{"id":11675,"date":"2016-11-30T08:16:55","date_gmt":"2016-11-30T00:16:55","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMzE4MzU3NA==&mid=504148143&idx=1&sn=949f785b4c02f185a45532691d7b7064&chksm=7371909644061980c50b25b4d622ea191c31960e8142c5202a1894fbe93bd55b36fb6d7f01c4#rd"},"modified":"2026-04-03T12:15:22","modified_gmt":"2026-04-03T04:15:22","slug":"494949","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2016\/11\/30\/494949\/","title":{"rendered":"GeneMail\uff1a\u7626\u57fa\u56e0\u3001\u518d\u751f\u533b\u5b66\u3001\u9996\u4e2a\u8fdb\u5165\u4e34\u5e8aPD-L1\u5355\u6297\u3001Celegne\u6295\u8d44\u673a\u5668\u5b66\u4e60"},"content":{"rendered":"

<\/p>\n

\u5173\u952e\u8bcd\uff1a\u7626\u57fa\u56e0\u3001\u518d\u751f\u533b\u5b66<\/a>\u3001\u9996\u4e2a\u8fdb\u5165\u4e34\u5e8a\u5f00\u53d1\u7684PD-L1\u5355\u6297<\/a>\uff1b\u745e\u5178\u5b66\u8005\u56de\u5e94\u201c\u96fe\u973e\u81f4\u4eba\u4f53\u6297\u836f\u201d\u4f20\u95fb\uff1bCelegne\u6295\u8d44\u673a\u5668\u5b66\u4e60<\/a>\uff08\u70b9\u51fb\u84dd\u8272\u5173\u952e\u8bcd\u53ef\u5ef6\u4f38\u9605\u8bfb\uff09<\/div>\n
\u9605\u8bfb\u7528\u65f6\uff1a2634\u5b57\uff0c\u7ea66\u5206\u949f<\/div>\n\n
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\"eicZhoGYCfyboyIeahsibN0sa4cH3y0LuqyUsVOcIFEYxKC8zy4ibEicqM7vnZPhBgxbT9ue5IK37A3taWRd4TPz2A\"\/<\/figure><\/div>\n\n<\/div>\n
\n\n
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\"eicZhoGYCfyboyIeahsibN0sa4cH3y0LuqhyNRV16OAx4lv4wiaBURZUa36ueqFEez68Zicy4NE1bjvRnaQtQdFV6A\"\/<\/figure><\/div>\n\n
\u4eca\u65e5\u5934\u6761<\/div>\n\n
\u5168\u7403\u9996\u4e2a\u53ef\u76ae\u4e0b\u6ce8\u5c04\u7684\u65b0\u4e00\u4ee3PD-L1\u5355\u6297\u901a\u8fc7\u7f8e\u56fdFDA\u5ba1\u8bc4\u83b7\u51c6\u8fdb\u5165\u4e34\u5e8a<\/div>\n
PD-L1\u5355\u6297\u901a\u8fc7FDA\u5ba1\u6838\u8fdb\u5165\u4e34\u5e8a<\/div>\n
\u601d\u8def\u8fea\u4eca\u65e5\u5ba3\u5e03\u516c\u53f8\u63d0\u4ea4\u7684\u65b0\u836f\u7814\u7a76\u7533\u8bf7(IND)\u5df2\u7ecf\u901a\u8fc7\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40(FDA)\u7684\u5ba1\u8bc4\uff0c\u83b7\u51c6\u5728\u7f8e\u56fd\u5f00\u5c55\u4e34\u5e8a\u7814\u7a76\u3002KN035\u662f\u601d\u8def\u8fea\u4e0e\u5eb7\u5b81\u6770\u745e\u8054\u5408\u5f00\u53d1\u7684\u7684\u65b0\u4e00\u4ee3\u7684PD-L1\u6297\u4f53\uff0c\u4e0e\u76ee\u524d\u5df2\u7ecf\u4e0a\u5e02\u548c\u5728\u7814\u7684PD1\/PDL1\u6297\u4f53\u6709\u660e\u663e\u5dee\u5f02\u5316\u3002KN035\u662f\u76ee\u524d\u5168\u7403\u552f\u4e00\u8fdb\u5165\u4e34\u5e8a\u5f00\u53d1\u9488\u5bf9\u80bf\u7624\u514d\u75ab\u6cbb\u7597\u7684\u5355\u57df\u6297\u4f53\uff0c\u5177\u6709\u53ef\u76ae\u4e0b\u6ce8\u5c04\uff0c\u5e38\u6e29\u4e0b\u7a33\u5b9a\u7b49\u4f18\u70b9\u3002<\/div>\n
\u53c2\u8003\uff1ahttp:\/\/www.3dmedcare.com\/aboutus\/xwzx\/index.html?url=\/2016\/news\/2016_11_29.html<\/div>\n
(Tips\uff1a\u76ee\u524d\u7248\u672c\uff0c\u9700\u590d\u5236\u94fe\u63a5\u5230\u6d4f\u89c8\u5668\u67e5\u770b\u539f\u6587\uff0c\u4e00\u5468\u5185\u6211\u4eec\u4f1a\u4f18\u5316\uff0c\u4f7f\u60a8\u70b9\u51fb\u76f4\u8fbe \u2708\ufe0f\uff09<\/div>\n
\u00a0<\/div>\n
\u653f\u7b56\u6307\u5357<\/div>\n\n<\/div>\n
<\/div>\n
\u7f8e\u56fd\u56fd\u4f1a\u59d4\u5458\u4f1a\u53d1\u5e03\u4e86\u4e8c\u5341\u4e00\u4e16\u7eaa\u533b\u836f\u6cd5\u6848\u7684\u6700\u7ec8\u8349\u6848<\/div>\n
\u56fd\u4f1a\u5ba3\u5e03\u6700\u7ec8\u533b\u836f\u8349\u6848<\/div>\n
\u7f8e\u56fd\u661f\u671f\u4e94\u65f6\u95f4\uff0c\u56fd\u4f1a\u536b\u751f\u59d4\u5458\u4f1a\u9886\u5bfc\u4eba\u516c\u5e03\u4e8c\u5341\u4e00\u4e16\u7eaa\u7684\u533b\u836f\u6cd5\u6700\u7ec8\u8349\u6848\uff0c\u7f8e\u56fd\u4f17\u8bae\u9662\u5c06\u5728\u661f\u671f\u4e09\u6295\u7968\u5168\u9762\u751f\u7269\u533b\u5b66\u62e8\u6b3e\u6cd5\u6848\u3002<\/div>\n
\u53c2\u8003\uff1ahttps:\/\/www.genomeweb.com\/policy-legislation\/congressional-committees-release-final-draft-21st-century-cures-act<\/div>\n
<\/div>\n
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\u79d1\u7814\u6280\u672f<\/div>\n
\n\n
\u6d1b\u514b\u83f2\u52d2\u5927\u5b66\u7814\u7a76\u516c\u56ed\u571f\u58e4\u7ec6\u83cc\u7684\u4ee3\u8c22\u7269\uff0c\u53d1\u73b0\u53ef\u80fd\u4e0e\u533b\u5b66\u76f8\u5173\u7684\u57fa\u56e0\u5e8f\u5217<\/div>\n
\u533b\u5b66\u76f8\u5173\u7684\u7ec6\u83cc\u57fa\u56e0<\/div>\n
\u6d1b\u514b\u83f2\u52d2\u5927\u5b66\u4e00\u4e2a\u9886\u5bfc\u7684\u5c0f\u7ec4\u5df2\u7ecf\u91c7\u7528\u7cfb\u7edf\u53d1\u80b2\u7684\u65b9\u6cd5\u6765\u786e\u5b9a\u7ebd\u7ea6\u516c\u56ed\u571f\u58e4\u7ec6\u83cc\u4ea7\u751f\u7684\u5929\u7136\u4ea7\u7269\uff0c\u53d1\u73b0\u4e86\u53ef\u80fd\u4e0e\u533b\u5b66\u6709\u5173\u7684\u7ec6\u83cc\u751f\u4ea7\u7684\u57fa\u56e0\u5e8f\u5217\u3002<\/div>\n
\u53c2\u8003\uff1ahttps:\/\/www.genomeweb.com\/sequencing\/metagenomics-hints-natural-product-potential-microbes-new-york-city-parks<\/div>\n
\u00a0<\/div>\n
VirusDetect \u2013 \u57fa\u4e8e\u5c0fRNA\u6570\u636e\u9274\u5b9a\u75c5\u6bd2\u7684\u65b0\u6d41\u7a0b<\/div>\n
\u5c0fRNA1\u75c5\u6bd2\u9274\u5b9a<\/div>\n
VirusDetect\u662f\u4e00\u4e2a\u514d\u8d39\u7684\u5f00\u6e90\u751f\u7269\u4fe1\u606f\u5b66\u5206\u6790\u6d41\u7a0b\uff0c\u53ef\u4ee5\u6709\u6548\u5730\u5206\u6790\u5c0fRNA\uff08sRNA\uff09\u6570\u636e\u96c6\uff0c\u4ee5\u8bc6\u522b\u5df2\u77e5\u548c\u65b0\u578b\u75c5\u6bd2\u3002 \u535a\u601d\u6c64\u666e\u68ee\u7814\u7a76\u6240\uff08BTI\uff09\u526f\u6559\u6388\u5f20\u519b\u98de\u548c\u540c\u4e8b\u5728\u6700\u8fd1\u7684\u4e00\u7bc7\u5173\u4e8e\u75c5\u6bd2\u5b66\u7684\u8bba\u6587\u4e2d\u4ecb\u7ecd\u4e86\u8fd9\u4e00\u6d41\u7a0b\u3002<\/div>\n
\u53c2\u8003\uff1ahttp:\/\/www.sciencedirect.com\/science\/article\/pii\/S0042682216303166<\/div>\n
\u5f00\u6e90\u8f6f\u4ef6\uff1ahttp:\/\/bti.cornell.edu\/news\/virusdetect-a-new-pipeline-for-virus-identification\/<\/div>\n
\u00a0<\/div>\n
\u6768\u68ee\u5236\u836f\u5411\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u63d0\u4ea4\u6cbb\u7597\u94f6\u5c51\u75c5\u65b0\u836fguselkumab\u7533\u8bf7<\/div>\n
\u94f6\u5c51\u75c5\u65b0\u836f<\/div>\n
\u6768\u68ee\u5df2\u5411\u7f8e\u56fd\u63d0\u4ea4\u6f5c\u5728\u6cbb\u7597\u94f6\u5c51\u75c5\u836f\u7269guselkumab\u7533\u8bf7\u3002\u7d27\u968f\u5176\u540e\uff0c\u76ee\u524d\u5411\u6b27\u6d32\u836f\u54c1\u7ba1\u7406\u5c40\u4e5f\u63d0\u4ea4\u4e86\u8be5\u836f\u7533\u8bf7\u3002Guselkumab\u836f\u7269\u662f\u9776\u5411\u86cb\u767d\u8d28\u767d\u4ecb\u7d20\uff08IL\uff09-23\u7684\u4eba\u5355\u514b\u9686\u6297\u4f53\uff0c\u5df2\u77e5\u8be5\u6297\u4f53\u5728\u514d\u75ab\u4ecb\u5bfc\u7684\u708e\u6027\u75be\u75c5\u7684\u53d1\u5c55\u4e2d\u8d77\u5173\u952e\u4f5c\u7528\u3002<\/div>\n
\u53c2\u8003\uff1ahttp:\/\/www.pharmatimes.com\/news\/janssen_brings_psoriasis_therapy_guselkumab_to_the_ema_1178945<\/div>\n
\u00a0<\/div>\n
\u745e\u5178\u5b66\u8005\u56de\u5e94\u201c\u96fe\u973e\u81f4\u4eba\u4f53\u6297\u836f\u201d\u4f20\u95fb\uff1a\u672a\u8bf4\u8fc7\u6b64\u8bdd<\/div>\n
\u6297\u751f\u7d20\u8010\u836f\u6027\u57fa\u56e0<\/div>\n
2016\u5e7411\u6708\uff0c\u5305\u62ec\u62c9\u5c14\u677e\u5728\u5185\u7684\u745e\u5178\u54e5\u5fb7\u5821\u5927\u5b66\u6297\u751f\u7d20\u8010\u836f\u6027\u7814\u7a76\u4e2d\u5fc34\u4f4d\u5b66\u8005\u5728\u300aMicrobiome\uff08\u5fae\u751f\u7269\uff09\u300b\u4e0a\u53d1\u8868\u4e86\u300a\u4eba\u3001\u52a8\u7269\u4e0e\u73af\u5883\u8010\u836f\u57fa\u56e0\u7ec4\u7684\u7ed3\u6784\u4e0e\u591a\u6837\u6027\u300b\uff0c\u6587\u4e2d\uff0c\u62c9\u5c14\u677e\u7684\u56e2\u961f\u8868\u793a\uff0c\u4ed6\u4eec\u4ece\u5317\u4eac\u4e00\u6b21\u96fe\u973e\u5929\u768414\u4efd\u7a7a\u6c14\u6837\u672c\u4e2d\u68c0\u6d4b\u51fa\u5927\u91cf\u6297\u751f\u7d20\u8010\u836f\u6027\u57fa\u56e0\u3002<\/div>\n
\u53c2\u8003\uff1ahttp:\/\/microbiomejournal.biomedcentral.com\/articles\/10.1186\/s40168-016-0199-5<\/div>\n
\u00a0<\/div>\n
OSKM\u57fa\u56e0\u7ec4\u5408\u53ef\u5c06\u6210\u4eba\u7ec6\u80de\u6062\u590d\u5230\u80da\u80ce\u6837\u72b6\u6001<\/div>\n
\u518d\u751f\u533b\u5b66<\/div>\n
\u7ec6\u80de\u91cd\u65b0\u7f16\u7a0b\u7684\u53d1\u73b0\u8005Shinya Yamanaka\u83b7\u5f97\u4e86\u8bfa\u8d1d\u5c14\u5956\uff0c\u6253\u5f00\u4e86\u518d\u751f\u533b\u5b66\u7684\u5927\u95e8\u3002\u8fd9\u79cd\u6280\u672f\u7684\u57fa\u7840\u4e0a\u5f15\u5165\u56db\u79cd\u88ab\u79f0\u4e3aoskm\uff08 OCT4, SOX2, KLF4, and MYC\u57fa\u56e0\u7684\u7f29\u5199\uff09\u7684\u57fa\u56e0\u7ec4\u5408\uff0c\u53ef\u5c06\u6210\u4eba\u7ec6\u80de\u6062\u590d\u5230\u80da\u80ce\u6837\u72b6\u6001\uff0c\u5c06\u5176\u8f6c\u5316\u4e3a\u591a\u80fd\u5e72\u7ec6\u80de\u3002<\/div>\n
\u53c2\u8003\uff1ahttp:\/\/www.genengnews.com\/gen-news-highlights\/another-wrinkle-found-for-cell-reprogramming-in-vivo\/81253468<\/div>\n
\u00a0<\/div>\n
\u201c\u7626\u57fa\u56e0\u201d FBN1<\/div>\n
\u7626\u57fa\u56e0<\/div>\n
Abby Solomon\u4ece\u5c0f\u60a3\u6709\u4e00\u79cd\u53ea\u6709\u5341\u4ebf\u5206\u4e4b\u4e00\u6982\u5ff5\u7684\u9057\u4f20\u7efc\u5408\u5f81\uff1a\u5403\u5b8c\u98df\u7269\u4e00\u5c0f\u65f6\u540e\u5f00\u59cb\uff0c5\u82f1\u5c3a10\u82f1\u5bf8\u9ad8\uff0c\u91cd99\u78c5\u3002\u73b0\u5728Abby Solomon21\u5c81\uff0c\u60a3\u6709\u65b0\u751f\u513f\u65e9\u8870\u75c7\uff08neonatal progeroid syndrome\uff09\uff0c\u7531\u4e8eFBN1\u57fa\u56e0\u7a81\u53d8\uff0c\u5bfc\u81f4\u9f3b\u5b50\u548c\u773c\u775b\u635f\u4f24\uff0c\u76ae\u80a4\u4e0b\u7684\u8102\u80aa\u5c42\u906d\u5230\u7834\u574f\uff0c\u4f7f\u5f97\u751a\u81f3\u9752\u5c11\u5e74\u770b\u8d77\u6765\u4e2d\u5e74\u3002 \u540c\u65f6\u5e72\u6270\u8eab\u4f53\u4ea7\u751f\u8c03\u8282\u8840\u7cd6\u7684\u6fc0\u7d20asprosin\u3002<\/div>\n
\u53c2\u8003\uff1ahttp:\/\/www.nytimes.com\/2016\/11\/25\/opinion\/sunday\/the-thin-gene.html?_r=0<\/div>\n
\u00a0<\/div>\n
\u53ef\u80fd\u4f1a\u5f71\u54cd\u4f60\u996e\u9152\u559c\u597d\u7684\u57fa\u56e0<\/div>\n
\u996e\u9152\u57fa\u56e0<\/div>\n
\u8fd9\u4e2a\u57fa\u56e0\u88ab\u79f0\u4e3abeta-Klotho\uff0c\u5b83\u53ef\u80fd\u8c03\u8282\u996e\u9152\u7684\u559c\u597d\u3002 \u7814\u7a76\u4eba\u5458\u53d1\u73b0\uff0c\u6539\u9020\u7f3a\u4e4f\u8fd9\u79cd\u57fa\u56e0\u7684\u5c0f\u9f20\u4f3c\u4e4e\u66f4\u559c\u6b22\u9152\uff0c\u800c\u4e14\u6bd4\u6b63\u5e38\u5c0f\u9f20\u9009\u62e9\u559d\u66f4\u591a\u7684\u9152\u3002\u4e00\u9879\u6839\u636e10\u4e07\u591a\u6b27\u6d32\u4eba\u540e\u88d4\u7684\u7814\u7a76\u53d1\u73b0\uff0c\u4ed6\u4eec\u53d1\u73b0\u6709\u4e00\u4e2abeta-Klotho\u57fa\u56e0\u4e9a\u578b\uff0c\u540c\u65f6\u996e\u9152\u91cf\u5e73\u5747\u8f83\u5c11\u3002UTSW\u56e2\u961f\u4e0e\u7f8e\u56fd\uff0c\u6b27\u6d32\u548c\u4e2d\u56fd\u7684\u5176\u4ed6\u7814\u7a76\u56e2\u961f\u5408\u4f5c\uff0c\u901a\u8fc7\u5168\u57fa\u56e0\u7ec4\u5173\u8054\u7814\u7a76\uff0c\u53d1\u73b0beta-Klotho\u8fd9\u79cd\u5173\u8054\u3002 \u5b83\u4e0eFGF21\u548cFGF19\u57fa\u56e0\u534f\u540c\u5de5\u4f5c\u3002 \u8fd9\u4e24\u4e2a\u57fa\u56e0\u63a7\u5236\u4e0e\u9152\u7cbe\u504f\u597d\u76f8\u5173\u7684\u76f8\u540c\u540d\u79f0\u7684\u6fc0\u7d20\uff0c\u4ee5\u53ca\u6e34\u671b\u751c\u7684\u98df\u7269\u3002<\/div>\n
\u53c2\u8003\uff1ahttp:\/\/www.nbcnews.com\/health\/health-news\/gene-might-affect-how-much-you-drink-n689156<\/div>\n
\u00a0<\/div>\n
\u8840\u6db2\u6837\u672c\u4e2d\u7684DNA\u7a81\u53d8\u53ef\u80fd\u4e3a\u68c0\u6d4b\u8bca\u65ad\u80a0\u9053\u708e\u75c7\uff08IBD\uff09\u63d0\u4f9b\u7ebf\u7d22<\/div>\n
\u80a0\u9053\u708e\u75c7<\/div>\n
\u7531\u7231\u4e01\u5821\u5927\u5b66\u534f\u8c03\u7684\u56fd\u9645\u56e2\u961f\u5206\u6790\u4e86\u6765\u81ea240\u4f4d\u65b0\u8bca\u65ad\u4e3aIBD\u7684\u4eba\u7684DNA\u6837\u672c\u3002 \u4ed6\u4eec\u53d1\u73b0\uff0c\u60a3\u8005DNA\u4e2d\u7684\u5316\u5b66\u7279\u5f81\uff08\u79f0\u4e3a\u8868\u89c2\u9057\u4f20\u53d8\u5316\uff09\u4e0e\u5065\u5eb7\u4eba\u7684\u7279\u5f81\u4e0d\u540c\u3002<\/div>\n
\u53c2\u8003\uff1ahttp:\/\/www.news-medical.net\/news\/20161128\/DNA-changes-in-blood-samples-could-pave-way-for-simple-tests-to-diagnose-IBD.aspx<\/div>\n
\u00a0<\/div>\n
\u4ea7\u4e1a\u65b0\u95fb<\/div>\n\n<\/div>\n
<\/div>\n
\u751f\u7269\u5236\u836f\u516c\u53f8Celgene\u878d\u8d44$10M\u540e\u7b2c\u4e8c\u6b21\u6295\u5165\u8d2d\u4e70GNS Healthcare\u7684\u673a\u5668\u5b66\u4e60\u8f6f\u4ef6<\/div>\n
Celgene\u6295\u8d44\u673a\u5668\u5b66\u4e60\u8f6f\u4ef6<\/div>\n
\u6839\u636e\u661f\u671f\u4e8c\u516c\u5e03\u7684\u534f\u8bae\uff0cCelgene\uff08\u7eb3\u65af\u8fbe\u514b\u80a1\u7968\u4ee3\u7801\uff1aCELG\uff09\u5df2\u6388\u6743\u4f7f\u7528GNS Healthcare\u7684\u201c\u9006\u5411\u5de5\u7a0b\u548c\u524d\u5411\u6a21\u62df\u201d\u8f6f\u4ef6\u3002 \u8be5\u6280\u672f\u5305\u62ec\u7535\u5b50\u5065\u5eb7\u8bb0\u5f55\uff0c\u836f\u5b66\u548c\u533b\u7597\u7d22\u8d54\uff0c\u57fa\u56e0\u7ec4\u6d4b\u5e8f\u7b49\u66f4\u591a\u7684\u5065\u5eb7\u6570\u636e – \u5e76\u5e94\u7528\u673a\u5668\u5b66\u4e60\u6280\u672f\u6765\u5c1d\u8bd5\u548c\u56de\u7b54\u533b\u7597\u4fdd\u5065\u4e2d\u7684\u590d\u6742\u95ee\u9898\uff0c\u4f8b\u5982\u9884\u6d4b\u54ea\u4e9b\u6cbb\u7597\u65b9\u6cd5\u6700\u9002\u5408\u4e2a\u522b\u60a3\u8005\u3002<\/div>\n
\u53c2\u8003\uff1ahttp:\/\/www.xconomy.com\/boston\/2016\/11\/29\/celgene-invests-more-in-gns-healthcare-licenses-analytics-software\/#<\/div>\n
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\u4e0a\u5468GenomeWeb\u6587\u7ae0\u7cbe\u9009<\/div>\n
GenomeWeb<\/div>\n
1\uff09CMS 2017\u5e74\u5b9a\u4ef7\u7ed9\u51e0\u4e2a\u5206\u5b50\u8bca\u65ad\u516c\u53f8\u5e26\u6765\u597d\u6d88\u606f2\uff09FDA\u63a8\u8fdf\u5b8c\u6210\u5b9e\u9a8c\u5ba4\u5f00\u53d1\u6d4b\u8bd5\u76d1\u7ba1\u6307\u53573\uff09\u5728\u5927\u578b\u7cbe\u795e\u5b66\u57fa\u56e0\u7814\u7a76\u8054\u76df\uff08 Large Psychiatric Genomics Consortium Study\uff09\u53d1\u73b0\u65b0\u7684\u7cbe\u795e\u5206\u88c2\u75c7\u76f8\u5173\u62f7\u8d1d\u6570\u53d8\u5f024\uff09\u6851\u683c\u7814\u7a76\u6240\uff0cWellcome\u57fa\u56e0\u5927\u5b66\u5f00\u653e\u65b0\u7684\u6d4b\u5e8f\u4e0e\u751f\u7269\u6570\u636e\u4e2d\u5fc35\uff09Genalyte\u83b7\u5f973600\u4e07\u7f8e\u5143\u7684\u8d44\u91d1 \u53c2\u8003\uff1ahttps:\/\/www.genomeweb.com\/top-five-articles-genomeweb-last-week-cms-pricing-lab-tests-ldt-guidance-put-and-more<\/div>\n
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\u80bf\u7624\u548c\u8868\u89c2\u9057\u4f20\u5b66<\/div>\n
\u8fbe\u7279\u9ed8\u65afGeisel \u533b\u5b66\u5b66\u9662\u7684\u7814\u7a76\u4eba\u5458\u53d1\u73b0\u4e00\u4e2a\u4f4e\u6c34\u5e73\u7684\u7279\u5b9a\u8868\u89c2\u9057\u4f20\u6807\u8bb0\u4e0e\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\u60a3\u8005\u7684\u8f83\u5dee\u9884\u540e\u76f8\u5173\u3002\u7814\u7a76\u4eba\u5458\u4ee55-\u7532\u57fa\u80de\u5627\u5576\uff085mC\uff09\u548c5-\u7f9f\u7532\u57fa\u80de\u5627\u5576\uff085hmC\uff09\u4e3aDNA\u4fee\u9970\u7279\u5f81\u7814\u7a76\u4e8630\u4e2a\u80f6\u8d28\u6bcd\u7ec6\u80de\u7624\uff08GBM\uff09\u6837\u672c\u3002<\/div>\n
\u53c2\u8003\uff1ahttps:\/\/www.genomeweb.com\/cancer\/epigenetic-markers-glioblastoma-linked-poor-prognosis<\/div>\n
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\u8de8\u754c\u94fe\u63a5<\/div>\n
\n\n<\/div>\n
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\u6700\u5927\u7684\u4eba\u7c7b\u201c\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u6570\u636e\u201d\u53ef\u4ee5\u5e2e\u52a9\u89e3\u91ca\u57fa\u56e0\u6570\u636e<\/div>\n
\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u6570\u636e\u5e93<\/div>\n
\u4e00\u4e2a\u56fd\u9645\u7814\u7a76\u5c0f\u7ec4\u5f00\u53d1\u4e86\u6700\u5927\u7684\u86cb\u767d\u8d28\u76f8\u4e92\u4f5c\u7528\u7f51\u7edc\u6570\u636e\u5e93\uff0c\u8fd9\u4e00\u8d44\u6e90\u53ef\u4ee5\u7167\u4eae\u8bb8\u591a\u75be\u75c5\u76f8\u5173\u7684\u57fa\u56e0\u5e76\u6709\u52a9\u4e8e\u7814\u7a76\u75be\u75c5\u3002\u7531\u9a6c\u8428\u8bf8\u585e\u5dde\u603b\u533b\u9662\uff08MGH\uff09\u3001\u54c8\u4f5b\u548c\u9ebb\u7701\u7406\u5de5Broad\u7814\u7a76\u6240\u5e26\u9886\u7684\u7f51\u7edc\u5f00\u53d1\u56e2\u961f\u62a5\u544a\uff0cNature Methods\u5c06\u63a5\u53d7\u8fd9\u4e2a\u79f0\u4e3aInWeb_InBioMap (InWeb_IM) \u7684\u7f51\u7edc\u63d0\u524d\u5728\u7ebf\u53d1\u884c\u3002<\/div>\n
\u53c2\u8003\uff1ahttp:\/\/medicalxpress.com\/news\/2016-11-largest-resource-human-protein-protein-interactions.html<\/div>\n
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\u52a0\u70b9\u5c0f\u83dc<\/p>\n
\u5206\u4eab\u7ed9\u60a8\uff0c\u90e8\u5206\u53c2\u8003\u7f51\u7ad9<\/div>\n
Naturewww.nature.com<\/a><\/div>\n
Cell www.cell.com<\/div>\n
Scienceewww.sciencemag.org<\/div>\n
The Lancetwww.thelancet.com<\/div>\n
nejmwww.nejm.org<\/a><\/div>\n
genomeweb www.genomeweb.com<\/div>\n
GENwww.genengnews.com<\/a><\/div>\n
Medical Xpressmedicalxpress.com<\/a><\/div>\n
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\u5982\u9700\u6bcf\u5929\u81ea\u52a8\u6536\u5230\u77e5\u8bc6\u52a9\u7406\u201cGeneMail\u201d\u9ad8\u6e05\u6587\u4ef6<\/div>\n
\u6b22\u8fce\u8ba2\u9605 \u261f<\/div>\n
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\"eicZhoGYCfyboyIeahsibN0sa4cH3y0LuqqKUEIOHNJHZBpE7d8WJgpXW0UkqOG5lK8Axm7TmOBb11GRtOBDwYlw\"\/<\/figure><\/div>\n\n<\/div>\n
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\u9ed1\u91d1\u5361\u4f1a\u5458\u4e13\u4eab<\/div>\n
\u3010\u57fa\u56e0\u6167\u9ed1\u91d1\u5361\u4f1a\u5458\u3011\u6fc0\u6d3b\u540e \uff08\u89c1\u5361\u80cc\u9762\uff09\uff0c\u6bcf\u65e5\u53ef\u81ea\u52a8\u6536\u5230\u201c\u77e5\u8bc6\u52a9\u7406\u201dGeneMail\u9ad8\u6e05PDF\u6587\u4ef6\uff08\u542b\u8d44\u8baf\u8d85\u94fe\u63a5\uff09<\/div>\n
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\u7cbe\u534e\u6587\u7ae0<\/p>\n
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59 \u3010ACMG\u3011ACMG \u66f4\u65b0\u89e3\u8bfb\uff0835\u9875PPT)<\/a><\/div>\n
57 \u3010\u8f85\u52a9\u8bca\u65ad\u3011\u4e34\u5e8a\u57fa\u56e0\u68c0\u6d4b\u7684\u75db\u70b9\u548c\u65b9\u6848<\/a><\/div>\n
56 \u3010GeneMail\u3011\u7cbe\u51c6\u533b\u7597\u6bcf\u65e5\u8d44\u8baf<\/a><\/div>\n
54 \u3010\u5341\u5e74\u3011\u5168\u56fd500\u4f59\u5bb6\u80bf\u7624\u7cbe\u51c6\u533b\u7597\u4f01\u4e1a<\/a><\/div>\n
52 \u3010NGS\u5e94\u7528\u3011NGS\u5728\u9057\u4f20\u75c5\u8bca\u65ad\u4e2d\u7684\u5e94\u7528<\/a><\/div>\n
51 \u3010\u9057\u4f20\u5927\u4f1a\u3011\u7b2c\u5341\u5c4a\u5168\u56fd\u9057\u4f20\u75c5\u8bca\u65ad\u548c\u4ea7\u524d\u8bca\u65ad\u5b66\u672f\u4ea4\u6d41\u4f1a\u4f1a\u8bae\u7b14\u8bb0<\/a><\/div>\n
50 \u3010\u80bf\u7624\u62a5\u544a\u3011\u80bf\u7624\u7cbe\u51c6\u533b\u7597\u8c03\u7814\u62a5\u544a\uff08130\u9875\uff09<\/a><\/div>\n
49 \u3010\u6db2\u4f53\u6d3b\u68c0\u301115\u5bb6\u80bf\u7624\u4f01\u4e1a\u5927\u5496\u89e3\u8bfb\u5171\u8bc6<\/a><\/div>\n
46 \u3010\u7f55\u89c1\u75c5\u3011\u79d1\u5b66\u8ba4\u8bc6\u7f55\u89c1\u75c5\uff0870\u9875PPT)<\/a><\/div>\n
45 \u3010\u5fae\u751f\u7269\u3011\u80a0\u9053\u5fae\u751f\u7269\u7ec4<\/a><\/div>\n
43 \u3010\u961f\u5217\u3011\u56fd\u5185\u591650\u4f59\u4e2a\u7cbe\u51c6\u533b\u5b66\u961f\u5217\u9879\u76ee<\/a><\/div>\n
40 \u3010Panel\u3011Cancer Panel\u6807\u51c6\u5316\u7814\u8ba8\u4f1aPPT\u7cbe\u534e<\/a><\/div>\n
39 \u3010\u9776\u5411\u836f\u3011\u80bf\u7624\u9776\u5411\u6cbb\u7597\u548c\u9776\u5411\u836f<\/a><\/div>\n
28\u3010\u57fa\u56e0\u8bca\u65ad\u3011\u54c8\u4f5b\u6c88\u4ea6\u5e73\u8c08\u57fa\u56e0\u8bca\u65ad<\/a><\/div>\n
20\u3010\u751f\u7269\u4fe1\u606f\u3011\u751f\u7269\u4fe1\u606f\u57f9\u8bad\u8d44\u6599\u63a8\u8350 <\/a><\/div>\n
19 \u3010\u4e91\u5e73\u53f0\u3011\u9996\u5c4a\u57fa\u56e0\u7ec4\u4e91\u5927\u4f1aPPT\u7cbe\u534e<\/a><\/div>\n
17 \u3010\u6db2\u4f53\u6d3b\u68c0\u3011\u4e00\u5957PPT\u8bfb\u61c2\u6db2\u4f53\u6d3b\u68c0<\/a><\/div>\n
15\u3010\u57fa\u56e0\u7f16\u8f91\u3011 \u57fa\u56e0\u7f16\u8f91\u7684\u6280\u672f\u548c\u539f\u7406<\/a><\/div>\n
8 \u3010\u4eba\u5de5\u667a\u80fd\u3011 \u4eba\u5de5\u667a\u80fd+\u57fa\u56e0\u5065\u5eb7<\/a><\/div>\n
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\u7535\u8bdd\uff1a010-56527551 \/ 400-088-7466<\/div>\n
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\u5b98\u7f51\uff1awww.geneclub.net.cn<\/div>\n
\u90ae\u7bb1\uff1ainfo@genonet.cn<\/div>\n
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