![\"RmFicvQBAkgBJ4sibF985CB53GqXpdUXJY1ibXic4tk7cicKMPtgyMRqWYUopq6yOghicWK3LOe3qL8V3Rjia4kHVKgsA\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgBJ4sibF985CB53GqXpdUXJY1ibXic4tk7cicKMPtgyMRqWYUopq6yOghicWK3LOe3qL8V3Rjia4kHVKgsA.jpeg\")
<\/figure><\/div>\n\n<\/p>\n2023\u5e749\u670829\u65e5\uff0c\u54c8\u5c14\u6ee8\u5de5\u4e1a\u5927\u5b66\u738b\u4e9a\u4e1c\u56e2\u961f\u8054\u5408\u4e2d\u56fd\u519c\u79d1\u9662\u97e9\u5929\u5bcc\u56e2\u961f\u5728bioRxiv\u53d1\u8868\u4e86\u9898\u4e3a\u201cA telomere-to-telomere genome assembly of Zhonghuang 13, a widely-grown soybean variety from the original center of Glycine max\u201d\u7684\u7814\u7a76\u6587\u7ae0\u3002\u7814\u7a76\u56e2\u961f\u9996\u6b21\u5bf9\u4e2d\u56fd\u5927\u8c46\u54c1\u79cd\u201c\u4e2d\u9ec413\u201d\uff08ZH13\uff09\u57fa\u56e0\u7ec4\u8fdb\u884c\u4e86\u7aef\u7c92\u5230\u7aef\u7c92\uff08T2T\uff09\u7ec4\u88c5\uff0c\u586b\u8865\u4e86\u5168\u90e8393\u4e2a\u7a7a\u767d\u533a\u57df\uff0c\u5f97\u5230\u4e86\u9996\u4e2a\u65e0\u95f4\u9699\u7684\u4e2d\u56fd\u5927\u8c46\u54c1\u79cdT2T\u57fa\u56e0\u7ec4\uff08ZH13-T2T\uff09\u3002<\/div>\n
\u4e00\u3001\u7814\u7a76\u80cc\u666f<\/p>\n
\u5927\u8c46\u662f\u4e16\u754c\u4e0a\u91cd\u8981\u7684\u6cb9\u6599\u548c\u86cb\u767d\u8d28\u4f5c\u7269\u4e4b\u4e00\uff0c\u4e3a\u98df\u54c1\u548c\u52a8\u7269\u9972\u6599\u63d0\u4f9b\u4e86\u8d85\u8fc7\u56db\u5206\u4e4b\u4e00\u7684\u86cb\u767d\u8d28\u3002\u5927\u8c46\u539f\u4ea7\u4e8e\u4e2d\u56fd\uff0c\u7814\u7a76\u8d77\u6e90\u5730\u533a\u7684\u9057\u4f20\u8d44\u6e90\u5bf9\u63a8\u52a8\u5168\u7403\u5927\u8c46\u80b2\u79cd\u5de5\u4f5c\u7684\u53d1\u5c55\u5177\u6709\u91cd\u5927\u610f\u4e49\u3002<\/div>\n
\u201c\u4e2d\u9ec413\u201d\u662f\u4e2d\u56fd\u80b2\u79cd\u5bb6\u4e8e2001\u5e74\u7cbe\u5fc3\u9009\u80b2\u7684\u5927\u8c46\u54c1\u79cd\uff0c\u9002\u5e94\u6027\u5e7f\u4e14\u5177\u6709\u4f18\u826f\u7684\u519c\u827a\u6027\u72b6\uff0c\u662f\u4e2d\u56fd21\u4e16\u7eaa\u524d\u4e8c\u5341\u5e74\u63a8\u5e7f\u9762\u79ef\u6700\u5927\u7684\u54c1\u79cd\u3002\u4e0e\u7f8e\u56fd\u201cWilliams 82\u201d\u76f8\u6bd4\uff0c\u4e2d\u56fd\u201c\u4e2d\u9ec413\u201d\u5177\u6709\u66f4\u9ad8\u7684\u9057\u4f20\u591a\u6837\u6027\u3002<\/div>\n
\u6b64\u524d\uff0c\u4e3a\u4e86\u8bc6\u522b\u4e0e\u6709\u5229\u6027\u72b6\u76f8\u5173\u7684\u5173\u952e\u57fa\u56e0\u548c\u9057\u4f20\u53d8\u5f02\uff0c\u79d1\u5b66\u5bb6\u5df2\u7ecf\u5bf9\u201c\u4e2d\u9ec413\u201d\u8fdb\u884c\u4e86\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u5de5\u4f5c\u3002\u7531\u4e8e\u65e2\u5f80\u6d4b\u5e8f\u6280\u672f\u5728\u7247\u6bb5\u957f\u5ea6\u65b9\u9762\u7684\u56fa\u6709\u5c40\u9650\u6027\uff0c\u73b0\u6709\u5927\u8c46\u53c2\u8003\u57fa\u56e0\u7ec4\u4ecd\u6709\u6570\u767e\u4e2a\u95f4\u9699\uff08gap\uff09\uff0c\u4e14\u7aef\u7c92\u548c\u7740\u4e1d\u7c92\u7b49\u9ad8\u5ea6\u91cd\u590d\u7684\u57fa\u56e0\u7ec4\u533a\u57df\u96be\u4ee5\u7cbe\u786e\u7ec4\u88c5\u548c\u6ce8\u91ca\uff0c\u5bfc\u81f4\u5927\u8c46\u57fa\u56e0\u7ec4\u7814\u7a76\u9762\u4e34\u4e00\u5b9a\u7684\u74f6\u9888\u3002<\/div>\n<\/p>\n
\n\n
\n![\"0?wx_fmt=png\"\/](\"https:\/\/mmbiz.qpic.cn\/mmbiz_png\/RmFicvQBAkgDyicHwmbEzzo5sic2tfURLb8VHg91gVXzcHrb0s2MSEh0oJks6WDpSMZUaXqXwZicX7V0t5skyCesQg\/0?wx_fmt=png\")
<\/figure><\/div>\n\n
\u56fe\uff1a\u6587\u7ae0\u5728bioRxiv\u4e0a\u7684\u9884\u5370\u7248\uff08\u6765\u6e90\/paper\uff09<\/p>\n
2023\u5e749\u670829\u65e5\uff0c\u54c8\u5c14\u6ee8\u5de5\u4e1a\u5927\u5b66\u738b\u4e9a\u4e1c\u56e2\u961f\u8054\u5408\u4e2d\u56fd\u519c\u79d1\u9662\u97e9\u5929\u5bcc\u56e2\u961f\u5728bioRxiv\u53d1\u8868\u4e86\u9898\u4e3a\u201cA telomere-to-telomere genome assembly of Zhonghuang 13, a widely-grown soybean variety from the original center of Glycine max\u201d\u7684\u7814\u7a76\u6587\u7ae0\u3002<\/div>\n
\u7814\u7a76\u56e2\u961f\u9996\u6b21\u5bf9\u4e2d\u56fd\u5927\u8c46\u54c1\u79cd\u201c\u4e2d\u9ec413\u201d\uff08ZH13\uff09\u57fa\u56e0\u7ec4\u8fdb\u884c\u4e86\u7aef\u7c92\u5230\u7aef\u7c92\uff08T2T\uff09\u7ec4\u88c5\uff0c\u586b\u8865\u4e86\u5168\u90e8393\u4e2a\u7a7a\u767d\u533a\u57df\uff0c\u5f97\u5230\u4e86\u9996\u4e2a\u65e0\u95f4\u9699\u7684\u4e2d\u56fd\u5927\u8c46\u54c1\u79cdT2T\u57fa\u56e0\u7ec4\uff08ZH13-T2T\uff09\u3002\u76f8\u5bf9\u4e4b\u524d\u7684\u4e2d\u9ec413\u57fa\u56e0\u7ec4\uff0c\u7814\u7a76\u4eba\u5458\u901a\u8fc7\u5206\u6790\u548c\u6ce8\u91ca\u53d1\u73b0\u4e86\u5927\u91cf\u5dee\u5f02\u5e8f\u5217\u3001\u7ed3\u6784\u53d8\u5f02\u3001\u91cd\u590d\u5e8f\u5217\u53ca\u5177\u6709\u9ad8\u7f6e\u4fe1\u5ea6\u7684\u65b0\u7f16\u7801\u57fa\u56e0\u3002ZH13-T2T\u57fa\u56e0\u7ec4\u7684\u7ec4\u88c5\u4ee3\u8868\u4e86\u5927\u8c46\u57fa\u56e0\u7ec4\u5b66\u7684\u91cd\u5927\u8fdb\u6b65\uff0c\u4e3a\u672a\u6765\u5927\u8c46\u5206\u5b50\u80b2\u79cd\u751f\u7269\u5b66\u7814\u7a76\u548c\u5b9e\u8df5\u63d0\u4f9b\u4e86\u5b9d\u8d35\u8d44\u6e90\u3002<\/div>\n
\u4e8c\u3001\u201c\u4e2d\u9ec413\u201d\u57fa\u56e0\u7ec4T2T\u62fc\u63a5\u7ec4\u88c5<\/p>\n
\u7814\u7a76\u4eba\u5458\u5bf9\u4e2d\u9ec413\u6837\u672c\u8fdb\u884c\u4e86\u4e8c\u3001\u4e09\u4ee3\u6df7\u5408\u6d4b\u5e8f\uff0c\u5171\u4ea7\u751f\u4e86\u56db\u7c7b\u6d4b\u5e8f\u6570\u636e\uff0c\u5305\u62ecPacBio Hifi\u6d4b\u5e8f\uff08\u6570\u636e\u91cf\uff1a96.89 Gbp\uff09\u3001ONT\u8d85\u957f\u6d4b\u5e8f\uff08\u6570\u636e\u91cf\uff1a96.63 Gbp\uff09\uff0cIllumina\u5168\u57fa\u56e0\u7ec4\u6d4b\u5e8f\uff08\u6570\u636e\u91cf\uff1a55.40Gbp\uff09\u548cIllumina Hi-C\u6d4b\u5e8f\uff08\u6570\u636e\u91cf\uff1a106.4 Gbp\uff09\u3002<\/div>\n
\u901a\u8fc7\u8fd9\u4e9b\u6d4b\u5e8f\u6570\u636e\uff0c\u7814\u7a76\u4eba\u5458\u4f7f\u7528\u4e00\u79cd\u7efc\u5408\u591a\u79cd\u62fc\u63a5\u7b97\u6cd5\u7684\u81ea\u7814\u62fc\u63a5\u5de5\u4f5c\u6d41\u8fdb\u884c\u4e86\u521d\u6b65\u62fc\u63a5\u3002\u5e76\u5728\u6b64\u57fa\u7840\u4e0a\uff0c\u8fdb\u4e00\u6b65\u901a\u8fc7\u81ea\u7814\u7b97\u6cd5\u8fdb\u884c\u6d4b\u5e8f\u7247\u6bb5\u91cd\u6bd4\u5bf9\u548c\u7edf\u8ba1\uff0c\u53d1\u73b0\u62fc\u63a5\u7ed3\u679c\u4e2d\u7684\u5b58\u5728\u7684gap\u533a\u57df\u548c\u6f5c\u5728\u9519\u62fc\u533a\u57df\uff0c\u5e76\u5229\u7528\u4e00\u79cd\u81ea\u7814\u8fed\u4ee3\u5f0f\u5c40\u90e8\u62fc\u63a5\u65b9\u6cd5\u8fdb\u884c\u5c40\u90e8\u62fc\u63a5\uff0c\u5b9e\u73b0\u4e86\u65e0gap\u7684\u7aef\u7c92\u5230\u7aef\u7c92\uff08T2T\uff09\u62fc\u63a5\u3002\u6700\u7ec8\uff0c\u62fc\u63a5\u4ea7\u751f\u7684\u4e2d\u9ec413 T2T\u57fa\u56e0\u7ec4\u957f\u5ea6\u4e3a1,015,024,879 bp\uff0cN50\u957f\u5ea6\u4e3a52,033,905 bp\u3002<\/div>\n\n
\n![\"RmFicvQBAkgDyicHwmbEzzo5sic2tfURLb8bHYJqrnpYXxrYEgGaibIb8qm1enCaicPIWoia99yWZNwQaibibGs5fMBIbg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDyicHwmbEzzo5sic2tfURLb8bHYJqrnpYXxrYEgGaibIb8qm1enCaicPIWoia99yWZNwQaibibGs5fMBIbg.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe1\uff1a\u4e2d\u9ec413 T2T\u57fa\u56e0\u7ec4\u4e0e\u73b0\u6709\u4e2d\u9ec413\u53c2\u8003\u57fa\u56e0\u7ec4\u548cWm82 T2T\u57fa\u56e0\u7ec4\u7684\u6bd4\u8f83\uff08\u6765\u6e90\/paper\uff09<\/p>\n
\u7814\u7a76\u4eba\u5458\u5bf9\u4ea7\u751f\u7684\u4e2d\u9ec413 T2T\u57fa\u56e0\u7ec4\u8fdb\u884c\u4e86\u591a\u65b9\u9762\u8d28\u91cf\u8bc4\u4f30\u3002\u5176\u4e2d\uff0c\u524d\u5e8f\u7248\u672c\u7684\u4e2d\u9ec413\u53c2\u8003\u57fa\u56e0\u7ec4\u4e2d\u5b58\u5728\u7684393\u4e2agap\u88ab\u5168\u90e8\u6210\u529f\u586b\u8865\uff1b20\u4e2a\u67d3\u8272\u4f53\u4e2d\u7684\u5168\u90e840\u4e2a\u7aef\u7c92\u533a\u57df\u5747\u6210\u529f\u62fc\u63a5\u5b8c\u6210\uff0c\u7aef\u7c92\u4e2d\u4f4d\u6570\u957f\u5ea6\u8fbe\u52308449 bp\uff1b\u65b0\u7248\u4e2d\u9ec413 T2T\u57fa\u56e0\u7ec4\u7684BUSCO\u6307\u6807\u8fbe\u523099.8%\uff0c\u78b1\u57fa\u8d28\u91cf\u8bc4\u5206\uff08Merqury\u8d28\u91cf\u8bc4\u5206\uff09\u8fbe\u523046.441\uff0c\u540c\u65f6PacBio Hifi\u548cONT\u8d85\u957f\u6d4b\u5e8f\u6570\u636e\u5728\u5168\u57fa\u56e0\u7ec4\u4e0a\u7684\u8986\u76d6\u5ea6\u5747\u5300\u4e14\u7b26\u5408\u671f\u671b\u503c\uff0c\u672a\u53d1\u73b0\u8986\u76d6\u5ea6\u5f02\u5e38\u533a\u57df\uff0c\u663e\u793a\u6574\u4e2a\u57fa\u56e0\u7ec4\u5177\u6709\u8f83\u9ad8\u7684\u62fc\u63a5\u8d28\u91cf\uff0c\u5e76\u53ef\u80fd\u4e0d\u5b58\u5728\u663e\u8457\u9519\u62fc\u3002<\/div>\n
\u7814\u7a76\u4eba\u5458\u8fdb\u4e00\u6b65\u5c06\u4e2d\u9ec413 T2T\u57fa\u56e0\u7ec4\u4e0e\u524d\u5e8f\u7248\u672c\u7684\u4e2d\u9ec413\u57fa\u56e0\u7ec4\u548c\u5357\u4eac\u519c\u4e1a\u5927\u5b66\u65b0\u8fd1\u53d1\u8868\u7684Williams 82\uff08Wm82\uff09T2T\u57fa\u56e0\u7ec4\u8fdb\u884c\u4e86\u6bd4\u8f83\uff08\u56fe 1\uff09\u3002\u76f8\u5bf9\u4e8e\u524d\u5e8f\u7248\u672c\u7684\u4e2d\u9ec413\u57fa\u56e0\u7ec4\uff0c\u672c\u7814\u7a76\u4ea7\u751f\u7684\u4e2d\u9ec413 T2T\u57fa\u56e0\u7ec4\u4e0e\u4e4b\u5171\u6709421\u4e2a\u957f\u5ea6\u8d85\u8fc75Kbp\u7684\u663e\u8457\u5e8f\u5217\u5dee\u5f02\u533a\u57df\uff08\u603b\u957f16.3 Mbp\uff09\u53ca112\u4e2a\u7ed3\u6784\u53d8\u5f02\uff0c\u5305\u62ec30\u4e2a\u5012\u7f6e\u53d8\u5f02\u300115\u4e2a\u6613\u4f4d\u53d8\u5f02\u300167\u4e2a\u5e8f\u5217\u91cd\u590d\u53d8\u5f02\u3002\u540c\u65f6\uff0c\u4e0eWm82 T2T\u57fa\u56e0\u7ec4\u6bd4\u8f83\uff0c\u4e2d\u9ec413 T2T\u57fa\u56e0\u7ec4\u53d1\u73b0\u4e86162\u4e2a\u957f\u5ea6\u8d85\u8fc75Kbp\u7684\u663e\u8457\u5e8f\u5217\u5dee\u5f02\u533a\u57df\uff08\u603b\u957f23.02 Mbp\uff09\u548c30\u4e2a\u7ed3\u6784\u53d8\u5f02\uff08\u5305\u62ec16\u4e2a\u5012\u7f6e\u53d8\u5f02\u30017\u4e2a\u6613\u4f4d\u53d8\u5f02\u30017\u4e2a\u5e8f\u5217\u91cd\u590d\u53d8\u5f02\uff09\u3002<\/div>\n
\u4e09\u3001\u57fa\u56e0\u7ec4\u6ce8\u91ca\u548c\u57fa\u56e0\u9884\u6d4b<\/p>\n
\u5927\u7ea657.07%\u7684\u5927\u8c46\u57fa\u56e0\u7ec4\u7531\u6ce8\u91ca\u7684\u91cd\u590d\u5143\u4ef6\u7ec4\u6210\u3002\u5728\u8fd9\u4e9b\u5143\u4ef6\u4e2d\uff0c\u53cd\u8f6c\u5f55\u8f6c\u5ea7\u5b50\u536038.16%\uff08\u5305\u62ec0.12%\u7684SINEs\u30011.58%\u7684LINEs\u548c36.47%\u7684LTR\u5143\u4ef6\uff09\uff0c\u800cDNA\u8f6c\u5ea7\u5b50\u53606.72%\uff08\u56fe2\uff09\u3002\u6b64\u5916\uff0c\u7814\u7a76\u4eba\u5458\u68c0\u6d4b\u52303.64 Mb\u7684\u5fae\u578b\u536b\u661f\uff0c11.58 Mb\u7684\u5c0f\u536b\u661f\uff0c11.44 Mb\u7684\u536b\u661f\uff0c0.41 Mb\u76845S rDNA\u548c4.16 Mb\u768448S rDNA\u5e8f\u5217\u3002\u8fd9\u4e9b\u4e32\u8054\u91cd\u590d\u5e8f\u5217\u5360\u5927\u8c46\u57fa\u56e0\u7ec4\u76842.63%\uff0826.65 Mb\uff09\uff0c\u660e\u663e\u8d85\u8fc7\u4e86\u5728\u4e2d\u9ec413\u53c2\u8003\u57fa\u56e0\u7ec4\u5e8f\u5217\u4e2d\u89c2\u5bdf\u5230\u76841.03%\uff0810.54Mb\uff09\u3002<\/div>\n\n
\n![\"RmFicvQBAkgDyicHwmbEzzo5sic2tfURLb8usTmyh2DicTwpiadkH6iakhFdnxwYqHr1H6aiadmlPZFHeJdhbzYvb2VMw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDyicHwmbEzzo5sic2tfURLb8usTmyh2DicTwpiadkH6iakhFdnxwYqHr1H6aiadmlPZFHeJdhbzYvb2VMw.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe2\uff1aTE \u5728 ZH13-T2T \u57fa\u56e0\u7ec4\u4e2d\u7684\u5206\u5e03\uff08\u6765\u6e90\/paper\uff09<\/p>\n
\u5bf9ZH13-T2T\u57fa\u56e0\u7ec4\u8fdb\u884c\u4ece\u5934\u6ce8\u91ca\uff0c\u5171\u83b7\u5f9750,564\u4e2a\u9ad8\u7f6e\u4fe1\u5ea6\u86cb\u767d\u8d28\u7f16\u7801\u57fa\u56e0\u3002\u4e0eZH13-2019\u76f8\u6bd4\uff0c\u7814\u7a76\u4eba\u5458\u5728gap\u533a\u57df\u5185\u53d1\u73b0\u4e86707\u4e2a\u65b0\u57fa\u56e0\u3002\u5728\u6b64\u524d\u7684gap\u533a\u57df\u4e2d\uff0c\u7814\u7a76\u4eba\u5458\u5728CM010421. C1\u67d3\u8272\u4f53\u768414.84-17.73Mb\u533a\u57df\u5185\u89c2\u5bdf\u5230\u65b0\u53d1\u73b0\u7684\u57fa\u56e0\u6570\u91cf\u6700\u591a\uff0c\u5171135\u4e2a\u65b0\u57fa\u56e0\u3002\u6b64\u5916\uff0c\u5728\u8fd9\u4e9bgap\u533a\u57df\u5185\u786e\u5b9a\u4e8642,668\u4e2aTEs\uff0c300\u4e2aGmCent-1\u5143\u7d20\u548c586\u4e2aGmCent-2\u5143\u7d20\u3002<\/div>\n
\u00a0<\/div>\n
\u56db\u3001\u67d3\u8272\u4f53\u7740\u4e1d\u7c92\u9274\u5b9a<\/p>\n
\u7814\u7a76\u4eba\u5458\u4f7f\u7528\u4e86\u4e32\u8054\u91cd\u590d\u67e5\u627e\u5de5\u5177\uff08TRF\uff09\u9274\u5b9aZH13-T2T\u57fa\u56e0\u7ec4\u4e2d\u53ef\u80fd\u6784\u6210\u7740\u4e1d\u7c92\u7684\u91cd\u590d\u5355\u4f53\u3002\u4e0e\u4e4b\u524d\u7684\u7814\u7a76\u4e00\u81f4\uff0c\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u957f\u5ea6\u4e3a91\u548c92bp\u7684\u5927\u91cf\u4e32\u8054\u91cd\u590d\u5e8f\u5217\uff0c\u4e0e\u7740\u4e1d\u7c92\u533a\u57dfTE\u7684\u95f4\u9699\u76f8\u543b\u5408\uff08\u56fe3\uff09\u300220\u4e2a\u7740\u4e1d\u7c92\u7684\u5e73\u5747\u957f\u5ea6\u4e3a2.40 Mb\uff0c\u5728CM010410.C1\u67d3\u8272\u4f53\u4e0a\u89c2\u5bdf\u5230\u7684\u6700\u957f\u7740\u4e1d\u7c92\uff084.42 Mb\uff09 \u548c\u5728CM010421.C1\u67d3\u8272\u4f53\u4e0a\u89c2\u5bdf\u5230\u6700\u77ed\u7684\u7740\u4e1d\u7c92\uff080.66 Mb\uff09\u3002<\/div>\n
\u00a0<\/div>\n
\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u7740\u4e1d\u7c92\u957f\u5ea6\u4e0e\u67d3\u8272\u4f53\u5927\u5c0f\u4e4b\u95f4\u6ca1\u6709\u663e\u8457\u76f8\u5173\u6027\u3002\u6b64\u5916\uff0c\u7740\u4e1d\u7c92\u7684\u76f8\u5bf9\u4f4d\u7f6e\u5728\u4e0d\u540c\u67d3\u8272\u4f53\u4e4b\u95f4\u5b58\u5728\u5dee\u5f02\uff0c\u6700\u5c0fL\/S\u6bd4\uff08\u957f\u81c2\u957f\/\u77ed\u81c2\u957f\uff09\u4e3a1.02\uff08CM010415.C1\uff09\uff0c\u6700\u5927L\/S\u6bd4\u4e3a2.95\uff08CM010423.C1\uff09\u3002\u5728\u5927\u8c46T2T\u57fa\u56e0\u7ec4\u7684\u7740\u4e1d\u7c92\u533a\u5171\u9274\u5b9a\u51fa8\u4e2a\u57fa\u56e0\u3002\u8fd9\u4e9b\u57fa\u56e0\u4e3b\u8981\u5bcc\u96c6\u67d3\u8272\u8d28DNA\u7ed3\u5408\u3001mRNA\u987a\u5f0f\u526a\u63a5\u3001\u7ec4\u86cb\u767d\u7ed3\u5408\u3001\u57fa\u5e95\u8f6c\u5f55\u56e0\u5b50\u3001\u526a\u63a5\u4f53\u548c\u5627\u5576\u4ee3\u8c22\uff08\u56fe3\uff09\u3002<\/div>\n
\u00a0<\/div>\n
\u5e73\u5747\u800c\u8a00\uff0c\u7740\u4e1d\u7c92\u5e8f\u5217\u753196.0%\u7684\u7740\u4e1d\u7c92\u536b\u661fDNA\uff08CentC\uff09\u3001\u7740\u4e1d\u7c92\u53cd\u8f6c\u5f55\u8f6c\u5ea7\u5b50\uff08CRM\uff09\u548c\u5176\u4ed6\u975eCRM Gypsy\u53cd\u8f6c\u5f55\u8f6c\u5ea7\u5b50\u7ec4\u6210\u3002\u8fd9\u4e9b\u6210\u5206\u7684\u6bd4\u4f8b\u5728\u4e0d\u540c\u7684\u7740\u4e1d\u7c92\u4e2d\u5dee\u5f02\u5f88\u5927\uff0cGmCent-1\u4ece0.0%\u523073.3%\uff0cGmCent-2\u4ece0.0%\u523090.4%\uff0cCRM\u4ece0.0%\u52302.2%\uff0c\u5176\u4ed6\u975eCRM Gypsy\u53cd\u8f6c\u5ea7\u5b50\u4ece7.3%\u523068.2%\u4e0d\u7b49\u3002\u51e0\u4e4e\u6240\u6709\u7684\u7740\u4e1d\u7c92\u90fd\u5bcc\u542b CentC\u3002<\/div>\n
<\/p>\n\n
\n![\"RmFicvQBAkgDyicHwmbEzzo5sic2tfURLb8XNdFOYkscg0xuz4CCRianBdROuuCnLpDeFrqzgZ87gCriapkYO2iawTJg\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgDyicHwmbEzzo5sic2tfURLb8XNdFOYkscg0xuz4CCRianBdROuuCnLpDeFrqzgZ87gCriapkYO2iawTJg.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe3\uff1a\u7aef\u7c92\u548c\u7740\u4e1d\u7c92\u7684\u57fa\u56e0\u7ec4\u7ed3\u6784\uff08\u6765\u6e90\/paper\uff09<\/p>\n
\u4e94\u3001\u7814\u7a76\u610f\u4e49<\/p>\n
\u8be5\u9879\u7814\u7a76\u662f\u4e2d\u56fd\u5927\u8c46\u54c1\u79cd\u7684\u9996\u4e2aT2T\u57fa\u56e0\u7ec4\u7ec4\u88c5\u3002T2T\u57fa\u56e0\u7ec4\u63d0\u4f9b\u4e86\u65e0\u95f4\u9699\u7684\u53c2\u8003\u57fa\u56e0\u7ec4\uff0c\u4e5f\u4e3a\u5168\u9762\u89e3\u7801\u548c\u6df1\u5165\u4e86\u89e3\u5927\u8c46\u57fa\u56e0\u7ec4\u4e2d\u7684\u590d\u6742\u91cd\u590d\u63d0\u4f9b\u4e86\u65b0\u7684\u673a\u4f1a\uff0c\u8fd9\u5bf9\u4e8e\u690d\u7269\u57fa\u56e0\u7ec4\u5b66\u7814\u7a76\u5177\u6709\u91cd\u8981\u7684\u4ef7\u503c\u3002<\/div>\n
\u00a0<\/div>\n
\u5927\u8c46\u662f\u4e00\u79cd\u5178\u578b\u7684\u77ed\u65e5\u4f5c\u7269\uff0c\u5149\u6e29\u53cd\u5e94\u654f\u611f\u3002\u82b1\u671f\u548c\u751f\u80b2\u671f\u662f\u51b3\u5b9a\u5927\u8c46\u751f\u6001\u9002\u5e94\u6027\u7684\u6700\u4e3b\u8981\u56e0\u7d20\u3002\u4ee5\u5f80\u62a5\u9053\u4e86\u5927\u91cf\u7684\u82b1\u671f\u548c\u751f\u80b2\u671f\u6570\u91cf\u6027\u72b6\u57fa\u56e0\u5ea7\u548c\u663e\u8457\u5173\u8054\u4f4d\u70b9\uff0c\u4f46\u5728\u6316\u6398\u4e3b\u6548\u57fa\u56e0\u65f6\u5019\u9009\u533a\u57df\u5f80\u5f80\u8f83\u5927\uff0c\u5e76\u4e14\u5df2\u6709\u7684\u53c2\u8003\u57fa\u56e0\u7ec4\u5b58\u5728\u9057\u6f0f\u5019\u9009\u57fa\u56e0\u7684\u98ce\u9669\u3002\u6587\u7ae0\u5728T2T-ZH13\u53c2\u8003\u57fa\u56e0\u7ec4\u6ce8\u91ca\u63ed\u793a\u4e86\u5927\u91cf\u65b0\u57fa\u56e0\uff0c\u4e3a\u9ad8\u6548\u6316\u6398\u76ee\u6807\u519c\u827a\u6027\u72b6\u5019\u9009\u533a\u57df\u4e3b\u6548\u57fa\u56e0\u63d0\u4f9b\u4e86\u65b0\u7684\u5206\u5b50\u9776\u70b9\u3002\u4f5c\u4e3a\u6211\u56fd\u63a8\u5e7f\u9762\u79ef\u6700\u5927\u7684\u54c1\u79cd\u4e4b\u4e00\uff0cZH13-T2T\u57fa\u56e0\u7ec4\u5c06\u4e3a\u4eca\u540e\u5927\u8c46\u5206\u5b50\u80b2\u79cd\u5de5\u4f5c\u63d0\u4f9b\u4e86\u5b9d\u8d35\u8d44\u6e90\u3002<\/div>\n
\u00a0<\/div>\n
\u3010\u58f0\u660e\u3011\u4e3a\u4e86\u63a8\u52a8\u57fa\u56e0\u53ca\u6570\u5b57\u751f\u547d\u5065\u5eb7\u79d1\u6280\u63a8\u5e7f\u3001\u4ea7\u4e1a\u53d1\u5c55\u53ca\u653f\u4ea7\u5b66\u7814\u7528\u8fde\u63a5\uff0c\u57fa\u56e0\u6167\u79c9\u6301\u4e13\u4e1a\u3001\u8d4b\u80fd\u3001\u4e2d\u7acb\u7684\u7acb\u573a\u6536\u96c6\u3001\u5206\u6790\u53ca\u53d1\u5e03\u76f8\u5173\u4fe1\u606f\u3002\u4f46\u7531\u4e8e\u65f6\u6548\u6027\u53ca\u884c\u4e1a\u7279\u6b8a\u6027\uff0c\u6240\u520a\u767b\u5185\u5bb9\u4ec5\u4f9b\u7814\u7a76\u53c2\u8003\uff0c\u672a\u7ecf\u8bf4\u660e\u4e0d\u4f5c\u4e3a\u51b3\u7b56\u4f9d\u636e\uff1b\u672c\u6587\u76f8\u5173\u4fe1\u606f\u4e0d\u4ee3\u8868\u57fa\u56e0\u6167\u7684\u89c2\u70b9\uff1b\u57fa\u56e0\u6167\u5e73\u53f0\u520a\u767b\u7684\u539f\u521b\u5185\u5bb9\u7684\u77e5\u8bc6\u4ea7\u6743\u4e3a\u201c\u57fa\u56e0\u6167\u201d\u5546\u6807\u62e5\u6709\u8005\u53ca\u76f8\u5173\u6743\u5229\u4eba\u6240\u6709\uff1b\u6b22\u8fce\u8f6c\u8f7d\uff0c\u8f6c\u8f7d\u8bf7\u7533\u8bf7\u5e76\u6ce8\u660e\u6765\u6e90\u3002\u6b22\u8fce\u4e2a\u4eba\u53ca\u673a\u6784\u6295\u7a3f\u53ca\u5408\u4f5c\u3002<\/div>\n\n
\n![\"640?wx_fmt=png\"\/](\"https:\/\/mmbiz.qpic.cn\/mmbiz_png\/RmFicvQBAkgA9s66XicYRZZ7lo9LkJk358PZbHu2C7lpjbgrc9a42pwfnLw8lygVIYNeYjtOrFsxnlAqOVn2V18A\/640?wx_fmt=png\")
<\/figure><\/div>\n\n
<\/a><\/div>\n
<\/p>\n\n
\n![\"RmFicvQBAkgATrWjpPIAhJWs5fhBPbW6RCThiaeBxsibobfibgZzZOqasvkwb8Z3sgTElJpAZu3u4waUY5ohXwo2Ow\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgATrWjpPIAhJWs5fhBPbW6RCThiaeBxsibobfibgZzZOqasvkwb8Z3sgTElJpAZu3u4waUY5ohXwo2Ow.png\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n<\/a><\/div>\n
<\/p>\n\n
\n![\"640?wx_fmt=png\"\/](\"https:\/\/mmbiz.qpic.cn\/mmbiz_png\/RmFicvQBAkgC62SMyPowMkjYYBrcbPqIqBicbRfqK5qu7mP6QYwlPeQpMEU4SubHdoQG6rjZ9UklicjnIkk3pZOBA\/640?wx_fmt=png\")
<\/figure><\/div>\n\n
\u5173\u4e8e\u57fa\u56e0\u6167>><\/p>\n
\u57fa\u56e0\u6167\u54c1\u724c\u521b\u7acb\u4e8e2015\u5e74\uff0c\u4e13\u6ce8\u6570\u5b57\u751f\u547d\u5065\u5eb7\u4ea7\u4e1a\u77e5\u8bc6\u670d\u52a1\u3002\u521b\u59cb\u56e2\u961f\u6df1\u8015\u884c\u4e1a\u4e00\u7ebf10\u4f59\u5e74\uff0c\u57fa\u4e8e\u667a\u5e93\u3001\u4f01\u4e1a\u5e93\u548c\u77e5\u8bc6\u5e93\uff0c\u63d0\u4f9b\u4ea7\u4e1a\u89c4\u5212\u3001\u884c\u7814\u54a8\u8be2\u3001\u79d1\u6280\u63a8\u5e7f\u7b49\u670d\u52a1\u3002\u8fde\u7eed6\u5e74\u53d1\u5e03\u884c\u4e1a\u84dd\u76ae\u4e66\uff0c\u88ab\u56fd\u5bb6\u53ca\u7701\u5e02\u7ea7\u4ea7\u4e1a\u62a5\u544a\u6536\u5f55\uff0c\u534f\u52a9\u5b66\u4f1a\u4e13\u5bb6\u7ec4\u7ec7\u4ea7\u4e1a\u673a\u6784\u53d1\u5e03\u591a\u9879\u884c\u4e1a\u5171\u8bc6\uff0c\u63a8\u52a8\u751f\u547d\u79d1\u6280\u666e\u60e0\u548c\u4ea7\u4e1a\u521b\u65b0\u878d\u5408\u53d1\u5c55\u3002<\/div>\n
\u2606\u00a0\u56fd\u53d1\u6539\u300a\u6218\u7565\u6027\u65b0\u5174\u4ea7\u4e1a\u53d1\u5c55\u5c55\u671b\u300b\u767d\u76ae\u4e66\u6267\u7b14<\/div>\n
\u2606\u00a0\u8fde\u7eed\u516d\u5e74\u53d1\u5e03\u57fa\u56e0\u884c\u4e1a\u84dd\u76ae\u4e66<\/div>\n
\u2606\u00a0\u4e2d\u56fd\u6297\u764c\u534f\u4f1a\u80bf\u7624\u6807\u5fd7\u4e13\u4e1a\u59d4\u5458\u4f1a\u6218\u7565\u5408\u4f5c\u5355\u4f4d<\/div>\n
\u2606\u00a0\u4e2d\u56fd\u9057\u4f20\u5b66\u4f1a\u751f\u7269\u4ea7\u4e1a\u4fc3\u8fdb\u59d4\u5458\u4f1a\u59d4\u5458<\/div>\n
\u2606\u00a0\u5e7f\u4e1c\u7701\u7cbe\u51c6\u533b\u5b66\u5e94\u7528\u5b66\u4f1a\u653f\u7b56\u7814\u7a76\u5e94\u7528\u5206\u4f1a\u5e38\u59d4<\/div>\n
\u2606\u00a0\u6df1\u5733\u5e02\u5065\u5eb7\u4ea7\u4e1a\u53d1\u5c55\u4fc3\u8fdb\u4f1a\u526f\u4f1a\u957f\u5355\u4f4d<\/div>\n
\u2606 \u521b\u59cb\u4eba\u5165\u9009\u6df1\u5733\u5e02\u79d1\u6280\u4e13\u5bb6\u5e93\u4e13\u5bb6<\/div>\n
\u2606\u00a0\u53c2\u4e0e\u7ec4\u7ec7\u591a\u5bb6\u57fa\u56e0\u673a\u6784\u591a\u9879\u884c\u4e1a\u5171\u8bc6\u548c\u56e2\u4f53\u6807\u51c6<\/div>\n
\u2606\u00a0\u7ec4\u7ec7\u57fa\u56e0\u68c0\u6d4b\u8054\u76df\uff08\u7b79\uff09\u9996\u5c4a\u3001\u7b2c\u4e8c\u5c4a\u4f1a\u8bae<\/div>\n
\u2606\u00a0\u4e3b\u529e\u6570\u5b57\u5065\u5eb7\u79c1\u8463\u4f1a\u3001\u5927\u6e7e\u533a\u751f\u547d\u5065\u5eb7\u521b\u65b0\u8bba\u575b<\/div>\n
<\/p>","protected":false},"excerpt":{"rendered":"
2023\u5e749\u670829\u65e5\uff0c\u54c8\u5c14\u6ee8\u5de5\u4e1a\u5927\u5b66\u738b\u4e9a\u4e1c\u56e2\u961f\u8054\u5408 …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[996],"tags":[1486],"class_list":["post-7927","post","type-post","status-publish","format-standard","hentry","category-news","tag-1486"],"_links":{"self":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/7927","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/comments?post=7927"}],"version-history":[{"count":3,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/7927\/revisions"}],"predecessor-version":[{"id":13265,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/7927\/revisions\/13265"}],"wp:attachment":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/media?parent=7927"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/categories?post=7927"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/tags?post=7927"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}