{"id":11076,"date":"2017-09-27T23:20:52","date_gmt":"2017-09-27T15:20:52","guid":{"rendered":"http:\/\/mp.weixin.qq.com\/s?__biz=MzI3NjUzOTM1Mg==&#038;mid=100001829&#038;idx=1&#038;sn=b9be2cabf944f4109ec2b630b7ab4707&#038;chksm=6b72ba925c053384d064a46345e18a443e2e4760bb0c7b0182f3955a23722b31aa1de8194cee#rd"},"modified":"2026-04-09T09:42:22","modified_gmt":"2026-04-09T01:42:22","slug":"9997102","status":"publish","type":"post","link":"https:\/\/www.geneclub.net.cn\/index.php\/2017\/09\/27\/9997102\/","title":{"rendered":"\u57fa\u56e0\u6167CSCO\u62a5\u9053 | 9\u670827\u65e5\u5b66\u672f\u5e74\u4f1a\u4e73\u817a\u764c\u3001\u80ba\u764c\u3001\u80bf\u7624\u3001\u5206\u5b50\u6807\u5fd7\u7269\u3001\u7cbe\u51c6\u533b\u5b66"},"content":{"rendered":"<p><!-- wechat_content_hash: caf7e0c707820ad3 --><\/p>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgTs7EvkIvaL9iaxH58RWS4hMSua2bpu0OvzUl1zL3EL0yicv2V9Gny66g.gif\" alt=\"RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgTs7EvkIvaL9iaxH58RWS4hMSua2bpu0OvzUl1zL3EL0yicv2V9Gny66g\"\/><\/figure><\/div>\n\n<\/div>\n<div>\u5173\u952e\u5b57\uff1a\u4e73\u817a\u764c\u5927\u6570\u636e\u3001\u80ba\u764c\u9776\u5411\u6cbb\u7597\u3001\u80bf\u7624\u533b\u5e08<\/div>\n<div>\u5206\u5b50\u6807\u5fd7\u7269\u3001\u4e2a\u4f53\u5316\u8bca\u7597\u3001\u7cbe\u51c6\u533b\u5b66<\/div>\n<div>\u5927\u7ea6\u7528\u65f6\uff1a5\u5206\u949f<\/div>\n<div>\u4e73\u817a\u764c\u5927\u6570\u636e\u4e13\u573a<\/div>\n<div>\uff089\u670827\u65e511\uff1a00-12\uff1a00\uff09<\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfg8nibtHDVUkGJ1h7ABTEjKP2NBJFibCYTQKrK13knz4DggNbE1Y2KBxGg.jpeg\" alt=\"RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfg8nibtHDVUkGJ1h7ABTEjKP2NBJFibCYTQKrK13knz4DggNbE1Y2KBxGg\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div><\/div>\n<div><\/div>\n<div>1\u3001\u4ece\u201c\u771f\u5b9e\u201d\u5230\u201c\u771f\u77e5\u201d<\/div>\n<div>\u771f\u5b9e\u4e16\u754c\u8bc1\u636e(Real World Evidence,RWE)\u662f\u6e90\u4e8e\u5728\u7279\u5b9a\u7814\u7a76\u80cc\u666f\u4e0b\u5bf9\u771f\u5b9e\u4e16\u754c\u6570\u636e.(RealWorld Data,RWD)\u7684\u8fdb\u4e00\u6b65\u6c47\u603b\u5206\u6790\uff0c\u83b7\u5f97\u80fd\u591f\u8bc1\u660e\u533b\u836f\u4ea7\u54c1\u5b89\u5168\u6027\u6216\u6709\u6548\u6027\u7684\u8bc1\u636e\uff0c\u800c\u8fd9\u4e00\u7814\u7a76\u8fc7\u7a0b\u79f0\u4e3a\u771f\u5b9e\u4e16\u754c\u7814\u7a76(Real-World Study, RWS ).<\/div>\n<div>\u4e73\u817a\u764c\u8bca\u7597\u771f\u5b9e\u4e16\u754c\u6570\u636e\u5206\u6790\uff1a\u4ece\u4e34\u5e8a\u8bd5\u9a8c\u5230\u4e34\u5e8a\u5b9e\u8df5\u4e2d\uff0c\u8be5\u7528\u836f\u7684\u672a\u7528\uff0c\u8be5\u505c\u836f\u7684\u672a\u505c\uff1b\u5730\u533a\u5dee\u5f02\u660e\u663e\u3002\u4e14\u53d7\u7ecf\u6d4e\u56e0\u7d20\u3001\u53ef\u53ca\u6027\u3001\u533b\u4fdd\u653f\u7b56\u548c\u533b\u60a3\u4e2a\u4f53\u7684\u5f71\u54cd\u3002<\/div>\n<div>RWS\u4e0eRCT\u5e76\u4e0d\u77db\u76fe\uff0c\u5b9e\u4e3a\u4e92\u8865\uff0c\u4eceRWS\u7684\u201c\u771f\u5b9e\u201d\u6570\u636e\u51fa\u53d1\uff0c\u4ee5RCT\u7b49\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\u4e3a\u57fa\u7840\uff0c\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u51fa\u201c\u771f\u77e5\u201d\u3002<\/div>\n<div>\u5927\u6570\u636e\u5e73\u53f0\u662f\u4e00\u628a\u53cc\u5203\u5251\uff0c\u6570\u636e\u7684\u5b89\u5168\u6027\u548c\u76d1\u7ba1\u6709\u5f85\u52a0\u5f3a\uff0c\u9690\u79c1\u4fe1\u606f\u7684\u4e0d\u5f53\u5229\u7528\u4e5f\u4e0d\u5bb9\u5ffd\u89c6\u3002\u771f\u5b9e\u3001\u771f\u77e5\u3001\u771f\u7406\u8f6c\u5316\u9700\u8981\u591a\u65b9\u4f4d\u7684\u63a8\u8fdb\u3002<\/div>\n<div>RCT\u662f\u5faa\u8bc1\u533b\u5b66\u8bc1\u636e\u7684\u57fa\u7840\uff0c\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u662f\u4e3a\u4e86\u83b7\u5f97\u66f4\u7b26\u5408\u4e34\u5e8a\u5b9e\u9645\u7684\u8bc1\u636e\uff0c\u4e8c\u8005\u7ed3\u5408\uff0c\u5728\u4e34\u5e8a\u5b9e\u8df5\u4e2d\u51fa\u201c\u771f\u77e5\u201d\u3002<\/div>\n<div>\u5927\u6570\u636e\u6e90\u4e8e\u771f\u5b9e\u4e16\u754c\uff0c\u771f\u5b9e\u4e16\u754c\u7814\u7a76\u63a8\u52a8\u5927\u6570\u636e\u7684\u53d1\u5c55\uff1b\u9ad8\u8d28\u91cf\u3001\u89c4\u8303\u5316\u7684\u6570\u636e\u662f\u4eba\u5de5\u667a\u80fd\u7684\u524d\u63d0\uff0c\u800c\u771f\u5b9e\u4e16\u754c\u6570\u636e\u662f\u4eba\u5de5\u667a\u80fd\u5e94\u7528\u53d1\u5c55\u7684\u6838\u5fc3\u8981\u7d20\u3002<\/div>\n<div>\u52a0\u5f3a\u76d1\u7ba1\u3001\u63d0\u9ad8\u5b89\u5168\u6027\uff0c\u4fc3\u8fdb\u5408\u4f5c\u548c\u5206\u4eab\u673a\u5236\u7684\u5efa\u7acb\uff0c\u6df1\u5ea6\u6316\u6398\u4e34\u5e8a\u5927\u6570\u636e\uff0c\u52a0\u5feb\u4e34\u5e8a\u8f6c\u5316\u3002<\/div>\n<div><\/div>\n<div><\/div>\n<div>2\u3001Dacomitinib\u5bf9\u5409\u975e\u66ff\u5c3c\u5728\u521d\u6cbbEGFR\u7a81\u53d8\u9633\u6027\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08NSCLC\uff09\u60a3\u8005\u4e2d\u7684\u4e09\u671f\u4e34\u5e8a\u7814\u7a76\uff1a\u4e2d\u56fd\u60a3\u8005\u4e9a\u7ec4\u5206\u6790\uff0c\u91cd\u5927\u516c\u544a\uff1a\u6b64\u7814\u7a76\u6210\u679c\u6628\u665a10\u70b9\u5728\u7ebf\u53d1\u8868\u4e8eLancteOncology<\/div>\n<div>1050\u4e2d\u56fd\u60a3\u8005-\u7f13\u89e3\u60c5\u51b5\uff1a\u4e2d\u56fd\u60a3\u8005\u7684\u7f13\u89e3\u60c5\u51b5\u7ed3\u679c\u4e0e\u5168\u4f53\u4eba\u7fa4\u7ed3\u679c\u76f8\u4e00\u81f4\uff0c\u5ba2\u89c2\u53cd\u5e94\u7387\uff08ORRs\uff09\u7ed3\u679c\u7c7b\u4f3c\uff0c\u5728\u5168\u4f53\u4eba\u7fa4\u548c\u4e2d\u56fd\u60a3\u8005\u4e2d\uff0cDacomitinib\u7ec4\u60a3\u8005\u7684\u6cbb\u7597\u73af\u8282\u6301\u7eed\u65f6\u95f4\uff08DOR\uff09\u5747\u66f4\u957f\u3002<\/div>\n<div>1050\u4e2d\u56fd\u60a3\u8005-\u5b89\u5168\u6027\u603b\u7ed3\uff1a\u603b\u4f53\u4e0a\uff0c\u4e2d\u56fd\u60a3\u8005\u4e0e\u5168\u4f53\u4eba\u7fa4\u7684\u5b89\u5168\u6027\u7ed3\u679c\u76f8\u4e00\u81f4\u3002<\/div>\n<div>1050\u4e2d\u56fd\u60a3\u8005-\u4e25\u91cd\u4e0d\u826f\u65f6\u95f4\uff08\u5927\u4e8e\u7b49\u4e8e2\u4f8b\u60a3\u8005\uff09\uff1a\u4e2d\u56fd\u60a3\u8005\u548c\u5168\u4f53\u4eba\u7fa4\u4e2d\u62a5\u544a\u6700\u591a\u7684\u4e25\u91cd\u4e0d\u826f\u65f6\u95f4\u4e3aNSCLC\u76f8\u5173\u7684\u75be\u75c5\u8fdb\u5c55\uff1b\u603b\u4f53\u4e0a\uff0c\u4e2d\u56fd\u60a3\u8005\u89c2\u5bdf\u5230\u7684\u4e25\u91cd\u4e0d\u826f\u65f6\u95f4\u6bd4\u4f8b\u4e0e\u5168\u4f53\u4eba\u7fa4\u76f8\u4f3c\uff1b\u5728\u5168\u4f53\u4eba\u7fa4\u4e2d\uff0cDacomitinib\uff08n=1\uff09\u548c\u5409\u83f2\u66ff\u5c3c\u7ec4\uff08n=1\uff0c\u4e2d\u56fd\u5927\u9646\u60a3\u8005\uff09\u5747\u67090.4%\u7684\u60a3\u8005\u88ab\u62a5\u9053\u53d1\u751f\u95f4\u8d28\u6027\u80ba\u708e\uff081LD\uff09\u3002<\/div>\n<div>\u7814\u7a76\u7ed3\u8bba\uff1a<\/div>\n<div>ARCHER 1050\u7814\u7a76\u4e2d\uff0c\u5728PFS\u548cDOR\u7b49\u6307\u6807\u65b9\u9762\uff0c\u4e2d\u56fd\u60a3\u8005\u4e0e\u5168\u4f53\u60a3\u8005\u7684\u7ed3\u679c\u76f8\u4e00\u81f4\u3002<\/div>\n<div>\u5728\u4e2d\u56fd\u60a3\u8005\u4e2d\uff1a<\/div>\n<div>1\uff09\u4e2d\u4f4dPFS\uff1a\u75be\u75c5\u8fdb\u5c55\u6216\u8005\u6b7b\u4ea1\u7684\u98ce\u9669\u4e0b\u964d\u4e8649.3%(HR of PFS per IRC=0.507)\uff0cDacomitinib 16.0\u4e2a\u6708\u5bf9\u5409\u975e\u66ff\u5c3c9.2\u4e2a\u6708\uff1b<\/div>\n<div>2\uff09\u4e2d\u4f4dDOR\uff1a\u75be\u75c5\u8fdb\u5c55\u6216\u8005\u6b7b\u4ea1\u7684\u98ce\u9669\u4e0b\u964d\u4e8662.5%(HR of DOR per IRC\u4e000.375)\uff0cDacomitinib15.6\u4e2a\u6708\u5bf9\u5409\u975e\u66ff\u5c3c8.3\u4e2a\u6708\uff1b<\/div>\n<div>3\uff09 Dacomitinib\u7ec4\u51fa\u73b0\u8179\u6cfb\u3001\u76ae\u75b9\u548c\u9ecf\u819c\u708e\u7684\u9891\u7387\u66f4\u9ad8\uff0c\u800c\u5409\u975e\u66ff\u5c3c\u7ec4\u809d\u6bd2\u6027\u53d1\u751f\u7387\u66f4\u9ad8\uff1b<\/div>\n<div>\u672c\u7814\u7a76\u4e2d\uff0cDacomitinib\u4e0d\u826f\u4e8b\u4ef6\u53d1\u751f\u7387\u4e0e\u4e4b\u524d\u7684\u7814\u7a76\u76f8\u4e00\u81f4\uff0c\u672a\u53d1\u73b0\u65b0\u7684\u4e0d\u826f\u4e8b\u4ef6\u3002<\/div>\n<div>\u76f8\u8f83\u5409\u975e\u66ff\u5c3c\uff0cDacomitinib\u7ec4\u6709\u66f4\u591a\u7684\u5242\u91cf\u8c03\u6574\u53d1\u751f\u3002<\/div>\n<div><\/div>\n<div>\u80ba\u764c\u9776\u5411\u6cbb\u7597\u4e13\u573a<\/div>\n<div>\uff089\u670827\u65e511\uff1a00-12\uff1a00\uff09<\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgIu1r29Fbv6gqGcRHtVgrawvkufIaN7MvstdmpeQYvvkLsNCDV6tNEA.png\" alt=\"RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgIu1r29Fbv6gqGcRHtVgrawvkufIaN7MvstdmpeQYvvkLsNCDV6tNEA\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div>1\u3001\u5173\u4e8e\u514b\u5511\u66ff\u5c3c\u4e00\u7ebf\u6cbb\u7597ROS-1\u9633\u6027\u80ba\u764c\u7684\u53ef\u7528\u6570\u636e\u5f88\u6709\u9650<\/div>\n<div>\u7cbe\u51c6\u533b\u5b66\u5305\u62ec\u9776\u70b9\u7cbe\u51c6\u548c\u6cbb\u7597\u65f6\u673a\u7cbe\u51c6<\/div>\n<div>\u9776\u5411\u7cbe\u51c6\u4f9d\u8d56\u4e8e\u751f\u7269\u6807\u5fd7\u7269\u7684\u9009\u62e9\uff0c\u5305\u62ecEGFR\u7a81\u53d8\u3001LAR\u6613\u4f4d\u53ca\u5176\u4ed6\u7f55\u89c1\u7a81\u53d8<\/div>\n<div>\u9488\u5bf9EGFR\u7684\u7cbe\u51c6\u533b\u5b66<\/div>\n<div>-FLAURA\u8bc1\u5b9e\u4e00\u7ebf\u5965\u5e0c\u66ff\u5c3c\u6539\u5584PFS<\/div>\n<div>-OS\u83b7\u76ca\u7684\u6700\u4f73\u987a\u5e8f\u8fd8\u6709\u5f85\u5b9a\u4e49<\/div>\n<div>\u9488\u5bf9\u7f55\u89c1\u7a81\u53d8\u7684\u7cbe\u51c6\u533b\u5b66<\/div>\n<div>&#8211; ROS1\u548cBRAF\u9633\u6027\u80bf\u7624\u90fd\u4e0e\u5176\u63a5\u53d7\u5404\u81ea\u7684TKI\u6cbb\u7597\u9ad8\u7f13\u89e3\u7387\u76f8\u5173<\/div>\n<div>&#8211; \u4e00\u7ebf\u4f7f\u7528\u8fd9\u4e9bTKI\u5e76\u975e\u5f3a\u5236\u6027\u63a8\u8350\uff0c\u56e0\u4e3a\u6570\u636e\u4ecd\u7f3a\u4e4f<\/div>\n<div>2\u3001\u540e\u7ebf\u6cbb\u7597\uff0c\u5965\u5e0c\u66ff\u5c3c\u5df2\u4e3at790M+\u6cbb\u7597\u6807\u51c6<\/div>\n<div>3\u3001AURA\u4e00\u7ebf\u961f\u5217\uff1a\u5965\u5e0c\u66ff\u5c3c\u5c1d\u8bd5\u6cbb\u7597EGFR\u7a81\u53d8,\u4e0d\u9650\u4e8eT790M+<\/div>\n<div>4\u3001FLAURA\uff1a<\/div>\n<div>\u5bf9\u6bd4\u6807\u51c6\u6cbb\u7597\uff0c\u5965\u5e0c\u66ff\u5c3c\u663e\u8457\u6539\u5584\u4e86PFS\uff0cHR 0.46\uff0cP\uff1c0.0001<\/div>\n<div>\u4e2d\u671f\u7684OS\u5206\u6790\u63d0\u793a\u6f5c\u5728\u83b7\u76ca\uff0cHR 0.63\uff0cP=0.0068<\/div>\n<div>\u5b89\u5168\u6027\u4e0e\u6807\u51c6\u6cbb\u7597\u53ef\u6bd4\uff0c\u22653\u7ea7\u6bd2\u6027\u548c\u4e2d\u6b62\u6cbb\u7597\u6bd4\u4f8b\u66f4\u4f4e<\/div>\n<div>\u5965\u5e0c\u66ff\u5c3c\u65f6\u65b0\u7684EGFR\u7a81\u53d8\u665a\u671fNSCLC\u4e00\u7ebf\u6807\u51c6\u6cbb\u7597<\/div>\n<div><\/div>\n<div>\u80bf\u7624\u533b\u5e08\u4e0e\u5927\u6570\u636e\u4e13\u573a<\/div>\n<div>\uff089\u670827\u65e514\uff1a30-17\uff1a00\uff09<\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgrQNIEqgX1s3UY18a0icJw00oaiaefEwQStdQSZceZoRSHrsPoyEWK1uQ.png\" alt=\"RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgrQNIEqgX1s3UY18a0icJw00oaiaefEwQStdQSZceZoRSHrsPoyEWK1uQ\"\/><\/figure><\/div>\n\n<\/div>\n<div>1\u3001\u4e8e\u519b \u4e2d\u56fd\u79d1\u5b66\u9662\u5317\u4eac\u57fa\u56e0\u7ec4\u7814\u7a76\u6240\u00a0<\/div>\n<div>\u8bdd\u9898\uff1a\u300a\u4e34\u5e8a\u5927\u6570\u636e\u4e0e\u7cbe\u51c6\u6cbb\u7597\u300b<\/div>\n<div>\u5355\u7ec6\u80de\u6c34\u5e73RNA\u76f4\u6d4b\u6280\u672f\u51b3\u5b9a\u65b0\u7684\u4eba\u7c7bRNA\u7ec4\u548c\u4eba\u7c7b\u8868\u89c2\u7ec4\u5b66\u4e24\u4e2a\u6838\u5fc3\u8ba1\u5212\u7684\u542f\u52a8\u3002<\/div>\n<div>\u00a0 \u00a0 \u00a0 \u00a01\uff09\u5355\u7ec6\u80deRNA\u7ec4\uff1a\u5b9e\u73b0\u5168\u90e8RNA\u7684\u5b9a\u91cf\u3001\u5b9a\u4f4d<\/div>\n<div>\u00a0 \u00a0 \u00a0 \u00a02\uff09 \u00a0\u7ec6\u80de\u4e0e\u5668\u5b98RNA\u7ec4\uff1a\u751f\u7406+\u75c5\u7406\u72b6\u6001<\/div>\n<div>\u00a0 \u00a0 \u00a0 \u00a03\uff09\u764c\u75c7\u7ec6\u80de\u4e0e\u7ec4\u7ec7\u7ec4\uff1a<\/div>\n<div>\u00a0 \u00a0 \u00a0 &#8211; \u542f\u52a8\u201c\u4eba\u7c7b\u7ec6\u80deRNA\u7ec4\u4e0e\u8868\u89c2\u7ec4\u8ba1\u5212\u201d<\/div>\n<div>\u00a0 \u00a0 \u00a0 &#8211; \u542f\u52a8\u201c\u4eba\u7c7b\u7ec4\u7ec7\u4e0e\u5668\u5b98\u53d1\u80b2\u7ec4\u8ba1\u5212\u201d<\/div>\n<div>\u7cbe\u51c6\u533b\u5b66\u4f9d\u8d56\u4e8e\u6b63\u786e\u7684\u6982\u5ff5\u3001\u51c6\u786e\u7684\u673a\u7406\u3001\u53ef\u9760\u7684\u8bca\u65ad\u548c\u6709\u6548\u7684\u6cbb\u7597\u3002<\/div>\n<div>\u00a0<\/div>\n<div>2\u3001\u738b\u4e9a\u677e\u00a0\u56fd\u5bb6\u4fe1\u606f\u4e2d\u5fc3\u5927\u6570\u636e\u7ba1\u7406\u5e94\u7528\u4e2d\u5fc3<\/div>\n<div>\u8bdd\u9898\uff1a\u300a\u533a\u5757\u94fe\u6280\u672f\u5728\u533b\u7597\u5927\u6570\u636e\u9886\u57df\u7684\u5e94\u7528\u300b<\/div>\n<div>\u5f71\u54cd\u5927\u6570\u636e\u884c\u4e1a\u53d1\u5c55\u7684\u56db\u5927\u95ee\u9898\uff1a\u6570\u636e\u5b64\u5c9b\u95ee\u9898\u3001\u6570\u636e\u6d41\u901a\u95ee\u9898\u3001\u6570\u636e\u589e\u503c\u95ee\u9898\u3001\u6570\u636e\u5b89\u5168\u95ee\u9898\u3002<\/div>\n<div>\u6570\u636e\u533a\u5757\u8fde\uff1a<\/div>\n<div>\u00a0 \u00a0 \u00a0 \u00a0\u4ee5\u65f6\u95f4\u987a\u5e8f\u8bb0\u5f55\u67d0\u79cd\u5168\u8fc7\u7a0b\u884c\u4e3a\u7684\u94fe\u5f0f\u6570\u636e\u7ed3\u6784\u3002\u7528\u4e8e\u8bb0\u5f55\u6570\u636e\u4ea4\u6362 \u00a0 \u00a0 \u00a0 \uff08switch\uff0cnot trade\uff09\u7684\u5168\u8fc7\u7a0b\uff0c\u4fdd\u969c\u6570\u636e\u5728\u5171\u4eab\u5f00\u653e\u8fc7\u7a0b\u4e2d\u7684\u5b89\u5168\u3001\u53ef\u4fe1\u3001\u53ef\u6eaf\u7684 \u533a\u5757\u94fe\u57fa\u7840\u64cd\u4f5c\u7cfb\u7edf\u3002<\/div>\n<div>\u00a0 \u00a0 \u00a0 &#8211; \u4e0d\u540c\u4e8e\u76ee\u524d\u6bd4\u7279\u5e01\u3001\u4ee5\u592a\u574a\u7b49\u533a\u5757\u94fe\u5e73\u53f0\uff1b<\/div>\n<div>\u00a0 \u00a0 \u00a0 &#8211; \u66f4\u4e0d\u540c\u4e8e\u7269\u6d41\uff0c\u5236\u9020\u4e1a\u7684\u533a\u5757\u94feApp\u5e94\u7528\uff1b<\/div>\n<div>\u00a0 \u00a0 \u00a0 &#8211; \u5728\u6280\u672f\u548c\u6218\u7565\u4e0a\u5c5e\u4e8e\u89c2\u6709\u533a\u5757\u94fe\u7684\u76f2\u533a\u3002<\/div>\n<div>\u533a\u5757\u94fe\u6280\u672f\u7684\u5b89\u5168\u591a\u65b9\u4fe1\u4efb\uff1a<\/div>\n<div>1\uff09\u94fe\u4e0a\uff08OnChain\uff09he \u94fe\u4e0b\uff08OffChain\uff09\u534f\u540c\u7ba1\u7406\uff0c\u4fdd\u62a4\u9690\u79c1\u6027\u3002\u56e0\u4e3a\u6570\u636e\u672c\u8eab\u662f\u94fe\u4e0b\u7684\uff0c\u7f51\u7edc\u8282\u70b9\u5e76\u4e0d\u80fd\u770b\u5230\uff1b\u94fe\u4e0b\u6570\u636e\u662f\u6570\u636e\u94fe\u4e0a\u8bb0\u5f55\u800c\u4f7f\u7528\u7684\u3002<\/div>\n<div>2\uff09\u52a0\u5bc6\u4e0e\u9009\u62e9\u6027\u5171\u4eab\u6280\u672f\u3002\u6570\u636e\u5728\u6bcf\u4e2a\u8282\u70b9\u8fdb\u884c\u52a0\u5bc6\u526f\u672c\uff0c\u6570\u636e\u8bbf\u95ee\uff0c\u91c7\u7528\u9009\u62e9\u6027\u5171\u4eab\u6280\u672f\u3002<\/div>\n<div>3\uff09POS\u6a21\u5f0f\u4e0b\u7684\u4e3b\u6743\u533a\u5757\u94fe\u6280\u672f\u3002\u7531\u5de5\u4f5c\u8fde\u8bc1\u660e\uff0c\u8f6c\u53d8\u4e3a\u5de5\u4f5c\u80fd\u529b\u8bc1\u660e\uff1b\u7531\u516c\u5171\u533a\u5757\u94fe\u57fa\u7840\u8bbe\u65bd\uff0c\u8f6c\u53d8\u4e3a\u653f\u5e9c\u5f15\u5bfc\u7684\u53ef\u9760\u3001\u5b89\u5168\u533a\u5757\u94fe\u57fa\u7840\u8bbe\u65bd\u3002<\/div>\n<div>4\uff09\u6570\u636e\u5e94\u7528\u72b6\u6001\u4e0b\u7684\u667a\u80fd\u5408\u7ea6\u3002\u79c1\u6709\u94fe\u3001\u8054\u76df\u94fe\u3001\u516c\u5171\u94fe\u7684\u6709\u673a\u7ed3\u5408\u3002<\/div>\n<div>\u00a0<\/div>\n<div>3\u3001\u5434\u4e00\u9f99\u6559\u6388 \u00a0\u4e3b\u4efb\u533b\u5e08\u3001\u535a\u58eb\u751f\u5bfc\u5e08\u5e7f\u4e1c\u7701\u4eba\u6c11\u533b\u9662\u00a0\u00a0\u00a0<\/div>\n<div>\u8bdd\u9898\uff1a\u300a\u771f\u5b9e\u4e16\u754c\u7814\u7a76RWS\u6307\u5357\u7814\u8ba8\u300b<\/div>\n<div>\u201c\u771f\u5b9e\u4e16\u754c\u201d\u7814\u7a76\uff08Real-World Study\uff0cRWS\uff09\u8d77\u6e90\u4e8e\u5b9e\u7528\u6027\u7684\u4e34\u5e8a\u7814\u7a76\u8bd5\u9a8c\uff0c\u65e9\u671f\u5c5e\u4e8e\u836f\u7269\u6d41\u884c\u75c5\u5b66\u8303\u7574\u3002<\/div>\n<div>\u8fc7\u53bb23\u5e74\uff0cRWS\u70ed\u5ea6\u6301\u7eed\u5347\u9ad8<\/div>\n<div>RWS vs RCT\uff1a\u6570\u636e\u7684\u83b7\u5f97\u65b9\u5f0f\u53ca\u7814\u7a76\u65b9\u6cd5\u7684\u5dee\u5f02<\/div>\n<div>\u771f\u5b9e\u4e16\u754c\u6570\u636e\u4e0e\u771f\u5b9e\u4e16\u754c\u8bc1\u636e\u662f\u4e24\u4e2a\u4e0d\u540c\u7684\u6982\u5ff5<\/div>\n<div>\u6211\u56fd\u533b\u7597\u6570\u636e\u7684\u73b0\u72b6<\/div>\n<div>\u00a0 \u00a0 \u00a0&#8211;\u00a0\u00a0\u6570\u636e\u8d28\u91cf\uff1a\u771f\u5b9e\u4e16\u754c\u6570\u636e\u91cf\u5927\uff0c\u4f46\u662f\u8bc1\u636e\u7ea7\u522b\u4e0d\u9ad8\u3002<\/div>\n<div>\u00a0 \u00a0 \u00a0 &#8211;\u00a0\u6570\u636e\u6807\u51c6\uff1a\u4e0d\u540c\u533b\u7597\u673a\u6784\u6570\u636e\u5f62\u5f0f\u4e0d\u540c\uff0c\u6807\u51c6\u5316\u7a0b\u5ea6\u4f4e\u3002<\/div>\n<div>\u00a0 \u00a0 \u00a0 &#8211;\u00a0\u6570\u636e\u7ef4\u5ea6\uff1a\u6570\u636e\u7c7b\u578b\u591a\uff0c\u4f46\u662f\u4e0d\u7cfb\u7edf\u4e0d\u5168\u9762<\/div>\n<div>\u5206\u5b50\u6807\u5fd7\u7269\u4e0e\u4e2a\u4f53\u5316\u8bca\u7597\u8bba\u575b1<\/div>\n<div>\uff089\u670827\u65e514\uff1a30-17\uff1a00\uff09<\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgpQEqAbRJhntvQY67L5gVYrxFluA0ACiaj4C9fuVKrseenDNtkF60iclg.png\" alt=\"RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgpQEqAbRJhntvQY67L5gVYrxFluA0ACiaj4C9fuVKrseenDNtkF60iclg\"\/><\/figure><\/div>\n\n<\/div>\n<div>1\u3001\u5f20\u7eea\u8d85 \u00a0\u535a\u58eb\u3001\u7855\u58eb\u751f\u5bfc\u5e08\u00a0 \u5e7f\u4e1c\u7701\u4eba\u6c11\u533b\u9662<\/div>\n<div>\u8bdd\u9898\uff1a\u300a\u80bf\u7624\u514d\u75ab\u68c0\u67e5\u70b9\u6291\u5236\u5242\u7684\u7cbe\u51c6\u6cbb\u7597\u8fdb\u7a0b\u300b<\/div>\n<div>\u591a\u9879\u7814\u7a76\u8bc1\u5b9e\u514d\u75ab\u6cbb\u7597\u4e3a\u80bf\u7624\u60a3\u8005\u5e26\u6765\u751f\u5b58\u83b7\u76ca<\/div>\n<div>CheckMate 026\uff1a<\/div>\n<div>\u00a0 \u00a0 \u00a0 &#8211; \u9ad8TMB\u662fNSCLC\u514d\u75ab\u6cbb\u7597\u7597\u6548Biomarker<\/div>\n<div>\u00a0 \u00a0 \u00a0 &#8211; TMB\u9884\u6d4b\u4f18\u4e8ePD-L1\u8868\u8fbe\u6c34\u5e73<\/div>\n<div>PD-L1\u4f5c\u4e3abiomarker\u7684\u5c40\u9650\u6027\uff1a\u53ca\u65f6\u65f6PD-L1\u9634\u6027\u60a3\u8005\uff0cIO\u4f18\u4e8e\u6807\u51c6\u5316\u7597<\/div>\n<div>2\uff09PDL1\u4e4b\u5916\u7684TMB\u7b49\u5982\u4f55\u66f4\u7cbe\u51c6\uff1f<\/div>\n<div>\u80bf\u7624\u7a81\u53d8\u8d1f\u8377\u662f\u5bf9\u57fa\u56e0\u7ec4\u4e0d\u7a33\u5b9a\u6027\u7684\u8861\u91cf<\/div>\n<div>\u78b1\u57fa\u7a81\u53d8\u5bf9\u591a\u80bd\u94fe\u4e2d\u6c28\u57fa\u9178\u5e8f\u5217\u7684\u5f71\u54cd<\/div>\n<div>\u6d4b\u5e8f\u9886\u57df\u7684\u8fdb\u5c55\u4f7f\u5f97\u68c0\u6d4b\u57fa\u56e0\u7ec4\u7a81\u53d8\u6210\u4e3a\u73b0\u5b9e<\/div>\n<div>TMB\u7684\u8bc4\u4f30:\u4e8c\u4ee3\u6d4b\u5e8f\uff08NGS\uff09\u5e94\u7528<\/div>\n<div>TMB\u7684\u6d4b\u5b9a:WES VsTargeted gene panel<\/div>\n<div>Foundation ONE \u91c7\u7528\u57fa\u56e0\u7ec4\u5206\u6790\u65b9\u6cd5\u6d4b\u5b9aTMB<\/div>\n<div>3\uff09TMB\u4e0eIO\u7597\u6548\u9884\u6d4b<\/div>\n<div>PD-1\/PD-L1\u6291\u5236\u5242\u5728\u5404\u7624\u79cd\u7684\u7597\u6548\u5747\u4e0eTMB\u6210\u6b63\u76f8\u5173<\/div>\n<div>4\uff09TMB\u4e2d\u7684\u529f\u80fd\u6210\u5206\u662f\u4ec0\u4e48\uff1f<\/div>\n<div>\u65b0\u6297\u539f\uff1a\u9884\u6d4b\u3001\u75ab\u82d7\u3001\u9776\u70b9<\/div>\n<div>\u514d\u75ab\u76f8\u5173\u7684\u7a81\u53d8<\/div>\n<div>5\uff09\u603b\u7ed3\uff1a<\/div>\n<div>\u80ba\u764cIO\u5728\u4e8c\u7ebf\u3001\u4e00\u7ebf\u3001\u4e2d\u665a\u671f\u540c\u6b65\u653e\u5316\u7597\u540e\u4f7f\u7528\u5747\u6709\u7a81\u7834\u6027\u7814\u7a76\u7ed3\u679c\u3002PDL1\u4f34\u968f\u8bca\u65ad\u5df2\u6216USFDA\u6279\u51c6\uff0c\u4f46\u5728\u4e34\u5e8a\u7684\u7cbe\u51c6\u6027\u5b58\u5728\u4e0d\u8db3\u3002<\/div>\n<div>TMB\u662fIO\u9884\u6d4b\u56e0\u5b50\u7684\u70ed\u70b9\u3002TMB\u53ef\u4ee5\u91c7\u7528NGS\u8fdb\u884c\u68c0\u6d4b\uff0c\u4e5f\u53ef\u4ee5\u68c0\u6d4b\u8840\u6db2bTMB\u3002bTMB\u4e0ePD-L1\u7684\u8868\u8fbe\u5448\u5f31\u76f8\u5173\u3002TMB\u8054\u5408PD-L1\u591a\u7684\u8868\u8fbe\u65f6\u6f5c\u5728\u7684IO\u7597\u6548\u9884\u6d4b\u56e0\u5b50\u3002<\/div>\n<div>TMB\u68c0\u6d4b\u6ca1\u6709\u6807\u51c6\u65b9\u6cd5\u53ca\u660e\u786e\u7684cut-off\u503c\uff0c\u666e\u53ca\u5316\u9762\u4e34\u8bf8\u591a\u6311\u6218\uff0c\u5e76\u9700\u8981\u524d\u77bb\u6027\u7684\u4e34\u5e8a\u7814\u7a76\u8bc1\u660eTBM\u4f5c\u4e3abiomarker\u7684\u4e34\u5e8a\u83b7\u76ca\u3002<\/div>\n<div>TMB\u7684\u7814\u7a76\u65b9\u5411\u5305\u62ec\uff1aBtmb\u65b9\u6cd5\u4e0e\u9a8c\u8bc1\u3001\u529f\u80fd\u6210\u5206\u3001TMB\u8054\u5408\u5176\u5b83biomarker\u7684\u53ef\u884c\u6027\u3002<\/div>\n<div>\u9700\u8981\u66f4\u5e7f\u6cdb\u7684\u5206\u6790IO\u7684\u6f5c\u5728\u9884\u6d4b\u56e0\u5b50\u3002<\/div>\n<div>\u7cbe\u51c6\u533b\u5b66\u8bba\u575b1<\/div>\n<div>\uff089\u670827\u65e514\uff1a30-17\uff1a00\uff09<\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgRiaocuJbH7qsuTUubyTZibFBpwvNdSaiadekPxE8TdLsLfHib2WIOVRHfQ.png\" alt=\"RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgRiaocuJbH7qsuTUubyTZibFBpwvNdSaiadekPxE8TdLsLfHib2WIOVRHfQ\"\/><\/figure><\/div>\n\n<\/div>\n<div>1\u3001\u5468\u5f69\u5b58\u00a0\u00a0\u6559\u6388 \u00a0\u4e0a\u6d77\u5e02\u80ba\u79d1\u533b\u9662\u80bf\u7624\u79d1\u4e3b\u4efb<\/div>\n<div>\u8bdd\u9898\uff1a\u300a\u7cbe\u51c6\u533b\u5b66\u5728\u665a\u671f\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\u4e2d\u7684\u5e94\u7528\u300b<\/div>\n<div><\/div>\n<div>\u4e3b\u8981\u4fa7\u91cd\u80ba\u764c\u8bca\u65ad\uff0c\u8bca\u65ad\u5e94\u8be5\u8d2f\u7a7f\u6574\u4e2a\u6cbb\u7597\u8fc7\u7a0b\u7edd\u4e0d\u662f\u864e\u5934\u86c7\u5c3e\u3002<\/div>\n<div>\u00a0\u7cbe\u51c6\u533b\u8fbd\u662f\u6539\u5584\u80ba\u764c\u9884\u540e\u7684\u91cd\u8981\u7b56\u7565\u00a0<\/div>\n<div>\u7cbe\u51c6\u6cbb\u7597\u7684\u57fa\u7840\u662f\u7cbe\u51c6\u8bca\u65ad\u00a0<\/div>\n<div>\u5206\u5b50\u6807\u5fd7\u7269\u53ca\u8010\u836f\u76f8\u5173\u57fa\u56e0\u68c0\u6d4b\u662f\u7cbe\u51c6\u8bca\u65ad\u7684\u91cd\u8981\u5185\u5bb9\u00a0<\/div>\n<div>CTC,ctDNA\u53ef\u7528\u4e8e\u68c0\u6d4b\u53ca\u7597\u6548\u76d1\u6d4b<\/div>\n<div>NGS\u7684\u591a\u57fa\u56e0\u68c0\u6d4b\u662f\u5c06\u6765\u53d1\u5c55\u65b9\u5411<\/div>\n<div><\/div>\n<div>2\u3001\u9646\u52b2\u677e\u00a0\u6559\u6388 \u4e0a\u6d77\u4ea4\u901a\u5927\u5b66\u4ec1\u6d4e\u533b\u9662<\/div>\n<div>\u8bdd\u9898\uff1a\u300a\u7cbe\u51c6\u533b\u5b66\u5728\u4e73\u817a\u764c\u4e34\u5e8a\u8bca\u7597\u4e2d\u7684\u5e94\u7528\u300b<\/div>\n<div>\u672a\u6765\u624b\u672f\u7684\u7cbe\u51c6\u5207\u9664\uff0c\u4e0d\u5e94\u4ece\u5668\u5b98\u8003\u8651\uff0c\u5e94\u4ece\u57fa\u56e0\u89d2\u5ea6\u8003\u8651\u548c\u51b3\u7b56<\/div>\n<div>\u57fa\u56e0\u68c0\u6d4b\u53ef\u4ee5\u5e2e\u52a9\u533b\u751f\u7cbe\u51c6\u51b3\u7b56\u5668\u5b98\u662f\u5426\u9700\u8981\u5207\u9664<\/div>\n<div>\u4e2a\u4f53\u5316\u6cbb\u7597\u7684\u4e0d\u540c\u9636\u6bb5\uff0c\u76ee\u524d\u662f\u5206\u7c7b\u6cbb\u7597\uff0c\u672a\u6765\u662f\u4e2a\u4f53\u6cbb\u7597<\/div>\n<div>\u7cbe\u51c6\u8bca\u65ad\u6307\u5bfc\u4e0b\u672a\u6765\u8bca\u6cbb\u53d8\u5316\u6446\u8131\u5668\u5b98\uff0c\u5f62\u6001\u9650\u5236<\/div>\n<div>\u75c5\u60c5\u53d8\u5316\u7684\u5b9e\u65f6\u76d1\u6d4b<\/div>\n<div><\/div>\n<div><\/div>\n<div>3\u3001\u738b\u6d77\u6d9b\u00a0\u6559\u6388 \u5929\u6d25\u533b\u79d1\u5927\u5b66\u7b2c\u4e8c\u533b\u9662\u80bf\u7624\u79d1\uff0c\u5929\u6d25\u5e02\u6ccc\u5c3f\u5916\u79d1\u7814\u7a76\u6240<\/div>\n<div>\u8bdd\u9898\uff1a\u300a\u665a\u671f\u96be\u6cbb\u6027\u80bf\u7624\u7cbe\u51c6\u533b\u5b66\u8fdb\u5c55\u4e0e\u4e34\u5e8a\u5b9e\u8df5\u63a2\u7d22\u300b<\/div>\n<div>1\uff09\u96be\u6cbb\u6027\u80bf\u7624\u7684\u8303\u56f4\uff1a<\/div>\n<div>\u5e38\u89c1\u6076\u6027\u80bf\u7624\u7ecf\u6807\u51c6\u591a\u7ebf\u6cbb\u7597\u540e\u7ee7\u7eed\u8fdb\u5c55\u7684\u540e\u7ebf\u6cbb\u7597<\/div>\n<div>\u65e0\u6307\u5357\u63a8\u8350\u6807\u51c6\u65b9\u6848\u7684\u5c11\u89c1\u6076\u6027\u80bf\u7624\u7684\u521d\u59cb\u6cbb\u7597<\/div>\n<div>\u5e74\u8001\u4f53\u5f31\u3001\u8111\u8f6c\u79fb\u6216\u6709\u8f83\u4e25\u91cd\u5408\u5e76\u75c7\u6216 ECOG\u8bc4\u5206 3-4\u5206\u7684\u7ec8\u672b\u671f\u60a3\u8005\u7684\u6cbb\u7597<\/div>\n<div>\u4e34\u5e8a\u4e0a\u96be\u6cbb\u6027\u80bf\u7624\u60a3\u8005\u7684\u6cbb\u7597\u7b56\u7565\u9009\u62e9\u5e38\u5e38\u4e3e\u6b65\u7ef4\u8270\uff0c\u5f02\u75c5\u540c\u6cbb\u3002\u6709\u671b\u6210\u4e3a\u7a81\u7834\u96be\u6cbb\u6027\u80bf\u7624\u6cbb\u7597\u74f6\u9888\u5229\u5668<\/div>\n<div>2\uff092017\u7cbe\u51c6\u533b\u7597\u53d1\u5c55\u7684\u4e09\u5927\u8d8b\u52bf\uff1a<\/div>\n<div>\u7cbe\u51c6\u533b\u7597\u5728\u4e0d\u540c\u9886\u57df\u4e0d\u65ad\u6df1\u5165<\/div>\n<div>\u7cbe\u51c6\u533b\u7597\u5728\u5927\u6570\u636e\u652f\u6491\u4e0b\u8d70\u5411\u667a\u80fd\u533b\u7597<\/div>\n<div>\u7cbe\u51c6\u533b\u7597\u4ece\u7406\u8bba\u7814\u7a76\u8d70\u5411\u793a\u8303\u5e94\u7528<\/div>\n<div><\/div>\n<div><\/div>\n<div>\u60a8\u53ef\u80fd\u8fd8\u4f1a\u611f\u5174\u8da3\u7684<\/div>\n<div><\/div>\n<div><\/div>\n<div><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMzE4MzU3NA==&amp;mid=2651633425&amp;idx=1&amp;sn=c03a5556ac543883f9109a42e9e1a567&amp;scene=21#wechat_redirect\" \/>\u89e3\u653e\u519b\u603b\u533b\u9662-\u6768\u4e91\u751f<\/a><\/div>\n<div><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMzE4MzU3NA==&amp;mid=2651632522&amp;idx=1&amp;sn=7a868a53c9fb8430bcd1a91eec4c8be0&amp;scene=21#wechat_redirect\" \/>\u4e13\u8bbf\u9510\u7fcc\u751f\u7269\u521b\u59cb\u4eba-\u79e6\u6960<\/a><\/div>\n<div><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMzE4MzU3NA==&amp;mid=2651632712&amp;idx=1&amp;sn=b95c8f8575957a2ef8ccc02c9f27c1e4&amp;scene=21#wechat_redirect\" \/>\u300a\u4e09\u4eba\u884c\u300b\u9646\u7956\u5b8f\/\u84dd\u707f\u8f89\/\u8d75\u67cf\u95fb<\/a><\/div>\n<div><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMzE4MzU3NA==&amp;mid=2651633217&amp;idx=1&amp;sn=80cb4cf09c37289196ef472bd2183ef4&amp;scene=21#wechat_redirect\" \/>\u5357\u4eac\u603b\u533b\u9662-\u674e\u5b81<\/a><\/div>\n<div><a href=\"http:\/\/mp.weixin.qq.com\/s?__biz=MzIzMzE4MzU3NA==&amp;mid=2651633490&amp;idx=1&amp;sn=8129f15ea70268fb93d09977d25d2ae6&amp;scene=21#wechat_redirect\" \/>\u5357\u4eac\u533b\u79d1\u5927\u5b66\u7b2c\u4e8c\u9644\u5c5e\u533b\u9662-\u5f20\u53d1\u660e<\/a><\/div>\n<div><a href=\"https:\/\/mp.weixin.qq.com\/s?__biz=MzIzMzE4MzU3NA==&amp;mid=2651630782&amp;idx=1&amp;sn=27bfce74ef06851fb3ef7873728e3e81&amp;scene=21#wechat_redirect\" \/>\u4eba\u4f53\u7b2c\u4e8c\u5957\u57fa\u56e0\u7ec4-\u80a0\u9053\u5fae\u751f\u7269\u7ec4<\/a><\/div>\n<div><\/div>\n<div><\/div>\n<div><\/div>\n<div>\u6570\u5b57\u5065\u5eb7\u884c\u4e1a\u4fe1\u606f\u6570\u636e\u5e93<\/div>\n<div><\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgtwHFZich7Mkpn1icjvYYYxXRDViar6LG57dnbemvKEABjnbIbD3mFh2xg.jpeg\" alt=\"RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfgtwHFZich7Mkpn1icjvYYYxXRDViar6LG57dnbemvKEABjnbIbD3mFh2xg\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div><\/div>\n<div>\n\n<div class=\"wp-block-image aligncenter\">\n<figure class=\"\"><img decoding=\"async\" src=\"https:\/\/www.geneclub.net.cn\/wp-content\/uploads\/images\/RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfggACN9HiaErH4gXdhT1rGjXrGOpcGb2yWwKlF3VO9l7Dz9E2OP70O2iag.gif\" alt=\"RmFicvQBAkgB2Wkia2jicswicwcVoFyjgcfggACN9HiaErH4gXdhT1rGjXrGOpcGb2yWwKlF3VO9l7Dz9E2OP70O2iag\"\/><\/figure><\/div>\n\n<\/div>\n<div><\/div>\n<div><\/div>","protected":false},"excerpt":{"rendered":"<p>\u5173\u952e\u5b57\uff1a\u4e73\u817a\u764c\u5927\u6570\u636e\u3001\u80ba\u764c\u9776\u5411\u6cbb\u7597\u3001\u80bf\u7624\u533b\u5e08 \u5206\u5b50 &hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[996],"tags":[1841,2124,2125],"class_list":["post-11076","post","type-post","status-publish","format-standard","hentry","category-news","tag-1841","tag-2124","tag-2125"],"_links":{"self":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/11076","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/comments?post=11076"}],"version-history":[{"count":3,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/11076\/revisions"}],"predecessor-version":[{"id":14412,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/posts\/11076\/revisions\/14412"}],"wp:attachment":[{"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/media?parent=11076"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/categories?post=11076"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.geneclub.net.cn\/index.php\/wp-json\/wp\/v2\/tags?post=11076"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}