{"id":7966,"date":"2023-06-12T08:02:00","date_gmt":"2023-06-12T00:02:00","guid":{"rendered":"https:\/\/www.geneclub.net.cn\/index.php\/2023\/06\/12\/9856101\/"},"modified":"2026-03-19T11:52:49","modified_gmt":"2026-03-19T03:52:49","slug":"9856101","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2023\/06\/12\/9856101\/","title":{"rendered":"\u57fa\u56e0\u6167\u62a5\uff08232\u671f\uff09"},"content":{"rendered":"<p><!-- wechat_content_hash: b8e9c22f4e65bf1e --><\/p>\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgCanaVgDXB2DUclpSSTyQk4BNCkEnDNQA6AaNSatZR1icykiaEYQz57Z6DickYe3CdZZYX1criatgjmmg.png\" alt=\"RmFicvQBAkgCanaVgDXB2DUclpSSTyQk4BNCkEnDNQA6AaNSatZR1icykiaEYQz57Z6DickYe3CdZZYX1criatgjmmg\"\/><\/figure><\/div>\n\n<p style=\"text-align: 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style=\"text-align: center;\">\u786c\u79d1\u6280<\/div>\n<div>\u2756\u00a0\u534e\u5927\u7b49\u673a\u6784\u53d1\u6587\uff1acfRNA\u6216\u53ef\u9884\u6d4b\u5b50\u75eb\u524d\u671f\u98ce\u9669\n<p>\u8fd1\u65e5\uff0c\u6df1\u5733\u5e02\u9f99\u5c97\u533a\u5987\u5e7c\u4fdd\u5065\u9662\u3001\u6df1\u5733\u5e02\u5b9d\u5b89\u533a\u5987\u5e7c\u4fdd\u5065\u9662\u548c\u534e\u5927\u96c6\u56e2\u8054\u5408\u5728\u300a\u7f8e\u56fd\u5987\u4ea7\u79d1\u5b66\u6742\u5fd7\u300b\u4e0a\u53d1\u8868\u6700\u65b0\u7814\u7a76\uff0c\u901a\u8fc7\u56de\u987e\u6027\u961f\u5217\u7814\u7a76\uff0c\u5448\u73b0\u4e86\u5b50\u75eb\u524d\u671f\u60a3\u8005\u4e2d\u4e0d\u540c\u7c7b\u578b\u8840\u6d46\u6e38\u79bbRNA\u5206\u5b50\u7684\u8f6c\u5f55\u7ec4\u5168\u666f\u56fe\uff0c\u5e76\u57fa\u4e8e\u6b64\u5f00\u53d1\u4e86\u5728\u75c7\u72b6\u51fa\u73b0\u524d\u8fdb\u884c\u65e9\u4ea7\u578b\u548c\u65e9\u53d1\u578b\u5b50\u75eb\u524d\u671f\u9884\u6d4b\u7684\u6a21\u578b\uff0c\u4e3a\u4e34\u5e8a\u5b50\u75eb\u524d\u671f\u7684\u9884\u9632\u63d0\u4f9b\u4e86\u5e0c\u671b\u3002<\/p>\n<p>\u53c2\u8003\u4fe1\u606f&gt;&gt;https:\/\/www.sciencedirect.com\/science\/article\/pii\/S000293782300323X?utm_campaign=STMJ_AUTH_SERV_PUBLISHED&amp;utm_medium=email&amp;utm_acid=187076811&amp;SIS_ID=&amp;dgcid=STMJ_AUTH_SERV_PUBLISHED&amp;CMX_ID=&amp;utm_in=DM374553&amp;utm_source=AC_<\/p>\n<p>&nbsp;<\/p>\n<p>\u2756\u00a0\u5f20\u950b\u56e2\u961f\u57fa\u4e8e\u7ec6\u83cc\u6ce8\u5c04\u7cfb\u7edf\u53d1\u660e\u5168\u65b0\u86cb\u767d\u5b9a\u5411\u9012\u9001\u7cfb\u7edf<\/p>\n<p>\u8fd1\u65e5\uff0c\u535a\u5fb7\u7814\u7a76\u6240\u5f20\u950b\u56e2\u961f\u5728\u300a\u81ea\u7136\u300b\u6742\u5fd7\u53d1\u8868\u65b0\u6210\u679c\uff0c\u7814\u7a76\u8005\u4eec\u4ece\u5fae\u751f\u7269\u53d6\u6750\uff0c\u5236\u9020\u51fa\u4e86\u5168\u65b0\u7684\u86cb\u767d\u9012\u9001\u7cfb\u7edf\u3002\u8be5\u7cfb\u7edf\u5f62\u4f3c\u201c\u6ce8\u5c04\u5668\u201d\uff0c\u53ef\u4ee5\u901a\u8fc7\u6539\u53d8\u7ed3\u5408\u57fa\u56e2\u4ee5\u63a5\u8fd1100%\u7684\u6548\u7387\u9776\u5411\u7279\u5b9a\u7ec6\u80de\uff0c\u9012\u9001Cas9\u86cb\u767d\u7b49\u57fa\u56e0\u7f16\u8f91\u7ec4\u4ef6\u6216\u751f\u7269\u6bd2\u7d20\uff0c\u4ee5\u5b9e\u73b0\u57fa\u56e0\u7f16\u8f91\u3001\u8c03\u63a7\u7279\u5b9a\u751f\u7406\u8fc7\u7a0b\u4e43\u81f3\u6740\u6b7b\u764c\u7ec6\u80de\u7b49\u76ee\u7684\u3002<\/p>\n<div>\u53c2\u8003\u4fe1\u606f&gt;&gt;https:\/\/doi.org\/10.1038\/s41586-023-05870-7<\/div>\n<div>\u00a0<\/div>\n<div 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style=\"text-align: center;\">\u597d\u4f1a\u8bae<\/div>\n<div>\u2756 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