u7acb\u573a\u6536\u96c6\u3001\u5206\u6790\u53ca\u53d1\u5e03\u76f8\u5173\u4fe1\u606f\u3002\u4f46\u7531\u4e8e\u65f6\u6548\u6027\u53ca\u884c\u4e1a\u7279\u6b8a\u6027\uff0c\u6240\u520a\u767b\u5185\u5bb9\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u672a\u7ecf\u8bf4\u660e\u4e0d\u4f5c\u4e3a\u51b3\u7b56\u4f9d\u636e\uff1b\u672c\u6587\u76f8\u5173\u4fe1\u606f\u4e0d\u4ee3\u8868\u57fa\u56e0\u6167\u7684\u89c2\u70b9\uff1b\u57fa\u56e0\u6167\u5e73\u53f0\u520a\u767b\u7684\u539f\u521b\u5185\u5bb9\u7684\u77e5\u8bc6\u4ea7\u6743\u4e3a\u201c\u57fa\u56e0\u6167\u201d\u5546\u6807\u62e5\u6709\u8005\u53ca\u76f8\u5173\u6743\u5229\u4eba\u6240\u6709\uff1b\u6b22\u8fce\u8f6c\u8f7d\uff0c\u8f6c\u8f7d\u8bf7\u7533\u8bf7\u5e76\u6ce8\u660e\u6765\u6e90\u3002\u6b22\u8fce\u4e2a\u4eba\u53ca\u673a\u6784\u6295\u7a3f\u53ca\u5408\u4f5c\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u5173\u4e8e\u57fa\u56e0\u6167\u00a0<\/div>\n
\u57fa\u56e0\u6167\u4e13\u6ce8\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u77e5\u8bc6\u670d\u52a1\u3002\u521b\u59cb\u56e2\u961f\u6df1\u8015\u884c\u4e1a\u4e00\u7ebf\u5341\u4f59\u5e74\uff0c\u79c9\u6301\u201c\u4f7f\u8fde\u63a5\u4ea7\u751f\u4ef7\u503c\uff0c\u7528\u6570\u636e\u770b\u89c1\u672a\u6765\u201d\u7684\u7406\u5ff5\uff0c\u57fa\u4e8e\u4ea7\u4e1a\u667a\u5e93\u548c\u4e13\u4e1a\u5185\u5bb9\uff0c\u63d0\u4f9b\u4ea7\u4e1a\u89c4\u5212\u3001\u884c\u7814\u54a8\u8be2\u3001\u79d1\u6280\u63a8\u5e7f\u7b49\u670d\u52a1\u3002\u8fde\u7eed\u4e94\u5e74\u53d1\u5e03\u884c\u4e1a\u84dd\u76ae\u4e66\uff0c\u88ab\u56fd\u5bb6\u53ca\u7701\u5e02\u7ea7\u4ea7\u4e1a\u62a5\u544a\u6536\u5f55\uff0c\u7ec4\u7ec7\u591a\u5bb6\u5355\u4f4d\u53d1\u5e03\u884c\u4e1a\u5171\u8bc6\u548c\u56e2\u6807\uff0c\u63a8\u52a8\u751f\u547d\u79d1\u6280\u666e\u60e0\u548c\u4ea7\u4e1a\u878d\u5408\u53d1\u5c55\u3002<\/div>\n
\u2606\u00a0\u56fd\u53d1\u6539\u300a\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b\u767d\u76ae\u4e66\u6267\u7b14<\/div>\n
\u2606\u00a0\u8fde\u7eed\u4e94\u5e74\u53d1\u5e03\u57fa\u56e0\u884c\u4e1a\u84dd\u76ae\u4e66<\/div>\n
\u2606\u00a0\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u80bf\u7624\u6807\u5fd7\u4e13\u4e1a\u59d4\u5458\u4f1a\u6218\u7565\u5408\u4f5c\u5355\u4f4d<\/div>\n
\u2606\u00a0\u4e2d\u56fd\u9057\u4f20\u5b66\u4f1a\u751f\u7269\u4ea7\u4e1a\u4fc3\u8fdb\u59d4\u5458\u4f1a\u59d4\u5458<\/div>\n
\u2606\u00a0\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5e94\u7528\u5b66\u4f1a\u653f\u7b56\u7814\u7a76\u5e94\u7528\u5206\u4f1a\u5e38\u59d4<\/div>\n
\u2606\u00a0\u6df1\u5733\u5e02\u5065\u5eb7\u4ea7\u4e1a\u53d1\u5c55\u4fc3\u8fdb\u4f1a\u526f\u4f1a\u957f\u5355\u4f4d<\/div>\n
\u2606\u00a0\u53c2\u4e0e\u7ec4\u7ec7\u673a\u6784\u53d1\u5e03\u591a\u9879\u884c\u4e1a\u5171\u8bc6\u548c\u56e2\u4f53\u6807\u51c6<\/div>\n
\u2606\u00a0\u7ec4\u7ec7\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\uff08\u7b79\uff09\u9996\u5c4a\u3001\u7b2c\u4e8c\u5c4a\u4f1a\u8bae<\/div>\n
\u2606\u00a0\u4e3b\u529e\u6570\u5b57\u5065\u5eb7\u79c1\u8463\u4f1a\u3001\u5927\u6e7e\u533a\u751f\u547d\u5065\u5eb7\u521b\u65b0\u8bba\u575b<\/div>\n
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