\u65bd\u5947\u60e0 \u6559\u6388<\/div>\n
<\/div>\n
<\/div>\n
\u5173\u952e\u8bcd\uff1a\u764c\u75c7\u65e9\u7b5b\u5efa\u6a21 cfDNA<\/div>\n
\u5927\u6570\u636e\u667a\u80fd\u5206\u6790 miRNA\u751f\u7269\u6807\u8bb0<\/div>\n
\u5efa\u8bae\u7528\u65f6\uff1a7\u5206\u949f<\/div>\n
<\/div>\n
<\/div>\n
\n\n
\n![\"eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe90Lrgia8pSqaDzFS42OHcyLs6BXFciaUOrtsBhZO7Mk0XksIZjd9cRZCA\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe90Lrgia8pSqaDzFS42OHcyLs6BXFciaUOrtsBhZO7Mk0XksIZjd9cRZCA.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u7cbe\u51c6\u533b\u5b66\uff0c\u662f\u79d1\u5b66\u6280\u672f\u5316\u3001\u6280\u672f\u4ea7\u4e1a\u5316\u7684\u9886\u57df\u3002\u5b83\u56f4\u7ed5\u57fa\u56e0\u6280\u672f\u3001\u5fae\u751f\u7269\u7ec4\u3001\u514d\u75ab\u6cbb\u7597\u3001\u5927\u6570\u636e\u3001\u4eba\u5de5\u667a\u80fd\u7b49\u8f85\u52a9\u533b\u5b66\u4fe1\u606f\u5316\uff0c\u4e3a\u6d77\u91cf\u4eba\u7fa4\u63d0\u4f9b\u4e2a\u6027\u5316\u9884\u9632\u548c\u8bca\u7597\uff0c\u662f\u7ee7\u8f6c\u5316\u533b\u5b66\u540e\u7684\u5347\u7ea7\u3002\u56fd\u5bb6\u6218\u7565\u3001\u79d1\u7814\u53d1\u5c55\u3001\u4ea7\u4e1a\u5174\u8d77\u628a\u7cbe\u51c6\u533b\u5b66\u63a8\u5411\u6d6a\u5c16\uff0c\u540c\u65f6\u5728\u89c4\u8303\u6807\u51c6\u3001\u653f\u7b56\u5f15\u5bfc\u3001\u79d1\u5b66\u666e\u53ca\u3001\u8d44\u6e90\u6574\u5408\u4e0a\u4ecd\u5b58\u5728\u5927\u91cf\u4fe1\u606f\u4e0d\u5bf9\u79f0\u3002<\/div>\n
\u201c\u4f7f\u8fde\u63a5\u4ea7\u751f\u4ef7\u503c\uff0c\u8ba9\u77e5\u8bc6\u83b7\u5f97\u5c0a\u91cd\u201d\u4f5c\u4e3a\u7cbe\u51c6\u533b\u5b66\u884c\u4e1a\u53d8\u9769\u7684\u8fde\u63a5\u5668\uff0c\u57fa\u56e0\u6167\u4e3b\u529e\u300a\u5927\u5496\u8bba\u5065\u300b\uff0c\u4e3a\u884c\u4e1a\u4ee3\u8868\u63d0\u4f9b\u4e13\u4e1a\u53d1\u58f0\u5e73\u53f0\u3002\u672c\u671f\u9080\u8bf7Sidney Kimmel \u764c\u75c7\u4e2d\u5fc3\u533b\u5b66\u80bf\u7624\u5b66\u7cfb\u6768\u864e\u5c71\u6559\u6388\u548c\u5927\u5bb6\u5206\u4eab\u57fa\u4e8e\u764c\u75c7\u65e9\u7b5b\u5efa\u6a21\u3002\u611f\u8c22NGS\u521b\u65b0\u5f00\u53d1\u8005\u534f\u4f1a\u5bf9\u672c\u671f\u6d3b\u52a8\u7684\u652f\u6301\u3002<\/div>\n
\u00a0<\/div>\n
\u6b22\u8fce\u79d1\u7814\/\u4e34\u5e8a\/\u4ea7\u4e1a\u4ee3\u8868\u53c2\u4e0e\u300a\u5927\u5496\u8bba\u5065\u300b\u3002<\/div>\n
\u6b22\u8fce\u5206\u4eab\u8f6c\u53d1\u3002\u8f6c\u8f7d\u8bf7\u8054\u7cfb\u6388\u6743\u3002<\/div>\n
\u5f80\u671f\u7cbe\u534e\u5185\u5bb9<\/div>\n
\u7ea2\u6749\u4e2d\u56fd-\u6768\u4e91\u971e<\/a> |WeGene-\u9648\u94a2<\/a> | \u7cbe\u51c6\u57fa\u56e0-\u5f20\u6d69<\/a>| \u57fa\u4e91\u60e0\u5eb7-\u90dd\u5411\u7a33<\/a>|\u9510\u7fcc\u751f\u7269-\u79e6\u6960<\/a>| \u6cdb\u751f\u5b50-\u960e\u6d77<\/a>| \u6d77\u666e\u6d1b\u65af-\u8bb8\u660e\u708e<\/a> | \u67f4\u6620\u723d<\/a> | \u601d\u8def\u8fea-\u718a\u78ca<\/a> | \u836f\u660e\u5eb7\u5fb7\u660e\u7801\u751f\u7269-\u5b59\u6d2a\u4e1a<\/a> | \u534e\u5927\u57fa\u56e0-\u5c39\u70e8<\/a>| \u9ec4\u5c1a\u5fd7<\/a> | \u4e2d\u65e5\u533b\u9662-\u987e\u536b\u7ea2<\/a> | \u897f\u5357\u533b\u9662-\u59da\u5b8f<\/a> | \u534f\u548c\u533b\u9662-\u8d75\u6d77\u6d9b<\/a> |\u590d\u65e6\u9644\u5c5e\u513f\u79d1\u533b\u9662-\u738b\u827a<\/a> |\u5317\u5927\u4e00\u9662-\u4e01\u6d01<\/a>|\u6d59\u6c5f\u5927\u5b66-\u7941\u9e23<\/a> |\u4e0a\u6d77\u513f\u7ae5\u533b\u9662-\u738b\u4f1f<\/a> |\u6e05\u534e\u5927\u5b66-\u6234\u4fca\u5f6a<\/a>|\u534e\u5927\u57fa\u56e0-\u6c88\u73a5<\/a> |\u8f9b\u8f9b\u90a3\u63d0\u513f\u7ae5\u533b\u9662-\u9ec4\u6d9b\u751f<\/a><\/div>\n
\u300a\u5927\u5496\u8bba\u5065\u300b24\u671f<\/div>\n
cfDNA\u5927\u6570\u636e\u548c\u764c\u75c7\u65e9\u7b5b<\/div>\n
\u4f5c\u8005\uff1a\u6768\u864e\u5c71 \u6559\u6388<\/div>\n
\u7f16\u8005\uff1a\u57fa\u56e0\u6167<\/div>\n\n
\n![\"eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9ic98kaQrajuhL1cL9u9NhN65voSEfrzYRaPQib39WFfbF0vgnksWXl5A\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9ic98kaQrajuhL1cL9u9NhN65voSEfrzYRaPQib39WFfbF0vgnksWXl5A.png\")
<\/figure><\/div>\n\n<\/div>\n
<\/figure><\/div>\n\n<\/div>\n<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
\u4e00\u3001\u4ece\u8d1d\u52d2\u533b\u5b66\u9662\u5230Sidney Kimmel\u764c\u75c7\u4e2d\u5fc3<\/div>\n
<\/div>\n
<\/div>\n
\u57fa\u56e0\u6167\uff1a\u6768\u6559\u6388\uff0c\u60a8\u597d\uff01\u611f\u8c22\u60a8\u63a5\u53d7\u57fa\u56e0\u6167\u7684\u4e13\u8bbf\u3002\u4ece\u8d1d\u52d2\u533b\u5b66\u9662\u3001\u5b89\u5fb7\u68ee\u764c\u75c7\u4e2d\u5fc3\u5230\u6258\u9a6c\u65af\u6770\u6590\u900a\u5927\u5b66\u764c\u75c7\u7814\u7a76\u4e2d\u5fc3\uff0c\u60a8\u7684\u7814\u7a76\u7ecf\u5386\u975e\u5e38\u4e30\u5bcc\uff0c\u8bf7\u60a8\u5411\u57fa\u56e0\u6167\u8bfb\u8005\u4ecb\u7ecd\u4e0b\u81ea\u5df1\u548c\u7814\u7a76\u9886\u57df\uff1f<\/div>\n
<\/div>\n
\u6768\u6559\u6388\uff1a\u5f88\u611f\u8c22\u6709\u8fd9\u4e2a\u673a\u4f1a\u53ef\u4ee5\u901a\u8fc7\u57fa\u56e0\u6167\u548c\u540c\u884c\u4ee5\u53ca\u57fa\u56e0\u6167\u7684\u8bfb\u8005\u8fdb\u884c\u4ea4\u6d41\u3002\u6211\u6bd5\u4e1a\u4e8e\u5357\u5f00\u5927\u5b66\u751f\u7269\u5316\u5b66\u7cfb\u300290\u5e74\u4ee3\u672b\u6765\u5230\u4f11\u65af\u987f\u7684\u8d1d\u52d2\u533b\u5b66\u9662\u653b\u8bfb\u5206\u5b50\u751f\u7269\u5b66\u7684\u535a\u58eb\u3002\u8bfb\u535a\u58eb\u7684\u671f\u95f4\uff0c\u6211\u63a5\u89e6\u4e86\u5927\u91cf\u764c\u75c7\u751f\u7269\u5b66\u548c\u764c\u75c7\u9057\u4f20\u5b66\u7684\u77e5\u8bc6\uff0c\u4ece\u800c\u51b3\u5b9a\u81f4\u529b\u4e8e\u505a\u764c\u75c7\u7684\u8f6c\u5316\u548c\u4e34\u5e8a\u533b\u5b66\u65b9\u9762\u7684\u7814\u7a76\u3002\u535a\u58eb\u6bd5\u4e1a\u540e\u6211\u52a0\u5165MD\u5b89\u5fb7\u68ee\u764c\u75c7\u4e2d\u5fc3\u505a\u535a\u58eb\u540e\uff0c\u901a\u8fc7\u5206\u5b50\u6d41\u884c\u75c5\u548c\u57fa\u56e0\u7ec4\u5b66\u7684\u624b\u6bb5\u6765\u5bfb\u627e\u751f\u7269\u6807\u5fd7\u7269\uff0c\u8fdb\u800c\u53d1\u5c55\u7edf\u8ba1\u6a21\u578b\u6765\u8fdb\u884c\u764c\u75c7\u7684\u98ce\u9669\u9884\u6d4b\u548c\u65e9\u671f\u7b5b\u67e5\uff0c\u4ee5\u53ca\u836f\u7269\u53cd\u5e94\uff0c\u590d\u53d1\u68c0\u6d4b\u7b49\u9884\u540e\u65b9\u9762\u7684\u7814\u7a76\u3002\u5f53\u65f6\u6211\u4eec\u7814\u7a76\u7684\u91cd\u70b9\u4e4b\u4e00\u4fbf\u662fmicroRNA\u7684\u8868\u8fbe\u548c\u9057\u4f20\u591a\u6001\u6027\u5728\u5404\u79cd\u5b9e\u4f53\u7624\u4e2d\u8d77\u5230\u7684\u98ce\u9669\u9884\u6d4b\u7684\u4f5c\u7528\u3002\u5728\u8d1d\u52d2\u533b\u5b66\u9662\u8bfb\u4e66\u7684\u7b2c\u4e00\u5e74\uff0c\u6211\u7ed3\u8bc6\u4e86\u6211\u7684\u597d\u53cb\uff0c\u4e5f\u662f\u6211\u6700\u91cd\u8981\u7684\u7814\u7a76\u4f19\u4f34\u4e4b\u4e00\uff0c\u674e\u51b0\u5c71\u6559\u6388\u3002\u674e\u6559\u6388\u662f\u7edf\u8ba1\u9057\u4f20\u5b66\u548c\u751f\u7269\u4fe1\u606f\u5b66\u7684\u4e13\u5bb6\uff0c\u73b0\u5de5\u4f5c\u4e8e\u7530\u7eb3\u897f\u7684\u8303\u5fb7\u5821\u5927\u5b66\u9057\u4f20\u4e2d\u5fc3\u3002\u6211\u4eec\u5728\u5404\u81ea\u5efa\u7acb\u72ec\u7acb\u5b9e\u9a8c\u5ba4\u4e4b\u540e\u4fbf\u5f00\u59cb\u4e86\u6781\u5176\u5e7f\u6cdb\u7684\u5728\u80bf\u7624\u7684\u6db2\u4f53\u6d3b\u68c0\u65b9\u9762\u7684\u5408\u4f5c\uff0c\u5e76\u5728\u53d1\u5c55\u8fc7\u7a0b\u4e2d\u5f97\u5230\u4e86\u7f8e\u56fd\u56fd\u7acb\u764c\u75c7\u7814\u7a76\u6240\uff0c\u56fd\u5bb6\u4eba\u7c7b\u57fa\u56e0\u7ec4\u7814\u7a76\u6240\uff0c\u7f8e\u56fd\u764c\u75c7\u534f\u4f1a\u7b49\u673a\u6784\u7684\u57fa\u91d1\u652f\u6301\u3002\u6211\u4eec\u5408\u4f5c\u7684\u91cd\u70b9\u65b9\u5411\u4e4b\u4e00\u5c31\u662f\u901a\u8fc7cfDNA\u8fdb\u884c\u4e59\u809d\u75c5\u4eba\u4e2d\u7684\u809d\u764c\u7684\u65e9\u671f\u7b5b\u67e5\u548c\u8bca\u65ad\u3002\u8fd9\u4e2a\u5408\u4f5c\u662f\u57fa\u4e8e\u6211\u5728\u6211\u5de5\u4f5c\u7684Sidney Kimmel\u764c\u75c7\u4e2d\u5fc3\u6240\u5efa\u7acb\u7684\u5927\u578b\u524d\u77bb\u6027\u548c\u7eb5\u5411\u6027\u4eba\u7fa4\u961f\u5217\uff0c\u5305\u62ec\u4e0a\u4e07\u4f8b\u7684\u4e59\u809d\uff0c\u809d\u786c\u5316\uff0c\u764c\u524d\uff0c\u548c\u65e9\u671f\u809d\u764c\u8bca\u65ad\u65f6\u7684\u8840\u6db2\u6837\u672c\u3002\u540c\u65f6\uff0c\u6211\u4eec\u7684\u5408\u4f5c\u8fd8\u6709\u76f8\u5f53\u4e00\u90e8\u5206\u7cbe\u529b\u96c6\u4e2d\u4e8e\u5faa\u73af\u80bf\u7624\u7ec6\u80de(CTC)\u5728\u764c\u75c7\u9884\u540e\u65b9\u9762\u7684\u7814\u7a76\u3002\u8fd9\u65b9\u9762\u7684\u5408\u4f5c\u8fd8\u5305\u62ec\u6211\u53e6\u5916\u7684\u4e00\u4e2a\u91cd\u8981\u5408\u4f5c\u8005\uff0cMassimo Cristofanilli\u6559\u6388\u3002Cristofanilli\u6559\u6388\u4e8e2004\u5e74\u53d1\u8868\u5728\u65b0\u82f1\u683c\u5170\u533b\u5b66\u6742\u5fd7\u4e0a\u7684\u6587\u7ae0\u76f4\u63a5\u5bfc\u81f4\u4e86FDA\u6279\u51c6\u4e86Janssen Diagnostics\u7684 CellSearch\u4eea\u5668\u7528\u4e8eCTC\u7684\u8ba1\u6570\u7528\u4e8e\u9884\u6d4b\u665a\u671f\u4e73\u817a\u764c\u7684\u9884\u540e\u3002 Cristofanilli\u6559\u6388\u57282013\u5e74\u6765\u5230Sidney Kimmel\u764c\u75c7\u4e2d\u5fc3\u51fa\u4efb\u4e73\u817a\u764c\u4e2d\u5fc3\u7684\u4e3b\u4efb\u3002\u6211\u4eec\u5408\u4f5c\u5efa\u7acb\u4e86\u4e00\u4e2a\u5927\u578b\u7684\u665a\u671f\u4e73\u817a\u764c\u7684\u75c5\u4eba\u961f\u5217\u6765\u7814\u7a76\u6db2\u4f53\u6d3b\u68c0\u5728\u75c5\u4eba\u9884\u540e\u65b9\u9762\u7684\u4f5c\u7528\u3002\u8fd1\u5e74\u6765\uff0c\u6211\u548c\u674e\u6559\u6388\uff0cCristofanilli\u6559\u6388\u5408\u4f5c\u5f00\u53d1\u4e86\u4e00\u4e2a\u4eceCTC\u6536\u96c6\u5230\u5355\u7ec6\u80deCTC\u9057\u4f20\u5206\u6790\u7684\u5168\u9762\u7684\u6d41\u7a0b\uff0c\u5e76\u4e14\u5728\u6700\u8fd1\u7684\u56fd\u7acb\u764c\u75c7\u7814\u7a76\u6240\u7684\u57fa\u91d1\u7533\u8bf7\u4e2d\u53d6\u5f97\u4e86\u6781\u9ad8\u7684\u5206\u6570\u3002\u6211\u4eec\u671f\u671b\u5c06\u6765\u53ef\u4ee5\u5c06ctDNA\u548cCTC\u7684\u57fa\u56e0\u7ec4\u5206\u6790\u7ed3\u5408\u5230\u4e00\u8d77\u800c\u53d1\u5c55\u66f4\u4e3a\u6709\u6548\u7684\u6db2\u4f53\u6d3b\u68c0\u7684\u6280\u672f\u3002<\/div>\n
<\/div>\n
\n\n
\n![\"eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9ZdD27DjrMibcHgX2DhAhuia0wMfwRmiaSuMHBp9ezzXpZHk0uwwPuhRRA\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9ZdD27DjrMibcHgX2DhAhuia0wMfwRmiaSuMHBp9ezzXpZHk0uwwPuhRRA.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe\uff1a\u6db2\u4f53\u6d3b\u68c0\u53ca\u5176\u5e94\u7528\uff0c\u56fe\u7247\u6765\u6e90\u4e8eMarc Beishon What can we learn from liquid biopsies?\uff0c\u539f\u59cb\u51fa\u5904AACR<\/div>\n
\u4e8c\u3001ctDNA\u6280\u672f\u53d1\u5c55\u548c\u764c\u75c7\u65e9\u7b5b<\/div>\n
\u57fa\u56e0\u6167\uff1a\u73b0\u5728\u5927\u5bb6\u63d0\u5230\u80bf\u7624\u7cbe\u51c6\u533b\u5b66\uff0c\u8a00\u5fc5\u8c08ctDNA\u548ccfDNA\uff0c\u53ef\u5426\u8bf7\u60a8\u7b80\u5355\u3001\u7cfb\u7edf\u5730\u5411\u4e34\u5e8a\u533b\u751f\u666e\u53ca\u4e0b\uff0c\u6db2\u4f53\u6d3b\u68c0\uff0c\u7279\u522b\u662fctDNA\u548ccfDNA\u76ee\u524d\u7684\u6280\u672f\u8fdb\u5c55\uff0c\u5e94\u7528\u5230\u4e34\u5e8a\u4e0a\u6709\u7740\u54ea\u4e9b\u6311\u6218\u548c\u524d\u666f\uff1f<\/div>\n
\u6768\u6559\u6388\uff1acfDNA\u6307\u7684\u662f\u8840\u6db2\u91cc\u7684\u5faa\u73afDNA\u7684\u603b\u548c\uff0c\u800cctDNA\u4e13\u6307\u4ece\u80bf\u7624\u6765\u6e90\u7684cfDNA\uff0c\u6240\u4ee5\u662fcfDNA\u7684\u4e00\u90e8\u5206\u3002\u57fa\u4e8ecfDNA\u7684\u6db2\u4f53\u6d3b\u68c0\u7684\u7814\u7a76\u5728\u8fd1\u51e0\u5e74\u6765\u7099\u624b\u53ef\u70ed\uff0c\u4e3b\u8981\u662f\u7531\u4e8ecfDNA\u53ef\u4ee5\u5728\u67d0\u4e9b\u7a0b\u5ea6\u4e0a\u907f\u514d\u7ec4\u7ec7\u6d3b\u68c0\u7684\u4e00\u4e9b\u672c\u8d28\u4e0a\u96be\u4ee5\u89e3\u51b3\u7684\u7f3a\u9677\u3002\u6bd4\u5982\u8bf4\uff0c\u80bf\u7624\u7684\u5f02\u8d28\u6027\uff0c\u7ec4\u7ec7\u6d3b\u68c0\u7684\u4fb5\u5165\u6027\uff0c\u4ee5\u53ca\u80bf\u7624\u57fa\u56e0\u7ec4\u5728\u6cbb\u7597\u538b\u529b\u4e0b\u7684\u5feb\u901f\u8fdb\u5316\u800c\u5bfc\u81f4\u7684\u7ec4\u7ec7\u6d3b\u68c0\u7684\u975e\u5b9e\u65f6\u6027\u7b49\u7b49\u3002\u6db2\u4f53\u6d3b\u68c0\u5728\u4e0d\u540c\u7a0b\u5ea6\u4e0a\u53ef\u4ee5\u907f\u514d\u8fd9\u4e9b\u9650\u5236\uff0c\u4f46\u662f\u5728\u6280\u672f\u548c\u8ba1\u7b97\u5206\u6790\u4e0a\u7684\u8981\u6c42\u8981\u8fdc\u8fdc\u9ad8\u4e8e\u7ec4\u7ec7\u6d3b\u68c0\u3002\u8fd9\u4e3b\u8981\u662f\u56e0\u4e3acfDNA\u5728\u8840\u6db2\u4e2d\u7684\u603b\u91cf\u5f88\u4f4e\uff0c\u800cctDNA\u5728cfDNA\u4e2d\u7684\u6bd4\u4f8b\u66f4\u4f4e\uff0c\u5f88\u591a\u65f6\u5019\u4f4e\u4e8e\u5f53\u524d\u6d4b\u5e8f\u4eea\u53ef\u9760\u6027\u7684\u4e0b\u9650\u3002\u8fd9\u5c31\u9700\u8981\u6211\u4eec\u53d1\u5c55\u53ef\u9760\u7684\u5b9e\u9a8c\u6280\u672f\u548c\u8ba1\u7b97\u65b9\u6cd5\u6765\u589e\u52a0\u6d4b\u5e8f\u7684\u51c6\u786e\u6027\u3002cfDNA\u7684\u4f5c\u7528\u53ef\u4ee5\u5927\u4f53\u5206\u4e3a\u4e24\u4e2a\u65b9\u5411\uff1a\u4e2d\u665a\u671f\u764c\u75c7\u7684\u7528\u836f\u6307\u5bfc\u548c\u75c5\u7a0b\u68c0\u6d4b\uff0c\u4ee5\u53ca\u65e9\u671f\u6216\u8d85\u65e9\u671f\u764c\u75c7\u7684\u7b5b\u9009\u8bca\u65ad\u3002\u524d\u4e00\u4e2a\u65b9\u5411\u505a\u7684\u6bd4\u8f83\u591a\uff0c\u4e3b\u8981\u662f\u7531\u4e8ectDNA\u5728\u4e2d\u665a\u671f\u75c5\u4eba\u4e2d\u7684\u542b\u91cf\u8f83\u65e9\u671f\u75c5\u4eba\u8981\u9ad8\uff0c\u6240\u4ee5\u68c0\u6d4b\u7684\u51c6\u786e\u5ea6\u8981\u9ad8\u3002\u56fd\u5185\u6709\u4e0d\u5c11\u516c\u53f8\u90fd\u63a8\u51fa\u4e86\u5404\u81ea\u7684\u4ea7\u54c1\uff0c\u800c\u8c61\u51ef\u6770\uff0c\u7f57\u6c0f\u7b49\u516c\u53f8\u4e5f\u63a8\u51fa\u4e86\u5546\u4e1a\u5316\u7684\u4ea7\u54c1\uff0c\u56e0\u800c\u8fd9\u4e2a\u65b9\u5411\u7ade\u4e89\u6bd4\u8f83\u6fc0\u70c8\u3002\u76f8\u6bd4\u4e4b\u4e0b\uff0c\u7528\u6db2\u4f53\u6d3b\u68c0\u505a\u764c\u75c7\u7684\u65e9\u671f\u7b5b\u9009\u8981\u56f0\u96be\u7684\u591a\uff0c\u4e00\u65b9\u9762\u662f\u7531\u4e8e\u65e9\u671f\u764c\u75c7\u4e2dctDNA\u542b\u91cf\u6781\u4f4e\uff0c\u540c\u65f6\u4e5f\u56e0\u4e3a\u6211\u4eec\u6574\u4e2a\u7814\u7a76\u9886\u57df\u5bf9\u4e8e\u65e9\u671f\u764c\u75c7\u57fa\u56e0\u7ec4\u7684\u8ba4\u8bc6\u8fdc\u8fdc\u4e0d\u53ca\u665a\u671f\u764c\u75c7\u3002\u6700\u8fd1\uff0c\u5728\u7f8e\u56fd\u548c\u4e2d\u56fd\u90fd\u6709\u4e13\u6ce8\u4e8e\u764c\u75c7\u65e9\u7b5b\u7684\u521d\u521b\u516c\u53f8\u7684\u6210\u7acb\uff0c\u6700\u6709\u540d\u7684\u5c31\u662f\u4eceIllumina\u8131\u79bb\u51fa\u6765\u7684Grail\u516c\u53f8\uff0c\u6700\u8fd1\u878d\u8d44\u4e869\u4ebf\u7f8e\u5143\u3002\u4ed6\u4eec\u7684\u76ee\u6807\u662f\u901a\u8fc7\u548c\u7f8e\u56fd\u5404\u5927\u764c\u75c7\u4e2d\u5fc3\u5408\u4f5c\u6765\u8fdb\u884c\u5927\u89c4\u6a21\u7684\u4e34\u5e8a\u8bd5\u9a8c\uff0c\u901a\u8fc7\u8d85\u9ad8\u901a\u91cf\u6d4b\u5e8f\u6765\u5f00\u53d1\u5728\u65e0\u75c7\u72b6\u4eba\u7fa4\u4e2d\u7684\u6cdb\u764c\u75c7(pan-cancer)\u7684\u65e9\u7b5b\u6280\u672f\u3002Grail\u8fd8\u672a\u62ab\u9732\u5177\u4f53\u53d1\u5c55\u8ba1\u5212\uff0c\u6240\u4ee5\u6211\u65e0\u6cd5\u8fdb\u884c\u66f4\u5177\u4f53\u7684\u8bc4\u8bba\u3002\u4f46\u662f\u76f8\u5bf9\u4e8e\u4ed6\u4eec\u7684\u8ba1\u5212\uff0c\u6211\u66f4\u503e\u5411\u4e8e\u9996\u5148\u5728\u7279\u5b9a\u9ad8\u5371\u4eba\u7fa4\u4e2d\u53d1\u5c55\u9488\u5bf9\u7279\u5b9a\u764c\u75c7\u7684\u65e9\u7b5b\u6280\u672f\u3002\u6bd4\u5982\u5728\u4e59\u809d\u6216\u8005\u4e19\u809d\u75c5\u4eba\u4e2d\u7b5b\u67e5\u809d\u764c\uff0c\u5728\u6709\u5bb6\u65cf\u53f2\u6216\u5927\u80a0\u606f\u8089\u53f2\u7684\u75c5\u4eba\u4e2d\u7b5b\u67e5\u80a0\u764c\uff0c\u4ee5\u53ca\u5728\u5438\u70df\u4eba\u7fa4\u4e2d\u7b5b\u67e5\u80ba\u764c\u7b49\u7b49\u3002\u901a\u8fc7\u53d1\u5c55\u8fd9\u4e9b\u6280\u672f\u53d6\u5f97\u7684\u6570\u636e\u548c\u7ecf\u9a8c\uff0c\u53ef\u4ee5\u5e2e\u52a9\u6211\u4eec\u6700\u7ec8\u63a8\u5e7f\u5230\u65e0\u75c7\u72b6\u4eba\u7fa4\u4e2d\u7684\u7b5b\u67e5\u3002\u5728\u8fd9\u4e2a\u8fc7\u7a0b\u4e2d\uff0c\u91cd\u8981\u7684\u4e00\u70b9\u662f\uff0c\u65e0\u8bba\u6280\u672f\u591a\u4e48\u7cbe\u6df1\uff0c\u5728\u7528\u4e8e\u4e34\u5e8a\u524d\uff0c\u4e00\u5b9a\u8981\u7ecf\u8fc7\u5927\u89c4\u6a21\u7684\u4eba\u7fa4\u961f\u5217\u9a8c\u8bc1\uff0c\u5c24\u5176\u662f\u65e9\u671f\u764c\u75c7\u751a\u81f3\u4e34\u5e8a\u8bca\u65ad\u524d\u7684\u6837\u672c\u7684\u9a8c\u8bc1\u3002\u5f88\u591a\u80bf\u7624\u5728\u5176\u65e9\u671f\u548c\u665a\u671f\u4f1a\u6709\u975e\u5e38\u4e0d\u540c\u7684\u57fa\u56e0\u7ec4\u7279\u5f81\uff0c\u6240\u4ee5\u57fa\u4e8e\u665a\u671f\u80bf\u7624\u5f00\u53d1\u7684\u624b\u6bb5\u5728\u65e9\u671f\u7b5b\u67e5\u5e76\u4e0d\u4e00\u5b9a\u6709\u6548\u3002\u603b\u8d77\u6765\u8bb2\uff0c\u867d\u7136\u6db2\u4f53\u6d3b\u68c0\u5728\u80bf\u7624\u65e9\u7b5b\u8fd9\u4e2a\u65b9\u5411\u4ecd\u6709\u76f8\u5f53\u5927\u7684\u6280\u672f\u548c\u9a8c\u8bc1\u65b9\u9762\u7684\u96be\u70b9\u9700\u8981\u514b\u670d\uff0c\u4f46\u662f\u6211\u575a\u4fe1\u5728\u672a\u6765\u7684\u51e0\u5e74\u5185\u8fd9\u4e2a\u65b9\u5411\u7684\u53d1\u5c55\u4f1a\u6709\u7a81\u98de\u731b\u8fdb\u7684\u8fdb\u6b65\uff0c\u6709\u7740\u5de8\u5927\u7684\u7814\u7a76\uff0c\u4e34\u5e8a\uff0c\u4ee5\u53ca\u5546\u4e1a\u4e0a\u7684\u524d\u666f\u3002<\/div>\n
\u00a0<\/div>\n
\u4e09\u3001miRNA\u4f5c\u4e3a\u809d\u7ec6\u80de\u764c\u751f\u7269\u6807\u8bb0<\/div>\n
\u57fa\u56e0\u6167\uff1a\u53bb\u5e746\u6708\uff0c\u60a8\u548cChun Wang\u535a\u58eb\u4e00\u8d77\u53d1\u8868\u4e86\u5173\u4e8e\u5faa\u73afmiRNA\u4f5c\u4e3a\u4e59\u578b\u809d\u708e\u4e2d\u809d\u7ec6\u80de\u764c\u9884\u6d4b\u7684\u751f\u7269\u6807\u8bb0[2]\uff0c\u8bf7\u60a8\u8c08\u8c08\u8fd9\u4e00\u7814\u7a76\u7684\u8fdb\u5c55\u548c\u610f\u4e49\uff0c\u7279\u522b\u7684\uff0c\u5982\u679c\u5e94\u7528\u4e34\u5e8a\u8bca\u65ad\u6807\u8bb0\uff0c\u76f8\u5bf9\u4e8eDNA\uff0cmiRNA\u7684\u7a33\u5b9a\u6027\u8f83\u5dee\uff0c\u5c0f\u7247\u6bb5\u8f83\u5c0f\uff0c\u8fd9\u4f1a\u6709\u4ec0\u4e48\u5f71\u54cd\u5462\uff1f<\/div>\n
\u6768\u6559\u6388\uff1a\u6211\u7684\u5b9e\u9a8c\u5ba4\u5f88\u65e9\u5c31\u5f00\u59cb\u4e86miRNA\u76f8\u5173\u7684\u7814\u7a76\u3002\u5728\u6211\u4eec\u7684\u7814\u7a76\u4e4b\u524d\uff0c\u5df2\u7ecf\u6709\u5c11\u6570\u6587\u732e\u62a5\u5bfc\u5bfb\u627e\u5faa\u73afmiRNA\u6765\u4f5c\u4e3a\u4e59\u809d\u4eba\u7fa4\u4e2d\u809d\u764c\u7684\u6807\u5fd7\u7269\u3002\u4f46\u662f\u4e0d\u5c11\u7814\u7a76\u5305\u62ec\u4e86\u4e0d\u5c11\u665a\u671f\u75c5\u4eba\u7684\u6837\u672c\u3002\u5982\u6211\u524d\u9762\u6240\u8bb2\uff0c\u5f88\u591a\u5728\u665a\u671f\u80bf\u7624\u4e2d\u660e\u663e\u7684\u6807\u5fd7\u7269\u5728\u65e9\u671f\u80bf\u7624\u4e2d\u5e76\u4e0d\u660e\u663e\u3002\u66f4\u91cd\u8981\u7684\u662f\u5927\u591a\u6570\u7814\u7a76\u4f7f\u7528\u7684\u662f\u764c\u75c7\u8bca\u65ad\u540e\u83b7\u53d6\u7684\u8840\u6db2\u6837\u672c\uff0c\u8fd9\u6837\u7684\u7814\u7a76\u7ed3\u679c\u4f1a\u53d7\u5230\u6d41\u884c\u75c5\u5b66\u4e2d\u6240\u8c13\u7684\u53cd\u5411\u56e0\u679c\u5173\u8054(reverse causation)\u7684\u9650\u5236\uff0c\u7b80\u5355\u6765\u8bf4\u5c31\u662f\uff0c\u6211\u4eec\u5e76\u4e0d\u6e05\u695a\u764c\u75c7\u8bca\u65ad\u540e\u6837\u672c\u91cc\u9762\u6807\u5fd7\u7269\u7684\u53d8\u5316\u5230\u5e95\u662f\u764c\u75c7\u7684\u6210\u56e0\u8fd8\u662f\u764c\u75c7\u7684\u540e\u679c\u3002\u9488\u5bf9\u8fd9\u4e9b\u95ee\u9898\uff0c\u6211\u4eec\u505a\u4e86\u4e00\u4e2a\u63a2\u7d22\u6027\u7684\u524d\u77bb\u6027\u7814\u7a76\uff0c\u96c6\u4e2d\u5206\u6790\u4e86\u4ee5\u524d\u6587\u732e\u62a5\u9053\u4e2d\u7684miRNA\u5728\u6211\u4eec\u6536\u96c6\u7684\u90e8\u5206\u524d\u77bb\u6027\u8840\u6db2\u6837\u672c\u91cc\u9762\u7684\u8868\u8fbe\uff0c\u7136\u540e\u5206\u6790\u4e86\u6bcf\u4e2amiRNA\u548c\u809d\u764c\u53d1\u751f\u7684\u5173\u8054\u3002\u6211\u4eec\u53d1\u73b0\u53ea\u6709\u4e00\u90e8\u5206miRNA\u4e0e\u809d\u764c\u53d1\u751f\u6709\u5173\u8054\uff0c\u800c\u5173\u8054\u7684\u5f3a\u5ea6\u4e5f\u5927\u591a\u5f31\u4e8e\u6587\u732e\u91cc\u7684\u62a5\u5bfc\u3002\u6211\u4eec\u57fa\u4e8e\u8fd9\u4e9bmiRNA\u5efa\u7acb\u7684\u7edf\u8ba1\u6a21\u578b\u7684\u9884\u6d4b\u80fd\u529b\u867d\u7136\u6bd4\u4e34\u5e8a\u5e38\u7528\u7684\u7532\u80ce\u86cb\u767d\u4e3a\u9ad8\uff0c\u4f46\u5e76\u4e0d\u80fd\u8fbe\u5230\u4e00\u4e2a\u4ee4\u4eba\u6ee1\u610f\u7684\u5730\u6b65\u3002\u8fd9\u4e2a\u7814\u7a76\u8fdb\u4e00\u6b65\u9a8c\u8bc1\u4e86\u4f7f\u7528\u65e9\u671f\u80bf\u7624\u6837\u672c\u751a\u81f3\u662f\u4e34\u5e8a\u8bca\u65ad\u524d\u6837\u672c\u5bf9\u4e8e\u5f00\u53d1\u764c\u75c7\u65e9\u7b5b\u6280\u672f\u7684\u91cd\u8981\u6027\u3002\u540c\u65f6\u4e5f\u542f\u793a\u6211\u4eec\u5982\u679c\u8981\u53d1\u5c55\u8d85\u9ad8\u51c6\u786e\u5ea6\u7684\u65e9\u8bca\u6280\u672f\uff0c\u6211\u4eec\u5f88\u53ef\u80fd\u9700\u8981\u4f7f\u7528\u6765\u81ea\u4e0d\u540c\u65b9\u9762\u7684\u6570\u636e\uff0c\u4f8b\u5982\u591a\u7ef4\u7ec4\u5b66\uff0c\u6765\u8fdb\u884c\u6574\u5408\u5206\u6790\uff08integrative analysis\uff09\uff0c\u56e0\u4e3a\u6bcf\u4e00\u4e2a\u7ef4\u5ea6\u7684\u6570\u636e\u53ef\u80fd\u4f1a\u5e26\u7ed9\u6211\u4eec\u72ec\u7acb\u7684\uff0c\u4e92\u8865\u7684\u4fe1\u53f7\u3002\u591a\u7ef4\u6570\u636e\u7684\u6574\u5408\u5206\u6790\u6709\u53ef\u80fd\u4f1a\u5bf9\u65e9\u7b5b\u6280\u672f\u4ea7\u751f\u53e0\u52a0\u548c\u534f\u540c\u7684\u6548\u7528\u800c\u589e\u52a0\u6280\u672f\u7684\u7075\u654f\u6027\u548c\u7279\u5f02\u6027\u3002\u6211\u4eec\u9884\u6d4bmiRNA\u5f88\u53ef\u80fd\u4f1a\u4e3a\u8fd9\u79cd\u6574\u5408\u5206\u6790\u63d0\u4f9b\u91cd\u8981\u7684\u4fe1\u606f\u3002miRNA\u786e\u5b9e\u6ca1\u6709DNA\u7a33\u5b9a\uff0c\u4f46\u662f\u7531\u4e8emiRNA\u7247\u6bb5\u5c0f\uff0c\u5176\u6bd4mRNA\u8981\u7a33\u5b9a\u7684\u591a\u3002\u6211\u4eec\u7684\u7ecf\u9a8c\u662f\uff0c\u6b63\u786e\u63d0\u53d6\u548c\u4fdd\u5b58\u7684miRNA\u53ef\u4ee5\u76f8\u5bf9\u7a33\u5b9a\u4fdd\u5b58\u8f83\u957f\u65f6\u95f4\uff0c\u6709\u76f8\u5f53\u7684\u7814\u7a76\u4ef7\u503c\u3002\u4f46\u662f\uff0c\u5728\u5b9e\u9a8c\u8bbe\u8ba1\u4e0a\uff0c\u9700\u8981\u6709\u6240\u6ce8\u610f\u6765\u63a7\u5236\u6279\u6b21\u6548\u5e94(batch effect)\u548c\u4fdd\u5b58\u65f6\u95f4\u7b49\u6df7\u6dc6\u56e0\u7d20(confounding factor)\u5bf9\u7ed3\u679c\u4ea7\u751f\u7684\u5f71\u54cd\u3002<\/div>\n\n
\n![\"eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9HD4lTbAfOUxUWoJBm4TCrPxBHicuzWLcbPl9AyJBThlWfFEuZQdyqOA\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9HD4lTbAfOUxUWoJBm4TCrPxBHicuzWLcbPl9AyJBThlWfFEuZQdyqOA.png\")
<\/figure><\/div>\n\n<\/div>\n
<\/figure><\/div>\n\n<\/div>\nHCC: hepatocellular carcinoma; AFP: alpha-fetoprotein; CI: confidence interval; C-index: concordance index. <\/div>\n
\u56fe\uff1amiRNA\u4f5c\u4e3a\u751f\u7269\u6807\u8bb0\u9884\u6d4bHCC\u4e94\u5e74\u53d8\u5316\u60c5\u51b5\u6e90\uff1ahttp:\/\/www.impactjournals.com<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
\u56db\u3001\u673a\u5668\u5b66\u4e60\u548c\u7cbe\u51c6\u533b\u7597<\/div>\n
<\/div>\n
<\/div>\n
\u57fa\u56e0\u6167\uff1a\u60a8\u8c08\u5230\uff1a\u201c\u5927\u6837\u672c\u91cf\u6570\u636e\u7684\u957f\u671f\u56de\u987e\uff0c\u673a\u5668\u6df1\u5ea6\u5b66\u4e60\u5c06\u6539\u53d8\u4f20\u7edf\u57fa\u56e0\u6570\u636e\u5206\u6790\u7684\u5957\u8def\u201d\u3002\u6df1\u5ea6\u5b66\u4e60\u4f5c\u4e3a\u673a\u5668\u5b66\u4e60\u4e2d\u7684\u524d\u6cbf\u7b97\u6cd5\uff0c\u5e94\u7528\u5230\u57fa\u56e0\u6570\u636e\u5206\u6790\u65f6\uff0c\u53d6\u5f97\u4e86\u5f88\u591a\u8fdb\u5c55\uff0c\u4e5f\u6709\u4e0d\u5c11\u4e34\u5e8a\u533b\u751f\u5bf9\u6b64\u4e0d\u4e86\u89e3\uff0c\u53ef\u5426\u8bf7\u60a8\u4e3e\u51fa1-2\u4e2a\u5b9e\u4f8b\u4ecb\u7ecd\u4e0b\uff1f\u540c\u65f6\uff0c\u673a\u5668\u5b66\u4e60\u6240\u9700\u8981\u5df2\u77e5\u6570\u636e\u7684\u8bad\u7ec3\u96c6\uff0c\u60a8\u8ba4\u4e3a\u5982\u4f55\u6536\u96c6\u548c\u6784\u5efa\u624d\u80fd\u63d0\u9ad8\u6700\u540e\u5efa\u6a21\u7684\u51c6\u786e\u7387\u5462\uff1f<\/div>\n
<\/div>\n
\u6768\u6559\u6388\uff1a\u8fd1\u5e74\u6765\u6211\u548c\u674e\u51b0\u5c71\u6559\u6388\u7684\u5408\u4f5c\u6709\u5f88\u5927\u4e00\u90e8\u5206\u7cbe\u529b\u96c6\u4e2d\u4e8e\u57fa\u4e8e\u5927\u6570\u636e\u7684\u673a\u5668\u5b66\u4e60\u6765\u53d1\u5c55\u764c\u75c7\u65e9\u7b5b\u7684\u6a21\u578b\u3002\u674e\u6559\u6388\u5728\u8fd9\u4e2a\u8fc7\u7a0b\u4e2d\u8d77\u7740\u91cd\u8981\u7684\u4e3b\u5bfc\u4f5c\u7528\u3002\u8fd1\u4e9b\u5e74\u673a\u5668\u5b66\u4e60\u6709\u98de\u901f\u7684\u53d1\u5c55\uff0c\u7279\u522b\u662f\u6df1\u5ea6\u5b66\u4e60\uff0c\u5df2\u7ecf\u5177\u6709\u5728\u4e34\u5e8a\u4e0a\u5e7f\u6cdb\u5e94\u7528\u7684\u53ef\u80fd\u3002\u6bd4\u5982\u6df1\u5ea6\u5b66\u4e60\u7528\u5728\u6d77\u91cf\u7684\u76ae\u80a4\u764c\u7684\u5f71\u50cf\u6570\u636e\u8bad\u7ec3\u51fa\u6765\u7684\u6a21\u578b\u53ef\u4ee5\u5177\u6709\u548c\u4e34\u5e8a\u4e13\u5bb6\u4e00\u6837\u7684\u8bca\u65ad\u53ca\u5206\u578b\u7684\u51c6\u786e\u5ea6\uff0c\u8fd9\u662f\u5f88\u4e86\u4e0d\u8d77\u7684\u3002\u7c7b\u4f3c\u7684\u6280\u672f\u5f88\u5feb\u4f1a\u7528\u5728\u4e34\u5e8a\u4e0a\u6765\u8f85\u52a9\u8bca\u65ad\uff0c\u5c06\u5927\u5927\u63d0\u9ad8\u533b\u751f\u7684\u6548\u7387\u548c\u51c6\u786e\u5ea6\u3002\u5bf9\u4e8e\u57fa\u56e0\u7ec4\u6570\u636e\u7684\u5206\u6790\uff0c\u673a\u5668\u5b66\u4e60\uff0c\u7279\u522b\u662f\u6df1\u5ea6\u5b66\u4e60\uff0c\u66f4\u591a\u7684\u8fd8\u5904\u5728\u79d1\u7814\u9636\u6bb5\uff0c\u4e3b\u8981\u662f\u56e0\u4e3a\u57fa\u56e0\u7ec4\u53ca\u5176\u590d\u6742\uff0c\u76ee\u524d\u6211\u4eec\u8fd8\u6ca1\u6709\u5bf9\u57fa\u56e0\u7ec4\u7684\u529f\u80fd\u6709\u6df1\u5165\u7684\u4e86\u89e3\u3002\u968f\u7740\u57fa\u56e0\u7ec4\u5b66\u6570\u636e\u4e0d\u65ad\u7684\u4ea7\u751f\u548c\u79ef\u7d2f\uff0c\u6df1\u5ea6\u5b66\u4e60\u4e5f\u5df2\u7ecf\u5f00\u59cb\u663e\u793a\u51fa\u5b83\u72ec\u5230\u7684\u5904\u7406\u6d77\u91cf\u57fa\u56e0\u7ec4\u6570\u636e\u7684\u8d85\u5f3a\u4e4b\u5904\u3002\u4e3b\u8981\u7684\u5e94\u7528\u4e4b\u4e00\u662f\u6765\u6ce8\u91ca\u6211\u4eec\u4eba\u7c7b\u57fa\u56e0\u7ec4\u768430\u4ebf\u4e2a\u78b1\u57fa\u5bf9\u529f\u80fd\u7684\u5f71\u54cd\uff0c\u6765\u8f85\u52a9\u4e2a\u4eba\u5168\u57fa\u56e0\u7ec4\u7684\u89e3\u8bfb\uff0c\u5305\u62ec\u5bf9\u75be\u75c5\u7684\u9884\u6d4b\uff0c\u8bca\u65ad\u548c\u5e72\u9884\u3002\u4e00\u4e2a\u5f88\u597d\u7684\u4f8b\u5b50\u5c31\u662fDeep Genomics\u516c\u53f8\u901a\u8fc7\u6df1\u5ea6\u5b66\u4e60\u6765\u9884\u6d4b\u9057\u4f20\u53d8\u5f02\u5bf9RNA\u526a\u5207\u7684\u5f71\u54cd\u4ee5\u53ca\u4e0e\u76f8\u5173\u75be\u75c5\u7684\u5173\u7cfb\u3002\u73b0\u5728\u8fd9\u4e9b\u5e94\u7528\u66f4\u591a\u7684\u662f\u4ece\u57fa\u56e0\u7ec4\u529f\u80fd\u7684\u89d2\u5ea6\u51fa\u53d1\uff0c\u800c\u771f\u6b63\u7684\u8981\u8fbe\u5230\u6df1\u5ea6\u5b66\u4e60\u5728\u4e34\u5e8a\u4e0a\u7684\u5e94\u7528\u6211\u4eec\u9700\u8981\u7684\u662f\u57fa\u56e0\u7ec4\u548c\u4e34\u5e8a\u7d27\u5bc6\u7ed3\u5408\u7684\u5927\u6570\u636e\u3002\u5728\u6536\u96c6\u548c\u6784\u5efa\u8fd9\u4e9b\u6570\u636e\u7684\u7b56\u7565\u4e0a\uff0c\u6211\u8ba4\u4e3a\u6211\u4eec\u5e94\u8be5\u6ce8\u91cd\u4ee5\u4e0b\u51e0\u70b9\u3002\u7b2c\u4e00\u662f\u6570\u636e\u7684\u76f8\u5173\u6027\u3002\u5982\u6211\u4e4b\u524d\u5f3a\u8c03\uff0c\u5982\u679c\u505a\u80bf\u7624\u65e9\u7b5b\uff0c\u90a3\u4e48\u65e9\u671f\u80bf\u7624\u6216\u4e34\u5e8a\u8bca\u65ad\u524d\u7684\u6570\u636e\u8981\u6709\u6548\u4e8e\u4e2d\u665a\u671f\u80bf\u7624\u7684\u6570\u636e\uff0c\u800c\u65e9\u671f\u7684\u7eb5\u5411\u6027\u7684\u6837\u672c\u6570\u636e\u66f4\u662f\u5173\u952e\u3002\u7b2c\u4e8c\u662f\u6570\u636e\u7684\u89c4\u8303\u6027\u3002\u57fa\u56e0\u7ec4\u673a\u5668\u5b66\u4e60\u7684\u7ed3\u679c\u5f97\u76ca\u4e8e\u5927\u6570\u636e\u7684\u6570\u91cf\uff0c\u800c\u5f88\u591a\u65f6\u5019\u57fa\u56e0\u7ec4\u7684\u5927\u6570\u636e\u9700\u8981\u4ece\u5f88\u591a\u4e0d\u540c\u6765\u6e90\u5f97\u5230\u3002\u90a3\u4e48\u5982\u4f55\u89c4\u8303\uff0c\u534f\u8c03\uff0c\u548c\u6574\u5408\u8fd9\u4e9b\u6709\u7740\u4e0d\u540c\u6765\u6e90\u548c\u4e0d\u540c\u7814\u7a76\u76ee\u5730\u7684\u6570\u636e\u6765\u63a7\u5236\u5176\u4e2d\u53ef\u80fd\u4ea7\u751f\u7684\u5e72\u6270\u56e0\u7d20\u5bf9\u4e8e\u6700\u7ec8\u7684\u5206\u6790\u7ed3\u679c\u6709\u76f4\u63a5\u5f71\u54cd\u3002\u7b2c\u4e09\u662f\u6570\u636e\u7684\u7ef4\u5ea6\u3002\u5bf9\u4e8e\u764c\u75c7\u8fd9\u6837\u4e00\u4e2a\u6210\u56e0\u6781\u5176\u590d\u6742\u7684\u591a\u56e0\u7d20\u75be\u75c5\uff0c\u5355\u4e00\u7ec4\u5b66\u7684\u6570\u636e\u4e0d\u5bb9\u6613\u8fbe\u5230\u6781\u9ad8\u7684\u9884\u6d4b\u6027\u80fd\u3002\u800c\u5c06\u591a\u7ef4\u5ea6\u7684\u6570\u636e\u6574\u5408\u5230\u4e00\u8d77\u53ef\u80fd\u4f1a\u5bf9\u53d1\u5c55\u4e34\u5e8a\u6709\u6548\u7684\u65e9\u7b5b\u6280\u672f\u8d77\u5230\u91cd\u8981\u7684\u5f71\u54cd\u3002\u6211\u4eec\u5728\u81ea\u5df1\u7684\u673a\u5668\u5b66\u4e60\u6280\u672f\u53d1\u5c55\u8fc7\u7a0b\u4e2d\uff0c\u540c\u65f6\u5229\u7528\u4e86\u516c\u5171\u6570\u636e\u5e93\u548c\u6211\u4eec\u81ea\u5df1\u4ea7\u751f\u7684\u5f88\u591a\u9488\u5bf9\u65e9\u7b5b\u7814\u7a76\u7684\u7279\u5b9a\u7684cfDNA\u76f8\u5173\u7684\u6d4b\u5e8f\u6570\u636e\u3002\u4e24\u8005\u7684\u7ed3\u5408\u4f7f\u6211\u4eec\u65e2\u5145\u5206\u5229\u7528\u5230\u4e86\u6d77\u91cf\u7684\u516c\u5171\u7814\u7a76\u6210\u679c\uff0c\u53c8\u5f97\u76ca\u4e8e\u6211\u4eec\u7279\u6709\u7684\u6837\u672c\u548c\u6570\u636e\uff0c\u5bf9\u6211\u4eec\u63d0\u9ad8\u9884\u6d4b\u6a21\u578b\u7684\u51c6\u786e\u7387\u8d77\u5230\u4e86\u91cd\u8981\u7684\u4f5c\u7528\u3002\u5f53\u7136\u5728\u8fd9\u4e2a\u8fc7\u7a0b\u4e2d\u9700\u8981\u8003\u8651\u8ba1\u7b97\u7684\u590d\u6742\u6027\u548c\u6280\u672f\u7684\u6210\u672c\u3002\u5728\u9996\u5148\u4fdd\u8bc1\u51c6\u786e\u7387\u7684\u524d\u63d0\u4e0b\uff0c\u968f\u7740\u6d4b\u5e8f\u6280\u672f\u548c\u5206\u6790\u624b\u6bb5\u7684\u8fdb\u4e00\u6b65\u53d1\u5c55\uff0c\u8fd9\u4e9b\u5c40\u9650\u90fd\u4f1a\u9010\u6e10\u88ab\u514b\u670d\u3002<\/div>\n
<\/div>\n
<\/div>\n
\n\n
\n![\"eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9wguKNs8Wga4ia8EwGZ2D9ecibtEHwOm2noiaDQhjelHEbc4hmCWbR06aQ\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9wguKNs8Wga4ia8EwGZ2D9ecibtEHwOm2noiaDQhjelHEbc4hmCWbR06aQ.jpeg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n\u56fe\u6765\u81ea\uff1ahttp:\/\/truthisscary.com\/<\/div>\n
\u4e94\u3001\u300aNGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u4f1a\u300b\u6f14\u8bb2\u9884\u544a<\/div>\n
\u57fa\u56e0\u6167\uff1a\u6b23\u95fb\u60a8\u57283\u670831\u65e5\u5c06\u6765\u676d\u5dde\u300aNGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u4f1a\u300b\u4e0a\u505a\u4e00\u573a\u7cbe\u5f69\u7684\u5b66\u672f\u62a5\u544a\uff0c\u53ef\u5426\u7ed9\u57fa\u56e0\u6167\u8bfb\u8005\u7565\u5fae\u900f\u6f0f\u4e0b\u5728\u5927\u4f1a\u4e0a\u60a8\u6f14\u8bb2\u5185\u5bb9\u7684\u6982\u8981\u5462\uff1f<\/div>\n
\u6768\u6559\u6388\uff1a\u6f14\u8bb2\u7684\u4e3b\u8981\u5185\u5bb9\u662f\u6211\u4eec\u4f7f\u7528\u5168\u57fa\u56e0\u7ec4cfDNA\u7684\u4f4e\u9891\u6d4b\u5e8f\u505a\u7684\u809d\u764c\u65e9\u7b5b\u65b9\u9762\u7684\u6570\u636e\u5206\u6790\u3002\u6211\u975e\u5e38\u671f\u671b\u5728\u5927\u4f1a\u4e0a\u548c\u540c\u884c\u4eec\u4e00\u8d77\u63a2\u8ba8\u548c\u5408\u4f5c\u53d1\u5c55\u764c\u75c7\u65e9\u7b5b\u7684\u6280\u672f\uff0c\u4e3a\u5e2e\u52a9\u63a7\u5236\u4e2d\u7f8e\u4e24\u56fd\u7684\u764c\u75c7\u53d1\u75c5\u548c\u6b7b\u4ea1\u7387\u505a\u51fa\u6211\u4eec\u7684\u8d21\u732e\u3002<\/div>\n
\u00a0<\/div>\n
\u53c2\u8003\u8d44\u6599\uff1a<\/div>\n
1.Cristofanilli, M., Budd, et.al\u201cCirculating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer\u201d N Engl J Med (2004): 351:781-791. DOI: 10.1056\/NEJMoa040766.<\/div>\n
2. http:\/\/www.impactjournals.com\/oncotarget\/index.php?journal=oncotarget&page=article&op=view&path%5B%5D=9429&path%5B%5D=29220<\/div>\n
3.http:\/\/www.jefferson.edu\/university\/jmc\/departments\/medical_oncology\/faculty\/yang.html\/publications<\/div>\n\n
\n![\"eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9UhTna42RXpq6FwmGGTF4icLicQ03atjZz1lvvMBsmPmibRSq7icT4DTl4A\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9UhTna42RXpq6FwmGGTF4icLicQ03atjZz1lvvMBsmPmibRSq7icT4DTl4A.png\")
<\/figure><\/div>\n\n<\/div>\n
<\/figure><\/div>\n\n<\/div>\n\n\n
\n![\"eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9IIxibyKp3IwZ4t5xHG6AHsTf78c76RVLdWicwM1FElyNVaow5qPGEG1g\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/eicZhoGYCfyaVoIqGNMLcS7o6sIXaHZe9IIxibyKp3IwZ4t5xHG6AHsTf78c76RVLdWicwM1FElyNVaow5qPGEG1g.png\")
<\/figure><\/div>\n\n<\/div>\n
<\/figure><\/div>\n\n<\/div>\n<\/div>\n
<\/div>\n
<\/div>\n
\u300a\u7b2c\u56db\u5c4aNGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u4f1a\u300b\u7cbe\u5f69\u9884\u544a<\/div>\n
<\/div>\n
<\/div>\n
\u65f6\u95f4<\/div>\n
\u5185\u5bb9<\/div>\n
\u5609\u5bbe<\/div>\n
\u4e0a\u5348 \u4e28 NGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u4f1a<\/div>\n
08:00-09:00<\/div>\n
\u5927\u4f1a\u7b7e\u5230<\/div>\n
09:00-09:10<\/div>\n
\u4e3b\u6301\u4eba\u5f00\u573a<\/div>\n
09:10-09:15<\/div>\n
\u4e3b\u529e\u65b9\u81f4\u8f9e<\/div>\n
\u4e3b\u529e\u65b9<\/div>\n
09:15-09:20<\/div>\n
\u9886\u5bfc\u81f4\u8f9e<\/div>\n
\u653f\u5e9c\u9886\u5bfc<\/div>\n
09:20-09:45<\/div>\n
Single Molecule Electronic DNA Sequencing by Synthesis Using Tagged Nucleotides and Nanopore Detection<\/div>\n
\u97a0\u666f\u6708 \u6559\u6388<\/div>\n
Center for Genome Technology and Biomolecular Engineering, Departments of Chemical Engineering and Pharmacology, Columbia University<\/div>\n
09:45-10:10<\/div>\n
\u7a33\u5b9a\u9ad8\u6548\u7684\u65b0\u578b\u7eb3\u7c73\u5b54\u6d4b\u5e8f\u5206\u5b50MspA<\/div>\n
\u5218\u5168\u4fca \u6559\u6388<\/div>\n
\u4e1c\u5357\u5927\u5b66<\/div>\n
10:10-10:35<\/div>\n
\u57fa\u4e8e\u9ad8\u901a\u91cf\u6d4b\u5e8f\u7684\u7cfb\u7edf\u89e3\u51b3\u65b9\u6848<\/div>\n
\u5218\u5065<\/div>\n
\u534e\u5927\u667a\u9020\u4eea\u5668\u5f00\u53d1\u603b\u76d1<\/div>\n
10:35-11:00<\/div>\n
\u667a\u80fd\u52a0\u6837\u9ad8\u901a\u91cf\u5355\u5206\u5b50\u57fa\u56e0\u7ec4\u7ed3\u6784\u53d8\u5f02\u68c0\u6d4b\u5e73\u53f0Saphyr<\/div>\n
\u66f9\u6db5 \u535a\u58eb<\/div>\n
Bionano\u521b\u59cb\u4eba\u517c\u9996\u5e2d\u79d1\u5b66\u5bb6<\/div>\n
11:00-11:25<\/div>\n
\u4f53\u6db2\u6837\u672c\u4e2d\u9ad8\u901a\u91cf\u7a00\u6709\u5355\u7ec6\u80de\u81ea\u52a8\u5206\u79bb\u4e0e\u5355\u7ec6\u80de\u6d4b\u5e8f\u5e94\u7528<\/div>\n
\u65bd\u5947\u60e0 \u6559\u6388<\/div>\n
\u4e0a\u6d77\u4ea4\u901a\u5927\u5b66<\/div>\n
11:25-11:40<\/div>\n
\u542f\u52a8\u4eea\u5f0f<\/div>\n
11:40-13:00<\/div>\n
\u5348\u9910<\/div>\n
\u4e0b\u5348 \u4e28 NGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u4f1a<\/div>\n
13:00-13:15<\/div>\n
\u4e3b\u6301\u4eba\u5f00\u573a<\/div>\n
13:15-13:40<\/div>\n
Universal Haplotype-Based Noninvasive Prenatal Testing for Single Gene Diseases (\u5355\u57fa\u56e0\u75be\u75c5\u65e0\u521b\u8bca\u65ad\u7684\u901a\u7528\u65b9\u6cd5)<\/div>\n
\u6c5f\u57f9\u52c7 \u6559\u6388<\/div>\n
\u9999\u6e2f\u4e2d\u6587\u5927\u5b66<\/div>\n
13:40-14:05<\/div>\n
\u4e0d\u4f9d\u8d56\u9ad8\u901a\u91cf\u6d4b\u5e8f\u7684\u65e0\u521b\u4ea7\u524dNIPT<\/div>\n
\u5218\u8d85 \u535a\u58eb<\/div>\n
\u5929\u660a\u751f\u7269\u533b\u836f\uff08\u82cf\u5dde\uff09\u6709\u9650\u516c\u53f8\u9996\u5e2d\u79d1\u5b66\u5bb6<\/div>\n
14:05-14:30<\/div>\n
\u5168\u57fa\u56e0\u7ec4cfDNA\u667a\u80fd\u6570\u636e\u5206\u6790\u5728\u764c\u75c7\u65e9\u671f\u7b5b\u9009\u4e2d\u7684\u5e94\u7528<\/div>\n
\u6768\u864e\u5c71 \u535a\u58eb<\/div>\n
\u8d39\u57ceThomas Jefferson\u5927\u5b66Sidney Kimmel\u764c\u75c7\u4e2d\u5fc3<\/div>\n
14:30-14:45<\/div>\n
\u8336\u6b47<\/div>\n
14:45-15:10<\/div>\n
\u57fa\u4e8eDNA\u7532\u57fa\u5316\u7684\u9ad8\u7075\u654f\u5ea6\u80bf\u7624\u6db2\u4f53\u6d3b\u68c0<\/div>\n
\u5218\u854a \u535a\u58eb<\/div>\n
\u4e0a\u6d77\u9e4d\u8fdc\u57fa\u56e0CTO<\/div>\n
15:10-15:35<\/div>\n
\u57fa\u4e8e\u5faa\u73af\u80bf\u7624DNA\u7684\u80bf\u7624\u65e9\u671f\u68c0\u6d4b<\/div>\n
\u5218\u671d\u715c \u535a\u58eb<\/div>\n
\u6df1\u5733\u56e0\u5408\u751f\u7269CEO<\/div>\n
15:35-16:00<\/div>\n
\u5bfb\u627e\u7b2c\u4e8c\u4ee3\u4e2a\u4eba\u57fa\u56e0\u7ec4\u4ea7\u54c1\u6210\u529f\u4e4b\u8def<\/div>\n
\u5f90\u5174 \u535a\u58eb<\/div>\n
Genos\u521b\u4e16\u56e2\u961f\u6210\u5458\u3001\u751f\u7269\u4fe1\u606f\u4ea7\u54c1\u603b\u76d1<\/div>\n
16:00-16:25<\/div>\n
\u533b\u7597\u5065\u5eb7\u521b\u65b0\u4e0e\u843d\u5730—\u57fa\u56e0\u4e0e\u8868\u578b\u7684\u8fde\u63a5<\/div>\n
\u987e\u536b\u7ea2 \u535a\u58eb<\/div>\n
\u4e2d\u65e5\u533b\u9662\u8fd0\u52a8\u969c\u788d\u4e0e\u795e\u7ecf\u9057\u4f20\u75c5\u7814\u7a76\u4e2d\u5fc3\u8d1f\u8d23\u4eba\u3001CHPO\u603b\u534f\u8c03\u4eba<\/div>\n
16:25-16:50<\/div>\n
\u9ec4\u91d1\u5341\u5e74\u2014\u2014\u56fd\u5185\u5916\u57fa\u56e0\u4f01\u4e1a\u5e03\u5c40\u68b3\u7406<\/div>\n
\u6c6a\u4eae<\/div>\n
\u57fa\u56e0\u6167\u521b\u59cb\u4eba\u517cCEO<\/div>\n
16:50-17:35<\/div>\n
\u5706\u684c\u8bba\u575b<\/div>\n
\u5609\u5bbe\u656c\u8bf7\u671f\u5f85<\/div>\n
17:35-18:00<\/div>\n
\u5927\u4f1a\u4e3b\u8bae\u7a0b\u7ed3\u675f\uff0c\u5609\u5bbe\u5408\u5f71<\/div>\n
\u665a\u4e0a | \u541b\u8054-NGS\u521b\u65b0\u5f00\u53d1\u8005\u4e4b\u591c\uff08\u665a\u5bb4\uff09<\/div>\n
18:00-18:10<\/div>\n
\u4e3b\u6301\u4eba\u5f00\u573a<\/div>\n
18:10-18:20<\/div>\n
\u4e3b\u529e\u65b9\u81f4\u8f9e<\/div>\n
\u534f\u4f1a\u4ee3\u8868<\/div>\n
18:20-18:40<\/div>\n
\u665a\u5bb4\u795d\u9152\u8f9e<\/div>\n
\u541b\u8054\u8d44\u672c<\/div>\n
18:40-19:00<\/div>\n
\u4e3b\u9898\u6f14\u8bb2\uff08\u4e13\u4e1a\u9886\u57df\uff09<\/div>\n
\u738b\u5b66\u521a<\/div>\n
\u8d1d\u58f3\u793e\u521b\u59cb\u5408\u4f19\u4eba<\/div>\n
19:00-19:20<\/div>\n
\u4e3b\u9898\u6f14\u8bb2\uff08\u533b\u7597\u673a\u6784\uff09<\/div>\n
\u90d1\u6770<\/div>\n
\u6811\u5170\u533b\u7597\u4ea7\u4e1a\u57fa\u91d1<\/div>\n
19:20-19:25<\/div>\n
\u6696\u573a\u8868\u6f14<\/div>\n
\u534f\u4f1a\u6587\u827a\u4ee3\u8868<\/div>\n
19:25-19:40<\/div>\n
\u9881\u53d1NGS\u521b\u65b0\u5f00\u53d1\u8005\u5927\u5956<\/div>\n
19:40-19:50<\/div>\n
\u4e3b\u9898\u6f14\u8bb2\uff08\u6295\u8d44\u5206\u6790\uff09<\/div>\n
\u666e\u534e\u8d44\u672c<\/div>\n
19:50-20:00<\/div>\n
\u4e3b\u9898\u6f14\u8bb2\uff08\u884c\u4e1a\u5206\u6790\uff09<\/div>\n
\u4e1c\u65b9\u8bc1\u5238<\/div>\n
20:00-20:15<\/div>\n
\u4e3b\u9898\u6f14\u8bb2\uff08\u884c\u4e1a\u62a5\u544a\uff09<\/div>\n
\u5609\u5bbe\u656c\u8bf7\u671f\u5f85<\/div>\n
20:15-20:30<\/div>\n
\u81ea\u7531\u4ea4\u6d41<\/div>\n
\uff08\u6ce8\uff1a\u4ee5\u5f53\u5929\u65e5\u7a0b\u4e3a\u4e3b\uff09<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
Connection is power<\/div>\n
\u57fa\u56e0\u6167 GeneClub<\/div>\n
<\/div>\n
<\/div>\n
\u6bcf\u65e5\u56fd\u5185\u5916\u7cbe\u51c6\u533b\u7597\u8d44\u8baf\uff1a\u300aGeneMail\u300b<\/div>\n
\u6bcf\u5468\u6df1\u5ea6\u91c7\u8bbf\u884c\u4e1a\u5927\u5496\uff1a\u300a\u5927\u5496\u8bba\u5065\u300b<\/div>\n
\u6bcf\u6708\u5f55\u5236\u884c\u4e1a\u4e09\u4eba\u8c08\uff1a\u300a\u57fa\u56e0\u4e09\u4eba\u884c\u300b<\/div>\n
\u6bcf\u5b63\u5ea6\u51fa\u884c\u4e1a\u62a5\u544a\uff1a\u300a\u6167\u773c\u7814\u7a76\u300b<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
<\/div>\n
\n\n
\n![\"eicZhoGYCfyaVpiatR0xZeJdswnqCLAYcsOE9rZpe7konhTSIHJeGefsPDzFqiaCnj6teKeBbpGzSbDc42lSCnia5Q\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/eicZhoGYCfyaVpiatR0xZeJdswnqCLAYcsOE9rZpe7konhTSIHJeGefsPDzFqiaCnj6teKeBbpGzSbDc42lSCnia5Q.png\")
<\/figure><\/div>\n\n<\/div>\n
<\/figure><\/div>\n\n<\/div>\n<\/div>\n
<\/div>\n
<\/div>\n
\u58f0\u660e<\/div>\n
1. \u4ee5\u4e0a\u5185\u5bb9\u662f\u57fa\u56e0\u6167\u72ec\u7acb\u7b56\u5212\u3001\u7f16\u8f91\u6210\u6587\u3002\u7248\u6743\u5c5e\u4e8e\u57fa\u56e0\u6167\uff0c\u5728\u5c0a\u91cd\u7248\u6743\u60c5\u51b5\u4e0b\uff0c\u6b22\u8fce\u8f6c\u53d1\u3002\u8f6c\u8f7d\u8bf7\u6ce8\u660e\uff1a\u6765\u6e90\u4e8e\u57fa\u56e0\u6167\u3002<\/div>\n
<\/div>\n
2.\u57fa\u56e0\u6167\u662f\u4e00\u5bb6\u7b2c\u4e09\u65b9\u72ec\u7acb\u7684\u884c\u4e1a\u4fe1\u606f\u670d\u52a1\u548c\u77e5\u8bc6\u670d\u52a1\u516c\u53f8\uff0c\u6211\u4eec\u79c9\u6301\u5ba2\u89c2\u3001\u4e25\u8c28\u3001\u4e2d\u7acb\u7684\u6001\u5ea6\uff0c\u4ece\u591a\u65b9\u6e20\u9053\u6536\u96c6\u5e76\u53d1\u5e03\u4fe1\u606f\uff0c\u4f9b\u884c\u4e1a\u53c2\u8003\u3002\u4f46\u53d7\u6536\u96c6\u5f53\u65f6\u4fe1\u606f\u516c\u5f00\u7684\u65f6\u6548\u6027\uff0c\u4e0d\u540c\u6e20\u9053\u5b58\u5728\u4e0d\u540c\u89c1\u89e3\uff0c\u4e0d\u80fd\u5b8c\u5168\u4fdd\u8bc1\u4fe1\u606f\u7684\u5b8c\u6574\u6027\u548c\u51c6\u786e\u6027\uff0c\u5982\u6709\u9519\u6f0f\u4e4b\u5904\uff0c\u6b22\u8fce\u6307\u6b63\u3002<\/div>\n
<\/div>\n
<\/div>\n
\u884c\u7814\u3001\u54a8\u8be2\u3001\u4f1a\u8bae\u3001\u54c1\u5ba3\u7b49\u670d\u52a1\uff1a<\/div>\n
\u7535\u8bdd\uff1a010-56527551 \/ 400-088-7466<\/div>\n
\u5730\u5740\uff1a\u5317\u4eac\u5e02\u6d77\u6dc0\u533a\u4e2d\u5173\u6751\u5927\u88571\u53f7<\/div>\n
\u5b98\u7f51\uff1awww.geneclub.net.cn<\/div>\n
\u90ae\u7bb1\uff1ainfo@genonet.cn<\/div>\n
<\/div>\n
<\/div>\n
\u57fa\u56e0\u6167<\/div>\n
\u7cbe\u51c6\u533b\u7597<\/div>\n
\u884c\u4e1a\u8fde\u63a5\u5668<\/div>\n
\u957f\u6309\u5173\u6ce8<\/div>\n\n
\n![\"eicZhoGYCfyZYwdCafib0wr4HxcjzHjllGtQPicsLaPhtHQl6lC53yibmAuLhFKscjSicsAGB8skX2tnsC80micOlwhw\"\/](\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/eicZhoGYCfyZYwdCafib0wr4HxcjzHjllGtQPicsLaPhtHQl6lC53yibmAuLhFKscjSicsAGB8skX2tnsC80micOlwhw.jpg\")
<\/figure><\/div>\n\n
<\/figure><\/div>\n\n<\/div>\n
<\/div>\n
<\/div>","protected":false},"excerpt":{"rendered":"
\u300a\u5927\u5496\u8bba\u5065\u300b\u603b\u7b2c25\u671f\u65bd\u5947\u60e0 \u6559\u6388\u5173\u952e\u8bcd\uff1a\u764c\u75c7\u65e9\u7b5b\u5efa\u6a21 cfDNA\u5927\u6570\u636e\u667a\u80fd\u5206\u6790 miRNA\u751f\u7269\u6807\u8bb0\u5efa\u8bae\u7528<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[10],"tags":[2401,1435],"class_list":["post-11619","post","type-post","status-publish","format-standard","hentry","category-thinktank","tag-2401","tag-1435"],"_links":{"self":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/11619","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/comments?post=11619"}],"version-history":[{"count":2,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/11619\/revisions"}],"predecessor-version":[{"id":14549,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/11619\/revisions\/14549"}],"wp:attachment":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/media?parent=11619"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/categories?post=11619"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/tags?post=11619"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}