{"id":7968,"date":"2023-06-05T08:00:00","date_gmt":"2023-06-05T00:00:00","guid":{"rendered":"https:\/\/www.geneclub.net.cn\/index.php\/2023\/06\/05\/535451\/"},"modified":"2026-04-01T09:10:32","modified_gmt":"2026-04-01T01:10:32","slug":"535451","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2023\/06\/05\/535451\/","title":{"rendered":"\u57fa\u56e0\u884c\u4e1a\u7b80\u62a5\uff08231\u671f\uff09"},"content":{"rendered":"

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\"RmFicvQBAkgA8vnIO8iasy6CtAiaeibiaZsqWmIWesVk8DKQ8PDcIfO5DAAaiagLqZtPor3icqiafb6RnYibhcFWia62EUCA\"\/<\/figure><\/div>\n\n

\u56fe:\u79d1\u5b66\u5bb6\u7834\u8bd1\u5305\u62ec\u5ddd\u91d1\u4e1d\u7334\u5728\u5185\u7684233\u79cd\u7075\u957f\u7c7b\u57fa\u56e0\u7ec4\uff08\u6765\u6e90\/Science\uff09<\/p>\n

\u5927\u73af\u5883<\/div>\n
\u2756 \u79d1\u6280\u90e8\u516c\u5e03\u300a\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u7ba1\u7406\u6761\u4f8b\u5b9e\u65bd\u7ec6\u5219\u300b<\/div>\n
2023\u5e746\u67081\u65e5\uff0c\u79d1\u6280\u90e8\u5370\u53d1\u300a\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u7ba1\u7406\u6761\u4f8b\u5b9e\u65bd\u7ec6\u5219\u300b\uff0c\u81ea2023\u5e747\u67081\u65e5\u8d77\u65bd\u884c\u3002\u5b9e\u65bd\u7ec6\u5219\u4e3a\u6709\u6548\u4fdd\u62a4\u548c\u5408\u7406\u5229\u7528\u6211\u56fd\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\uff1b\u91c7\u96c6\u3001\u4fdd\u85cf\u3001\u5229\u7528\u3001\u5bf9\u5916\u63d0\u4f9b\u6211\u56fd\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\uff0c\u5e94\u5f53\u9075\u5b88\u672c\u5b9e\u65bd\u7ec6\u5219\u3002\u7ec6\u5219\u89c4\u5b9a\uff0c\u5883\u5916\u7ec4\u7ec7\u53ca\u4e2a\u4eba\u8bbe\u7acb\u6216\u8005\u5b9e\u9645\u63a7\u5236\u7684\u673a\u6784\u4ee5\u53ca\u5883\u5916\u4e2a\u4eba\u4e0d\u5f97\u5411\u5883\u5916\u63d0\u4f9b\u6211\u56fd\u4eba\u7c7b\u9057\u4f20\u8d44\u6e90\u3002<\/div>\n
\u53c2\u8003\u4fe1\u606f>>https:\/\/www.most.gov.cn\/xxgk\/xinxifenlei\/fdzdgknr\/fgzc\/bmgz\/202306\/t20230601_186416.html<\/div>\n
\u00a0<\/div>\n
\u5927\u4f01\u4e1a<\/div>\n

\u2756\u7ec6\u80de\u548c\u57fa\u56e0\u6cbb\u7597\u516c\u53f8\u4f18\u8d5b\u8bfa\u751f\u7269\u5b8c\u62101.5\u4ebf\u5143A+\u8f6e\u878d\u8d44<\/p>\n

2023\u5e746\u67083\u65e5\uff0c\u6210\u90fd\u4f18\u8d5b\u8bfa\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\u6210\u529f\u5b8c\u62101.5\u4ebf\u5143\u4eba\u6c11\u5e01A+\u8f6e\u878d\u8d44\u3002\u8be5\u8f6e\u878d\u8d44\u7531\u949c\u79d1\u6295\u8d44\u9886\u6295\uff0c\u56fd\u4e2d\u8d44\u672c\u3001\u9e4f\u6765\u8d44\u672c\u8ddf\u6295\u3002\u8001\u80a1\u4e1c\u56fd\u751f\u8d44\u672c\u3001\u7ecf\u7eac\u521b\u6295\u3001\u51ef\u98ce\u521b\u6295\u7ee7\u7eed\u52a0\u7801\u3002\u8d44\u91d1\u5c06\u7528\u4e8e\u52a0\u5feb\u516c\u53f8\u5f02\u4f53\u901a\u7528\u578bCAR-T\u7ec6\u80de\u6cbb\u7597\u4ea7\u54c1\u7684\u4ea7\u4e1a\u5316\u6b65\u4f10\uff0c\u63a8\u8fdb\u65b0\u836f\u7533\u62a5\u53ca\u4e0a\u5e02\u8fdb\u7a0b\u3002<\/p>\n

\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/WDr89rc91TN-LkltQ-MW9Q<\/div>\n
\u00a0<\/div>\n

\u2756\u9e4d\u8fdc\u751f\u7269\u8054\u5408\u97e9\u56fdClinomics\u5b50\u516c\u53f8\u5728\u7f8e\u56fd\u63a8\u51fa\u764c\u75c7\u65e9\u68c0\u670d\u52a1<\/p>\n

2023\u5e745\u670829\u65e5\uff0c\u9e4d\u8fdc\u751f\u7269\u4e0e\u97e9\u56fdClinomics\u65d7\u4e0b\u5b50\u516c\u53f8Clinomics USA\u7b7e\u8ba2\u6218\u7565\u5408\u4f5c\u534f\u8bae\u3002\u53cc\u65b9\u5c06\u5728\u5168\u7403\u8303\u56f4\u5f00\u5c55\u57fa\u4e8e\u8840\u6db2\u7684\u764c\u75c7\u65e9\u671f\u68c0\u6d4b\u548c\u8bca\u65ad\u4e1a\u52a1\uff0c\u7531\u7f8e\u56fdClinomics Irvine CLIA Lab\u5411\u5e02\u573a\u63a8\u51fa\u9e4d\u8fdc\u751f\u7269\u81ea\u4e3b\u7814\u53d1\u7684ColonES\u00ae\uff08\u7ed3\u76f4\u80a0\u764c\uff09\u3001PDACatch\u2122\uff08\u80f0\u817a\u764c\uff09\u548c PanSeer\u00ae\uff08\u6cdb\u764c\u79cd\u7b5b\u67e5\u6280\u672f\uff09\u68c0\u6d4b\u670d\u52a1\u3002<\/p>\n

\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/qpLSUQbRBITameYRrGvnyA<\/div>\n
\u00a0<\/div>\n

\u2756\u00a0\u91d1\u65af\u745e\u65d7\u4e0b\u5408\u6210\u751f\u7269\u5b66\u516c\u53f8\u767e\u65af\u6770\u751f\u7269\u5b8c\u62102.5\u4ebf\u9996\u8f6e\u878d\u8d44<\/p>\n

2023\u5e745\u670828\u65e5\uff0c\u91d1\u65af\u745e\u751f\u7269\u5ba3\u5e03\u65d7\u4e0b\u5de5\u4e1a\u9176\u4e0e\u5408\u6210\u751f\u7269\u5b66\u516c\u53f8\u767e\u65af\u6770\u751f\u7269\u5b8c\u6210\u7ea62.5\u4ebf\u5143\u7684\u9996\u8f6e\u878d\u8d44\uff0c\u7531\u9ad8\u74f4\u8d44\u672c\u9886\u6295\u3001\u534e\u6cf0\u7d2b\u91d1\u3001\u7f6e\u67cf\u6295\u8d44\u3001\u6d77\u5357\u8431\u6e7e\u3001\u65b0\u534e\u6d77\u96c6\u56e2\u3001\u5357\u4eac\u5229\u65ed\u3001\u6d77\u5357\u6d77\u76c8\u3001\u534e\u6cf0\u91d1\u65af\u745e\u57fa\u91d1\u53c2\u4e0e\u6295\u8d44\u3002<\/p>\n

\u53c2\u8003\u4fe1\u606f>>https:\/\/stockn.xueqiu.com\/01548\/20230528907393.pdf<\/div>\n
\u00a0<\/div>\n

\u2756 \u7f8e\u56fd\u75ab\u82d7\u5382\u5546Moderna\u843d\u5730\u4e0a\u6d77<\/p>\n

2023\u5e745\u670824\u65e5\uff0c\u7f8e\u56fd\u75ab\u82d7\u5382\u5546Moderna\u516c\u53f8\u5728\u4e2d\u56fd\u4e0a\u6d77\u6ce8\u518c\u4e86\u7f8e\u5fb7\u7eb3\uff08\u4e2d\u56fd\uff09\u751f\u7269\u79d1\u6280\u6709\u9650\u516c\u53f8\uff0c\u6ce8\u518c\u8d44\u672c1\u4ebf\u7f8e\u5143\uff0c\u7531Moderna Biotech\u82f1\u56fd\u516c\u53f8\u63a7\u80a1\u3002\u516c\u53f8\u7ecf\u8425\u8303\u56f4\u5305\u542b\u6280\u672f\u670d\u52a1\u3001\u6280\u672f\u5f00\u53d1\u3001\u6280\u672f\u54a8\u8be2\u3001\u6280\u672f\u4ea4\u6d41\u3001\u6280\u672f\u8f6c\u8ba9\u3001\u6280\u672f\u63a8\u5e7f\uff1b\u533b\u5b66\u7814\u7a76\u548c\u8bd5\u9a8c\u53d1\u5c55\uff1b\u8d27\u7269\u8fdb\u51fa\u53e3\u4e0e\u6280\u672f\u8fdb\u51fa\u53e3\u3002<\/p>\n

\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/Ntz5EOljzU9FA1aoNbviEQ<\/a><\/div>\n
\u00a0<\/div>\n
\u786c\u79d1\u6280<\/div>\n
\u2756 \u57fa\u4e8e\u6570\u767e\u4e07\u7075\u957f\u7c7b\u52a8\u7269\u826f\u6027\u53d8\u5f02\u8bad\u7ec3\u7684\u6df1\u5ea6\u5b66\u4e60\u6a21\u578bPrimateAI-3D<\/p>\n
2023\u5e746\u67082\u65e5\uff0cScience\u671f\u520a\u53d1\u6587\uff0c\u79d1\u5b66\u5bb6\u5bf9\u6765\u81ea233\u79cd\u975e\u4eba\u7075\u957f\u7c7b\u52a8\u7269\u7684800\u591a\u4e2a\u4e2a\u4f53\u8fdb\u884c\u4e86\u6d4b\u5e8f\uff0c\u7ed3\u5408\u7075\u957f\u7c7b\u5e38\u89c1\u57fa\u56e0\u7ec4\u53d8\u5f02\u8bad\u7ec3\u6df1\u5ea6\u5b66\u4e60\u6a21\u578b-PrimateAI-3D\uff0c\u8fd9\u610f\u5473\u7740\u57fa\u56e0\u53d8\u5f02\u6216\u591a\u6001\u6027\u4e0e\u75be\u75c5\u4e4b\u95f4\u7684\u5173\u7cfb\u5c06\u8fdb\u4e00\u6b65\u63ed\u79d8\u3002<\/div>\n

\u53c2\u8003\u4fe1\u606f>>https:\/\/www.science.org\/doi\/10.1126\/science.abn8197<\/p>\n

 <\/p>\n

\u2756\u00a0Science\u8fde\u53d18\u7bc7\u8bba\u6587\uff0c\u4e2d\u5916\u79d1\u5b66\u5bb6\u63ed\u793a\u7075\u957f\u7c7b\u6f14\u5316\u7814\u7a76\u91cd\u5927\u8fdb\u5c55<\/p>\n

2023\u5e746\u67081\u65e5\uff0c\u4ee5\u6211\u56fd\u79d1\u5b66\u5bb6\u7ec4\u7ec7\u7684\u7075\u957f\u7c7b\u57fa\u56e0\u7ec4\u8ba1\u5212\u53d1\u5e03\u4e86\u9636\u6bb5\u6027\u6210\u679c\uff0c\u76f8\u5173\u5185\u5bb9\u4ee5\u7814\u7a76\u4e13\u520a\u7684\u5f62\u5f0f\u5728Science\u53d1\u88684\u7bc7\u8bba\u6587\uff0c\u540c\u671f\u8fd8\u53d1\u8868\u4e86\u4f5c\u4e3a\u8be5\u8ba1\u5212\u6269\u5c55\u7684\u56fd\u9645\u7075\u957f\u7c7b\u7814\u7a76\u8054\u76df\u76844\u7bc7\u8bba\u6587\u3002\u540c\u65f6\u8be5\u9879\u76ee\u6709\u53e6\u59163\u7bc7\u536b\u661f\u8bba\u6587\u540c\u65e5\u53d1\u8868\u4e8eScience Advances\u3001Nature Ecology & Evolution\u7b49\u671f\u520a\u3002<\/div>\n

\u53c2\u8003\u4fe1\u606f>>https:\/\/www.science.org\/doi\/10.1126\/science.abn7829<\/p>\n

 <\/p>\n

\u2756 \u65b0\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u65b9\u6cd5\u63ed\u793a\u764c\u75c7cfDNA\u5355\u5206\u5b50\u7532\u57fa\u5316\u8c31<\/div>\n
\u8fd1\u65e5\uff0c\u7f8e\u56fd\u65af\u5766\u798f\u5927\u5b66\u7684\u7814\u7a76\u56e2\u961f\u5728Genome Medicine\u53d1\u8868\u7814\u7a76\u6587\u7ae0\u201cSingle-molecule methylation profiles of cell-free DNA in cancer with nanopore sequencing\u201d\u3002\u4ecb\u7ecd\u4e86\u4e00\u79cd\u7eb3\u7c73\u5b54\u5355\u5206\u5b50\u6d4b\u5e8f\u65b9\u6cd5\uff0c\u7528\u4e8e\u6709\u6548\u8868\u5f81\u764c\u75c7\u60a3\u8005cfDNA\u7684\u7532\u57fa\u5316\u8c31\u3002\u8be5\u65b9\u6cd5\u53ef\u4ece\u7eb3\u514b\u7ea7\u6216\u66f4\u5c11\u91cf\u7684cfDNA\u4e2d\u751f\u6210\u6d4b\u5e8f\u6587\u5e93\uff0c\u5bf9\u764c\u75c7\u60a3\u8005\u7684\u5355\u4e2acfDNA\u6837\u672c\u4ea7\u751f2\u4ebf\u4e2areads\uff0c\u6bd4\u73b0\u6709\u7684\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u65b9\u6cd5\u63d0\u9ad8\u4e00\u4e2a\u6570\u91cf\u7ea7\u3002<\/div>\n

\u53c2\u8003\u4fe1\u606f>>https:\/\/genomemedicine.biomedcentral.com\/articles\/10.1186\/s13073-023-01178-3<\/p>\n

\u65b0\u4ea7\u54c1<\/div>\n
\u2756\u00a0FDA\u6279\u51c6\u5965\u62c9\u5e15\u5229\u7528\u4e8e\u6cbb\u7597BRCA\u7a81\u53d8\u76f8\u5173\u7684\u8f6c\u79fb\u6027\u53bb\u52bf\u62b5\u6297\u6027\u524d\u5217\u817a\u764c<\/p>\n
2023\u5e745\u670831\u65e5\uff0c\u7f8e\u56fdFDA\u6279\u51c6\u5965\u62c9\u5e15\u5229\uff08Lynparza\uff09\u8054\u5408\u963f\u6bd4\u7279\u9f99\u548c\u6cfc\u5c3c\u677e\u6216\u6cfc\u5c3c\u677e\u9f99\uff0c\u7528\u4e8e\u6cbb\u7597\u6709\u5bb3\u6216\u7591\u4f3c\u6709\u5bb3BRCA\u7a81\u53d8\u8f6c\u79fb\u6027\u53bb\u52bf\u62b5\u6297\u6027\u524d\u5217\u817a\u764c(mCRPC)\u3002<\/div>\n

\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/oQeqYLxIDj6ExiNK0_qcyg<\/p>\n

\u597d\u4f1a\u8bae<\/div>\n

\u2756 \u7b2c\u4e09\u5c4a\u57fa\u56e0\u79d1\u6280\u4e0e\u4ea7\u4e1a\u53d1\u5c55\u5927\u4f1a\u66a8\u300a2023\u57fa\u56e0\u884c\u4e1a\u84dd\u76ae\u4e66\u300b\u53d1\u5e03\u4f1a\uff0c\u5e7f\u4e1c\u7701\u6df1\u5733\u5e02\uff0c2023\u5e746\u670830\u65e5<\/p>\n

\u7531\u57fa\u56e0\u6167\u4e3b\u529e\u3001\u6df1\u5733\u5e02\u5065\u5eb7\u4ea7\u4e1a\u53d1\u5c55\u4fc3\u8fdb\u4f1a\u7b49\u534f\u529e\u7684\u7b2c\u4e09\u5c4a\u57fa\u56e0\u79d1\u6280\u4e0e\u4ea7\u4e1a\u53d1\u5c55\u5927\u4f1a\u66a8\u300a2023\u57fa\u56e0\u884c\u4e1a\u84dd\u76ae\u4e66\u300b\u53d1\u5e03\u4eea\u5f0f\u5c06\u4e8e2023\u5e746\u670830\u65e5\u5728\u6df1\u5733\u4e3e\u884c\uff0c\u4f1a\u4e0a\u57fa\u56e0\u6167\u5c06\u8054\u5408\u706b\u5c71\u5f15\u64ce\u3001\u534e\u5927\u667a\u9020\u3001\u7f57\u6c0f\u8bca\u65ad\u3001\u661f\u4e91\u57fa\u56e0\u3001\u9e4d\u8fdc\u751f\u7269\u3001Watchmaker\u3001\u58a8\u5353\u751f\u7269\u8fde\u7eed\u7b2c\u516d\u5e74\u53d1\u5e03\u300a2023\u57fa\u56e0\u884c\u4e1a\u84dd\u76ae\u4e66\u300b\uff0c\u8a79\u542f\u654f\u9662\u58eb\u3001\u5c39\u7231\u534e\u3001\u9ec4\u6770\u3001\u5468\u4f0a\u3001\u725f\u5cf0\u4ee5\u53ca\u76f8\u5173\u4f01\u4e1a\u8d1f\u8d23\u4eba\u7b49\u4e13\u5bb6\u53c2\u4e0e\u57fa\u56e0\u79d1\u6280\u53ca\u4ea7\u4e1a\u53d1\u5c55\u5927\u4f1a\u3002<\/p>\n

\u53c2\u8003\u4fe1\u606f>>https:\/\/mp.weixin.qq.com\/s\/tlXldZnpdWh5-7jp8OMKyw<\/div>\n

\u6b22\u8fce\u626b\u63cf\u4e0b\u65b9\u4e8c\u7ef4\u7801\u62a5\u540d\u53c2\u52a0\u4f1a\u8bae\uff1a<\/p>\n<\/div>\n<\/div>\n\n

\n
\"RmFicvQBAkgA8vnIO8iasy6CtAiaeibiaZsqW4Gib1GQzHdTDpx5V163cJY3gCRsiaVCZV2yibzSQNiaRdaCXfU9z0ibHyEw\"\/<\/figure><\/div>\n\n
\u626b\u7801\u62a5\u540d<\/div>\n
\u4f1a\u8bae\u8bda\u9080\u8d5e\u52a9\uff08\u5305\u62ec\u4f1a\u8bae\u51a0\u540d\u3001\u536b\u661f\u62a5\u544a\u4f1a\u3001\u6807\u51c6\u5c55\u53f0\u7b49\uff09\uff0c\u5177\u4f53\u53ef\u8054\u7cfb\u57fa\u56e0\u6167\u5546\u52a1Lily\uff1a<\/div>\n\n
\n
\"RmFicvQBAkgA7BWrv2VB0ia4DmQ9HW4icmBRlrehaY8nYk6w3nIyNyIiaiahMgblCicbOZIQ5foUicqhvxZjsbq8pbczQ\"\/<\/figure><\/div>\n\n
\u8d5e\u52a9\u8054\u7cfb<\/div>\n

\n\n

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\"RmFicvQBAkgA8vnIO8iasy6CtAiaeibiaZsqWSILgVMlbXDB8fLb22ajTSVfzCFnMDB9znlmjWoVl72xUSsgeCUt6fw\"\/<\/figure><\/div>\n\n
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