{"id":11620,"date":"2017-03-23T11:10:14","date_gmt":"2017-03-23T03:10:14","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMzE4MzU3NA==&mid=504149352&idx=1&sn=36e43a2a0f91b8b6e90342d3cbd1bf90&chksm=7371955144061c4744d8a3c239408db6fce614dc808bf31cf83dac1655b41cbd29a607914530#rd"},"modified":"2026-04-09T10:47:20","modified_gmt":"2026-04-09T02:47:20","slug":"4997102","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2017\/03\/23\/4997102\/","title":{"rendered":"\u4e0a\u6d77\u4ea4\u5927\u65bd\u5947\u60e0\u6559\u6388\uff1a\u7a00\u6709\u80bf\u7624\u7ec6\u80de\u9274\u5b9a\u548c\u5355\u7ec6\u80de\u6d4b\u5e8f |\u300a\u5927\u5496\u8bba\u5065\u300b\u7b2c24\u671f"},"content":{"rendered":"

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\u300a\u5927\u5496\u8bba\u5065\u300b\u603b\u7b2c25\u671f<\/div>\n
\u65bd\u5947\u60e0 \u6559\u6388<\/div>\n
\u5173\u952e\u8bcd\uff1a\u7a00\u6709\u80bf\u7624\u7ec6\u80de\u9274\u5b9a CTC<\/div>\n
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\"eicZhoGYCfyaict3PdnQoksESCUl9yvAGYYFleP2ibCa69h1Xe2HExZkdDHUJRkLdIjP5zKIvPNC9cn0Hne9xrFcA\"\/<\/figure><\/div>\n\n
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\u00a0<\/div>\n
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\u7ea2\u6749\u4e2d\u56fd-\u6768\u4e91\u971e<\/a> |WeGene-\u9648\u94a2<\/a> | \u7cbe\u51c6\u57fa\u56e0-\u5f20\u6d69<\/a>| \u57fa\u4e91\u60e0\u5eb7-\u90dd\u5411\u7a33<\/a>|\u9510\u7fcc\u751f\u7269-\u79e6\u6960<\/a>| \u6cdb\u751f\u5b50-\u960e\u6d77<\/a>| \u6d77\u666e\u6d1b\u65af-\u8bb8\u660e\u708e<\/a> | \u67f4\u6620\u723d<\/a> | \u601d\u8def\u8fea-\u718a\u78ca<\/a> | \u836f\u660e\u5eb7\u5fb7\u660e\u7801\u751f\u7269-\u5b59\u6d2a\u4e1a<\/a> | \u534e\u5927\u57fa\u56e0-\u5c39\u70e8<\/a>| \u9ec4\u5c1a\u5fd7<\/a> | \u4e2d\u65e5\u533b\u9662-\u987e\u536b\u7ea2<\/a> | \u897f\u5357\u533b\u9662-\u59da\u5b8f<\/a> | \u534f\u548c\u533b\u9662-\u8d75\u6d77\u6d9b<\/a> |\u590d\u65e6\u9644\u5c5e\u513f\u79d1\u533b\u9662-\u738b\u827a<\/a> |\u5317\u5927\u4e00\u9662-\u4e01\u6d01<\/a>|\u6d59\u6c5f\u5927\u5b66-\u7941\u9e23<\/a> |\u4e0a\u6d77\u513f\u7ae5\u533b\u9662-\u738b\u4f1f<\/a> |\u6e05\u534e\u5927\u5b66-\u6234\u4fca\u5f6a<\/a>|\u534e\u5927\u57fa\u56e0-\u6c88\u73a5<\/a> |\u8f9b\u8f9b\u90a3\u63d0\u513f\u7ae5\u533b\u9662-\u9ec4\u6d9b\u751f<\/a>|Sidney Kimmel\u764c\u75c7\u4e2d\u5fc3-\u6768\u864e\u5c71<\/a><\/div>\n
\u00a0<\/div>\n
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cfDNA\u5927\u6570\u636e\u548c\u764c\u75c7\u65e9\u7b5b<\/div>\n
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\"eicZhoGYCfyaict3PdnQoksESCUl9yvAGYtRMDLse5nyuVbbTGRvZRB6t2rYteAYuNp354KzBPDe6ibucy2NMKTrw\"\/<\/figure><\/div>\n\n
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\u65bd\u6559\u6388\uff1a\u6211\u9996\u5148\u7b80\u5355\u4ecb\u7ecd\u4e0b\u6211\u7684\u6c42\u5b66\u4e0e\u5de5\u4f5c\u7ecf\u5386\u3002\u62112003\u5e74\u6bd5\u4e1a\u4e8e\u590d\u65e6\u5927\u5b66\u5316\u5b66\u7cfb\uff0c2003\u81f32008\u5e74\u5728\u52a0\u5dde\u5927\u5b66\u5723\u82ad\u82ad\u62c9\u5206\u6821\uff08UCSB\uff09\u5316\u5b66\u7cfb\u653b\u8bfb\u535a\u58eb\u5b66\u4f4d\uff0c\u5e08\u4eceGalen Stucky\u6559\u6388\u3002Stucky\u6559\u6388\u662f\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u58eb\uff0c\u662f\u5316\u5b66\u548c\u6750\u6599\u9886\u57df\u53d1\u8868\u8bba\u6587\u5f15\u7528\u7387\u6700\u9ad8\u7684\u79d1\u5b66\u5bb6\u4e4b\u4e00\u3002<\/div>\n
\u00a0<\/div>\n
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\u00a0<\/div>\n
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Heath\u6559\u6388\u662f\u7eb3\u7c73\u7535\u5b50\u5b66\u9886\u57df\u7684\u6743\u5a01\uff0c\u83b7\u5f97\u8fc7\u8d39\u66fc\u5956\uff082000\u5e74\uff09\uff0c\u66fe\u521b\u529eCalifornia NanoSystem Institute\uff08\u52a0\u5dde\u7eb3\u7c73\u7cfb\u7edf\u7814\u7a76\u9662\uff0cCNSI\uff09\u3002\u4ed6\u6700\u521d\u7684\u6210\u5c31\u6765\u81ea\u4e8e\u7814\u7a76\u751f\u65f6\u4ee3\u4e0eSean O’Brien\u3001Richard Smalley\uff08Heath\u7684\u5bfc\u5e08\uff09\u3001Harold Kroto\u3001Robert Curl\u5171\u540c\u53d1\u73b0\u4e86C60\u3002C60\u7684\u53d1\u73b0\u53ef\u4ee5\u8bf4\u662f\u6574\u4e2a\u7eb3\u7c73\u79d1\u5b66\u7684\u5f00\u7aef\uff0c\u800cRichard Smalley\u3001Harold Kroto\u548cRobert Curl\u4e5f\u88ab\u5171\u540c\u6388\u4e88\u4e861996\u5e74\u7684\u8bfa\u8d1d\u5c14\u5316\u5b66\u5956\u3002Heath\u6559\u6388\u7684\u7814\u7a76\u5174\u8da3\u4e0e\u91cd\u5fc3\u57282005\u5e74\u540e\u4ece\u7eb3\u7c73\u7535\u5b50\u5b66\u3001\u5206\u5b50\u7535\u5b50\u5b66\u9010\u6e10\u8f6c\u79fb\u5230\u4e86\u764c\u75c7\u7814\u7a76\u3002\u5728NIH\u7684\u8d44\u52a9\u4e0b\uff0c\u4ed6\u5efa\u7acb\u4e86NanoSystems Biology CancerCenter\uff08\u7eb3\u7c73\u7cfb\u7edf\u751f\u7269\u5b66\u764c\u75c7\u4e2d\u5fc3\uff0cNSBCC\uff09\u3002\u8fd9\u5bf9\u6211\u6765\u8bf4\u662f\u4e00\u4e2a\u975e\u5e38\u597d\u7684\u673a\u4f1a\uff0c\u56e0\u4e3a\u5728NSBCC\u6211\u4e00\u65b9\u9762\u6211\u53ef\u4ee5\u6709\u65f6\u95f4\u91cd\u65b0\u5b66\u4e60\uff0c\u53e6\u4e00\u65b9\u9762\u4e5f\u53ef\u4ee5\u901a\u8fc7NSBCC\u7684\u5408\u4f5c\u673a\u5236\u5411\u751f\u7269\u533b\u5b66\u65b9\u9762\u7684\u5b66\u8005\u4ee5\u53ca\u4e34\u5e8a\u533b\u751f\u5b66\u4e60\u3002<\/div>\n
\u6211\u5728\u52a0\u5dde\u7406\u5de5\u5b66\u9662\u4e3b\u8981\u4ece\u4e8b\u5355\u7ec6\u80de\u86cb\u767d\u7ec4\u68c0\u6d4b\u65b9\u9762\u7684\u7814\u7a76\uff0c\u5e76\u4e0e\u540c\u4e8b\u5408\u4f5c\u8fdb\u884c\u4e86\u4e00\u4e9b\u4e34\u5e8a\u6837\u672c\u7684\u68c0\u6d4b\uff0c\u5728PNAS\uff08\u7b2c\u4e00\u4f5c\u8005\uff09[1,2]\u3001Nature Medicine\uff08\u5171\u540c\u4f5c\u8005\uff09[3]\u7b49\u6742\u5fd7\u4e0a\u53d1\u8868\u4e86\u8bba\u6587\u3002\u56de\u56fd\u540e\u6211\u52a0\u5165\u4e86\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u7cfb\u7edf\u751f\u7269\u533b\u5b66\u7814\u7a76\u9662\uff0c\u5c06\u7814\u7a76\u65b9\u5411\u4e0e\u4e34\u5e8a\u8d34\u5408\u5f97\u66f4\u52a0\u7d27\u5bc6\u3002<\/div>\n\n
\n
\"eicZhoGYCfyaict3PdnQoksESCUl9yvAGYAQUFhW244zfayoRCb08W5l0dkUxCibCtarMpgOfGOgBKjgicEw5XXmKA\"\/<\/figure><\/div>\n\n
\u56fe\uff1aThe single-cell barcode chip\uff0c\u6765\u81ea\u53c2\u8003\u6587\u732e[2]<\/div>\n
\u4e8c\u3001\u4ece\u52a0\u5dde\u7406\u5de5\u5b66\u9662\u5230\u4e0a\u6d77\u4ea4\u5927<\/div>\n
\u57fa\u56e0\u6167\uff1a\u60a82011\u5e74\u5728\u52a0\u5dde\u7406\u5de5\u5b66\u9662\u5b8c\u6210\u535a\u58eb\u540e\u7814\u7a76\u540e\uff0c\u5a49\u62d2\u4e86\u7f8e\u56fd\u7684tenure-track\u7684\u52a9\u7406\u6559\u6388\u804c\u4f4d\uff0c\u56de\u56fd\u52a0\u5165\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u7cfb\u7edf\u751f\u7269\u533b\u5b66\u7814\u7a76\u9662\uff0c\u7b2c\u4e8c\u5e74\u5165\u9009\u4e86\u7b2c\u4e8c\u6279\u56fd\u5bb6\u9752\u5e74\u5343\u4eba\u8ba1\u5212\u3002\u60a8\u80fd\u548c\u57fa\u56e0\u6167\u7684\u8bfb\u8005\uff0c\u7279\u522b\u662f\u7559\u5b66\u5f52\u6765\u7684\u79d1\u7814\u5b66\u8005\uff0c\u5728\u4e0d\u540c\u79d1\u7814\u548c\u5de5\u4f5c\u73af\u5883\u4e2d\u9002\u5e94\u7684\u7ecf\u9a8c\u5417\uff1f<\/div>\n
\u65bd\u6559\u6388\uff1a\u6211\u56de\u56fd\u53d1\u5c55\u7684\u4e3b\u8981\u539f\u56e0\u662f\u5bb6\u5ead\u56e0\u7d20\uff0c\u5f53\u71362010\u5e74\u7f8e\u56fd\u6b63\u5904\u4e8e\u7ecf\u6d4e\u5371\u673a\u4e2d\uff0c\u5f88\u591a\u5b66\u6821\u90fd\u51cf\u5c11\u751a\u81f3\u53d6\u6d88\u4e86\u62db\u8058\u8ba1\u5212\uff0c\u804c\u4f4d\u6bd4\u8f83\u7a00\u5c11\uff0c\u62ff\u5230tenure-track\u7684\u52a9\u7406\u6559\u6388\u804c\u4f4d\u5e76\u4e0d\u5bb9\u6613\u3002\u5bf9\u4e8e\u56de\u56fd\u53d1\u5c55\u800c\u8a00\uff0c\u6211\u89c9\u5f97\u6bd4\u8f83\u6709\u5229\u7684\u4e00\u70b9\u662f\u4e00\u76f4\u4ee5\u6765\u6211\u90fd\u4e0e\u56fd\u5185\u5b66\u672f\u754c\u4fdd\u6301\u4e86\u6bd4\u8f83\u5bc6\u5207\u7684\u8054\u7cfb\uff0c\u5bf9\u56fd\u5185\u7684\u60c5\u51b5\u4e5f\u6bd4\u8f83\u719f\u6089\uff0c\u6240\u4ee5\u4e0d\u5b58\u5728\u90a3\u79cd\u51fa\u56fd\u592a\u4e45\uff0c\u4e00\u671d\u56de\u56fd\u6c34\u571f\u4e0d\u670d\u7684\u60c5\u51b5\u3002<\/div>\n
\u4f46\u5373\u4f7f\u5982\u6b64\uff0c\u56de\u56fd\u81ea\u5df1\u5efa\u7acb\u8bfe\u9898\u7ec4\u4ecd\u6709\u5f88\u591a\u6311\u6218\uff0c\u6211\u8ba4\u4e3a\u8fd9\u4e9b\u6311\u6218\u6216\u8005\u8bf4\u4e0d\u9002\u5e94\u4e3b\u8981\u662f\u7531\u4e8e\u8eab\u4efd\u6539\u53d8\u9020\u6210\u7684\uff0c\u5c31\u662f\u4ece\u8bfe\u9898\u7ec4\u6210\u5458\u53d8\u6210\u4e86\u8bfe\u9898\u7ec4\u7ec4\u957f\uff08PI\uff09\u540e\uff0c\u5f88\u591a\u539f\u5148\u4e0d\u9700\u8981\u64cd\u5fc3\u6216\u8005\u6839\u672c\u6ca1\u6709\u63a5\u89e6\u8fc7\u7684\u4e8b\u60c5\u90fd\u9700\u8981\u53bb\u505a\u3002PI\u7684\u8eab\u4efd\u5bf9\u4e00\u4e2a\u79d1\u5b66\u5bb6\u7684\u8981\u6c42\u662f\u5168\u9762\u7684\uff0c\u4ed6\u4e0d\u4ec5\u8981\u5173\u6ce8\u5b66\u672f\u65b9\u9762\uff0c\u5199\u8bba\u6587\u7533\u8bf7\u9879\u76ee\uff0c\u8fd8\u8981\u62db\u5b66\u751f\u6307\u5bfc\u5b66\u751f\u5e76\u627f\u62c5\u6559\u5b66\u4efb\u52a1\uff0c\u540c\u65f6\u9700\u8981\u4e86\u89e3\u8d22\u52a1\u3001\u91c7\u8d2d\u62db\u6807\u7b49\u6d41\u7a0b\uff0c\u53c2\u4e0e\u5404\u79cd\u9662\u5185\u4e8b\u52a1\u4ee5\u53ca\u5404\u79cd\u9879\u76ee\u8bc4\u5ba1\u3001\u8bba\u6587\u8bc4\u8bae\u7b49\u7b49\u3002\u5c24\u5176\u662f\u6211\u5e0c\u671b\u81ea\u5df1\u6709\u4e00\u4e2a\u4e0d\u540c\u4e8e\u4ee5\u524d\u7684\u7814\u7a76\u65b9\u5411\uff0c\u5efa\u7acb\u81ea\u5df1\u7684\u5b66\u672f\u58f0\u8a89\uff0c\u8fd9\u5c31\u9700\u8981\u5728\u5b66\u672f\u4e0a\u4ed8\u51fa\u66f4\u591a\u7684\u52aa\u529b\u3002<\/div>\n
\u00a0<\/div>\n
\u4e09\u3001\u8bca\u65ad\u4eea\u5668\u91cd\u5728\u65b9\u6cd5\u5b66\u521b\u65b0\u548c\u673a\u5236\u4fdd\u8bc1<\/div>\n
\u57fa\u56e0\u6167\uff1a\u76ee\u524d\u5c31\u4e34\u5e8a\u8bca\u65ad\u4eea\u5668\u9886\u57df\u800c\u8a00\uff0c\u56fd\u5916\u4f9d\u7136\u9886\u5148\u4e00\u6bb5\u8ddd\u79bb\uff0c\u60a8\u8ba4\u4e3a\u5176\u4e2d\u7684\u5173\u952e\u56e0\u7d20\u662f\u4ec0\u4e48\u5462\uff0c\u5728\u9ad8\u7cbe\u5bc6\u4eea\u5668\u7279\u522b\u662f\u4e34\u5e8a\u8bca\u65ad\u4eea\u5668\u7814\u53d1\uff0c\u6211\u4eec\u9700\u8981\u6539\u5584\u6216\u8005\u5b66\u4e60\u7684\u65b9\u9762\u6709\u54ea\u4e9b\u5462\uff1f<\/div>\n
\u65bd\u6559\u6388\uff1a\u8fd9\u4e2a\u9898\u76ee\u6bd4\u8f83\u5927\uff0c\u6211\u53ea\u80fd\u4ece\u81ea\u5df1\u7684\u89d2\u5ea6\u7ed9\u4e88\u4e00\u4e9b\u770b\u6cd5\u3002\u6b27\u7f8e\u5728\u4e34\u5e8a\u8bca\u65ad\u4eea\u5668\u548c\u9ad8\u7cbe\u5bc6\u4eea\u5668\u65b9\u9762\u7684\u9886\u5148\u9996\u5148\u5f53\u7136\u662f\u56e0\u4e3a\u957f\u671f\u3001\u6301\u7eed\u6027\u7684\u7814\u53d1\u6295\u5165\uff0c\u76f8\u6bd4\u4e4b\u4e0b\u56fd\u5185\u7684\u79ef\u7d2f\u5c31\u663e\u5f97\u8fdc\u8fdc\u4e0d\u591f\uff0c\u65e0\u8bba\u5728\u6280\u672f\u65b9\u9762\u8fd8\u662f\u4eba\u624d\u65b9\u9762\uff0c\u4ea6\u6216\u662f\u914d\u5957\u4ea7\u4e1a\u65b9\u9762\u90fd\u663e\u4e0d\u8db3\u3002\u53ef\u559c\u7684\u662f\u76ee\u524d\u56fd\u5185\u5df2\u7ecf\u6709\u4e86\u4e00\u4e9b\u6bd4\u8f83\u6709\u5b9e\u529b\u7684\u516c\u53f8\u80fd\u591f\u4ece\u4e8b\u8f83\u597d\u7684\u4ea7\u54c1\u5f00\u53d1\u4e0e\u4f18\u5316\u3002\u76f8\u6bd4\u4e8e\u5927\u516c\u53f8\u5de8\u989d\u7684\u7814\u53d1\u6295\u5165\u3001\u4e30\u5bcc\u7684\u4eba\u529b\u8d44\u6e90\u4ee5\u53ca\u957f\u671f\u79ef\u7d2f\uff0c\u5b66\u672f\u754c\u5728\u5f88\u591a\u9886\u57df\u7279\u522b\u662f\u7cbe\u5bc6\u4eea\u5668\u7684\u7814\u53d1\u4e0a\u5e76\u6ca1\u6709\u90a3\u4e48\u4e30\u5bcc\u7684\u8d44\u6e90\u3002<\/div>\n
\u00a0<\/div>\n
\u6240\u4ee5\u6211\u8ba4\u4e3a\u6700\u597d\u80fd\u591f\u805a\u7126\u4e8e\u4e0a\u6e38\u65b9\u6cd5\u5b66\u7684\u521b\u65b0\uff0c\u4e5f\u5c31\u662f\u53d1\u5c55\u98a0\u8986\u6027\u7684\u65b0\u6280\u672f\u6765\u5b9e\u73b0\u5728\u8fd9\u4e2a\u9886\u57df\u7684\u5f2f\u9053\u8d85\u8f66\uff0c\u540c\u65f6\u4e5f\u9700\u8981\u4e00\u4e9b\u673a\u5236\u7684\u4fdd\u8bc1\u6765\u4fc3\u8fdb\u79d1\u7814\u6210\u679c\u7684\u4ea7\u4e1a\u5316\u3002\u6211\u4eec\u7ecf\u5e38\u53ef\u4ee5\u770b\u5230\u56fd\u5916\u4e00\u7bc7\u65b9\u6cd5\u5b66\u7684\u6587\u7ae0\u5728\u9876\u5c16\u671f\u520a\u4e0a\u53d1\u8868\uff0c\u6ca1\u8fc7\u591a\u4e45\u5c31\u6709\u4e00\u4e2a\u516c\u53f8\u5c06\u5176\u4ea7\u54c1\u5316\u5e76\u4e0a\u5e02\u9500\u552e\uff0c\u79d1\u7814\u6210\u679c\u8f6c\u5316\u7684\u6548\u7387\u975e\u5e38\u9ad8\u3002<\/div>\n
\u79d1\u7814\u6210\u679c\u8f6c\u5316\u7684\u4e00\u79cd\u65b9\u5f0f\u662f\u5c06\u6280\u672f\u8f6c\u8ba9\u7ed9\u6709\u5b9e\u529b\u7684\u516c\u53f8\u8fdb\u884c\u4ea7\u54c1\u5f00\u53d1\uff0c\u53e6\u4e00\u79cd\u5219\u662f\u79d1\u5b66\u5bb6\u81ea\u5df1\u521b\u529e\u4f01\u4e1a\u8fdb\u884c\u6280\u672f\u7684\u4ea7\u4e1a\u5316\u3002\u7531\u4e8e\u5b9e\u9a8c\u5ba4\u7814\u53d1\u7684\u6280\u672f\u5f80\u5f80\u4e0e\u6700\u7ec8\u7684\u4ea7\u54c1\u4ecd\u6709\u8f83\u5927\u7684\u8ddd\u79bb\uff0c\u8fd8\u9700\u8981\u6295\u5165\u5f88\u591a\u7684\u8d44\u6e90\u8fdb\u884c\u4ea7\u54c1\u5f00\u53d1\uff0c\u751a\u81f3\u5728\u4ea7\u54c1\u5f00\u53d1\u8fc7\u7a0b\u4e2d\u7531\u4e8e\u5e02\u573a\u5b9a\u4f4d\u7684\u95ee\u9898\u8fd8\u9700\u8981\u505a\u8c03\u6574\uff0c\u8fdb\u884c\u4e8c\u6b21\u7814\u53d1\uff0c\u56e0\u6b64\u6574\u4e2a\u4ea7\u4e1a\u5316\u7684\u8fc7\u7a0b\u5f80\u5f80\u662f\u6bd4\u8f83\u6f2b\u957f\u800c\u4e0d\u786e\u5b9a\u7684\uff0c\u5c24\u5176\u5bf9\u4e8e\u521b\u65b0\u533b\u7597\u5668\u68b0\u8fd8\u6d89\u53ca\u4e34\u5e8a\u533b\u751f\u7684\u63a5\u53d7\u4ee5\u53ca\u5408\u89c4\u95ee\u9898\u3002\u8fd9\u79cd\u98ce\u9669\u76f4\u63a5\u5173\u7cfb\u5230\u8f6c\u5316\u7684\u6210\u529f\u7387\u4ee5\u53ca\u5bf9\u79d1\u7814\u6210\u679c\u7684\u5b9a\u4ef7\u95ee\u9898\uff0c\u9700\u8981\u5efa\u7acb\u9002\u5f53\u7684\u673a\u5236\u6765\u4fc3\u8fdb\u6709\u4ef7\u503c\u79d1\u7814\u6210\u679c\u7684\u5feb\u901f\u8f6c\u5316\uff0c\u63d0\u5347\u6210\u529f\u7387\uff0c\u4f46\u76ee\u524d\u5728\u5177\u4f53\u6267\u884c\u5c42\u9762\u4e0a\u4ecd\u7136\u5b58\u5728\u5f88\u591a\u653f\u7b56\u7f3a\u5931\u3002<\/div>\n
\u00a0<\/div>\n
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\u00a0<\/div>\n
\u56db\u3001\u7a00\u6709\u80bf\u7624\u7ec6\u80de\u7ec6\u80de\u9274\u5b9a\u4e0e\u5355\u7ec6\u80de\u6d4b\u5e8f<\/div>\n
\u57fa\u56e0\u6167\uff1a\u6b23\u95fb\u60a8\u76843\u670831\u65e5\u5c06\u6765\u676d\u5dde\u300aNGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u4f1a\u300b\u4e0a\u505a\u4e00\u573a\u7cbe\u5f69\u7684\u5b66\u672f\u62a5\u544a\uff0c\u53ef\u5426\u548c\u57fa\u56e0\u6167\u8bfb\u8005\u7565\u8c08\u8c08\u5728\u5927\u4f1a\u4e0a\u60a8\u5373\u5c06\u6f14\u8bb2\u7684\u4e3b\u9898\u5462\uff1f\u4e0e\u60a8\u5728\u4eca\u5e742\u6708\u5728\u300a\u7f8e\u56fd\u79d1\u5b66\u9662\u9662\u520a\u300b\uff08PNAS\uff09\u53d1\u8868\u7684\u8bba\u6587\u662f\u5426\u6709\u5173\uff1f<\/div>\n
\u65bd\u6559\u6388\uff1a\u6211\u7684\u62a5\u544a\u4e3b\u9898\u4e3b\u8981\u662f\u5173\u4e8e\u4f53\u6db2\u4e2d\u7a00\u6709\u80bf\u7624\u7ec6\u80de\u7684\u9274\u5b9a\u4e0e\u5355\u7ec6\u80de\u6d4b\u5e8f\u7684\uff0c\u5176\u4e2d\u5f53\u7136\u5c31\u5305\u62ec\u5916\u5468\u8840\u4e2d\u7a00\u6709\u7684\u5faa\u73af\u80bf\u7624\u7ec6\u80de\uff08CTC\uff09\u3002\u6211\u662f\u57282013\u5e74\u8fdb\u5165CTC\u8fd9\u4e2a\u9886\u57df\u7684\uff0c\u56e0\u4e3a\u6211\u4e4b\u524d\u662f\u505a\u5355\u7ec6\u80de\u5206\u6790\u7684\uff0c\u81ea\u7136\u5c31\u4f1a\u5173\u5fc3\u90a3\u4e9b\u5177\u6709\u91cd\u8981\u751f\u7269\u5b66\u610f\u4e49\u548c\u4e34\u5e8a\u4ef7\u503c\u7684\u7a00\u6709\u7ec6\u80de\uff0c\u56e0\u4e3a\u5b83\u4eec\u6570\u91cf\u7a00\u5c11\uff0c\u56e0\u6b64\u5c31\u9700\u8981\u5355\u7ec6\u80de\u7cbe\u5ea6\u7684\u68c0\u6d4b\u65b9\u6cd5\u3002<\/div>\n
\u6211\u8fdb\u5165CTC\u8fd9\u4e2a\u9886\u57df\u7684\u65f6\u5019\u5b83\u5df2\u7ecf\u975e\u5e38\u70ed\u4e86\uff0c\u5c24\u5176\u4f34\u968f\u5f3a\u751f\u516c\u53f8\u7684CellSearch\u7cfb\u7edf2012\u5e74\u5728\u56fd\u5185\u7684\u83b7\u6279\u53ef\u4ee5\u8bf4\u5728\u968f\u540e\u51e0\u5e74\u91cc\u8fbe\u5230\u4e86\u4e00\u4e2a\u9ad8\u6f6e\u3002\u6211\u9996\u5148\u7814\u7a76\u4e86\u5df2\u6709\u7684\u4e00\u4e9b\u6280\u672f\uff0c\u7136\u540e\u6211\u53d1\u73b0\u8fd9\u4e2a\u9886\u57df\u91cc\u6709\u4e24\u4e2a\u5173\u952e\u6027\u7684\u95ee\u9898\u4e00\u76f4\u6ca1\u6709\u5f97\u5230\u89e3\u51b3\u3002<\/div>\n
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\u00a0<\/div>\n
CTC\u9886\u57df\u7684\u7b2c\u4e8c\u4e2a\u5173\u952e\u6027\u7684\u95ee\u9898\u662f\u80bf\u7624\u7ec6\u80de\u51fa\u73b0\u5728\u8840\u6db2\u4e2d\u5230\u5e95\u6709\u4ec0\u4e48\u660e\u786e\u7684\u4e34\u5e8a\u610f\u4e49\uff1f\u5f53\u7136\uff0cCTC\u63d0\u4f9b\u4e86\u80bf\u7624\u7ec4\u7ec7\u7684\u6750\u6599\uff0c\u80fd\u591f\u4f7f\u6211\u4eec\u901a\u8fc7\u5b83\u6765\u4e86\u89e3\u80bf\u7624\u7ec4\u7ec7\u7684\u5206\u5b50\u7279\u5f81\uff0c\u4ece\u800c\u6307\u5bfc\u7528\u836f\uff0c\u8fd9\u4e00\u70b9\u662f\u6bd4\u8f83\u660e\u786e\u3002\u4f46\u66f4\u4e3a\u91cd\u8981\u7684\u662f\uff0cCTC\u64ad\u6563\u8fdb\u5165\u8840\u6db2\u5faa\u73af\u7cfb\u7edf\uff0c\u5176\u4e0e\u8f6c\u79fb\u4e4b\u95f4\u7684\u5173\u7cfb\u662f\u672a\u77e5\u7684\uff0c\u4e5f\u5c31\u662f\u8bf4CTC\u7684\u51fa\u73b0\u610f\u5473\u7740\u8fdc\u5904\u8f6c\u79fb\u5df2\u7ecf\u5b8c\u6210\u8fd8\u662f\u5c1a\u672a\u5b8c\u6210\u8fd9\u4e00\u70b9\u662f\u672a\u77e5\u7684\uff0c\u4e5f\u662f\u4e34\u5e8a\u533b\u751f\u6700\u5e0c\u671b\u4e86\u89e3\u3001\u6700\u611f\u5174\u8da3\u7684\u3002\u6211\u4eec\u77e5\u9053\u7edd\u5927\u591a\u6570\u80bf\u7624\u60a3\u8005\u6b7b\u4e8e\u8f6c\u79fb\uff0c\u4e34\u5e8a\u4e0a\u5f88\u591a\u60a3\u8005\u5728\u63a5\u53d7\u624b\u672f\u540e\u77ed\u65f6\u95f4\u5185\u5c31\u51fa\u73b0\u8f6c\u79fb\u590d\u53d1\uff0c\u800c\u5f71\u50cf\u5b66\u65b9\u6cd5\u53c8\u96be\u4ee5\u53d1\u73b0\u9690\u79d8\u7684\u8f6c\u79fb\u75c5\u7076\uff0c\u56e0\u6b64\u4e34\u5e8a\u533b\u751f\u5e0c\u671b\u80fd\u591f\u901a\u8fc7\u6db2\u4f53\u6d3b\u68c0\u7684\u65b9\u5f0f\u53d1\u73b0\u8f6c\u79fb\u7684\u86db\u4e1d\u9a6c\u8ff9\u3002\u540c\u6837\u51fa\u73b0\u5728\u8840\u6db2\u4e2d\u7684ctDNA\u96be\u4ee5\u533a\u5206\u5176\u6765\u81ea\u539f\u53d1\u75c5\u7076\u8fd8\u662f\u8f6c\u79fb\u75c5\u7076\uff0c\u56e0\u6b64CTC\u7684\u68c0\u6d4b\u88ab\u5bc4\u4e8e\u5f88\u5927\u7684\u5e0c\u671b\uff0c\u56e0\u4e3a\u81f3\u5c11\u5728\u8840\u6db2\u4e2d\u68c0\u6d4b\u5230CTC\u610f\u5473\u7740\u80bf\u7624\u6709\u8f6c\u79fb\u7684\u503e\u5411\u3002\u4f46\u6b63\u5982\u6211\u4eec\u524d\u9762\u6240\u8bf4\uff0c\u524d\u63d0\u662f\u51c6\u786e\u53ef\u9760\u7684\u68c0\u6d4b\u5230CTC\u3002<\/div>\n
\u6211\u4eec\u8bfe\u9898\u7ec4\u7684\u7814\u7a76\u4e3b\u8981\u56f4\u7ed5\u4e0a\u8ff0\u4e24\u4e2a\u95ee\u9898\u8fdb\u884c\uff0c\u5373\u9996\u5148\u5982\u4f55\u786e\u8ba4\u80bf\u7624\u7ec6\u80de\uff0c\u5176\u6b21\u63a2\u7d22CTC\u4e0e\u8f6c\u79fb\u6216\u8005\u8bf4\u60a3\u8005\u4e34\u5e8a\u7ed3\u5c40\u7684\u5173\u7cfb\uff0c\u76ee\u524d\u5728\u7b2c\u4e00\u4e2a\u95ee\u9898\u65b9\u9762\u5df2\u7ecf\u53d6\u5f97\u4e86\u4e00\u4e9b\u521d\u6b65\u7684\u7ed3\u679c\u3002\u5bf9\u4e8e\u5728\u4f20\u7edf\u7684\u5f62\u6001\u5b66\u68c0\u67e5\u4e4b\u5916\u63a2\u7d22\u5feb\u901f\u3001\u7b80\u4fbf\u7684\u7a00\u6709\u6076\u6027\u7ec6\u80de\u9274\u5b9a\u65b0\u65b9\u6cd5\u3002\u7f8e\u56fd\u9ebb\u7701\u7406\u5de5\u5b66\u9662\u7684Robert A. Weinberg\u6559\u6388\u57282011\u5e74\u603b\u7ed3\u4e86\u80bf\u7624\u7ec6\u80de\u7684\u5341\u5927\u57fa\u672c\u7279\u5f81[4]\uff0c\u5305\u62ec\u7ef4\u6301\u589e\u6b96\u4fe1\u53f7\uff0c\u9003\u907f\u751f\u957f\u6291\u5236\uff0c\u6291\u5236\u7ec6\u80de\u6b7b\u4ea1\uff0c\u65e0\u9650\u81ea\u6211\u590d\u5236\uff0c\u8bf1\u5bfc\u8840\u7ba1\u751f\u6210\uff0c\u6fc0\u6d3b\u6d78\u6da6\u8f6c\u79fb\uff0c\u907f\u514d\u514d\u75ab\u635f\u4f24\uff0c\u4fc3\u8fdb\u80bf\u7624\u708e\u75c7\uff0c\u80fd\u91cf\u4ee3\u8c22\u5f02\u5e38\u4ee5\u53ca\u57fa\u56e0\u7ec4\u4e0d\u7a33\u5b9a\u7b49\u3002\u8fd9\u4e9b\u57fa\u672c\u7279\u5f81\u80fd\u591f\u6709\u6548\u5730\u9274\u522b\u6076\u6027\u7ec6\u80de\uff0c\u4f46\u5176\u4e2d\u9664\u4e86\u80fd\u91cf\u4ee3\u8c22\u5f02\u5e38\u5916\uff0c\u5176\u4ed6\u7279\u5f81\u5747\u96be\u4ee5\u65b9\u4fbf\u5730\u5728\u5355\u7ec6\u80de\u5c3a\u5ea6\u4e0a\u8fdb\u884c\u9ad8\u901a\u91cf\u7684\u68c0\u6d4b\u3002<\/div>\n\n
\n
\"eicZhoGYCfyaict3PdnQoksESCUl9yvAGYvE2tmT1gTP3YTVWUE3qGY7P1qNbPkMa9ia8gyxnphndAuD3bcibJE2rA\"\/<\/figure><\/div>\n\n<\/div>\n
\u56fe\uff1aThe Hallmarks of Cancer\uff0c\u6765\u6e90\u4e8e\u53c2\u8003\u6587\u732e[4]<\/div>\n
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\u80bf\u7624\u7ec6\u80de\u5177\u6709\u4e0d\u540c\u4e8e\u6b63\u5e38\u7ec6\u80de\u7684\u80fd\u91cf\u4ee3\u8c22\u9014\u5f84\uff0c\u8fd9\u4e00\u73b0\u8c61\u9996\u5148\u88abOtto Warburg\u89c2\u5bdf\u5230\u3002\u5373\u4f7f\u5728\u6c27\u6c14\u5b58\u5728\u7684\u60c5\u51b5\u4e0b\uff0c\u80bf\u7624\u7ec6\u80de\u4ecd\u4e3b\u8981\u4ee5\u7cd6\u9175\u89e3\u7684\u65b9\u5f0f\u8fdb\u884c\u80fd\u91cf\u4ee3\u8c22\uff0c\u5176\u6444\u53d6\u7684\u8461\u8404\u7cd6\u5927\u5927\u9ad8\u4e8e\u6b63\u5e38\u7ec6\u80de\uff0c\u8fd9\u4e00\u6548\u5e94\u88ab\u79f0\u4e3aWarburg\u6548\u5e94\uff0cWarburg\u4e5f\u56e0\u6b64\u83b7\u5f971931\u5e74\u7684\u8bfa\u8d1d\u5c14\u5956\u3002<\/div>\n
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\"eicZhoGYCfyaict3PdnQoksESCUl9yvAGYWOXM2GUUcIZ58jzgCH8zOxibJo4Mb5Ff2edMn9alXyTySqP0WQwSlHw\"\/<\/figure><\/div>\n\n<\/div>\n
\u56fe\uff1aThe Warburg Effect\uff0c\u6765\u6e90\u81ea\uff1aThe Charlie Foundation<\/div>\n
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Warburg\u6548\u5e94\u5728\u4e34\u5e8a\u4e0a\u5df2\u6709\u5e7f\u6cdb\u5e94\u7528\uff0c\u901a\u8fc7\u5c06\u5e26\u6709\u653e\u5c04\u6027\u6807\u8bb0\u7684\u8461\u8404\u7cd6\u7c7b\u4f3c\u7269\uff0818F- FDG\uff09\u4f5c\u4e3a\u793a\u8e2a\u5242\uff0c\u5e94\u7528\u6b63\u7535\u5b50\u53d1\u5c04\u65ad\u5c42\u6444\u5f71\u672f\uff08PET\/CT\uff09\u53ef\u4ee5\u975e\u4fb5\u88ad\u6027\u3001\u53ef\u89c6\u5316\u7075\u654f\u68c0\u6d4b\u4f53\u5185\u9ad8\u8461\u8404\u7cd6\u6444\u53d6\u7684\u6076\u6027\u7ec4\u7ec7\uff0c\u4ece\u800c\u53d1\u73b0\u80bf\u7624\u539f\u4f4d\u53ca\u8f6c\u79fb\u75c5\u7076\u3002\u7531\u4e8e\u653e\u5c04\u6027\u6807\u8bb0\u7684\u8461\u8404\u7cd6\u7c7b\u4f3c\u7269\u7684\u7a7a\u95f4\u5206\u8fa8\u7387\u8f83\u4f4e\uff0c\u8be5\u7814\u7a76\u91c7\u7528\u8367\u5149\u6807\u8bb0\u7684\u8461\u8404\u7cd6\u7c7b\u4f3c\u7269\u5728\u4f53\u5916\u5bf9\u5927\u91cf\u7ec6\u80de\u7684\u8461\u8404\u7cd6\u6444\u53d6\u80fd\u529b\u8fdb\u884c\u9ad8\u901a\u91cf\u68c0\u6d4b\u3002\u5176\u57fa\u672c\u5047\u8bbe\u662f\u5728\u80f8\u6c34\u6837\u672c\u4e2d\u9ad8\u8461\u8404\u7cd6\u6444\u53d6\u4e14\u4e0d\u8868\u8fbe\u767d\u7ec6\u80de\u5171\u540c\u6297\u539f\uff08CD45\uff09\u7684\u7ec6\u80de\u6709\u8f83\u5927\u53ef\u80fd\u662f\u80bf\u7624\u7ec6\u80de\uff0c\u5177\u6709\u8fd9\u7c7b\u7ec6\u80de\u7684\u80f8\u6c34\u53ef\u88ab\u9274\u5b9a\u4e3a\u6076\u6027\u80f8\u6c34\u3002\u4e3a\u4e86\u9a8c\u8bc1\u8fd9\u4e9b\u7ec6\u80de\u662f\u5426\u7684\u786e\u4e3a\u80bf\u7624\u7ec6\u80de\uff0c\u4f7f\u7528\u663e\u5fae\u64cd\u4f5c\u8bbe\u5907\u5c06\u8fd9\u4e9b\u7591\u4f3c\u80bf\u7624\u7ec6\u80de\u4e00\u4e00\u53d6\u51fa\u8fdb\u884c\u5355\u7ec6\u80de\u6d4b\u5e8f\u3002\u5b9e\u9a8c\u7ed3\u679c\u8868\u660e\uff0c\u5bf9\u4e8e\u80ba\u817a\u764c\u60a3\u8005\u7684\u80f8\u6c34\u6837\u672c\uff0c\u8d85\u8fc760%\u7684\u7591\u4f3c\u80bf\u7624\u7ec6\u80de\u5747\u68c0\u6d4b\u5230\u4e86\u4e0e\u539f\u4f4d\u80bf\u7624\u7ec6\u80de\u4e00\u81f4\u7684\u9a71\u52a8\u57fa\u56e0\u7a81\u53d8\uff08EGFR\u3001KRAS\u7b49\uff09\u3002\u540c\u65f6\uff0c\u5728\u90e8\u5206\u4f20\u7edf\u7ec6\u80de\u5b66\u68c0\u67e5\u9634\u6027\u6216\u65e0\u6cd5\u786e\u8bca\u7684\u6837\u672c\u4e2d\uff0c\u8be5\u65b9\u6cd5\u80fd\u591f\u6709\u6548\u627e\u5230\u80bf\u7624\u7ec6\u80de\u5e76\u901a\u8fc7\u6d4b\u5e8f\u52a0\u4ee5\u786e\u8ba4\u3002<\/div>\n
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\u5728\u80f8\u6c34\u6837\u672c\u4e2d\u68c0\u6d4b\u9ad8\u4ee3\u8c22\u6d3b\u6027\u7684\u7ec6\u80de\u662f\u4e00\u79cd\u5feb\u901f\u9274\u5b9a\u6076\u6027\u80f8\u6c34\u7684\u6709\u6548\u65b9\u6cd5\uff0c\u6709\u671b\u6210\u4e3a\u73b0\u6709\u7ec6\u80de\u5b66\u68c0\u67e5\u7684\u6709\u76ca\u8865\u5145\u3002\u8be5\u65b9\u6cd5\u7b5b\u9009\u5230\u7684\u9ad8\u4ee3\u8c22\u6d3b\u6027\u7ec6\u80de\u5747\u5177\u6709\u9ad8\u5ea6\u6d3b\u6027\uff0c\u56e0\u6b64\u80fd\u65b9\u4fbf\u5730\u8fdb\u884c\u5355\u7ec6\u80de\u6d4b\u5e8f\u4e0e\u4f53\u5916\u57f9\u517b\u3002\u8fdb\u4e00\u6b65\u7684\u5b9e\u9a8c\u8868\u660e\uff0c\u8be5\u65b9\u6cd5\u53ef\u88ab\u5e94\u7528\u4e8e\u8840\u6db2\u6837\u672c\u4e2d\u5faa\u73af\u80bf\u7624\u7ec6\u80de\u7684\u68c0\u6d4b\uff0c\u4f46\u7531\u4e8e\u8840\u6db2\u4e2d\u7684\u7ec6\u80de\u6570\u76ee\u8fdc\u591a\u4e8e\u80f8\u6c34\uff0c\u68c0\u6d4b\u65f6\u95f4\u4e5f\u9700\u76f8\u5e94\u5ef6\u957f\u3002\u8be5\u7814\u7a76\u901a\u8fc7\u80bf\u7624\u7ec6\u80de\u7684\u80fd\u91cf\u4ee3\u8c22\u5f02\u5e38\u8fd9\u4e00\u57fa\u672c\u7279\u5f81\u5728\u4f53\u6db2\u6837\u672c\u4e2d\u9ad8\u901a\u91cf\u3001\u5feb\u901f\u9274\u5b9a\u80bf\u7624\u7ec6\u80de\uff0c\u5e76\u901a\u8fc7\u5927\u91cf\u7684\u5355\u7ec6\u80de\u6d4b\u5e8f\u786e\u8ba4\u5176\u53ef\u9760\u6027\uff0c\u63d0\u4f9b\u4e86\u4e00\u79cd\u5728\u590d\u6742\u4f53\u6db2\u6837\u672c\u4e2d\u9274\u5b9a\u6076\u6027\u7ec6\u80de\u7684\u65b0\u601d\u8def\u548c\u65b0\u65b9\u6cd5\u3002<\/div>\n
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\uff08\u53c2\u8003\u6587\u732e\u5217\u8868\u89c1\u6587\u7ae0\u5e95\u90e8\uff09<\/div>\n
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\u300a\u7b2c\u56db\u5c4aNGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u4f1a\u300b<\/div>\n
\u57fa\u56e0\u6167\u9996\u6b21\u8054\u5408\u627f\u529e\u5e76\u68b3\u7406\u57fa\u56e0\u884c\u4e1a\u9ec4\u91d1\u5341\u5e74<\/div>\n
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\"eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9UhTna42RXpq6FwmGGTF4icLicQ03atjZz1lvvMBsmPmibRSq7icT4DTl4A\"\/<\/figure><\/div>\n\n<\/div>\n
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\"eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9IIxibyKp3IwZ4t5xHG6AHsTf78c76RVLdWicwM1FElyNVaow5qPGEG1g\"\/<\/figure><\/div>\n\n<\/div>\n
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\u300a\u7b2c\u56db\u5c4aNGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u4f1a\u300b\u7cbe\u5f69\u9884\u544a<\/div>\n
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\u65f6\u95f4<\/div>\n
\u5185\u5bb9<\/div>\n
\u5609\u5bbe<\/div>\n
\u4e0a\u5348 \u4e28 NGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u4f1a<\/div>\n
08:00-09:00<\/div>\n
\u5927\u4f1a\u7b7e\u5230<\/div>\n
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\u4e3b\u6301\u4eba\u5f00\u573a<\/div>\n
09:10-09:15<\/div>\n
\u4e3b\u529e\u65b9\u81f4\u8f9e<\/div>\n
\u4e3b\u529e\u65b9<\/div>\n
09:15-09:20<\/div>\n
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\u653f\u5e9c\u9886\u5bfc<\/div>\n
09:20-09:45<\/div>\n
Single Molecule Electronic DNA Sequencing by Synthesis Using Tagged Nucleotides and Nanopore Detection<\/div>\n
\u97a0\u666f\u6708 \u6559\u6388<\/div>\n
Center for Genome Technology and Biomolecular Engineering, Departments of Chemical Engineering and Pharmacology, Columbia University<\/div>\n
09:45-10:10<\/div>\n
\u7a33\u5b9a\u9ad8\u6548\u7684\u65b0\u578b\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u5206\u5b50MspA<\/div>\n
\u5218\u5168\u4fca \u6559\u6388<\/div>\n
\u4e1c\u5357\u5927\u5b66<\/div>\n
10:10-10:35<\/div>\n
\u57fa\u4e8e\u9ad8\u901a\u91cf\u6d4b\u5e8f\u7684\u7cfb\u7edf\u89e3\u51b3\u65b9\u6848<\/div>\n
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\u534e\u5927\u667a\u9020\u4eea\u5668\u5f00\u53d1\u603b\u76d1<\/div>\n
10:35-11:00<\/div>\n
\u667a\u80fd\u52a0\u6837\u9ad8\u901a\u91cf\u5355\u5206\u5b50\u57fa\u56e0\u7ec4\u7ed3\u6784\u53d8\u5f02\u68c0\u6d4b\u5e73\u53f0Saphyr<\/div>\n
\u66f9\u6db5 \u535a\u58eb<\/div>\n
Bionano\u521b\u59cb\u4eba\u517c\u9996\u5e2d\u79d1\u5b66\u5bb6<\/div>\n
11:00-11:25<\/div>\n
\u4f53\u6db2\u6837\u672c\u4e2d\u9ad8\u901a\u91cf\u7a00\u6709\u5355\u7ec6\u80de\u81ea\u52a8\u5206\u79bb\u4e0e\u5355\u7ec6\u80de\u6d4b\u5e8f\u5e94\u7528<\/div>\n
\u65bd\u5947\u60e0 \u6559\u6388<\/div>\n
\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66<\/div>\n
11:25-11:40<\/div>\n
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11:40-13:00<\/div>\n
\u5348\u9910<\/div>\n
\u4e0b\u5348 \u4e28 NGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u4f1a<\/div>\n
13:00-13:15<\/div>\n
\u4e3b\u6301\u4eba\u5f00\u573a<\/div>\n
13:15-13:40<\/div>\n
Universal Haplotype-Based Noninvasive Prenatal Testing for Single Gene Diseases (\u5355\u57fa\u56e0\u75be\u75c5\u65e0\u521b\u8bca\u65ad\u7684\u901a\u7528\u65b9\u6cd5)<\/div>\n
\u6c5f\u57f9\u52c7 \u6559\u6388<\/div>\n
\u9999\u6e2f\u4e2d\u6587\u5927\u5b66<\/div>\n
13:40-14:05<\/div>\n
\u4e0d\u4f9d\u8d56\u9ad8\u901a\u91cf\u6d4b\u5e8f\u7684\u65e0\u521b\u4ea7\u524dNIPT<\/div>\n
\u5218\u8d85 \u535a\u58eb<\/div>\n
\u5929\u660a\u751f\u7269\u533b\u836f\uff08\u82cf\u5dde\uff09\u6709\u9650\u516c\u53f8\u9996\u5e2d\u79d1\u5b66\u5bb6<\/div>\n
14:05-14:30<\/div>\n
\u5168\u57fa\u56e0\u7ec4cfDNA\u667a\u80fd\u6570\u636e\u5206\u6790\u5728\u764c\u75c7\u65e9\u671f\u7b5b\u9009\u4e2d\u7684\u5e94\u7528<\/div>\n
\u6768\u864e\u5c71 \u535a\u58eb<\/div>\n
\u8d39\u57ceThomas Jefferson\u5927\u5b66Sidney Kimmel\u764c\u75c7\u4e2d\u5fc3<\/div>\n
14:30-14:45<\/div>\n
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14:45-15:10<\/div>\n
\u57fa\u4e8eDNA\u7532\u57fa\u5316\u7684\u9ad8\u7075\u654f\u5ea6\u80bf\u7624\u6db2\u4f53\u6d3b\u68c0<\/div>\n
\u5218\u854a \u535a\u58eb<\/div>\n
\u4e0a\u6d77\u9e4d\u8fdc\u57fa\u56e0CTO<\/div>\n
15:10-15:35<\/div>\n
\u57fa\u4e8e\u5faa\u73af\u80bf\u7624DNA\u7684\u80bf\u7624\u65e9\u671f\u68c0\u6d4b<\/div>\n
\u5218\u671d\u715c \u535a\u58eb<\/div>\n
\u6df1\u5733\u56e0\u5408\u751f\u7269CEO<\/div>\n
15:35-16:00<\/div>\n
\u5bfb\u627e\u7b2c\u4e8c\u4ee3\u4e2a\u4eba\u57fa\u56e0\u7ec4\u4ea7\u54c1\u6210\u529f\u4e4b\u8def<\/div>\n
\u5f90\u5174 \u535a\u58eb<\/div>\n
Genos\u521b\u4e16\u56e2\u961f\u6210\u5458\u3001\u751f\u7269\u4fe1\u606f\u4ea7\u54c1\u603b\u76d1<\/div>\n
16:00-16:25<\/div>\n
\u533b\u7597\u5065\u5eb7\u521b\u65b0\u4e0e\u843d\u5730—\u57fa\u56e0\u4e0e\u8868\u578b\u7684\u8fde\u63a5<\/div>\n
\u987e\u536b\u7ea2 \u535a\u58eb<\/div>\n
\u4e2d\u65e5\u533b\u9662\u8fd0\u52a8\u969c\u788d\u4e0e\u795e\u7ecf\u9057\u4f20\u75c5\u7814\u7a76\u4e2d\u5fc3\u8d1f\u8d23\u4eba\u3001CHPO\u603b\u534f\u8c03\u4eba<\/div>\n
16:25-16:50<\/div>\n
\u9ec4\u91d1\u5341\u5e74\u2014\u2014\u56fd\u5185\u5916\u57fa\u56e0\u4f01\u4e1a\u5e03\u5c40\u68b3\u7406<\/div>\n
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\u57fa\u56e0\u6167\u521b\u59cb\u4eba\u517cCEO<\/div>\n
16:50-17:35<\/div>\n
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\u5609\u5bbe\u656c\u8bf7\u671f\u5f85<\/div>\n
17:35-18:00<\/div>\n
\u5927\u4f1a\u4e3b\u8bae\u7a0b\u7ed3\u675f\uff0c\u5609\u5bbe\u5408\u5f71<\/div>\n
\u665a\u4e0a | \u541b\u8054-NGS\u521b\u65b0\u5f00\u53d1\u8005\u4e4b\u591c\uff08\u665a\u5bb4\uff09<\/div>\n
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\u4e3b\u6301\u4eba\u5f00\u573a<\/div>\n
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\u4e3b\u529e\u65b9\u81f4\u8f9e<\/div>\n
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18:20-18:40<\/div>\n
\u665a\u5bb4\u795d\u9152\u8f9e<\/div>\n
\u541b\u8054\u8d44\u672c<\/div>\n
18:40-19:00<\/div>\n
\u4e3b\u9898\u6f14\u8bb2\uff08\u4e13\u4e1a\u9886\u57df\uff09<\/div>\n
\u738b\u5b66\u521a<\/div>\n
\u8d1d\u58f3\u793e\u521b\u59cb\u5408\u4f19\u4eba<\/div>\n
19:00-19:20<\/div>\n
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\u6811\u5170\u533b\u7597\u4ea7\u4e1a\u57fa\u91d1<\/div>\n
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\u534f\u4f1a\u6587\u827a\u4ee3\u8868<\/div>\n
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\u9881\u53d1NGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u5956<\/div>\n
19:40-19:50<\/div>\n
\u4e3b\u9898\u6f14\u8bb2\uff08\u6295\u8d44\u5206\u6790\uff09<\/div>\n
\u666e\u534e\u8d44\u672c<\/div>\n
19:50-20:00<\/div>\n
\u4e3b\u9898\u6f14\u8bb2\uff08\u884c\u4e1a\u5206\u6790\uff09<\/div>\n
\u4e1c\u65b9\u8bc1\u5238<\/div>\n
20:00-20:15<\/div>\n
\u4e3b\u9898\u6f14\u8bb2\uff08\u884c\u4e1a\u62a5\u544a\uff09<\/div>\n
\u5609\u5bbe\u656c\u8bf7\u671f\u5f85<\/div>\n
20:15-20:30<\/div>\n
\u81ea\u7531\u4ea4\u6d41<\/div>\n
\uff08\u6ce8\uff1a\u4ee5\u5f53\u5929\u65e5\u7a0b\u4e3a\u4e3b\uff09<\/div>\n
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\u53c2\u8003\u6587\u732e\u8d44\u6599\uff1a<\/div>\n
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1.Wei W*, Shi QH*, Remacle F*, Qin LD, Shackelford D, Shin YS, Mischel, PS, Levine RD, Heath JR, \u201cHypoxia Induces a Phase Transition within a Kinase Signaling Network in Cancer Cells\u201d, Proc. Natl. Acad. Sci. USA 2013, 110, E1352<\/div>\n
2. Shi QH, Qin LD, Wei W, Geng F, Fan R, Shin YS, Guo DL, Hood L, Mischel PS, Heath JR, \u201cSingle-cell proteomic chips for profiling intracellular signaling pathways in single tumor cells\u201d, Proc. Natl. Acad. Sci. USA 2012, 109, 419<\/div>\n
3.Ma C, Fan R, Ahmad H, Shi QH, Comin-Anduix B, Chodon T, Koya, RC, Liu CC, Kwong GA, Radu CG, Ribas A, Heath JR, \u201cA clinical microchip for evaluation of single immune cells reveals high functional heterogeneity in phenotypically similar T cells\u201d, Nat. Med. 2011, 17, 738.<\/div>\n
4.Hanahan, D.; Weinberg, R.A. Hallmarks of cancer: The next generation. Cell 2011, 144, 646\u2013674, doi:10.1016\/j.cell.2011.02.013.<\/div>\n
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Connection is power<\/div>\n
\u57fa\u56e0\u6167 GeneClub<\/div>\n
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\u6bcf\u65e5\u56fd\u5185\u5916\u7cbe\u51c6\u533b\u7597\u8d44\u8baf\uff1a\u300aGeneMail\u300b<\/div>\n
\u6bcf\u5468\u6df1\u5ea6\u91c7\u8bbf\u884c\u4e1a\u5927\u5496\uff1a\u300a\u5927\u5496\u8bba\u5065\u300b<\/div>\n
\u6bcf\u6708\u5f55\u5236\u884c\u4e1a\u4e09\u4eba\u8c08\uff1a\u300a\u57fa\u56e0\u4e09\u4eba\u884c\u300b<\/div>\n
\u6bcf\u5b63\u5ea6\u51fa\u884c\u4e1a\u62a5\u544a\uff1a\u300a\u6167\u773c\u7814\u7a76\u300b<\/div>\n
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1. \u4ee5\u4e0a\u5185\u5bb9\u662f\u57fa\u56e0\u6167\u72ec\u7acb\u7b56\u5212\u3001\u7f16\u8f91\u6210\u6587\u3002\u7248\u6743\u5c5e\u4e8e\u57fa\u56e0\u6167\uff0c\u5728\u5c0a\u91cd\u7248\u6743\u60c5\u51b5\u4e0b\uff0c\u6b22\u8fce\u8f6c\u53d1\u3002\u8f6c\u8f7d\u8bf7\u6ce8\u660e\uff1a\u6765\u6e90\u4e8e\u57fa\u56e0\u6167\u3002<\/div>\n
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