{"id":8688,"date":"2022-08-26T12:00:00","date_gmt":"2022-08-26T04:00:00","guid":{"rendered":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/08\/26\/555548\/"},"modified":"2026-04-01T10:31:26","modified_gmt":"2026-04-01T02:31:26","slug":"555548","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2022\/08\/26\/555548\/","title":{"rendered":"\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5\uff08201\u671f\uff09"},"content":{"rendered":"

<\/p>\n

\u00a0<\/div>\n
\u4e00\u5468\u70ed\u70b9<\/div>\n
1.NMPA\u6279\u51c6\uff1a\u9996\u6b3e\u4e2d\u7f8e\u6b27\u540c\u65f6\u83b7\u6279\u7684\u591a\u764c\u79cdNGS\u901a\u7528\u4f34\u968f\u8bca\u65ad\u8bd5\u5242\u76d2\u4e0a\u5e02<\/div>\n
2.FDA\u6279\u51c6\uff1a\u7528\u4e8e\u6cbb\u7597\u03b2-\u5730\u4e2d\u6d77\u8d2b\u8840\u7684\u57fa\u56e0\u7597\u6cd5<\/div>\n
3.Illumina\uff1a\u4e0a\u6d77\u9996\u4e2a\u57fa\u56e0\u6d4b\u5e8f\u751f\u4ea7\u5236\u9020\u57fa\u5730\u542f\u7528<\/div>\n
4.\u79d1\u5b66\u5bb6\u5408\u4f5c\u5f00\u53d1\u6d3b\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u6280\u672f<\/div>\n
5.\u9ed8\u6c99\u4e1c\u4e0eOrna Therapeutics\u516c\u53f8\u8fbe\u6210\u73af\u72b6RNA\u7597\u6cd5\u7684\u5408\u4f5c<\/div>\n
6.\u534e\u5927\u667a\u9020\uff1a\u56fd\u4ea7\u57fa\u56e0\u6d4b\u5e8f\u8bbe\u5907\u7b2c\u4e00\u80a1\u5373\u5c06\u8fce\u6765\u79d1\u521b\u677f\u9996\u53d1<\/div>\n
\u2026\u2026<\/div>\n
\u66f4\u591a\u7cbe\u5f69\u8d44\u8baf\uff0c\u8bf7\u67e5\u9605\u672c\u671f\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5\uff01<\/div>\n
\u5b8f\u89c2\u73af\u5883<\/div>\n
\u2756\u00a0\u4e2d\u56fd\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u884c\u653f\u8bb8\u53ef\u4e8b\u98792022\u5e74\u7b2c28\u6279\u7b80\u5316\u6d41\u7a0b\u5ba1\u6279\u7ed3\u679c<\/div>\n
2022\u5e747\u670826\u65e5\u81f32022\u5e748\u67081\u65e5\u5171\u53d7\u7406\u7b26\u5408\u7b80\u5316\u5ba1\u6279\u6d41\u7a0b\u7533\u8bf7\u4e8b\u987973\u9879\uff0c\u540c\u610f\u5f00\u5c5573\u9879\u3002\u4ee5\u4e0b1\u4f8b\u4e3a\u7b80\u5316\u6d41\u7a0b\u83b7\u6279\u9879\u76ee\u4ee3\u8868\uff1a<\/div>\n
\u4eba\u5faa\u73af\u80bf\u7624 DNA \u591a\u57fa\u56e0\u7a81\u53d8\u8054\u5408\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08\u98de\u884c\u65f6\u95f4\u8d28\u8c31\u6cd5\uff09\u4e34\u5e8a\u8bd5\u9a8c\u2014\u2014\u5317\u4eac\u80bf\u7624\u533b\u9662\u3001\u4e2d\u6e90\u7ef4\u5eb7\uff08\u5929\u6d25\uff09\u533b\u5b66\u68c0\u9a8c\u6240\u6709\u9650\u516c\u53f8\u3001\u5317\u4eac\u6c34\u6728\u83c1\u521b\u533b\u836f\u79d1\u6280\u6709\u9650\u516c\u53f8\u3001\u5317\u4eac\u5409\u56e0\u52a0\u533b\u5b66\u68c0\u9a8c\u5b9e\u9a8c\u5ba4\u6709\u9650\u516c\u53f8<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/fuwu.most.gov.cn\/html\/tztg\/xzxkzx\/20220811\/123124340.html<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0NMPA\u6279\u51c6\uff1a\u9996\u6b3e\u4e2d\u7f8e\u6b27\u540c\u65f6\u83b7\u6279\u7684\u591a\u764c\u79cdNGS\u901a\u7528\u4f34\u968f\u8bca\u65ad\u8bd5\u5242\u76d2\u4e0a\u5e02<\/div>\n
2022\u5e748\u670817\u65e5\uff0c\u4e0a\u6d77\u771f\u56fa\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\u6ce8\u518c\u7533\u62a5\u7684\u201c\u4ebaKRAS\/BRAF\/PIK3CA\u57fa\u56e0\u7a81\u53d8\u68c0\u6d4b\u8bd5\u5242\u76d2\uff08\u53ef\u9006\u672b\u7aef\u7ec8\u6b62\u6d4b\u5e8f\u6cd5\uff09\u201d\u6b63\u5f0f\u83b7\u5f97NMPA\u6279\u51c6\u4e0a\u5e02\u3002\u6b64\u6b3e\u4ea7\u54c1\u6b64\u524d\u5df2\u83b7FDA&CE\u6279\u51c6\u7528\u4e8e\u591a\u764c\u79cd\u4f34\u968f\u8bca\u65ad\uff08\u80a0\u764c&\u80ba\u764c\uff09\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nmpa.gov.cn\/zwfw\/sdxx\/sdxxylqx\/qxpjfb\/20220819124259134.html<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0FDA\u6279\u51c6\uff1a\u7528\u4e8e\u6cbb\u7597\u03b2-\u5730\u4e2d\u6d77\u8d2b\u8840\u7684\u57fa\u56e0\u7597\u6cd5<\/div>\n
2022\u5e748\u670817\u65e5\uff0cBluebird Bio\u7684\u7528\u4e8e\u6cbb\u7597\u03b2-\u5730\u4e2d\u6d77\u8d2b\u8840\u7684\u57fa\u56e0\u7597\u6cd5betibeglogene autotemcel\uff08\u5546\u54c1\u540d\u4e3aZynteglo\uff09\u83b7\u5f97\u7f8e\u56fdFDA\u6279\u51c6\u3002\u8fd9\u662f\u7f8e\u56fd\u9996\u4e2a\u83b7\u6279\u7684\u9488\u5bf9\u03b2-\u5730\u4e2d\u6d77\u8d2b\u8840\u60a3\u8005\u6f5c\u5728\u9057\u4f20\u75c5\u56e0\u7684\u4e00\u6b21\u6027\u7597\u6cd5\uff0c\u5c06\u4e3a\u60a3\u8005\u63d0\u4f9b\u5e38\u89c4\u7ea2\u7ec6\u80de\u8f93\u6ce8\u548c\u94c1\u87af\u5408\u5242\u6cbb\u7597\u4ee5\u5916\u7684\u66ff\u4ee3\u65b9\u6848\u3002\u636e\u6089\uff0c\u6b64\u6b3e\u57fa\u56e0\u7597\u6cd5\u552e\u4ef7\u9ad8\u8fbe280\u4e07\u7f8e\u5143\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.fda.gov\/media\/159011\/download<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0EC\u6279\u51c6\uff1a\u5168\u7403\u9996\u6b3e\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u8840\u53cb\u75c5\u7532\u7684\u57fa\u56e0\u7597\u6cd5<\/div>\n
2022\u5e748\u670824\u65e5\uff0cBioMarin Pharmaceutical\u65d7\u4e0b\u7528\u4e8e\u6cbb\u7597\u91cd\u5ea6\u8840\u53cb\u75c5\u7532\u6210\u4eba\u60a3\u8005\u7684\u57fa\u56e0\u7597\u6cd5Roctavian\u2122\u5df2\u7531\u6b27\u76df\u59d4\u5458\u4f1a\uff08EC\uff09\u6279\u51c6\u9644\u6761\u4ef6\u4e0a\u5e02\u3002\u8fd9\u662f\u5168\u7403\u9996\u6b3e\u83b7\u6279\u7528\u4e8e\u6cbb\u7597\u8840\u53cb\u75c5\u7532\u7684\u57fa\u56e0\u7597\u6cd5\u3002<\/div>\n
\u00a0\u9644\u6279\u6761\u4ef6\uff1a<\/div>\n
\u9488\u5bf9\u672a\u80fd\u6ee1\u8db3\u7684\u533b\u7597\u9700\u6c42\uff08\u5982\uff1a\u5927\u90e8\u5206\u7f55\u89c1\u75c5\uff09\u7684\u836f\u7269\uff0c\u5728\u7533\u8bf7\u4eba\u672a\u80fd\u63d0\u4f9b\u6b63\u5e38\u8981\u6c42\u4e0b\u7684\u5168\u90e8\u6750\u6599\uff08\u5982\uff1a\u5b8c\u6574\u8bd5\u9a8c\u6570\u636e\uff09\u7684\u60c5\u51b5\u4e0b\uff0c\u4ecd\u6279\u51c6\u8be5\u836f\u7684\u4e0a\u5e02\u8bb8\u53ef\u3002\u6b64\u7c7b\u8bb8\u53ef\u7684\u6709\u6548\u671f\u4e3a\u4e00\u5e74\uff0c\u9700\u6bcf\u5e74\u5ba1\u67e5\u66f4\u65b0\u3002\u4e00\u65e6\u83b7\u5f97\u5b8c\u6574\u6570\u636e\uff0c\u53ef\u8f6c\u5316\u4e3a\u6b63\u5e38\u7684\u4e0a\u5e02\u8bb8\u53ef\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.biomarin.com\/<\/div>\n
\u00a0<\/div>\n
\u6280\u672f\u5e94\u7528<\/div>\n
\u2756\u00a0Immunity | \u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u98ce\u9669\u57fa\u56e0\u6216\u53ef\u4f5c\u4e3a\u9752\u5149\u773c\u6cbb\u7597\u6f5c\u5728\u9776\u70b9<\/div>\n
2022\u5e748\u670815\u65e5\uff0c\u54c8\u4f5b\u533b\u5b66\u9662Oleg\u00a0Butovsky\u7814\u7a76\u56e2\u961f\u5728Immunity\u4e0a\u520a\u6587\u3002\u53ef\u589e\u52a0\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u60a3\u75c5\u98ce\u9669\u7684\u8f7d\u8102\u86cb\u767dE4 (APOE4)\u7b49\u4f4d\u57fa\u56e0\uff0c\u5374\u80fd\u51cf\u5f31\u5c0f\u80f6\u8d28\u7ec6\u80de\u795e\u7ecf\u9000\u884c\u6027\u75be\u75c5\u8868\u578b\uff0c\u5728\u9752\u5149\u773c\u6a21\u578b\u4e2d\u4fdd\u62a4\u795e\u7ecf\u8282\u7ec6\u80de\u7684\u4f5c\u7528\uff0c\u964d\u4f4e\u5e74\u9f84\u76f8\u5173\u7684\u9752\u5149\u773c\u60a3\u75c5\u98ce\u9669\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cell.com\/immunity\/fulltext\/S1074-7613(22)00349-1<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Nature | \u5f00\u53d1\u6d3b\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u6280\u672f\u00a0<\/div>\n
2022\u5e748\u670817\u65e5\uff0c\u4e2d\u56fd\u79d1\u5b66\u9662\u6df1\u5733\u5148\u8fdb\u6280\u672f\u7814\u7a76\u9662\u4e0e\u745e\u58eb\u6d1b\u6851\u8054\u90a6\u7406\u5de5\u5b66\u9662Bart Deplancke\u8bfe\u9898\u7ec4\u3001\u82cf\u9ece\u4e16\u8054\u90a6\u7406\u5de5\u5b66\u9662Julia Vorholt\u8bfe\u9898\u7ec4\u5408\u4f5c\u5728Nature\u520a\u6587\u3002\u8be5\u7814\u7a76\u5f00\u53d1\u4e86\u6d3b\u7ec6\u80de\u8f6c\u5f55\u7ec4\u6d4b\u5e8f\u6280\u672f\uff08Live-seq\uff09\uff0c\u8be5\u6280\u672f\u9996\u6b21\u8ba9\u5355\u7ec6\u80de\u8fdb\u884c\u8f6c\u5f55\u6d4b\u5e8f\u540e\u4f9d\u7136\u80fd\u4fdd\u6301\u7ec6\u80de\u5b58\u6d3b\uff0c\u5b9e\u73b0\u4e86\u6d3b\u7ec6\u80de\u5168\u57fa\u56e0\u8868\u8fbe\u7684\u8fde\u7eed\u89c2\u6d4b\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41586-022-05046-9<\/div>\n
\n
\u00a0<\/div>\n
\u2756 Cell | \u591a\u53d7\u4f53\u55c5\u89c9\u7cfb\u7edf\u786e\u4fdd\u868a\u5b50\u603b\u662f\u80fd\u95fb\u5230\u4eba\u7c7b\u7684\u5473\u9053<\/div>\n
2022\u5e748\u670818\u65e5\uff0c\u6d1b\u514b\u83f2\u52d2\u5927\u5b66Leslie Vosshall\u6559\u6388\u56e2\u961f\u5728Cell\u4e0a\u520a\u6587\u3002\u901a\u8fc7\u4f7f\u7528\u57fa\u56e0\u7f16\u8f91\u5de5\u5177CRISPR\u3001\u5355\u6838RNA\u6d4b\u5e8f\uff08snRNA-seq\uff09\u3001\u7535\u6781\u63d2\u5165\u7b49\u65b9\u6cd5\uff0c\u53d1\u73b0\u868a\u5b50\u7684\u5355\u4e2a\u55c5\u89c9\u795e\u7ecf\u5143\u5b58\u5728\u591a\u79cd\u7c7b\u578b\u7684\u5316\u5b66\u53d7\u4f53\uff0c\u53ef\u4ee5\u63a2\u6d4b\u5230\u4e0d\u540c\u7684\u6c14\u5473\uff0c\u786e\u4fdd\u5b83\u4eec\u603b\u662f\u80fd\u95fb\u5230\u4eba\u7c7b\u7684\u6c14\u5473\u5e76\u53ee\u54ac\u6211\u4eec\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.cell.com\/cell\/fulltext\/S0092-8674(22)00927-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867422009278%3Fshowall%3Dtrue<\/div>\n
\u00a0<\/div>\n<\/div>\n
\n
\u2756\u00a0Nat Genet | \u767e\u4e07\u8de8\u7956\u5148\u5168\u57fa\u56e0\u7ec4\u835f\u8403\u5206\u6790\uff0c\u9274\u5b9a\u65b0\u7684\u80ba\u764c\u6613\u611f\u4f4d\u70b9<\/div>\n
\u8fd1\u671f\uff0c\u7f8e\u56fd\u8d1d\u52d2\u533b\u5b66\u9662\u3001\u7f8e\u56fd\u56fd\u7acb\u764c\u75c7\u7814\u7a76\u6240\u3001\u4e2d\u56fd\u5357\u4eac\u533b\u79d1\u5927\u5b66\u7b49\u56fd\u9645\u8054\u5408\u7814\u7a76\u56e2\u961f\uff0c\u5728Nature Genetics\u520a\u6587\uff0c\u5bf9\u6765\u81ea\u6b27\u6d32\u3001\u4e1c\u4e9a\u548c\u975e\u6d32\u768461047\u4f8b\u75c5\u4f8b\u3001947237\u4f8b\u5bf9\u7167\u8fdb\u884c\u4e86\u8de8\u7956\u5148\u4ee3\u9645\u7684\u591a\u4eba\u79cd\u5168\u57fa\u56e0\u7ec4\u835f\u8403\u5206\u6790\uff0c\u53d1\u73b0\u4e865\u4e2a\u65b0\u7684\u80ba\u764c\u6613\u611f\u57fa\u56e0\u548c10\u4e2a\u5df2\u77e5\u98ce\u9669\u57fa\u56e0\u7684\u65b0\u53d8\u5f02\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.nature.com\/articles\/s41588-022-01115-x<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u53d1\u5c55<\/div>\n
\u2756\u00a0Illumina\uff1a\u4e0a\u6d77\u9996\u4e2a\u57fa\u56e0\u6d4b\u5e8f\u751f\u4ea7\u57fa\u5730\u542f\u7528<\/div>\n
2022\u5e748\u670825\u65e5\uff0cIllumina\u5728\u6caa\u6b63\u5f0f\u542f\u7528\u5728\u534e\u9996\u4e2a\u57fa\u56e0\u6d4b\u5e8f\u751f\u4ea7\u5236\u9020\u57fa\u5730\uff0c\u5e76\u8ba1\u5212\u672a\u6765\u4e94\u5e74\u9010\u6b65\u5b9e\u73b0\u9ad8\u7aef\u57fa\u56e0\u6d4b\u5e8f\u4eea\u53ca\u8017\u6750\u5168\u9762\u672c\u571f\u5316\u751f\u4ea7\u3002\u9879\u76ee\u4e00\u671f\u603b\u6295\u8d44\u989d\u8fd15,000\u4e07\u4eba\u6c11\u5e01\uff0c\u516c\u53f8\u8ba1\u5212\u672a\u67655\u5e74\u5c06\u6295\u8d44\u8d854.5\u4ebf\u5143\u4ee5\u5efa\u8bbe\u5728\u534e\u751f\u4ea7\u5236\u9020\u80fd\u529b\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/r1lJ5GvSBCpN1Gp_QpH4nQ<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u9ed8\u6c99\u4e1c\u4e0eOrna Therapeutics\u516c\u53f8\u8fbe\u6210\u73af\u72b6RNA\u7597\u6cd5\u7684\u5408\u4f5c<\/div>\n
2022\u5e748\u670816\u65e5\uff0c\u9ed8\u6c99\u4e1c\u4e0eOrna Therapeutics\u516c\u53f8\u8fbe\u6210\u5408\u4f5c\uff0c\u5171\u540c\u5f00\u53d1\u65b0\u7684\u5b8c\u5168\u5de5\u7a0b\u5316\u7684\u73af\u72b6RNA\u7597\u6cd5\uff08oRNA\uff09\uff0c\u5305\u62ec\u4f20\u67d3\u75c5\u548c\u80bf\u7624\u5b66\u9886\u57df\u7684\u75ab\u82d7\u548c\u6cbb\u7597\u65b9\u6cd5\u3002\u6839\u636e\u534f\u8bae\uff0cOrna\u516c\u53f8\u5c06\u83b7\u5f971.5\u4ebf\u7f8e\u5143\u9884\u4ed8\u6b3e\u548c\u9ad8\u8fbe35\u4ebf\u7f8e\u5143\u7684\u91cc\u7a0b\u7891\u4ed8\u6b3e\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.msd.com\/<\/div>\n
\u00a0<\/div>\n<\/div>\n
\n
\u2756\u00a0\u534e\u5927\u667a\u9020\uff1a\u56fd\u4ea7\u57fa\u56e0\u6d4b\u5e8f\u8bbe\u5907\u7b2c\u4e00\u80a1\u5373\u5c06\u8fce\u6765\u79d1\u521b\u677f\u9996\u53d1<\/div>\n
2022\u5e748\u670822\u65e5\uff0c\u534e\u5927\u667a\u9020\u6b63\u5f0f\u542f\u52a8\u62db\u80a1\u5de5\u4f5c\uff0c\u8ba1\u5212\u767b\u9646\u79d1\u521b\u677f\uff0c\u8fd9\u610f\u5473\u7740\u534e\u5927\u96c6\u56e2\u5c06\u7ee7\u534e\u5927\u57fa\u56e0\u540e\u518d\u6dfb\u4e00\u5bb6\u4e0a\u5e02\u5e73\u53f0\u3002\u636e\u62db\u80a1\u4e66\u62ab\u9732\uff0c\u534e\u5927\u667a\u9020\u672c\u6b21\u62df\u516c\u5f00\u53d1\u884c\u4e0d\u8d85\u8fc74131.9475\u4e07\u80a1\uff0c\u8ba1\u5212\u52df\u96c6\u8d44\u91d125.28\u4ebf\u5143\uff0c\u7528\u4e8e\u667a\u80fd\u5236\u9020\u53ca\u7814\u53d1\u57fa\u5730\u9879\u76ee\u3001\u57fa\u4e8e\u534a\u5bfc\u4f53\u6280\u672f\u7684\u57fa\u56e0\u6d4b\u5e8f\u4eea\u53ca\u914d\u5957\u8bbe\u5907\u8bd5\u5242\u7814\u53d1\u751f\u4ea7\u9879\u76ee\u3001\u7814\u53d1\u4e2d\u5fc3\u9879\u76ee\u7b49\u3002\u4eca\u5e74\u4e0a\u534a\u5e74\uff0c\u516c\u53f8\u8425\u4e1a\u6536\u5165\u4e3a23.61\u4ebf\u5143\uff0c\u540c\u6bd4\u4e0a\u534720.52%\u3002\u5728\u4e1a\u52a1\u53ca\u4ea7\u54c1\u7ed3\u6784\u65b9\u9762\uff0c\u57fa\u56e0\u6d4b\u5e8f\u4eea\u4e1a\u52a1\u6536\u5165\u4e3a\u516c\u53f8\u5883\u5185\u8425\u4e1a\u6536\u5165\u7684\u4e3b\u8981\u6536\u5165\u6765\u6e90\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.sse.com.cn\/disclosure\/listedinfo\/announcement\/c\/new\/2022-08-23\/688114_20220823_2_0XT0qsIl.pdf<\/div>\n
\u00a0<\/div>\n<\/div>\n
\n
\u2756\u00a0\u8fd1\u5cb8\u86cb\u767d\uff1amRNA\u539f\u6599\u9176\u884c\u4e1a\u7b2c\u4e00\u80a1\u5373\u5c06\u8fce\u6765\u79d1\u521b\u677f\u9996\u53d1<\/div>\n
2022\u5e748\u670823\u65e5\uff0c\u8bc1\u76d1\u4f1a\u5b98\u7f51\u53d1\u5e03\u6d88\u606f\uff0c\u540c\u610f\u82cf\u5dde\u8fd1\u5cb8\u86cb\u767d\u8d28\u79d1\u6280\u80a1\u4efd\u6709\u9650\u516c\u53f8\uff08\u8fd1\u5cb8\u86cb\u767d\uff09\u79d1\u521b\u677fIPO\u6ce8\u518c\uff0c\u6807\u5fd7\u7740\u56fd\u5185mRNA\u539f\u6599\u9176\u7b2c\u4e00\u80a1\u5373\u5c06\u4e0a\u5e02\u3002\u6839\u636eFrost& Sullivan\u6570\u636e\uff0c\u5728\u56fd\u5185mRNA\u539f\u6599\u9176\u53ca\u8bd5\u5242\u5e02\u573a\uff0c\u8fd1\u5cb8\u86cb\u767d\u5728\u56fd\u5185\u5382\u5bb6\u6392\u540d\u4e2d\u4f4d\u5217\u7b2c\u4e00\uff0c\u76f8\u5173\u4ea7\u54c1\u5df2\u7ecf\u8fbe\u5230\u56fd\u9645\u5148\u8fdb\u6c34\u5e73\uff0c2021\u5e74\u5ea6\u5df2\u7ecf\u5360\u636e\u56fd\u5185\u5e02\u573a39.80%\u7684\u5e02\u573a\u4efd\u989d\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>http:\/\/www.csrc.gov.cn\/csrc\/c105906\/c5558720\/content.shtml<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Sema4\uff1a\u00a0\u88c1\u545813%\uff0c\u521b\u59cb\u4ebaSchadt\u79bb\u804c<\/div>\n
2022\u5e748\u670815\u65e5\uff0c\u57fa\u56e0\u7ec4\u5b66\u548c\u4e34\u5e8a\u6570\u636e\u667a\u80fd\u516c\u53f8\u2014\u2014Sema4\u516c\u5e03\u5176\u7b2c\u4e8c\u5b63\u5ea6\u6536\u5165\u4e3a3620\u4e07\u7f8e\u5143\uff0c\u540c\u6bd4\u4e0b\u964d\u4e8623%\u3002Sema4\u540c\u65f6\u5ba3\u5e03\u5c06\u8fdb\u884c\u4e00\u7cfb\u5217\u7684\u91cd\u7ec4\u884c\u4e3a\uff0c\u5176\u4e2d\u5305\u62ec\u88c1\u51cf250\u4e2a\u804c\u4f4d\uff0c\u7ea6\u5360\u5176\u5458\u5de5\u603b\u6570\u768413%\uff0c\u5e76\u4e14\u8be5\u516c\u53f8\u521b\u59cb\u4eba\u3001\u603b\u88c1\u548c\u9996\u5e2d\u7814\u53d1\u5b98Eric Schadt\u5c06\u79bb\u804c\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.genomeweb.com\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0Ginkgo Bioworks\uff1a\u62a5\u544a\u7b2c\u4e8c\u5b63\u5ea6\u6536\u5165\u8d85\u8fc7\u4e09\u500d<\/div>\n
2022\u5e748\u670815\u65e5\uff0c\u57fa\u56e0\u5de5\u7a0b\u751f\u4ea7\u5de5\u4e1a\u5e94\u7528\u7ec6\u83cc\u7684\u751f\u7269\u6280\u672f\u516c\u53f8\u2014\u2014Ginkgo Bioworks\u516c\u5e03\u51762022\u5e74\u7b2c\u4e8c\u5b63\u5ea6\u7684\u6536\u51651.446\u4ebf\u7f8e\u5143\uff0c\u540c\u6bd4\u589e\u957f 231%\u3002\u8be5\u516c\u53f8\u5c06\u51762022\u5e74\u603b\u6536\u5165\u6307\u5f15\u63d0\u9ad8\u81f34.25\u4ebf\u7f8e\u5143\u81f34.4\u4ebf\u7f8e\u5143\u4e4b\u95f4\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.genomeweb.com\/<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u8fd1\u671f\u56fd\u5185\u4e94\u5bb6\u57fa\u56e0\u4f01\u4e1a\u878d\u8d44\uff1a\u00a0\u535a\u817e\u751f\u7269\u3001\u7693\u9633\u751f\u7269\u3001\u81fb\u683c\u751f\u7269\u3001\u6108\u65b9\u751f\u7269\u3001\u4e91\u68c0\u533b\u5b66<\/div>\n<\/div>\n\n
\n
\"RmFicvQBAkgAgQ6KtqZ7epwl8UiaiceVag9hEYYebbSRpia7zjibibZCdOQsDFP5sp9us4CLZNTLmicVficzMepAy7iaS9Q\"\/<\/figure><\/div>\n\n
\u535a\u817e\u751f\u7269\u4e13\u6ce8\u57fa\u56e0\u4e0e\u7ec6\u80de\u6cbb\u7597CDMO\u670d\u52a1\u3002\u672c\u8f6e\u878d\u8d44\u5c06\u7528\u4e8e\u8fdb\u4e00\u6b65\u63a8\u8fdb\u516c\u53f8\u5168\u7403\u5316\u5e03\u5c40\uff0c\u52a0\u5feb\u5546\u4e1a\u5316\u751f\u4ea7\u57fa\u5730\u7684\u5efa\u8bbe\u53ca\u8fd0\u8425\uff0c\u52a0\u901f\u7aef\u5230\u7aef\u7684\u57fa\u56e0\u4e0e\u7ec6\u80de\u6cbb\u7597CDMO\u5e73\u53f0\u7684\u5b8c\u5584\u3002<\/div>\n
\u7693\u9633\u751f\u7269\u662f\u4e00\u5bb6\u4e13\u95e8\u4ece\u4e8b\u6297\u4f53\u548c\u91cd\u7ec4\u86cb\u767d\u7c7b\u836f\u7269\u5f00\u53d1\u7684\u6280\u672f\u670d\u52a1\u516c\u53f8\u3002\u672c\u8f6e\u878d\u8d44\u5c06\u7528\u4e8e\u5b8c\u5584\u4eba\u5458\u56e2\u961f\u3001\u5efa\u8bbe2000L\u751f\u4ea7\u7ebf\u4ee5\u53ca\u89e3\u51b3\u5916\u6ccc\u4f53\u3001mRNA\u548cAAV\u7684CMC\u96be\u70b9\u3002<\/div>\n
\u81fb\u683c\u751f\u7269\u4f5c\u4e3a\u4e00\u5bb6\u65b0\u5174\u7684\u5927\u5206\u5b50\u751f\u7269\u836fCDMO\u6280\u672f\u670d\u52a1\u4f9b\u5e94\u5546\u3002\u6b64\u6b21\u878d\u8d44\u662f\u5bf92022\u5e743\u6708\u5b8c\u6210\u7684C\u8f6e\u878d\u8d44\u7684\u8865\u5145\u3002<\/div>\n
\u6108\u65b9\u751f\u7269\u662f\u4e00\u5bb6\u9776\u5411\u7aef\u7c92\u673a\u5236\u7684\u57fa\u56e0\u6cbb\u7597\u836f\u7269\u5f00\u53d1\u4f01\u4e1a\u3002\u57fa\u4e8e\u56e2\u961f\u8fc7\u5f80\u5728\u65af\u5766\u798f\u7684\u524d\u6cbf\u7814\u7a76\uff0c\u6108\u65b9\u751f\u7269\u642d\u5efa\u4e86\u56fd\u9645\u9886\u5148\u7684\u65b0\u4e00\u4ee3\u7aef\u7c92\u7cbe\u51c6\u8c03\u63a7\u6280\u672f\u5e73\u53f0\uff0c\u4e13\u6ce8\u4e8e\u89e3\u51b3\u5fc3\u529b\u8870\u7aed\u7b49\u672a\u6ee1\u8db3\u7684\u4e34\u5e8a\u9700\u6c42\u3002<\/div>\n
\u4e91\u68c0\u533b\u5b66\u662f\u65b0\u4e00\u4ee3\u57fa\u4e8e\u86cb\u767d\u548c\u4ee3\u8c22\u7ec4\u5b66\u6807\u8bb0\u7269\u53d1\u73b0\u6280\u672f\u7684\u5e73\u53f0\u516c\u53f8\u3002\u672c\u8f6e\u878d\u8d44\u4e3b\u8981\u7528\u4e8e\u8fdb\u4e00\u6b65\u6269\u5145\u516c\u53f8\u5987\u5e7c\u4ea7\u54c1\u7ebf\u53ca\u764c\u75c7\u68c0\u6d4b\u4ea7\u54c1\u7814\u53d1\u7ba1\u7ebf\uff0c\u5e76\u6301\u7eed\u63a8\u8fdb\u5404\u4ea7\u54c1\u7ebf\u5728\u4e2d\u7f8e\u4e24\u5730\u7684\u6ce8\u518c\u751f\u4ea7\u3001\u5546\u4e1a\u5316\u843d\u5730\u548c\u56fd\u9645\u5e02\u573a\u7684\u5f00\u62d3\u3002<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u8fd1\u671f\u56fd\u5916\u4e24\u5bb6\u57fa\u56e0\u4f01\u4e1a\u878d\u8d44\uff1a<\/div>\n
Senda Biosciences\u3001Biotia<\/div>\n\n
\n
\"RmFicvQBAkgAgQ6KtqZ7epwl8UiaiceVag9ZhDhHZqSQHGqJvuQDxIsvKjJFficenXUVPBtu4X4Znms6zEgBRBHhcg\"\/<\/figure><\/div>\n\n
Senda Biosciences\u662f\u4e00\u5bb6\u5229\u7528\u81ea\u7136\u6765\u89c4\u5212\u9776\u5411\u3001\u5f3a\u6548\u548c\u53ef\u8c03\u836f\u7269\u7684\u516c\u53f8\u3002\u672c\u6765\u878d\u8d44\u5c06\u7528\u4e8e\u63a8\u52a8\u68ee\u8fbe\u4e13\u6709\u53ef\u7f16\u7a0b\u836f\u7269\u5e73\u53f0\u7684\u8fdb\u4e00\u6b65\u53d1\u5c55\uff0c\u5e76\u5c06\u5176\u9996\u4e2a\u9879\u76ee\u63a8\u8fdb\u4e34\u5e8a\u8bd5\u9a8c\u3002<\/div>\n
Biotia\u662f\u4e00\u5bb6\u5229\u7528\u57fa\u56e0\u7ec4\u5b66\u548c\u4eba\u5de5\u667a\u80fd\u7cbe\u51c6\u53d1\u73b0\u4f20\u67d3\u75c5\u7684\u516c\u53f8\u3002\u672c\u6765\u878d\u8d44\u5c06\u7528\u4e8e\u8fc5\u901f\u6269\u5927\u5176\u6280\u672f\u80fd\u529b\u548c\u8425\u9500\u8303\u56f4\uff0c\u5411\u53c2\u4e0e\u5168\u7403\u4f20\u67d3\u75c5\u8bca\u65ad\u3001\u7f13\u89e3\u548c\u63a7\u5236\u7684\u7ec4\u7ec7\u63d0\u4f9b\u670d\u52a1\uff0c\u5e76\u786e\u4fdd\u5176\u4ea7\u54c1\u7b26\u5408\u76d1\u7ba1\u89c4\u5219\u3002<\/div>\n
\u00a0<\/div>\n
\u4f1a\u8bae\u63a8\u8350<\/div>\n
\u2756\u00a0\u7b2c\u5341\u56db\u5c4a\u4e2d\u56fd\u6574\u5408\u751f\u7269\u6837\u672c\u5b66\u5927\u4f1a\u66a8\u7b2c\u4e5d\u5c4a\u4e2d\u56fd\u751f\u7269\u6837\u672c\u5e93\u9662\u957f\u9ad8\u5cf0\u8bba\u575b<\/div>\n
2022\u5e748\u670826\u81f328\u65e5\uff0c\u5929\u6d25\u5e02\uff0c\u4e2d\u56fd\u533b\u836f\u751f\u7269\u6280\u672f\u534f\u4f1a\u3001\u4e2d\u56fd\u533b\u5b66\u79d1\u5b66\u9662\u4e3b\u529e<\/div>\n
\u00a0<\/div>\n
\u2756 2022\u5e74\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\uff08ESMO\uff09\u5e74\u4f1a<\/div>\n
2022\u5e749\u67089\u81f313\u65e5\uff0c\u6cd5\u56fd\u5df4\u9ece\uff0c\u6b27\u6d32\u80bf\u7624\u5185\u79d1\u5b66\u4f1a\uff08ESMO\uff09\u4e3b\u529e<\/div>\n
\u00a0<\/div>\n
\u2756\u00a0\u7b2c\u56db\u5c4a\u7ca4\u6e2f\u6fb3\u5927\u6e7e\u533a\u751f\u7269\u533b\u836f\u521b\u65b0\u9ad8\u5cf0\u8bba\u575b<\/div>\n
2022\u5e749\u670815\u65e5\uff0c\u5e7f\u5dde\u5e02\uff0c\u5e7f\u4e1c\u7701\u751f\u7269\u533b\u836f\u521b\u65b0\u6280\u672f\u534f\u4f1a\u4e3b\u529e<\/div>\n
\u7f16\u8f91 | MN<\/div>\n
\u6821\u5bf9 | \u4f0a\u83b9\u3001\u5b66\u4e3d\u3001\u5b50\u7426<\/div>\n
\u5ba1\u6838 | \u5a01\u950b<\/div>\n
\u6269\u5c55\u9605\u8bfb<\/div>\n
\u4e07\u7269DNA\uff1fDNA\u5b58\u50a8\u7a76\u7adf\u5e94\u7528\u4e8e\u4f55\u5904\u00a0<\/a><\/div>\n
\u5b58\u50a8\u4ecb\u8d28\u7684\u201c\u9ed1\u79d1\u6280\u201d\uff0c\u5f15\u53d1\u4e0b\u4e00\u4ee3\u6570\u636e\u5b58\u50a8\u9769\u547d?<\/a><\/div>\n
\u4e00\u516c\u65a4DNA\u53ef\u5b58\u50a8\u5168\u7403\u6570\u636e\u662f\u5982\u4f55\u505a\u5230\u7684\uff1f\u00a0<\/a><\/div>\n
\u3010\u58f0\u660e\u3011\u4e3a\u4e86\u63a8\u52a8\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u79d1\u6280\u63a8\u5e7f\u3001\u4ea7\u4e1a\u53d1\u5c55\u53ca\u653f\u4ea7\u5b66\u7814\u7528\u8fde\u63a5\uff0c\u57fa\u56e0\u6167\u79c9\u6301\u4e13\u4e1a\u3001\u8d4b\u80fd\u3001\u4e2d\u7acb\u7684\u7acb\u573a\u6536\u96c6\u3001\u5206\u6790\u53ca\u53d1\u5e03\u76f8\u5173\u4fe1\u606f\u3002\u4f46\u7531\u4e8e\u65f6\u6548\u6027\u53ca\u884c\u4e1a\u7279\u6b8a\u6027\uff0c\u6240\u520a\u767b\u5185\u5bb9\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u672a\u7ecf\u8bf4\u660e\u4e0d\u4f5c\u4e3a\u51b3\u7b56\u4f9d\u636e\uff1b\u672c\u6587\u76f8\u5173\u4fe1\u606f\u4e0d\u4ee3\u8868\u57fa\u56e0\u6167\u7684\u89c2\u70b9\uff1b\u57fa\u56e0\u6167\u5e73\u53f0\u520a\u767b\u7684\u539f\u521b\u5185\u5bb9\u7684\u77e5\u8bc6\u4ea7\u6743\u4e3a\u201c\u57fa\u56e0\u6167\u201d\u5546\u6807\u62e5\u6709\u8005\u53ca\u76f8\u5173\u6743\u5229\u4eba\u6240\u6709\uff1b\u6b22\u8fce\u8f6c\u8f7d\uff0c\u8f6c\u8f7d\u8bf7\u7533\u8bf7\u5e76\u6ce8\u660e\u6765\u6e90\u3002\u6b22\u8fce\u4e2a\u4eba\u53ca\u673a\u6784\u6295\u7a3f\u53ca\u5408\u4f5c\u3002<\/div>\n
\u00a0<\/div>\n
\u00a0\u5173\u4e8e\u57fa\u56e0\u6167\u00a0<\/div>\n
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